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325:. The aim of the mission was to provide proof of concept for the MinION's functionality in a microgravity environment. During the mission, ISS crew members successfully sequenced DNA from bacteria, bacteriophage and rodents from samples prepared on Earth. Maintaining the MinION device as a research facility on the space station holds the potential to support a number of additional science investigations, any of which could have Earth based applications.
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29:
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McIntyre, Alexa B. R.; Rizzardi, Lindsay; Yu, Angela M.; Rosen, Gail L.; Alexander, Noah; Botkin, Douglas J.; John, Kristen K.; Castro-Wallace, Sarah L.; Burton, Aaron S. (10 December 2015). "Nanopore
Sequencing in Microgravity".
356:
VolTRAX: this device, currently in development, is designed for automated sample preparation so that users do not need a laboratory or lab skills to run the device. Registration for the early access program was opened in
October
345:
MinION: this harmonica-sized portable protein nanopore sequencing USB device has been commercially available since May 2015 after having been launched initially through an early access program, the MinION Access
Program
352:
PromethION: this desktop, high throughput device will be available through an access program that opened for registration in July 2015. The device contains channels for 144,000 nanopores (in comparison to MinION’s
349:
GridION X5: this desktop device has been commercially available since March 2017. The device processes up to five MinION Flow Cells and enables generation of up to 100 Gb of data per run.
298:
In March 2016 the company announced a chemistry upgrade to its nanopore sequencing product 'R9', using a protein nanopore in collaboration with the laboratory of Han Remaut (VIB/
638:
652:
1242:
360:
Metrichor: this spinout company from Oxford
Nanopore was set up to provide end to end solutions for biological analyses, using nanopore sensing technologies.
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305:
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64:
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Top view of a closed Oxford
Nanopore Technologies MinION sequencer showing how it is small enough to be held in one hand
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256:
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1004:
591:
288:
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Mikheyev, A. S.; Tin, M. M. Y. (2014). "A first look at the Oxford
Nanopore MinION sequencer".
255:
products (including the portable DNA sequencer, MinION) for the direct, electronic analysis of
39:
653:"VIB announces collaboration with Oxford Nanopore Technologies on new DNA sequencing nanopore"
580:
384:
292:
53:
1053:"Oxford Nanopore CTO Clive Brown's Talk at London Calling: MinION ASIC, volTRAX, promethION"
874:"IP Group PLC – Portfolio company Oxford Nanopore announces £70m fundraising – IP Group PLC"
1146:
837:
775:
439:
388:
272:
899:
Loman, Nicholas J; Watson, Mick (2015). "Successful test launch for nanopore sequencing".
8:
302:). The company stated in a webcast that R9 is designed to improve error rates and yield.
252:
132:
81:
841:
932:
556:
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512:
464:
268:
951:"Oxford Nanopore Launches GridIon X5 Nanopore Sequencer, Details Product Improvements"
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504:
468:
456:
333:
1030:
639:"London Stock Exchange welcomes Oxford Nanopore Technologies plc to the Main Market"
547:
437:
Eisenstein, M. (2012). "Oxford
Nanopore announcement sets sequencing sector abuzz".
363:
SmidgION: a mobile phone sequencer announced in May 2016, currently in development.
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In July 2016, a MinION nanopore sequencer was included on the ninth NASA/
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28:
1113:
850:
825:
1139:"SmidgION - Products & services - Oxford Nanopore Technologies"
780:
284:
1096:"Oxford Nanopore: we want to create the internet of living things"
702:"Next SpaceX Commercial Cargo Launch Now No Earlier Than July 18"
678:
376:
248:
318:
136:
159:
1207:
1027:"Specifications - Community - Oxford Nanopore Technologies"
532:"Poretools: A toolkit for analyzing nanopore sequence data"
367:
These products are intended to be used for the analysis of
233:
372:
368:
772:
797:"Data from pocket-sized genome sequencer unveiled"
579:
321:commercial cargo resupply services mission to the
313:with a MinION sequencer on the ISS in August 2016.
1214:
1161:
826:"Pint-sized DNA sequencer impresses first users"
413:"Annual Results for year ended 31 December 2023"
892:
749:"First DNA Sequencing in Space a Game Changer"
1243:Companies listed on the London Stock Exchange
279:, Gordon Sanghera, and Spike Willcocks, with
1167:
823:
794:
529:
295:on 30 September 2021, under the ticker ONT.
1170:"Nanopore genome sequencer makes its debut"
1088:
898:
486:
1001:"Community - Oxford Nanopore Technologies"
436:
341:The main products of Oxford Nanopore are:
27:
1181:
849:
808:
779:
555:
407:
405:
403:
1238:Technology companies established in 2005
605:
572:
482:
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332:
304:
1215:
788:
746:
699:
594: ed.). A & C Black.
400:
16:U.K.-based nanopore sequencing company
1223:British companies established in 2005
590:. Vol. 2015 (online edition via
530:Loman, N. J.; Quinlan, A. R. (2014).
475:
267:The company was founded in 2005 as a
1208:Oxford Nanopore Technologies Website
723:"Sequencing DNA in Space - SpaceRef"
581:"BAYLEY, Prof. (John) Hagan (Pryce)"
747:Rainey, Kristine (29 August 2016).
13:
14:
1254:
1201:
674:"No thanks, I've already got one"
613:"DNA sequencing: The hole story"
383:with a range of applications in
245:Oxford Nanopore Technologies plc
217:
216:
197:
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177:
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22:Oxford Nanopore Technologies plc
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993:
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866:
817:
766:
740:
715:
693:
700:Ramsey, Sarah (21 June 2016).
666:
645:
631:
523:
430:
418:. Oxford Nanopore Technologies
1:
548:10.1093/bioinformatics/btu555
394:
1168:Check Hayden, Erika (2012).
599:UK public library membership
7:
489:Molecular Ecology Resources
391:, and scientific research.
328:
323:International Space Station
93:; 19 years ago
10:
1259:
300:Vrije Universiteit Brussel
262:
1228:Companies based in Oxford
1183:10.1038/nature.2012.10051
824:Check Hayden, E. (2015).
810:10.1038/nature.2014.14724
795:Check Hayden, E. (2014).
619:. London. 16 October 2008
251:which develops and sells
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208:
188:
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127:
105:
87:
77:
63:
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35:
26:
592:Oxford University Press
501:10.1111/1755-0998.12324
289:initial public offering
338:
314:
287:. The company made an
224:(154.5) million (2023)
204:(168.7) million (2023)
40:Public limited company
1143:www2.nanoporetech.com
385:personalized medicine
336:
308:
293:London Stock Exchange
165:Gordon Sanghera (CEO)
158:Duncan Tatton-Brown (
440:Nature Biotechnology
273:University of Oxford
184:169.7 million (2023)
880:on 21 November 2015
842:2015Natur.521...15C
453:10.1038/nbt0412-295
309:American astronaut
253:nanopore sequencing
133:Oxford Science Park
82:Nanopore sequencing
23:
1233:Genomics companies
913:10.1038/nmeth.3327
641:. 11 October 2021.
339:
315:
21:
1149:on 23 August 2016
597:(Subscription or
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1145:. Archived from
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1075:nanoporetech.com
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1029:. Archived from
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1003:. Archived from
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542:(23): 3399–401.
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1007:on 27 June 2015
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495:(6): 1097–102.
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381:small molecules
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117:Gordon Sanghera
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1059:. 14 May 2015.
1044:
1033:on 1 June 2016
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907:(4): 303–304.
901:Nature Methods
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970:
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878:the original
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616:
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420:. Retrieved
389:crop science
366:
340:
316:
297:
281:seed funding
277:Hagan Bayley
266:
244:
243:
234:nanoporetech
128:Headquarters
113:Hagan Bayley
71:GB00BP6S8Z30
36:Company type
18:
1114:"Metrichor"
1037:20 November
884:20 November
422:4 September
311:Kate Rubins
1217:Categories
1080:17 October
758:17 October
623:19 October
601:required.)
395:References
211:Net income
151:Key people
1192:1744-7933
1153:17 August
1123:17 August
1071:"VolTRAX"
955:GenomeWeb
921:1548-7091
587:Who's Who
469:205267199
283:from the
271:from the
48:Traded as
1100:Wired UK
929:25825834
860:25951262
566:25143291
509:25187008
461:22491260
377:proteins
329:Products
285:IP Group
269:spin-out
106:Founders
78:Industry
1011:17 June
937:5604121
838:Bibcode
776:bioRxiv
732:25 July
707:25 July
679:YouTube
557:4296151
517:3674911
291:on the
263:History
249:company
229:Website
173:Revenue
96: (
88:Founded
56::
1190:
1174:Nature
985:6 July
960:6 July
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830:Nature
801:Nature
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346:(MAP).
319:SpaceX
137:Oxford
933:S2CID
685:9 May
658:9 May
513:S2CID
465:S2CID
416:(PDF)
357:2016.
353:512).
160:Chair
1188:ISSN
1155:2016
1125:2016
1082:2016
1039:2015
1013:2015
987:2017
962:2017
925:PMID
917:ISSN
886:2015
856:PMID
760:2016
753:NASA
734:2016
709:2016
687:2016
660:2016
625:2014
562:PMID
505:PMID
457:PMID
424:2024
379:and
236:.com
98:2005
91:2005
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1178:doi
909:doi
846:doi
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552:PMC
544:doi
497:doi
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373:RNA
369:DNA
275:by
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
