153:. It is the oldest funding mechanism of the NIH. R01s are generally awarded for 3–5 years, and are used to support a "discrete, specified, circumscribed research project". R01s can be renewed by competitive application. The application cycle has 3 sets of application dates each year. Standard due dates for new grant applications are February, June, and October 5, and for renewal, resubmission, and revision grant applications are March, July, and November 5. AIDs-related grants have separate due dates. All grant-awarding institutes and centers award R01s. Applications for R01s are complex and are typically over 100 pages by submission.
47:), with an overall average of 18%. Funding percentages have dropped from over 30% in the early 2000s, mainly due to an increase in applications, rather than a decrease in funds available. In 1998, 24,100 applications were received, and 7,500 were funded with a total of $ 1.9 billion. By 2005, the number of applications had grown to 43,000, of which 9,600 were funded with a total of $ 3.4 billion. In 2015, 52,000 applications were submitted and 9,500 were funded with $ 4.3 billion. Grants are assessed based on their significance, innovation, and approach.
110:
63:
From 2010 to 2016, NIH funded research that led to the development and approval of 210 new drugs. 84 of these were "first-in-class" drugs, meaning they work through previously unknown mechanisms. About 90% of the research published from the funded grants related to the discovery and characterization
96:
Applications are reviewed by a
Scientific Review Group made up of volunteer subject matter experts, generally professors in the relevant fields, and by a National Advisory Council made up of federal employees. Grants are scored from 1 to 9, with 1 being the highest score. Members of the committees
54:
There are various requirements for grants. Some grants are specified for "new investigators", which is defined as someone who has not received a prior NIH grant other than a career award or specific small grants (R15, R21, R56, etc.). An "early stage investigator" is someone who has received their
50:
The major grant awards of the NIH are divided into
Research Grants (R series), Career Development Awards (K series), Research Training and Fellowships (T & F series), Program Project/Center Grants (P series), and miscellaneous programs.
67:
A study on the value of public research funding found that 30% of NIH grants led to research being published that was cited in a patent application, and that for every $ 100 million funded by the NIH, 23 patents were submitted.
34:
The NIH supports $ 31 billion in research annually, given to more than 300,000 researchers at more than 2,500 institutions for research into a variety of conditions. Each institute of the NIH has separate appropriations from
174:
R15, NIH Academic
Research Enhancement Award (AREA), supports small research projects limited to a total of $ 300k over up to 3 years, at universities in the US that have not received more than $ 6 million from the NIH per
202:
R56, NIH High
Priority, Short-Term Project Award, "bridge grant", funds applications for R01s that did not receive a qualifying score but are compelling. This award cannot be applied for.
28:
188:
156:
In financial year 2016, the NIH received 26,187 applications for new R01 grants. 17.3% were funded, for a total of $ 2.2 billion. The average annual budget was $ 460,000.
86:
Type 3 – Competitive revision of grants currently funded. Investigators can request additional funding for current grants for additional research or unforeseen costs.
178:
R21, NIH Exploratory/Developmental
Research Grant Award, limited to 2 years of funding for a total less than $ 275k, and does not require preliminary data.
554:
44:
92:
Type 5 – Noncompetitive continuation of a current grant. Investigators must submit progress reports to receive continued funding.
688:
40:
83:
Type 2 – Competitive renewal of grants currently funded. Applications are essentially the same as for type 1 applications.
20:
23:(NIH) are the primary government agency responsible for biomedical and public health research. They award
462:
168:
R03, the NIH Small Grant
Program, not renewable and limited to 2 years, with a maximum of $ 50k/year.
590:
487:
39:
determined on an annual basis. Percentages of grant applications funded vary by institute, from 8% (
120:
36:
615:
236:
C06, Research
Construction Programs, for the construction or remodeling of research facilities
437:
646:
518:
8:
16:
Primary government agency responsible for biomedical and public health research in the US
650:
522:
412:
365:
664:
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F30, Individual Ruth L. Kirschstein NRSA for individual MD/PhD Fellows (predoctoral)
654:
526:
390:
197:
572:
531:
506:
682:
261:
R50, Research
Specialist Award, to support the salaries of non-PI scientists
668:
540:
488:"NIH funding contributed to 210 approved drugs in recent years, study says"
463:"Early Stage and Early Established Investigator Policies - grants.nih.gov"
366:"Understand NIH: Finding the Right Fit for Your Research - grants.nih.gov"
181:
R33, Exploratory/Developmental Grants Phase II, available to R21 awardees
109:
338:
K26 Midcareer
Investigator Award in Biomedical and Behavioral Research
320:
K12 Clinical
Scientist Institutional Career Development Program Award
659:
634:
323:
K18 Research Career Enhancement Award for Established Investigators
64:
of these pathways, rather than the development of the drug itself.
317:
K08 Mentored Clinical Scientist Research Career Development Award
347:
K99 Pathway to Independence Award, for postdoctoral researchers
329:
K23 Mentored Patient-Oriented Research Career Development Award
283:
T35, Medical students engaging in a short-term research project
295:
F31, Individual NRSA support for students in doctoral programs
289:
F32, Individual National Research Service Award (postdoctoral)
280:
T34, Undergraduate NRSA Institutional Research Training Grants
233:
RC2, High Impact Research and Research Infrastructure Programs
55:
PhD or MD or has finished residency within the past 10 years.
332:
K24 Midcareer Investigator Award in Patient-Oriented Research
286:
T90, Support for interdisciplinary research training programs
335:
K25 Mentored Quantitative Research Career Development Award
208:
U10, Cooperative Clinical Research Cooperative Agreements
616:"NIH Research Portfolio Online Reporting Tools (RePORT)"
413:"NIH Research Portfolio Online Reporting Tools (RePORT)"
171:
R13, NIH Support for Conferences and Scientific Meetings
308:
K02 Independent Research Scientist Development Award
277:T32, Institutional National Research Service Award
680:
212:
149:The most common research grant mechanism is the
58:
305:K01 Research Scientist Career Development Award
184:R34, NIH Clinical Trial Planning Grant Program
45:National Institute of General Medical Sciences
507:"NIH research grants yield economic windfall"
344:K76 Emerging Leaders Career Development Award
89:Type 4 – Extension of grants currently funded
299:
205:U01, Research Project Cooperative Agreement
591:"Types of Grant Programs - grants.nih.gov"
438:"Types of Grant Programs - grants.nih.gov"
274:T15, Continuing Education Training Program
159:
658:
530:
555:"Types of Applications | grants.nih.gov"
242:DP2, NIH Director's New Innovator Awards
326:K22 Career Transition Development Award
164:Other research grant programs include:
76:NIH numbers the types of applications:
681:
632:
504:
255:R24 Resource-Related Research Projects
71:
41:National Institute of Nursing Research
314:K07 Academic Career Development Award
139:
104:
311:K05 Senior Research Scientist Award
218:P01, Research Program Project Grant
13:
268:
249:
100:
14:
700:
239:DP1, NIH Director's Pioneer Award
227:P41, Biotechnology Resource Grant
633:Dolgin, Elie (1 November 2017).
341:K43 Emerging Global Leader Award
108:
626:
608:
583:
80:Type 1 – New grant applications
573:"Peer Review | grants.nih.gov"
565:
547:
505:Dolgin, Elie (30 March 2017).
498:
480:
455:
430:
405:
383:
358:
189:Outstanding Investigator Award
1:
689:National Institutes of Health
351:
245:DP5, Early Independence Award
213:Program project/center grants
59:Impact on scientific research
21:National Institutes of Health
635:"The young and the restless"
7:
264:X01 Resource Access Program
10:
705:
27:through 24 grant-awarding
19:In the United States, the
532:10.1038/nature.2017.21752
300:Career development awards
230:P50, Specialized Center
224:P30, Center Core Grants
221:P20, Exploratory Grants
193:R36, Dissertation Award
160:Research project grants
258:R25 Education Projects
144:
117:This section is empty.
29:institutes and centers
97:are listed publicly.
651:2017Natur.551S..15D
523:2017Natur.544...14D
494:. 12 February 2018.
72:Application process
140:Funding mechanisms
645:(7678): S15–S18.
393:. 31 October 2014
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128:January 2018
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43:) to 29.6% (
33:
24:
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600:4 December
472:4 December
447:4 December
422:4 December
397:4 December
375:4 December
352:References
25:NIH grants
683:Category
669:29091602
541:28383011
391:"Budget"
37:Congress
647:Bibcode
519:Bibcode
667:
639:Nature
539:
511:Nature
196:R37,
187:R35,
175:year.
665:PMID
602:2017
537:PMID
492:STAT
474:2017
449:2017
424:2017
399:2017
377:2017
655:doi
643:551
527:doi
515:544
151:R01
145:R01
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
