585:(MMWR) noted that most cases of AIDS had been reported among homosexual men with multiple sexual partners, injection drug users, Haitians, and hemophiliacs. The report suggested that AIDS may be caused by an infectious agent that is transmitted sexually or through exposure to blood or blood products, and issued recommendations for preventing transmission. Although most cases of HIV/AIDS were discovered in gay men, on January 7, 1983, the CDC reported cases of AIDS in female sexual partners of males with AIDS. In 1984, scientists identified the virus that causes AIDS, which was first named after the T-cells affected by the strain and is now called HIV or human immunodeficiency virus.
1089:
1102:
252:
98:
557:
1174:, such as traditional medicine, especially in areas where conventional therapies are less widespread. However, the overwhelming majority of scientifically rigorous research indicates little or negative effect on patient outcomes such as HIV-symptom severity and disease duration, and mixed outcomes on psychological well-being. It is important that patients notify their healthcare provider prior to beginning any treatment, as certain alternative therapies may interfere with conventional treatment.
265:
132:(the level of virus in the blood) to low or near-undetectable levels. Disease-specific drugs can also alleviate symptoms of AIDS and even cure specific AIDS-defining conditions in some cases. Medical treatment can reduce HIV infection in many cases to a survivable chronic condition. However, these advances do not constitute a cure, since current treatment regimens cannot eradicate latent HIV from the body.
2636:
831:, albeit modest and short-lived. Among HIV-infected patients who had not yet developed AIDS, placebo-controlled trials found that AZT given as a single-drug therapy delayed, for a year or two, the onset of AIDS-related illnesses. The lack of excess AIDS cases and death in the AZT arms of these placebo-controlled trials effectively counters the argument that AZT causes AIDS.
145:
means if a person living with HIV is well controlled on medications with a viral load less than 200, they cannot transmit HIV to their partners via sexual contact. The landmark study that first established this was the HPTN052 study, which looked at over 2000 couples over 10 years, where one partner was HIV positive, and the other partner was HIV negative.
835:
in progression to AIDS and in survival when compared to two-drug regimens in clinical trials. Use of potent anti-HIV combination therapies has contributed to dramatic reductions in the incidence of AIDS and AIDS-related deaths in populations where these drugs are widely available, an effect which would be unlikely if antiretroviral drugs
1012:
As with many diseases, a number of factors can influence the course of HIV disease. Factors such as age or genetic differences between individuals, the level of virulence of the individual strain of virus, as well as exogenous influences such as co-infection with other microbes may determine the rate
834:
Subsequent clinical trials found that patients receiving two-drug combinations had up to 50% increases in time to progression to AIDS and in survival when compared to people receiving single-drug therapy. In more recent years, three-drug combination therapies have produced another 50–80% improvements
580:
first official reporting of the AIDS epidemic in North
America. By year-end, a cumulative total of 337 cases of severe immune deficiency had been reported, and 130 out of the 337 reported cases had died. On September 24, 1982, the CDC used the term "AIDS" (acquired immune deficiency syndrome) for the
324:
Due to media images of the effects of AIDS, many people believe that individuals infected with HIV always appear a certain way, or at least appear different from an uninfected, healthy person. In fact, disease progression can occur over a long period of time before the onset of symptoms, and as such,
235:
Progress in testing methodology has enabled detection of viral genetic material, antigens, and the virus itself in bodily fluids and cells. While not widely used for routine testing due to high cost and requirements in laboratory equipment, these direct testing techniques have confirmed the validity
231:
tests exceed the performance of most other infectious disease tests in both sensitivity (the ability of the screening test to give a positive finding when the person tested truly has the disease) and specificity (the ability of the test to give a negative finding when the subjects tested are free of
69:
for many years. If undiagnosed or left untreated, HIV usually progresses to AIDS, defined as possessing a CD4+ lymphocyte count under 200 cells/μL or HIV infection plus co-infection with an AIDS-defining opportunistic infection. HIV cannot be cured, but it can be treated, and its transmission can be
981:
estimates that 30 percent of new HIV infections in the United States in 1998 were in women. As the number of HIV-infected women has risen, so too has the number of female AIDS patients in the United States. Approximately 23% of U.S. adult/adolescent AIDS cases reported to the CDC in 1998 were among
969:
men. HIV is spread primarily through unprotected sex, the exchange of HIV-contaminated needles, or cross-contamination of the drug solution and infected blood during intravenous drug use. Because these behaviors show a gender skew—Western men are more likely to take illegal drugs intravenously than
507:
Although the fraction of CD4+ T-cells that is infected with HIV at any given time is never high (only a small subset of activated cells serve as ideal targets of infection), several groups have shown that rapid cycles of death of infected cells and infection of new target cells occur throughout the
386:
HIV can survive at room temperature outside the body for hours if dry (provided that initial concentrations are high), and for weeks if wet (in used syringes/needles). However, the amounts typically present in bodily fluids do not survive nearly as long outside the body—generally no more than a few
377:
and can infect a bitten person with these diseases. HIV is not transmitted in this manner. On the other hand, a mosquito may have HIV-infected blood in its gut, and if swatted on the skin of a human who then scratches it, transmission is hypothetically possible, though this risk is extremely small,
199:
is a means to avoid AIDS or cure it if infected. As with "virgin cure" beliefs, there is no scientific evidence suggesting a sexual act can actually cure AIDS, and no plausible mechanism by which it could do so has ever been proposed. While the risk of contracting HIV via sex with animals is likely
144:
reduces the chance of acquiring an HIV infection when administered within 72 hours of exposure to HIV. However, an overwhelming body of clinical evidence has demonstrated the U=U rule - if someone's viral load is undetectable (<200 viral copies per mL) they are untransmissible. Essentially this
793:
of HIV disease, even though important details remain to be elucidated. However, a complete understanding of the pathogenesis of a disease is not a prerequisite to knowing its cause. Most infectious agents have been associated with the disease they cause long before their pathogenic mechanisms have
951:
Among HIV-infected hemophiliacs, Transfusion Safety Study investigators found that neither the purity nor the amount of factor VIII therapy had a deleterious effect on CD4+ T-cell counts. Similarly, the
Multicenter Hemophilia Cohort Study found no association between the cumulative dose of plasma
947:
with 17 HIV-seronegative hemophiliacs with regard to clotting factor concentrate usage over a ten-year period. During this time, 16 AIDS-defining clinical events occurred in 9 patients, all of whom were HIV-seropositive. No AIDS-defining illnesses occurred among the HIV-negative patients. In each
922:
for similar diseases. Approximately 3 years following blood transfusion, the mean CD4+ T-cell count in 64 HIV-negative recipients was 850/μL of blood, while 111 HIV-seropositive individuals had average CD4+ T-cell counts of 375/μL of blood. By 1993, there were 37 cases of AIDS in the HIV-infected
1412:
Eshleman, Susan H.; Wilson, Ethan A.; Zhang, Xinyi C.; Ou, San-San; Piwowar-Manning, Estelle; Eron, Joseph J.; McCauley, Marybeth; Gamble, Theresa; Gallant, Joel E.; Hosseinipour, Mina C.; Kumarasamy, Nagalingeswaran; Hakim, James G.; Kalonga, Ben; Pilotto, Jose H.; Grinsztejn, Beatriz; Godbole,
935:
enrolled in the
Transfusion Safety Study, no significant differences in CD4+ T-cell counts were noted between 79 patients with no or minimal factor treatment and 52 with the largest amount of lifetime treatments. Patients in both groups had CD4+ T-cell-counts within the normal range. In another
413:, while for women transmission is primarily through heterosexual contact. It is true that anal sex (regardless of the sex of the receptive partner) carries a higher risk of infection than most sex acts, but most penetrative sex acts between any individuals carry some risk. Properly used
232:
the disease under study). Many current HIV antibody tests have sensitivity and specificity in excess of 96% and are therefore extremely reliable. While most patients with HIV show an antibody response after six weeks, window periods vary and may occasionally be as long as three months.
655:" of the HIV/AIDS epidemic, meaning the first case of HIV/AIDS in the United States. In fact, the "patient zero" moniker originated from a misinterpretation of a 1984 study that referred to Dugas as "patient O", where the O stood for "out of California". A 2016 study published in
3149:
Taha, T.E.; Kumwenda, N.I.; Broadhead, R.L.; Hoover, D.R.; Graham, S.M.; Van Der, Hoven L.; Markakis, D.; Liomba, G.N.; Chiphangwi, J.D.; et al. (1999). "Mortality after the first year of life among human immunodeficiency virus type 1-infected and uninfected children".
3774:
Donegan, E.; Stuart, M.; Niland, J.C.; Sacks, H.S.; Azen, S.P.; Dietrich, S.L.; Faucett, C.; Fletcher, M.A.; Kleinman, S.H.; et al. (1990). "Infection with human immunodeficiency virus type 1 (HIV-1) among recipients of antibody-positive blood donations".
272:
One cannot become infected with HIV through normal contact in social settings, schools, or in the workplace. Other examples of casual contact in which HIV infection will not occur include shaking someone's hand, hugging or "dry" kissing someone, using the same
581:
first time, and released the first case definition of AIDS: "a disease at least moderately predictive of a defect in cell-mediated immunity, occurring in a person with no known case for diminished resistance to that disease." The March 4, 1983 edition of the
619:
for food, and epidemiologists theorize that the disease may have appeared in humans after hunters came into blood-contact with monkeys infected with SIV that they had killed. The first known instance of HIV in a human was found in a person who died in the
3105:
Ackah, A.N.; Coulibaly, D.; Digbeu, H.; Diallo, K.; Vetter, K.M.; Coulibaly, I.M.; Greenberg, A.E.; De Cock, K.M. (1995). "Response to treatment, mortality, and CD4 lymphocyte counts in HIV-infected persons with tuberculosis in
Abidjan, Cote d'Ivoire".
1758:
Urassa, W.; Godoy, K.; Killewo, J.; Kwesigabo, G.; Mbakileki, A.; Mhalu, F.; Biberfeld, G. (1999). "The accuracy of an alternative confirmatory strategy for detection of antibodies to HIV-1: experience from a regional laboratory in Kagera, Tanzania".
4025:
Goedert, JJ; Kessler, CM; Aledort, LM; Biggar, RJ; Andes, WA; White Gc, 2nd; Drummond, JE; Vaidya, K; et al. (1989). "A prospective study of human immunodeficiency virus type 1 infection and the development of AIDS in subjects with hemophilia".
3275:
Mocroft, A.; Vella, S.; Benfield, T.L.; Chiesi, A.; Miller, V.; Gargalianos, P.; Arminio
Monforte, A.; Yust, I.; Bruun, J.N.; et al. (1998). "Changing patterns of mortality across Europe in patients infected with HIV-1. EuroSIDA Study Group".
735:
and who survived the first year of life was 9.5 times higher among HIV-seropositive children than among HIV-seronegative children. The leading causes of death were wasting and respiratory conditions. Elsewhere in Africa, findings are similar.
872:, 715 homosexual men were followed for a median of 8.6 years. Among 365 HIV-positive individuals, 136 developed AIDS. No AIDS-defining illnesses occurred among 350 seronegative men, despite the fact that these men reported appreciable use of
39:
arise from several different sources, from simple ignorance and misunderstandings about scientific knowledge regarding HIV infections and the cause of AIDS to misinformation propagated by individuals and groups with ideological stances that
2177:
Webb, P.A.; Happ, C.M.; Maupin, G.O.; Johnson, B.J.; Ou, C.Y.; Monath, T.P. (1989). "Potential for insect transmission of HIV: experimental exposure of Cimex hemipterus and
Toxorhynchites amboinensis to human immunodeficiency virus".
65:). Contracting HIV can lead to the development of AIDS or stage 3 HIV, which causes serious damage to the immune system. While this virus is the underlying cause of AIDS, not all HIV-positive individuals have AIDS, as HIV can remain
1466:
906:, mean CD4+ T-cell counts of the group were consistently more than 1000 cells/μL of blood. Only two individuals had two CD4+ T-cell measurements of less than 300/μL of blood, one of whom died with cardiac disease and
895:, more than 22,000 T-cell determinations in 2,713 HIV-seronegative homosexual men revealed only one individual with a CD4+ T-cell count persistently lower than 300 cells/μL of blood, and this individual was receiving
4668:
1413:
Sheela V.; Chotirosniramit, Nuntisa; Santos, Breno Riegel; Shava, Emily; Mills, Lisa A.; Panchia, Ravindre; Mwelase, Noluthando; Mayer, Kenneth H.; Chen, Ying Q.; Cohen, Myron S.; Fogel, Jessica M. (May 2017).
1838:
Samdal, H.H.; Gutigard, B.G.; Labay, D.; Wiik, S.I.; Skaug, K.; Skar, A.G. (1996). "Comparison of the sensitivity of four rapid assays for the detection of antibodies to HIV-1/HIV-2 during seroconversion".
1128:(MAC), are not caused by HIV, but rather result from the immunosuppression caused by HIV disease. As the immune system of an HIV-infected individual weakens, he or she becomes susceptible to the particular
960:
The distribution of AIDS cases, whether in the United States or elsewhere in the world, invariably mirrors the prevalence of HIV in a population. In the United States, HIV first appeared in populations of
163:-infected person, and such contact will expose the uninfected individual to HIV, potentially further spreading the disease. This myth has gained considerable notoriety as the perceived reason for certain
297:(CDC) has only recorded one case of possible HIV transmission through kissing (involving an HIV-infected man with significant gum disease and a sexual partner also with significant gum disease), and the
135:
High levels of HIV-1 (often HAART-resistant) develop if treatment is stopped, if compliance with treatment is inconsistent, or if the virus spontaneously develops resistance to an individual's regimen.
289:
carries a negligible viral load, so even open-mouthed kissing is considered a low risk. However, if the infected partner or both of the performers have blood in their mouth due to cuts, open sores, or
3446:"Reduction in mortality with availability of antiretroviral therapy for children with perinatal HIV-1 infection. Italian Register for HIV Infection in Children and the Italian National AIDS Registry"
1152:, which is caused by a fungus. A person in Africa is exposed to pathogens different from individuals in an American city. Children may be exposed to different infectious agents compared to adults.
989:, and AIDS cases in Africa have occurred at least as frequently in women as in men. Overall, the worldwide distribution of HIV infection and AIDS between men and women is approximately 1 to 1. In
3747:
Des
Jarlais, D.C.; Friedman, S.R.; Marmor, M.; Mildvan, D.; Yancovitz, S.; Sotheran, J.L.; Wenston, J.; Beatrice, S. (1993). "CD4 lymphocytopenia among injecting drug users in New York City".
982:
women. In 1998, AIDS was the fifth leading cause of death among women aged 25 to 44 in the United States, and the third leading cause of death among
African-American women in that age group.
3319:
Mocroft, A.; Katlama, C.; Johnson, A.M.; Pradier, C.; Antunes, F.; Mulcahy, F.; Chiesi, A.; Phillips, A.N.; Kirk, O.; et al. (2000). "AIDS across Europe, 1994–98: the EuroSIDA study".
4663:
3986:"Effect of low- and intermediate-purity clotting factor therapy on progression of human immunodeficiency virus infection in congenital clotting disorders. Transfusion Safety Study Group"
4293:
Littlewood, RA; Vanable, PA (8 Dec 2011). "A global perspective on complementary and alternative medicine use among people living with HIV/AIDS in the era of antiretroviral treatment".
3663:
Schechter, M.T.; Craib, K.J.; Gelmon, K.A.; Montaner, J.S.; Le, T.N.; O'Shaughnessy, M.V.; Schechter, M.T.; Gelmon, K.A.; Montaner, J.S.G. (1993). "HIV-1 and the aetiology of AIDS".
1001:
HIV infections have a prolonged and variable course. The median period of time between infection with HIV and the onset of clinically apparent disease is approximately 10 years in
1974:
1474:
429:. Normally, the risk of transmitting HIV to the unborn child is between 15 and 30%. However, this may be reduced to just 2–3% if patients carefully follow medical guidelines.
480:
may be activated after years of latency even in the presence of abundant antibodies. In other animals, viral relatives of HIV with long and variable latency periods, such as
4975:
955:
977:
Women in the United States, however, are increasingly becoming HIV-infected, usually through the exchange of HIV-contaminated needles or sex with an HIV-infected male. The
1723:
Silvester, C.; Healey, D.S.; Cunningham, P.; Dax, E.M. (1995). "Multisite evaluation of four anti-HIV-1/HIV-2 enzyme immunoassays. Australian HIV Test
Evaluation Group".
4939:
2256:
Resnick, L.; Veren, K.; Salahuddin, S.Z.; Tondreau, S.; Markham, P.D. (1986). "Stability and inactivation of HTLV-III/LAV under clinical and laboratory environments".
918:
This notion is contradicted by a report by the
Transfusion Safety Study Group (TSSG), which compared HIV-negative and HIV-positive blood recipients who had been given
568:
in the early 1960s, or from another person who worked there during that time. In 1981 on June 5, the U.S. Centers for Disease Control and Prevention (CDC) published a
3855:"Effect on lymphocyte subsets of clotting factor therapy in human immunodeficiency virus-1-negative congenital clotting disorders. The Transfusion Safety Study Group"
794:
been discovered. Because research in pathogenesis is difficult when precise animal models are unavailable, the disease-causing mechanisms in many diseases, including
936:
report from the Transfusion Safety Study, no instances of AIDS-defining illnesses were seen among 402 HIV-seronegative hemophiliacs who had received factortherapy.
4658:
3610:"Effects of antiretroviral therapy and opportunistic illness primary chemoprophylaxis on survival after AIDS diagnosis. Adult/Adolescent Spectrum of Disease Group"
2931:
5030:
3405:"Effectiveness of potent antiretroviral therapy on time to AIDS and death in men with known HIV infection duration. Multicenter AIDS Cohort Study Investigators"
1009:
are known. Similar estimates of asymptomatic periods have been made for HIV-infected blood-transfusion recipients, injection-drug users and adult hemophiliacs.
44:
a causative relationship between HIV infection and the development of AIDS. Below is a list and explanations of some common misconceptions and their rebuttals.
5626:
3187:
2956:
Auerbach, D.M.; W.W. Darrow; H.W. Jaffe; J.W. Curran (1984). "Cluster of cases of the acquired immune deficiency syndrome. Patients linked by sexual contact".
2413:
1586:
1291:
312:
and home health care procedures, yet there are very few recorded incidents of transmission occurring in these ways. A handful of cases of transmission via
3569:"Epidemiology of human immunodeficiency virus-associated opportunistic infections in the United States in the era of highly active antiretroviral therapy"
3528:"Impact of protease inhibitors and other antiretroviral treatments on acquired immunodeficiency syndrome survival in San Francisco, California, 1987–1996"
956:
The distribution of AIDS cases casts doubt on HIV as the cause. Viruses are not gender-specific, yet only a small proportion of AIDS cases are among women
883:
Other studies show that among homosexual men and injection-drug users, the specific immune deficit that leads to AIDS—a progressive and sustained loss of
5621:
4675:
200:
much lower than with humans due to HIV's inability to infect animals, the practice of bestiality still has the ability to infect humans with other fatal
4428:
Piscitelli, Stephen C; Burstein, Aaron H; Chaitt, Doreen; Alfaro, Raul; Falloon, Judith (14 April 2001). "Indinavir concentrations and St John's wort".
409:
HIV can transmit from one person to another if an engaging partner is HIV positive. In the United States, the main route of infection is via homosexual
1633:
Jackson, J.B.; Kwok, S.Y.; Sninsky, J.J.; Hopsicker, J.S.; Sannerud, K.J.; Rhame, F.S.; Henry, K.; Simpson, M.; Balfour, H.H. Jr; et al. (1990).
1083:
1342:
Becker, S.; Dezii, C.M.; Burtcel, B.; Kawabata, H.; Hodder, S. (2002). "Young HIV-infected adults are at greater risk for medication nonadherence".
5136:
4117:
184:
2412:"Disease Progression Despite Antibodies", "The Relationship Between the Human Immunodeficiency Virus and the Acquired Immunodeficiency Syndrome",
2318:
4609:
4061:
2892:
1917:
Courville, T.M.; Caldwell, B.; Brunell, P.A. (1998). "Lack of evidence of transmission of HIV-1 to family contacts of HIV-1 infected children".
3853:
Hassett, J.; Gjerset, G.F.; Mosley, J.W.; Fletcher, M.A.; Donegan, E.; Parker, J.W.; Counts, R.B.; Aledort, L.M.; Lee, H.; et al. (1993).
2907:
1259:
1155:
HIV is the underlying cause of the condition named AIDS, but the additional conditions that may affect an AIDS patient are dependent upon the
5010:
3984:
Gjerset, G.F.; Pike, M.C.; Mosley, J.W.; Hassett, J.; Fletcher, M.A.; Donegan, E.; Parker, J.W.; Counts, R.B.; Zhou, Y.; et al. (1994).
1682:
Busch, M.P.; Eble, B.E.; Khayam-Bashi, H.; Heilbron, D.; Murphy, E.L.; Kwok, S.; Sninsky, J.; Perkins, H.A.; Vyas, G.N.; et al. (1991).
2535:
Xu, X.N.; Laffert, B.; Screaton, G.R.; Kraft, M.; Wolf, D.; Kolanus, W.; Mongkolsapay, J.; McMichael, A.J.; Baur, A.S.; et al. (1999).
816:
The vast majority of people with AIDS never received antiretroviral drugs, including those in developed countries prior to the licensure of
515:
Furthermore, like other viruses, HIV is able to suppress the immune system by secreting proteins that interfere with it. For example, HIV's
3236:"Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators"
1684:"Evaluation of screened blood donations for human immunodeficiency virus type 1 infection by culture and DNA amplification of pooled cells"
4882:
4701:
4651:
4599:
2680:"Cross-species transmission of simian retroviruses: how and why they could lead to the emergence of new diseases in the human population"
542:. This "bystander killing" effect shows that great harm can be caused to the immune system even with a limited number of infected cells.
3016:
913:
4995:
4524:
2348:
978:
851:, have existed for many years. The epidemic of AIDS, characterized by the occurrence of formerly rare opportunistic infections such as
294:
1399:"HIV Undetectable=Untransmittable (U=U), or Treatment as Prevention | NIH: National Institute of Allergy and Infectious Diseases"
868:
men for long periods of time and found that only HIV-seropositive men develop AIDS. For example, in a prospectively studied cohort in
864:
Compelling evidence against the hypothesis that behavioral factors cause AIDS comes from recent studies that have followed cohorts of
357:
bite a person, they do not inject the blood of a previous victim into the person they bite next. Mosquitoes do, however, inject their
1978:
527:
receptors of otherwise healthy T-cells; this interferes with the normal function of these signalling receptors. Another HIV protein,
1036:
4809:
4336:
Mills, Edward; Wu, Ping; Ernst, Edzard (June 2005). "Complementary therapies for the treatment of HIV: in search of the evidence".
3203:
2396:
1287:
993:, 57% of adults with HIV are women, and young women aged 15 to 24 are more than three times as likely to be infected as young men.
2047:"Teaching Taboo Topics Without Talking About Them: An Epistemic Study of a New Approach to HIV/AIDS Prevention Education in India"
1084:
The spectrum of AIDS-related infections seen in different populations proves that AIDS is actually many diseases not caused by HIV
637:
was the subject of controversy in 2012 after stating that AIDS was the result of a human having sexual intercourse with a monkey.
1193:
3608:
McNaghten, A.D.; Hanson, D.L.; Jones, J.L.; Dworkin, M.S.; Ward, J.W.; The Adultadolescent Spectrum Of Disease Group +/ (1999).
3234:
Palella, F.J. Jr; Delaney, K.M.; Moorman, A.C.; Loveless, M.O.; Fuhrer, J.; Satten, G.A.; Aschman, D.J.; Holmberg, S.D. (1998).
564:
The current consensus is that HIV was introduced to North America by a Haitian immigrant who contracted it while working in the
4721:
4551:
3894:
Aledort, L.M.; Operskalski, E.A.; Dietrich, S.L.; Koerper, M.A.; Gjerset, G.F.; Lusher, J.M.; Lian, E.C.; Mosley, J.W. (1993).
2994:
1080:
evidence shows a very large rise in cases of immunosuppression among individuals who share one characteristic: HIV infection.
926:
4970:
1382:
121:
2291:
Heimer, R.; Abdala, N. (2000). "Viability of HIV-1 in syringes: implications for interventions among injection drug users".
159:
The myth that sex with a virgin will cure AIDS is prevalent in South Africa. Sex with an uninfected virgin does not cure an
5401:
31:(WHO) estimated that in 2016 there were 36.7 million people worldwide living with HIV/AIDS, with 1.8 million new
1313:
5089:
842:
4381:"Complementary and alternative medicine use among HIV-positive people: research synthesis and implications for HIV care"
1076:
and certain kinds of cancers. There is no evidence suggesting that the numbers of such cases have risen, while abundant
5526:
4766:
3403:
Detels, R.; Munoz, A.; McFarlane, G.; Kingsley, L.A.; Margolick, J.B.; Giorgi, J.; Schrager, L.K.; Phair, J.P. (1998).
948:
pair, the mean CD4+ T-cell count during follow-up was, on average, 500 cells/μL lower in the HIV-seropositive patient.
528:
62:
1797:; Maurice, C.; Koblavi, S.; Kalou, M.; Yavo, D.; Maran, M.; Bile, C.; N'guessan, K.; Kouadio, J.; et al. (1999).
432:
4949:
4839:
3937:"Comparison of immunodeficiency and AIDS defining conditions in HIV negative and HIV positive men with haemophilia A"
970:
Western women, and men are more likely to report higher levels of the riskiest sexual behaviors, such as unprotected
914:
AIDS among transfusion recipients is due to underlying diseases that necessitated the transfusion, rather than to HIV
727:
were 17 times more likely to die within six months than HIV-seronegative individuals with pulmonary tuberculosis. In
661:
found "neither biological nor historical evidence that was the primary case in the US or for subtype B as a whole."
425:
HIV-infected women remain fertile, although in late stages of HIV disease a pregnant woman may have a higher risk of
3184:
1541:
Groce, N.E.; Trasi, R. (2004). "Rape of individuals with disability: AIDS and the folk belief of virgin cleansing".
827:
enrolling patients with AIDS found that AZT given as single-drug therapy conferred a survival advantage compared to
560:
The cover page of MMWR on July 3, 1981. The first major public info regarding (what later became known as) AIDS/HIV.
4696:
2958:
2908:"Stacey Campfield, Tennessee Senator Behind 'Don't Say Gay' Bill, On Bullying, AIDS And Homosexual 'Glorification'"
621:
565:
1583:
502:
4148:
Alcabes, P.; Munoz, A.; Vlahov, D.; Friedland, G.H. (1993). "Incubation period of human immunodeficiency virus".
1115:
1092:
1037:
HIV is not the cause of AIDS because some people have symptoms associated with AIDS but are not infected with HIV
5429:
4691:
2537:"Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain"
2120:
Patel, Pragna; Borkowf, Craig B.; Brooks, John T.; Lasry, Arielle; Lansky, Amy; Mermin, Jonathan (2014-06-19).
101:
A bottle containing Stribild tablets (medication used to treat HIV). Stribild is a combination drug containing
1602:
624:
in 1959, and a recent study dates the last common ancestor of HIV and SIV to between 1884 and 1914 by using a
404:
5491:
4985:
4716:
4604:
3567:
Kaplan, JE; Hanson, D; Dworkin, MS; Frederick, T; Bertolli, J; Lindegren, ML; Holmberg, S; Jones, JL (2000).
2654:
892:
600:
396:
102:
5604:
4877:
4865:
4746:
4706:
1635:"Human immunodeficiency virus type 1 detected in all seropositive symptomatic and asymptomatic individuals"
927:
High usage of clotting factor concentrate, not HIV, leads to CD4+ T-cell depletion and AIDS in hemophiliacs
58:
3485:
Hogg, R.S.; Yip, B.; Kully, C.; Craib, K.J.; O'Shaughnessy, M.V.; Schechter, M.T.; Montaner, J.S. (1999).
2073:"Mucosal HIV transmission and vaccination strategies through oral compared with vaginal and rectal routes"
345:. No cases of such a transmission were observed in a sample of 8965 people performing receptive oral sex.
5657:
5376:
5072:
5000:
4929:
4887:
4631:
4589:
1874:
Madhok, R.; Gracie, J.A.; Lowe, G.D.; Forbes, C.D. (1986). "Lack of HIV transmission by casual contact".
1122:
1105:
996:
869:
4471:
Piscitelli, Stephen; Burstein, Aaron H.; Weldon, Nada; Gallicano, Keith D.; Falloon, Judith (Jan 2002).
4124:
2618:
2322:
572:(MMWR) describing cases of a rare lung infection, Pneumocystis carinii pneumonia (PCP), in five healthy
5066:
4990:
4980:
4711:
4544:
3487:"Improved survival among HIV-infected patients after initiation of triple-drug antiretroviral regimens"
2046:
1183:
679:
843:
Behavioral factors such as recreational drug use and multiple sexual partners—not HIV—account for AIDS
5540:
5508:
5496:
5449:
5025:
1398:
907:
896:
141:
28:
820:
in 1987. Even today, very few individuals in developing countries have access to these medications.
5381:
5231:
5104:
4792:
4751:
1141:
1002:
670:
433:
HIV cannot be the cause of AIDS because the body develops a vigorous antibody response to the virus
137:
124:(HAART) in many cases allows the stabilization of the patient's symptoms, partial recovery of CD4+
1498:
Meel, B.L. (2003). "1. The myth of child rape as a cure for HIV/AIDS in Transkei: a case report".
538:, a cell-surface protein that triggers the death of neighboring uninfected T-cells expressing the
342:
5647:
5599:
5471:
5346:
5264:
5166:
4731:
4726:
1042:
71:
3362:
Vittinghoff, E.; Scheer, S.; O'Malley, P.; Colfax, G.; Holmberg, S.D.; Buchbinder, S.P. (1999).
5311:
5284:
5274:
5196:
5181:
5079:
4899:
4829:
4636:
4626:
1198:
1156:
1088:
754:
that HIV is the cause of AIDS, but some individuals reject this consensus, including biologist
724:
503:
Only a small number of CD4+ T-cells are infected by HIV, not enough to damage the immune system
489:
92:
1799:"Evaluation of HIV serial and parallel serologic testing algorithms in Abidjan, Cote d'Ivoire"
923:
group, but not a single AIDS-defining illness in the HIV-seronegative transfusion recipients.
5594:
5548:
5486:
5476:
5386:
5321:
4892:
4860:
4797:
4621:
4537:
4279:
4055:
2886:
931:
This view is contradicted by many studies. For example, among HIV-seronegative patients with
891:—is extremely rare in the absence of other immunosuppressive conditions. For example, in the
848:
779:
298:
154:
1314:"Children and HIV and AIDS – What is the relationship between HIV and AIDS and emergencies?"
5563:
5481:
5396:
5371:
5356:
5294:
5246:
5226:
5151:
5146:
5131:
4872:
4804:
4237:
3819:
3049:
2932:"Knoxville Republican says AIDS came from man having sex with a monkey then with other men"
2848:
2834:
2789:
2442:
2222:
1171:
1101:
853:
751:
468:
259:
243:, viral genetic material and the virus itself, providing confirmation of actual infection.
4161:
3444:
De Martino, M; Tovo, PA; Balducci, M; Galli, L; Gabiano, C; Rezza, G; Pezzotti, P (2000).
1029:
and hepatocellular carcinoma. Co-factors probably also determine why some smokers develop
8:
5578:
5553:
5521:
5439:
5411:
5361:
5279:
5269:
5221:
5211:
5201:
5176:
4787:
4761:
2370:
Groginsky, E.; Bowdler, N.; Yankowitz, J. (1998). "Update on vertical HIV transmission".
2053:
811:
4241:
3823:
3649:
3364:"Combination antiretroviral therapy and recent declines in AIDS incidence and mortality"
3210:
3053:
3036:"1970s and 'Patient 0' HIV-1 genomes illuminate early HIV/AIDS history in North America"
2852:
2793:
2446:
2226:
2019:
2000:
1068:
can have increased susceptibility to unusual infections, as do individuals with certain
716:
5568:
5558:
5466:
5461:
5434:
5421:
5406:
5391:
5341:
5304:
5289:
5241:
5236:
5216:
5186:
5161:
5121:
5113:
5045:
5040:
4909:
4834:
4736:
4453:
4405:
4380:
4361:
4318:
4261:
4201:
4184:
3961:
3936:
3688:
3503:
3486:
3344:
3301:
3131:
3070:
3035:
2869:
2815:
2753:
2728:
2709:
2561:
2536:
2454:
2154:
2121:
2097:
2072:
1942:
1899:
1566:
1523:
1439:
1414:
1065:
990:
919:
847:
The proposed behavioral causes of AIDS, such as multiple sexual partners and long-term
775:
771:
512:
and other cell types are also infected with HIV and serve as reservoirs for the virus.
446:
168:
4441:
3896:"Low CD4+ counts in a study of transfusion safety. The Transfusion Safety Study Group"
3332:
3289:
3119:
2512:
2487:
2463:
2430:
1887:
1852:
1772:
1659:
1634:
1554:
997:
HIV is not the cause of AIDS because many individuals with HIV have not developed AIDS
5652:
5516:
5366:
5336:
5316:
5299:
5206:
5171:
5156:
5141:
5126:
4904:
4814:
4771:
4641:
4494:
4445:
4410:
4353:
4310:
4253:
4206:
4165:
4043:
4007:
3966:
3917:
3876:
3835:
3792:
3756:
3729:
3680:
3676:
3631:
3626:
3609:
3590:
3549:
3508:
3467:
3426:
3385:
3336:
3293:
3257:
3167:
3163:
3123:
3075:
3033:
2975:
2971:
2874:
2807:
2778:"An African HIV-1 sequence from 1959 and implications for the origin of the epidemic"
2758:
2701:
2566:
2517:
2468:
2379:
2300:
2273:
2238:
2195:
2159:
2141:
2102:
2024:
1934:
1891:
1856:
1820:
1815:
1798:
1776:
1740:
1736:
1705:
1664:
1558:
1515:
1444:
1378:
1371:
1351:
1241:
1236:
1219:
1050:
873:
857:
pneumonia (PCP), did not occur in the United States until a previously unknown human
778:. (Some one-time skeptics have since rejected AIDS denialism, including physiologist
212:
201:
4322:
4089:
3692:
3305:
3135:
2713:
2344:
1946:
1903:
1570:
680:
There is no AIDS in Africa, as AIDS is nothing more than a new name for old diseases
5573:
5351:
5331:
5326:
5256:
5191:
4934:
4484:
4457:
4437:
4400:
4392:
4365:
4345:
4302:
4265:
4245:
4196:
4157:
4103:
4075:
4035:
3997:
3956:
3948:
3935:
Sabin, C.A.; Pasi, K.J.; Phillips, A.N.; Lilley, P.; Bofill, M.; Lee, C.A. (1996).
3907:
3866:
3827:
3784:
3719:
3672:
3621:
3580:
3539:
3498:
3457:
3416:
3375:
3348:
3328:
3285:
3247:
3159:
3115:
3065:
3057:
3040:
2967:
2864:
2856:
2839:
2819:
2797:
2748:
2740:
2691:
2556:
2548:
2507:
2499:
2458:
2450:
2265:
2230:
2187:
2149:
2133:
2092:
2084:
2014:
1926:
1883:
1848:
1810:
1768:
1732:
1695:
1654:
1646:
1550:
1527:
1507:
1434:
1426:
1231:
1165:
1061:
971:
877:
783:
731:, mortality over three years among children who had received recommended childhood
657:
634:
631:
604:
476:
4002:
3985:
3871:
3854:
1430:
802:, are poorly understood, but the pathogens responsible are very well established.
251:
5084:
4824:
4594:
3788:
3191:
2696:
2679:
2137:
2088:
1794:
1590:
1056:
However, immunosuppression has many other potential causes. Individuals who take
625:
607:, highly plausible explanations for the transfer of the disease between species (
463:
374:
97:
4039:
3912:
3895:
3724:
3707:
3252:
3235:
2776:
Zhu, T.; Korber, B.T.; Nahmias, A.J.; Hooper, E.; Sharp, P.M.; Ho, D.D. (1998).
2744:
2584:
1700:
1683:
1650:
646:
615:. In particular, the African chimpanzees and monkeys which carry SIV are often
556:
400:
277:
or drinking from the same glass as an HIV-infected person, and being exposed to
5035:
4819:
3708:"CD4+ counts in seronegative homosexual men. The Multicenter AIDS Cohort Study"
2191:
2005:
1930:
1321:
1149:
1057:
1006:
974:—it is not surprising that a majority of U.S. AIDS cases have occurred in men.
962:
940:
824:
755:
745:
685:
674:
551:
457:
cells, eventually causing a chronic neurologic disease despite the presence of
319:
41:
4396:
4306:
1962:
1614:
Gilbert, Mark; Krajden, Mel (July–August 2010). "Don't wait to test for HIV".
88:
5641:
5015:
4924:
4349:
3952:
3810:
Cohen, J. (1994). "Duesberg and critics agree: hemophilia is the best test".
3421:
3404:
2640:
2269:
2145:
1145:
1077:
1013:
and severity of HIV disease expression. Similarly, some people infected with
903:
759:
239:
Positive HIV antibody tests are usually followed up by retests and tests for
106:
4520:
3831:
3544:
3527:
2234:
1140:
infections common in the community. For example, HIV-infected people in the
1021:
and clear their infection, while others suffer disease ranging from chronic
178:
66:
5050:
4741:
4498:
4449:
4414:
4357:
4314:
3635:
3594:
3553:
3512:
3471:
3462:
3445:
3340:
3171:
3079:
2878:
2762:
2705:
2570:
2552:
2521:
2304:
2163:
2106:
2028:
1824:
1780:
1562:
1519:
1511:
1448:
1355:
1245:
1073:
986:
932:
795:
790:
763:
732:
720:
709:
693:
594:
539:
370:
362:
192:
188:
172:
164:
110:
4257:
4210:
4169:
4047:
4011:
3970:
3921:
3880:
3839:
3796:
3760:
3733:
3684:
3430:
3389:
3297:
3261:
3127:
2979:
2811:
2472:
2383:
2277:
2242:
2199:
1938:
1895:
1860:
1744:
1709:
1668:
1603:"HIV Assays: Operational Characteristics", World Health Organization, 2004
805:
4954:
4855:
4646:
2042:
1030:
1014:
944:
799:
767:
588:
481:
426:
290:
4473:"The Effect of Garlic Supplements on the Pharmacokinetics of Saquinavir"
3061:
2955:
2860:
260:
HIV can be spread through casual contact with an HIV infected individual
4914:
4756:
4584:
1005:, according to prospective studies of homosexual men in which dates of
865:
858:
817:
705:
701:
652:
612:
535:
509:
458:
442:
309:
114:
381:
4249:
2835:"Direct evidence of extensive diversity of HIV-1 in Kinshasa by 1960"
2057:
1159:
1026:
216:
196:
4225:
2503:
2488:"Normal physiology and HIV pathophysiology of human T-cell dynamics"
651:
The Canadian flight attendant Gaëtan Dugas has been referred to as "
390:
5020:
4919:
4616:
4564:
4489:
4472:
3585:
3568:
3380:
3363:
3361:
3034:
Worobey, Michael; Thomas D. Watts; et al. (October 26, 2016).
1368:
1188:
1137:
1069:
1018:
952:
concentrate and incidence of AIDS among HIV-infected hemophiliacs.
689:
608:
410:
354:
338:
334:
282:
278:
264:
228:
224:
24:
20:
4529:
2802:
2777:
148:
4944:
3893:
2639:
This article incorporates text from this source, which is in the
876:("poppers") and other recreational drugs, and frequent receptive
828:
616:
573:
450:
366:
240:
129:
3746:
2833:
Worobey, Michael; Gemmel, Marlea; et al. (2 October 2008).
2319:"HIV Surveillance –Epidemiology of HIV Infection (through 2008)"
1415:"Virologic outcomes in early antiretroviral treatment: HPTN 052"
1166:
AIDS can be prevented with complementary or alternative medicine
23:
has affected millions of people worldwide; AIDS is considered a
5060:
3526:
Schwarcz, S.K.; Hsu, L.C.; Vittinghoff, E.; Katz, M.H. (2000).
2122:"Estimating per-act HIV transmission risk: a systematic review"
1133:
1046:
888:
728:
516:
496:
414:
358:
313:
286:
274:
125:
2255:
420:
4976:
European and Developing Countries Clinical Trials Partnership
3233:
1793:
1681:
1129:
1022:
697:
520:
485:
454:
438:
328:
220:
3852:
3662:
3566:
3402:
3318:
2832:
1722:
902:
In a survey of 229 HIV-seronegative injection-drug users in
696:
have long been severe burdens there. However, high rates of
320:
HIV-positive individuals can be detected by their appearance
35:
infections per year and 1 million deaths due to AIDS.
5094:
5055:
4185:"The clinical illness promotion factor: a third ingredient"
4147:
4024:
3607:
3443:
3148:
1757:
1632:
640:
308:
result in person-to-person transmission include caring for
4226:"Host factors and the pathogenesis of HIV-induced disease"
3525:
3274:
3104:
2345:"Condoms and STDs: Fact Sheet for Public Health Personnel"
1341:
700:
from these diseases, formerly confined to the elderly and
378:
and no cases have yet been identified through this route.
4579:
4560:
3017:"Researchers Clear 'Patient Zero' From AIDS Origin Story"
2369:
966:
884:
524:
179:
Sexual intercourse with an animal will avoid or cure AIDS
160:
32:
4659:
WHO disease staging system for HIV infection and disease
3983:
3773:
2431:"Pathogenesis of human immunodeficiency virus infection"
1916:
47:
4515:
3934:
2213:
Siemens, D.F. (1987). "AIDS Transmission and Insects".
2119:
1837:
1377:(4th ed.). Boston: Jones and Bartlett Publishers.
985:
In Africa, HIV was first recognized in sexually active
806:
AZT and other antiretroviral drugs, not HIV, cause AIDS
325:
HIV infections cannot be detected based on appearance.
5627:
List of HIV/AIDS cases and deaths registered by region
2995:"How a typo created a scapegoat for the AIDS epidemic"
2775:
2534:
2001:"Human bites: a rare risk factor for HIV transmission"
1873:
1369:
Fan, H.; Conner, R.F.; Villarreal, L.P., eds. (2005).
589:
Origin of AIDS through human–monkey sexual intercourse
4516:
HIV.gov – The U.S. Federal Domestic HIV/AIDS Resource
2414:
National Institute of Allergy and Infectious Diseases
2176:
1411:
1220:"The first postmodern pandemic: 25 years of HIV/AIDS"
531:, has been demonstrated to suppress T cell activity.
361:
into their victims, which may carry diseases such as
207:
1292:
National Institute of Allergy and Infectious Disease
5622:
List of countries by HIV/AIDS adult prevalence rate
5011:
President's Emergency Plan for AIDS Relief (PEPFAR)
4996:
Joint United Nations Programme on HIV/AIDS (UNAIDS)
2677:
1170:Many HIV-infected people turn to complementary and
382:
HIV survives for only a short time outside the body
348:
301:says that this is essentially a no-risk situation.
4379:Littlewood, Rae A; Vandable, Peter A (June 2002).
1958:
1956:
1467:"South African men rape babies as 'cure' for Aids"
1370:
1282:
1280:
1041:Most AIDS symptoms result from the development of
684:The diseases that have come to be associated with
499:to evade the ongoing immune response of the host.
337:is possible, but it is much less likely than from
185:Societies for the Prevention of Cruelty to Animals
4292:
3740:
3705:
3484:
3355:
1999:Bartholomew, Courtenay F; Jones, Avion M (2006).
603:(SIV), a disease present only in chimpanzees and
391:HIV can infect only homosexual men and drug users
74:, which is the key to ultimately defeating AIDS.
5639:
3437:
1998:
1787:
1607:
576:in Los Angeles. This edition would later become
492:damage even after the production of antibodies.
16:Misinformation about the HIV/AIDS and its spread
4610:National Addiction and HIV Data Archive Program
3656:
3601:
3091:
3089:
2363:
1953:
1910:
1716:
1277:
739:
708:people, including well-educated members of the
405:History of HIV/AIDS § Unsterile injections
171:occurrences, including the rape of infants, in
149:Sexual intercourse with a virgin will cure AIDS
3706:Vermund, S.H.; Hoover, D.R.; Chen, K. (1993).
3519:
2408:
2406:
2404:
1613:
704:, are now common among HIV-infected young and
523:, sheds from viral particles and binds to the
316:have occurred, though this is extremely rare.
4545:
4141:
4018:
3977:
3887:
3767:
3699:
3312:
3268:
3227:
2726:
2671:
2479:
2424:
2422:
2249:
2206:
1626:
1593:, March 25, 2002; retrieved February 22, 2007
1493:
1491:
4110:
3846:
3560:
3396:
3178:
3086:
2949:
2321:. Center for Disease Control. Archived from
2290:
2284:
1867:
1831:
1751:
437:This reasoning ignores numerous examples of
4702:Diffuse infiltrative lymphocytosis syndrome
4217:
4176:
4060:: CS1 maint: numeric names: authors list (
3928:
3803:
3098:
2891:: CS1 maint: numeric names: authors list (
2826:
2733:Cold Spring Harbor Perspectives in Medicine
2401:
2041:
1675:
1534:
1335:
1217:
1114:The diseases associated with AIDS, such as
599:While HIV is most likely a mutated form of
421:An HIV-infected person cannot have children
4935:People With AIDS Self-Empowerment Movement
4552:
4538:
4525:Centers for Disease Control and Prevention
3478:
3142:
2419:
2349:Centers for Disease Control and Prevention
2170:
2070:
1725:J Acquir Immune Defic Syndr Hum Retrovirol
1540:
1488:
1460:
1458:
943:, researchers matched 17 HIV-seropositive
329:HIV cannot be transmitted through oral sex
295:Centers for Disease Control and Prevention
52:
4488:
4404:
4200:
4001:
3960:
3911:
3870:
3723:
3625:
3584:
3543:
3502:
3461:
3420:
3379:
3251:
3196:
3069:
2905:
2868:
2801:
2769:
2752:
2720:
2695:
2678:Locatelli, S; Peeters, M (Mar 27, 2012).
2560:
2511:
2462:
2390:
2153:
2096:
2018:
1814:
1699:
1658:
1438:
1235:
861:—HIV—spread through certain communities.
2986:
2899:
2528:
1464:
1100:
1087:
1017:, for example, show no symptoms or only
965:users (a majority of whom are male) and
555:
263:
250:
96:
4338:International Journal of STD & AIDS
3009:
2992:
2485:
2337:
2212:
1455:
1211:
1194:Contaminated haemophilia blood products
195:, recorded beliefs amongst youths that
61:, which is the virus that causes AIDS (
5640:
4470:
4427:
4378:
3027:
2906:Signorile, Michelangelo (2012-01-26).
2729:"Origins of HIV and the AIDS Pandemic"
2727:Sharp, PM; Hahn, BH (September 2011).
1252:
1060:or immunosuppressive drugs to prevent
545:
495:HIV has a well-recognized capacity to
4971:Discredited HIV/AIDS origins theories
4533:
4223:
4182:
4162:10.1093/oxfordjournals.epirev.a036122
3809:
2613:
2611:
2609:
2607:
2605:
1162:to which the patient may be exposed.
583:Morbidity and Mortality Weekly Report
570:Morbidity and Mortality Weekly Report
122:Highly active anti-retroviral therapy
48:The relationship between HIV and AIDS
2655:"Timeline: AIDS moments to remember"
2428:
2077:Expert Opinion on Biological Therapy
1497:
1144:are much more likely than people in
782:, and physician and AIDS researcher
5090:The Freddie Mercury Tribute Concert
4559:
4028:The New England Journal of Medicine
2993:Johnson, Brian D. (17 April 2019).
2311:
2020:10.1097/01.aids.0000210621.13825.75
1967:
1288:"The Evidence that HIV Causes AIDS"
223:is a well-established technique in
13:
2652:
2646:
2602:
2585:"Key HIV strain 'came from Haiti'"
2455:10.1111/j.1749-6632.1989.tb16459.x
1975:"THT: "Ways HIV is not passed on""
1362:
208:HIV antibody testing is unreliable
63:acquired immunodeficiency syndrome
14:
5669:
4676:Countries by AIDS prevalence rate
4509:
4335:
1584:"Bestiality new Aids myth – SPCA"
664:
534:Infected lymphocytes express the
183:In 2002, the National Council of
37:Misconceptions about HIV and AIDS
5137:Democratic Republic of the Congo
4697:AIDS-defining clinical condition
3627:10.1097/00002030-199909100-00012
3164:10.1097/00006454-199908000-00007
2959:The American Journal of Medicine
2634:
1816:10.1097/00002030-199901140-00015
1737:10.1097/00042560-199504000-00014
1237:10.1111/j.1365-2796.2007.01910.x
789:A great deal is known about the
622:Democratic Republic of the Congo
566:Democratic Republic of the Congo
349:HIV is transmitted by mosquitoes
255:Symptoms of acute HIV infection
246:
4464:
4421:
4372:
4329:
4286:
4272:
4096:
4082:
4068:
3642:
2924:
2577:
2113:
2071:Yu, M; Vajdy, M (August 2010).
2064:
2035:
1992:
1596:
1577:
453:virus may persist for years in
3749:J. Acquir. Immune Defic. Syndr
1405:
1391:
1306:
910:listed as the cause of death.
641:Gaëtan Dugas as "patient zero"
304:Other interactions that could
1:
5006:Misconceptions about HIV/AIDS
4986:International AIDS Conference
4940:HIV/AIDS in the porn industry
4883:Discrimination against people
4442:10.1016/S0140-6736(99)05712-8
4003:10.1182/blood.V84.5.1666.1666
3872:10.1182/blood.V82.4.1351.1351
3333:10.1016/S0140-6736(00)02504-6
3290:10.1016/S0140-6736(98)03201-2
3120:10.1016/S0140-6736(95)90519-7
1888:10.1016/S0140-6736(86)92898-9
1853:10.1016/S0928-0197(96)00244-9
1773:10.1016/S1386-6532(99)00043-8
1555:10.1016/S0140-6736(04)16288-0
1465:Flanagan, Jane (2001-11-11).
1431:10.1080/15284336.2017.1311056
1204:
893:Multicenter AIDS Cohort Study
601:simian immunodeficiency virus
397:Gay-related immune deficiency
103:tenofovir disoproxil fumarate
4866:Catholic Church and HIV/AIDS
4747:HIV Drug Resistance Database
4477:Clinical Infectious Diseases
3789:10.7326/0003-4819-113-10-733
3677:10.1016/0140-6736(93)90421-C
3573:Clinical Infectious Diseases
2972:10.1016/0002-9343(84)90668-5
2697:10.1097/QAD.0b013e328350fb68
2619:"A Timeline of HIV and AIDS"
2138:10.1097/QAD.0000000000000298
2089:10.1517/14712598.2010.496776
1224:Journal of Internal Medicine
740:HIV is not the cause of AIDS
401:Anal sex § Health risks
77:
59:human immunodeficiency virus
7:
5167:Côte d'Ivoire (Ivory Coast)
5001:Media portrayal of HIV/AIDS
4930:List of HIV-positive people
4040:10.1056/NEJM198910263211701
3913:10.1056/NEJM199302113280614
3777:Annals of Internal Medicine
3725:10.1056/NEJM199302113280615
3253:10.1056/NEJM199803263381301
2745:10.1101/cshperspect.a006841
1701:10.1056/NEJM199107043250101
1651:10.1128/JCM.28.1.16-19.1990
1265:. World Health Organization
1177:
870:Vancouver, British Columbia
715:For example, in a study in
441:other than HIV that can be
10:
5674:
5067:Reports from the Holocaust
4991:International AIDS Society
4981:Elton John AIDS Foundation
1931:10.1177/000992289803700303
1184:International AIDS Society
880:(Schechter et al., 1993).
809:
743:
668:
644:
592:
549:
394:
343:penile–vaginal intercourse
293:, the risk increases. The
152:
89:HIV/AIDS § Management
86:
72:can prevent new infections
5617:
5587:
5539:
5507:
5457:
5448:
5420:
5255:
5112:
5103:
5026:Treatment Action Campaign
4963:
4848:
4780:
4742:Tuberculosis co-infection
4684:
4605:disease progression rates
4572:
4397:10.1080/09540120701767216
4307:10.1007/s11904-011-0090-8
1373:AIDS: science and society
1344:Medscape General Medicine
897:immunosuppressive therapy
692:, diarrheal diseases and
142:post-exposure prophylaxis
128:levels, and reduction in
29:World Health Organization
4752:Innate resistance to HIV
4722:Neurocognitive disorders
4350:10.1258/0956462054093962
3953:10.1136/bmj.312.7025.207
3422:10.1001/jama.280.17.1497
2270:10.1001/jama.255.14.1887
2192:10.1093/infdis/160.6.970
1473:. London. Archived from
1142:Midwestern United States
1043:opportunistic infections
1003:industrialized countries
671:AIDS conspiracy theories
508:course of the disease.
333:Contracting HIV through
138:Antiretroviral treatment
5073:AIDS–Holocaust metaphor
5056:Gay Men's Health Crisis
4732:Opportunistic infection
3832:10.1126/science.7992044
3152:Pediatr. Infect. Dis. J
2653:Wilson, Jacque Wilson.
2235:10.1126/science.2889266
1049:associated with severe
632:Tennessee State Senator
595:HIV/AIDS § Origins
285:by an infected person.
236:of the antibody tests.
82:
53:HIV is the same as AIDS
4900:HIV-affected community
4840:HIV and homosexual men
3463:10.1001/jama.284.2.190
2553:10.1084/jem.189.9.1489
2486:Richman, D.D. (2000).
1512:10.1258/rsmmsl.43.1.85
1260:"AIDS epidemic update"
1199:Prevention of HIV/AIDS
1111:
1098:
1064:rejection or to treat
908:non-Hodgkin's lymphoma
766:, conservative writer
762:, journalist/activist
725:pulmonary tuberculosis
611:) exist not involving
561:
490:central nervous system
417:can reduce this risk.
269:
256:
118:
93:Management of HIV/AIDS
57:HIV is an acronym for
5080:Silence=Death Project
4878:Criminal transmission
4798:Multiple sex partners
3545:10.1093/aje/152.2.178
1117:Pneumocystis jiroveci
1104:
1094:Pneumocystis jiroveci
1091:
1033:while others do not.
849:recreational drug use
780:Robert Root-Bernstein
559:
299:Terence Higgins Trust
267:
254:
155:Virgin cleansing myth
100:
70:halted. Treating HIV
5402:United Arab Emirates
4873:Circumcision and HIV
4830:City of Hope Patient
4590:structure and genome
4224:Fauci, A.S. (1996).
4183:Evans, A.S. (1982).
4104:"U.S. Bureau Census"
4076:"U.S. Census Bureau"
1218:Kallings LO (2008).
1172:alternative medicine
854:Pneumocystis carinii
752:scientific consensus
4950:AIDS Memorial Quilt
4762:HIV-positive people
4242:1996Natur.384..529F
3824:1994Sci...266.1645C
3579:(Suppl 1): S5–S14.
3062:10.1038/nature19827
3054:2016Natur.539...98W
2912:The Huffington Post
2861:10.1038/nature07390
2853:2008Natur.455..661W
2794:1998Natur.391..594Z
2447:1989NYASA.567...58L
2429:Levy, J.A. (1993).
2227:1987Sci...238..143S
2054:Stanford University
1419:HIV Clinical Trials
1124:Mycobacterium avium
1107:Mycobacterium avium
1072:conditions, severe
1066:autoimmune diseases
939:In a cohort in the
812:Duesberg hypothesis
546:History of HIV/AIDS
5658:HIV/AIDS denialism
5527:Dominican Republic
4910:HIV/AIDS denialism
4835:Women and HIV/AIDS
4825:The London Patient
4692:Signs and symptoms
4600:CDC classification
4295:Curr. HIV/AIDS Rep
4090:"AIDS/HIV Statics"
3190:2007-06-14 at the
2351:. 10 February 2010
1841:Clin. Diagn. Virol
1639:J. Clin. Microbiol
1616:BC Medical Journal
1589:2008-12-19 at the
1294:. 4 September 2009
1112:
1099:
1053:secondary to HIV.
991:sub-Saharan Africa
920:blood transfusions
776:Phillip E. Johnson
772:intelligent design
613:sexual intercourse
562:
461:. Viruses such as
445:after evidence of
270:
257:
119:
5635:
5634:
5613:
5612:
5535:
5534:
5016:The SING Campaign
4905:HIV/AIDS activism
4893:Cost of treatment
4815:Timothy Ray Brown
4810:World AIDS Museum
4189:Yale J. Biol. Med
3818:(5191): 1645–46.
3284:(9142): 1725–30.
2416:, September, 1995
2132:(10): 1509–1519.
1963:"Kissing and HIV"
1549:(9422): 1663–64.
1384:978-0-7637-0086-7
1051:immunosuppression
874:nitrite inhalants
723:individuals with
202:zoonotic diseases
169:child molestation
67:in a latent state
5665:
5605:Papua New Guinea
5455:
5454:
5110:
5109:
4554:
4547:
4540:
4531:
4530:
4503:
4502:
4492:
4468:
4462:
4461:
4436:(9203): 547–48.
4425:
4419:
4418:
4408:
4376:
4370:
4369:
4333:
4327:
4326:
4290:
4284:
4283:
4276:
4270:
4269:
4250:10.1038/384529a0
4236:(6609): 529–34.
4221:
4215:
4214:
4204:
4180:
4174:
4173:
4145:
4139:
4138:
4136:
4135:
4129:
4123:. Archived from
4122:
4114:
4108:
4107:
4100:
4094:
4093:
4086:
4080:
4079:
4072:
4066:
4065:
4059:
4051:
4022:
4016:
4015:
4005:
3981:
3975:
3974:
3964:
3947:(7025): 207–10.
3932:
3926:
3925:
3915:
3891:
3885:
3884:
3874:
3850:
3844:
3843:
3807:
3801:
3800:
3771:
3765:
3764:
3744:
3738:
3737:
3727:
3703:
3697:
3696:
3671:(8846): 658–59.
3660:
3654:
3653:
3646:
3640:
3639:
3629:
3605:
3599:
3598:
3588:
3564:
3558:
3557:
3547:
3532:Am. J. Epidemiol
3523:
3517:
3516:
3506:
3482:
3476:
3475:
3465:
3441:
3435:
3434:
3424:
3415:(17): 1497–503.
3400:
3394:
3393:
3383:
3359:
3353:
3352:
3327:(9226): 291–96.
3316:
3310:
3309:
3272:
3266:
3265:
3255:
3231:
3225:
3224:
3222:
3221:
3215:
3209:. Archived from
3208:
3200:
3194:
3182:
3176:
3175:
3146:
3140:
3139:
3114:(8950): 607–10.
3102:
3096:
3093:
3084:
3083:
3073:
3048:(7627): 98–101.
3031:
3025:
3024:
3013:
3007:
3006:
3004:
3002:
2990:
2984:
2983:
2953:
2947:
2946:
2944:
2942:
2928:
2922:
2921:
2919:
2918:
2903:
2897:
2896:
2890:
2882:
2872:
2847:(7293): 661–64.
2830:
2824:
2823:
2805:
2788:(6667): 594–97.
2773:
2767:
2766:
2756:
2724:
2718:
2717:
2699:
2675:
2669:
2668:
2666:
2665:
2650:
2644:
2638:
2637:
2633:
2631:
2630:
2615:
2600:
2599:
2597:
2596:
2581:
2575:
2574:
2564:
2532:
2526:
2525:
2515:
2483:
2477:
2476:
2466:
2426:
2417:
2410:
2399:
2394:
2388:
2387:
2367:
2361:
2360:
2358:
2356:
2341:
2335:
2334:
2332:
2330:
2315:
2309:
2308:
2288:
2282:
2281:
2253:
2247:
2246:
2210:
2204:
2203:
2174:
2168:
2167:
2157:
2117:
2111:
2110:
2100:
2068:
2062:
2061:
2051:
2039:
2033:
2032:
2022:
1996:
1990:
1989:
1987:
1986:
1977:. Archived from
1971:
1965:
1960:
1951:
1950:
1914:
1908:
1907:
1871:
1865:
1864:
1835:
1829:
1828:
1818:
1795:Nkengasong, J.N.
1791:
1785:
1784:
1755:
1749:
1748:
1720:
1714:
1713:
1703:
1679:
1673:
1672:
1662:
1630:
1624:
1623:
1611:
1605:
1600:
1594:
1581:
1575:
1574:
1538:
1532:
1531:
1495:
1486:
1485:
1483:
1482:
1462:
1453:
1452:
1442:
1409:
1403:
1402:
1395:
1389:
1388:
1376:
1366:
1360:
1359:
1339:
1333:
1332:
1330:
1329:
1320:. Archived from
1310:
1304:
1303:
1301:
1299:
1284:
1275:
1274:
1272:
1270:
1264:
1256:
1250:
1249:
1239:
1215:
1025:inflammation to
972:anal intercourse
878:anal intercourse
784:Joseph Sonnabend
635:Stacey Campfield
477:Varicella zoster
387:minutes if dry.
268:Symptoms of AIDS
221:antibody testing
197:sex with animals
5673:
5672:
5668:
5667:
5666:
5664:
5663:
5662:
5638:
5637:
5636:
5631:
5609:
5583:
5531:
5503:
5444:
5416:
5362:Myanmar (Burma)
5251:
5099:
5085:Day Without Art
5031:The Global Fund
4959:
4888:Economic impact
4844:
4776:
4680:
4632:pathophysiology
4568:
4558:
4512:
4507:
4506:
4469:
4465:
4426:
4422:
4377:
4373:
4334:
4330:
4291:
4287:
4278:
4277:
4273:
4222:
4218:
4195:(3–4): 193–99.
4181:
4177:
4146:
4142:
4133:
4131:
4127:
4120:
4116:
4115:
4111:
4102:
4101:
4097:
4088:
4087:
4083:
4074:
4073:
4069:
4053:
4052:
4034:(17): 1141–48.
4023:
4019:
3982:
3978:
3933:
3929:
3900:N. Engl. J. Med
3892:
3888:
3851:
3847:
3808:
3804:
3772:
3768:
3745:
3741:
3712:N. Engl. J. Med
3704:
3700:
3661:
3657:
3648:
3647:
3643:
3620:(13): 1687–95.
3606:
3602:
3565:
3561:
3524:
3520:
3483:
3479:
3442:
3438:
3401:
3397:
3360:
3356:
3317:
3313:
3273:
3269:
3240:N. Engl. J. Med
3232:
3228:
3219:
3217:
3213:
3206:
3202:
3201:
3197:
3192:Wayback Machine
3183:
3179:
3147:
3143:
3103:
3099:
3094:
3087:
3032:
3028:
3015:
3014:
3010:
3000:
2998:
2991:
2987:
2954:
2950:
2940:
2938:
2930:
2929:
2925:
2916:
2914:
2904:
2900:
2884:
2883:
2831:
2827:
2774:
2770:
2725:
2721:
2676:
2672:
2663:
2661:
2651:
2647:
2635:
2628:
2626:
2617:
2616:
2603:
2594:
2592:
2583:
2582:
2578:
2533:
2529:
2504:10.1172/JCI9478
2492:J. Clin. Invest
2484:
2480:
2427:
2420:
2411:
2402:
2395:
2391:
2368:
2364:
2354:
2352:
2343:
2342:
2338:
2328:
2326:
2325:on 4 March 2011
2317:
2316:
2312:
2289:
2285:
2264:(14): 1887–91.
2254:
2250:
2211:
2207:
2175:
2171:
2118:
2114:
2069:
2065:
2049:
2040:
2036:
1997:
1993:
1984:
1982:
1973:
1972:
1968:
1961:
1954:
1915:
1911:
1872:
1868:
1836:
1832:
1792:
1788:
1756:
1752:
1721:
1717:
1688:N. Engl. J. Med
1680:
1676:
1631:
1627:
1612:
1608:
1601:
1597:
1591:Wayback Machine
1582:
1578:
1539:
1535:
1496:
1489:
1480:
1478:
1463:
1456:
1410:
1406:
1397:
1396:
1392:
1385:
1367:
1363:
1340:
1336:
1327:
1325:
1312:
1311:
1307:
1297:
1295:
1286:
1285:
1278:
1268:
1266:
1262:
1258:
1257:
1253:
1216:
1212:
1207:
1180:
1168:
1086:
1058:glucocorticoids
1039:
999:
958:
929:
916:
845:
825:clinical trials
814:
808:
750:There is broad
748:
742:
682:
677:
669:Main articles:
667:
649:
643:
626:molecular clock
605:African monkeys
597:
591:
554:
548:
505:
464:Cytomegalovirus
435:
423:
407:
393:
384:
375:West Nile virus
351:
331:
322:
262:
249:
210:
181:
157:
151:
95:
85:
80:
55:
50:
17:
12:
11:
5:
5671:
5661:
5660:
5655:
5650:
5648:Misconceptions
5633:
5632:
5630:
5629:
5624:
5618:
5615:
5614:
5611:
5610:
5608:
5607:
5602:
5597:
5591:
5589:
5585:
5584:
5582:
5581:
5576:
5571:
5566:
5561:
5556:
5551:
5545:
5543:
5537:
5536:
5533:
5532:
5530:
5529:
5524:
5519:
5513:
5511:
5505:
5504:
5502:
5501:
5500:
5499:
5489:
5484:
5479:
5474:
5469:
5464:
5458:
5452:
5446:
5445:
5443:
5442:
5437:
5432:
5430:United Kingdom
5426:
5424:
5418:
5417:
5415:
5414:
5409:
5404:
5399:
5394:
5389:
5384:
5379:
5374:
5369:
5364:
5359:
5354:
5349:
5344:
5339:
5334:
5329:
5324:
5319:
5314:
5309:
5308:
5307:
5297:
5292:
5287:
5282:
5277:
5272:
5267:
5261:
5259:
5253:
5252:
5250:
5249:
5244:
5239:
5234:
5229:
5224:
5219:
5214:
5209:
5204:
5199:
5194:
5189:
5184:
5179:
5174:
5169:
5164:
5159:
5154:
5149:
5144:
5139:
5134:
5129:
5124:
5118:
5116:
5107:
5101:
5100:
5098:
5097:
5092:
5087:
5082:
5077:
5076:
5075:
5070:
5063:
5058:
5048:
5043:
5041:YAA/Youthforce
5038:
5036:World AIDS Day
5033:
5028:
5023:
5018:
5013:
5008:
5003:
4998:
4993:
4988:
4983:
4978:
4973:
4967:
4965:
4961:
4960:
4958:
4957:
4952:
4947:
4942:
4937:
4932:
4927:
4922:
4917:
4912:
4907:
4902:
4897:
4896:
4895:
4885:
4880:
4875:
4870:
4869:
4868:
4858:
4852:
4850:
4846:
4845:
4843:
4842:
4837:
4832:
4827:
4822:
4820:Berlin Patient
4817:
4812:
4807:
4802:
4801:
4800:
4790:
4784:
4782:
4778:
4777:
4775:
4774:
4769:
4764:
4759:
4754:
4749:
4744:
4739:
4737:Superinfection
4734:
4729:
4724:
4719:
4717:Cardiomyopathy
4714:
4709:
4704:
4699:
4694:
4688:
4686:
4682:
4681:
4679:
4678:
4673:
4672:
4671:
4669:Teens / Adults
4666:
4656:
4655:
4654:
4649:
4644:
4639:
4634:
4629:
4624:
4614:
4613:
4612:
4607:
4602:
4597:
4592:
4587:
4576:
4574:
4570:
4569:
4557:
4556:
4549:
4542:
4534:
4528:
4527:
4518:
4511:
4510:External links
4508:
4505:
4504:
4490:10.1086/324351
4463:
4420:
4391:(8): 1002–18.
4371:
4344:(6): 395–403.
4328:
4285:
4271:
4216:
4175:
4150:Epidemiol. Rev
4140:
4118:"UNAIDS, 2005"
4109:
4095:
4081:
4067:
4017:
3996:(5): 1666–71.
3976:
3927:
3886:
3865:(4): 1351–57.
3845:
3802:
3783:(10): 733–39.
3766:
3739:
3698:
3655:
3641:
3600:
3586:10.1086/313843
3559:
3518:
3477:
3436:
3395:
3381:10.1086/314623
3368:J. Infect. Dis
3354:
3311:
3267:
3246:(13): 853–60.
3226:
3195:
3177:
3141:
3097:
3085:
3026:
3008:
2985:
2948:
2923:
2898:
2825:
2768:
2739:(1): a006841.
2719:
2670:
2645:
2601:
2576:
2547:(9): 1489–96.
2527:
2478:
2441:(1): 183–289.
2435:Microbiol. Rev
2418:
2400:
2389:
2362:
2336:
2310:
2283:
2248:
2205:
2180:J. Infect. Dis
2169:
2112:
2083:(8): 1181–95.
2063:
2045:(March 2009).
2034:
1991:
1966:
1952:
1909:
1866:
1830:
1786:
1761:J. Clin. Virol
1750:
1715:
1674:
1625:
1606:
1595:
1576:
1533:
1487:
1454:
1425:(3): 100–109.
1404:
1390:
1383:
1361:
1334:
1305:
1276:
1251:
1209:
1208:
1206:
1203:
1202:
1201:
1196:
1191:
1186:
1179:
1176:
1167:
1164:
1150:histoplasmosis
1085:
1082:
1038:
1035:
1007:seroconversion
998:
995:
963:injection-drug
957:
954:
941:United Kingdom
928:
925:
915:
912:
844:
841:
823:In the 1980s,
810:Main article:
807:
804:
756:Peter Duesberg
746:AIDS denialism
744:Main article:
741:
738:
686:AIDS in Africa
681:
678:
675:AIDS denialism
666:
665:AIDS denialism
663:
645:Main article:
642:
639:
590:
587:
552:Origin of AIDS
550:Main article:
547:
544:
504:
501:
470:Herpes simplex
434:
431:
422:
419:
392:
389:
383:
380:
350:
347:
330:
327:
321:
318:
261:
258:
248:
245:
209:
206:
180:
177:
150:
147:
84:
81:
79:
76:
54:
51:
49:
46:
19:The spread of
15:
9:
6:
4:
3:
2:
5670:
5659:
5656:
5654:
5651:
5649:
5646:
5645:
5643:
5628:
5625:
5623:
5620:
5619:
5616:
5606:
5603:
5601:
5598:
5596:
5593:
5592:
5590:
5586:
5580:
5577:
5575:
5572:
5570:
5567:
5565:
5562:
5560:
5557:
5555:
5552:
5550:
5547:
5546:
5544:
5542:
5541:South America
5538:
5528:
5525:
5523:
5520:
5518:
5515:
5514:
5512:
5510:
5506:
5498:
5497:New York City
5495:
5494:
5493:
5492:United States
5490:
5488:
5485:
5483:
5480:
5478:
5475:
5473:
5470:
5468:
5465:
5463:
5460:
5459:
5456:
5453:
5451:
5450:North America
5447:
5441:
5438:
5436:
5433:
5431:
5428:
5427:
5425:
5423:
5419:
5413:
5410:
5408:
5405:
5403:
5400:
5398:
5395:
5393:
5390:
5388:
5385:
5383:
5380:
5378:
5375:
5373:
5370:
5368:
5365:
5363:
5360:
5358:
5355:
5353:
5350:
5348:
5345:
5343:
5340:
5338:
5335:
5333:
5330:
5328:
5325:
5323:
5320:
5318:
5315:
5313:
5310:
5306:
5303:
5302:
5301:
5298:
5296:
5293:
5291:
5288:
5286:
5283:
5281:
5278:
5276:
5273:
5271:
5268:
5266:
5263:
5262:
5260:
5258:
5254:
5248:
5245:
5243:
5240:
5238:
5235:
5233:
5230:
5228:
5225:
5223:
5220:
5218:
5215:
5213:
5210:
5208:
5205:
5203:
5200:
5198:
5195:
5193:
5190:
5188:
5185:
5183:
5180:
5178:
5175:
5173:
5170:
5168:
5165:
5163:
5160:
5158:
5155:
5153:
5150:
5148:
5145:
5143:
5140:
5138:
5135:
5133:
5130:
5128:
5125:
5123:
5120:
5119:
5117:
5115:
5111:
5108:
5106:
5102:
5096:
5093:
5091:
5088:
5086:
5083:
5081:
5078:
5074:
5071:
5069:
5068:
5064:
5062:
5059:
5057:
5054:
5053:
5052:
5049:
5047:
5044:
5042:
5039:
5037:
5034:
5032:
5029:
5027:
5024:
5022:
5019:
5017:
5014:
5012:
5009:
5007:
5004:
5002:
4999:
4997:
4994:
4992:
4989:
4987:
4984:
4982:
4979:
4977:
4974:
4972:
4969:
4968:
4966:
4962:
4956:
4953:
4951:
4948:
4946:
4943:
4941:
4938:
4936:
4933:
4931:
4928:
4926:
4925:Sex education
4923:
4921:
4918:
4916:
4913:
4911:
4908:
4906:
4903:
4901:
4898:
4894:
4891:
4890:
4889:
4886:
4884:
4881:
4879:
4876:
4874:
4871:
4867:
4864:
4863:
4862:
4859:
4857:
4854:
4853:
4851:
4847:
4841:
4838:
4836:
4833:
4831:
4828:
4826:
4823:
4821:
4818:
4816:
4813:
4811:
4808:
4806:
4803:
4799:
4796:
4795:
4794:
4791:
4789:
4786:
4785:
4783:
4779:
4773:
4770:
4768:
4765:
4763:
4760:
4758:
4755:
4753:
4750:
4748:
4745:
4743:
4740:
4738:
4735:
4733:
4730:
4728:
4725:
4723:
4720:
4718:
4715:
4713:
4710:
4708:
4707:Lipodystrophy
4705:
4703:
4700:
4698:
4695:
4693:
4690:
4689:
4687:
4683:
4677:
4674:
4670:
4667:
4665:
4662:
4661:
4660:
4657:
4653:
4650:
4648:
4645:
4643:
4640:
4638:
4635:
4633:
4630:
4628:
4625:
4623:
4620:
4619:
4618:
4615:
4611:
4608:
4606:
4603:
4601:
4598:
4596:
4593:
4591:
4588:
4586:
4583:
4582:
4581:
4578:
4577:
4575:
4571:
4566:
4562:
4555:
4550:
4548:
4543:
4541:
4536:
4535:
4532:
4526:
4522:
4519:
4517:
4514:
4513:
4500:
4496:
4491:
4486:
4483:(2): 234–38.
4482:
4478:
4474:
4467:
4459:
4455:
4451:
4447:
4443:
4439:
4435:
4431:
4424:
4416:
4412:
4407:
4402:
4398:
4394:
4390:
4386:
4382:
4375:
4367:
4363:
4359:
4355:
4351:
4347:
4343:
4339:
4332:
4324:
4320:
4316:
4312:
4308:
4304:
4301:(4): 257–68.
4300:
4296:
4289:
4281:
4275:
4267:
4263:
4259:
4255:
4251:
4247:
4243:
4239:
4235:
4231:
4227:
4220:
4212:
4208:
4203:
4198:
4194:
4190:
4186:
4179:
4171:
4167:
4163:
4159:
4156:(2): 303–18.
4155:
4151:
4144:
4130:on 2013-12-02
4126:
4119:
4113:
4105:
4099:
4091:
4085:
4077:
4071:
4063:
4057:
4049:
4045:
4041:
4037:
4033:
4029:
4021:
4013:
4009:
4004:
3999:
3995:
3991:
3987:
3980:
3972:
3968:
3963:
3958:
3954:
3950:
3946:
3942:
3938:
3931:
3923:
3919:
3914:
3909:
3906:(6): 441–42.
3905:
3901:
3897:
3890:
3882:
3878:
3873:
3868:
3864:
3860:
3856:
3849:
3841:
3837:
3833:
3829:
3825:
3821:
3817:
3813:
3806:
3798:
3794:
3790:
3786:
3782:
3778:
3770:
3762:
3758:
3755:(7): 820–22.
3754:
3750:
3743:
3735:
3731:
3726:
3721:
3717:
3713:
3709:
3702:
3694:
3690:
3686:
3682:
3678:
3674:
3670:
3666:
3659:
3651:
3645:
3637:
3633:
3628:
3623:
3619:
3615:
3611:
3604:
3596:
3592:
3587:
3582:
3578:
3574:
3570:
3563:
3555:
3551:
3546:
3541:
3538:(2): 178–85.
3537:
3533:
3529:
3522:
3514:
3510:
3505:
3500:
3497:(5): 659–65.
3496:
3492:
3488:
3481:
3473:
3469:
3464:
3459:
3456:(2): 190–97.
3455:
3451:
3447:
3440:
3432:
3428:
3423:
3418:
3414:
3410:
3406:
3399:
3391:
3387:
3382:
3377:
3374:(3): 717–20.
3373:
3369:
3365:
3358:
3350:
3346:
3342:
3338:
3334:
3330:
3326:
3322:
3315:
3307:
3303:
3299:
3295:
3291:
3287:
3283:
3279:
3271:
3263:
3259:
3254:
3249:
3245:
3241:
3237:
3230:
3216:on 2017-10-04
3212:
3205:
3199:
3193:
3189:
3186:
3181:
3173:
3169:
3165:
3161:
3158:(8): 689–94.
3157:
3153:
3145:
3137:
3133:
3129:
3125:
3121:
3117:
3113:
3109:
3101:
3092:
3090:
3081:
3077:
3072:
3067:
3063:
3059:
3055:
3051:
3047:
3043:
3042:
3037:
3030:
3022:
3018:
3012:
2996:
2989:
2981:
2977:
2973:
2969:
2966:(3): 487–92.
2965:
2961:
2960:
2952:
2937:
2933:
2927:
2913:
2909:
2902:
2894:
2888:
2880:
2876:
2871:
2866:
2862:
2858:
2854:
2850:
2846:
2842:
2841:
2836:
2829:
2821:
2817:
2813:
2809:
2804:
2803:10.1038/35400
2799:
2795:
2791:
2787:
2783:
2779:
2772:
2764:
2760:
2755:
2750:
2746:
2742:
2738:
2734:
2730:
2723:
2715:
2711:
2707:
2703:
2698:
2693:
2690:(6): 659–73.
2689:
2685:
2681:
2674:
2660:
2656:
2649:
2642:
2641:public domain
2624:
2620:
2614:
2612:
2610:
2608:
2606:
2590:
2586:
2580:
2572:
2568:
2563:
2558:
2554:
2550:
2546:
2542:
2538:
2531:
2523:
2519:
2514:
2509:
2505:
2501:
2498:(5): 565–66.
2497:
2493:
2489:
2482:
2474:
2470:
2465:
2460:
2456:
2452:
2448:
2444:
2440:
2436:
2432:
2425:
2423:
2415:
2409:
2407:
2405:
2398:
2393:
2385:
2381:
2378:(8): 637–46.
2377:
2373:
2366:
2350:
2346:
2340:
2324:
2320:
2314:
2306:
2302:
2299:(7): 410–17.
2298:
2294:
2287:
2279:
2275:
2271:
2267:
2263:
2259:
2252:
2244:
2240:
2236:
2232:
2228:
2224:
2221:(4824): 143.
2220:
2216:
2209:
2201:
2197:
2193:
2189:
2186:(6): 970–77.
2185:
2181:
2173:
2165:
2161:
2156:
2151:
2147:
2143:
2139:
2135:
2131:
2127:
2123:
2116:
2108:
2104:
2099:
2094:
2090:
2086:
2082:
2078:
2074:
2067:
2059:
2055:
2048:
2044:
2038:
2030:
2026:
2021:
2016:
2013:(4): 631–32.
2012:
2008:
2007:
2002:
1995:
1981:on 2015-06-01
1980:
1976:
1970:
1964:
1959:
1957:
1948:
1944:
1940:
1936:
1932:
1928:
1925:(3): 175–78.
1924:
1920:
1919:Clin. Pediatr
1913:
1905:
1901:
1897:
1893:
1889:
1885:
1882:(8511): 863.
1881:
1877:
1870:
1862:
1858:
1854:
1850:
1846:
1842:
1834:
1826:
1822:
1817:
1812:
1809:(1): 109–17.
1808:
1804:
1800:
1796:
1790:
1782:
1778:
1774:
1770:
1766:
1762:
1754:
1746:
1742:
1738:
1734:
1731:(4): 411–19.
1730:
1726:
1719:
1711:
1707:
1702:
1697:
1693:
1689:
1685:
1678:
1670:
1666:
1661:
1656:
1652:
1648:
1644:
1640:
1636:
1629:
1621:
1617:
1610:
1604:
1599:
1592:
1588:
1585:
1580:
1572:
1568:
1564:
1560:
1556:
1552:
1548:
1544:
1537:
1529:
1525:
1521:
1517:
1513:
1509:
1505:
1501:
1500:Med. Sci. Law
1494:
1492:
1477:on 2008-06-12
1476:
1472:
1468:
1461:
1459:
1450:
1446:
1441:
1436:
1432:
1428:
1424:
1420:
1416:
1408:
1400:
1394:
1386:
1380:
1375:
1374:
1365:
1357:
1353:
1349:
1345:
1338:
1324:on 2017-09-21
1323:
1319:
1315:
1309:
1293:
1289:
1283:
1281:
1261:
1255:
1247:
1243:
1238:
1233:
1230:(3): 218–43.
1229:
1225:
1221:
1214:
1210:
1200:
1197:
1195:
1192:
1190:
1187:
1185:
1182:
1181:
1175:
1173:
1163:
1161:
1158:
1153:
1151:
1147:
1146:New York City
1143:
1139:
1135:
1131:
1127:
1125:
1120:
1118:
1110:
1108:
1103:
1097:
1095:
1090:
1081:
1079:
1078:epidemiologic
1075:
1071:
1067:
1063:
1059:
1054:
1052:
1048:
1044:
1034:
1032:
1028:
1024:
1020:
1016:
1010:
1008:
1004:
994:
992:
988:
987:heterosexuals
983:
980:
975:
973:
968:
964:
953:
949:
946:
942:
937:
934:
924:
921:
911:
909:
905:
904:New York City
900:
898:
894:
890:
886:
881:
879:
875:
871:
867:
862:
860:
856:
855:
850:
840:
838:
832:
830:
826:
821:
819:
813:
803:
801:
797:
792:
787:
785:
781:
777:
773:
769:
765:
761:
760:David Rasnick
758:, biochemist
757:
753:
747:
737:
734:
733:immunizations
730:
726:
722:
718:
717:Côte d'Ivoire
713:
711:
707:
703:
699:
695:
691:
687:
676:
672:
662:
660:
659:
654:
648:
638:
636:
633:
629:
627:
623:
618:
614:
610:
606:
602:
596:
586:
584:
579:
575:
571:
567:
558:
553:
543:
541:
537:
532:
530:
526:
522:
518:
513:
511:
500:
498:
493:
491:
487:
483:
479:
478:
473:
471:
466:
465:
460:
456:
452:
448:
444:
440:
430:
428:
418:
416:
412:
406:
402:
398:
388:
379:
376:
372:
368:
364:
360:
356:
346:
344:
340:
336:
326:
317:
315:
311:
307:
306:theoretically
302:
300:
296:
292:
288:
284:
280:
276:
266:
253:
247:HIV infection
244:
242:
237:
233:
230:
226:
222:
218:
214:
205:
203:
198:
194:
190:
186:
176:
174:
170:
166:
162:
156:
146:
143:
139:
133:
131:
127:
123:
116:
112:
108:
107:emtricitabine
104:
99:
94:
90:
75:
73:
68:
64:
60:
45:
43:
38:
34:
30:
26:
22:
5392:Taiwan (ROC)
5382:Saudi Arabia
5232:South Africa
5065:
5051:Larry Kramer
5005:
4793:Epidemiology
4480:
4476:
4466:
4433:
4429:
4423:
4388:
4384:
4374:
4341:
4337:
4331:
4298:
4294:
4288:
4280:"USPHS/IDSA"
4274:
4233:
4229:
4219:
4192:
4188:
4178:
4153:
4149:
4143:
4132:. Retrieved
4125:the original
4112:
4098:
4084:
4070:
4056:cite journal
4031:
4027:
4020:
3993:
3989:
3979:
3944:
3940:
3930:
3903:
3899:
3889:
3862:
3858:
3848:
3815:
3811:
3805:
3780:
3776:
3769:
3752:
3748:
3742:
3715:
3711:
3701:
3668:
3664:
3658:
3644:
3617:
3613:
3603:
3576:
3572:
3562:
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3211:the original
3198:
3185:UNAIDS, 2003
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3095:UNAIDS, 2000
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2591:. 2007-10-30
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764:Celia Farber
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721:seropositive
714:
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694:tuberculosis
683:
656:
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650:
647:Gaëtan Dugas
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363:dengue fever
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189:Johannesburg
182:
173:South Africa
165:sexual abuse
158:
134:
120:
111:elvitegravir
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5600:New Zealand
5472:El Salvador
5377:Philippines
5347:North Korea
5300:China (PRC)
5265:Afghanistan
4955:Product Red
4856:AIDS orphan
4712:Nephropathy
4647:vaccination
3204:"HHS, 2005"
2997:. Maclean's
2541:J. Exp. Med
2293:AIDS Reader
2043:Piya Sorcar
1148:to develop
1031:lung cancer
1015:hepatitis B
800:hepatitis B
768:Tom Bethell
706:middle-aged
510:Macrophages
482:visna virus
427:miscarriage
310:nose bleeds
291:gum disease
187:(NSPCA) in
5642:Categories
5312:East Timor
5285:Bangladesh
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4915:Red ribbon
4757:Serostatus
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4637:prevention
4627:management
4585:Lentivirus
4521:HIV Basics
4430:The Lancet
4134:2005-08-24
3718:(6): 442.
3220:2005-08-23
2936:Politifact
2917:2012-01-30
2664:2018-10-01
2629:2018-09-30
2595:2010-05-04
1985:2007-10-10
1694:(1): 1–5.
1481:2009-03-25
1328:2018-09-30
1205:References
1121:(PCP) and
1062:transplant
866:homosexual
859:retrovirus
688:, such as
628:approach.
593:See also:
536:Fas ligand
459:antibodies
443:pathogenic
395:See also:
355:mosquitoes
153:See also:
115:cobicistat
87:See also:
5595:Australia
5549:Argentina
5509:Caribbean
5487:Nicaragua
5477:Guatemala
5387:Sri Lanka
5322:Indonesia
5105:Locations
5046:"Free Me"
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4767:Nutrition
4622:diagnosis
4385:AIDS Care
2397:WHO, 2005
2355:5 January
2146:0269-9370
2058:TeachAids
1622:(6): 308.
1471:Telegraph
1350:(3): 21.
1160:pathogens
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774:advocate
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5482:Honduras
5397:Thailand
5372:Pakistan
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5295:Cambodia
5247:Zimbabwe
5227:Tanzania
5152:Ethiopia
5147:Eswatini
5132:Botswana
5021:Solidays
4920:Safe sex
4861:Religion
4805:Timeline
4727:Pruritus
4664:Children
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4617:HIV/AIDS
4595:subtypes
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4450:10683007
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4315:21822625
3693:23141531
3636:10509570
3595:10770911
3554:10909955
3513:10102000
3472:10889592
3341:11071184
3306:32223916
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3172:10462337
3136:19384981
3080:27783600
3001:20 April
2941:16 April
2879:18833279
2763:22229120
2714:38760788
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2589:BBC News
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2522:10712427
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2164:24809629
2107:20624114
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1947:30065399
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1587:Archived
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1520:12627683
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1356:12466764
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5280:Bahrain
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5212:Nigeria
5202:Namibia
5177:Lesotho
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3650:"NIAID"
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2870:3682493
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1440:5633001
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1070:genetic
1047:cancers
889:T-cells
829:placebo
574:gay men
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439:viruses
415:condoms
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5569:Guyana
5559:Brazil
5467:Mexico
5462:Canada
5435:Russia
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5407:Turkey
5342:Jordan
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5242:Zambia
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5217:Rwanda
5187:Malawi
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287:Saliva
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5337:Japan
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4362:S2CID
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4128:(PDF)
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5327:Iran
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