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Mesalazine

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Mesalazine is sold under various names including Apriso, Asacol, Asacol HD, Canasa, Delzicol, Fivasa, Lialda, Salofalk, Pentasa, Rowasa, Octasa, and Sfrowasa. In Europe, it is sold under the name Salofalk (rectal suppository).
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Most often reported side-effects are gastrointestinal (GI) (but may also include headache), including: nausea, diarrhea, and abdominal pain.
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Cevallos SA, Lee JY, Velazquez EM, Foegeding NJ, Shelton CD, Tiffany CR, et al. (January 2021). Ehrt S (ed.).
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Common side-effects include headache, nausea, abdominal pain, and fever. Serious side-effects may include
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Exact mechanism of mesalazine is unknown, but is speculated that mesalazine decreases synthesis of
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There is no data on use in pregnant women, but the drug does cross the placenta and is excreted in
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along with the inert carrier molecule 4-aminobenzoyl-beta-alanine. It is in the category of
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Very rarely, use of mesalazine has been associated with an exacerbation of the symptoms of
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In 2022 Germany introduced guidance to use mesalamine to treat acute uncomplicated
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Mesalazine was approved for medical use in the United States in 1987. It is on the
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World Health Organization model list of essential medicines: 22nd list (2021)
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Rapidly & extensively metabolized intestinal mucosal wall and the liver
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InChI=1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)
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and mesalazine. It is also the active component of the prodrug
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certain formulations may result in problems. Mesalazine is an
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Human Medicines Evaluation Division (15 October 2020).
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pathways. It appears to act locally on colonic mucosa.
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World Health Organization's List of Essential Medicines
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mesalamine, 5-aminosalicylic acid, 5-ASA, Mesalamine (
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Treasure Island (FL): StatPearls Publishing. 1686: 1190:"Asacol HD- mesalamine tablet, delayed release" 1179: 362: 4802: 1798:"Mesalamine Uses, Side Effects & Warnings" 1551:Lippincott's Illustrated Reviews: Pharmacology 4779: 3235: 2436: 1835: 1155: 1153: 1151: 1149: 1147: 1145: 3363: 1242:"Lialda- mesalamine tablet, delayed release" 127: 1607: 1605: 994: 992: 23:, also known as acetylsalicylic acid (ASA). 2443: 2429: 1842: 1828: 1142: 990: 988: 986: 984: 982: 980: 978: 976: 974: 972: 581: 558: 447: 1748: 1738: 1663: 1525: 1332: 467: 55:Asacol, Lialda, Pentasa, Delzicol, others 1602: 1506:United European Gastroenterology Journal 1291: 1289: 1287: 1285: 1096:"Regulatory Decision Summary for Mezera" 1070:"Product monograph brand safety updates" 1000:"Mesalamine Monograph for Professionals" 1549:Finkel R, Clark MA, Cubeddu LX (2009). 1412:"Competitive Generic Therapy Approvals" 1313: 969: 554: 427: 100: 5009: 3834: 1048:Therapeutic Goods Administration (TGA) 948: 924: 839:(effective only in colonic diseases). 794:. It works by direct contact with the 572: 271: 246: 2424: 1823: 1619:from the original on 21 December 2016 1499: 1327:. Geneva: World Health Organization. 1282: 915:disease-modifying antirheumatic drugs 527: 507: 259: 118: 86: 68: 4457:Selective COX-2 inhibitors (coxibs): 1727:Canadian Journal of Gastroenterology 1476:"Mesalamine - Drug Usage Statistics" 1456:from the original on 15 January 2024 195: 2566:Tooltip Prostaglandin D2 receptor 2 2509:Tooltip Prostaglandin D2 receptor 1 2207:Intestinal anti-inflammatory agents 1378:"2022 First Generic Drug Approvals" 487: 378: 13: 4428:AM-404 (N-arachidonoylaminophenol) 4246:Anthranilic acids (fenamic acids): 3898:Mesalazine (5-aminosalicylic acid) 2989:Tooltip Prostaglandin EP4 receptor 2874:Tooltip Prostaglandin EP3 receptor 2797:Tooltip Prostaglandin EP2 receptor 2690:Tooltip Prostaglandin EP1 receptor 1297:British national formulary: BNF 76 14: 5063: 4918:γ-Linolenic acid (gamolenic acid) 4264:Meclofenamic acid (meclofenamate) 2673:Tooltip Prostaglandin E2 receptor 2492:Tooltip Prostaglandin D2 receptor 2264:agents, excluding corticosteroids 1426:from the original on 29 June 2023 1392:from the original on 30 June 2023 1018:"Mesalamine Use During Pregnancy" 743:), is a medication used to treat 222: 150: 4994: 4973:Leukotriene signaling modulators 4765:Tooltip Prostaglandin F synthase 4746:Tooltip Prostaglandin E synthase 4705:Tooltip Prostaglandin D synthase 3147:Tooltip Prostaglandin F receptor 1588:10.2165/00042310-200319100-00001 1576:Drugs & Therapy Perspectives 885:, or people who are allergic to 612: 606: 36: 4284:Talinflumic acid (talinflumate) 4274:Morniflumic acid (morniflumate) 4254:Floctafenic acid (floctafenate) 4237:Tiaprofenic acid (tiaprofenate) 1790: 1765: 1714: 1687:Nakashima J, Preuss CV (2022). 1680: 1631: 1567: 1542: 1493: 1468: 1438: 1404: 1370: 1341: 1260: 1100:Drug and Health Products Portal 849: 816: 782:appears safe. In people with a 706:Key:KBOPZPXVLCULAV-UHFFFAOYSA-N 4807:Tooltip Thromboxane A synthase 3858:Aspirin (acetylsalicylic acid) 3072:16,16-Dimethyl Prostaglandin E 1269:"Active substance: mesalazine" 1114: 1088: 1062: 1036: 953: 615: 600: 235: 1: 4966:Receptor/signaling modulators 4788:Tooltip Prostacyclin synthase 4289:Tolfenamic acid (tolfenamate) 4259:Flufenamic acid (flufenamate) 4249:Etofenamic acid (etofenamate) 3305:Prostacyclin (prostaglandin I 3244:Tooltip Prostacyclin receptor 2311:Antidiarrheal micro-organisms 1500:Peery AF (12 November 2022). 1216:"Pentasa- mesalamine capsule" 962: 345:5-Amino-2-hydroxybenzoic acid 3372:Tooltip Thromboxane receptor 1418:Food and Drug Administration 1384:Food and Drug Administration 1354:Food and Drug Administration 1278:. European Medicines Agency. 892: 872: 16:Anti-inflammatory medication 7: 4438:Paracetamol (acetaminophen) 4269:Mefenamic acid (mefenamate) 3923:Salicylate (salicylic acid) 322:5 hours after initial dose. 10: 5068: 4117:Bucloxic acid (blucloxate) 4035:Indometacin (indomethacin) 2153:Camphorated opium tincture 1890:Intestinal anti-infectives 1337:. WHO/MHP/HPS/EML/2021.02. 905:, which is metabolized to 829:inflammatory bowel disease 820: 745:inflammatory bowel disease 590:Chemical and physical data 18: 5042:Drugs developed by AbbVie 4957: 4902: 4800: 4777: 4758: 4739: 4694: 4279:Niflumic acid (niflumate) 3832: 3815: 3590: 3383:Carbocyclic thromboxane A 3361: 3233: 3136: 3061: 2979: 2864: 2787: 2680: 2662: 2556: 2499: 2481: 2464: 2381: 2335: 2310: 2206: 2118: 2064: 1889: 1873: 1321:World Health Organization 897:Mesalazine is the active 714: 689: 669: 665:283 °C (541 °F) 659: 637: 624: 594: 589: 570: 538: 518: 498: 478: 458: 438: 418: 398: 373: 353: 333: 328: 313: 303: 291: 283: 212: 207: 182: 164: 138: 108: 94: 76: 59: 49: 44: 35: 5022:Anti-inflammatory agents 4597:Menatetrenone (vitamin K 4420:Aminophenols (anilines): 2086:, known as Pepto-Bismol) 1881:Oral rehydration therapy 863:Stevens Johnson syndrome 19:Not to be confused with 4923:Dihomo-γ-linolenic acid 4320:Enolic acids (oxicams): 3863:Benorilate (benorylate) 2326:Saccharomyces boulardii 813:million prescriptions. 805:. It is available as a 324:At steady state 7 hours 297:orally: 20–30% absorbed 4722:selenium tetrachloride 4391:Aminonicotinic acids: 2348:Bismuth subsalicylate 2084:bismuth subsalicylate 1980:Succinylsulfathiazole 1975:Phthalylsulfathiazole 1656:10.1128/mBio.03227-20 1446:"The Top 300 of 2021" 823:4-Aminosalicylic acid 737:5-aminosalicylic acid 4040:Indometacin farnesil 3893:Magnesium salicylate 3524:Pinane thromboxane A 3285:Iloprost (ciloprost) 2905:Iloprost (ciloprost) 2711:Iloprost (ciloprost) 2336:Other antidiarrheals 827:It is used to treat 3868:Carbasalate calcium 2185:does not cross BBB: 1740:10.1155/2010/586092 1689:"Mesalamine (USAN)" 1024:. 18 September 2018 949:Society and culture 925:Mechanism of action 867:erythema multiforme 255:(Prescription only) 231:(Prescription only) 32: 4730:selenium disulfide 4362:4-Aminoquinolines: 2408:Never to phase III 1582:(1–4): 1–4. 2003. 1518:10.1002/ueg2.12331 833:ulcerative colitis 807:generic medication 749:ulcerative colitis 681:O=C(O)c1cc(ccc1O)N 28: 4982: 4981: 4898: 4897: 3933:Sodium salicylate 3903:Methyl salicylate 3826: 3811: 3810: 3132: 3131: 2658: 2657: 2475: 2418: 2417: 1858:anti-inflammatory 1560:978-0-7817-7155-9 1358:. 3 November 2018 1248:. 8 November 2021 1222:. 8 November 2021 1130:. 14 October 2020 1102:. 5 February 2024 1050:. 13 January 2023 792:anti-inflammatory 726: 725: 650:Interactive image 540:CompTox Dashboard 275: 263: 250: 238: 226: 154: 121: 71: 5059: 5032:Gastroenterology 4999: 4998: 4997: 4990: 4933:Arachidonic acid 4808: 4804: 4789: 4785: 4766: 4762: 4747: 4743: 4706: 4702: 4529:Others/unsorted: 4104:Propionic acids: 4085:Sulindac sulfide 3850:Salicylic acids: 3841: 3836: 3830: 3829: 3820: 3373: 3369: 3245: 3241: 3148: 3144: 2990: 2986: 2875: 2871: 2798: 2794: 2691: 2687: 2678: 2677: 2674: 2670: 2567: 2563: 2510: 2506: 2497: 2496: 2493: 2489: 2479: 2478: 2469: 2445: 2438: 2431: 2422: 2421: 2319:Escherichia coli 2279:Aminosalicylates 2269:Cromoglicic acid 1844: 1837: 1830: 1821: 1820: 1814: 1813: 1811: 1809: 1804:. 30 August 2019 1794: 1788: 1787: 1785: 1783: 1769: 1763: 1762: 1752: 1742: 1718: 1712: 1711: 1709: 1707: 1684: 1678: 1677: 1667: 1650:(1): e03227–20. 1635: 1629: 1628: 1626: 1624: 1609: 1600: 1599: 1571: 1565: 1564: 1546: 1540: 1539: 1529: 1497: 1491: 1490: 1488: 1486: 1472: 1466: 1465: 1463: 1461: 1442: 1436: 1435: 1433: 1431: 1422:. 29 June 2023. 1408: 1402: 1401: 1399: 1397: 1388:. 3 March 2023. 1374: 1368: 1367: 1365: 1363: 1345: 1339: 1338: 1336: 1317: 1311: 1310: 1293: 1280: 1279: 1273: 1264: 1258: 1257: 1255: 1253: 1238: 1232: 1231: 1229: 1227: 1212: 1206: 1205: 1203: 1201: 1186: 1177: 1176: 1174: 1172: 1157: 1140: 1139: 1137: 1135: 1118: 1112: 1111: 1109: 1107: 1092: 1086: 1085: 1083: 1081: 1066: 1060: 1059: 1057: 1055: 1040: 1034: 1033: 1031: 1029: 1014: 1008: 1007: 996: 812: 731:, also known as 722: 721: 652: 632: 617: 614: 608: 602: 585: 574: 563: 562: 548: 546: 531: 511: 491: 471: 451: 431: 411: 391: 381: 380: 366: 318: 299:rectally: 10–35% 273: 270: 261: 258: 248: 245: 237: 234: 224: 221: 199: 152: 149: 131: 120: 117: 104: 90: 70: 67: 40: 33: 31: 27: 5067: 5066: 5062: 5061: 5060: 5058: 5057: 5056: 5037:Salicylic acids 5007: 5006: 5005: 4995: 4993: 4985: 4983: 4978: 4953: 4949: 4946:Prostaglandin H 4941: 4938:Prostaglandin G 4894: 4806: 4796: 4794:Tranylcypromine 4787: 4783: 4773: 4764: 4754: 4745: 4735: 4726:sodium selenite 4704: 4700: 4690: 4636:Rosmarinic acid 4600: 4408:Sulfonanilides: 4311:Oxyphenbutazone 3837: 3819: 3807: 3586: 3527: 3399: 3386: 3371: 3367: 3357: 3317: 3314:Prostaglandin E 3309:, epoprostenol) 3308: 3243: 3239: 3229: 3204: 3201:Prostaglandin F 3196: 3193:Prostaglandin D 3146: 3142: 3128: 3113: 3110:Prostaglandin F 3075: 3057: 3022: 3019:Prostaglandin E 3013: 3010:Prostaglandin E 2988: 2985: 2975: 2956:Ricinoleic acid 2945: 2942:Prostaglandin E 2936: 2933:Prostaglandin E 2928: 2925:Prostaglandin D 2873: 2870: 2860: 2830: 2827:Prostaglandin E 2821: 2818:Prostaglandin E 2796: 2793: 2783: 2743: 2740:Prostaglandin E 2734: 2731:Prostaglandin E 2689: 2686: 2672: 2668: 2654: 2585: 2582:Prostaglandin D 2565: 2562: 2552: 2523: 2520:Prostaglandin D 2508: 2505: 2491: 2487: 2468: 2460: 2449: 2419: 2414: 2413: 2398:Clinical trials 2377: 2343:Albumin tannate 2331: 2306: 2215:corticosteroids 2202: 2120:Antipropulsives 2114: 2060: 1885: 1869: 1848: 1818: 1817: 1807: 1805: 1796: 1795: 1791: 1781: 1779: 1771: 1770: 1766: 1719: 1715: 1705: 1703: 1685: 1681: 1636: 1632: 1622: 1620: 1613:"Sulfasalazine" 1611: 1610: 1603: 1573: 1572: 1568: 1561: 1547: 1543: 1498: 1494: 1484: 1482: 1474: 1473: 1469: 1459: 1457: 1444: 1443: 1439: 1429: 1427: 1410: 1409: 1405: 1395: 1393: 1376: 1375: 1371: 1361: 1359: 1347: 1346: 1342: 1318: 1314: 1307: 1295: 1294: 1283: 1271: 1265: 1261: 1251: 1249: 1240: 1239: 1235: 1225: 1223: 1214: 1213: 1209: 1199: 1197: 1196:. 15 April 2018 1188: 1187: 1180: 1170: 1168: 1167:. 14 April 2016 1159: 1158: 1143: 1133: 1131: 1120: 1119: 1115: 1105: 1103: 1094: 1093: 1089: 1079: 1077: 1076:. February 2024 1068: 1067: 1063: 1053: 1051: 1042: 1041: 1037: 1027: 1025: 1016: 1015: 1011: 998: 997: 970: 965: 956: 951: 927: 895: 875: 852: 837:Crohn's disease 825: 819: 810: 788:aminosalicylate 772:kidney problems 753:Crohn's disease 717: 715: 710: 707: 702: 697: 696: 685: 682: 677: 676: 655: 630: 620: 611: 605: 566: 542: 534: 514: 494: 474: 454: 434: 414: 394: 377: 369: 349: 346: 341: 340: 323: 316: 298: 293:Bioavailability 285:Pharmacokinetic 279: 203: 167: 160: 141: 134: 24: 17: 12: 11: 5: 5065: 5055: 5054: 5049: 5044: 5039: 5034: 5029: 5024: 5019: 5004: 5003: 4980: 4979: 4977: 4976: 4969: 4962: 4958: 4955: 4954: 4952: 4951: 4947: 4943: 4939: 4935: 4930: 4928:Diacylglycerol 4925: 4920: 4915: 4906: 4904: 4900: 4899: 4896: 4895: 4893: 4892: 4887: 4882: 4877: 4872: 4867: 4862: 4857: 4852: 4847: 4842: 4837: 4832: 4827: 4822: 4817: 4811: 4809: 4798: 4797: 4792: 4790: 4781: 4775: 4774: 4769: 4767: 4756: 4755: 4750: 4748: 4737: 4736: 4734: 4733: 4715: 4709: 4707: 4698: 4692: 4691: 4689: 4688: 4683: 4678: 4673: 4668: 4663: 4658: 4653: 4648: 4643: 4638: 4633: 4628: 4623: 4618: 4613: 4608: 4603: 4598: 4594: 4589: 4584: 4579: 4574: 4569: 4564: 4559: 4554: 4549: 4544: 4539: 4534: 4522: 4517: 4512: 4507: 4502: 4497: 4492: 4487: 4482: 4477: 4472: 4467: 4462: 4450: 4445: 4440: 4435: 4430: 4425: 4413: 4401: 4396: 4384: 4372: 4367: 4355: 4350: 4345: 4340: 4335: 4330: 4325: 4316:Phenylbutazone 4313: 4308: 4303: 4298: 4286: 4281: 4276: 4271: 4266: 4261: 4256: 4251: 4239: 4234: 4229: 4224: 4219: 4214: 4209: 4204: 4199: 4194: 4189: 4184: 4179: 4174: 4169: 4164: 4159: 4154: 4149: 4144: 4139: 4134: 4129: 4124: 4119: 4114: 4109: 4097: 4092: 4087: 4082: 4077: 4072: 4067: 4062: 4057: 4052: 4047: 4042: 4037: 4032: 4027: 4022: 4017: 4012: 4007: 4002: 3997: 3992: 3987: 3982: 3977: 3972: 3967: 3962: 3957: 3952: 3947: 3935: 3930: 3925: 3920: 3915: 3910: 3905: 3900: 3895: 3890: 3885: 3880: 3875: 3870: 3865: 3860: 3855: 3846: 3844: 3827: 3813: 3812: 3809: 3808: 3806: 3805: 3800: 3795: 3790: 3785: 3780: 3775: 3770: 3765: 3760: 3755: 3750: 3745: 3740: 3735: 3730: 3725: 3720: 3715: 3710: 3705: 3700: 3695: 3690: 3685: 3680: 3675: 3670: 3665: 3660: 3655: 3650: 3645: 3640: 3635: 3630: 3625: 3620: 3615: 3610: 3605: 3600: 3594: 3592: 3588: 3587: 3585: 3584: 3579: 3574: 3569: 3564: 3559: 3554: 3549: 3544: 3539: 3534: 3529: 3525: 3521: 3516: 3511: 3506: 3501: 3496: 3491: 3486: 3481: 3476: 3471: 3466: 3461: 3456: 3451: 3446: 3441: 3436: 3431: 3426: 3421: 3412: 3411: 3406: 3401: 3397: 3393: 3388: 3384: 3376: 3374: 3365: 3359: 3358: 3356: 3355: 3346: 3345: 3340: 3335: 3330: 3325: 3320: 3315: 3311: 3306: 3302: 3297: 3292: 3290:Isocarbacyclin 3287: 3282: 3277: 3272: 3267: 3262: 3257: 3248: 3246: 3237: 3231: 3230: 3228: 3227: 3222: 3217: 3212: 3207: 3202: 3198: 3194: 3190: 3185: 3180: 3175: 3170: 3165: 3160: 3151: 3149: 3140: 3134: 3133: 3130: 3129: 3127: 3126: 3121: 3116: 3111: 3107: 3102: 3097: 3092: 3087: 3082: 3077: 3073: 3065: 3063: 3059: 3058: 3056: 3055: 3050: 3045: 3040: 3031: 3030: 3025: 3023:(dinoprostone) 3020: 3016: 3011: 3007: 3002: 2993: 2991: 2983: 2977: 2976: 2974: 2973: 2964: 2963: 2958: 2953: 2948: 2946:(dinoprostone) 2943: 2939: 2934: 2930: 2926: 2922: 2917: 2912: 2910:Isocarbacyclin 2907: 2902: 2897: 2892: 2887: 2878: 2876: 2868: 2862: 2861: 2859: 2858: 2853: 2848: 2839: 2838: 2833: 2831:(dinoprostone) 2828: 2824: 2819: 2815: 2810: 2801: 2799: 2791: 2785: 2784: 2782: 2781: 2776: 2771: 2766: 2761: 2752: 2751: 2746: 2744:(dinoprostone) 2741: 2737: 2732: 2728: 2723: 2718: 2713: 2708: 2703: 2694: 2692: 2684: 2675: 2666: 2660: 2659: 2656: 2655: 2653: 2652: 2647: 2642: 2637: 2632: 2627: 2622: 2617: 2612: 2607: 2602: 2597: 2588: 2587: 2583: 2579: 2570: 2568: 2560: 2554: 2553: 2551: 2550: 2545: 2540: 2531: 2530: 2525: 2521: 2513: 2511: 2503: 2494: 2485: 2476: 2462: 2461: 2448: 2447: 2440: 2433: 2425: 2416: 2415: 2412: 2411: 2410: 2409: 2406: 2395: 2389: 2383: 2382: 2379: 2378: 2376: 2375: 2370: 2365: 2360: 2355: 2350: 2345: 2339: 2337: 2333: 2332: 2330: 2329: 2322: 2314: 2312: 2308: 2307: 2305: 2304: 2303: 2302: 2297: 2292: 2287: 2274: 2273: 2272: 2271: 2257: 2256: 2255: 2254: 2249: 2244: 2239: 2234: 2229: 2227:Hydrocortisone 2224: 2217:acting locally 2210: 2208: 2204: 2203: 2201: 2200: 2190: 2181: 2180: 2175: 2157: 2156: 2150: 2145: 2140: 2133:Opium tincture 2129: 2127: 2116: 2115: 2113: 2112: 2107: 2102: 2097: 2092: 2087: 2077: 2071: 2069: 2062: 2061: 2059: 2058: 2057: 2056: 2054:Broxyquinoline 2043: 2042: 2041: 2040: 2027: 2026: 2025: 2024: 2011: 2010: 2009: 2008: 2003: 1990: 1989: 1988: 1987: 1985:Sulfaguanidine 1982: 1977: 1964: 1963: 1962: 1961: 1956: 1951: 1946: 1941: 1936: 1931: 1926: 1921: 1916: 1911: 1906: 1904:Amphotericin B 1893: 1891: 1887: 1886: 1884: 1883: 1877: 1875: 1871: 1870: 1862:anti-infective 1851:Antidiarrheals 1847: 1846: 1839: 1832: 1824: 1816: 1815: 1789: 1764: 1733:(2): 127–133. 1713: 1679: 1630: 1601: 1566: 1559: 1541: 1512:(9): 913–914. 1492: 1467: 1437: 1403: 1369: 1340: 1312: 1305: 1281: 1259: 1233: 1207: 1178: 1141: 1113: 1087: 1061: 1035: 1009: 967: 966: 964: 961: 955: 952: 950: 947: 939:cyclooxygenase 926: 923: 919:PPAR-γ agonist 894: 891: 883:kidney disease 874: 871: 851: 848: 844:diverticulitis 818: 815: 768:liver problems 724: 723: 712: 711: 709: 708: 705: 703: 700: 692: 691: 690: 687: 686: 684: 683: 680: 672: 671: 670: 667: 666: 663: 657: 656: 654: 653: 645: 643: 635: 634: 628: 622: 621: 618: 609: 603: 598: 592: 591: 587: 586: 576: 568: 567: 565: 564: 551: 549: 536: 535: 533: 532: 524: 522: 516: 515: 513: 512: 504: 502: 496: 495: 493: 492: 484: 482: 476: 475: 473: 472: 464: 462: 456: 455: 453: 452: 444: 442: 436: 435: 433: 432: 424: 422: 416: 415: 413: 412: 404: 402: 396: 395: 393: 392: 384: 382: 371: 370: 368: 367: 359: 357: 351: 350: 348: 347: 344: 336: 335: 334: 331: 330: 326: 325: 320: 311: 310: 307: 301: 300: 295: 289: 288: 281: 280: 278: 277: 268: 256: 243: 232: 218: 216: 210: 209: 205: 204: 202: 201: 188: 186: 180: 179: 170: 168:administration 162: 161: 159: 158: 156: 146: 144: 136: 135: 133: 132: 114: 112: 106: 105: 98: 92: 91: 84: 74: 73: 61: 57: 56: 53: 47: 46: 42: 41: 15: 9: 6: 4: 3: 2: 5064: 5053: 5050: 5048: 5045: 5043: 5040: 5038: 5035: 5033: 5030: 5028: 5025: 5023: 5020: 5018: 5015: 5014: 5012: 5002: 4992: 4991: 4988: 4975: 4974: 4970: 4968: 4967: 4963: 4960: 4959: 4956: 4950: 4944: 4942: 4936: 4934: 4931: 4929: 4926: 4924: 4921: 4919: 4916: 4914: 4913:Linoleic acid 4911: 4908: 4907: 4905: 4901: 4891: 4888: 4886: 4883: 4881: 4878: 4876: 4873: 4871: 4868: 4866: 4863: 4861: 4858: 4856: 4853: 4851: 4848: 4846: 4843: 4841: 4838: 4836: 4833: 4831: 4828: 4826: 4823: 4821: 4818: 4816: 4813: 4812: 4810: 4805: 4799: 4795: 4791: 4786: 4776: 4772: 4768: 4763: 4757: 4753: 4749: 4744: 4738: 4731: 4727: 4723: 4719: 4716: 4714: 4711: 4710: 4708: 4703: 4693: 4687: 4684: 4682: 4679: 4677: 4674: 4672: 4669: 4667: 4664: 4662: 4659: 4657: 4654: 4652: 4649: 4647: 4644: 4642: 4639: 4637: 4634: 4632: 4629: 4627: 4624: 4622: 4619: 4617: 4614: 4612: 4609: 4607: 4604: 4602: 4595: 4593: 4590: 4588: 4585: 4583: 4580: 4578: 4575: 4573: 4570: 4568: 4565: 4563: 4560: 4558: 4555: 4553: 4550: 4548: 4545: 4543: 4540: 4538: 4535: 4533: 4530: 4526: 4523: 4521: 4518: 4516: 4513: 4511: 4508: 4506: 4503: 4501: 4498: 4496: 4493: 4491: 4488: 4486: 4483: 4481: 4478: 4476: 4473: 4471: 4468: 4466: 4463: 4461: 4458: 4454: 4451: 4449: 4446: 4444: 4441: 4439: 4436: 4434: 4431: 4429: 4426: 4424: 4421: 4417: 4414: 4412: 4409: 4405: 4402: 4400: 4397: 4395: 4392: 4388: 4385: 4383: 4382:Fluproquazone 4380: 4379:Quinazolines: 4376: 4373: 4371: 4368: 4366: 4363: 4359: 4356: 4354: 4351: 4349: 4346: 4344: 4341: 4339: 4336: 4334: 4331: 4329: 4326: 4324: 4321: 4317: 4314: 4312: 4309: 4307: 4304: 4302: 4299: 4297: 4294: 4290: 4287: 4285: 4282: 4280: 4277: 4275: 4272: 4270: 4267: 4265: 4262: 4260: 4257: 4255: 4252: 4250: 4247: 4243: 4240: 4238: 4235: 4233: 4230: 4228: 4225: 4223: 4220: 4218: 4215: 4213: 4210: 4208: 4205: 4203: 4200: 4198: 4195: 4193: 4190: 4188: 4185: 4183: 4180: 4178: 4175: 4173: 4170: 4168: 4165: 4163: 4160: 4158: 4157:Flunoxaprofen 4155: 4153: 4150: 4148: 4145: 4143: 4142:Dexketoprofen 4140: 4138: 4137:Dexindoprofen 4135: 4133: 4130: 4128: 4125: 4123: 4120: 4118: 4115: 4113: 4110: 4108: 4105: 4101: 4098: 4096: 4093: 4091: 4088: 4086: 4083: 4081: 4078: 4076: 4075:Proglumetacin 4073: 4071: 4068: 4066: 4063: 4061: 4058: 4056: 4053: 4051: 4048: 4046: 4043: 4041: 4038: 4036: 4033: 4031: 4028: 4026: 4023: 4021: 4018: 4016: 4013: 4011: 4008: 4006: 4005:Difenpiramide 4003: 4001: 3998: 3996: 3993: 3991: 3988: 3986: 3983: 3981: 3978: 3976: 3973: 3971: 3968: 3966: 3963: 3961: 3958: 3956: 3953: 3951: 3948: 3946: 3943: 3942:Acetic acids: 3939: 3936: 3934: 3931: 3929: 3926: 3924: 3921: 3919: 3916: 3914: 3911: 3909: 3906: 3904: 3901: 3899: 3896: 3894: 3891: 3889: 3886: 3884: 3881: 3879: 3876: 3874: 3871: 3869: 3866: 3864: 3861: 3859: 3856: 3854: 3851: 3848: 3847: 3845: 3843: 3831: 3828: 3824: 3818: 3814: 3804: 3801: 3799: 3796: 3794: 3791: 3789: 3786: 3784: 3781: 3779: 3776: 3774: 3771: 3769: 3766: 3764: 3761: 3759: 3756: 3754: 3751: 3749: 3746: 3744: 3741: 3739: 3736: 3734: 3731: 3729: 3726: 3724: 3721: 3719: 3716: 3714: 3711: 3709: 3706: 3704: 3701: 3699: 3696: 3694: 3691: 3689: 3686: 3684: 3681: 3679: 3676: 3674: 3673:Fenprostalene 3671: 3669: 3666: 3664: 3661: 3659: 3656: 3654: 3651: 3649: 3646: 3644: 3641: 3639: 3636: 3634: 3631: 3629: 3626: 3624: 3623:Delprostenate 3621: 3619: 3616: 3614: 3611: 3609: 3606: 3604: 3601: 3599: 3596: 3595: 3593: 3589: 3583: 3580: 3578: 3575: 3573: 3570: 3568: 3565: 3563: 3560: 3558: 3555: 3553: 3550: 3548: 3545: 3543: 3540: 3538: 3535: 3533: 3530: 3528: 3522: 3520: 3517: 3515: 3512: 3510: 3507: 3505: 3502: 3500: 3497: 3495: 3492: 3490: 3487: 3485: 3482: 3480: 3477: 3475: 3472: 3470: 3467: 3465: 3462: 3460: 3457: 3455: 3452: 3450: 3447: 3445: 3442: 3440: 3437: 3435: 3432: 3430: 3427: 3425: 3422: 3420: 3417: 3414: 3413: 3410: 3407: 3405: 3402: 3400: 3396:Thromboxane A 3394: 3392: 3389: 3387: 3381: 3378: 3377: 3375: 3370: 3360: 3354: 3351: 3348: 3347: 3344: 3341: 3339: 3336: 3334: 3331: 3329: 3326: 3324: 3321: 3319: 3318:(alprostadil) 3312: 3310: 3303: 3301: 3298: 3296: 3293: 3291: 3288: 3286: 3283: 3281: 3278: 3276: 3273: 3271: 3268: 3266: 3263: 3261: 3258: 3256: 3253: 3250: 3249: 3247: 3242: 3232: 3226: 3223: 3221: 3218: 3216: 3213: 3211: 3208: 3206: 3199: 3197: 3191: 3189: 3186: 3184: 3181: 3179: 3176: 3174: 3171: 3169: 3166: 3164: 3161: 3159: 3156: 3153: 3152: 3150: 3145: 3135: 3125: 3122: 3120: 3117: 3115: 3108: 3106: 3103: 3101: 3098: 3096: 3093: 3091: 3088: 3086: 3083: 3081: 3078: 3076: 3070: 3067: 3066: 3064: 3060: 3054: 3051: 3049: 3046: 3044: 3041: 3039: 3036: 3033: 3032: 3029: 3026: 3024: 3017: 3015: 3014:(alprostadil) 3008: 3006: 3003: 3001: 2998: 2995: 2994: 2992: 2987: 2978: 2972: 2969: 2966: 2965: 2962: 2959: 2957: 2954: 2952: 2949: 2947: 2940: 2938: 2937:(alprostadil) 2931: 2929: 2923: 2921: 2918: 2916: 2913: 2911: 2908: 2906: 2903: 2901: 2898: 2896: 2893: 2891: 2888: 2886: 2883: 2880: 2879: 2877: 2872: 2863: 2857: 2854: 2852: 2849: 2847: 2844: 2841: 2840: 2837: 2834: 2832: 2825: 2823: 2822:(alprostadil) 2816: 2814: 2811: 2809: 2806: 2803: 2802: 2800: 2795: 2786: 2780: 2777: 2775: 2772: 2770: 2767: 2765: 2762: 2760: 2757: 2754: 2753: 2750: 2747: 2745: 2738: 2736: 2735:(alprostadil) 2729: 2727: 2724: 2722: 2719: 2717: 2714: 2712: 2709: 2707: 2704: 2702: 2699: 2696: 2695: 2693: 2688: 2679: 2676: 2671: 2661: 2651: 2648: 2646: 2643: 2641: 2638: 2636: 2633: 2631: 2628: 2626: 2623: 2621: 2618: 2616: 2613: 2611: 2608: 2606: 2603: 2601: 2598: 2596: 2593: 2590: 2589: 2586: 2580: 2578: 2575: 2572: 2571: 2569: 2564: 2555: 2549: 2546: 2544: 2541: 2539: 2536: 2533: 2532: 2529: 2526: 2524: 2518: 2515: 2514: 2512: 2507: 2498: 2495: 2490: 2480: 2477: 2473: 2467: 2463: 2459: 2456: 2453: 2446: 2441: 2439: 2434: 2432: 2427: 2426: 2423: 2407: 2405: 2402: 2401: 2399: 2396: 2393: 2390: 2388: 2385: 2384: 2380: 2374: 2371: 2369: 2366: 2364: 2361: 2359: 2356: 2354: 2351: 2349: 2346: 2344: 2341: 2340: 2338: 2334: 2328: 2327: 2323: 2321: 2320: 2316: 2315: 2313: 2309: 2301: 2298: 2296: 2293: 2291: 2288: 2286: 2285:Sulfasalazine 2283: 2282: 2281: 2280: 2276: 2275: 2270: 2267: 2266: 2265: 2263: 2259: 2258: 2253: 2252:Beclometasone 2250: 2248: 2245: 2243: 2240: 2238: 2237:Betamethasone 2235: 2233: 2230: 2228: 2225: 2223: 2220: 2219: 2218: 2216: 2212: 2211: 2209: 2205: 2198: 2194: 2191: 2189: 2186: 2183: 2182: 2179: 2176: 2173: 2169: 2168:Diphenoxylate 2166: 2164: 2159: 2158: 2154: 2151: 2149: 2146: 2144: 2141: 2138: 2134: 2131: 2130: 2128: 2125: 2121: 2117: 2111: 2108: 2106: 2103: 2101: 2098: 2096: 2093: 2091: 2088: 2085: 2081: 2078: 2076: 2073: 2072: 2070: 2068: 2063: 2055: 2052: 2051: 2050: 2049: 2045: 2044: 2039: 2036: 2035: 2034: 2033: 2029: 2028: 2023: 2020: 2019: 2018: 2017: 2013: 2012: 2007: 2004: 2002: 1999: 1998: 1997: 1996: 1992: 1991: 1986: 1983: 1981: 1978: 1976: 1973: 1972: 1971: 1970: 1966: 1965: 1960: 1957: 1955: 1952: 1950: 1947: 1945: 1942: 1940: 1937: 1935: 1932: 1930: 1927: 1925: 1922: 1920: 1917: 1915: 1912: 1910: 1907: 1905: 1902: 1901: 1900: 1899: 1895: 1894: 1892: 1888: 1882: 1879: 1878: 1876: 1872: 1867: 1863: 1859: 1856: 1852: 1845: 1840: 1838: 1833: 1831: 1826: 1825: 1822: 1803: 1799: 1793: 1778: 1774: 1768: 1760: 1756: 1751: 1746: 1741: 1736: 1732: 1728: 1724: 1717: 1702: 1698: 1694: 1690: 1683: 1675: 1671: 1666: 1661: 1657: 1653: 1649: 1645: 1641: 1634: 1618: 1614: 1608: 1606: 1597: 1593: 1589: 1585: 1581: 1577: 1570: 1562: 1556: 1552: 1545: 1537: 1533: 1528: 1523: 1519: 1515: 1511: 1507: 1503: 1496: 1481: 1477: 1471: 1455: 1451: 1447: 1441: 1425: 1421: 1419: 1413: 1407: 1391: 1387: 1385: 1379: 1373: 1357: 1355: 1350: 1344: 1335: 1330: 1326: 1322: 1316: 1308: 1306:9780857113382 1302: 1298: 1292: 1290: 1288: 1286: 1277: 1270: 1263: 1247: 1243: 1237: 1221: 1217: 1211: 1195: 1191: 1185: 1183: 1166: 1162: 1156: 1154: 1152: 1150: 1148: 1146: 1129: 1128: 1127:Health Canada 1123: 1117: 1101: 1097: 1091: 1075: 1074:Health Canada 1071: 1065: 1049: 1045: 1039: 1023: 1019: 1013: 1005: 1001: 995: 993: 991: 989: 987: 985: 983: 981: 979: 977: 975: 973: 968: 960: 946: 944: 943:lipooxygenase 940: 936: 932: 931:prostaglandin 922: 920: 916: 912: 908: 907:sulfapyridine 904: 903:sulfasalazine 900: 890: 888: 884: 880: 870: 868: 864: 860: 855: 847: 845: 840: 838: 834: 830: 824: 814: 808: 804: 799: 797: 793: 789: 785: 784:sulfa allergy 781: 780:breastfeeding 777: 773: 769: 765: 760: 758: 754: 750: 746: 742: 738: 734: 730: 720: 713: 704: 699: 698: 695: 688: 679: 678: 675: 668: 664: 662: 661:Melting point 658: 651: 647: 646: 644: 641: 636: 629: 627: 623: 599: 597: 593: 588: 584: 580: 577: 575: 573:ECHA InfoCard 569: 561: 557: 556:DTXSID5024506 553: 552: 550: 541: 537: 530: 526: 525: 523: 521: 517: 510: 506: 505: 503: 501: 497: 490: 486: 485: 483: 481: 477: 470: 466: 465: 463: 461: 457: 450: 446: 445: 443: 441: 437: 430: 426: 425: 423: 421: 417: 410: 406: 405: 403: 401: 397: 390: 386: 385: 383: 376: 372: 365: 361: 360: 358: 356: 352: 343: 342: 339: 332: 327: 321: 319: 312: 308: 306: 302: 296: 294: 290: 286: 282: 276: Rx-only 269: 267: 257: 254: 244: 242: 233: 230: 220: 219: 217: 215: 211: 206: 198: 193: 190: 189: 187: 185: 181: 178: 174: 171: 169: 163: 157: 148: 147: 145: 143: 137: 130: 125: 116: 115: 113: 111: 107: 103: 99: 97: 93: 89: 85: 83: 79: 75: 66: 62: 58: 54: 52: 48: 45:Clinical data 43: 39: 34: 26: 22: 5052:Orphan drugs 5027:Antioxidants 4971: 4964: 4909: 4528: 4456: 4453:Propacetamol 4443:Parapropamol 4419: 4407: 4390: 4378: 4370:Floctafenine 4361: 4319: 4296:Azapropazone 4293:Pyrazolones: 4292: 4245: 4227:Tarenflurbil 4162:Flurbiprofen 4132:Dexibuprofen 4112:Benoxaprofen 4107:Alminoprofen 4103: 4030:Glucametacin 3941: 3918:Salicylamide 3908:Salacetamide 3897: 3849: 3798:Trimoprostil 3793:Tiprostanide 3778:Spiriprostil 3713:Naxaprostene 3663:Esuberaprost 3618:Cobiprostone 3416:Antagonists: 3415: 3379: 3350:Antagonists: 3349: 3343:Treprostinil 3251: 3183:Fluprostenol 3173:Cloprostenol 3154: 3068: 3035:Antagonists: 3034: 3000:Lubiprostone 2996: 2968:Antagonists: 2967: 2881: 2843:Antagonists: 2842: 2836:Treprostinil 2804: 2756:Antagonists: 2755: 2721:Lubiprostone 2697: 2592:Antagonists: 2591: 2573: 2535:Antagonists: 2534: 2528:Treprostinil 2516: 2368:Racecadotril 2324: 2317: 2289: 2277: 2262:antiallergic 2260: 2222:Prednisolone 2213: 2197:+simethicone 2184: 2160: 2100:Crospovidone 2048:Oxyquinoline 2046: 2030: 2014: 2001:Nifuroxazide 1993: 1969:Sulfonamides 1967: 1954:Streptomycin 1896: 1806:. 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Retrieved 1021: 1012: 1003: 957: 928: 896: 876: 856: 853: 850:Side-effects 841: 831:, including 826: 817:Medical uses 800: 764:pericarditis 761: 747:, including 740: 736: 732: 728: 727: 716:   315:Elimination 214:Legal status 208:Legal status 110:License data 25: 4910:Precursors: 4850:Nicogrelate 4830:Furegrelate 4771:Bimatoprost 4681:Trifenagrel 4671:Tiflamizole 4641:Rutecarpine 4626:Resveratrol 4567:Glimepiride 4532:Anitrazafen 4510:Robenacoxib 4490:Lumiracoxib 4423:Acetanilide 4365:Antrafenine 4323:Ampiroxicam 4217:Pranoprofen 4202:Naproxcinod 4095:Zidometacin 4020:Fenclofenac 3945:Aceclofenac 3883:Ethenzamide 3878:Dipyrocetyl 3773:Rosaprostol 3753:Posaraprost 3738:Penprostene 3728:Ornoprostil 3708:Mexiprostil 3703:Meteneprost 3658:Eptaloprost 3633:Dimoxaprost 3598:Arbaprostil 3552:Seratrodast 3444:BMS-180,291 3275:Carbacyclin 3225:Unoprostone 3205:(dinoprost) 3188:Latanoprost 3163:Bimatoprost 3158:Alfaprostol 3114:(dinoprost) 3053:ONO-AE3-208 3005:Misoprostol 2961:Sulprostone 2951:Remiprostol 2920:Misoprostol 2915:Latanoprost 2890:Carbacyclin 2851:PF-04418948 2813:Misoprostol 2749:Sulprostone 2726:Misoprostol 2716:Latanoprost 2650:Vidupiprant 2640:Timapiprant 2635:Setipiprant 2610:Fevipiprant 2577:Indometacin 2548:Vidupiprant 2543:Laropiprant 2394:from market 2300:Balsalazide 2188:Eluxadoline 2155:(paregoric) 2110:Diosmectite 2105:Attapulgite 2082:(including 2065:Intestinal 1944:Polymyxin B 1939:Paromomycin 1914:Fidaxomicin 1898:Antibiotics 1874:Rehydration 1706:1 September 1200:30 December 1171:30 December 1028:30 December 954:Brand names 935:leukotriene 911:balsalazide 879:breast milk 633: g·mol 579:100.001.745 329:Identifiers 96:MedlinePlus 60:Other names 51:Trade names 5011:Categories 4880:Samixogrel 4875:Rolafagrel 4860:Picotamide 4840:Midazogrel 4815:Camonagrel 4676:Timegadine 4621:Pamicogrel 4592:Licofelone 4572:Hyperforin 4537:Clobuzarit 4525:Valdecoxib 4520:Tilmacoxib 4505:Polmacoxib 4480:Etoricoxib 4448:Phenacetin 4416:Nimesulide 4394:Clonixeril 4387:Proquazone 4343:Lornoxicam 4242:Vedaprofen 4192:Miroprofen 4187:Loxoprofen 4182:Ketoprofen 4177:Indoprofen 4152:Fenoprofen 4065:Oxametacin 4060:Nabumetone 4000:Diclofenac 3995:Clometacin 3990:Cinmetacin 3985:Bumadizone 3965:Alclofenac 3950:Acemetacin 3888:Guacetisal 3873:Diflunisal 3823:inhibitors 3788:Tilsuprost 3768:Rivenprost 3763:Rioprostil 3758:Prostalene 3743:Pimilprost 3733:Oxoprostol 3723:Nocloprost 3698:Luprostiol 3688:Lanproston 3683:Froxiprost 3678:Flunoprost 3668:Etiproston 3653:Enisoprost 3648:Eganoprost 3608:Ciprostene 3577:Terutroban 3567:Sulotroban 3547:Samixogrel 3532:Ramatroban 3519:Picotamide 3504:Mipitroban 3499:Linotroban 3484:Imitrodast 3474:ICI-192605 3469:ICI-185282 3454:Domitroban 3434:Argatroban 3333:Taprostene 3255:ACT-333679 3220:Travoprost 3215:Tafluprost 3210:Sulotroban 3168:Carboprost 3124:Taprenepag 3105:Omidenepag 3100:Nocloprost 3090:Evatanepag 3085:Carboprost 3038:Grapiprant 2630:Ramatroban 2538:Asapiprant 2458:modulators 2452:Prostanoid 2373:Kaopectate 2363:Octreotide 2358:Crofelemer 2295:Olsalazine 2290:Mesalazine 2247:Budesonide 2242:Tixocortol 2232:Prednisone 2193:Loperamide 2067:adsorbents 2022:Miconazole 1995:Nitrofuran 1959:Vancomycin 1855:intestinal 1777:ChemIDplus 1693:StatPearls 1623:8 December 1485:14 January 1460:14 January 963:References 821:See also: 796:intestines 733:mesalamine 729:Mesalazine 638:3D model ( 626:Molar mass 509:CHEBI:6775 469:4Q81I59GXC 440:ChemSpider 400:IUPHAR/BPS 355:CAS Number 338:IUPAC name 305:Metabolism 129:Mesalamine 30:Mesalazine 4885:Terbogrel 4865:Pirmagrel 4825:Dazoxiben 4820:Dazmegrel 4713:Retinoids 4631:Romazarit 4577:Itazigrel 4562:FR-122047 4557:Flumizole 4515:Rofecoxib 4500:Parecoxib 4495:Mavacoxib 4485:Firocoxib 4475:Deracoxib 4470:Cimicoxib 4465:Celecoxib 4460:Apricoxib 4411:Flosulide 4375:Glafenine 4358:Tenoxicam 4353:Piroxicam 4348:Meloxicam 4232:Tepoxalin 4212:Pirprofen 4207:Oxaprozin 4172:Ibuproxam 4167:Ibuprofen 4127:Carprofen 4122:Butibufen 4100:Zomepirac 4070:Oxindanac 4055:Mofezolac 4050:Lonazolac 4045:Ketorolac 4025:Fentiazac 3980:Bufexamac 3975:Bromfenac 3955:Aclofenac 3938:Triflusal 3928:Salsalate 3853:Aloxiprin 3803:Viprostol 3748:Piriprost 3718:Nileprost 3693:Limaprost 3643:Ecraprost 3638:Doxaprost 3628:Deprostil 3613:Clinprost 3572:Terbogrel 3562:SQ-29,548 3557:SQ-28,668 3514:ONO-11120 3479:Ifetroban 3449:Daltroban 3439:Bay U3405 3409:Vapiprost 3380:Agonists: 3353:RO1138452 3328:Selexipag 3323:Ralinepag 3280:Cicaprost 3270:BMY-45778 3265:Beraprost 3252:Agonists: 3178:Enprostil 3155:Agonists: 3119:Simenepag 3095:Gemeprost 3069:Agonists: 3043:GW-627368 2997:Agonists: 2900:Enprostil 2895:Cicaprost 2885:Beraprost 2882:Agonists: 2808:Butaprost 2805:Agonists: 2706:Enprostil 2701:Beraprost 2698:Agonists: 2605:Bay U3405 2574:Agonists: 2517:Agonists: 2455:signaling 2404:Phase III 2392:Withdrawn 2353:Ceratonia 2178:Difenoxin 2172:+atropine 2038:Acetarsol 2032:Arsenical 2016:Imidazole 2006:Nifurzide 1949:Rifaximin 1924:Natamycin 1919:Kanamycin 1808:2 October 1802:Drugs.com 1782:2 October 1596:195230977 1022:Drugs.com 1004:Drugs.com 893:Chemistry 873:Pregnancy 776:pregnancy 774:. Use in 529:ChEMBL704 317:half-life 166:Routes of 140:Pregnancy 88:Monograph 82:Drugs.com 5017:Anilines 5001:Medicine 4961:See also 4870:Ridogrel 4845:Nafagrel 4835:Isbogrel 4718:Selenium 4686:Tropesin 4661:SC-58125 4646:Satigrel 4611:NCX-4040 4587:L-670596 4582:L-655240 4542:Curcumin 4404:Flunixin 4399:Clonixin 4338:Isoxicam 4333:Enolicam 4328:Droxicam 4306:Isopyrin 4301:Dipyrone 4222:Suprofen 4197:Naproxen 4147:Fenbufen 4090:Tolmetin 4080:Sulindac 4015:Felbinac 4010:Etodolac 3970:Bendazac 3783:Tiaprost 3603:Ataprost 3591:Unsorted 3537:Ridogrel 3509:ONO-3708 3494:L-670596 3489:L-655240 3464:GR-32191 3080:Aganepag 3062:Unsorted 3048:L-161982 3028:TCS-2510 2971:L-798106 2856:TG 4-155 2779:SC-51322 2774:SC-51089 2769:SC-19220 2764:ONO-8130 2600:AZD-1981 2595:ADC-3680 2466:Receptor 2161:crosses 2148:Morphine 2137:laudanum 2075:Charcoal 1934:Nystatin 1929:Neomycin 1909:Colistin 1864:agents ( 1759:20151072 1701:31869178 1674:33468700 1617:Archived 1536:36302089 1480:ClinCalc 1454:Archived 1450:ClinCalc 1424:Archived 1390:Archived 1323:(2021). 1246:DailyMed 1220:DailyMed 1194:DailyMed 1134:17 April 1080:24 March 757:rectally 719:(verify) 420:DrugBank 184:ATC code 173:By mouth 142:category 124:DailyMed 4890:U63557A 4855:Ozagrel 4666:Tenidap 4606:NCX-466 4552:FK-3311 4547:DuP-697 4433:Bucetin 3960:Amfenac 3913:Salicin 3582:TRA-418 3429:AA-2414 3419:12-HETE 3404:U-46619 3338:TRA-418 3295:MRE-269 2846:AH-6809 2759:AH-6809 2645:TM30089 2625:QAV-680 2620:MK-7246 2615:MK-1029 2472:ligands 2143:Codeine 2124:opioids 2080:Bismuth 1750:2852235 1665:7845635 1527:9731652 1430:29 June 1396:30 June 1362:8 April 1106:2 April 1054:9 April 887:aspirin 859:colitis 631:153.137 596:Formula 429:DB00244 375:PubChem 364:89-57-6 239:: 200:) 194: ( 192:A07EC02 155: C 126::  102:a688021 21:Aspirin 4987:Portal 4903:Others 4752:HQL-79 4656:SC-560 4651:SC-236 4616:NS-398 3817:Enzyme 3459:EP-045 3424:13-APA 3364:TP (TX 3300:NS-304 3260:AFP-07 2387:WHO-EM 2095:Kaolin 2090:Pectin 1757:  1747:  1699:  1672:  1662:  1594:  1557:  1534:  1524:  1303:  1252:17 May 1226:17 May 899:moiety 865:, and 811:  770:, and 674:SMILES 520:ChEMBL 489:D00377 266:℞-only 264: 251: 241:℞-only 227: 177:rectal 122:  3542:S-145 3391:I-BOP 3236:IP (I 3139:FP (F 2665:EP (E 2484:DP (D 1592:S2CID 1420:(FDA) 1416:U.S. 1386:(FDA) 1382:U.S. 1356:(FDA) 1272:(PDF) 1165:(emc) 741:5-ASA 694:InChI 640:JSmol 500:ChEBI 4803:TXAS 4761:PGFS 4742:PGES 3840:PTGS 1860:and 1810:2020 1784:2020 1755:PMID 1708:2022 1697:PMID 1670:PMID 1644:mBio 1625:2016 1555:ISBN 1532:PMID 1487:2024 1462:2024 1432:2023 1398:2023 1364:2019 1301:ISBN 1254:2022 1228:2022 1202:2019 1173:2019 1136:2024 1108:2024 1082:2024 1056:2023 1030:2019 941:and 933:and 835:and 790:and 778:and 751:and 480:KEGG 460:UNII 449:3933 409:2700 389:4075 287:data 78:AHFS 65:USAN 4780:PGI 4697:PGD 3835:COX 2163:BBB 1866:A07 1745:PMC 1735:doi 1660:PMC 1652:doi 1584:doi 1522:PMC 1514:doi 1329:hdl 901:of 735:or 545:EPA 379:CID 253:POM 197:WHO 5013:: 4728:, 4724:, 4527:; 4455:; 4418:; 4406:; 4389:; 4377:; 4360:; 4318:; 4291:; 4244:; 4102:; 3940:; 3366:A2 3203:2α 3141:2α 3112:2α 2982:EP 2867:EP 2790:EP 2683:EP 2559:DP 2502:DP 2400:: 1853:, 1800:. 1775:. 1753:. 1743:. 1731:24 1729:. 1725:. 1691:. 1668:. 1658:. 1648:12 1646:. 1642:. 1604:^ 1590:. 1580:19 1578:. 1530:. 1520:. 1510:10 1508:. 1504:. 1478:. 1452:. 1448:. 1414:. 1380:. 1351:. 1284:^ 1274:. 1244:. 1218:. 1192:. 1181:^ 1163:. 1144:^ 1124:. 1098:. 1072:. 1046:. 1020:. 1002:. 971:^ 921:. 889:. 869:. 861:, 846:. 798:. 766:, 272:EU 260:US 247:UK 236:CA 229:S4 223:AU 175:, 151:AU 119:US 69:US 4989:: 4948:2 4940:2 4784:S 4782:2 4732:) 4720:( 4701:S 4699:2 4601:) 4599:2 3842:) 3838:( 3825:) 3821:( 3526:2 3398:2 3385:2 3368:) 3316:1 3307:2 3240:) 3238:2 3195:2 3143:) 3074:2 3021:2 3012:1 2984:4 2944:2 2935:1 2927:2 2869:3 2829:2 2820:1 2792:2 2742:2 2733:1 2685:1 2669:) 2667:2 2584:2 2561:2 2522:2 2504:1 2488:) 2486:2 2474:) 2470:( 2444:e 2437:t 2430:v 2199:) 2195:( 2174:) 2170:( 2165:: 2139:) 2135:( 2126:) 2122:( 1868:) 1843:e 1836:t 1829:v 1812:. 1786:. 1761:. 1737:: 1710:. 1676:. 1654:: 1627:. 1598:. 1586:: 1563:. 1538:. 1516:: 1489:. 1464:. 1434:. 1400:. 1366:. 1331:: 1309:. 1256:. 1230:. 1204:. 1175:. 1138:. 1110:. 1084:. 1058:. 1032:. 739:( 642:) 619:3 616:O 613:N 610:7 607:H 604:7 601:C 547:) 543:( 274:: 262:: 249:: 225:: 153:: 80:/ 72:)

Index

Aspirin

Trade names
USAN
AHFS
Drugs.com
Monograph
MedlinePlus
a688021
License data
DailyMed
Mesalamine
Pregnancy
category

Routes of
administration

By mouth
rectal
ATC code
A07EC02
WHO
Legal status
S4
℞-only
POM
℞-only
Pharmacokinetic
Bioavailability
Metabolism
Elimination half-life
IUPAC name
CAS Number

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