43:, a form of congenital hypofibrinogenemia in which specific hereditary mutations in fibrinogen cause it to accumulate in, and damage, liver cells. The disorder may lead to abnormal bleeding and thrombosis but also to
73:(i.e. wrong amount of sugar residues) added to an otherwise normal fibrinogen. The incorrectly glycosalated fibrinogen is dysfunctional and may cause pathological episodes of bleeding and/or blood clotting.
69:, a disorder in which normal levels of fibrinogen are composed at least in part of a dysfunctional fibrinogen due to an acquired disorder (e.g. liver disease) that leads to the synthesis of an incorrectly
172:
Casini A, Sokollik C, Lukowski SW, Lurz E, Rieubland C, de
Moerloose P, Neerman-Arbez M (2015). "Hypofibrinogenemia and liver disease: a new case of Aguadilla fibrinogen and review of the literature".
53:, an inherited disorder in which normal levels of fibrinogen composed at least in part of a dysfunctional fibrinogen may cause abnormal bleeding and thrombosis.
37:, an inherited disorder in which blood may not clot normally due to reduced levels of fibrinogen; the disorder may cause abnormal bleeding and thrombosis.
31:, an inherited blood disorder in which blood does not clot normally due to the lack of fibrinogen; the disorder causes abnormal bleeding and thrombosis.
215:
Casini A, Neerman-Arbez M, Ariëns RA, de
Moerloose P (2015). "Dysfibrinogenemia: from molecular anomalies to clinical manifestations and management".
360:"Genetics, diagnosis and clinical features of congenital hypodysfibrinogenemia: a systematic literature review and report of a novel mutation"
59:, a form of dysfibrinogenemia in which certain fibrinogen mutations cause blood fibrinogen to accumulate in the kidney and cause one type of
89:, an acquired disorder in which fibrinogen precipitates at cold temperatures and may lead to the intravascular precipitation of fibrinogen,
83:
levels of fibrinogen composed at least in part of a dysfunctional fibrinogen may cause pathological episodes of bleeding or blood clotting.
40:
56:
129:
Casini A, de
Moerloose P, Neerman-Arbez M (2016). "Clinical Features and Management of Congenital Fibrinogen Deficiencies".
16:
Fibrinogen disorders are a set of hereditary or acquired abnormalities in the quantity and/or quality of circulating
66:
258:
Gillmore JD, Lachmann HJ, Rowczenio D, Gilbertson JA, Zeng CH, Liu ZH, Li LS, Wechalekar A, Hawkins PN (2009).
34:
24:
or the deposition of fibrinogen in the liver, kidneys, or other organs and tissues. These disorders include:
456:
60:
28:
260:"Diagnosis, pathogenesis, treatment, and prognosis of hereditary fibrinogen A alpha-chain amyloidosis"
400:
76:
107:
8:
358:
Casini A, Brungs T, Lavenu-Bombled C, Vilar R, Neerman-Arbez M, de
Moerloose P (2017).
335:
308:
284:
259:
240:
197:
154:
86:
433:
381:
340:
289:
232:
189:
146:
50:
244:
201:
158:
423:
415:
371:
330:
320:
279:
271:
224:
181:
138:
401:"Clinical conditions responsible for hyperviscosity and skin ulcers complications"
21:
450:
70:
437:
385:
344:
293:
275:
236:
193:
150:
142:
428:
325:
94:
17:
419:
376:
359:
228:
185:
63:; the disorder is not associated with abnormal bleeding or thrombosis.
214:
44:
257:
357:
128:
90:
171:
20:. The disorders may lead to pathological bleeding and/or
399:
Caimi G, Canino B, Lo Presti R, Urso C, Hopps E (2017).
398:
93:, and other circulating proteins thereby causing the
309:"Acquired hypofibrinogenemia: current perspectives"
448:
306:
124:
122:
264:Journal of the American Society of Nephrology
392:
351:
300:
251:
208:
165:
119:
408:Clinical Hemorheology and Microcirculation
97:of various tissues and bodily extremities.
57:Hereditary fibrinogen Aα-Chain amyloidosis
427:
375:
334:
324:
283:
449:
364:Journal of Thrombosis and Haemostasis
217:Journal of Thrombosis and Haemostasis
131:Seminars in Thrombosis and Hemostasis
13:
14:
468:
79:, an inherited disorder in which
307:Besser MW, MacDonald SG (2016).
77:Congenital hypodysfibrinogenemia
108:Fibrinogen#Fibrinogen disorders
1:
113:
35:Congenital hypofibrinogenemia
51:Congenital dysfibrinogenemia
7:
101:
10:
473:
67:Acquired dysfibrinogenemia
61:familial renal amyloidosis
41:Fibrinogen storage disease
29:Congenital afibrinogenemia
313:Journal of Blood Medicine
276:10.1681/ASN.2008060614
143:10.1055/s-0036-1571339
326:10.2147/JBM.S90693
87:Cryofibrinogenemia
457:Lists of diseases
420:10.3233/CH-160218
377:10.1111/jth.13655
229:10.1111/jth.12916
186:10.1111/hae.12719
464:
442:
441:
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170:
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127:
120:
116:
104:
12:
11:
5:
470:
460:
459:
444:
443:
391:
370:(5): 876–888.
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250:
207:
164:
117:
115:
112:
111:
110:
103:
100:
99:
98:
84:
74:
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54:
48:
38:
32:
22:blood clotting
9:
6:
4:
3:
2:
469:
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337:
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273:
270:(2): 444–51.
269:
265:
261:
254:
246:
242:
238:
234:
230:
226:
223:(6): 909–19.
222:
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199:
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187:
183:
179:
175:
168:
160:
156:
152:
148:
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137:(4): 366–74.
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125:
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109:
106:
105:
96:
92:
88:
85:
82:
78:
75:
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46:
42:
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36:
33:
30:
27:
26:
25:
23:
19:
429:10447/238851
414:(1): 25–34.
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407:
394:
367:
363:
353:
316:
312:
302:
267:
263:
253:
220:
216:
210:
180:(6): 820–7.
177:
173:
167:
134:
130:
80:
71:glycosylated
15:
319:: 217–225.
174:Haemophilia
18:fibrinogens
114:References
95:infarction
45:cirrhosis
451:Category
438:28550239
386:28211264
345:27713652
294:19073821
245:10955092
237:25816717
202:44911581
194:25990487
159:12038872
151:27019462
102:See also
336:5045218
285:2637055
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91:fibrin
404:(PDF)
241:S2CID
198:S2CID
155:S2CID
434:PMID
382:PMID
341:PMID
290:PMID
233:PMID
190:PMID
147:PMID
424:hdl
416:doi
372:doi
331:PMC
321:doi
280:PMC
272:doi
225:doi
182:doi
139:doi
81:low
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121:^
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