Knowledge

Lhermitte's sign

Source 📝

697:
Lhermitte JJ, Bollak NM (1924). "Les douleurs à type décharge électrique consécutives à la flexion céphalique dans la sclérose en plaques. Un cas de la sclérose multiple" [Electric shock-like pain resulting from cephalic flexion in multiple sclerosis. A case of multiple sclerosis].
214:
Delayed onset Lhermittes sign has been reported following head and/or neck trauma. This occurs ~2 1/2 months following injury, without associated neurological symptoms or pain, and typically resolves within 1 year.
265:, a French neurologist and neuropsychiatrist, did not publish his first report until 1920. However, in 1924 he did publish the seminal article on the subject which resulted in it becoming well known. 646:
Marie P, Chatelin C (1917). "Sur certains symptÎmes vraisemblablement d'origine radiculaire chez les blessés du crùne" [On certain symptoms presumably of root origin in skull injuries].
281: 734: 234:. Typically, it only occurs after having taken the medication for some duration, and then stopped or withdrawn rapidly or after administering reduced dose. 148:
The sign suggests a lesion or compression of the upper cervical spinal cord or lower brainstem—usually dorsal columns of the cervical cord or caudal
400: 727: 180: 122:, is an uncomfortable "electrical" sensation that runs down the back and into the limbs. The sensation can feel like it goes up or down the 1071: 720: 238:, given its very long half-life, can be given as a single small dose, and often avoid Lhermitte's sign and other withdrawal symptoms. 574: 535:
Chan RC.; Steinbock P. (1984). "Delayed onset of Lhermitte's sign following head and/or neck injuries. Report of four cases".
669: 129:
In many people, it is elicited by bending the head forward. It can also be evoked when a practitioner pounds on the
241:
In the dental field, three studies (Layzer 1978, Gutmann 1979, Blanco 1983) have identified Lhermitte sign among
1000: 196: 848: 223: 219: 1076: 371: 862: 763: 712: 836: 758: 451:"Severe neuropathy after high dose carboplatin in three patients receiving multidrug chemotherapy" 1010: 184: 168: 102: 966: 773: 295: 192: 80: 98: 830: 611: 394: 933: 8: 912: 886: 624: 513: 160: 94: 207:
may also evoke it as an early delayed radiation injury, which occurs within 4 months of
1005: 917: 743: 674: 475: 450: 347: 322: 156: 130: 90: 572:
Roy R. Reeves; Harold B. Pinkofsky (1996). "Lhermitte sign in paroxetine withdrawal".
498:
Frank H. Anderson; James R. Lehrich (1973). "Lhermitte's sign following head injury".
960: 803: 798: 628: 591: 587: 554: 517: 480: 431: 352: 208: 149: 164: 1026: 995: 793: 788: 683: 620: 583: 546: 509: 470: 462: 423: 342: 334: 123: 46: 133:
while the neck is flexed; this is caused by involvement of the posterior columns.
977: 972: 907: 427: 126:. It is painful for some, although others might simply feel strange sensations. 902: 747: 665: 550: 500: 262: 204: 137: 257:
Lhermitte sign is not attributed to its discoverer. It was first described by
249:
leading to a very severe, rapid deficiency in the absence of supplementation.
1065: 1042: 808: 338: 242: 435: 258: 200: 632: 595: 558: 521: 484: 466: 356: 813: 609:
José A. Gutrecht (1989). "Lhermitte's sign: from observation to eponym".
537: 231: 188: 176: 86: 235: 227: 222:" associated with certain psychotropic medications, such as selective 172: 742: 111: 245:
abusers. This is likely due to nitrous oxide depletion of vitamin B
497: 199:. Lhermitte's sign may also appear during or following high-dose 571: 16:
Uncomfortable "electric" sensation going down the back and limbs
871: 670:"Les Formes douloureuses de la Commotion de la Moelle épiniére" 369: 226:
and serotonin norepinephrine reuptake inhibitors, particularly
61: 52: 136:
Lhermitte phenomenon is named after the French neurologist
682:(3). SociĂ©tĂ© Française de Neurologie: 257–262 – via 448: 159:, it can be caused by a number of conditions, including 696: 414:
JONES, A (Oct 1964). "Transient Radiation Myelopathy".
370:
Steiner, R. D., & Basel, D. (December 12, 2019).
534: 64: 49: 672:[Painful Forms of Spinal Cord Concussion]. 645: 58: 55: 455:Journal of Neurology, Neurosurgery, and Psychiatry 1063: 608: 658: 327:British Medical Journal (Clinical Research Ed.) 320: 218:This sign is also sometimes seen as part of a " 155:Although often considered a classic finding in 449:Heinzlef, O; Lotz, JP; Roullet, E (May 1998). 728: 399:: CS1 maint: multiple names: authors list ( 187:in the neck from any cause such as cervical 735: 721: 664: 474: 346: 143: 1064: 575:Journal of Clinical Psychopharmacology 716: 413: 321:Page, NG; Spiteri, MA (Mar 6, 1982). 625:10.1001/archneur.1989.00520410091029 514:10.1001/archneur.1973.00490300099015 300:medterms medical dictionary a-z list 781: 13: 1072:Symptoms and signs: Nervous system 372:"COL1A1/2 Osteogenesis Imperfecta" 323:"Lhermitte sign in Behçet disease" 282:"Lhermitte's sign | MS Trust" 14: 1088: 588:10.1097/00004714-199610000-00013 416:The British Journal of Radiology 45: 690: 639: 602: 565: 528: 491: 442: 407: 363: 314: 296:"Definition of Lhermitte sign" 288: 274: 252: 185:compression of the spinal cord 181:subacute combined degeneration 1: 268: 224:serotonin reuptake inhibitors 428:10.1259/0007-1285-37-442-727 7: 120:the barber chair phenomenon 10: 1093: 849:Charcot's neurologic triad 551:10.3171/jns.1984.60.3.0609 197:Arnold–Chiari malformation 1035: 1019: 988: 953: 946: 926: 895: 879: 870: 863:Peripheral nervous system 861: 822: 772: 764:Cranial nerve examination 754: 85:Compression of the upper 79: 37: 29: 24: 759:Neurological examination 339:10.1136/bmj.284.6317.704 220:discontinuation syndrome 169:osteogenesis imperfecta 103:osteogenesis imperfecta 967:carpal tunnel syndrome 774:Central nervous system 261:and Chatelin in 1917. 203:. Irradiation of the 81:Differential diagnosis 831:Intracranial pressure 612:Archives of Neurology 467:10.1136/jnnp.64.5.667 144:Associated conditions 1011:Trendelenburg's sign 171:, trauma, radiation 116:Lhermitte phenomenon 33:Lhermitte phenomenon 25:Lhermitte's sign 887:Jendrassik maneuver 161:transverse myelitis 95:transverse myelitis 1077:Multiple sclerosis 1006:Straight leg raise 744:Signs and symptoms 700:Revue neurologique 675:Revue neurologique 648:Revue Neurologique 157:multiple sclerosis 91:multiple sclerosis 1059: 1058: 1055: 1054: 1051: 1050: 942: 941: 934:Hoffmann's reflex 857: 856: 302:. MedicineNet.com 209:radiation therapy 108: 107: 19:Medical condition 1084: 951: 950: 913:Oppenheim's sign 877: 876: 868: 867: 844:Lhermitte's sign 779: 778: 746:relating to the 737: 730: 723: 714: 713: 708: 707: 694: 688: 687: 684:Internet Archive 668:(4 March 1920). 666:Lhermitte, J. J. 662: 656: 655: 643: 637: 636: 606: 600: 599: 569: 563: 562: 532: 526: 525: 495: 489: 488: 478: 446: 440: 439: 411: 405: 404: 398: 390: 388: 386: 376: 367: 361: 360: 350: 318: 312: 311: 309: 307: 292: 286: 285: 278: 99:Behçet's disease 71: 70: 67: 66: 63: 60: 57: 54: 51: 22: 21: 1092: 1091: 1087: 1086: 1085: 1083: 1082: 1081: 1062: 1061: 1060: 1047: 1031: 1015: 984: 978:Phalen maneuver 938: 922: 918:Westphal's sign 908:Chaddock reflex 891: 853: 837:Cushing's triad 818: 768: 750: 741: 711: 695: 691: 663: 659: 644: 640: 607: 603: 570: 566: 533: 529: 496: 492: 447: 443: 422:(442): 727–44. 412: 408: 392: 391: 384: 382: 374: 368: 364: 333:(6317): 704–5. 319: 315: 305: 303: 294: 293: 289: 280: 279: 275: 271: 255: 248: 193:disc herniation 146: 75: 48: 44: 20: 17: 12: 11: 5: 1090: 1080: 1079: 1074: 1057: 1056: 1053: 1052: 1049: 1048: 1046: 1045: 1039: 1037: 1033: 1032: 1030: 1029: 1023: 1021: 1017: 1016: 1014: 1013: 1008: 1003: 998: 992: 990: 986: 985: 983: 982: 981: 980: 975: 963: 961:Froment's sign 957: 955: 948: 944: 943: 940: 939: 937: 936: 930: 928: 924: 923: 921: 920: 915: 910: 905: 903:Plantar reflex 899: 897: 893: 892: 890: 889: 883: 881: 874: 865: 859: 858: 855: 854: 852: 851: 846: 841: 840: 839: 826: 824: 820: 819: 817: 816: 811: 806: 804:Myerson's sign 801: 799:Macewen's sign 796: 791: 785: 783: 776: 770: 769: 767: 766: 761: 755: 752: 751: 748:nervous system 740: 739: 732: 725: 717: 710: 709: 689: 657: 638: 619:(5): 557–558. 601: 582:(5): 411–412. 564: 527: 501:JAMA Neurology 490: 441: 406: 362: 313: 287: 272: 270: 267: 263:Jean Lhermitte 254: 251: 246: 205:cervical spine 165:Behçet disease 145: 142: 138:Jean Lhermitte 131:cervical spine 118:, also called 106: 105: 83: 77: 76: 74: 73: 41: 39: 35: 34: 31: 27: 26: 18: 15: 9: 6: 4: 3: 2: 1089: 1078: 1075: 1073: 1070: 1069: 1067: 1044: 1043:Pain stimulus 1041: 1040: 1038: 1034: 1028: 1027:Beevor's sign 1025: 1024: 1022: 1018: 1012: 1009: 1007: 1004: 1002: 1001:Hoover's sign 999: 997: 996:Gowers's sign 994: 993: 991: 987: 979: 976: 974: 971: 970: 969: 968: 964: 962: 959: 958: 956: 952: 949: 945: 935: 932: 931: 929: 925: 919: 916: 914: 911: 909: 906: 904: 901: 900: 898: 894: 888: 885: 884: 882: 878: 875: 873: 869: 866: 864: 860: 850: 847: 845: 842: 838: 835: 834: 833: 832: 828: 827: 825: 821: 815: 812: 810: 807: 805: 802: 800: 797: 795: 794:Kernig's sign 792: 790: 789:Battle's sign 787: 786: 784: 780: 777: 775: 771: 765: 762: 760: 757: 756: 753: 749: 745: 738: 733: 731: 726: 724: 719: 718: 715: 705: 702:(in French). 701: 693: 685: 681: 678:(in French). 677: 676: 671: 667: 661: 653: 650:(in French). 649: 642: 634: 630: 626: 622: 618: 614: 613: 605: 597: 593: 589: 585: 581: 577: 576: 568: 560: 556: 552: 548: 545:(3): 609–12. 544: 540: 539: 531: 523: 519: 515: 511: 507: 503: 502: 494: 486: 482: 477: 472: 468: 464: 460: 456: 452: 445: 437: 433: 429: 425: 421: 417: 410: 402: 396: 380: 373: 366: 358: 354: 349: 344: 340: 336: 332: 328: 324: 317: 301: 297: 291: 283: 277: 273: 266: 264: 260: 250: 244: 243:nitrous oxide 239: 237: 233: 229: 225: 221: 216: 212: 210: 206: 202: 198: 195:, tumor, and 194: 190: 186: 182: 178: 174: 170: 166: 162: 158: 153: 151: 141: 139: 134: 132: 127: 125: 121: 117: 113: 104: 100: 96: 92: 88: 84: 82: 78: 69: 43: 42: 40: 38:Pronunciation 36: 32: 28: 23: 973:Tinel's sign 965: 843: 829: 703: 699: 692: 679: 673: 660: 651: 647: 641: 616: 610: 604: 579: 573: 567: 542: 536: 530: 508:(6): 437–8. 505: 499: 493: 461:(5): 667–9. 458: 454: 444: 419: 415: 409: 395:cite journal 383:. Retrieved 378: 365: 330: 326: 316: 304:. Retrieved 299: 290: 276: 259:Pierre Marie 256: 240: 217: 213: 201:chemotherapy 179:deficiency ( 154: 147: 135: 128: 119: 115: 109: 880:Combination 814:Hirano body 809:Stroop test 538:J Neurosurg 385:February 4, 379:GeneReviews 253:Terminology 232:venlafaxine 189:spondylosis 177:vitamin B12 87:spinal cord 30:Other names 1066:Categories 269:References 236:Fluoxetine 228:paroxetine 173:myelopathy 112:neurology 872:Reflexes 706:: 56–57. 436:14217730 306:20 April 1036:General 633:2653292 596:8889917 559:6699706 522:4759419 485:9598687 476:2170092 357:6802294 348:1496643 150:medulla 654:: 336. 631:  594:  557:  520:  483:  473:  434:  381:: 1–29 355:  345:  72: 1020:Torso 947:Other 823:Other 375:(PDF) 124:spine 989:Legs 954:Arms 927:Arms 896:Legs 782:Head 629:PMID 592:PMID 555:PMID 518:PMID 481:PMID 432:PMID 401:link 387:2020 353:PMID 308:2011 230:and 621:doi 584:doi 547:doi 510:doi 471:PMC 463:doi 424:doi 343:PMC 335:doi 331:284 183:), 110:In 53:ɛər 1068:: 680:36 652:31 627:. 617:46 615:. 590:. 580:16 578:. 553:. 543:60 541:. 516:. 506:29 504:. 479:. 469:. 459:64 457:. 453:. 430:. 420:37 418:. 397:}} 393:{{ 377:. 351:. 341:. 329:. 325:. 298:. 247:12 211:. 191:, 175:, 167:, 163:, 152:. 140:. 114:, 101:, 97:, 93:, 89:, 62:iː 736:e 729:t 722:v 704:2 686:. 635:. 623:: 598:. 586:: 561:. 549:: 524:. 512:: 487:. 465:: 438:. 426:: 403:) 389:. 359:. 337:: 310:. 284:. 68:/ 65:t 59:m 56:ˈ 50:l 47:/

Index

/lɛərˈmiːt/
Differential diagnosis
spinal cord
multiple sclerosis
transverse myelitis
Behçet's disease
osteogenesis imperfecta
neurology
spine
cervical spine
Jean Lhermitte
medulla
multiple sclerosis
transverse myelitis
Behçet disease
osteogenesis imperfecta
myelopathy
vitamin B12
subacute combined degeneration
compression of the spinal cord
spondylosis
disc herniation
Arnold–Chiari malformation
chemotherapy
cervical spine
radiation therapy
discontinuation syndrome
serotonin reuptake inhibitors
paroxetine
venlafaxine

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.

↑