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Houra Merrikh

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Her work researches ways to slow the rate of bacterial mutations and to block their evolution. In 2017, she led the research group to help bacteria survive hostile environments and resist antibiotics, done through disrupting
136:, 2016 Vilcek Prize for Creative Promise in Biomedical Science, and the University of Washington Innovation Award in 2015 for her research on the impact of replication-transcription conflicts on 128:
Merrikh is one of the recipients of the 2013 National Institutes of Health (NIH) Director’s New Innovator Awards, for investigating the impact of replication-transcription conflicts on
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Her research into the mutagenic nature of co-directional gene collisions were revolutionary in the field and won her the 2016 Vilcek Prize for Creative Promise in Biomedical Science.
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Lang, Kevin S.; Hall, Ashley N.; Merrikh, Christopher N.; Ragheb, Mark; Tabakh, Hannah; Pollock, Alex J.; Woodward, Joshua J.; Dreifus, Julia E.; Merrikh, Houra (August 2017).
536: 108:(Mfd) quickens the bacterial mutation process. In January 2019, she was appointed full Professor in the Department of Biochemistry at Vanderbilt University. 699: 972: 57:
to continue her education. She naturalized as a citizen of the United States in 2003. After attending community college in Texas, she enrolled at the
451: 977: 967: 1012: 1002: 648: 477:"How head-on collisions of DNA protein machines stop replication: The collisions promote mutations that may help bacteria adapt to stress" 726: 992: 982: 566: 1007: 997: 987: 947: 887: 502: 957: 418: 89: 826: 962: 751: 622: 932: 673: 952: 942: 927: 801: 922: 358:"Replication-transcription conflicts generate R-loops that orchestrate bacterial stress survival and pathogenesis" 937: 303:
Merrikh, Houra; Ferrazzoli, Alexander E.; Bougdour, Alexandre; Olivier-Mason, Anique; Lovett, Susan T. (2009).
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In 2009, she was appointed Assistant Professor of Microbiology in the Department of Health and Sciences at the
752:"Project Information - NIH RePORTER - NIH Research Portfolio Online Reporting Tools Expenditures and Results" 157:
Merrikh, Houra; MachĂłn, Cristina; Grainger, William H.; Grossman, Alan D.; Soultanas, Panos (February 2011).
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in the Department of Biochemistry. Her field of work is antibiotic resistance and bacterial evolvability.
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Paul, Sandip; Million-Weaver, Samuel; Chattopadhyay, Sujay; Sokurenko, Evgeni; Merrikh, Houra (2013).
777:"The Vilcek Foundation - The Vilcek Foundation - 2016 Vilcek Prize in Biomedical Science and Theatre" 877: 872: 137: 101: 476: 129: 776: 917: 863: 133: 58: 30: 316: 265: 170: 73: 868: 8: 700:""Anti-Evolution Drugs" Could Offer New Strategy against Antimicrobial Resistance Crisis" 77: 320: 305:"A DNA damage response in Escherichia coli involving the alternative sigma factor, RpoS" 269: 174: 382: 357: 339: 304: 286: 253: 235: 210: 191: 158: 902: 880:
from National Center for Biotechnology Information, U.S. National Library of Medicine
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Her most cited publications after the award of her doctorate are, according to
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Houra Merrikh 2016 Vilcek Prize for Creative Promise in Biomedical Science
853: 567:"GSA member Houra Merrikh honored with Vilcek Prize for Creative Promise" 898: 419:"Houra Merrikh on Overcoming Adversity and Becoming a Leading Scientist" 277: 254:"Accelerated gene evolution through replication–transcription conflicts" 251: 226: 182: 302: 209:
Merrikh, Houra; Zhang, Yan; Grossman, Alan D.; Wang, Jue D. (2012).
117: 727:"How DNA Protein Machines Collide Head on and Stop Replication" 50: 537:"Trump's Immigration Ban Is Already Harming American Science" 156: 54: 42: 649:"Merrikh Lab Working to Defeat Drug-Resistant Superbugs" 452:"A Bold New Strategy for Stopping the Rise of Superbugs" 208: 355: 104:. In 2015, she discovered a bacterial protein called 16:
Iranian American microbiologist, biochemist, educator
583:Working with former GSA Board member Susan Lovett 211:"Replication–transcription conflicts in bacteria" 909: 704:GEN - Genetic Engineering and Biotechnology News 412: 410: 408: 309:Proceedings of the National Academy of Sciences 802:"14 UW researchers win 2015 Innovation Awards" 623:"Bacteria Sacrifice DNA Repair for Better RNA" 894:episode 13, from Everything You Know is Wrong 405: 36: 169:(7335). Nature Publishing Group: 554–557. 973:Naturalized citizens of the United States 724: 381: 338: 328: 285: 234: 190: 416: 264:(7442). Nature Publishing Group: 512–5. 646: 221:(7). Nature Publishing Group: 449–458. 978:21st-century American women scientists 968:Iranian emigrants to the United States 910: 620: 1013:21st-century Iranian women scientists 1003:20th-century Iranian women scientists 90:Massachusetts Institute of Technology 885:It's in the Genes with Houra Merrikh 731:Science and Technology Research News 653:Science and Technology Research News 561: 559: 557: 534: 503:"It's In the Genes w/ Houra Merrikh" 449: 445: 443: 441: 439: 417:Memarian, Jahandad (June 26, 2016). 123: 871:at the Department of Microbiology, 862:at the Department of Biochemistry, 13: 725:Rasmussen, Ray (August 15, 2017). 666: 647:Palisoc, Mhean (January 3, 2019). 602:. Brandeis University. Winter 2016 14: 1024: 847: 827:"User profiles for Houra Merrikh" 640: 554: 436: 88:(NIH) postdoctoral fellow at the 993:University of Washington faculty 983:21st-century American biologists 45:and fled the country during the 1008:21st-century Iranian scientists 998:20th-century Iranian scientists 819: 794: 769: 744: 718: 692: 143: 680:(in French). December 31, 2018 614: 588: 528: 495: 469: 450:Yong, Ed (November 15, 2018). 116:in order to boost the rate of 1: 988:Vanderbilt University faculty 948:Iranian expatriates in Turkey 535:Yong, Ed (January 29, 2017). 399: 86:National Institutes of Health 53:. At age 16, she was sent to 29:. She is a full professor at 958:University of Houston alumni 507:Everything You Know Is Wrong 92:(MIT) from 2009 until 2011. 80:, and worked with biologist 7: 215:Nature Reviews Microbiology 10: 1029: 963:Brandeis University alumni 596:"Graduate Students: 2000s" 374:10.1016/j.cell.2017.07.044 368:(4). Cell Press: 787–799. 106:Mutation Frequency Decline 933:American women biologists 890:October 22, 2019, at the 95: 953:Boston University alumni 943:Iranian women scientists 928:American microbiologists 873:University of Washington 856:at Vanderbilt University 102:University of Washington 37:Early life and education 923:Iranian microbiologists 869:Houra Merrikh's profile 756:projectreporter.nih.gov 330:10.1073/pnas.0803665106 938:Women microbiologists 864:Vanderbilt University 860:Houra Merrikh profile 621:Cepelewicz, Jordana. 138:antibiotic resistance 72:degree in 2006 and a 59:University of Houston 31:Vanderbilt University 878:Merrikh, H. articles 49:, she was raised in 41:Merrikh was born in 706:. November 19, 2018 513:on October 22, 2019 321:2009PNAS..106..611M 278:10.1038/nature11989 270:2013Natur.495..512P 227:10.1038/nrmicro2800 183:10.1038/nature09758 175:2011Natur.470..554M 132:. She received the 130:bacterial evolution 78:Brandeis University 903:Vilcek Foundation 600:Brandeis Magazine 483:. August 15, 2017 205:(Cited 132 times) 134:Vilcek Foundation 124:Honors and awards 63:Boston University 1020: 842: 841: 839: 837: 823: 817: 816: 814: 812: 798: 792: 791: 789: 787: 773: 767: 766: 764: 762: 748: 742: 741: 739: 737: 722: 716: 715: 713: 711: 696: 690: 689: 687: 685: 670: 664: 663: 661: 659: 644: 638: 637: 635: 633: 618: 612: 611: 609: 607: 592: 586: 585: 580: 578: 571:Genes to Genomes 563: 552: 551: 549: 547: 532: 526: 525: 520: 518: 509:. 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Retrieved 830: 821: 809:. Retrieved 805: 796: 784:. Retrieved 780: 771: 759:. Retrieved 755: 746: 734:. Retrieved 730: 720: 708:. Retrieved 703: 694: 682:. Retrieved 677: 668: 656:. Retrieved 652: 642: 630:. Retrieved 626: 616: 604:. Retrieved 599: 590: 582: 575:. Retrieved 570: 544:. Retrieved 541:The Atlantic 540: 530: 522: 515:. Retrieved 511:the original 506: 497: 485:. Retrieved 481:ScienceDaily 480: 471: 459:. Retrieved 456:The Atlantic 455: 426:. Retrieved 422: 365: 361: 312: 308: 261: 257: 218: 214: 166: 162: 147: 144:Publications 127: 110: 99: 84:. She was a 82:Susan Lovett 67: 40: 19: 18: 854:Merrikh Lab 736:October 22, 710:October 22, 684:October 22, 658:October 22, 632:October 22, 606:October 22, 577:October 22, 546:October 22, 517:October 22, 487:October 22, 461:October 22, 912:Categories 400:References 61:and later 883:Podcast: 811:March 26, 786:March 26, 761:March 26, 428:March 26, 888:Archived 678:Slate.fr 392:28802046 349:19124769 296:23538833 245:22669220 201:21350489 897:Video: 806:UW News 383:5630229 340:2626751 317:Bibcode 287:3807732 266:Bibcode 236:3467967 192:3059490 171:Bibcode 390:  380:  347:  337:  294:  284:  258:Nature 243:  233:  199:  189:  163:Nature 96:Career 51:Turkey 22:is an 74:Ph.D. 55:Texas 838:2019 813:2018 788:2018 763:2018 738:2019 712:2019 686:2019 660:2019 634:2019 608:2019 579:2019 548:2019 519:2019 489:2019 463:2019 430:2018 388:PMID 362:Cell 345:PMID 292:PMID 241:PMID 197:PMID 70:M.S. 43:Iran 378:PMC 370:doi 366:170 335:PMC 325:doi 313:106 282:PMC 274:doi 262:495 231:PMC 223:doi 187:PMC 179:doi 167:470 914:: 829:. 804:. 779:. 754:. 729:. 702:. 676:. 651:. 625:. 598:. 581:. 569:. 556:^ 539:. 521:. 505:. 479:. 454:. 438:^ 421:. 407:^ 386:. 376:. 364:. 360:. 343:. 333:. 323:. 311:. 307:. 290:. 280:. 272:. 260:. 256:. 239:. 229:. 219:10 217:. 213:. 195:. 185:. 177:. 165:. 161:. 152:: 120:. 65:. 840:. 815:. 790:. 765:. 740:. 714:. 688:. 662:. 636:. 610:. 550:. 491:. 465:. 432:. 394:. 372:: 351:. 327:: 319:: 298:. 276:: 268:: 247:. 225:: 203:. 181:: 173::

Index

Iranian-American
microbiologist
Vanderbilt University
Iran
Iran-Iraq War
Turkey
Texas
University of Houston
Boston University
M.S.
Ph.D.
Brandeis University
Susan Lovett
National Institutes of Health
Massachusetts Institute of Technology
University of Washington
Mutation Frequency Decline
DNA replication
gene mutations
bacterial evolution
Vilcek Foundation
antibiotic resistance
Google Scholar
"Co-directional replication-transcription conflicts lead to replication restart"
Bibcode
2011Natur.470..554M
doi
10.1038/nature09758
PMC
3059490

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