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Gallbladder cancer

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420: 452: 432: 29: 222:, with an incidence of fewer than 2 cases per 100,000 people per year in the United States. It is particularly common in central and South America, central and eastern Europe, Japan and northern India; it is also common in certain ethnic groups e.g. Native American Indians and Hispanics. If it is diagnosed early enough, it can be cured by removing the 261:. Porcelain gallbladder is also rare. Some studies indicate that people with porcelain gallbladder have a high risk of developing gallbladder cancer, but other studies question this. The outlook is poor for recovery if the cancer is found after symptoms have started to occur, with a 5-year survival rate of close to 3%. 506:
may also be used with surgery. If gallbladder cancer is diagnosed after cholecystectomy for stone disease (incidental cancer), re-operation to remove part of liver and lymph nodes is required in most cases. When it is done as early as possible, patients have the best chance of long-term survival and
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states that in the presence of a palpably enlarged gallbladder which is nontender and accompanied with mild painless jaundice, the cause is unlikely to be gallstones. This implicates possible malignancy of the gallbladder or pancreas, and the swelling is unlikely due to gallstones due to the chronic
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in the vicinity are also removed. Sometimes removal of a large part of the liver called hepatectomy is required to completely remove the tumor. The bile duct if involved also needs to be removed. However, with gallbladder cancer's extremely poor prognosis, most patients will die within a year of
576:. The tumors in about 25% of patients with biliary tract cancer have some form of DNA damage repair deficiency. Knowledge of such deficiencies can be exploited to potentially increase response to treatment strategies that are currently available such as 989:
Duffy, A.; Capanu, M.; Abou-Alfa, G. K.; Huitzil, D.; Jarnagin, W.; Fong, Y.; D'Angelica, M.; Dematteo, R. P.; Blumgart, L. H. (2008-12-01). "Gallbladder cancer (GBC): 10-year experience at Memorial Sloan-Kettering Cancer Centre (MSKCC)".
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Lamarca A, Barriuso J, McNamara MG, Valle JW. Biliary Tract Cancer: State of the Art and potential role of DNA Damage Repair. Cancer Treat Rev. 2018 Nov;70:168-177. doi: 10.1016/j.ctrv.2018.09.002. Epub 2018 Sep 8. PMID
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Various single nucleotide polymorphisms (SNPs) have been shown to be associated with gallbladder cancer; however, existing genetic studies in GBC susceptibility have so far been insufficient to confirm any
331:, published in Germany in 1890, were not originally cited as a law, and no mention of malignancy or pain (tenderness) was made. These points are commonly misquoted or confused in the medical literature. 431: 419: 1045: 948:
Srivastava K, Srivastava A, Sharma KL, Mittal B. Candidate gene studies in gallbladder cancer: a systematic review and meta-analysis. Mutat Res. 2011 Jul–Oct;728(1–2):67–79.
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which mimics gallbladder cancer although it is not cancerous. It was first discovered and reported in the medical literature in 1976 by J.J. McCoy Jr., and colleagues.
409:, and MR cholangio-pancreatography (MRCP) can be used for diagnosis. A large number of gallbladder cancers are found incidentally in patients being evaluated for 530:
Gallbladder cancer is more common in South American countries, Japan, and Israel; in Chile, gallbladder cancer is the fourth most common cause of cancer deaths.
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Early diagnosis is not generally possible. People at high risk, such as women or Native Americans with gallstones, are evaluated closely. Transabdominal
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Rao RV, Kumar A, Sikora SS, Saxena R, Kapoor VK (2005). "Xanthogranulomatous cholecystitis: differentiation from associated gall bladder carcinoma".
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If detected early in a stage where it has not spread, gallbladder cancer can be treated by surgery. Surgery for gallbladder cancer is called radical
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or percutaneous transhepatic biliary drainage (PTBD) of the biliary tree can reduce jaundice and a stent in the stomach may relieve vomiting.
413:, or gallstone formation, which is far more common. A biopsy is the only certain way to tell whether or not the tumorous growth is malignant. 1738: 489:
or extended cholecystectomy. It entails the removal of gallbladder along with adequate removal of its liver bed to the healthy tissue. The
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National Cancer Registry Programme (2013).Three-year report of population based cancer registries:2009-2011. NCDIR-ICMR, Bangalore.
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inflammation associated with gallstones leading to a shrunken, non-distensible gallbladder. However, the original observations of
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carriers have 3 to 200 times higher risk of gallbladder cancer than non-carriers and 1–6% lifetime risk of development of cancer
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A better understanding of the biology of biliary tract cancers, including gallbladder cancer, is being achieved by advances in
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McCoy JJ, Vila R, Petrossian G, McCall RA, Reddy KS (March 1976). "Xanthogranulomatous cholecystitis. Report of two cases".
1072:"Xanthogranulomatous cholecystitis mimicking gallbladder carcinoma with a false-positive result on fluorodeoxyglucose PET" 2058: 2037: 1993: 1493: 539:
The age adjusted incidence rates of gallbladder cancer is highest in Chile, followed by in the state of Assam in India
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Fitzgerald, J Edward F; White Matthew J; Lobo Dileep N (Apr 2009). "Courvoisier's gallbladder: law or sign?".
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Folseraas, T; Boberg, KM (February 2016). "Cancer Risk and Surveillance in Primary Sclerosing Cholangitis".
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Gallbladder cancer is relatively rare, affecting fewer than 5000 people in the United States per year
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Early symptoms mimic gallbladder inflammation due to gallstones. Later, the symptoms may be that of
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It is a rare cancer that is thought to be related to gallstones building up, which also can lead to
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Henley, S. Jane; Weir, Hannah K.; Jim, Melissa A.; Watson, Meg; Richardson, Lisa C. (2018-09-27).
572:. This research is providing insight into deficiencies in the tumor cell's ability to accurately 2032: 1781: 1550: 190: 108: 83: 1873: 1661: 1623: 536:
Up to 5 times more common in women than men depending on population (e.g. 73% female in China)
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Gender— approximately twice as common in women than men, usually in seventh and eighth decades
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Henley, S. Jane; Weir, Hannah K.; Jim, Melissa A.; Watson, Meg; Richardson, Lisa C. (2015).
1878: 323: 134: 8: 1446: 495: 474: 1920: 1860: 1689: 1685: 1361: 1334: 1301: 1276: 1098: 1071: 1023: 863: 773: 726: 54: 2005: 1957: 1948: 1671: 1573: 1542: 1468: 1366: 1306: 1257: 1249: 1157: 1130: 1103: 1015: 1007: 965: 929: 898: 855: 847: 806: 765: 718: 503: 174: 141: 36: 1451: 1277:"Gallstones and the risk of biliary tract cancer: a population-based study in China" 1027: 867: 1806: 1680: 1595: 1583: 1356: 1346: 1296: 1288: 1239: 1093: 1083: 999: 921: 890: 839: 757: 710: 368: 294: 160: 41: 777: 761: 730: 714: 698: 1648: 1631: 1462: 647:"Types of gallbladder cancer | Gallbladder cancer | Cancer Research UK" 486: 442: 247: 925: 1962: 1925: 1855: 1753: 1693: 1636: 1565: 1555: 1473: 1245:
10.1002/1097-0142(19950101)75:1+<171::AID-CNCR2820751306>3.0.CO;2-2
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U.S. National Cancer Institute Gallbladder Cancer Treatment (www.cancer.gov)
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Kapoor VK, McMichael AJ (2003). "Gallbladder cancer: an 'Indian' disease".
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The prognosis still remains poor. The cancer commonly spreads to the
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Congenital abnormalities of the bile duct such as choledochal cyst
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Ferreccio, C. (2012). "Salmonella typhi and Gallbladder Cancer".
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Makino I, Yamaguchi T, Sato N, Yasui T, Kita I (August 2009).
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Gallbladder adenocarcinoma lymphatic invasion histopathology
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Hsing AW, Gao YT, Han TQ, et al. (December 2007).
692: 690: 1201:"Gallbladder Cancer Treatment (PDQ®)–Patient Version" 1405: 1120: 746:"CDC - Gallbladder Cancer Incidence and Death Rates" 687: 743: 696: 381:Calcified gallbladder wall (porcelain gallbladder) 146:Blood tests, medical imaging, examination of the 2050: 750:Cancer Epidemiology, Biomarkers & Prevention 703:Cancer Epidemiology, Biomarkers & Prevention 603: 601: 880: 796: 246:and vomiting occur, and it has spread to other 1515: 1382: 1380: 1225: 1501: 1226:Carriaga, M. T.; Henson, D. E. (1995-01-01). 909: 874: 598: 437:Incidentally discovered gallbladder cancer ( 1377: 1274: 1176:"Cholecystectomy: Approaches and Technique" 1065: 1063: 88:Cancer spreading to other parts of the body 78:, although some people may have no symptoms 1508: 1494: 609:"Gallbladder cancer - Symptoms and causes" 27: 1764:Hereditary nonpolyposis colorectal cancer 1360: 1350: 1300: 1243: 1097: 1087: 915: 465: 257:of the gallbladder, a condition known as 1060: 1989:Intraductal papillary mucinous neoplasm 1141: 533:5th most common gastrointestinal cancer 2051: 1332: 473:cholecystitis (XGC) is a rare form of 270:Steady pain in the upper right abdomen 1489: 1114: 960: 958: 956: 954: 629:"Risk Factors for Gallbladder Cancer" 494:surgery. If surgery is not possible, 264: 1180:The Lecturio Medical Concept Library 1048:from the original on 10 October 2011 2038:Desmoplastic small round cell tumor 13: 1739:Polymerase proofreading-associated 1268: 951: 367:infection of gallbladder; chronic 14: 2080: 1601:Hereditary diffuse gastric cancer 1394: 1339:World Journal of Gastroenterology 681:"Gallbladder Cancer - Statistics" 1897:Nodular regenerative hyperplasia 1333:Goetze, T.O (21 November 2015). 450: 430: 418: 1326: 1317: 1219: 1193: 1168: 1034: 982: 942: 574:repair damages in their own DNA 510: 334: 234:. Most often it is found after 1999:Solid pseudopapillary neoplasm 1802:Gastrointestinal stromal tumor 1759:Familial adenomatous polyposis 1042:"Tests for gallbladder cancer" 817: 790: 737: 673: 653: 639: 621: 359:Primary sclerosing cholangitis 1: 1807:Krukenberg tumor (metastatic) 762:10.1158/1055-9965.EPI-15-0199 715:10.1158/1055-9965.EPI-15-0199 591: 519:, with a small percent being 159:Other types of cancer in the 2028:Primary peritoneal carcinoma 1702:traditional serrated adenoma 992:Journal of Surgical Oncology 543: 480: 388: 209:~2,000 deaths per year (USA) 7: 1968:Pancreatic ductal carcinoma 926:10.1007/978-94-007-2585-0_5 563: 457:Gallbladder adenocarcinoma 201:~3,700 cases per year (USA) 70:, Unexplained weight loss, 10: 2085: 2059:Digestive system neoplasia 1984:Serous microcystic adenoma 1579:Signet ring cell carcinoma 1517:Digestive system neoplasia 193:~19% (USA) (January, 2020) 2018: 1947: 1905: 1892:Focal nodular hyperplasia 1828: 1819: 1794: 1772: 1670: 1647: 1622: 1613: 1564: 1541: 1532: 1523: 1409: 1352:10.3748/wjg.v21.i43.12211 1205:National Cancer Institute 895:10.1016/j.cld.2015.08.014 844:10.1007/s00268-008-9908-y 319:and stomach obstruction. 218:is a relatively uncommon 205: 197: 184: 166: 153: 140: 123: 115: 100: 92: 82: 53: 35: 26: 21: 1994:Mucinous cystic neoplasm 1844:Hepatocellular carcinoma 1698:sessile serrated adenoma 883:Clinics in Liver Disease 827:World Journal of Surgery 329:Ludwig Georg Courvoisier 2033:Peritoneal mesothelioma 1782:Squamous cell carcinoma 1551:Squamous cell carcinoma 191:Five-year survival rate 109:Squamous cell carcinoma 1874:Hepatocellular adenoma 1662:Pseudomyxoma peritonei 1293:10.1038/sj.bjc.6604047 1076:World J. Gastroenterol 1044:. Cancer Research UK. 466:Differential diagnosis 155:Differential diagnosis 2064:Gallbladder disorders 259:porcelain gallbladder 76:Yellowing of the skin 1879:Cavernous hemangioma 1730:Familial adenomatous 1717:Polyposis syndromes: 1238:(1 Suppl): 171–190. 920:. pp. 117–137. 135:Gallbladder diseases 1345:(43): 12211–12217. 1089:10.3748/wjg.15.3691 918:Bacteria and Cancer 496:endoscopic stenting 475:gallbladder disease 471:Xanthogranulomatous 250:such as the liver. 1939:Gallbladder cancer 1921:Cholangiocarcinoma 1861:Liver angiosarcoma 1795:Upper and/or lower 1744:Serrated polyposis 1123:Trop Gastroenterol 378:Gallbladder polyps 311:due to obstruction 265:Signs and symptoms 216:Gallbladder cancer 96:Above 65 years old 22:Gallbladder cancer 2046: 2045: 2014: 2013: 2006:Pancreatoblastoma 1958:exocrine pancreas 1815: 1814: 1790: 1789: 1609: 1608: 1574:Gastric carcinoma 1483: 1482: 1004:10.1002/jso.21141 970:Dr.Nikhil Agrawal 935:978-94-007-2584-3 570:genomic profiling 324:Courvoisier's law 213: 212: 175:Radiation therapy 142:Diagnostic method 16:Medical condition 2076: 1826: 1825: 1725:MUTYH-associated 1710:Cronkhite–Canada 1681:Colorectal polyp 1620: 1619: 1596:Linitis plastica 1584:Gastric lymphoma 1539: 1538: 1530: 1529: 1510: 1503: 1496: 1487: 1486: 1407: 1406: 1388: 1384: 1375: 1374: 1364: 1354: 1330: 1324: 1321: 1315: 1314: 1304: 1272: 1266: 1265: 1247: 1223: 1217: 1216: 1214: 1212: 1197: 1191: 1190: 1188: 1186: 1172: 1166: 1165: 1145: 1139: 1138: 1118: 1112: 1111: 1101: 1091: 1067: 1058: 1057: 1055: 1053: 1038: 1032: 1031: 986: 980: 979: 977: 976: 962: 949: 946: 940: 939: 913: 907: 906: 878: 872: 871: 821: 815: 814: 799:Natl Med J India 794: 788: 787: 785: 784: 756:(9): 1319–1326. 741: 735: 734: 709:(9): 1319–1326. 694: 685: 684: 677: 671: 670: 657: 651: 650: 643: 637: 636: 625: 619: 618: 605: 515:Most tumors are 454: 434: 422: 369:Salmonella typhi 295:Loss of appetite 161:Digestive system 42:Gastroenterology 31: 19: 18: 2084: 2083: 2079: 2078: 2077: 2075: 2074: 2073: 2069:Types of cancer 2049: 2048: 2047: 2042: 2010: 1943: 1901: 1811: 1786: 1768: 1666: 1643: 1632:Duodenal cancer 1624:Small intestine 1605: 1560: 1519: 1514: 1484: 1479: 1478: 1418: 1397: 1392: 1391: 1385: 1378: 1331: 1327: 1322: 1318: 1287:(11): 1577–82. 1273: 1269: 1224: 1220: 1210: 1208: 1207:. 24 March 2004 1199: 1198: 1194: 1184: 1182: 1174: 1173: 1169: 1150:J S C Med Assoc 1146: 1142: 1119: 1115: 1068: 1061: 1051: 1049: 1040: 1039: 1035: 987: 983: 974: 972: 964: 963: 952: 947: 943: 936: 914: 910: 879: 875: 822: 818: 795: 791: 782: 780: 742: 738: 695: 688: 683:. 25 June 2012. 679: 678: 674: 659: 658: 654: 645: 644: 640: 627: 626: 622: 607: 606: 599: 594: 566: 546: 517:adenocarcinomas 513: 487:cholecystectomy 483: 468: 461: 455: 446: 443:cholecystectomy 435: 426: 423: 391: 337: 267: 230:and associated 107:(most common), 17: 12: 11: 5: 2082: 2072: 2071: 2066: 2061: 2044: 2043: 2041: 2040: 2035: 2030: 2024: 2022: 2016: 2015: 2012: 2011: 2009: 2008: 2002: 2001: 1996: 1991: 1986: 1971: 1970: 1965: 1963:Adenocarcinoma 1953: 1951: 1945: 1944: 1942: 1941: 1929: 1928: 1926:Klatskin tumor 1923: 1911: 1909: 1903: 1902: 1900: 1899: 1894: 1882: 1881: 1876: 1864: 1863: 1858: 1856:Hepatoblastoma 1853: 1852: 1851: 1834: 1832: 1823: 1817: 1816: 1813: 1812: 1810: 1809: 1804: 1798: 1796: 1792: 1791: 1788: 1787: 1785: 1784: 1778: 1776: 1770: 1769: 1767: 1766: 1761: 1756: 1754:Adenocarcinoma 1747: 1746: 1741: 1736: 1727: 1722: 1713: 1712: 1676: 1674: 1668: 1667: 1665: 1664: 1659: 1653: 1651: 1645: 1644: 1642: 1641: 1640: 1639: 1637:Adenocarcinoma 1628: 1626: 1617: 1611: 1610: 1607: 1606: 1604: 1603: 1598: 1593: 1592: 1591: 1581: 1576: 1570: 1568: 1562: 1561: 1559: 1558: 1556:Adenocarcinoma 1553: 1547: 1545: 1536: 1527: 1521: 1520: 1513: 1512: 1505: 1498: 1490: 1481: 1480: 1477: 1476: 1465: 1454: 1439: 1419: 1414: 1413: 1411: 1410:Classification 1404: 1403: 1396: 1395:External links 1393: 1390: 1389: 1376: 1325: 1316: 1267: 1218: 1192: 1167: 1140: 1113: 1082:(29): 3691–3. 1059: 1033: 998:(7): 485–489. 981: 950: 941: 934: 908: 873: 816: 789: 736: 686: 672: 652: 638: 633:www.cancer.org 620: 596: 595: 593: 590: 565: 562: 545: 542: 541: 540: 537: 534: 531: 528: 512: 509: 482: 479: 467: 464: 463: 462: 459:histopathology 456: 449: 447: 441:) following a 439:adenocarcinoma 436: 429: 427: 424: 417: 411:cholelithiasis 390: 387: 386: 385: 382: 379: 376: 372: 361: 356: 354:cholelithiasis 346: 341: 336: 333: 313: 312: 302: 297: 292: 287: 281: 271: 266: 263: 226:, part of the 211: 210: 207: 203: 202: 199: 195: 194: 188: 182: 181: 168: 164: 163: 157: 151: 150: 144: 138: 137: 127: 121: 120: 117: 113: 112: 105:Adenocarcinoma 102: 98: 97: 94: 90: 89: 86: 80: 79: 60:Abdominal pain 57: 51: 50: 39: 33: 32: 24: 23: 15: 9: 6: 4: 3: 2: 2081: 2070: 2067: 2065: 2062: 2060: 2057: 2056: 2054: 2039: 2036: 2034: 2031: 2029: 2026: 2025: 2023: 2021: 2017: 2007: 2004: 2003: 2000: 1997: 1995: 1992: 1990: 1987: 1985: 1981: 1980: 1977: 1973: 1972: 1969: 1966: 1964: 1961: 1959: 1955: 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J. Cancer 1278: 1271: 1263: 1259: 1255: 1251: 1246: 1241: 1237: 1233: 1229: 1222: 1206: 1202: 1196: 1181: 1177: 1171: 1163: 1159: 1155: 1151: 1144: 1136: 1132: 1128: 1124: 1117: 1109: 1105: 1100: 1095: 1090: 1085: 1081: 1077: 1073: 1066: 1064: 1047: 1043: 1037: 1029: 1025: 1021: 1017: 1013: 1009: 1005: 1001: 997: 993: 985: 971: 967: 961: 959: 957: 955: 945: 937: 931: 927: 923: 919: 912: 904: 900: 896: 892: 888: 884: 877: 869: 865: 861: 857: 853: 849: 845: 841: 837: 836:United States 833: 829: 828: 820: 812: 808: 805:(4): 209–13. 804: 800: 793: 779: 775: 771: 767: 763: 759: 755: 751: 747: 740: 732: 728: 724: 720: 716: 712: 708: 704: 700: 693: 691: 682: 676: 668: 667: 662: 656: 648: 642: 634: 630: 624: 616: 615: 610: 604: 602: 597: 589: 587: 586:immunotherapy 583: 579: 575: 571: 561: 559: 555: 552:, bile duct, 551: 538: 535: 532: 529: 526: 525: 524: 522: 521:squamous cell 518: 508: 505: 501: 497: 492: 488: 478: 476: 472: 460: 453: 448: 444: 440: 433: 428: 421: 416: 415: 414: 412: 408: 404: 401:, endoscopic 400: 396: 383: 380: 377: 373: 370: 366: 362: 360: 357: 355: 351: 350:cholecystitis 347: 345: 342: 339: 338: 332: 330: 325: 320: 318: 310: 306: 303: 301: 298: 296: 293: 291: 288: 285: 282: 279: 275: 272: 269: 268: 262: 260: 256: 255:calcification 251: 249: 245: 241: 237: 233: 229: 225: 221: 217: 208: 204: 200: 196: 192: 189: 187: 183: 180: 176: 172: 169: 165: 162: 158: 156: 152: 149: 145: 143: 139: 136: 132: 128: 126: 122: 118: 114: 110: 106: 103: 99: 95: 91: 87: 85: 84:Complications 81: 77: 73: 69: 65: 61: 58: 56: 52: 49: 46: 43: 40: 38: 34: 30: 25: 20: 1974: 1956: 1938: 1932: 1914: 1885: 1867: 1837: 1750: 1716: 1690:hyperplastic 1679: 1672:Colon/rectum 1467: 1456: 1441: 1422: 1342: 1338: 1328: 1319: 1284: 1280: 1270: 1235: 1231: 1221: 1209:. 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Retrieved 753: 749: 739: 706: 702: 675: 664: 655: 641: 632: 623: 612: 582:radiotherapy 578:chemotherapy 567: 547: 523:carcinomas. 514: 511:Epidemiology 500:Chemotherapy 484: 469: 392: 335:Risk factors 321: 314: 252: 215: 214: 179:Chemotherapy 125:Risk factors 1934:gallbladder 1887:hyperplasia 1156:(3): 78–9. 1129:(1): 31–3. 666:Mayo Clinic 614:Mayo Clinic 507:even cure. 491:lymph nodes 375:association 300:Weight loss 274:Indigestion 232:lymph nodes 224:gallbladder 129:History of 111:(more rare) 93:Usual onset 2053:Categories 2020:Peritoneum 1469:DiseasesDB 975:2020-10-11 838:: 886–91. 783:2018-12-10 592:References 403:ultrasound 395:ultrasound 133:and other 131:Gallstones 45:Hepatology 1979:neoplasms 1916:bile duct 1839:malignant 1821:Accessory 1751:Neoplasm: 1734:Gardner's 1657:Carcinoid 1543:Esophagus 1254:0008-543X 1012:1096-9098 852:0364-2313 544:Prognosis 504:radiation 481:Treatment 389:Diagnosis 322:Of note, 278:dyspepsia 240:abdominal 198:Frequency 186:Prognosis 167:Treatment 148:Bile duct 37:Specialty 1949:Pancreas 1720:Juvenile 1694:juvenile 1649:Appendix 1525:GI tract 1387:30218788 1371:26604631 1311:18000509 1135:15974235 1108:19653352 1046:Archived 1028:43595860 1020:18802958 903:26593292 868:21799234 860:19190960 811:14606770 770:26070529 723:26070529 564:Research 558:duodenum 363:Chronic 348:Chronic 309:vomiting 305:Jaundice 290:Weakness 244:jaundice 238:such as 236:symptoms 64:Bloating 55:Symptoms 48:Oncology 1686:adenoma 1566:Stomach 1463:D005706 1362:4649107 1302:2360257 1262:8000995 1162:1063276 1099:2721248 554:stomach 399:CT scan 365:typhoid 344:Obesity 317:biliary 284:Bilious 171:Surgery 119:Unknown 1976:cystic 1869:benign 1369:  1359:  1309:  1299:  1260:  1252:  1232:Cancer 1211:8 July 1185:8 July 1160:  1133:  1106:  1096:  1026:  1018:  1010:  932:  901:  866:  858:  850:  809:  778:886615 776:  768:  731:886615 729:  721:  556:, and 248:organs 242:pain, 220:cancer 206:Deaths 116:Causes 72:Nausea 1830:Liver 1615:Lower 1534:Upper 1474:30714 1024:S2CID 864:S2CID 834:(4). 774:S2CID 727:S2CID 584:, or 550:liver 286:vomit 228:liver 101:Types 68:Fever 1774:Anus 1458:MeSH 1447:9-CM 1367:PMID 1307:PMID 1258:PMID 1250:ISSN 1213:2021 1187:2021 1158:PMID 1131:PMID 1104:PMID 1054:2012 1016:PMID 1008:ISSN 930:ISBN 899:PMID 856:PMID 848:ISSN 807:PMID 766:PMID 719:PMID 502:and 352:and 307:and 1452:156 1443:ICD 1437:C24 1433:C23 1424:ICD 1357:PMC 1347:doi 1297:PMC 1289:doi 1240:doi 1094:PMC 1084:doi 1000:doi 922:doi 891:doi 840:doi 758:doi 711:doi 407:MRI 2055:: 1982:: 1708:, 1704:, 1700:, 1696:, 1692:, 1688:, 1472:: 1461:: 1450:: 1431:: 1428:10 1379:^ 1365:. 1355:. 1343:21 1341:. 1337:. 1305:. 1295:. 1285:97 1283:. 1279:. 1256:. 1248:. 1236:75 1234:. 1230:. 1203:. 1178:. 1154:72 1152:. 1127:26 1125:. 1102:. 1092:. 1080:15 1078:. 1074:. 1062:^ 1022:. 1014:. 1006:. 996:98 994:. 968:. 953:^ 928:. 897:. 887:20 885:. 862:. 854:. 846:. 832:33 830:. 803:16 801:. 772:. 764:. 754:24 752:. 748:. 725:. 717:. 707:24 705:. 701:. 689:^ 663:. 631:. 611:. 600:^ 588:. 580:, 560:. 405:, 397:, 177:, 173:, 74:, 66:, 62:, 1960:: 1936:: 1918:: 1889:: 1871:: 1841:: 1732:/ 1683:: 1509:e 1502:t 1495:v 1445:- 1435:– 1426:- 1416:D 1373:. 1349:: 1313:. 1291:: 1264:. 1242:: 1215:. 1189:. 1164:. 1137:. 1110:. 1086:: 1056:. 1030:. 1002:: 978:. 938:. 924:: 905:. 893:: 870:. 842:: 813:. 786:. 760:: 733:. 713:: 669:. 649:. 635:. 617:. 445:. 280:) 276:(

Index


Specialty
Gastroenterology
Hepatology
Oncology
Symptoms
Abdominal pain
Bloating
Fever
Nausea
Yellowing of the skin
Complications
Adenocarcinoma
Squamous cell carcinoma
Risk factors
Gallstones
Gallbladder diseases
Diagnostic method
Bile duct
Differential diagnosis
Digestive system
Surgery
Radiation therapy
Chemotherapy
Prognosis
Five-year survival rate
cancer
gallbladder
liver
lymph nodes

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