GSK plc - Knowledge

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with standard glucose-lowering drugs." Steven Nissan and Kathy Wolkski argued that the study's low event rates reduced its statistical power. In September 2009, rosiglitazone was suspended in Europe. The results of the RECORD study were confirmed in 2013, by the Duke Clinical Research Institute, in an independent review required by the FDA. In November that year the FDA lifted the restrictions it had placed on the drug. The boxed warning about heart attack was removed; the warning about heart failure remained in place.

10959: 9607: 2236:(ASA) required GSK to withdraw its claim that Ribena Toothkind, a lower-sugar variety, did not encourage tooth decay. A company poster showed bottles of Toothkind in place of the bristles on a toothbrush. The ASA's ruling was upheld by the High Court. In 2007, GSK was fined US$ 217,000 in New Zealand over its claim that ready-to-drink Ribena contained high levels of vitamin C, after two schoolgirls showed it contained no detectable vitamin C. In 2013, GSK sold Ribena and another drink, 2028:, formerly of Smith Kline & French and the Wellcome Foundation, ""for their discoveries of important principles for drug treatment"." Elion and Hitchings were responsible for the discovery of a plethora of important drugs, including mercaptopurine and thioguanine for the treatment of leukemia, the immunosuppressant azothioprine, allopurinol for gout, pyrimethamine for malaria, the antibacterial trimethoprim, acyclovir for herpes virus infection, and nelarabine for cancer treatment. 926: 2462: 10911: 10127: 9557: 2857:

that withdrawal was indeed a problem in some patients, but there was a difference of opinion on the degree of dependence that was involved, given the possibility that the need for treatment of resistant or relapsing disease could make these drugs indispensable for patient care. The Committee expressed concern about the possibility of inappropriate prescribing resulting in the risk of problems of withdrawal outweighing the benefits of treatment with SSRIs."

2162:—charging them with violation of the Sherman Act and also seeking to have the patents declared invalid. The trial court found that the defendants had engaged in several unlawful conspiracies, but dismissed the part of the suit seeking invalidation of patents and refused to grant as relief mandatory sales of the bulk drug chemical and compulsory licensing of the patents. The government appealed to the Supreme Court, which reversed, in 798: 2443:, which obliged the company to make major changes in the way it did business, including changing its compensation programmes for its sales force and executives, and to implement and maintain transparency in its research practices and publication policies. It announced in 2013, that it would no longer pay doctors to promote its drugs or attend medical conferences, and that its sales staff would no longer have prescription targets. 2575: 330: 310: 290: 270: 247: 1309: 40: 2756: 770:(for the treatment of AIDS). In 1999, the company was the world's largest manufacturer of drugs for the treatment of asthma and HIV/AIDS. It employed 59,000 people, including 13,400 in the UK, had 76 operating companies and 50 manufacturing facilities worldwide, and seven of its products were among the world's top 50 best-selling pharmaceuticals. The company had R&D facilities in Hertfordshire, 2717:(Hycamtin). The following month prosecutors in Munich accused 70–100 doctors of having accepted bribes from SmithKline Beecham between 1997 and 1999. The inquiry was opened over allegations that the company had given over 4,000 hospital doctors money and free trips. All charges were dismissed by the Verona court in January 2009. 1947:-based technology from Sanofi and GSK's pandemic technology. The companies claimed to be able to produce one billion doses, subject to successful trials and regulatory approval, during the first half of 2021. The company also agreed to a $ 2.1 billion deal with the United States to produce 100 million doses of the vaccine. 2491:, a diabetes specialist, told medical conferences that rosiglitazone might carry an increased risk of cardiovascular problems. GSK threatened to sue him, called his university head of department, and persuaded him to sign a retraction. GSK raised questions internally about the drug's safety in 2000, and in 2002, the company 2331:

concluded that there is a clear connection between the Pandemrix vaccination campaign of 2009 and 2010, and the narcolepsy epidemic in Finland. A total of 152 cases of narcolepsy were found in Finland during 2009–2010, and ninety per cent of them had received the Pandemrix vaccination. Sweden however

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The culmination of the Consumer Healthcare string of deals will result in GSK splitting into two separate companies, via a demerger and subsequent listing of the joint venture. This will create two publicly traded companies, one focusing on pharmaceuticals and research & development, the other on

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Italian police sought bribery charges in May 2004, against 4,400 doctors and 273 GSK employees. GSK and its predecessor were accused of having spent £152m on physicians, pharmacists and others, giving them cameras, computers, holidays and cash. Doctors were alleged to have received cash based on the

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For 10 years GSK marketed Paxil as non-habit forming. In 2001, 35 patients filed a class-action suit alleging they had had withdrawal symptoms, and in 2002, a Los Angeles court issued an injunction preventing GSK from advertising that the drug was not habit forming. The court withdrew the injunction

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The results of GSK's RECORD trial were published in June 2009. It confirmed an association between rosiglitazone and an increased risk of heart failure and fractures, but not of heart attack, and concluded that it "does not increase the risk of overall cardiovascular morbidity or mortality compared

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As of 2013, RTS,S, which uses GSK's proprietary AS01 adjuvant, was being examined in a Phase 3 trial in eight African countries. PATH reported that "n the 12-month period following vaccination, RTS,S conferred approximately 50% protection from clinical Plasmodium falciparum disease in children aged

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Glaxo and Wellcome merged in 1995, to form Glaxo Wellcome plc. The merger was then considered the biggest in the UK corporate history. Glaxo Wellcome restructured its R&D operation that year, cutting 10,000 jobs worldwide, closing its R&D facility in Beckenham, Kent, and opening a Medicines

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Expert Committee on Drug Dependence, 2003: "The Committee noted the striking number of reports on paroxetine and 'withdrawal syndrome' ... The representative of Consumers International reported that a number of patients had experienced difficulty in withdrawing from SSRIs in general. It was agreed

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billion worth of products, the largest such seizure in history. In the 2010 settlement SB Pharmco pleaded guilty to criminal charges, and agreed to pay US$ 150 million in a criminal fine and forfeiture, at that time the largest such payment ever by a manufacturer of adulterated drugs, and US$

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billion worldwide sales in 2003. The company conducted nine clinical trials between 1994, and 2002, none of which showed that Paxil helped children with depression. From 1998, to 2003, it promoted the drug for the under-18s, paying physicians to go on all-expenses paid trips, five-star hotels and

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million under the False Claims Act. The fines stemmed from production of improperly made and adulterated drugs from 2001 to 2005, at GSK's subsidiary, SB Pharmco Puerto Rico Inc., in Cidra, Puerto Rico, which at the time produced US$ 5.5 billion of products each year. The drugs involved were

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their patents, subject to express licensing restrictions that the chemical from which the "finished" form of the drug (tablets and capsules) was made must not be resold in bulk form, and they licensed other drug companies to sell the drug in finished form and subject to similar restrictions. The

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GSK has largely had an access strategy, providing medicines at a subsidized price to lower and middle income markets including Africa under the former CEO Andrew Witty. In 2017, its new CEO, Emma Walmsley, shifted away from this with GSK exiting all Sub-Saharan African markets and there being no

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In October 2020, GSK told some staff that while at work they should disable the contact tracing function of the NHS test-and-trace app which monitors the spread of COVID-19. GSK explained the reason for this was due to social distancing measures in place at their sites rendering the technology

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billion in kickbacks to GSK managers, doctors, hospitals and others who prescribed their drugs, using over 700 travel agencies and consulting firms. Chinese authorities arrested four GSK executives as part of a four-month investigation into claims that doctors were bribed with cash and sexual

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SR One was established in 1985, by SmithKline Beecham to invest in new biotechnology companies and continued operating after GSK was formed; by 2003, GSK had formed another subsidiary, GSK Ventures, to out-license or start new companies around drug candidates that it did not intend to develop

2543:, not to publish it, after receiving an advance copy from one of the journal's peer reviewers, a GSK consultant. In July 2007, FDA scientists suggested that rosiglitazone had caused 83,000 excess heart attacks between 1999 and 2007. The FDA placed restrictions on the drug, including adding a 2521:

in 2005, and 2006, showed an increased risk of cardiovascular problems with rosiglitazone; the information was passed to the FDA and posted on the company website, but not otherwise published. By December 2006, rosiglitazone had become the top-selling diabetes drug, with annual sales of US$

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after the FDA objected that the court had no jurisdiction over drug marketing that the FDA had approved. In 2003, a World Health Organization committee reported that Paxil was among the top 30 drugs, and top three antidepressants, for which dependence had been reported.

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The case began in 2002, when GSK sent experts to fix problems cited by the FDA. The lead inspector recommended recalls of defective products, but they were not authorised; she was fired in 2003, and filed a whistleblower lawsuit. In 2005, federal marshals seized US$

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An internal SmithKline Beecham document said in 1998, about withheld data from two GSK studies: "It would be commercially unacceptable to include a statement that efficacy had not been demonstrated, as this would undermine the profile of paroxetine." The company

2736:. The SFO said it was collaborating with Chinese authorities to investigate bringing charges in the UK related to GSK's activities in China, Europe and the Middle East. Also as of 2014, the US Department of Justice was investigating GSK with reference to the 2483:

million for making false claims about it. The Justice Department said GSK had promoted rosiglitazone to physicians with misleading information, including that it conferred cardiovascular benefits despite an FDA-mandated label warning of cardiovascular risks.

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billion), with GSK maintaining a 68% controlling stake in the joint venture. Pfizer would own the remaining 32% shareholding. The deal builds on an earlier 2018 deal where GSK bought out Novartis' stake in the GSK-Novartis consumer healthcare joint business.

6431: 610:), and sold with the slogan "Glaxo builds bonnie babies." The Glaxo Laboratories sign is still visible on what is now a car repair shop on the main street of Bunnythorpe. The company's first pharmaceutical product, released in 1924, was vitamin D. 1999:

for his work on the chemical transmission of neural impulses. Dale served as a pharmacologist and then as Director of the Wellcome Physiological Research Laboratories from 1904 to 1914, and later served as Trustee and chairman of the board of the

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have also been reported to be interested in the business unit as they look to strengthen their presence in India. On 3 December 2018, GSK announced that Unilever would acquire the Indian-listed GlaxoSmithKline Consumer Healthcare business for US$

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then in clinical development. In 2014, this license was extended to include dolutegravir and adults with HIV. The licenses include countries in which 93 per cent of adults and 99 per cent of children with HIV live. Also in 2013 GSK joined

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wrote in 2016, that the "iconic building helped define the image of RTP," saying, "Love it or hate it, Rudolph's design remains an impressively audacious creative gesture and an important part of the history of both architecture and

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GSK manufactures products for major disease areas such as asthma, cancer, infections, diabetes, and mental health. Medicines historically discovered or developed at GSK and its legacy companies and now sold as generics include

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million. Mark Reilly, the British head of GSK's Chinese operations, received a three-year suspended prison sentence after a one-day trial held in secret. Reilly was reportedly deported from China and dismissed by the company.

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inquiry concluded in 2010, that GSK had sought to intimidate scientists who had concerns about rosiglitazone. In February that year the company tried to halt publication of an editorial about the controversy by Nissen in the

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Glaxo Wellcome and SmithKline Beecham announced their intention to merge in January 2000. The merger was completed on 27 December that year, forming GlaxoSmithKline (GSK). The company's global headquarters were at GSK House,

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Home PD, Pocock SJ, Beck-Nielsen H, et al. (June 2009). "Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial".

7869: 2119:, a British campaign to ensure that all clinical trials are registered and the results reported. The company said it would make its past clinical-trial reports available and future ones within a year of the studies' end. 6870: 6805:"Office of Public Affairs | GlaxoSmithKline to Plead Guilty & Pay $ 750 Million to Resolve Criminal and Civil Liability Regarding Manufacturing Deficiencies at Puerto Rico Plant | United States Department of Justice" 6177: 2720:

In 2006, in the United States GSK settled the largest tax dispute in IRS history, agreeing to pay US$ 3.1 billion. At issue were Zantac and other products sold in 1989–2005. The case revolved around intracompany

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Glaxo Laboratories was incorporated as a distinct subsidiary company in London in 1935. Joseph Nathan's shareholders reorganised the group's structure in 1947, making Glaxo the parent and obtained a listing on the

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5-17 months, and approximately 30% protection in children aged 6-12 weeks when administered in conjunction with Expanded Program for Immunization (EPI) vaccines." In 2014, Glaxo said it had spent more than US$ 350

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as a possible side effect to Pandemrix flu vaccination in children, and found a 6.6-fold increased risk among children and youths, resulting in 3.6 additional cases of narcolepsy per 100,000 vaccinated subjects.

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billion in deals, with Novartis selling its vaccine business to GSK and buying GSK's cancer business. In February 2015, GSK announced that it would acquire GlycoVaxyn, a Swiss pharmaceutical company, for US$

5927: 4709: 5060: 4880: 9588: 4911: 2427:, and kickbacks to physicians to prescribe GSK's drugs. There were all-expenses-paid spa treatments and hunting trips for doctors and their spouses, speakers' fees at conferences, and payment for articles 1205:. Upon completion, GSK will then own around 5.7% of Hindustan Unilever Limited, selling those shares in a number of tranches. The same day, the company also announced it would acquire oncology specialist, 4950: 2431:

by the company and placed by physicians in medical journals. The company set up a ghostwriting programme called CASPPER, initially to produce articles about Paxil but which was extended to cover Avandia.

981:, which specializes in HIV research. In 2010, the company acquired Laboratorios Phoenix, an Argentine pharmaceutical company, for US$ 253m, and the UK-based sports nutrition company Maxinutrition for £162 5026: 4678: 973:. In November 2009, the FDA approved GSK's vaccine for 2009 H1N1 influenza protection, manufactured by the company's ID Biomedical Corp in Canada. Also in November 2009, GSK formed a joint venture with 4009: 6812: 2095:

In 2009, the company said it would cut drug prices by 25 per cent in 50 of the poorest nations, release intellectual property rights for substances and processes relevant to neglected disease into a

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Subsequently, GSK declined all outside offers/attempts to acquire its consumer healthcare business and moved forward with its plan to complete the demerger from the main biopharmaceutical business.

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Rosiglitazone was associated with a significant increase in the risk of myocardial infarction and with an increase in the risk of death from cardiovascular causes that had borderline significance.

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spas. From 2004, Paxil's label, along with those of similar drugs, included an FDA-mandated boxed warning that it might increase the risk of suicidal ideation and behaviour in patients under 18.

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In April 2022, the business announced it would acquire Sierra Oncology Inc for $ 1.9 billion ($ 55 per share). In May 2022, GSK announced it would acquire Affinivax and its phase II 24-valent

6423: 4789: 2610:. The article concluded that Paxil was "generally well tolerated and effective for major depression in adolescents." The suppression of the research findings is the subject of the 2008 book 6891: 4742: 888:. The headquarters moved from the United States to England. To expand R&D in the United States, the company bought a new research center in 1995; another opened in 1997, in England at 6266: 4220: 7793: 3184: 1161:

In December 2017, Reuters reported that Glaxo had increased its stake in its Saudi Arabian unit to 75% (from 49%) taking over control from its Saudi partner Banaja KSA Holding Company.

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Among these, albendazole, amoxicillin, amoxicillin-clavulanate, allopurinol, mercaptopurine, mupirocin, pyrimethamine, ranitidine, thioguanine, trimethoprim, and zidovudine are on the

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to acquire the Consumer Healthcare business unit, with the final proposal valuing the business unit at £50 billion (£41.7 billion in cash, plus £8.3 billion in Unilever shares).

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That study was limited by low event rates, which resulted in insufficient statistical power to confirm or refute evidence of an increased risk for ischemic myocardial events.

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medication for 80 patients who are taking legal action over problems linked to the use of the swine flu vaccine, at a cost to the government of £12,000 per patient per year.

944:. In 2006, GSK acquired the US-based consumer healthcare company CNS Inc., whose products included Breathe Right nasal strips and FiberChoice dietary supplements, for US$ 566 10092: 8038: 4595: 3666: 6472: 7150: 7065: 4831: 4423: 3620: 3096: 638:(R&D) until 1987. After Glaxo bought Meyer Laboratories in 1978, it began to play an important role in the US market. In 1983, the American arm, Glaxo Inc., moved to 4496: 4400: 4078: 3742: 3070: 552:, GSK pleaded guilty to promotion of drugs for unapproved uses, failure to report safety data and kickbacks to physicians in the United States and agreed to pay a US$ 3 12781: 9637: 4701: 4291: 3844: 8176: 7519: 6673: 6576: 5200: 4972: 3995: 865:

in Belgium in 1963, to focus on vaccines. The company began to expand globally, buying seven laboratories in Canada and the United States in 1969. In 1982, it bought

12816: 9603: 8332: 6691: 5234: 3452: 5923: 1037:, northern England, designating it as the site for a previously announced biotech plant. In May that year it acquired CellZome, a German biotech company, for US$ 98 8315: 5068: 4888: 3386: 2328: 2316: 958:, was appointed chairman of the board in 2005. GSK opened its first R&D centre in China in 2007, in Shanghai, initially focused on neurodegenerative diseases. 5996: 4919: 10165: 8126: 7895: 5702: 4942: 3635: 3412: 2103:

welcomed the decision, but criticized GSK for failing to include HIV patents in its patent pool and for not including middle-income countries in the initiative.

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describing a GSK funded clinical trial that suggested rosiglitazone might have a beneficial effect on cardiovascular risk. From 2001, reports began to link the

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owned by GSK until 2013. Produced in England by H.W. Carter & Co from the 1930s, the company's unbranded syrup was distributed to children as a source of

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Four GlaxoSmithKline scientists have been recognized by the Nobel Committee for their contributions to basic medical science and/or therapeutics development.

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joined the business, which 10 years later became Smith, Kline & Co. In 1891, it merged with French, Richard and Company, and in 1929, changed its name to

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Birkett AJ, Moorthy VS, Loucq C, et al. (April 2013). "Malaria vaccine R&D in the Decade of Vaccines: breakthroughs, challenges and opportunities".

3720: 1291:, had reached an agreement to merge and combine their consumer healthcare divisions into a single entity. The combined entity would have sales of around £9.8 529: 8678: 8385: 4527: 12811: 12796: 12756: 7536: 7877: 6971: 3892: 2153:

was to keep the drug chemical out of the hands of small companies that might act as price-cutters, and the effect was to maintain stable, uniform prices.

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Since 2010, GlaxoSmithKline has several times ranked first among pharmaceutical companies on the Global Access to Medicines Index, which is funded by the

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announced that it entered into a definitive agreement with GlaxoSmithKline (GSK) for the acquisition of Sitari Pharmaceuticals by GSK. This includes its

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to encourage new drug development, and invest 20 per cent of profits from the least-developed countries in medical infrastructure for those countries.

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was in prime position to acquire GSK's interest in its Indian unit, GlaxoSmithKline Consumer Healthcare Ltd, in a sale that could generate around US$ 4

10200: 7858: 7579: 6371: 5595: 4234: 2644:, sexual dysfunction and substance addiction. GSK paid doctors to promote these off-label uses, and set up supposedly independent advisory boards and 12218: 7562:"FDA Drug Safety Communication: FDA requires removal of some prescribing and dispensing restrictions for rosiglitazone-containing diabetes medicines" 5781: 2069: 1960: 8621: 8543: 662:. The Wellcome Tropical Research Laboratories opened in 1902. In the 1920s, Burroughs Wellcome established research and manufacturing facilities in 11532: 11517: 8602: 4797: 4733: 2233: 2092:

billion treatments had been delivered, and 18 of 73 countries in which the disease is considered endemic had progressed to the surveillance stage.

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observed very few influenza cases totally in 2009 and especially 2010 as compared to most other years. In 2015, it was reported that the British

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In the 1960s, Glaxo Group Ltd. (Glaxo) and Imperial Chemical Industries (ICI) each owned patents covering various aspects of the antifungal drug

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Richards DM, Brogden RN (February 1985). "Ceftazidime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use".

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became the chief executive officer in 2008. Witty joined Glaxo in 1985, and had been president of GSK's Pharmaceuticals Europe since 2003.

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Old Ribena bottle, year unknown, made by Beecham Products, Brentford, Middlesex; the label states: "widely used in hospitals and clinics."

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Geddes AM, Klugman KP, Rolinson GN (December 2007). "Introduction: historical perspective and development of amoxicillin/clavulanate".

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Glaxo Wellcome was formed from Glaxo's 1995 acquisition of The Wellcome Foundation and SmithKline Beecham from the 1989 merger of the

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of Wellcome Research Laboratories shared the 1982 Nobel Prize for Medicine for his work on prostaglandin biology and the discovery of

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GSK acquires Cellzome 100%: Britain's largest drugmaker GlaxoSmithKline will pay about €75m in cash to acquire Cellzome AG completely

3173: 2548: 1357: 8168: 7469: 4584: 1833:. The company has committed to making the vaccine available in developing countries for five per cent above the cost of production. 12791: 7480: 7445: 4330: 4117: 2779: 2641: 8962: 8575: 8035: 6941: 2784: 1438: 862: 12505: 11501: 10024: 9487: 7867:"Readjudication of the Rosiglitazone Evaluated for Cardiovascular Outcomes and Regulation of Glycemia in Diabetes Trial (RECORD)" 7168:"Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus" 6464: 3658: 2440: 7565: 7147: 7062: 2106:

In 2013, GSK licensed its HIV portfolio to the Medicines Patent Pool for use in children, and agreed to negotiate a license for

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billion). Unilever will pay the majority of the deal in cash, with the remaining being paid in shares in its Indian operation,

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Brown AG (August 1986). "Clavulanic acid, a novel beta-lactamase inhibitor--a case study in drug discovery and development".

5435: 3612: 3542: 3370: 2729: 2333: 1802: 1112:, to 75 per cent as part of a move to focus on emerging markets. In April 2014, Novartis and Glaxo agreed on more than US$ 20 861:

as it focused more on research. Years later it bought Norden Laboratories, a business doing research into animal health, and

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The 2012 settlement included a criminal fine of US$ 242,612,800 for failing to report safety data to the FDA about Avandia (

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was hired as a researcher for Allen & Hanburys a few years after Glaxo took it over; he went on to lead the company's

12801: 11085: 9975: 9622: 9104: 8877: 5884: 5851: 4184: 2589:) for treating depression in the under-18s, although the drug had not been approved for pediatric use. Paxil had US$ 4.97 2531: 525: 8312: 5908: 5624: 3393: 12727: 11494: 11380: 9985: 9970: 8051:

Jureidini JN, McHenry LB, Mansfield PR (2008). "Clinical trials and drug promotion: Selective reporting of study 329".

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million. At the end of 2003, when generics became available in the UK, the price of paroxetine dropped by 70 per cent.

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of Glaxo Wellcome and SmithKline Beecham, which was itself a merger of a number of pharmaceutical companies around the

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Reaume A (1 January 2003). "Is Corporate Venture Capital a Prescription for Success in the Pharmaceutical Industry?".

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consumer healthcare. On 22 February 2022, GSK announced that the spin-off consumer healthcare company will be called

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million albendazole tablets every year for lymphatic filariasis until the disease is eradicated. As of 2014, over 5

1767: 802: 4550: 3712: 12806: 11899: 11486: 9955: 9525: 9434: 8670: 8375: 4519: 2304: 1930: 1109: 537: 7743:"Rosiglitazone RevisitedAn Updated Meta-analysis of Risk for Myocardial Infarction and Cardiovascular Mortality" 7544: 12019: 10762: 9922: 9855: 9480: 7327:"RECORD: Rosiglitazone Evaluated for Cardiac Outcomes and Regulation of Glycaemia in Diabetes - Full Text View" 6979: 3874: 2081: 7029: 6401: 4367: 4353: 2793: 12582: 11844: 11839: 11634: 10613: 10143: 9887: 9805: 9627: 8842: 8798: 8204: 7691:

Komajda M, McMurray JJ, Beck-Nielsen H, Gomis R, Hanefeld M, Pocock SJ, Curtis PS, Jones NP, Home PD (2010).

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billion included a criminal fine of US$ 956,814,400 and forfeiture of US$ 43,185,600. The remaining US$ 2

1918: 1707: 8096:"Efficacy of paroxetine in the treatment of adolescent major depression: a randomized, controlled trial" 7075: 2547:, but did not withdraw it. (In 2013, the FDA rejected that the drug had caused excess heart attacks.) A 2373:. The investigation was launched largely on the basis of information from four whistleblowers who filed 746:

By 1999, Glaxo Wellcome had become the world's third-largest pharmaceutical company by revenues (behind

12831: 11949: 11746: 11683: 11225: 10060: 10017: 4276: 2014:. Vane served as group research and development director for The Wellcome Foundation from 1973 to 1985. 1218: 1010: 889: 17: 12671: 12445: 12335: 11974: 11736: 11616: 11145: 9749: 9199: 8456: 6032: 6010: 3122: 2853: 2769: 2637: 2057: 1862: 1858: 1755: 1448: 407: 6142:

Koenig R (2006). "The legacy of great science: the work of Nobel Laureate Gertrude Elion lives on".

5011: 12625: 12420: 12256: 11315: 11065: 11010: 10433: 10052: 9536: 9429: 9203: 9086: 8982: 8972: 8872: 7359:"Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes" 6565:"Reverse Payments: When the Federal Trade Commission can Attack the Validity of Underlying Patents" 5924:"U.S. agrees to pay Sanofi and GSK $ 2.1 billion for 100 million doses of coronavirus vaccine" 2887: 2667:

favours. In 2014, a Chinese court found the company guilty of bribery and imposed a fine of US$ 490

2612: 2476: 2050: 1914: 1687: 1496: 1419: 813: 706: 702: 698: 635: 602:. In 1904, it began producing a dried-milk baby food from excess milk produced on dairy farms near 426: 422: 5337: 5153: 3501: 2353:

In July 2012, GSK pleaded guilty in the United States to criminal charges, and agreed to pay US$ 3

832:. By the 1960s, Beecham was extensively involved in pharmaceuticals and consumer products such as 12330: 11814: 11673: 11355: 11205: 11055: 9845: 8967: 7693:"Heart failure events with rosiglitazone in type 2 diabetes: data from the RECORD clinical trial" 7402: 6532: 4590: 3065: 2308: 1996: 1703: 1233: 1155: 740: 561: 556:

billion (£1.9bn) settlement. It was the largest health-care fraud case to date in the US and the

115: 3562: 2732:(SFO) opened a criminal inquiry in 2014 into GSK's sales practices, using powers granted by the 12701: 12470: 12400: 12370: 12325: 12271: 11929: 11869: 10871: 10777: 10722: 10423: 10097: 9820: 9689: 9253: 9042: 9012: 6750: 5852:"Alli, a popular weight-loss drug, is recalled by maker GlaxoSmithKline for possible tampering" 2774: 2423:

The settlement also covered reporting false best prices and underpaying rebates owed under the

2401: 2397: 1144: 858: 845: 711: 667: 639: 631: 73: 5824: 3437: 1956:

further. As of 2003, SR One tended to invest only if the company aligned with GSK's business.

12641: 12465: 12365: 11884: 11622: 11265: 11185: 10767: 10363: 10238: 10082: 10077: 9709: 9530: 8957: 7159: 6790: 6201: 4734:"Emma Walmsley becomes latest female CEO in FTSE 100 as she replaces Sir Andrew Witty at GSK" 3254: 2536: 2497: 2452: 2150: 2042: 1913:

As of 2013, GSK had offices in over 115 countries and employed over 99,000 people, 12,500 in

1623: 1054: 833: 825: 806: 623: 577: 487: 479: 414: 90: 4943:"Zeroing in on fast-growing vaccines, GSK sheds 2 shots to Bavarian Nordic for up to $ 1.1B" 4432:

Basilea enters into global agreement with Stiefel, a GSK company, for Toctino (alitretinoin)

4162: 4133: 2640:

and also sold as a smoking-cessation aid, Zyban – for weight loss and the treatment of

1324:

In January 2022, the company announced that they had received three unsolicited offers from

654:

Burroughs Wellcome & Company was founded in 1880, in London by the American pharmacists

56:

Head office in Brentford, London with the former GlaxoSmithKline logo, taken on 30 July 2007

12360: 12068: 12029: 12014: 11994: 11824: 11360: 11260: 11045: 10866: 10846: 10782: 10737: 10712: 10692: 10682: 10652: 10368: 10328: 9754: 8882: 8811: 7163:, attachment I, p. 143; for the ghostwritten article, attachment I, pp. 152–158. 6892:

Report from an epidemiological study in Sweden on vaccination with Pandemrix and narcolepsy

6622: 5799: 5795: 5654: 3170: 2024:, both of the Wellcome Research Laboratories, shared the 1988 Nobel Prize in Medicine with 1597: 966: 448: 359: 10488: 6838: 8: 12605: 12415: 12286: 12124: 11663: 11180: 11100: 10876: 10787: 10727: 10508: 10438: 10418: 10002: 9790: 9652: 8927: 3180:, United States Department of Justice, 2 July 2012. Katie Thomas and Michael S. Schmidt, 2599: 2492: 2428: 2111: 1537: 1361: 715: 687: 679: 627: 444: 9194: 8568: 8034:, Drug Industry Document Archive, University of California, San Francisco. Isabel Heck, 7435: 5658: 4322: 4109: 2123:

plans to provide its newer expensive oncology and genetics pipeline to this population.

12490: 12480: 11874: 11761: 11425: 11285: 11280: 11255: 10995: 10896: 10856: 10807: 10752: 10702: 10558: 10498: 10463: 10393: 10373: 10318: 10253: 8380: 8198: 8007: 7717: 7692: 7440: 7407: 7282: 7184: 7167: 6949: 6843: 6124: 5969: 5961: 5804: 5697: 5566: 4555: 4058: 3967: 3879: 3809: 3685: 3567: 3506: 3193: 3091: 2999: 2841: 2025: 1988: 1964: 1271:

to acquire Novartis's 36.5% stake in their Consumer Healthcare Joint Venture for US$ 13

1202: 817: 433: 8512: 8487: 8152:

Side Effects: A Prosecutor, a Whistleblower, and a Bestselling Antidepressant on Trial

7944: 7919: 7526:, Office of Surveillance and Epidemiology, Food and Drug Administration, 30 July 2007. 7270: 6080: 6055: 5462: 2456: 2181: 12666: 12656: 12610: 12024: 11934: 11849: 11779: 11726: 11610: 11598: 11405: 11295: 11020: 10831: 10667: 10618: 10528: 10468: 10273: 10268: 9286: 8835: 8517: 8118: 8114: 7999: 7949: 7838: 7764: 7722: 7680: 7647: 7601:"Standing firm—the European Heart Journal, scientific controversies and the industry" 7561: 7380: 7315: 7274: 7234: 7189: 6650: 6603: 6322: 6159: 6116: 6085: 5973: 5830: 5759: 5670: 5570: 5558: 5554: 5493: 5466: 5277: 4973:"GSK agrees to divest rabies and tick-borne encephalitis vaccines to Bavarian Nordic" 4488: 4246: 4025: 3959: 3884: 3814: 3783: 3538: 3366: 2912: 2693: 2657: 2502: 2300: 2192: 2017: 1018: 675: 613: 8011: 7286: 6240:"Private and Public Partners Unite to Combat 10 Neglected Tropical Diseases by 2020" 6128: 3971: 3845:"SmithKline Beckman Corp. and International Clinical Laboratories Inc. announced..." 2964: 2942: 12746: 12706: 12552: 12340: 12261: 12118: 11944: 11698: 11445: 11345: 11130: 10802: 10608: 10603: 10458: 10378: 9739: 9560: 9385: 9273: 8507: 8499: 8110: 8060: 7989: 7939: 7931: 7828: 7786:"European Medicines Agency recommends suspension of Avandia, Avandamet and Avaglim" 7759: 7754: 7742: 7712: 7704: 7670: 7637: 7612: 7370: 7305: 7266: 7224: 7179: 6155: 6151: 6108: 6075: 6067: 5953: 5751: 5662: 5550: 5458: 3949: 3130: 2761: 2733: 2722: 2510: 2370: 2303:

was developed by GlaxoSmithKline in 2006. It was used by Finland and Sweden in the

2060:(WHO), in the Global Alliance to Eliminate Lymphatic Filariasis (GAELF). Around 120 2021: 1936: 872:

Smith Kline & French merged with Beckman Inc. in 1982, and changed its name to

750:

and Merck), with a global market share of around 4 per cent. Its products included

322: 11516: 8793: 8535: 7326: 6863:"The MPA investigates reports of narcolepsy in patients vaccinated with Pandemrix" 5755: 3915:"The new alchemy – The drug industry's flurry of mergers is based on a big gamble" 2662:

In 2013, Chinese authorities announced that, since 2007, GSK had funnelled HK$ 3.8

1349:

In April 2023, GSK announced it would acquire Bellus Health Inc. for $ 2 billion.

94: 12676: 12475: 12410: 12134: 11894: 11889: 11809: 11751: 11668: 11628: 11581: 11521: 11215: 11195: 11000: 10891: 10886: 10836: 10792: 10757: 10588: 10583: 9774: 9724: 9413: 9375: 9370: 9037: 8892: 8738: 8625: 8606: 8336: 8319: 8225: 8077: 8042: 8031: 7884: 7873: 7862: 7586: 7523: 7487: 7476: 7154: 7094: 7069: 7001: 6898: 6776: 6695: 6677: 6632: 6359: 6208: 5888: 4427: 4404: 4188: 4170: 3756: 3456: 3416: 3188: 3177: 2145: 1944: 1814: 1241: 1082: 1074: 998: 978: 494: 440: 369: 8503: 8070: 7920:"Drug company experts advised staff to withhold data about SSRI use in children" 4855:"GlaxoSmithKline taps Unilever as lead bidder in Indian Horlicks buyout: report" 4431: 12536: 12500: 12276: 12160: 12108: 12084: 11979: 11939: 11904: 11570: 11450: 11370: 11330: 11245: 10968: 10963: 10958: 10593: 10568: 10523: 10453: 10398: 10112: 9734: 9657: 9606: 9449: 9395: 9360: 8815: 8788: 8282: 8193:. Associated Press. 20 August 2002. Archived from the original on 14 July 2003. 7708: 7675: 7658: 7642: 7625: 7617: 7600: 7598: 7229: 7212: 7143: 7058: 6103:

Elion GB (1993). "Acyclovir: discovery, mechanism of action, and selectivity".

5092:"Hello, Haleon: GlaxoSmithKline reveals name of £60bn consumer health spin-out" 3297: 2517:, known as RECORD, to examine rosiglitazone and cardiovascular events. Two GSK 2337: 2001: 1968: 1771: 1343:

vaccine candidate for up to $ 3.3 billion, strengthening its vaccine business.

1140: 718:, which bought the building in 2012, announced plans in 2020, to tear it down. 697:

When Burroughs Wellcome decided to move its headquarters, the company selected

683: 655: 643: 510: 483: 472: 251: 99: 10173: 7833: 7816: 7537:"FDA Adds Boxed Warning for Heart-related Risks to Anti-Diabetes Drug Avandia" 7310: 7293: 5880: 5258:"GSK: To Acquire The Late-stage Biopharmaceutical Group For $ 14.75 Per Share" 4181: 4010:"GlaxoSmithKline Completes the Purchase of Block Drug for $ 1.24 Billion" 12740: 12510: 12405: 12390: 12380: 12375: 12184: 12174: 12154: 12074: 12034: 11989: 11914: 11909: 11716: 11430: 11325: 11320: 11300: 11155: 11150: 11090: 11005: 10990: 10985: 10772: 10742: 10548: 10518: 10513: 9800: 9694: 9679: 9444: 9365: 9032: 9027: 8932: 8164: 7978:"Senate probe seeks industry payment data on individual academic researchers" 7517:"Assessment of the cardiovascular risks and health benefits of rosiglitazone" 6326: 5900: 4492: 3888: 3818: 3234:

Trademarked: A History of Well-Known Brands, from Airtex to Wright's Coal Tar

2837: 2808: 2795: 2544: 2540: 2535:

published a meta-analysis that associated the drug with an increased risk of

2518: 2506: 2472: 2465: 2389: 2226: 1787: 1723: 1484: 1375: 1151: 850: 821: 792: 732: 599: 541: 514: 410: 204: 120: 81: 12226: 8024: 5957: 5666: 5298:"GSK Puts $ 1.4B on the Line in Aiolos Acquisition to Boost Asthma Pipeline" 2256:

In 2010, the US Department of Justice announced that GSK would pay a US$ 150

1821:

is responsible for over 650,000 deaths annually, mainly in Africa. Known as

12557: 12485: 12164: 12104: 12094: 12054: 11859: 11799: 11789: 11741: 11693: 11541: 11455: 11415: 11410: 11390: 10657: 10483: 10473: 10443: 10225: 9815: 9795: 9769: 9454: 9439: 9390: 9159: 8828: 8521: 8433:"Watchdog fines GSK £37m for paying to keep generic drugs out of UK market" 8341: 8324: 8122: 8003: 7953: 7856:"FDA requires removal of certain restrictions on the diabetes drug Avandia" 7842: 7768: 7726: 7684: 7651: 7498: 7384: 7319: 7278: 7238: 7193: 7002:"Statistikdatabas för dödsorsaker (den öppna delen av dödsorsaksregistret)" 6682: 6496:"GSK stops Nairobi production as high costs and low sales eat into revenue" 6444: 6296: 6295:. World Health Organization. 18 September 2015. p. 490. Archived from 6290:"Global programme to eliminate lymphatic filariasis: progress report, 2014" 6163: 6112: 6089: 5763: 5716: 5470: 3963: 3205: 3201:"GlaxoSmithKline fined $ 3bn after bribing doctors to increase drugs sales" 3127:

World Health Organization model list of essential medicines: 21st list 2019

3030: 2417: 2225:

during World War II, which gave the drink a reputation as good for health.

2210: 2137: 2107: 2011: 1992: 1795: 1727: 1340: 1169: 1165: 1042: 959: 929: 854: 617:

Feeder bottle with valve and teat, Glaxo Laboratories, Greenford, Middlesex

594:

Joseph Nathan and Co. was founded in 1873, as a general trading company in

8330:"GSK's China crisis: chief executive Andrew Witty speaks - as it happened" 8260:"Shanghai travel agent's revenue surge led to arrests in GSK bribery case" 8064: 7896:"The FDA Responds To Steve Nissen's Criticism Of Upcoming Avandia Meeting" 7817:"Results of a reevaluation of cardiovascular outcomes in the RECORD trial" 6120: 5674: 5562: 5497: 2461: 1346:

On 16 May 2022, the company changed its name from GlaxoSmithKline to GSK.

12696: 12615: 12572: 12425: 12395: 12309: 12266: 12239: 12140: 11984: 11879: 11819: 11585: 11545: 11310: 11120: 11050: 11035: 11015: 10717: 10428: 10358: 10338: 10333: 10184: 9729: 9667: 9403: 9380: 9052: 8783: 7935: 7375: 7358: 5027:"GSK buys out Novartis in $ 13 billion consumer healthcare shake-up" 4912:"GSK slides after buying cancer firm Tesaro for hefty $ 5.1 billion" 4881:"Unilever swallows GSK's Indian Horlicks business for $ 3.8 billion" 2617: 2409: 2405: 2377:(whistleblower) lawsuits against the company under the False Claims Act. 2141: 2096: 2077: 1902: 1886: 1779: 1775: 1743: 1735: 1731: 1715: 1699: 1371:

In May 2024, GSK sold off its 4.2% shares in Haleon for $ 1.58 billion.

1070: 671: 606:. The resulting product was first known as Defiance, then as Glaxo (from 603: 582: 506: 197: 9840: 8803: 7878:"Steven Nissen: The Hidden Agenda Behind The FDA's New Avandia Hearings" 6225: 5965: 5588:"Chemical & Engineering News: Top Pharmaceuticals: 6-Mercaptopurine" 4445:"Three Lessons From GlaxoSmithKline's Purchase Of Human Genome Sciences" 3135: 2380:

The charges stemmed from GSK's promotion of the anti-depressants Paxil (

2205:

There were concerns in the 2000s about the sugar and vitamin content of

12450: 12385: 12227: 12114: 11924: 11854: 11756: 11721: 11465: 11365: 10881: 10732: 10647: 10448: 10243: 10009: 9850: 9459: 9408: 9316: 9268: 9082: 9072: 9067: 9057: 8937: 8351:"Chinese police allege Glaxo sales reps trained to offer sexual bribes" 7139: 7054: 6449: 5145:"Pfizer to exit GSK consumer health joint venture after London listing" 3914: 2697: 2586: 2578: 2381: 2361:

until then between the Justice Department and a drug company. The US$ 3

2320: 2260:

million criminal fine and forfeiture, and a civil settlement of US$ 600

2218: 2065: 1763: 1759: 1751: 1719: 1583: 1122: 1078: 951: 937: 925: 910: 829: 755: 736: 595: 545: 518: 351: 282: 227: 8640:"GlaxoSmithKline faces criminal investigation by Serious Fraud Office" 7994: 7977: 6242:. Bill & Melinda Gates Foundation. 30 January 2012. Archived from 4268:"Companies / Pharmaceuticals – GSK and Pfizer to merge HIV portfolios" 2396:. Other drugs promoted for unapproved uses were two inhalers, Advair ( 2156:

The United States brought an antitrust suit against the two companies—

1974: 12681: 12651: 12646: 12620: 12304: 12180: 11954: 11470: 11395: 11375: 11350: 11240: 11175: 11110: 10861: 10707: 10563: 10543: 10408: 10403: 10288: 10258: 10087: 9744: 9699: 9672: 9542: 9326: 9306: 9263: 9258: 9238: 9233: 9174: 9144: 9124: 9077: 9062: 9047: 8734:"GSK tells UK staff: turn off Covid test-and-trace app while at work" 7599:

Thomas F. Lüscher, Ulf Landmesser, Frank Ruschitzka (23 April 2010).

6071: 4824:"Unilever in pole position to swallow GSK's Indian Horlicks business" 3954: 3937: 2714: 2633: 2607: 2569: 2488: 2413: 2385: 2296: 2274: 2270: 2222: 2116: 2007: 1894: 1882: 1866: 1747: 1711: 1356:

for over $ 1 billion, adding to its existing asthma business through

1213:

billion. The deal will give GSK control of ovarian cancer treatment,

1189: 1066: 1034: 1006: 969:, then the world's largest independent dermatology drug company, for 906: 899: 728: 682:

worked there and invented drugs still used many years later, such as

549: 432:

GSK is the tenth largest pharmaceutical company and #294 on the 2022

10493: 7494:"Glaxo's handling of Avandia concerns damned by US Senate committee" 6315:"Drug giant GlaxoSmithKline pledges cheap medicine for world's poor" 3938:"Partners resolve their differences and unite at the second attempt" 3471:"Into the Spaceship: A Visit to the Old Burroughs Wellcome Building" 2700:

out of the UK market. The generics companies were fined a further £8

2696:

more than £50m between 2001, and 2004, to keep generic varieties of

1935:

In July 2020, the UK government signed up for 60 million doses of a

1185: 12711: 12686: 12577: 12531: 12460: 12435: 12430: 12281: 12064: 11834: 11829: 11678: 11658: 11460: 11440: 11400: 11305: 11235: 11160: 11140: 11095: 11080: 11070: 11040: 10851: 10797: 10697: 10677: 10662: 10598: 10578: 10573: 10383: 10308: 10303: 10278: 10263: 9810: 9714: 9684: 9311: 9301: 9296: 9291: 9248: 9184: 9179: 9154: 9134: 9119: 9114: 9017: 8248:, Thirty-third Report, World Health Organization, 2003, pp. 20, 25. 7490:, The United States Senate Committee on Finance, 20 February 2010. 6600:

Antitrust Law and Intellectual Property Rights: Cases and Materials

6465:"GSK cutting jobs in sub-Saharan Africa, will rely on distributors" 5061:"Drugmaker GSK to split after striking Pfizer consumer health deal" 4702:"GlaxoSmithKline Appoints Big Pharma's First Woman Chief Executive" 4520:"GSK pays $ 1 billion to lift Indian unit stake to 75 percent" 4241:. 16 November 2009. Archived from the original on 19 November 2009. 2689: 2237: 1898: 1890: 1870: 1739: 1325: 1268: 1267:

In March 2018, GSK announced that it has reached an agreement with

1229: 1177: 1130: 1098: 1090: 955: 866: 797: 763: 747: 464: 9898:

European Directorate for the Quality of Medicines & HealthCare

8619:"IRS Accepts Settlement Offer in Largest Transfer Pricing Dispute" 8376:"China Fines GlaxoSmithKline Nearly $ 500 Million in Bribery Case" 8103:

Journal of the American Academy of Child and Adolescent Psychiatry

7292:

Home PD, Pocock SJ, Beck-Nielsen H, et al. (September 2005).

6569:

Case Western Reserve Journal of Law, Technology & the Internet

5640: 5638: 3450:"Iconic Burroughs Wellcome Headquarters Open for Rare Public Tour" 2604:

Journal of the American Academy of Child and Adolescent Psychiatry

2574: 12567: 12455: 12345: 12170: 12130: 12078: 12004: 11864: 11731: 11564: 11558: 11475: 11420: 11335: 11250: 11220: 11210: 11125: 11105: 10672: 10538: 10323: 10313: 10298: 10283: 9966:

European Federation of Pharmaceutical Industries and Associations

9860: 9764: 9281: 9243: 9225: 9189: 9149: 9129: 9109: 5178:"GSK to buy Sierra Oncology amid pressure to boost drug pipeline" 5123:"GSK rejects 50-billion-pound Unilever offer for consumer assets" 4421:

GSK continues deal spree with $ 302M pact for Basilea eczema drug

2965:"GlaxoSmithKline on the Forbes Top Multinational Performers List" 2374: 2369:

billion covered a civil settlement with the government under the

2286:

600 million in civil penalties to settle the civil lawsuit.

2273:, used to treat skin infections; Paxil, the anti-depressant; and 2241: 1901:, an over-the-counter weight-loss drug, in the United States and 1878: 1818: 1791: 1256: 1255:

In July 2020, GSK acquired a 10% stake in German biotech company

1237: 1173: 1086: 1026: 1022: 1014: 759: 751: 666:, which served as the US headquarters until the company moved to 490:

of £69 billion, the eighth largest on the London Stock Exchange.

232: 8313:"GlaxoSmithKline admits some staff in China involved in bribery" 7690: 7166:

Haffner SM, Greenberg AS, Weston WM, et al. (August 2002).

7030:"DH funds private prescriptions for drug denied to NHS patients" 6372:"The Guardian: Letter in response to GSK's patent pool proposal" 1308: 39: 12515: 12144: 12088: 11919: 11794: 11784: 11604: 11275: 11190: 11170: 11135: 11115: 11030: 10533: 10503: 10348: 10293: 10233: 9865: 9825: 9759: 9612:

Pharmaceutical and biotechnology industry in the United Kingdom

9321: 9169: 9164: 9139: 8907: 8887: 7900: 7889: 7470:"Staff report on GlaxoSmithKline and the diabetes drug Avandia" 5635: 4235:"FDA Approves Additional Vaccine for 2009 H1N1 Influenza Virus" 3363:

Mega Mergers and Acquisitions: Case Studies from Key Industries

2266: 2206: 2049:-rights advocacy group gave GSK a score of 100 per cent in its 1940: 1885:

to treat cold sores; Night Nurse, a cold remedy; Breathe Right

1874: 1637: 1318: 1288: 1225: 1214: 1206: 1172:

drugs to Orchard Therapeutics in April 2018. In November 2018,

1126: 1094: 1046: 974: 917:

million and as of 2002 was home to 3,000 administrative staff.

893: 775: 767: 460: 452: 418: 364: 168: 8488:"German prosecutors probe again into bribes by drug companies" 6259:"Research-based pharma pledges on neglected tropical diseases" 6170: 3087:"GlaxoSmithKline seeks approval on first-ever malaria vaccine" 2606:, that misreported the results of one of its clinical trials, 1905:

because of possible tampering, following customer complaints.

1108:

billion to raise its stake in its Indian pharmaceutical unit,

884:

In 1989, SmithKline Beckman merged with Beecham Group to form

12495: 12350: 12251: 11688: 11435: 11385: 11290: 11075: 11025: 10747: 10553: 10478: 10413: 10248: 10093:

European and Developing Countries Clinical Trials Partnership

9719: 9662: 5312:"GSK completes acquisition of Aiolos Bio for up to $ 1.4 bln" 2214: 1822: 1062: 642:(US headquarters/research) and Zebulon (US manufacturing) in 498: 468: 456: 302: 8401:"China fines Glaxo £297m for bribery, Mark Reilly sentenced" 7479:, Committee on Finance, United States Senate, January 2010. 7255: 4585:"Deal Flurry Shows Drug Makers' Swing Toward Specialization" 909:, London, officially opened in 2002, by then-Prime Minister 853:

opened his first pharmacy in Philadelphia in 1830. In 1865,

12098: 11340: 11200: 10841: 10687: 10343: 9331: 8036:"Controversial Paxil paper still under fire 13 years later" 7291: 6353:

UNITAID Statement on GSK Patent Pool For Neglected Diseases

4409:

GSK snags proteomics platform tech in $ 98M Cellzome buyout

3459:, Triangle Modernist Houses, press release, 8 October 2012. 2539:. GSK had reportedly tried to persuade one of the authors, 2329:

The Finnish National Institute for Health and Welfare (THL)

2317:

The Finnish National Institute for Health and Welfare (THL)

2289: 2046: 1813:

In 2014, GSK applied for regulatory approval for the first

1783: 1423:(Reorganized 1929 into Smith Kline and French Laboratories) 1374:

In July 2024, GSK moved its headquarters from Brentford to

1262: 771: 10175:

Selected royal warrant holders of the British royal family

8457:"Over 4,000 doctors face charges in Italian drugs scandal" 8229:

Ronald D. White for the Los Angeles Times. 21 August 2002

7165: 5741: 5201:"GSK Bolsters Vaccines Business with $ 3.3B Affinivax Buy" 4618:"GEN - News Highlights:GSK Acquires GlycoVaxyn for $ 190M" 4551:"Novartis and Glaxo Agree to Trade $ 20 Billion in Assets" 3563:"United Therapeutics to demolish an RTP landmark building" 1061:

billion; the companies had collaborated on developing the

1029:. In 2012, the company announced that it would invest £500 876:. In 1988, it bought International Clinical Laboratories. 12600: 12150: 12009: 10353: 8671:"UK fraud office liaising with China on GSK bribery case" 8050: 3121: 2064:

million people globally are believed to be infected with

2032: 209: 7088:"GSK to stop paying doctors in major marketing overhaul" 5901:"Coronavirus vaccine: UK signs deal with GSK and Sanofi" 5432:"Most-recognized brands: Anti-infectives, December 2013" 4110:"Glaxo China R&D centre to target neurodegeneration" 4012:. PR Newswire. Archived from the original on 27 May 2014 3139:. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO. 2479:

drug approved in 1999, and a civil settlement of US$ 657

2131: 1825:, the vaccine was developed as a joint project with the 540:, primarily concerning sales and marketing of the drugs 11060: 10980: 7148:"Finance Committee Letter to the FDA Regarding Avandia" 7072:, United States Senate Finance Committee, 12 July 2010. 7063:"Finance Committee Letter to the FDA Regarding Avandia" 6533:"UNITED STATES v. GLAXO GROUP LTD., 410 U.S. 52 (1973)" 6402:"GlaxoSmithKline unit joins patent pool for AIDS drugs" 4790:"GlaxoSmithKline considers splitting up the group - FT" 4323:"UPDATE 2-Glaxo buys protein-drinks firm Maxinutrition" 2505:(the class of drugs to which rosiglitazone belongs) to 1803:

World Health Organization's List of Essential Medicines

503:

World Health Organization's List of Essential Medicines

8820: 8770: 8053:

International Journal of Risk & Safety in Medicine

7481:"Grassley, Baucus Release Committee Report on Avandia" 6912:"THL: Pandemrixilla ja narkolepsialla on selvä yhteys" 5989:"GSK to Acquire Celiac-Focused Sitari Pharmaceuticals" 1877:

brands of soft drinks, but they were sold in 2013, to

1121:

million, and in June that year that it would sell two

386: 8283:"GlaxoSmithKline executives face China bribery probe" 8257: 8169:"Drug Companies & Doctors: A Story of Corruption" 6839:"Glaxo to Pay $ 750 Million for Sale of Bad Products" 6787:

Risk Issues and Crisis Management in Public Relations

6770:"When an Icon Stumbles – The Ribena Issue Mismanaged" 5448: 4292:"GSK Acquires Laboratorios Phoenix for 3m | InfoGrok" 3532: 3182:"Glaxo Agrees to Pay $ 3 Billion in Fraud Settlement" 3060:"Glaxo Files Its Entry in Race for a Malaria Vaccine" 2632:

The company was also fined for promoting Wellbutrin (

2343: 2319:

launched investigations regarding the development of

1853:

GSK's consumer healthcare division, which earned £5.2

801:

Beecham's Clock Tower, constructed 1877, part of the

6855: 6715:"Makers of Ribena lose fight over anti-decay claims" 5645:

Elion GB (1989). "The purine path to chemotherapy".

4640:"Pfizer Buys Two GSK Meningitis Vaccines for $ 130M" 4581: 4430:; Basilea Pharmaceutica Press Release. 11 June 2012 3535:

LabOratory: Speaking of Science and Its Architecture

2751: 2713:

number of patients they treated with a cancer drug,

1287:

In December 2018, GSK announced that it, along with

10966:companies of the United Kingdom → 9903:

Medicines and Healthcare products Regulatory Agency

8191:"Judge: Paxil ads can't say it isn't habit-forming" 7917: 6222:"Global alliance to eliminate Lymphatic Filariasis" 4765:"GlaxoSmithKline boosts stake in Saudi Arabia unit" 4481:"Ribena and Lucozade sold to Japanese drinks giant" 3255:"Paths to Creating Value in Pharmaceutical Mergers" 2277:, a diabetes drug. GSK closed the factory in 2009. 1975:

Recognition, philanthropy and social responsibility

1841:

million and expected to spend an additional US$ 260

9951:Association of the British Pharmaceutical Industry 8700: 8431: 8349: 7865:, Food and Drug Administration, 25 November 2013. 7564:. Food and Drug Administration. 25 November 2013. 6781:Corporate Communications: An International Journal 5152: 4732: 4583: 4275: 4210: 3985: 3780:Beechams, 1848-2000: from Pills to Pharmaceuticals 3556: 3554: 3248: 3246: 3244: 3242: 3223:, Cambridge University Press, 1992, pp. 7–13. 3058: 1967:(TG2) small molecule program for the treatment of 1897:nicotine replacements. In March 2014, it recalled 1857:billion in 2013, sells oral healthcare, including 1085:, and in September, sold its beverage division to 936:GSK completed the acquisition of New Jersey-based 900:2000: Glaxo Wellcome and SmithKline Beecham merger 12782:Companies based in the London Borough of Hounslow 8600:"GlaxoSmithKline to Settle Tax Dispute With U.S." 8241: 8239: 7436:"A Face-Off on the Safety of a Drug for Diabetes" 7081: 5619: 5617: 5615: 5613: 5406:"GSK moves to new HQ in return to central London" 4582:Rockoff JD, Whalen J, Falconi M (22 April 2014). 4182:"Andrew Witty's journey from Graduate to GSK CEO" 3166: 2435:As part of the settlement GSK signed a five-year 2070:London Declaration on Neglected Tropical Diseases 12817:Multinational companies headquartered in England 12738: 11533:List of companies based in the Philadelphia area 10103:List of world's largest pharmaceutical companies 7465: 7463: 7251: 7249: 7206: 7204: 6053: 6033:"The Nobel Prize in Physiology or Medicine 1982" 6011:"The Nobel Prize in Physiology or Medicine 1936" 4724: 3348:, Thursday, 20 February 1947; pg. 8; Issue 50690 3164: 3162: 3160: 3158: 3156: 3154: 3152: 3150: 3148: 3146: 3052: 3050: 3048: 2680:In February 2016, the company was fined over £37 2675: 585:, with the Glaxo Laboratories sign still visible 9908:National Collaborating Centre for Mental Health 9495:GlaxoSmithKline Services Unlimited v Commission 8702:"GlaxoSmithKline faces bribery claims in Syria" 8373: 6901:, Swedish medical product agency, 30 June 2011. 6202:Profile: Buyers Guide entry for GlaxoSmithKline 5800:"Scientists See Promise in Vaccine for Malaria" 5582: 5580: 5540: 5133:on 15 January 2022 – via www.reuters.com. 5120: 5001: 4165:, GlaxoSmithKline. Retrieved 16 November 2013. 3551: 3335:, Wednesday, 8 January 1947; pg. 8; Issue 50653 3322:, Tuesday, 15 October 1935; pg. 22; Issue 47195 3252: 3239: 869:, a manufacturer of eye and skincare products. 824:. In 1859, Beecham opened its first factory in 439:, ranked behind other pharmaceutical companies 8236: 6689:"We have Frank and Vernon to thank for Ribena" 5686: 5684: 5610: 5004:"GSK buys 10% of CureVac in vaccine tech deal" 4368:"GSK confirms 500 mln stg UK investment plans" 4079:"Sir Christopher Gent to exit GlaxoSmithKline" 1681: 1381: 1158:. She is the first female CEO of the company. 836:, Lucozade and synthetic penicillin research. 735:. Also that year, Glaxo Wellcome acquired the 528:(DoJ) based on combined investigations of the 12787:Companies listed on the London Stock Exchange 12762:Biotechnology companies of the United Kingdom 12212: 11502: 10941: 10159: 10108:Pharmaceutical Services Negotiating Committee 9981:Royal Pharmaceutical Society of Great Britain 9589: 8836: 8485: 8454: 7460: 7246: 7201: 6832: 6830: 5883:, GlaxoSmithKline, accessed 16 November 2013 5874: 5388:"GSK Sells Last Haleon Shares for $ 1.58 Bln" 5264:. Archived from the original on 18 April 2023 5188:on 13 April 2022 – via www.reuters.com. 5175: 5121:Cavale S, Burger L, Dey M (15 January 2022). 4407:; John Carroll for FierceBiotech 15 May 2012 4107: 4053:. Archived from the original on 28 July 2013. 3475:Tropics of Meta historiography for the masses 3143: 3045: 2563: 1001:took over 17 GSK brands with sales of US$ 210 12822:Pharmaceutical companies established in 2000 7913: 7911: 7740: 7556: 7554: 7356: 6836: 6602:. Oxford University Press. pp. 574–75. 5921: 5693:"Gertrude Elion, Drug Developer, Dies at 81" 5577: 5363:"GSK to sell remaining 4.2% stake in Haleon" 4419:John Carroll for FiercePharma. 12 June 2012 3436:, W. W. Norton & Company, 2003, p. 2509:. In April that year, GSK began a six-year, 1845:million before seeking regulatory approval. 913:. The building was erected at a cost of £300 12812:Medical controversies in the United Kingdom 12797:Companies in the Dow Jones Global Titans 50 12757:Biotechnology companies established in 2000 8398: 8374:Bradsher K, Buckley C (19 September 2014). 7659:"The rise and fall of rosiglitazone: reply" 7076:"Inside GSK's CASSPER Ghostwriting Program" 6972:"Narkolepsia ja sikainfluenssarokote - THL" 6712: 6558: 6556: 6554: 6552: 6550: 5939: 5937: 5829:(3rd ed.). PHI Learning. p. 242. 5681: 5014:on 20 July 2020 – via uk.reuters.com. 4474: 4472: 4470: 3987:"Hall that glitters isn't shareholder gold" 2585:GSK was fined for promoting Paxil/Seroxat ( 1869:toothpastes. GSK also previously owned the 1282: 12219: 12205: 11509: 11495: 10948: 10934: 10166: 10152: 9918:Pharmaceutical Society of Northern Ireland 9596: 9582: 8843: 8829: 6827: 6649:. American Bar Association. p. 1162. 6527: 6525: 6523: 6521: 4940: 4852: 4575: 4212:"GlaxoSmithKline buys Stiefel for $ 3.6bn" 3802: 3537:. Cambridge, MA: MIT Press. pp. 4–5. 3288: 3286: 3284: 3282: 3280: 3278: 3084: 2446: 1041:million, and in June, worldwide rights to 758:(Ventolin) (for the treatment of asthma), 50: 38: 12752:2000 establishments in the United Kingdom 8511: 8246:"WHO Expert Committee on Drug Dependence" 7993: 7943: 7908: 7832: 7758: 7716: 7674: 7641: 7616: 7551: 7374: 7309: 7228: 7183: 6638: 6079: 5338:"GSK sells off remaining stake in Haleon" 5058: 4909: 4548: 4517: 4396:European Biotechnology News 16 May 2012. 4131: 3978: 3953: 3727: 3560: 3134: 3117: 3115: 3056: 2882: 2880: 2878: 2876: 2874: 2627: 2313:The Swedish Medical Products Agency (MPA) 2251: 1979: 1147:, became GSK chairman in September 2015. 820:laxative in England, giving birth to the 739:-based Affymax, a leader in the field of 478:The company has a primary listing on the 8429: 8258:Alice Yan, Toh Han Shih (16 July 2013). 7814: 6942:"Terveyden ja hyvinvoinnin laitos - THL" 6644: 6547: 6376:Médecins Sans Frontières Access Campaign 5934: 5822: 5627:. Science History Institute. June 2016. 5054: 5052: 4478: 4467: 4436: 4346:"GSK sells BC, Goody's and other brands" 4134:"Pharmaceutical futures: Made in China?" 4044: 3749: 3659:"Glaxo Wellcome plans to axe 7,500 jobs" 3468: 3462: 3434:The Architecture of Delano & Aldrich 3253:Ravenscraft DJ, Long WF (January 2000). 2780:Index of oral health and dental articles 2642:attention deficit hyperactivity disorder 2573: 2460: 2290:2010 Pandemrix connected with narcolepsy 1307: 1263:GSK–Novartis consumer healthcare buy-out 1224:In October 2019, GSK agreed to sell its 1168:, the company divested its portfolio of 932:, GSK's CEO from May 2008, to April 2017 924: 796: 694:to become more active in animal health. 612: 576: 12506:University of Pittsburgh Medical Center 10025:British National Formulary for Children 9488:Christopher v. SmithKline Beecham Corp. 8977: 8637: 8399:Moore M, Roland D (19 September 2014). 8347: 8231:U.S. Opposes Order to Pull Paxil TV Ads 7506: 7027: 6789:, Kogan Page Publishers, 2008, p. 6591: 6562: 6543:from the original on 11 September 2023. 6518: 6312: 6054:Maltzman JS, Koretzky GA (April 2003). 5999:from the original on 22 September 2019. 5089: 5024: 4817: 4815: 4730: 4208: 3935: 3656: 3633: 3610: 3379: 3275: 3236:, The History Press, 2012, p. 435. 2441:Department of Health and Human Services 1352:In February 2024, the company acquired 1033:million in manufacturing facilities in 530:Department of Health and Human Services 14: 12777:Chemical companies established in 2000 12739: 9913:Pharmaceutical Price Regulation Scheme 8731: 8668: 8217:Drug and Device Law. 14 December 2006 8163: 8090: 8025:Letter showing authorship of Study 239 7975: 7656: 7623: 7433: 7403:"Doctor Accused of Leak to Drug Maker" 7210: 6837:Harris G, Wilson D (26 October 2010). 6597: 6493: 6462: 6141: 6043:from the original on 20 February 2019. 5943: 5816: 5794: 5690: 5233:. London Stock Exchange. 16 May 2022. 5002:Schuetze A, Aripaka P (20 July 2020). 4821: 4745:from the original on 21 September 2016 4712:from the original on 10 September 2023 4598:from the original on 10 September 2023 4442: 4333:from the original on 16 December 2010. 4320: 3854:from the original on 30 September 2019 3777: 3745:from the original on 24 November 2022. 3669:from the original on 24 November 2022. 3585: 3499: 3331:J. Nathan And "Glaxo" Reorganization. 3219:R. P. T. Davenport-Hines, Judy Slinn, 3112: 3029:. stockchallenge.co.uk. Archived from 2987: 2871: 2602:an article, published in 2001, in the 2080:tablets to the WHO each year to fight 2033:Philanthropy and social responsibility 1848: 1334: 762:(for the treatment of coldsores), and 12767:British companies established in 2000 12200: 11490: 10929: 10147: 10046:Monthly Index of Medical Specialities 9577: 8963:Recherche et Industrie Thérapeutiques 8824: 8681:from the original on 21 February 2022 8581:from the original on 26 November 2017 8444:from the original on 11 January 2022. 8362:from the original on 11 January 2022. 8293:from the original on 11 February 2021 8270:from the original on 19 November 2017 8219:The FDA's Amicus Briefs on Preemption 8132:from the original on 12 February 2021 7121:from the original on 11 November 2016 7036:from the original on 25 February 2021 7008:from the original on 13 February 2021 6873:from the original on 17 February 2011 6743: 6579:from the original on 18 November 2020 6333:from the original on 5 September 2013 6232: 6102: 6056:"Azathioprine: old drug, new actions" 5986: 5849: 5705:from the original on 17 October 2009. 5644: 5625:"George Hitchings and Gertrude Elion" 5483: 5255: 5198: 5176:Grover N, Shabong Y (13 April 2022). 5049: 4784: 4782: 4668: 4343: 4239:US Food and Drug Administration (FDA) 4223:from the original on 11 January 2022. 4047:"Glaxo unit buys Breathe Right maker" 3998:from the original on 11 January 2022. 3735:"Company of the week: Glaxo Wellcome" 3613:"10,000 face Glaxo's axe at Wellcome" 3360: 3356: 3354: 3129:. Geneva: World Health Organization. 2785:Recherche et Industrie Thérapeutiques 2132:1973 Antitrust case over griseofulvin 1439:Recherche et Industrie Thérapeutiques 863:Recherche et Industrie Thérapeutiques 859:Smith Kline & French Laboratories 781: 692:Cooper, McDougall & Robertson Inc 649: 630:in 1958. The Scottish pharmacologist 10039:Journal of Pharmacy and Pharmacology 9961:European Federation of Biotechnology 8746:from the original on 3 February 2021 8650:from the original on 5 December 2020 8569:"GlaxoSmithKline Annual Report 2008" 8549:from the original on 17 October 2015 8179:from the original on 28 August 2023. 7924:Canadian Medical Association Journal 7918:W. Kondro, B. Sibbald (March 2004). 7626:"The rise and fall of rosiglitazone" 7400: 7213:"The rise and fall of rosiglitazone" 7097:, Thomson/Reuters, 17 December 2013. 6815:from the original on 19 October 2014 6475:from the original on 18 January 2018 6021:from the original on 26 August 2018. 5522:from the original on 4 December 2020 4812: 4265: 3872: 3600:from the original on 7 January 2023. 3575:from the original on 6 January 2021. 3514:from the original on 17 October 2022 3271:from the original on 7 January 2023. 3262:National Bureau of Economic Research 3073:from the original on 20 October 2020 2975:from the original on 26 January 2021 2453:Rosiglitazone § Adverse effects 2394:Federal Food, Drug, and Cosmetic Act 2068:. In 2012, the company endorsed the 1881:for £1.35bn. Other products include 1470:International Clinical Laboratories 1097:; however, the deal did not include 997:In 2011, in a US$ 660-million deal, 581:The Glaxo factory built in 1918, in 12827:Pharmaceutical companies of England 9623:Manufacturing in the United Kingdom 8952: 8947: 8942: 8878:GlaxoSmithKline Pharmaceuticals Ltd 8536:"Glaxo probed over doctor freebies" 8467:from the original on 31 August 2022 8455:Hooper J, Stewart H (27 May 2004). 6867:The Swedish Medical Products Agency 5930:from the original on 1 August 2020. 4953:from the original on 5 January 2020 4671:"Sir Philip Hampton to chair Glaxo" 4191:, GlaxoSmithKline, 12 August 2008; 4120:from the original on 11 August 2021 3767:from the original on 12 April 2023. 3723:from the original on 16 March 2023. 2927: 2532:The New England Journal of Medicine 1924: 1303: 526:United States Department of Justice 24: 12728:List of corporations in Pittsburgh 11381:Scottish Mortgage Investment Trust 9986:Worshipful Society of Apothecaries 9971:Faculty of Pharmaceutical Medicine 8388:from the original on 8 April 2023. 8311:Rupert Neate and Angela Monaghan, 7568:from the original on 24 April 2019 7543:. 14 November 2007. Archived from 7185:10.1161/01.CIR.0000025403.20953.23 6851:from the original on 5 April 2023. 6725:from the original on 24 March 2010 6412:from the original on 4 April 2023. 6378:. 24 February 2009. Archived from 5911:from the original on 29 July 2020. 5862:from the original on 28 March 2014 5812:from the original on 5 April 2023. 5723:from the original on 15 April 2018 4983:from the original on 4 August 2023 4779: 4775:from the original on 4 April 2023. 4699: 4624:. 11 February 2015. Archived from 3925:from the original on 25 July 2023. 3481:from the original on 11 April 2023 3387:"Eastchester: History of the Town" 3351: 3099:from the original on 25 April 2016 2636:) – approved at the time for 2344:2012 criminal and civil settlement 1808: 1692: 524:In 2012, under prosecution by the 421:. It was established in 2000 by a 25: 12843: 12525:Companies with split headquarters 12441:Industrial Scientific Corporation 9502:United States v. Glaxo Group Ltd. 8762: 8713:from the original on 18 June 2018 8411:from the original on 4 April 2023 8154:. Algonquin Books of Chapel Hill. 7815:McHaffey KW, et al. (2013). 7796:from the original on 29 June 2019 7741:Nissen SE, Wolski K (July 2010). 7580:Avandia. Prescribing information" 7541:U.S. Food and Drug Administration 7415:from the original on 5 April 2023 7337:from the original on 17 June 2018 6783:, 13(4), 2008, pp. 394–406. 6758:from the original on 18 June 2018 6713:Gregoriadis L (18 January 2001). 6434:from the original on 2 June 2023. 6269:from the original on 19 July 2012 5780:. GlaxoSmithKline. Archived from 5631:from the original on 9 June 2023. 5463:10.1016/j.ijantimicag.2007.07.015 5102:from the original on 5 April 2023 4887:. 3 December 2018. 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Glaxo Group Ltd. 2039:Bill and Melinda Gates Foundation 1831:Bill and Melinda Gates Foundation 1565:Burroughs Wellcome & Company 754:(for the treatment of migraine), 572: 402:(an acronym from its former name 11645:Other notable Philadelphia-based 10957: 10910: 10909: 10640:(Prior to becoming king in 2022) 10213: 10206: 10199: 10126: 10125: 9976:Pharmacists' Defence Association 9933:Veterinary Medicines Directorate 9605: 9556: 9555: 9509:United States v. GlaxoSmithKline 8725: 8693: 8662: 8631: 8612: 8593: 8561: 8528: 8479: 8448: 8423: 8392: 8367: 8305: 8251: 8211: 8183: 8157: 8144: 8115:10.1097/00004583-200107000-00010 8084: 8018: 7969: 7960: 7849: 7808: 7778: 7734: 7592: 7529: 7448:from the original on 5 June 2023 7427: 7394: 7350: 7133: 7100: 7048: 7021: 6994: 6976:Terveyden ja hyvinvoinnin laitos 6964: 6946:Terveyden ja hyvinvoinnin laitos 6934: 6922:from the original on 2 June 2020 6904: 6885: 6797: 6746:"Judge orders Ribena to fess up" 6737: 6706: 6663: 6624:United States v. Glaxo Group Ltd 6616: 6506:from the original on 9 June 2023 6487: 6456: 6438: 6416: 6394: 6364: 6345: 6306: 6282: 6214: 6194: 6135: 6096: 6047: 6025: 6003: 5980: 5915: 5893: 5843: 5788: 5770: 5735: 5709: 5598:from the original on 1 June 2023 5555:10.2165/00003495-198529020-00002 5237:from the original on 17 May 2022 5059:Hirschler B (19 December 2018). 4941:Sagonowsky E (21 October 2019). 4455:from the original on 27 May 2014 3895:from the original on 22 May 2023 3421:The Eastchester Citizen-Bulletin 2847: 2754: 2707: 2240:, to the Japanese multinational 2191: 2180: 2126: 1768:gastroesophageal reflux disorder 701:to design its new building. The 493:The company developed the first 486:. As of February 2024, it had a 329: 328: 309: 308: 289: 288: 269: 268: 246: 245: 12792:Companies in the FTSE 100 Index 12546:Subsidiary company headquarters 11900:Susquehanna International Group 9956:Chemical Industries Association 9526:Drug Industry Documents Archive 8430:Bradshaw J (12 February 2016). 7589:, Food and Drug Administration. 7363:New England Journal of Medicine 7004:(in Swedish). 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GlaxoSmithKline Inc. 8328:, 22 July 2013. Rupert Neate, 7760:10.1001/archinternmed.2010.207 6313:Boseley S (13 February 2009). 6156:10.1634/theoncologist.11-9-961 5922:Lovelace Jr B (31 July 2020). 5691:Altman LK (23 February 1999). 5090:Freeman S (22 February 2022). 4822:Gruber KW (28 November 2018). 4796:. 21 July 2018. Archived from 4646:. 22 June 2015. Archived from 4298:. 14 June 2010. Archived from 3875:"SmithKline, Beecham to Merge" 3657:Grimond M (7 September 1995). 3365:. Cham: Springer. p. 14. 3027:"FTSE All-Share Index Ranking" 3019: 2957: 2905: 2842:SmithKline Beckman Corporation 2830: 2307:of the population against the 2082:soil-transmitted helminthiasis 2056:GSK has been active, with the 1571:McDougall & Robertson Inc 1456:Specialized Instruments Corp. 598:, New Zealand, by a Londoner, 13: 1: 12772:Chemical companies of England 12583:Westinghouse Electric Company 12044:Notable Delaware Valley-based 11964:Notable Delaware Valley-based 11845:Crozer Keystone Health System 11840:Christiana Care Health System 9928:Scottish Medicines Consortium 9888:Commission on Human Medicines 9806:Cambridge Antibody Technology 9628:Economy of the United Kingdom 7747:Archives of Internal Medicine 7434:Harris G (22 February 2010). 7271:10.1016/S0140-6736(09)60953-3 7018:, diagnoskod J09, J10 och J11 6671:"Consider squash and cordial" 5987:Keown A (11 September 2019). 5946:The Journal of Private Equity 5756:10.1016/j.vaccine.2013.02.040 5151:. 1 June 2022. Archived from 4669:Quinn J (25 September 2014). 4518:Hirschler B (10 March 2014). 4321:Sandle P (13 December 2010). 4108:Ben Hirschler (24 May 2007). 4045:Stouffer R (9 October 2006). 3803:Kleinfield NR (29 May 1984). 3636:"Glaxo warns of redundancies" 3432:Peter Pennoyer, Anne Walker, 3085:Lorenzetti L (24 July 2014). 2864: 2738:Foreign Corrupt Practices Act 2676:Market manipulation in the UK 2457:Rosiglitazone § Lawsuits 2437:corporate integrity agreement 2229:bought H. W. Carter in 1955. 1908: 1730:for herpes virus infections, 1541:(Founded 1715, acquired 1958) 1427:French, Richards and Company 1312:Prior logo before 9 June 2022 1104:In March 2014, GSK paid US$ 1 839: 11231:International Airlines Group 10624:Worcestershire Medal Service 10032:British Pharmaceutical Codex 8609:, Reuters, 12 September 2006 8175:. Vol. 56, no. 1. 8173:The New York Review of Books 7357:Nissen SE, Wolski K (2007). 6494:Mwangi K (15 October 2022). 6463:Palmer E (17 January 2018). 4344:Ranii D (21 December 2011). 3805:"Smithkline: One-Drug Image" 3500:Bouton K (29 January 1989). 3469:Cummings AS (13 June 2016). 3057:Plumridge H (24 July 2014). 2935:"Headquarters | GSK US" 2646:Continuing Medical Education 2581:, known as Paxil and Seroxat 2425:Medicaid Drug Rebate Program 2392:), both in violation of the 1829:vaccines initiative and the 1366:thymic stromal lymphopoietin 1143:, at that time chair of the 992: 920: 482:and is a constituent of the 417:with global headquarters in 7: 12594:strong Pittsburgh relations 12059:Cerberus Capital Management 11950:W. L. Gore & Associates 11747:Morgan, Lewis & Bockius 11271:London Stock Exchange Group 8779:Business data for GSK plc: 8732:Davies R (6 October 2020). 8709:. Reuters. 12 August 2014. 8504:10.1136/bmj.328.7452.1333-a 8094:, et al. (July 2001). 7078:, CBS News, 21 August 2009. 6224:. Ifpma.org. Archived from 5826:Product management in India 5434:. Drugs.com. Archived from 5025:Shields M (27 March 2018). 4741:. Daily Telegraph, London. 4209:Ruddick G (20 April 2009). 3588:"The ghosts of pharma past" 2747: 2348: 1931:Sanofi–GSK COVID-19 vaccine 1919:Moon Township, Pennsylvania 1682:Research areas and products 1561:(Renamed 1924, merged 1995) 1382:Acquisition-history diagram 1217:- a member of the class of 1089:. This included the brands 879: 65:GlaxoSmithKline (2000–2022) 10: 12848: 12802:COVID-19 vaccine producers 11737:Drinker Biddle & Reath 11708:Notable Philadelphia-based 11684:Philadelphia Media Network 11226:Intermediate Capital Group 11146:F & C Investment Trust 10061:The Pharmaceutical Journal 10018:British National Formulary 8348:Philips T (26 July 2013). 8071:"Company hid suicide link" 7976:Samson K (December 2008). 7401:Saul S (30 January 2008). 7032:. Health Service Journal. 7028:Lintern S (20 July 2015). 6647:Antitrust Law Developments 6351:UNITAID 16 February 2009. 5512:"mupirocin search results" 4163:"Corporate Executive Team" 3681:"Glaxo to Acquire Affymax" 3634:Grimond M (21 June 1995). 3611:Grimond M (15 June 1995). 3586:Lesney MS (January 2004). 2888:"Preliminary Results 2023" 2655: 2567: 2564:Paroxetine (Paxil/Seroxat) 2450: 1928: 1734:for parasitic infections, 1718:for bacterial infections, 1685: 1219:poly ADP ribose polymerase 1203:Hindustan Unilever Limited 890:New Frontiers Science Park 843: 790: 786: 567: 12725: 12634: 12591: 12545: 12524: 12446:Iron City Brewing Company 12336:American Eagle Outfitters 12318: 12295: 12238: 12043: 11975:Aberdeen Asset Management 11963: 11770: 11710:professional partnerships 11707: 11644: 11617:Universal Health Services 11580: 11540: 11529: 10976: 10905: 10820:HRH The Duke of Edinburgh 10816: 10632: 10434:John Lewis & Partners 10222: 10197: 10181: 10121: 10070: 9994: 9941: 9878: 9783: 9645: 9636: 9618: 9551: 9518: 9472: 9422: 9351: 9344: 9218: 9097: 9005: 8998: 8991: 8983:Smith, Kline & French 8918: 8902: 8865: 8858: 8669:Ridley K (23 July 2014). 8638:Kollewe J (28 May 2014). 8628:, IRS, 11 September 2006. 8318:16 September 2016 at the 8224:29 September 2015 at the 8203:: CS1 maint: unfit URL ( 7834:10.1016/j.ahj.2013.05.004 7790:European Medicines Agency 7311:10.1007/s00125-005-1869-1 7243:see table 1 for timeline. 6744:Eames D (28 March 2007). 5850:Smith A (27 March 2014). 5750:(Supplement 2): B233–43. 5282:: CS1 maint: unfit URL ( 5256:Susin M (18 April 2023). 4443:Herper M (16 July 2012). 4251:: CS1 maint: unfit URL ( 4063:: CS1 maint: unfit URL ( 4030:: CS1 maint: unfit URL ( 3757:"Profile: Glaxo Wellcome" 3713:"Outlook: Glaxo Wellcome" 3123:World Health Organization 2854:World Health Organization 2770:List of toothpaste brands 2684:million in the UK by the 2638:major depressive disorder 2357:billion, in what was the 2149:effect and intent of the 2072:; it agreed to donate 400 2058:World Health Organization 1756:major depressive disorder 1449:Beckman Instruments, Inc. 1420:Smith, Kline & French 1387:GlaxoSmithKline Structure 1184:billion for the company. 886:SmithKline Beecham P.L.C. 721: 427:Smith, Kline & French 381: 350: 340: 320: 300: 280: 260: 241: 220: 185: 175: 164: 146: 129: 108: 79: 69: 61: 49: 37: 12626:Thermo Fisher Scientific 12356:Armstrong Communications 12230:corporations within the 12046:division headquarters of 11316:Pershing Square Holdings 11206:IHG Hotels & Resorts 11066:British American Tobacco 11011:Associated British Foods 10594:Veuve Clicquot Ponsardin 8973:S. E. Massengill Company 8873:GlaxoSmithKline Pakistan 8624:13 November 2020 at the 8486:Burgermeister J (2004). 8264:South China Morning Post 7709:10.1093/eurheartj/ehp604 7676:10.1093/eurheartj/ehq118 7643:10.1093/eurheartj/ehq016 7624:Nissen SE (April 2010). 7618:10.1093/eurheartj/ehq127 7230:10.1093/eurheartj/ehq016 7211:Nissen SE (April 2010). 6897:15 December 2018 at the 4266:Jack A (16 April 2009). 3873:Lohr S (13 April 1989). 3344:Joseph Nathan & Co. 3221:Glaxo: A History to 1962 3176:9 September 2014 at the 2823: 2688:for paying Generics UK, 2651: 2549:Senate Finance Committee 2101:Médecins Sans Frontières 2051:Corporate Equality Index 1794:, and the antibacterial 1688:List of GSK plc products 1497:S. E. Massengill Company 1452:(Merged 1982, Sold 1989) 1433:Smith, Kline and Company 1283:GSK–Pfizer joint venture 999:Prestige Brands Holdings 707:Georgia State University 703:Elion-Hitchings Building 636:research and development 589: 583:Bunnythorpe, New Zealand 12296:Forbes largest private 12127:(Johnson & Johnson) 11815:Brandywine Realty Trust 11773:Valley-based businesses 11674:Independence Blue Cross 11591:(rank in the 2017 list) 11551:(rank in the 2017 list) 11056:Berkeley Group Holdings 10872:James Purdey & Sons 10723:James Purdey & Sons 10424:James Purdey & Sons 9846:Reliant Pharmaceuticals 8968:Reliant Pharmaceuticals 8850: 7486:6 December 2014 at the 7475:6 December 2014 at the 7093:28 October 2014 at the 6631:4 December 2020 at the 6200:Human Rights Campaign. 5958:10.3905/jpe.2003.320058 5887:13 October 2013 at the 5667:10.1126/science.2649979 5451:Int J Antimicrob Agents 5199:Keown A (31 May 2022). 4591:The Wall Street Journal 4187:9 February 2017 at the 4169:14 October 2012 at the 3415:1 December 2020 at the 3066:The Wall Street Journal 2447:Rosiglitazone (Avandia) 2309:2009 swine flu pandemic 1997:Nobel Prize in Medicine 1708:ticarcillin-clavulanate 1704:amoxicillin-clavulanate 1645:Sitari Pharmaceuticals 1401:SmithKline Beecham Plc 1234:tick-borne encephalitis 846:SmithKline & French 741:combinatorial chemistry 562:pharmaceutical industry 473:Merck Sharp & Dohme 12807:Life sciences industry 12592:Outside companies with 12471:Mine Safety Appliances 12326:Allegheny Technologies 12298:companies headquarters 12272:PNC Financial Services 11930:Vishay Intertechnology 11870:Liberty Property Trust 11771:Other notable Delaware 10098:European Pharmacopoeia 9821:The Distillers Company 9690:Dechra Pharmaceuticals 8335:11 August 2016 at the 8047:The Brown Daily Herald 7821:American Heart Journal 7605:European Heart Journal 7217:European Heart Journal 7112:www.finance.senate.gov 6751:The New Zealand Herald 6211:. Accessed 16 May 2014 6113:10.1002/jmv.1890410503 5881:"About us: what we do" 3936:Gershon D (May 2000). 3455:28 August 2018 at the 2775:Galvani Bioelectronics 2628:Bupropion (Wellbutrin) 2582: 2554:European Heart Journal 2468: 2404:), as well as Zofran ( 2402:fluticasone propionate 2398:fluticasone/salmeterol 2252:SB Pharmco Puerto Rico 2168:, 410 U.S. 52 (1973). 1991:, a former student of 1980:Scientific recognition 1534:Joseph Nathan & Co 1313: 1145:Royal Bank of Scotland 965:In 2009, GSK acquired 933: 809: 712:Research Triangle Park 668:Research Triangle Park 640:Research Triangle Park 618: 586: 152:; 23 years ago 74:Public limited company 44:Logo since 9 June 2022 12257:Dick's Sporting Goods 12232:Pittsburgh metro area 12069:Johnson & Johnson 12020:Shire Pharmaceuticals 11266:LondonMetric Property 11186:Hikma Pharmaceuticals 10867:Holland & Holland 10847:Ede & Ravenscroft 10824:(Deceased April 2021) 10713:Holland & Holland 10693:Ede & Ravenscroft 10683:Crabtree & Evelyn 10653:Anderson and Sheppard 10369:Ede & Ravenscroft 10239:Abels Moving Services 10083:British Pharmacopoeia 10078:British Approved Name 9710:Hikma Pharmaceuticals 9531:GlaxoSmithKline Prize 8958:Human Genome Sciences 8605:29 March 2017 at the 8065:10.3233/JRS-2008-0426 7966:Goldacre 2013, p. 58. 7792:. 17 September 2018. 7585:27 March 2019 at the 7153:5 August 2010 at the 7068:5 August 2010 at the 6702:, 17 September 2013. 6694:18 April 2015 at the 6428:Medicines Patent Pool 4193:"Andrew Philip Witty" 3410:"Addition to Factory" 3318:New "Glaxo" Company. 2577: 2464: 2451:Further information: 2305:H1N1 mass vaccination 2232:In 2001, the British 2151:bulk-sale restriction 2043:Human Rights Campaign 1939:developed by GSK and 1686:Further information: 1624:Human Genome Sciences 1605:Laboratorios Phoenix 1476:Reckitt & Colman 1311: 1055:Human Genome Sciences 928: 800: 624:London Stock Exchange 616: 580: 488:market capitalisation 480:London Stock Exchange 449:Johnson & Johnson 415:biotechnology company 150:27 December 2000 27:UK healthcare company 12466:Millcraft Industries 12030:Teva Pharmaceuticals 12015:Siemens Healthineers 11995:Delaware Investments 11825:Carpenter Technology 11664:Day & Zimmermann 11261:Lloyds Banking Group 11046:Barratt Developments 10788:Turnbull & Asser 10783:Taylors of Harrogate 10509:Procter & Gamble 10419:Henry Poole & Co 10329:Charbonnel et Walker 9893:Department of Health 9791:Allen & Hanburys 9755:Silence Therapeutics 8928:Allen & Hanburys 8883:Stiefel Laboratories 8150:Alison Bass (2008). 7936:10.1503/cmaj.1040213 7502:, 22 February 2010. 7376:10.1056/NEJMoa072761 6775:4 March 2016 at the 6686:, 7 September 2010. 6645:Jacobson JM (2007). 6408:. 27 February 2013. 6228:on 27 December 2008. 6178:"Access to medicine" 5457:(Suppl 2): S109–12. 4771:. 18 December 2017. 4280:on 10 December 2022. 3646:on 26 February 2014. 3187:2 March 2017 at the 2809:51.48806°N 0.31694°W 2730:Serious Fraud Office 2334:Department of Health 2066:lymphatic filariasis 1995:, received the 1936 1598:Stiefel Laboratories 1559:Wellcome Foundation 1538:Allen & Hanburys 1378:in central London. 967:Stiefel Laboratories 954:, previously CEO of 628:Allen & Hanburys 600:Joseph Edward Nathan 360:Stiefel Laboratories 334:£12.795 billion 314:£59.005 billion 228:Pharmaceutical drugs 12606:Dreyfus Corporation 12416:Federated Investors 12371:Bruster's Ice Cream 12287:WESCO International 12125:McNeil Laboratories 11281:Marks & Spencer 11256:Legal & General 11181:Hargreaves Lansdown 11101:Croda International 10897:Truefitt & Hill 10857:Gieves & Hawkes 10808:Winsor & Newton 10703:Gieves & Hawkes 10559:Steinway & Sons 10464:Martini & Rossi 10394:Gieves & Hawkes 10374:Fortnum & Mason 9944:professional bodies 9653:AAH Pharmaceuticals 8438:The Daily Telegraph 8356:The Daily Telegraph 8167:(15 January 2009). 7982:Annals of Neurology 7522:17 May 2017 at the 6952:on 5 September 2012 6811:. 26 October 2010. 6676:10 May 2017 at the 6358:27 May 2014 at the 6302:on 17 October 2015. 6265:. 31 January 2012. 6207:13 May 2016 at the 6190:on 7 February 2014. 5823:Majumdar R (2007). 5798:(18 October 2011). 5659:1989Sci...244...41E 5438:on 27 January 2023. 5157:on 10 December 2022 5071:on 19 December 2018 4979:. 21 October 2019. 4834:on 28 November 2018 4426:29 May 2014 at the 4403:4 June 2016 at the 4350:News & Observer 4217:The Daily Telegraph 4085:. 28 October 2012. 3992:The Daily Telegraph 3921:. 20 January 2000. 3763:. 17 January 2000. 3689:. 27 January 1995. 3568:News & Observer 2805: / 2112:integrase inhibitor 1959:In September 2019, 1945:recombinant protein 1849:Consumer healthcare 1663:Bellus Health Inc. 1545:Meyer Laboratories 1462:Offner Electronics 1407:SmithKline Beckman 1362:monoclonal antibody 1335:Recent developments 1221:(PARP) inhibitors. 1005:million, including 834:Macleans toothpaste 727:Research Centre in 716:United Therapeutics 688:Wellcome Foundation 680:George H. Hitchings 674:winning scientists 404:GlaxoSmithKline plc 342:Number of employees 294:£5.308 billion 274:£6.745 billion 254:30.328 billion 34: 12642:Fisher's Big Wheel 12491:Renda Broadcasting 12481:Oxford Development 11968:foreign businesses 11966:US headquarters of 11885:Rita's Italian Ice 11875:Penn Entertainment 11762:White and Williams 11426:Standard Chartered 11406:Smith & Nephew 11286:Melrose Industries 10817:By Appointment to 10633:By Appointment to 10489:Moët & Chandon 10319:Carphone Warehouse 10226:Queen Elizabeth II 10223:By Appointment to 10182:By Appointment to 9995:Books and journals 9435:Silas M. Burroughs 8978:SmithKline Beecham 8943:Burroughs Wellcome 8381:The New York Times 8076:4 May 2015 at the 8041:5 May 2015 at the 8030:5 May 2015 at the 7883:8 May 2017 at the 7872:9 May 2017 at the 7861:4 May 2015 at the 7441:The New York Times 7408:The New York Times 7331:ClinicalTrials.gov 6869:. 18 August 2010. 6844:The New York Times 6598:Leslie CR (2011). 6563:LaHatte G (2011). 5805:The New York Times 5698:The New York Times 5318:. 16 February 2024 5211:on 5 February 2023 4922:on 3 December 2018 4891:on 3 December 2018 4556:The New York Times 3880:The New York Times 3810:The New York Times 3782:. Crucible Books. 3686:The New York Times 3507:The New York Times 3423:, 19 November 1924 3194:The New York Times 2814:51.48806; -0.31694 2583: 2503:thiazolidinediones 2469: 2384:) and Wellbutrin ( 2359:largest settlement 2327:In February 2011, 2311:. In August 2010, 2084:and to provide 600 2026:Sir James W. Black 1965:transglutaminase 2 1493:Beecham Group Ltd 1314: 1150:On 31 March 2017, 1133:for around US$ 130 934: 874:SmithKline Beckman 810: 782:SmithKline Beecham 664:Tuckahoe, New York 650:Burroughs Wellcome 619: 587: 558:largest settlement 139:SmithKline Beecham 100:FTSE 100 Component 32: 12832:Vaccine producers 12734: 12733: 12667:Fisher Scientific 12611:Eaton Corporation 12361:Augustine's Pizza 12194: 12193: 11780:Actua Corporation 11635:Burlington Stores 11611:Lincoln Financial 11599:AmerisourceBergen 11484: 11483: 11021:Auto Trader Group 10971: 10923: 10922: 10609:Wilkin & Sons 10469:McIlhenny Company 10459:Mappin & Webb 10269:Axminster Carpets 10141: 10140: 9881:regulatory bodies 9874: 9873: 9676: 9571: 9570: 9468: 9467: 9340: 9339: 9214: 9213: 8914: 8913: 8812:GSK plc companies 8542:. 12 March 2002. 7995:10.1002/ana.21271 7753:(14): 1191–1202. 7657:Slaoui M (2010). 7611:(10): 1157–1158. 7333:. 21 March 2017. 7265:(9681): 2125–35. 6263:The Pharma Letter 5836:978-81-203-3383-3 4374:. 22 March 2012. 4356:on 15 April 2012. 3850:. 13 April 1988. 3778:Corely T (2011). 3741:. 1 August 1999. 3719:. 30 March 1999. 3544:978-0-262-35636-7 3372:978-1-137-00590-8 3361:Kumar BR (2012). 2694:Norton Healthcare 2658:GSK China Scandal 2301:influenza vaccine 2269:, an antiemetic; 2140:. They created a 2018:Gertrude B. Elion 1376:New Oxford Street 1364:that targets the 1049:drug, for US$ 302 948:million in cash. 676:Gertrude B. Elion 626:. Glaxo acquired 397: 396: 374: 213: 201: 194:Jonathan Symonds 16:(Redirected from 12839: 12553:Allegheny Energy 12421:Fiesta Tableware 12341:Ampco Pittsburgh 12262:Howmet Aerospace 12221: 12214: 12207: 12198: 12197: 12119:Sherwin-Williams 11945:Wilmington Trust 11699:Urban Outfitters 11592: 11552: 11511: 11504: 11497: 11488: 11487: 11446:United Utilities 11346:Rentokil Initial 11131:Endeavour Mining 10967: 10962: 10961: 10950: 10943: 10936: 10927: 10926: 10913: 10912: 10887:Lyle & Scott 10217: 10210: 10203: 10185:King Charles III 10168: 10161: 10154: 10145: 10144: 10129: 10128: 9740:Oxford Biomedica 9670: 9643: 9642: 9610: 9609: 9598: 9591: 9584: 9575: 9574: 9559: 9558: 9386:Patrick Vallance 9349: 9348: 9078:Wellbutrin/Zyban 9003: 9002: 8996: 8995: 8863: 8862: 8845: 8838: 8831: 8822: 8821: 8774: 8773: 8771:Official website 8756: 8755: 8753: 8751: 8729: 8723: 8722: 8720: 8718: 8704: 8697: 8691: 8690: 8688: 8686: 8666: 8660: 8659: 8657: 8655: 8635: 8629: 8616: 8610: 8597: 8591: 8590: 8588: 8586: 8580: 8573: 8565: 8559: 8558: 8556: 8554: 8548: 8532: 8526: 8525: 8515: 8483: 8477: 8476: 8474: 8472: 8452: 8446: 8445: 8435: 8427: 8421: 8420: 8418: 8416: 8396: 8390: 8389: 8371: 8365: 8363: 8353: 8345:, 24 July 2013. 8309: 8303: 8302: 8300: 8298: 8289:. 11 July 2013. 8279: 8277: 8275: 8255: 8249: 8243: 8234: 8215: 8209: 8208: 8202: 8194: 8187: 8181: 8180: 8161: 8155: 8148: 8142: 8141: 8139: 8137: 8131: 8100: 8088: 8082: 8068: 8049:, 2 April 2014. 8022: 8016: 8015: 7997: 7973: 7967: 7964: 7958: 7957: 7947: 7915: 7906: 7853: 7847: 7846: 7836: 7812: 7806: 7805: 7803: 7801: 7782: 7776: 7775: 7762: 7738: 7732: 7730: 7720: 7688: 7678: 7655: 7645: 7622: 7620: 7596: 7590: 7577: 7575: 7573: 7558: 7549: 7548: 7547:on 18 June 2009. 7533: 7527: 7510: 7504: 7467: 7458: 7457: 7455: 7453: 7431: 7425: 7424: 7422: 7420: 7398: 7392: 7391: 7378: 7354: 7348: 7346: 7344: 7342: 7323: 7313: 7290: 7253: 7244: 7242: 7232: 7208: 7199: 7197: 7187: 7137: 7131: 7130: 7128: 7126: 7120: 7104: 7098: 7085: 7079: 7052: 7046: 7045: 7043: 7041: 7025: 7019: 7017: 7015: 7013: 6998: 6992: 6991: 6989: 6987: 6978:. 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Archived from 4341: 4335: 4334: 4318: 4312: 4311: 4309: 4307: 4288: 4282: 4281: 4279: 4274:. Archived from 4263: 4257: 4256: 4250: 4242: 4231: 4225: 4224: 4214: 4206: 4200: 4179: 4173: 4160: 4154: 4153: 4151: 4149: 4129: 4127: 4125: 4105: 4099: 4098: 4096: 4094: 4075: 4069: 4068: 4062: 4054: 4042: 4036: 4035: 4029: 4021: 4019: 4017: 4006: 4000: 3999: 3994:. 15 July 2002. 3989: 3982: 3976: 3975: 3957: 3955:10.1038/35012210 3933: 3927: 3926: 3911: 3905: 3904: 3902: 3900: 3870: 3864: 3863: 3861: 3859: 3841: 3835: 3834: 3832: 3830: 3800: 3794: 3793: 3775: 3769: 3768: 3753: 3747: 3746: 3731: 3725: 3724: 3709: 3703: 3702: 3700: 3698: 3677: 3671: 3670: 3654: 3648: 3647: 3642:. Archived from 3631: 3625: 3624: 3608: 3602: 3601: 3599: 3592: 3583: 3577: 3576: 3558: 3549: 3548: 3530: 3524: 3523: 3521: 3519: 3502:"The Nobel Pair" 3497: 3491: 3490: 3488: 3486: 3466: 3460: 3447: 3441: 3430: 3424: 3407: 3401: 3400: 3399:on 1 April 2016. 3398: 3392:. Archived from 3391: 3383: 3377: 3376: 3358: 3349: 3342: 3336: 3329: 3323: 3316: 3310: 3309: 3307: 3305: 3290: 3273: 3272: 3270: 3259: 3250: 3237: 3230: 3224: 3217: 3211: 3168: 3141: 3140: 3138: 3119: 3110: 3108: 3106: 3104: 3082: 3080: 3078: 3062: 3054: 3043: 3042: 3040: 3038: 3033:on 26 March 2023 3023: 3017: 3016: 3014: 3012: 2991: 2985: 2984: 2982: 2980: 2961: 2955: 2954: 2952: 2950: 2941:. Archived from 2931: 2925: 2924: 2922: 2920: 2909: 2903: 2902: 2900: 2898: 2892: 2884: 2858: 2851: 2845: 2834: 2820: 2819: 2817: 2816: 2815: 2810: 2806: 2803: 2802: 2801: 2798: 2764: 2762:Companies portal 2759: 2758: 2757: 2734:Bribery Act 2010 2723:transfer pricing 2703: 2683: 2670: 2665: 2592: 2525: 2515:randomized trial 2482: 2371:False Claims Act 2368: 2364: 2356: 2284: 2263: 2259: 2247: 2195: 2184: 2091: 2087: 2075: 2063: 2022:George Hitchings 1937:COVID-19 vaccine 1925:COVID-19 vaccine 1856: 1844: 1840: 1672: 1666: 1660: 1654: 1651:Sierra Oncology 1648: 1642: 1634: 1628: 1620: 1614: 1608: 1602: 1594: 1588: 1574: 1568: 1562: 1554: 1548: 1542: 1531: 1518: 1515:Norcliff Thayer 1510:County Chemicals 1507: 1501: 1490: 1479: 1473: 1465: 1459: 1453: 1443: 1430: 1424: 1416: 1410: 1404: 1398:GlaxoSmithKline 1304:Subsequent split 1298: 1294: 1278: 1274: 1251: 1247: 1212: 1200: 1196: 1183: 1164:With respect to 1136: 1120: 1115: 1107: 1060: 1052: 1040: 1032: 1017:, Fiber Choice, 1004: 988: 985:million (US$ 256 984: 972: 947: 943: 942:US$ 1.24 billion 916: 555: 393: 390: 388: 372: 335: 332: 331: 325: 315: 312: 311: 305: 295: 292: 291: 275: 272: 271: 263:Operating income 255: 249: 248: 207: 195: 160: 158: 153: 54: 42: 35: 31: 21: 12847: 12846: 12842: 12841: 12840: 12838: 12837: 12836: 12737: 12736: 12735: 12730: 12721: 12677:Mesta Machinery 12630: 12593: 12587: 12541: 12520: 12411:EQT Corporation 12331:American Bridge 12314: 12297: 12291: 12234: 12225: 12195: 12190: 12161:Rohm & Haas 12135:Hewlett-Packard 12048:US corporations 12047: 12045: 12039: 11967: 11965: 11959: 11890:SEI Investments 11810:Bentley Systems 11772: 11766: 11752:Pepper Hamilton 11709: 11703: 11669:FMC Corporation 11646: 11640: 11590: 11588: 11582:Delaware Valley 11576: 11550: 11548: 11536: 11525: 11522:Delaware Valley 11520:(including the 11515: 11485: 11480: 11251:Land Securities 11216:Imperial Brands 11196:Howdens Joinery 10972: 10956: 10954: 10924: 10919: 10901: 10837:Boots Opticians 10822: 10818: 10812: 10793:Vauxhall Motors 10638: 10634: 10628: 10589:Vauxhall Motors 10584:United Biscuits 10569:Tate & Lyle 10364:Elizabeth Arden 10224: 10218: 10212: 10211: 10205: 10204: 10195: 10183: 10177: 10172: 10142: 10137: 10117: 10066: 9990: 9943: 9937: 9880: 9870: 9779: 9775:ViiV Healthcare 9725:MacFarlan Smith 9632: 9614: 9604: 9602: 9572: 9567: 9547: 9514: 9464: 9418: 9414:Laurie Glimcher 9381:Manvinder Banga 9376:Roy M. Anderson 9371:Simon Dingemans 9353: 9336: 9210: 9093: 8987: 8920: 8910: 8898: 8893:ViiV Healthcare 8854: 8849: 8808: 8769: 8768: 8765: 8760: 8759: 8749: 8747: 8739:TheGuardian.com 8730: 8726: 8716: 8714: 8699: 8698: 8694: 8684: 8682: 8667: 8663: 8653: 8651: 8636: 8632: 8626:Wayback Machine 8617: 8613: 8607:Wayback Machine 8598: 8594: 8584: 8582: 8578: 8574:. p. 177. 8571: 8567: 8566: 8562: 8552: 8550: 8546: 8534: 8533: 8529: 8484: 8480: 8470: 8468: 8453: 8449: 8428: 8424: 8414: 8412: 8397: 8393: 8372: 8368: 8337:Wayback Machine 8320:Wayback Machine 8310: 8306: 8296: 8294: 8281: 8280: 8273: 8271: 8256: 8252: 8244: 8237: 8226:Wayback Machine 8216: 8212: 8196: 8195: 8189: 8188: 8184: 8162: 8158: 8149: 8145: 8135: 8133: 8129: 8098: 8089: 8085: 8078:Wayback Machine 8043:Wayback Machine 8032:Wayback Machine 8023: 8019: 7974: 7970: 7965: 7961: 7916: 7909: 7904:, 23 May 2013. 7893:, 23 May 2013. 7885:Wayback Machine 7874:Wayback Machine 7863:Wayback Machine 7854: 7850: 7813: 7809: 7799: 7797: 7784: 7783: 7779: 7739: 7735: 7597: 7593: 7587:Wayback Machine 7578: 7571: 7569: 7560: 7559: 7552: 7535: 7534: 7530: 7524:Wayback Machine 7511: 7507: 7488:Wayback Machine 7477:Wayback Machine 7468: 7461: 7451: 7449: 7432: 7428: 7418: 7416: 7399: 7395: 7369:(24): 2457–71. 7355: 7351: 7340: 7338: 7325: 7254: 7247: 7209: 7202: 7155:Wayback Machine 7138: 7134: 7124: 7122: 7118: 7106: 7105: 7101: 7095:Wayback Machine 7086: 7082: 7073: 7070:Wayback Machine 7053: 7049: 7039: 7037: 7026: 7022: 7011: 7009: 7000: 6999: 6995: 6985: 6983: 6970: 6969: 6965: 6955: 6953: 6940: 6939: 6935: 6925: 6923: 6910: 6909: 6905: 6899:Wayback Machine 6890: 6886: 6876: 6874: 6861: 6860: 6856: 6835: 6828: 6818: 6816: 6809:www.justice.gov 6803: 6802: 6798: 6777:Wayback Machine 6761: 6759: 6742: 6738: 6728: 6726: 6711: 6707: 6696:Wayback Machine 6678:Wayback Machine 6669:Oliver Thring, 6668: 6664: 6657: 6643: 6639: 6633:Wayback Machine 6621: 6617: 6610: 6596: 6592: 6582: 6580: 6561: 6548: 6531: 6530: 6519: 6509: 6507: 6492: 6488: 6478: 6476: 6461: 6457: 6443: 6439: 6422: 6421: 6417: 6400: 6399: 6395: 6385: 6383: 6382:on 20 June 2019 6370: 6369: 6365: 6360:Wayback Machine 6350: 6346: 6336: 6334: 6311: 6307: 6299: 6292: 6288: 6287: 6283: 6272: 6270: 6257: 6249: 6247: 6238: 6237: 6233: 6220: 6219: 6215: 6209:Wayback Machine 6199: 6195: 6187: 6180: 6176: 6175: 6171: 6140: 6136: 6101: 6097: 6060:J. Clin. Invest 6052: 6048: 6031: 6030: 6026: 6009: 6008: 6004: 5985: 5981: 5942: 5935: 5920: 5916: 5899: 5898: 5894: 5889:Wayback Machine 5879: 5875: 5865: 5863: 5848: 5844: 5837: 5821: 5817: 5793: 5789: 5776: 5775: 5771: 5740: 5736: 5726: 5724: 5715: 5714: 5710: 5689: 5682: 5643: 5636: 5623: 5622: 5611: 5601: 5599: 5592:pubsapp.acs.org 5586: 5585: 5578: 5539: 5535: 5525: 5523: 5510: 5509: 5505: 5482: 5478: 5447: 5443: 5430: 5429: 5425: 5415: 5413: 5410:The Independent 5404: 5403: 5399: 5386: 5385: 5381: 5371: 5369: 5361: 5360: 5356: 5346: 5344: 5336: 5335: 5331: 5321: 5319: 5310: 5309: 5305: 5296: 5295: 5291: 5275: 5274: 5267: 5265: 5254: 5250: 5240: 5238: 5229: 5228: 5224: 5214: 5212: 5197: 5193: 5174: 5170: 5160: 5158: 5149:Financial Times 5143: 5142: 5138: 5119: 5115: 5105: 5103: 5088: 5084: 5074: 5072: 5057: 5050: 5040: 5038: 5023: 5019: 5000: 4996: 4986: 4984: 4971: 4970: 4966: 4956: 4954: 4939: 4935: 4925: 4923: 4908: 4904: 4894: 4892: 4879: 4878: 4874: 4864: 4862: 4851: 4847: 4837: 4835: 4820: 4813: 4803: 4801: 4800:on 21 July 2018 4788: 4787: 4780: 4763: 4762: 4758: 4748: 4746: 4729: 4725: 4715: 4713: 4698: 4694: 4684: 4682: 4667: 4663: 4653: 4651: 4638: 4637: 4633: 4616: 4615: 4611: 4601: 4599: 4580: 4576: 4566: 4564: 4547: 4543: 4533: 4531: 4516: 4512: 4502: 4500: 4477: 4468: 4458: 4456: 4441: 4437: 4428:Wayback Machine 4418: 4414: 4405:Wayback Machine 4395: 4391: 4381: 4379: 4366: 4365: 4361: 4342: 4338: 4319: 4315: 4305: 4303: 4302:on 14 June 2010 4290: 4289: 4285: 4272:Financial Times 4264: 4260: 4244: 4243: 4233: 4232: 4228: 4207: 4203: 4189:Wayback Machine 4180: 4176: 4171:Wayback Machine 4161: 4157: 4147: 4145: 4130: 4123: 4121: 4106: 4102: 4092: 4090: 4077: 4076: 4072: 4056: 4055: 4043: 4039: 4023: 4022: 4015: 4013: 4008: 4007: 4003: 3984: 3983: 3979: 3934: 3930: 3913: 3912: 3908: 3898: 3896: 3871: 3867: 3857: 3855: 3843: 3842: 3838: 3828: 3826: 3801: 3797: 3790: 3776: 3772: 3755: 3754: 3750: 3739:The Independent 3733: 3732: 3728: 3717:The Independent 3711: 3710: 3706: 3696: 3694: 3679: 3678: 3674: 3663:The Independent 3655: 3651: 3640:The Independent 3632: 3628: 3617:The Independent 3609: 3605: 3597: 3590: 3584: 3580: 3559: 3552: 3545: 3531: 3527: 3517: 3515: 3498: 3494: 3484: 3482: 3467: 3463: 3457:Wayback Machine 3448: 3444: 3431: 3427: 3417:Wayback Machine 3408: 3404: 3396: 3389: 3385: 3384: 3380: 3373: 3359: 3352: 3343: 3339: 3330: 3326: 3317: 3313: 3303: 3301: 3292: 3291: 3276: 3268: 3257: 3251: 3240: 3231: 3227: 3218: 3214: 3209:, 3 July 2012. 3199:Simon Neville, 3197:, 2 July 2012. 3189:Wayback Machine 3178:Wayback Machine 3169: 3144: 3120: 3113: 3102: 3100: 3076: 3074: 3055: 3046: 3036: 3034: 3025: 3024: 3020: 3010: 3008: 2993: 2992: 2988: 2978: 2976: 2963: 2962: 2958: 2948: 2946: 2933: 2932: 2928: 2918: 2916: 2911: 2910: 2906: 2896: 2894: 2890: 2886: 2885: 2872: 2867: 2862: 2861: 2852: 2848: 2835: 2831: 2826: 2813: 2811: 2807: 2804: 2799: 2796: 2794: 2792: 2791: 2760: 2755: 2753: 2750: 2710: 2701: 2681: 2678: 2668: 2663: 2660: 2654: 2630: 2590: 2572: 2566: 2523: 2480: 2459: 2449: 2416:) and Valtrex ( 2400:) and Flovent ( 2366: 2362: 2354: 2351: 2346: 2336:was paying for 2292: 2282: 2261: 2257: 2254: 2245: 2203: 2202: 2201: 2200: 2199: 2196: 2187: 2186: 2185: 2174: 2146:cross-licensing 2134: 2129: 2089: 2085: 2073: 2061: 2041:. In 2014, the 2035: 1982: 1977: 1961:Avalon Ventures 1953: 1933: 1927: 1911: 1854: 1851: 1842: 1838: 1815:malaria vaccine 1811: 1809:Malaria vaccine 1695: 1693:Pharmaceuticals 1690: 1684: 1679: 1678: 1677: 1671:(Acquired 2024) 1670: 1665:(Acquired 2023) 1664: 1659:(Acquired 2022) 1658: 1653:(Acquired 2022) 1652: 1647:(Acquired 2019) 1646: 1641:(Acquired 2019) 1640: 1633:(Acquired 2015) 1632: 1627:(Acquired 2013) 1626: 1619:(Acquired 2011) 1618: 1613:(Acquired 2010) 1612: 1607:(Acquired 2010) 1606: 1601:(Acquired 2009) 1600: 1593:(Acquired 2006) 1592: 1587:(Acquired 2001) 1586: 1573:(Acquired 1959) 1572: 1566: 1560: 1553:(Acquired 1995) 1552: 1546: 1540: 1529: 1525:Glaxo Wellcome 1517:(Acquired 1986) 1516: 1506:(Acquired 1953) 1505: 1500:(Acquired 1971) 1499: 1488: 1478:(Acquired 1999) 1477: 1472:(Acquired 1989) 1471: 1464:(Acquired 1961) 1463: 1458:(Acquired 1954) 1457: 1451: 1442:(Acquired 1968) 1441: 1429:(Acquired 1891) 1428: 1422: 1414: 1413:SmithKline-RIT 1408: 1402: 1388: 1384: 1337: 1306: 1296: 1295:billion ($ 12.7 1292: 1285: 1276: 1272: 1265: 1249: 1245: 1242:Bavarian Nordic 1210: 1198: 1194: 1181: 1134: 1129:, Nimenrix and 1118: 1113: 1105: 1083:atherosclerosis 1075:type 2 diabetes 1058: 1057:(HGS) for US$ 3 1050: 1038: 1030: 1002: 995: 986: 982: 979:ViiV Healthcare 971:US$ 3.6 billion 970: 945: 941: 923: 914: 902: 882: 848: 842: 818:Beecham's Pills 795: 789: 784: 724: 686:. In 1959, the 660:Silas Burroughs 652: 592: 575: 570: 553: 495:malaria vaccine 441:China Resources 406:) is a British 385: 377: 370:ViiV Healthcare 343: 333: 321: 313: 301: 293: 285: 273: 265: 250: 237: 216: 188: 178: 156: 154: 151: 142: 125: 104: 84: 57: 45: 28: 23: 22: 15: 12: 11: 5: 12845: 12835: 12834: 12829: 12824: 12819: 12814: 12809: 12804: 12799: 12794: 12789: 12784: 12779: 12774: 12769: 12764: 12759: 12754: 12749: 12732: 12731: 12726: 12723: 12722: 12720: 12719: 12714: 12709: 12704: 12699: 12694: 12689: 12684: 12679: 12674: 12669: 12664: 12659: 12654: 12649: 12644: 12638: 12636: 12632: 12631: 12629: 12628: 12623: 12618: 12613: 12608: 12603: 12597: 12595: 12589: 12588: 12586: 12585: 12580: 12575: 12570: 12565: 12560: 12555: 12549: 12547: 12543: 12542: 12540: 12539: 12537:Nova Chemicals 12534: 12528: 12526: 12522: 12521: 12519: 12518: 12513: 12508: 12503: 12501:Sarris Candies 12498: 12493: 12488: 12483: 12478: 12473: 12468: 12463: 12458: 12453: 12448: 12443: 12438: 12433: 12428: 12423: 12418: 12413: 12408: 12403: 12401:Duquesne Light 12398: 12393: 12388: 12383: 12378: 12373: 12368: 12363: 12358: 12353: 12348: 12343: 12338: 12333: 12328: 12322: 12320: 12316: 12315: 12313: 12312: 12307: 12301: 12299: 12293: 12292: 12290: 12289: 12284: 12279: 12277:PPG Industries 12274: 12269: 12264: 12259: 12254: 12248: 12246: 12236: 12235: 12224: 12223: 12216: 12209: 12201: 12192: 12191: 12189: 12188: 12178: 12168: 12158: 12148: 12138: 12128: 12122: 12112: 12102: 12092: 12085:Delmarva Power 12082: 12072: 12062: 12051: 12049: 12041: 12040: 12038: 12037: 12032: 12027: 12022: 12017: 12012: 12007: 12005:Keystone Foods 12002: 11997: 11992: 11987: 11982: 11980:AgustaWestland 11977: 11971: 11969: 11961: 11960: 11958: 11957: 11952: 11947: 11942: 11937: 11932: 11927: 11922: 11917: 11912: 11907: 11902: 11897: 11892: 11887: 11882: 11877: 11872: 11867: 11862: 11857: 11852: 11850:David's Bridal 11847: 11842: 11837: 11832: 11827: 11822: 11817: 11812: 11807: 11802: 11797: 11792: 11787: 11782: 11776: 11774: 11768: 11767: 11765: 11764: 11759: 11754: 11749: 11744: 11739: 11734: 11729: 11727:Cozen O'Connor 11724: 11719: 11713: 11711: 11705: 11704: 11702: 11701: 11696: 11691: 11686: 11681: 11676: 11671: 11666: 11661: 11656: 11650: 11648: 11642: 11641: 11639: 11638: 11632: 11626: 11620: 11614: 11608: 11602: 11595: 11593: 11578: 11577: 11575: 11574: 11571:Crown Holdings 11568: 11562: 11555: 11553: 11538: 11537: 11530: 11527: 11526: 11514: 11513: 11506: 11499: 11491: 11482: 11481: 11479: 11478: 11473: 11468: 11463: 11458: 11453: 11448: 11443: 11438: 11433: 11428: 11423: 11418: 11413: 11408: 11403: 11398: 11393: 11388: 11383: 11378: 11373: 11368: 11363: 11358: 11353: 11348: 11343: 11338: 11333: 11328: 11323: 11318: 11313: 11308: 11303: 11298: 11293: 11288: 11283: 11278: 11273: 11268: 11263: 11258: 11253: 11248: 11243: 11238: 11233: 11228: 11223: 11218: 11213: 11208: 11203: 11198: 11193: 11188: 11183: 11178: 11173: 11168: 11163: 11158: 11153: 11148: 11143: 11138: 11133: 11128: 11123: 11118: 11113: 11108: 11103: 11098: 11093: 11088: 11083: 11078: 11073: 11068: 11063: 11058: 11053: 11048: 11043: 11038: 11033: 11028: 11023: 11018: 11013: 11008: 11003: 10998: 10996:Anglo American 10993: 10988: 10983: 10977: 10974: 10973: 10953: 10952: 10945: 10938: 10930: 10921: 10920: 10918: 10917: 10906: 10903: 10902: 10900: 10899: 10894: 10889: 10884: 10879: 10874: 10869: 10864: 10859: 10854: 10852:Frank Smythson 10849: 10844: 10839: 10834: 10828: 10826: 10814: 10813: 10811: 10810: 10805: 10800: 10795: 10790: 10785: 10780: 10778:Shepherd Neame 10775: 10770: 10765: 10760: 10755: 10750: 10745: 10740: 10735: 10730: 10725: 10720: 10715: 10710: 10705: 10700: 10698:Frank Smythson 10695: 10690: 10685: 10680: 10675: 10673:Bentley Motors 10670: 10665: 10660: 10655: 10650: 10644: 10642: 10636:Prince Charles 10630: 10629: 10627: 10626: 10621: 10616: 10611: 10606: 10601: 10596: 10591: 10586: 10581: 10576: 10571: 10566: 10561: 10556: 10551: 10546: 10541: 10536: 10531: 10526: 10521: 10516: 10511: 10506: 10501: 10496: 10491: 10486: 10481: 10476: 10471: 10466: 10461: 10456: 10454:Louis Roederer 10451: 10446: 10441: 10436: 10431: 10426: 10421: 10416: 10411: 10406: 10401: 10399:Hardy Brothers 10396: 10391: 10386: 10384:Frank Smythson 10381: 10376: 10371: 10366: 10361: 10356: 10351: 10346: 10341: 10336: 10331: 10326: 10321: 10316: 10311: 10306: 10301: 10296: 10291: 10286: 10284:Bentley Motors 10281: 10276: 10271: 10266: 10261: 10256: 10251: 10246: 10241: 10236: 10230: 10228: 10220: 10219: 10198: 10196: 10194: 10193: 10189: 10187: 10179: 10178: 10171: 10170: 10163: 10156: 10148: 10139: 10138: 10136: 10135: 10122: 10119: 10118: 10116: 10115: 10113:Wellcome Trust 10110: 10105: 10100: 10095: 10090: 10085: 10080: 10074: 10072: 10068: 10067: 10065: 10064: 10057: 10049: 10042: 10035: 10028: 10021: 10014: 10006: 9998: 9996: 9992: 9991: 9989: 9988: 9983: 9978: 9973: 9968: 9963: 9958: 9953: 9947: 9945: 9939: 9938: 9936: 9935: 9930: 9925: 9920: 9915: 9910: 9905: 9900: 9895: 9890: 9884: 9882: 9879:Government and 9876: 9875: 9872: 9871: 9869: 9868: 9863: 9858: 9853: 9848: 9843: 9838: 9833: 9831:Glaxo Wellcome 9828: 9823: 9818: 9813: 9808: 9803: 9798: 9793: 9787: 9785: 9781: 9780: 9778: 9777: 9772: 9767: 9762: 9757: 9752: 9747: 9742: 9737: 9735:Norbrook Group 9732: 9727: 9722: 9717: 9712: 9707: 9702: 9697: 9692: 9687: 9682: 9677: 9665: 9660: 9658:Alliance Boots 9655: 9649: 9647: 9640: 9634: 9633: 9631: 9630: 9625: 9619: 9616: 9615: 9601: 9600: 9593: 9586: 9578: 9569: 9568: 9566: 9565: 9552: 9549: 9548: 9546: 9545: 9540: 9533: 9528: 9522: 9520: 9516: 9515: 9513: 9512: 9505: 9498: 9491: 9484: 9476: 9474: 9470: 9469: 9466: 9465: 9463: 9462: 9457: 9452: 9450:Henry Wellcome 9447: 9442: 9437: 9432: 9430:Thomas Beecham 9426: 9424: 9420: 9419: 9417: 9416: 9411: 9406: 9401: 9398: 9396:Lynn Elsenhans 9393: 9388: 9383: 9378: 9373: 9368: 9363: 9361:Philip Hampton 9357: 9355: 9346: 9342: 9341: 9338: 9337: 9335: 9334: 9329: 9324: 9319: 9314: 9309: 9304: 9299: 9294: 9289: 9287:Goody's Powder 9284: 9279: 9276: 9271: 9266: 9261: 9256: 9251: 9246: 9241: 9236: 9231: 9228: 9222: 9220: 9216: 9215: 9212: 9211: 9209: 9208: 9197: 9192: 9187: 9182: 9177: 9172: 9167: 9162: 9157: 9152: 9147: 9142: 9137: 9132: 9127: 9122: 9117: 9112: 9107: 9101: 9099: 9095: 9094: 9092: 9091: 9080: 9075: 9070: 9065: 9060: 9055: 9050: 9045: 9040: 9035: 9030: 9025: 9020: 9015: 9009: 9007: 9000: 8993: 8989: 8988: 8986: 8985: 8980: 8975: 8970: 8965: 8960: 8955: 8953:Glaxo Wellcome 8950: 8945: 8940: 8935: 8930: 8924: 8922: 8916: 8915: 8912: 8911: 8906: 8904: 8900: 8899: 8897: 8896: 8890: 8885: 8880: 8875: 8869: 8867: 8860: 8856: 8855: 8848: 8847: 8840: 8833: 8825: 8819: 8818: 8816:OpenCorporates 8809: 8807: 8806: 8801: 8796: 8791: 8786: 8780: 8777: 8775: 8764: 8763:External links 8761: 8758: 8757: 8724: 8692: 8661: 8630: 8611: 8592: 8560: 8527: 8498:(7452): 1333. 8478: 8447: 8422: 8391: 8366: 8304: 8250: 8235: 8210: 8182: 8156: 8143: 8109:(7): 762–772. 8083: 8059:(1–2): 73–81. 8017: 7968: 7959: 7907: 7848: 7827:(2): 240–249. 7807: 7777: 7733: 7669:(10): 1282–4. 7591: 7550: 7528: 7505: 7492:Andrew Clark, 7459: 7426: 7393: 7349: 7304:(9): 1726–35. 7245: 7223:(7): 773–776. 7200: 7144:Chuck Grassley 7132: 7099: 7080: 7059:Chuck Grassley 7047: 7020: 6993: 6982:on 17 May 2013 6963: 6933: 6903: 6884: 6854: 6826: 6796: 6736: 6705: 6662: 6655: 6637: 6615: 6608: 6590: 6546: 6517: 6486: 6455: 6437: 6415: 6393: 6363: 6344: 6305: 6281: 6231: 6213: 6193: 6169: 6134: 6095: 6046: 6037:NobelPrize.org 6024: 6015:NobelPrize.org 6002: 5979: 5933: 5914: 5892: 5873: 5842: 5835: 5815: 5787: 5769: 5734: 5708: 5680: 5653:(4900): 41–7. 5634: 5609: 5576: 5533: 5503: 5486:Drug Des Deliv 5476: 5441: 5423: 5412:. 13 July 2024 5397: 5379: 5354: 5329: 5303: 5289: 5248: 5222: 5191: 5168: 5136: 5113: 5082: 5048: 5017: 4994: 4964: 4933: 4902: 4872: 4845: 4811: 4778: 4756: 4723: 4692: 4661: 4631: 4609: 4574: 4541: 4510: 4466: 4435: 4412: 4389: 4359: 4336: 4313: 4283: 4258: 4226: 4201: 4174: 4155: 4100: 4070: 4037: 4001: 3977: 3928: 3906: 3865: 3836: 3795: 3789:978-1905472147 3788: 3770: 3748: 3726: 3704: 3672: 3649: 3626: 3603: 3578: 3550: 3543: 3525: 3492: 3461: 3442: 3425: 3402: 3378: 3371: 3350: 3337: 3324: 3311: 3300:on 8 June 2011 3274: 3238: 3232:David Newton, 3225: 3212: 3142: 3111: 3044: 3018: 2986: 2956: 2945:on 22 May 2022 2926: 2904: 2869: 2868: 2866: 2863: 2860: 2859: 2846: 2828: 2827: 2825: 2822: 2789: 2788: 2782: 2777: 2772: 2766: 2765: 2749: 2746: 2709: 2706: 2677: 2674: 2656:Main article: 2653: 2650: 2629: 2626: 2568:Main article: 2565: 2562: 2529:In June 2007, 2495:an article in 2448: 2445: 2350: 2347: 2345: 2342: 2338:Sodium oxybate 2291: 2288: 2253: 2250: 2197: 2190: 2189: 2188: 2179: 2178: 2177: 2176: 2175: 2173: 2170: 2133: 2130: 2128: 2125: 2034: 2031: 2030: 2029: 2015: 2005: 2002:Wellcome Trust 1981: 1978: 1976: 1973: 1969:celiac disease 1952: 1949: 1929:Main article: 1926: 1923: 1910: 1907: 1850: 1847: 1810: 1807: 1772:mercaptopurine 1746:for epilepsy, 1694: 1691: 1683: 1680: 1676: 1675: 1674: 1673: 1667: 1661: 1655: 1649: 1643: 1635: 1629: 1621: 1615: 1611:Maxinutrition 1609: 1603: 1595: 1589: 1581: 1580: 1579: 1578: 1577: 1576: 1575: 1569: 1567:(Founded 1880) 1557: 1556: 1555: 1549: 1543: 1535: 1523: 1522: 1521: 1520: 1519: 1513: 1512: 1511: 1508: 1502: 1482: 1481: 1480: 1474: 1468: 1467: 1466: 1460: 1446: 1445: 1444: 1436: 1435: 1434: 1431: 1415:(Renamed 1968) 1409:(Renamed 1982) 1403:(Renamed 1989) 1390: 1389: 1386: 1385: 1383: 1380: 1360:a long-acting 1336: 1333: 1305: 1302: 1284: 1281: 1264: 1261: 1197:billion (£2.98 1176:reported that 1141:Philip Hampton 1045:(Toctino), an 1019:Goody's Powder 994: 991: 922: 919: 901: 898: 881: 878: 844:Main article: 841: 838: 814:Thomas Beecham 791:Main article: 788: 785: 783: 780: 723: 720: 684:mercaptopurine 656:Henry Wellcome 651: 648: 644:North Carolina 591: 588: 574: 573:Glaxo Wellcome 571: 569: 566: 511:mercaptopurine 484:FTSE 100 Index 411:pharmaceutical 395: 394: 383: 379: 378: 376: 375: 367: 362: 356: 354: 348: 347: 344: 341: 338: 337: 326: 318: 317: 306: 298: 297: 286: 281: 278: 277: 266: 261: 258: 257: 243: 239: 238: 236: 235: 230: 224: 222: 218: 217: 215: 214: 202: 191: 189: 186: 183: 182: 179: 176: 173: 172: 166: 162: 161: 148: 144: 143: 141: 140: 137: 136:Glaxo Wellcome 133: 131: 127: 126: 124: 123: 118: 116:Pharmaceutical 112: 110: 106: 105: 103: 102: 97: 87: 85: 80: 77: 76: 71: 67: 66: 63: 59: 58: 55: 47: 46: 43: 26: 9: 6: 4: 3: 2: 12844: 12833: 12830: 12828: 12825: 12823: 12820: 12818: 12815: 12813: 12810: 12808: 12805: 12803: 12800: 12798: 12795: 12793: 12790: 12788: 12785: 12783: 12780: 12778: 12775: 12773: 12770: 12768: 12765: 12763: 12760: 12758: 12755: 12753: 12750: 12748: 12745: 12744: 12742: 12729: 12724: 12718: 12715: 12713: 12710: 12708: 12705: 12703: 12700: 12698: 12695: 12693: 12692:J&L Steel 12690: 12688: 12685: 12683: 12680: 12678: 12675: 12673: 12670: 12668: 12665: 12663: 12660: 12658: 12655: 12653: 12650: 12648: 12645: 12643: 12640: 12639: 12637: 12633: 12627: 12624: 12622: 12619: 12617: 12614: 12612: 12609: 12607: 12604: 12602: 12599: 12598: 12596: 12590: 12584: 12581: 12579: 12576: 12574: 12571: 12569: 12566: 12564: 12561: 12559: 12556: 12554: 12551: 12550: 12548: 12544: 12538: 12535: 12533: 12530: 12529: 12527: 12523: 12517: 12514: 12512: 12511:Vocelli Pizza 12509: 12507: 12504: 12502: 12499: 12497: 12494: 12492: 12489: 12487: 12484: 12482: 12479: 12477: 12474: 12472: 12469: 12467: 12464: 12462: 12459: 12457: 12454: 12452: 12449: 12447: 12444: 12442: 12439: 12437: 12434: 12432: 12429: 12427: 12424: 12422: 12419: 12417: 12414: 12412: 12409: 12407: 12404: 12402: 12399: 12397: 12394: 12392: 12391:Consol Energy 12389: 12387: 12384: 12382: 12381:CNX Resources 12379: 12377: 12376:Calgon Carbon 12374: 12372: 12369: 12367: 12364: 12362: 12359: 12357: 12354: 12352: 12349: 12347: 12344: 12342: 12339: 12337: 12334: 12332: 12329: 12327: 12324: 12323: 12321: 12317: 12311: 12308: 12306: 12303: 12302: 12300: 12294: 12288: 12285: 12283: 12280: 12278: 12275: 12273: 12270: 12268: 12265: 12263: 12260: 12258: 12255: 12253: 12250: 12249: 12247: 12244: 12242: 12237: 12233: 12229: 12222: 12217: 12215: 12210: 12208: 12203: 12202: 12199: 12186: 12185:Flowers Foods 12182: 12179: 12176: 12172: 12169: 12166: 12162: 12159: 12156: 12155:Liberty Media 12152: 12149: 12146: 12142: 12139: 12136: 12132: 12129: 12126: 12123: 12120: 12116: 12113: 12110: 12106: 12103: 12100: 12096: 12093: 12090: 12086: 12083: 12080: 12076: 12075:Colonial Penn 12073: 12070: 12066: 12063: 12060: 12056: 12053: 12052: 12050: 12042: 12036: 12033: 12031: 12028: 12026: 12023: 12021: 12018: 12016: 12013: 12011: 12008: 12006: 12003: 12001: 11998: 11996: 11993: 11991: 11988: 11986: 11983: 11981: 11978: 11976: 11973: 11972: 11970: 11962: 11956: 11953: 11951: 11948: 11946: 11943: 11941: 11938: 11936: 11933: 11931: 11928: 11926: 11923: 11921: 11918: 11916: 11915:Triumph Group 11913: 11911: 11910:Toll Brothers 11908: 11906: 11903: 11901: 11898: 11896: 11893: 11891: 11888: 11886: 11883: 11881: 11878: 11876: 11873: 11871: 11868: 11866: 11863: 11861: 11858: 11856: 11853: 11851: 11848: 11846: 11843: 11841: 11838: 11836: 11833: 11831: 11828: 11826: 11823: 11821: 11818: 11816: 11813: 11811: 11808: 11806: 11803: 11801: 11798: 11796: 11793: 11791: 11788: 11786: 11783: 11781: 11778: 11777: 11775: 11769: 11763: 11760: 11758: 11755: 11753: 11750: 11748: 11745: 11743: 11740: 11738: 11735: 11733: 11730: 11728: 11725: 11723: 11720: 11718: 11717:Ballard Spahr 11715: 11714: 11712: 11706: 11700: 11697: 11695: 11692: 11690: 11687: 11685: 11682: 11680: 11677: 11675: 11672: 11670: 11667: 11665: 11662: 11660: 11657: 11655: 11652: 11651: 11649: 11643: 11636: 11633: 11630: 11627: 11624: 11623:Campbell Soup 11621: 11618: 11615: 11612: 11609: 11606: 11603: 11600: 11597: 11596: 11594: 11589:corporations 11587: 11583: 11579: 11572: 11569: 11566: 11563: 11560: 11557: 11556: 11554: 11549:corporations 11547: 11543: 11539: 11535: 11534: 11528: 11523: 11519: 11512: 11507: 11505: 11500: 11498: 11493: 11492: 11489: 11477: 11474: 11472: 11469: 11467: 11464: 11462: 11459: 11457: 11454: 11452: 11449: 11447: 11444: 11442: 11439: 11437: 11434: 11432: 11431:Taylor Wimpey 11429: 11427: 11424: 11422: 11419: 11417: 11414: 11412: 11409: 11407: 11404: 11402: 11399: 11397: 11394: 11392: 11389: 11387: 11384: 11382: 11379: 11377: 11374: 11372: 11369: 11367: 11364: 11362: 11359: 11357: 11354: 11352: 11349: 11347: 11344: 11342: 11339: 11337: 11334: 11332: 11329: 11327: 11326:Phoenix Group 11324: 11322: 11319: 11317: 11314: 11312: 11309: 11307: 11304: 11302: 11301:NatWest Group 11299: 11297: 11296:National Grid 11294: 11292: 11289: 11287: 11284: 11282: 11279: 11277: 11274: 11272: 11269: 11267: 11264: 11262: 11259: 11257: 11254: 11252: 11249: 11247: 11244: 11242: 11239: 11237: 11234: 11232: 11229: 11227: 11224: 11222: 11219: 11217: 11214: 11212: 11209: 11207: 11204: 11202: 11199: 11197: 11194: 11192: 11189: 11187: 11184: 11182: 11179: 11177: 11174: 11172: 11169: 11167: 11164: 11162: 11159: 11157: 11154: 11152: 11151:Frasers Group 11149: 11147: 11144: 11142: 11139: 11137: 11134: 11132: 11129: 11127: 11124: 11122: 11119: 11117: 11114: 11112: 11109: 11107: 11104: 11102: 11099: 11097: 11094: 11092: 11091:Compass Group 11089: 11087: 11086:Coca-Cola HBC 11084: 11082: 11079: 11077: 11074: 11072: 11069: 11067: 11064: 11062: 11059: 11057: 11054: 11052: 11049: 11047: 11044: 11042: 11039: 11037: 11034: 11032: 11029: 11027: 11024: 11022: 11019: 11017: 11014: 11012: 11009: 11007: 11006:Ashtead Group 11004: 11002: 10999: 10997: 10994: 10992: 10991:Airtel Africa 10989: 10987: 10986:Admiral Group 10984: 10982: 10979: 10978: 10975: 10970: 10965: 10960: 10951: 10946: 10944: 10939: 10937: 10932: 10931: 10928: 10916: 10908: 10907: 10904: 10898: 10895: 10893: 10890: 10888: 10885: 10883: 10880: 10878: 10875: 10873: 10870: 10868: 10865: 10863: 10860: 10858: 10855: 10853: 10850: 10848: 10845: 10843: 10840: 10838: 10835: 10833: 10830: 10829: 10827: 10825: 10821: 10815: 10809: 10806: 10804: 10801: 10799: 10796: 10794: 10791: 10789: 10786: 10784: 10781: 10779: 10776: 10774: 10773:Roberts Radio 10771: 10769: 10766: 10764: 10761: 10759: 10756: 10754: 10751: 10749: 10746: 10744: 10743:Linn Products 10741: 10739: 10736: 10734: 10731: 10729: 10726: 10724: 10721: 10719: 10716: 10714: 10711: 10709: 10706: 10704: 10701: 10699: 10696: 10694: 10691: 10689: 10686: 10684: 10681: 10679: 10676: 10674: 10671: 10669: 10666: 10664: 10661: 10659: 10656: 10654: 10651: 10649: 10646: 10645: 10643: 10641: 10637: 10631: 10625: 10622: 10620: 10617: 10615: 10614:William Drake 10612: 10610: 10607: 10605: 10602: 10600: 10597: 10595: 10592: 10590: 10587: 10585: 10582: 10580: 10577: 10575: 10572: 10570: 10567: 10565: 10562: 10560: 10557: 10555: 10552: 10550: 10547: 10545: 10542: 10540: 10537: 10535: 10532: 10530: 10527: 10525: 10522: 10520: 10519:Roberts Radio 10517: 10515: 10514:Richer Sounds 10512: 10510: 10507: 10505: 10502: 10500: 10497: 10495: 10492: 10490: 10487: 10485: 10482: 10480: 10477: 10475: 10472: 10470: 10467: 10465: 10462: 10460: 10457: 10455: 10452: 10450: 10447: 10445: 10442: 10440: 10437: 10435: 10432: 10430: 10427: 10425: 10422: 10420: 10417: 10415: 10412: 10410: 10407: 10405: 10402: 10400: 10397: 10395: 10392: 10390: 10387: 10385: 10382: 10380: 10377: 10375: 10372: 10370: 10367: 10365: 10362: 10360: 10357: 10355: 10352: 10350: 10347: 10345: 10342: 10340: 10337: 10335: 10332: 10330: 10327: 10325: 10322: 10320: 10317: 10315: 10312: 10310: 10307: 10305: 10302: 10300: 10297: 10295: 10292: 10290: 10287: 10285: 10282: 10280: 10277: 10275: 10272: 10270: 10267: 10265: 10262: 10260: 10257: 10255: 10252: 10250: 10247: 10245: 10242: 10240: 10237: 10235: 10232: 10231: 10229: 10227: 10221: 10216: 10209: 10202: 10191: 10190: 10188: 10186: 10180: 10176: 10169: 10164: 10162: 10157: 10155: 10150: 10149: 10146: 10134: 10133: 10124: 10123: 10120: 10114: 10111: 10109: 10106: 10104: 10101: 10099: 10096: 10094: 10091: 10089: 10086: 10084: 10081: 10079: 10076: 10075: 10073: 10069: 10063: 10062: 10058: 10055: 10054: 10050: 10048: 10047: 10043: 10041: 10040: 10036: 10034: 10033: 10029: 10027: 10026: 10022: 10020: 10019: 10015: 10012: 10011: 10007: 10005: 10004: 10000: 9999: 9997: 9993: 9987: 9984: 9982: 9979: 9977: 9974: 9972: 9969: 9967: 9964: 9962: 9959: 9957: 9954: 9952: 9949: 9948: 9946: 9940: 9934: 9931: 9929: 9926: 9924: 9921: 9919: 9916: 9914: 9911: 9909: 9906: 9904: 9901: 9899: 9896: 9894: 9891: 9889: 9886: 9885: 9883: 9877: 9867: 9864: 9862: 9859: 9857: 9854: 9852: 9849: 9847: 9844: 9842: 9839: 9837: 9834: 9832: 9829: 9827: 9824: 9822: 9819: 9817: 9814: 9812: 9809: 9807: 9804: 9802: 9801:Beecham Group 9799: 9797: 9794: 9792: 9789: 9788: 9786: 9782: 9776: 9773: 9771: 9768: 9766: 9763: 9761: 9758: 9756: 9753: 9751: 9748: 9746: 9743: 9741: 9738: 9736: 9733: 9731: 9728: 9726: 9723: 9721: 9718: 9716: 9713: 9711: 9708: 9706: 9703: 9701: 9698: 9696: 9695:GE HealthCare 9693: 9691: 9688: 9686: 9683: 9681: 9678: 9674: 9669: 9666: 9664: 9661: 9659: 9656: 9654: 9651: 9650: 9648: 9644: 9641: 9639: 9635: 9629: 9626: 9624: 9621: 9620: 9617: 9613: 9608: 9599: 9594: 9592: 9587: 9585: 9580: 9579: 9576: 9564: 9563: 9554: 9553: 9550: 9544: 9541: 9539: 9538: 9534: 9532: 9529: 9527: 9524: 9523: 9521: 9517: 9511: 9510: 9506: 9504: 9503: 9499: 9497: 9496: 9492: 9490: 9489: 9485: 9483: 9482: 9478: 9477: 9475: 9471: 9461: 9458: 9456: 9453: 9451: 9448: 9446: 9445:John K. Smith 9443: 9441: 9438: 9436: 9433: 9431: 9428: 9427: 9425: 9421: 9415: 9412: 9410: 9407: 9405: 9402: 9400:Jesse Goodman 9399: 9397: 9394: 9392: 9389: 9387: 9384: 9382: 9379: 9377: 9374: 9372: 9369: 9367: 9366:Emma Walmsley 9364: 9362: 9359: 9358: 9356: 9350: 9347: 9343: 9333: 9330: 9328: 9325: 9323: 9320: 9318: 9315: 9313: 9310: 9308: 9305: 9303: 9300: 9298: 9295: 9293: 9290: 9288: 9285: 9283: 9280: 9277: 9275: 9272: 9270: 9267: 9265: 9262: 9260: 9257: 9255: 9252: 9250: 9247: 9245: 9242: 9240: 9237: 9235: 9232: 9229: 9227: 9224: 9223: 9221: 9217: 9207: 9206: 9201: 9198: 9196: 9193: 9191: 9188: 9186: 9183: 9181: 9178: 9176: 9173: 9171: 9168: 9166: 9163: 9161: 9158: 9156: 9153: 9151: 9148: 9146: 9143: 9141: 9138: 9136: 9133: 9131: 9128: 9126: 9123: 9121: 9118: 9116: 9113: 9111: 9108: 9106: 9103: 9102: 9100: 9096: 9090: 9089: 9084: 9081: 9079: 9076: 9074: 9071: 9069: 9066: 9064: 9061: 9059: 9058:Paxil/Seroxat 9056: 9054: 9051: 9049: 9046: 9044: 9041: 9039: 9036: 9034: 9031: 9029: 9026: 9024: 9021: 9019: 9016: 9014: 9011: 9010: 9008: 9004: 9001: 8997: 8994: 8990: 8984: 8981: 8979: 8976: 8974: 8971: 8969: 8966: 8964: 8961: 8959: 8956: 8954: 8951: 8949: 8946: 8944: 8941: 8939: 8936: 8934: 8933:Beecham Group 8931: 8929: 8926: 8925: 8923: 8919:Predecessors, 8917: 8909: 8905: 8901: 8894: 8891: 8889: 8886: 8884: 8881: 8879: 8876: 8874: 8871: 8870: 8868: 8864: 8861: 8857: 8853: 8846: 8841: 8839: 8834: 8832: 8827: 8826: 8823: 8817: 8813: 8810: 8805: 8802: 8800: 8797: 8795: 8792: 8790: 8787: 8785: 8782: 8781: 8778: 8776: 8772: 8767: 8766: 8745: 8741: 8740: 8735: 8728: 8712: 8708: 8707:The Telegraph 8703: 8696: 8680: 8676: 8672: 8665: 8649: 8645: 8641: 8634: 8627: 8623: 8620: 8615: 8608: 8604: 8601: 8596: 8577: 8570: 8564: 8545: 8541: 8537: 8531: 8523: 8519: 8514: 8509: 8505: 8501: 8497: 8493: 8489: 8482: 8466: 8462: 8458: 8451: 8443: 8439: 8434: 8426: 8410: 8406: 8405:The Telegraph 8402: 8395: 8387: 8383: 8382: 8377: 8370: 8364: 8361: 8357: 8352: 8344: 8343: 8338: 8334: 8331: 8327: 8326: 8321: 8317: 8314: 8308: 8292: 8288: 8284: 8269: 8265: 8261: 8254: 8247: 8242: 8240: 8233: 8232: 8227: 8223: 8220: 8214: 8206: 8200: 8192: 8186: 8178: 8174: 8170: 8166: 8160: 8153: 8147: 8128: 8124: 8120: 8116: 8112: 8108: 8104: 8097: 8093: 8087: 8081: 8079: 8075: 8072: 8066: 8062: 8058: 8054: 8048: 8044: 8040: 8037: 8033: 8029: 8026: 8021: 8013: 8009: 8005: 8001: 7996: 7991: 7987: 7983: 7979: 7972: 7963: 7955: 7951: 7946: 7941: 7937: 7933: 7929: 7925: 7921: 7914: 7912: 7905: 7903: 7902: 7897: 7892: 7891: 7886: 7882: 7879: 7875: 7871: 7868: 7864: 7860: 7857: 7852: 7844: 7840: 7835: 7830: 7826: 7822: 7818: 7811: 7795: 7791: 7787: 7781: 7774: 7770: 7766: 7761: 7756: 7752: 7748: 7744: 7737: 7731: 7728: 7724: 7719: 7714: 7710: 7706: 7703:(7): 824–31. 7702: 7698: 7694: 7686: 7682: 7677: 7672: 7668: 7664: 7660: 7653: 7649: 7644: 7639: 7635: 7631: 7627: 7619: 7614: 7610: 7606: 7602: 7595: 7588: 7584: 7581: 7567: 7563: 7557: 7555: 7546: 7542: 7538: 7532: 7525: 7521: 7518: 7514: 7509: 7503: 7501: 7500: 7495: 7489: 7485: 7482: 7478: 7474: 7471: 7466: 7464: 7447: 7443: 7442: 7437: 7430: 7414: 7410: 7409: 7404: 7397: 7390: 7386: 7382: 7377: 7372: 7368: 7364: 7360: 7353: 7347: 7336: 7332: 7328: 7321: 7317: 7312: 7307: 7303: 7299: 7295: 7288: 7284: 7280: 7276: 7272: 7268: 7264: 7260: 7252: 7250: 7240: 7236: 7231: 7226: 7222: 7218: 7214: 7207: 7205: 7198: 7195: 7191: 7186: 7181: 7178:(6): 679–84. 7177: 7173: 7169: 7162: 7161: 7156: 7152: 7149: 7145: 7141: 7136: 7117: 7113: 7109: 7103: 7096: 7092: 7089: 7084: 7077: 7074:Jim Edwards, 7071: 7067: 7064: 7060: 7056: 7051: 7035: 7031: 7024: 7007: 7003: 6997: 6981: 6977: 6973: 6967: 6951: 6947: 6943: 6937: 6921: 6917: 6913: 6907: 6900: 6896: 6893: 6888: 6872: 6868: 6864: 6858: 6850: 6846: 6845: 6840: 6833: 6831: 6814: 6810: 6806: 6800: 6794: 6792: 6788: 6782: 6778: 6774: 6771: 6768:Tony Jaques, 6757: 6753: 6752: 6747: 6740: 6724: 6720: 6719:The Telegraph 6716: 6709: 6703: 6701: 6697: 6693: 6690: 6685: 6684: 6679: 6675: 6672: 6666: 6658: 6656:9781590318676 6652: 6648: 6641: 6634: 6630: 6627: 6625: 6619: 6611: 6609:9780195337198 6605: 6601: 6594: 6578: 6574: 6570: 6566: 6559: 6557: 6555: 6553: 6551: 6542: 6538: 6534: 6528: 6526: 6524: 6522: 6505: 6501: 6497: 6490: 6474: 6470: 6469:Fierce Pharma 6466: 6459: 6452: 6451: 6446: 6441: 6433: 6429: 6425: 6419: 6411: 6407: 6403: 6397: 6381: 6377: 6373: 6367: 6361: 6357: 6354: 6348: 6332: 6328: 6324: 6320: 6316: 6309: 6298: 6291: 6285: 6279: 6268: 6264: 6260: 6245: 6241: 6235: 6227: 6223: 6217: 6210: 6206: 6203: 6197: 6186: 6179: 6173: 6165: 6161: 6157: 6153: 6149: 6145: 6138: 6130: 6126: 6122: 6118: 6114: 6110: 6106: 6105:J. Med. Virol 6099: 6091: 6087: 6082: 6077: 6073: 6069: 6066:(8): 1122–4. 6065: 6061: 6057: 6050: 6042: 6038: 6034: 6028: 6020: 6016: 6012: 6006: 5998: 5994: 5990: 5983: 5975: 5971: 5967: 5963: 5959: 5955: 5951: 5947: 5940: 5938: 5929: 5925: 5918: 5910: 5906: 5902: 5896: 5890: 5886: 5882: 5877: 5861: 5857: 5853: 5846: 5838: 5832: 5828: 5827: 5819: 5811: 5807: 5806: 5801: 5797: 5791: 5783: 5779: 5773: 5765: 5761: 5757: 5753: 5749: 5745: 5738: 5722: 5718: 5712: 5704: 5700: 5699: 5694: 5687: 5685: 5676: 5672: 5668: 5664: 5660: 5656: 5652: 5648: 5641: 5639: 5630: 5626: 5620: 5618: 5616: 5614: 5597: 5593: 5589: 5583: 5581: 5572: 5568: 5564: 5560: 5556: 5552: 5549:(2): 105–61. 5548: 5544: 5537: 5521: 5517: 5513: 5507: 5499: 5495: 5491: 5487: 5480: 5472: 5468: 5464: 5460: 5456: 5452: 5445: 5437: 5433: 5427: 5411: 5407: 5401: 5393: 5389: 5383: 5368: 5364: 5358: 5343: 5339: 5333: 5317: 5313: 5307: 5299: 5293: 5285: 5279: 5263: 5259: 5252: 5236: 5232: 5226: 5210: 5206: 5202: 5195: 5187: 5183: 5179: 5172: 5155: 5150: 5146: 5140: 5132: 5128: 5124: 5117: 5101: 5097: 5093: 5086: 5070: 5066: 5062: 5055: 5053: 5036: 5032: 5028: 5021: 5013: 5009: 5005: 4998: 4982: 4978: 4974: 4968: 4952: 4948: 4944: 4937: 4921: 4917: 4913: 4906: 4890: 4886: 4882: 4876: 4860: 4856: 4849: 4833: 4829: 4825: 4818: 4816: 4799: 4795: 4791: 4785: 4783: 4774: 4770: 4766: 4760: 4744: 4740: 4739:The Telegraph 4735: 4727: 4711: 4707: 4703: 4696: 4680: 4676: 4675:The Telegraph 4672: 4665: 4649: 4645: 4641: 4635: 4627: 4623: 4619: 4613: 4597: 4593: 4592: 4586: 4578: 4562: 4558: 4557: 4552: 4545: 4529: 4525: 4521: 4514: 4498: 4494: 4490: 4486: 4482: 4475: 4473: 4471: 4454: 4450: 4446: 4439: 4433: 4429: 4425: 4422: 4416: 4410: 4406: 4402: 4399: 4393: 4377: 4373: 4369: 4363: 4355: 4351: 4347: 4340: 4332: 4328: 4324: 4317: 4301: 4297: 4293: 4287: 4278: 4273: 4269: 4262: 4254: 4248: 4240: 4236: 4230: 4222: 4218: 4213: 4205: 4198: 4194: 4190: 4186: 4183: 4178: 4172: 4168: 4164: 4159: 4143: 4139: 4135: 4119: 4115: 4111: 4104: 4088: 4084: 4083:The Telegraph 4080: 4074: 4066: 4060: 4052: 4048: 4041: 4033: 4027: 4011: 4005: 3997: 3993: 3988: 3981: 3973: 3969: 3965: 3961: 3956: 3951: 3948:(6783): 258. 3947: 3943: 3939: 3932: 3924: 3920: 3919:The Economist 3916: 3910: 3894: 3890: 3886: 3882: 3881: 3876: 3869: 3853: 3849: 3846: 3840: 3824: 3820: 3816: 3812: 3811: 3806: 3799: 3791: 3785: 3781: 3774: 3766: 3762: 3758: 3752: 3744: 3740: 3736: 3730: 3722: 3718: 3714: 3708: 3692: 3688: 3687: 3682: 3676: 3668: 3664: 3660: 3653: 3645: 3641: 3637: 3630: 3622: 3618: 3614: 3607: 3596: 3589: 3582: 3574: 3570: 3569: 3564: 3557: 3555: 3546: 3540: 3536: 3529: 3513: 3509: 3508: 3503: 3496: 3480: 3476: 3472: 3465: 3458: 3454: 3451: 3446: 3439: 3435: 3429: 3422: 3418: 3414: 3411: 3406: 3395: 3388: 3382: 3374: 3368: 3364: 3357: 3355: 3347: 3341: 3334: 3328: 3321: 3315: 3299: 3295: 3294:"GSK History" 3289: 3287: 3285: 3283: 3281: 3279: 3267: 3263: 3256: 3249: 3247: 3245: 3243: 3235: 3229: 3222: 3216: 3210: 3208: 3207: 3202: 3196: 3195: 3190: 3186: 3183: 3179: 3175: 3172: 3167: 3165: 3163: 3161: 3159: 3157: 3155: 3153: 3151: 3149: 3147: 3137: 3132: 3128: 3124: 3118: 3116: 3109: 3098: 3094: 3093: 3088: 3072: 3068: 3067: 3061: 3053: 3051: 3049: 3032: 3028: 3022: 3006: 3002: 3001: 2996: 2990: 2974: 2970: 2966: 2960: 2944: 2940: 2936: 2930: 2914: 2913:"At a glance" 2908: 2889: 2883: 2881: 2879: 2877: 2875: 2870: 2855: 2850: 2843: 2839: 2838:Beecham Group 2833: 2829: 2821: 2818: 2786: 2783: 2781: 2778: 2776: 2773: 2771: 2768: 2767: 2763: 2752: 2745: 2744:unnecessary. 2741: 2739: 2735: 2731: 2726: 2724: 2718: 2716: 2708:Miscellaneous 2705: 2699: 2695: 2691: 2687: 2673: 2659: 2649: 2647: 2643: 2639: 2635: 2625: 2621: 2619: 2615: 2614: 2609: 2605: 2601: 2595: 2588: 2580: 2576: 2571: 2561: 2557: 2555: 2550: 2546: 2545:boxed warning 2542: 2541:Steven Nissen 2538: 2534: 2533: 2527: 2520: 2519:meta-analyses 2516: 2512: 2508: 2507:heart failure 2504: 2500: 2499: 2494: 2490: 2485: 2478: 2474: 2473:rosiglitazone 2467: 2466:Rosiglitazone 2463: 2458: 2454: 2444: 2442: 2438: 2433: 2430: 2426: 2421: 2419: 2415: 2412:), Lotronex ( 2411: 2407: 2403: 2399: 2395: 2391: 2390:rosiglitazone 2387: 2383: 2378: 2376: 2372: 2360: 2341: 2339: 2335: 2330: 2325: 2322: 2318: 2314: 2310: 2306: 2302: 2299: 2298: 2287: 2278: 2276: 2272: 2268: 2249: 2243: 2239: 2235: 2230: 2228: 2224: 2220: 2216: 2212: 2208: 2194: 2183: 2169: 2167: 2166: 2161: 2160: 2154: 2152: 2147: 2143: 2139: 2127:Controversies 2124: 2120: 2118: 2113: 2109: 2104: 2102: 2098: 2093: 2083: 2079: 2071: 2067: 2059: 2054: 2052: 2048: 2044: 2040: 2027: 2023: 2019: 2016: 2013: 2009: 2006: 2003: 1998: 1994: 1990: 1987: 1986: 1985: 1972: 1970: 1966: 1962: 1957: 1948: 1946: 1942: 1938: 1932: 1922: 1920: 1916: 1906: 1904: 1900: 1896: 1892: 1888: 1884: 1880: 1876: 1872: 1868: 1864: 1860: 1846: 1834: 1832: 1828: 1824: 1820: 1816: 1806: 1804: 1799: 1797: 1793: 1789: 1788:pyrimethamine 1785: 1781: 1777: 1773: 1769: 1765: 1761: 1757: 1753: 1749: 1745: 1741: 1737: 1733: 1729: 1725: 1724:HIV infection 1721: 1717: 1713: 1709: 1705: 1701: 1689: 1668: 1662: 1656: 1650: 1644: 1639: 1636: 1630: 1625: 1622: 1616: 1610: 1604: 1599: 1596: 1590: 1585: 1582: 1570: 1564: 1563: 1558: 1550: 1547:(Merged 1978) 1544: 1539: 1536: 1533: 1532: 1530:(Merged 1995) 1527: 1526: 1524: 1514: 1509: 1504:C.L. Bencard 1503: 1498: 1495: 1494: 1492: 1491: 1489:(Merged 1989) 1486: 1485:Beecham Group 1483: 1475: 1469: 1461: 1455: 1454: 1450: 1447: 1440: 1437: 1432: 1426: 1425: 1421: 1418: 1417: 1412: 1411: 1406: 1405: 1400: 1399: 1397: 1396: 1395: 1392: 1391: 1379: 1377: 1372: 1369: 1367: 1363: 1359: 1355: 1350: 1347: 1344: 1342: 1332: 1329: 1327: 1322: 1320: 1310: 1301: 1290: 1280: 1275:billion (£9.2 1270: 1260: 1258: 1253: 1248:billion (€955 1243: 1239: 1235: 1231: 1227: 1222: 1220: 1216: 1209:, for US$ 5.1 1208: 1204: 1191: 1187: 1179: 1175: 1171: 1167: 1166:rare diseases 1162: 1159: 1157: 1153: 1152:Emma Walmsley 1148: 1146: 1142: 1138: 1132: 1128: 1124: 1111: 1102: 1100: 1096: 1092: 1088: 1084: 1080: 1076: 1072: 1068: 1064: 1056: 1048: 1044: 1036: 1028: 1024: 1020: 1016: 1012: 1008: 1000: 990: 980: 976: 968: 963: 961: 957: 953: 949: 940:in 2001, for 939: 931: 927: 918: 912: 908: 897: 895: 891: 887: 877: 875: 870: 868: 864: 860: 856: 852: 851:John K. Smith 847: 837: 835: 831: 827: 823: 822:Beecham Group 819: 816:launched his 815: 808: 804: 799: 794: 793:Beecham Group 779: 777: 774:, London and 773: 769: 765: 761: 757: 753: 749: 744: 742: 738: 734: 733:Hertfordshire 730: 719: 717: 713: 708: 704: 700: 695: 693: 689: 685: 681: 677: 673: 669: 665: 661: 657: 647: 645: 641: 637: 633: 629: 625: 615: 611: 609: 605: 601: 597: 584: 579: 565: 563: 559: 551: 547: 543: 539: 535: 531: 527: 522: 520: 516: 515:pyrimethamine 512: 508: 504: 500: 496: 491: 489: 485: 481: 476: 474: 470: 466: 462: 458: 454: 450: 446: 442: 438: 436: 430: 428: 424: 420: 416: 412: 409: 408:multinational 405: 401: 392: 384: 380: 371: 368: 366: 363: 361: 358: 357: 355: 353: 349: 346:70,000 (2024) 345: 339: 327: 324: 319: 307: 304: 299: 287: 284: 279: 267: 264: 259: 253: 244: 240: 234: 231: 229: 226: 225: 223: 219: 211: 206: 205:Emma Walmsley 203: 199: 193: 192: 190: 184: 180: 174: 171:, England, UK 170: 167: 163: 149: 145: 138: 135: 134: 132: 128: 122: 121:Biotechnology 119: 117: 114: 113: 111: 107: 101: 98: 96: 92: 89: 88: 86: 83: 78: 75: 72: 68: 64: 60: 53: 48: 41: 36: 30: 19: 12717:Westinghouse 12672:Integra Bank 12562: 12558:FedEx Ground 12486:PTC Alliance 12245:headquarters 12240: 12181:Tasty Baking 12165:Dow Chemical 12095:GSI Commerce 11999: 11860:EPAM Systems 11800:Aqua America 11790:AlliedBarton 11742:Duane Morris 11694:Radian Group 11542:Philadelphia 11531: 11416:Spirax Group 11411:Smiths Group 11391:Severn Trent 11165: 10892:Penhaligon's 10823: 10758:Penhaligon's 10658:Aston Martin 10639: 10484:Molton Brown 10388: 10130: 10059: 10053:Side Effects 10051: 10044: 10037: 10030: 10023: 10016: 10008: 10001: 9942:Industry and 9830: 9816:Chiroscience 9704: 9561: 9537:Side Effects 9535: 9507: 9500: 9493: 9486: 9479: 9455:Andrew Witty 9440:Mahlon Kline 9391:Vivienne Cox 9204: 9160:H5N1 vaccine 9087: 8921:acquisitions 8859:Subsidiaries 8851: 8748:. Retrieved 8737: 8727: 8715:. Retrieved 8706: 8695: 8683:. Retrieved 8674: 8664: 8652:. Retrieved 8644:The Guardian 8643: 8633: 8614: 8595: 8583:. Retrieved 8563: 8551:. Retrieved 8539: 8530: 8495: 8491: 8481: 8469:. Retrieved 8461:The Guardian 8460: 8450: 8437: 8425: 8415:11 September 8413:. Retrieved 8404: 8394: 8379: 8369: 8355: 8346: 8342:The Guardian 8340: 8325:The Guardian 8323: 8307: 8295:. Retrieved 8286: 8272:. Retrieved 8263: 8253: 8228: 8213: 8185: 8172: 8159: 8151: 8146: 8134:. Retrieved 8106: 8102: 8086: 8069: 8056: 8052: 8046: 8020: 7985: 7981: 7971: 7962: 7927: 7923: 7899: 7894: 7888: 7851: 7824: 7820: 7810: 7800:11 September 7798:. Retrieved 7789: 7780: 7772: 7750: 7746: 7736: 7700: 7697:Eur. Heart J 7696: 7689: 7666: 7663:Eur. Heart J 7662: 7636:(7): 773–6. 7633: 7630:Eur. Heart J 7629: 7608: 7604: 7594: 7570:. Retrieved 7545:the original 7540: 7531: 7513:David Graham 7508: 7499:The Guardian 7497: 7491: 7450:. Retrieved 7439: 7429: 7417:. Retrieved 7406: 7396: 7388: 7366: 7362: 7352: 7339:. Retrieved 7330: 7324: 7301: 7298:Diabetologia 7297: 7262: 7258: 7220: 7216: 7175: 7171: 7164: 7158: 7135: 7125:11 September 7123:. Retrieved 7111: 7102: 7083: 7050: 7038:. Retrieved 7023: 7010:. Retrieved 6996: 6984:. Retrieved 6980:the original 6975: 6966: 6954:. Retrieved 6950:the original 6945: 6936: 6924:. Retrieved 6915: 6906: 6887: 6875:. Retrieved 6866: 6857: 6842: 6819:11 September 6817:. Retrieved 6808: 6799: 6786: 6784: 6780: 6760:. Retrieved 6749: 6739: 6729:11 September 6727:. Retrieved 6718: 6708: 6699: 6687: 6683:The Guardian 6681: 6665: 6646: 6640: 6623: 6618: 6599: 6593: 6581:. Retrieved 6572: 6568: 6536: 6508:. Retrieved 6499: 6489: 6477:. Retrieved 6468: 6458: 6448: 6445:Ben Goldacre 6440: 6427: 6418: 6405: 6396: 6386:11 September 6384:. Retrieved 6380:the original 6375: 6366: 6347: 6337:11 September 6335:. Retrieved 6319:The Guardian 6318: 6308: 6297:the original 6284: 6271:. Retrieved 6262: 6256: 6248:. Retrieved 6244:the original 6234: 6226:the original 6216: 6196: 6185:the original 6172: 6150:(9): 961–5. 6147: 6143: 6137: 6104: 6098: 6063: 6059: 6049: 6036: 6027: 6014: 6005: 5992: 5982: 5952:(4): 77–87. 5949: 5945: 5917: 5904: 5895: 5876: 5866:11 September 5864:. Retrieved 5855: 5845: 5825: 5818: 5803: 5796:McNeil DG Jr 5790: 5782:the original 5772: 5747: 5743: 5737: 5725:. Retrieved 5711: 5696: 5650: 5646: 5602:11 September 5600:. Retrieved 5591: 5546: 5542: 5536: 5524:. Retrieved 5515: 5506: 5489: 5485: 5479: 5454: 5450: 5444: 5436:the original 5426: 5414:. Retrieved 5409: 5400: 5391: 5382: 5370:. Retrieved 5366: 5357: 5345:. Retrieved 5341: 5332: 5320:. Retrieved 5315: 5306: 5292: 5266:. Retrieved 5261: 5251: 5239:. Retrieved 5225: 5213:. Retrieved 5209:the original 5204: 5194: 5186:the original 5181: 5171: 5159:. Retrieved 5154:the original 5148: 5139: 5131:the original 5126: 5116: 5104:. Retrieved 5095: 5085: 5073:. Retrieved 5069:the original 5064: 5039:. 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