Duffy antigen system

2242: 301: 278: 2068:

with African ancestry often have healthy Duffy-null antigen-associated neutrophil counts instead of neutropenia has historically contributed to inequity in access to medications that require blood monitoring due to risk of neutropenia, including chemotherapy and the antipsychotic medication clozapine. The lower number of circulating neutrophils can cause individuals with the Duffy-null genotype to fall below what typically would be considered safe to continue these treatments, despite new data showing that neutrophil functioning is preserved in these individuals.

200: 175: 307: 206: 2124:, despite the (on average) lower white cell counts found in black Africans. This difference appears to correlate with a particular genotype (-46C/C) associated with the absence of the Duffy antigen. This genotype has only been found in black Africans and their descendants. The strength of this association increases inversely with the total white cell count. The basis for this association is probably related to the role of the Duffy antigen in 2051:. The absence of erythroid DARC alters hematopoiesis including stem and progenitor cells, which ultimately gives rise to phenotypically distinct neutrophils. As a result, mature neutrophils of Duffy-negative individuals carry more molecular "weapons" against infectious pathogens. Therefore, alternative physiological patterns of hematopoiesis and bone marrow cell outputs depend on the expression of DARC in the erythroid lineage. 1977:, Brazil, made by the doctor Sérgio Albuquerque, suggests that the genotypes FY*A/FY*B-33 and FY*B/FY*B-33 (where -33 refers to the null mutation at position -33 in the GATA box) may have an advantage over the genotypes FY*A/FY*B and FY*A/FY*A, FY*A/FY*B, FY*A/FY*X and FY*B/FY*X. FY*A/FY*B and FY*A/FY*A genotypes showed to be associated with increased rates of 2151:, an association of several variants in the DARC gene (coding and non-coding) correlates with increased serum levels of monocyte chemoattractant protein (MCP -1). A new variant in this population, consisting of the amino acid substitution of arginine for a cysteine at position 89 of the protein diminishes the ability to bind chemokines. 2064:

problematic as the Duffy-null genotype is common in individuals with African and certain Middle Eastern ancestries, and the term implies that individuals with European ancestry have the normal reference neutrophil count. The term "Duffy-null associated neutrophil count" (DANC) has been proposed as a replacement.

1686:

genotype, but has since been described in Brazilians. However, the study's authors point out that the Brazilian population has arisen from intermarriage between Portuguese, Black Africans, and Indians, which accounts for the presence of this mutation in a few members of Brazil's non-White groups. Two

2296:

Anti-Fy is a common antibody while anti-Fy is approximately 20 times less common., They are reactive at body temperature and are therefore clinically significant, although they do not typically bind complement. Antibodies are acquired through exposure (pregnancy or history of blood transfusion) and

1440:

Biochemical analysis of the Duffy antigen has shown that it has a high content of α-helical secondary structure - typical of chemokine receptors. Its N-glycans are mostly of the triantennary complex type terminated with α2-3- and α2-6-linked sialic acid residues with bisecting GlcNAc and α1-6-linked

1410:

The mouse ortholog has been cloned and exhibits 63% homology to the human gene at the amino acid level. The mouse gene is located on chromosome 1 between the genetic markers Xmv41 and D1Mit166. The mouse gene has two exons (100 and 1064 nucleotides in length), separated by a 461 base pair intron. In

2195:

Experimental work has suggested that DARC expression inhibits prostate tumor growth. Men of black African descent are at greater risk of prostate cancer than are men of either European or Asian descendant (60% greater incidence and double the mortality compared to Whites). However, the contribution

2063:

count than the typical laboratory normal range, but the lower amount of circulating neutrophils associated with this genotype does not seem to confer an increased risk of infection. Clinical use of the term "benign ethnic neutropenic" to describe this phenomenon remains widespread, but the term is

1177:

Several other types were later discovered bringing the current total up to 6: Fya, Fyb, Fy3, Fy4, Fy5 and Fy6. Only Fya, Fyb and Fy3 are considered clinically important. Reactions to Fy5 have also rarely been reported. The Fy4 antigen, originally described on Fy (a–b–) RBCs, is now thought to be a

2067:

The distinctive neutrophils that are formed in the absence of DARC on erythroid lineage (see above - role of DARC on hematopoiesis) readily leave the blood stream, which explains the apparent lower numbers of neutrophils in the blood of Duffy-null individuals. Failure to recognize that individuals

4000:

Middleton J, Americh L, Gayon R, Julien D, Mansat M, Mansat P, Anract P, Cantagrel A, Cattan P, Reimund JM, Aguilar L, Amalric F, Girard JP (2005). "A comparative study of endothelial cell markers expressed in chronically inflamed human tissues: MECA-79, Duffy antigen receptor for chemokines, von

1560:

that is known to be associated with G-protein signaling. Consistent with this finding ligand binding by DARC does not induce G-protein coupled signal transduction nor a Ca2+ flux unlike other chemokine receptors. Based on these alignments the Duffy antigen is considered to be most similar to the

1475:

of some organs including the spleen, liver and kidney and the large pulmonary venules. Duffy antigen has then a very unique cell expression profile in cerebellar neurons, venular endothelial cells and erythroid cells. In some people who lack the Duffy antigen on their erythrocytes it is still

1347:

The silent allele has evolved at least twice in the black population of Africa and evidence for selection for this allele has been found. The selection pressure involved here appears to be more complex than many text books might suggest. An independent evolution of this phenotype occurred in

1406:

Three exons are present in humans and chimpanzees, whereas only two exons occur in the other species. This additional exon is located at the 5' end and is entirely non coding. Both intron and exon size vary considerably between the species examined. Between the chimpanzee and the human, 24

1800:

also found an FY*X frequency of 0.0174; FY*1 = 0.291 (expressed 0.260, silent 0.031); FY*2 = 0.709 (expressed 0.427; silent 0.282). Since the FY*2 silent is the most common allele in West Africa, its minor occurrence in the sample probably represents recent diffusion from the latter

6979:

Raeymaekers P, Van Broeckhoven C, Backhovens H, Wehnert A, Muylle L, De Jonghe P, Gheuens J, Vandenberghe A (1988). "The Duffy blood group is linked to the alpha-spectrin locus in a large pedigree with autosomal dominant inheritance of Charcot-Marie-Tooth disease type 1".

1673:

While a possible role in the protection of humans from malaria had been previously suggested, this was only confirmed clinically in 1976. Since then many surveys have been carried out to elucidate the prevalence of Duffy antigen alleles in different populations including:

50: 1571:

of competition binding studies has shown high affinity binding to the Duffy antigen with dissociation constants (KD) binding values of 24 ± 4.9, 20 ± 4.7, 41.9 ± 12.8, and 33.9 ± 7 nanoMoles for MGSA, interleukin-8, RANTES and monocyte chemotactic peptide-1 respectively.

5730:

Vergara C, Tsai YJ, Grant AV, Rafaels N, Gao L, Hand T, Stockton M, Campbell M, Mercado D, Faruque M, Dunston G, Beaty TH, Oliveira RR, Ponte EV, Cruz AA, Carvalho E, Araujo MI, Watson H, Schleimer RP, Caraballo L, Nickel RG, Mathias RA, Barnes KC (November 2008).

2105:

susceptibility and the expression of the Duffy antigen. The absence of the DARC receptor appears to increase the susceptibility to infection by HIV. However once established, the absence of the DARC receptor appears to slow down the progression of the disease.

1658:

Overall the frequencies of Fya and Fyb antigens in Whites are 66% and 83% respectively, in Asians 99% and 18.5% respectively and in blacks 10% and 23% respectively. The frequency of Fy3 is 100% Whites, 99.9% Asians and 32% Blacks. Phenotype frequencies are:

5229:

Cavasini CE, Mattos LC, Couto AA, Bonini-Domingos CR, Valencia SH, Neiras WC, Alves RT, Rossit AR, Castilho L, Machado RL (October 2007). "Plasmodium vivax infection among Duffy antigen-negative individuals from the Brazilian Amazon region: an exception?".

2259:

A Duffy negative blood recipient may have a transfusion reaction if the donor is Duffy positive. Since most Duffy-negative people are of African descent, blood donations from people of black African origin are important to transfusion banks.

2220:

tend to sustain more severe organ damage than do those with the Duffy antigen. Duffy-positive patients exhibit higher counts of white blood cells, polynuclear neutrophils, higher plasma levels of IL-8 and RANTES than Duffy-negative patients.

6834:

Nebor D, Durpes MC, Mougenel D, Mukisi-Mukaza M, Elion J, Hardy-Dessources MD, Romana M (July 2010). "Association between Duffy antigen receptor for chemokines expression and levels of inflammation markers in sickle cell anemia patients".

1138:

It was noted in the 1920s that black Africans had some intrinsic resistance to malaria, but the basis for this remained unknown. The Duffy antigen gene was the fourth gene associated with the resistance after the genes responsible for

1254:). This mutation occurs in the Fy-b allele and has been designated Fy-b (erythroid silent). Two isotypes have been identified. The Fy-x allele is characterized by a weak anti-Fy-b reaction and appears to be the result of two separate 7124:

Tournamille C, Le Van Kim C, Gane P, Le Pennec PY, Roubinet F, Babinet J, Cartron JP, Colin Y (1998). "Arg89Cys substitution results in very low membrane expression of the Duffy antigen/receptor for chemokines in Fy(x) individuals".

4128:

Chakera A, Seeber RM, John AE, Eidne KA, Greaves DR (May 2008). "The duffy antigen/receptor for chemokines exists in an oligomeric form in living cells and functionally antagonizes CCR5 signaling through hetero-oligomerization".

2305:

Typically mild but may be serious, even fatal. Although these usually occur immediately they may occur after a delay (up to 24 hours). These reactions are usually caused by anti-Fy or anti-Fy. anti-Fy3 may cause acute or delayed

1583:

cells may act as a sponge and provide a mechanism by which inflammatory chemokines may be removed from circulation as well as their concentration modified in the local environment. This hypothesis has also been questioned after

2546:

Kosaisavee V, Suwanarusk R, Chua AC, Kyle DE, Malleret B, Zhang R, Imwong M, Imerbsin R, Ubalee R, Sámano-Sánchez H, Yeung BK, Ong JJ, Lombardini E, Nosten F, Tan KS, Bifani P, Snounou G, Rénia L, Russell B (September 2017).

2154:

DARC has also been linked to rheumatoid arthritis (RA), possibly displaying chemokines such as CXCL5 on the surface of endothelial cells within the synovium, increasing the recruitment of neutrophils in the disease state.

1407:

differences in the nucleotide sequence were noted. Of these 18 occurred in non coding regions. Of the remaining 6, 3 were synonymous and 3 non synonymous mutations. The significance of these mutations if any is not known.

4600:

Chiaroni J, Touinssi M, Frassati C, Degioanni A, Gibert M, Reviron D, Mercier P, Boëtsch G (August 2004). "Genetic characterization of the population of Grande Comore Island (Njazidja) according to major blood groups".

2012:

is composed of three subdomains and is thought to function as a dimer. The critical DARC binding residues are concentrated at the dimer interface and along a relatively flat surface spanning portions of two subdomains.

5787:

Duchene J, Novitzky-Basso I, Thiriot A, Casanova-Acebes M, Bianchini M, Etheridge SL, Hub E, Nitz K, Artinger K, Eller K, Caamaño J, Rülicke T, Moss P, Megens RT, von Andrian UH, Hidalgo A, Weber C, Rot A (May 2017).

2131:

A study of 142 black South African high-risk female sex workers over 2 years revealed a seroconversion rate of 19.0%. Risk of seroconversion appeared to be correlated with Duffy-null-associated low neutrophil counts.

1588:

mice were created. These animals appeared healthy and had normal responses to infection. While the function of the Duffy antigen remains presently (2006) unknown, evidence is accumulating that suggests a role in

1194:(1.q22-1.q23) and was cloned in 1993. The gene was first localised to chromosome 1 in 1968, and was the first blood system antigen to be localised. It is a single copy gene spanning over 1500 bases and is in two 314: 213: 5016:

Ménard D, Barnadas C, Bouchier C, Henry-Halldin C, Gray LR, Ratsimbasoa A, Thonier V, Carod JF, Domarle O, Colin Y, Bertrand O, Picot J, King CL, Grimberg BT, Mercereau-Puijalon O, Zimmerman PA (March 2010).

3913:

Segerer S, Cui Y, Eitner F, Goodpaster T, Hudkins KL, Mack M, Cartron JP, Colin Y, Schlondorff D, Alpers CE (2001). "Expression of chemokines and chemokine receptors during human renal transplant rejection".

2092:

The procoagulant response to lipopolysaccharide (bacterial endotoxin) is reduced in Duffy antigen negative Africans compared with Duffy positive Whites. This difference is likely to involve additional genes.

3215:"Postcapillary venule endothelial cells in kidney express a multispecific chemokine receptor that is structurally and functionally identical to the erythroid isoform, which is the Duffy blood group antigen" 1687:

of the three Afro-Brazilian test subjects that were found to have the mutation (out of a total of 25 Afro-Brazilians tested) were also related to one another, as one was a mother and the other her daughter.

1796:(Hamitic-Semitic) speaking populations are largely Duffy-positive. Between 70%-98% of Hamito-Semitic groups in Ethiopia were found to be Duffy-positive. Serological and DNA based analysis of 115 unrelated 1842:

There appears to have been a selective sweep in Africa which reduced the incidence of this antigen there. This sweep appears to have occurred between 6,500 and 97,200 years ago (95% confidence interval)

1655:. In a sample of unrelated African Americans (n = 235), Afro-Caribbeans (n = 90) and Colombians (n = 93), the frequency of the -46T (Duffy positive) allele was 21.7%, 12.2% and 74.7% respectively. 6439:"Genome-wide association replicates the association of Duffy antigen receptor for chemokines (DARC) polymorphisms with serum monocyte chemoattractant protein-1 (MCP-1) levels in Hispanic children" 1242:

in Fy-b at position 125). A second mutation causing a Duffy negative phenotype is known: the responsible mutation is G -> A at position 298. The genetic basis for the Fy(a-b-) phenotype is a

1618:

DARC has been shown to internalise chemokines but does not scavenge them. It mediates chemokine transcytosis, which leads to apical retention of intact chemokines and more leukocyte migration.

1745:. The incidence of Fya among Ashkenazi Jews is 0.44 and among the non-Ashkenazi Jews it is 0.33. The incidence of Fyb is higher in both groups with frequencies of 0.53 and 0.64 respectively. 6791:

Afenyi-Annan A, Kail M, Combs MR, Orringer EP, Ashley-Koch A, Telen MJ (May 2008). "Lack of Duffy antigen expression is associated with organ damage in patients with sickle cell disease".

5465:

Albuquerque SR, Cavalcante Fde O, Sanguino EC, Tezza L, Chacon F, Castilho L, dos Santos MC (February 2010). "FY polymorphisms and vivax malaria in inhabitants of Amazonas State, Brazil".

2179:

The Duffy antigen is present in the normal pulmonary vascular bed. Its expression is increased in the vascular beds and alveolar septa of the lung parenchyma during suppurative pneumonia.

3121:

Woolley IJ, Hotmire KA, Sramkoski RM, Zimmerman PA, Kazura JW (August 2000). "Differential expression of the duffy antigen receptor for chemokines according to RBC age and FY genotype".

4644:

Thakral B, Saluja K, Sharma RR, Marwaha N (June 2010). "Phenotype frequencies of blood group systems (Rh, Kell, Kidd, Duffy, MNS, P, Lewis, and Lutheran) in north Indian blood donors".

2503:

Tournamille C, Colin Y, Cartron JP, Le Van Kim C (June 1995). "Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals".

2084:. In human breast cancer samples low expression of the DARC protein is significantly associated with estrogen receptor status, both lymph node and distant metastasis and poor survival. 2653:

Tournamille C, Colin Y, Cartron JP, Le Van KC (Jun 1995). "Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals".

7240:

Lachgar A, Jaureguiberry G, Le Buenac H, Bizzini B, Zagury JF, Rappaport J, Zagury D (1999). "Binding of HIV-1 to RBCs involves the Duffy antigen receptors for chemokines (DARC)".

1831:

A map of the Duffy antigen distribution has been produced. The most prevalent allele globally is FY*A. Across sub-Saharan Africa the predominant allele is the silent FY*B variant.

3718:

Dawson TC, Lentsch AB, Wang Z, Cowhig JE, Rot A, Maeda N, Peiper SC (2000). "Exaggerated response to endotoxin in mice lacking the Duffy antigen/receptor for chemokines (DARC)".

4819:

Howes RE, Patil AP, Piel FB, Nyangiri OA, Kabaria CW, Gething PW, Zimmerman PA, Barnadas C, Beall CM, Gebremedhin A, Ménard D, Williams TN, Weatherall DJ, Hay SI (April 2011).

7269:

Woolley IJ, Kalayjian R, Valdez H, Hamza N, Jacobs G, Lederman MM, Zimmerman PA (2002). "HIV nephropathy and the Duffy antigen/receptor for Chemokines in African Americans".

4446:

Das MK, Singh SS, Adak T, Vasantha K, Mohanty D (June 2005). "The Duffy blood groups of Jarawas - the primitive and vanishing tribe of Andaman and Nicobar Islands of India".

3753:

Patterson AM, Siddall H, Chamberlain G, Gardner L, Middleton J (2002). "Expression of the duffy antigen/receptor for chemokines (DARC) by the inflamed synovial endothelium".

6388:

Ramsuran V, Kulkarni H, He W, Mlisana K, Wright EJ, Werner L, Castiblanco J, Dhanda R, Le T, Dolan MJ, Guan W, Weiss RA, Clark RA, Karim SS, Ahuja SK, Ndung'u T (May 2011).

4516:

Parasol N, Cohen N, Zemishlany Z, Lerer B, Kosower NS (April 2001). "Duffy antigen/receptor for chemokines (DARC): genotypes in Ashkenazi and non-Ashkenazi Jews in Israel".

1552:. The antigen is predicted to have 7 transmembrane domains, an exocellular N-terminal domain and an endocellular C-terminal domain. Alignment with other seven transmembrane 1635:

Differences in the racial distribution of the Duffy antigens were discovered in 1954, when it was found that the overwhelming majority of people of African descent had the

6057:"A genome-wide association study in individuals of African ancestry reveals the importance of the Duffy-null genotype in the assessment of clozapine-related neutropenia" 2200:

males of black African descent. It was found that none of the increased risk could be attributed to the DARC gene. The reason for this increased risk is as yet unknown.

4253:

Nickel RG, Willadsen SA, Freidhoff LR, Huang SK, Caraballo L, Naidu RP, Levett P, Blumenthal M, Banks-Schlegel S, Bleecker E, Beaty T, Ober C, Barnes KC (August 1999).

6339:

Kulkarni H, Marconi VC, He W, Landrum ML, Okulicz JF, Delmar J, Kazandjian D, Castiblanco J, Ahuja SS, Wright EJ, Weiss RA, Clark RA, Dolan MJ, Ahuja SK (July 2009).

4876:

Keramati MR, Shakibaei H, Kheiyyami MI, Ayatollahi H, Badiei Z, Samavati M, Sadeghian MH (October 2011). "Blood group antigens frequencies in the northeast of Iran".

4403:

Ferri G, Bini C, Ceccardi S, Ingravallo F, Lugaresi F, Pelotti S (March 2006). "Minisequencing-based genotyping of Duffy and ABO blood groups for forensic purposes".

2696:

Yazdanbakhsh K, Rios M, Storry JR, Kosower N, Parasol N, Chaudhuri A, Reid ME (March 2000). "Molecular mechanisms that lead to reduced expression of duffy antigens".

1884:. This was first shown in 1980. Duffy negative individuals whose erythrocytes do not express the receptor are believed to be resistant to merozoite invasion although 1548:

Consequently, the Fy protein is also known as DARC (Duffy Antigen Receptor for Chemokines). The chemokine binding site on the receptor appears to be localised to the

9770: 8238: 3634:

Fukuma N, Akimitsu N, Hamamoto H, Kusuhara H, Sugiyama Y, Sekimizu K (2003). "A role of the Duffy antigen for the maintenance of plasma chemokine concentrations".

5127:

Wurtz N, Mint Lekweiry K, Bogreau H, Pradines B, Rogier C, Ould Mohamed Salem Boukhary A, Hafid JE, Ould Ahmedou Salem MS, Trape JF, Basco LK, Briolant S (2011).

7091:"Close association of the first and fourth extracellular domains of the Duffy antigen/receptor for chemokines by a disulfide bond is required for ligand binding" 1888:

infection has been reported in Duffy negative children in Kenya, suggesting a role in resistance to disease, not infection. This antigen may also play a role in

1575:

In DARC-transfected cells, DARC is internalized following ligand binding and this led to the hypothesis that expression of DARC on the surface of erythrocytes,

9815: 6764:

Watorek E, Boratyńska M, Hałoń A, Klinger M (2008). "Anti-Fya antibodies as the cause of an unfortunate post-transplant course in renal transplant recipient".

7056:"Genomic organization of the glycoprotein D gene: Duffy blood group Fya/Fyb alloantigen system is associated with a polymorphism at the 44-amino acid residue" 7377: 6537:"Duffy antigen receptor for chemokines and CXCL5 are essential for the recruitment of neutrophils in a multicellular model of rheumatoid arthritis synovium" 5673:

Kano FS, de Souza AM, de Menezes Torres L, Costa MA, Souza-Silva FA, Sanchez BA, Fontes CJ, Soares IS, de Brito CF, Carvalho LH, Sousa TN (September 2018).

2446:"Cloning of glycoprotein D cDNA, which encodes the major subunit of the Duffy blood group system and the receptor for the Plasmodium vivax malaria parasite" 4489:

Kobyliansky E, Micle S, Goldschmidt-Nathan M, Arensburg B, Nathan H (1980). "Duffy, Kell and P blood group systems in some Jewish populations of Israel".

3554:"The promiscuous chemokine binding profile of the Duffy antigen/receptor for chemokines is primarily localized to sequences in the amino-terminal domain" 1210:(Fy-a, Fy-b, Fy-o, Fy-x and Fy-y) and five antigens. Fy-x is a form of Fy-b where the Fy-b gene is poorly expressed. Fy-x is also known as Fy-b or Fy-b. 4294:

Miller LH, Mason SJ, Clyde DF, McGinniss MH (August 1976). "The resistance factor to Plasmodium vivax in blacks. The Duffy-blood-group genotype, FyFy".

1336:

The Duffy negative phenotype occurs at low frequency among whites (~3.5%) and is due to a third mutation that results in an unstable protein (Arg89Cys:

781: 136: 5508:

King CL, Adams JH, Xianli J, Grimberg BT, McHenry AM, Greenberg LJ, Siddiqui A, Howes RE, da Silva-Nunes M, Ferreira MU, Zimmerman PA (November 2011).

2016:

A study in Brazil confirmed the protective effect of FY*A/FY*O against malaria. In contrast the genotype FY*B/FY*O was associated with a greater risk.

762: 1741:

the frequency of the Fy allele is 0.5879. The frequency of this allele varies from 0.1083 to 0.2191 among Jews from the Middle East, North Africa and

7164:"A novel mutation in the coding sequence of the FY*B allele of the Duffy chemokine receptor gene is associated with an altered erythrocyte phenotype" 4749:

Sellami MH, Kaabi H, Midouni B, Dridi A, Mojaat N, Boukef MK, Hmida S (2008). "Duffy blood group system genotyping in an urban Tunisian population".

5078:"Duffy Negative Antigen Is No Longer a Barrier to Plasmodium vivax – Molecular Evidences from the African West Coast (Angola and Equatorial Guinea)" 3313:"The Duffy antigen/receptor for chemokines (DARC) is expressed in endothelial cells of Duffy negative individuals who lack the erythrocyte receptor" 1953:

offered by the lack of the Duffy antigen found no differential resistance to malaria vivax between Duffy antigen positive and negative individuals.

9657: 6292:"Duffy Antigen Receptor for Chemokines Mediates trans-Infection of HIV-1 from Red Blood Cells to Target Cells and Affects HIV-AIDS Susceptibility" 5675:"Susceptibility to Plasmodium vivax malaria associated with DARC (Duffy antigen) polymorphisms is influenced by the time of exposure to malaria" 9414: 8228: 7017:

Tournamille C, Le Van Kim C, Gane P, Cartron JP, Colin Y (1995). "Molecular basis and PCR-DNA typing of the Fya/fyb blood group polymorphism".

3164:

Horuk R, Martin AW, Wang Z, Schweitzer L, Gerassimides A, Guo H, Lu Z, Hesselgesser J, Perez HD, Kim J, Parker J, Hadley TJ, Peiper SC (1997).

1607:

The Duffy antigen has been shown to exist as a constitutive homo-oligomer and that it hetero-oligomerizes with the CC chemokine receptor CCR5 (

5076:

Mendes C, Dias F, Figueiredo J, Mora VG, Cano J, de Sousa B, do Rosário VE, Benito A, Berzosa P, Arez AP (June 2011). Franco-Paredes C (ed.).

7355: 7315: 5367:"Plasmodium vivax infection in Anajas, State of Para: no differential resistance profile among Duffy-negative and Duffy-positive individuals" 3671:"Duffy antigen facilitates movement of chemokine across the endothelium in vitro and promotes neutrophil transmigration in vitro and in vivo" 2840:

Zimmerman PA, Woolley I, Masinde GL, Miller SM, McNamara DT, Hazlett F, Mgone CS, Alpers MP, Genton B, Boatin BA, Kazura JW (November 1999).

2397: 2379: 1355:

A comparative study of this gene in seven mammalian species revealed significant differences between species. The species examined included

2899:

Awasthi G, Dashb AP, Dasa A (September 2009). "Evolutionary insights into duffy gene in mammalian taxa with comparative genetic analysis".

1992:

compared with Fyb cells. Individuals with the Fy(a+b-) phenotype have a 30-80% reduced risk of clinical vivax but not falciparum malaria.

9652: 6488:"Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers" 5957:"Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene" 9662: 9535: 8208: 2318: 1705:

Islands, part of India, were originally inhabited by 14 aboriginal tribes. Several of these have gone extinct. One surviving tribe—the

989: 2926:

Tung J, Primus A, Bouley AJ, Severson TF, Alberts SC, Wray GA (July 2009). "Evolution of a malaria resistance gene in wild primates".

996: 9070: 7394: 7370: 4172:

Pruenster M, Mudde L, Bombosi P, Dimitrova S, Zsak M, Middleton J, Richmond A, Graham GJ, Segerer S, Nibbs RJ, Rot A (January 2009).

3874:"The Duffy antigen receptor for chemokines is up-regulated during acute renal transplant rejection and crescentic glomerulonephritis" 5178:

Cavasini CE, de Mattos LC, Couto AA, Couto VS, Gollino Y, Moretti LJ, Bonini-Domingos CR, Rossit AR, Castilho L, Machado RL (2007).

3311:

Peiper SC, Wang ZX, Neote K, Martin AW, Showell HJ, Conklyn MJ, Ogborne K, Hadley TJ, Lu ZH, Hesselgesser J, Horuk R (April 1995).

3071:"One-step immunopurification and lectinochemical characterization of the Duffy atypical chemokine receptor from human erythrocytes" 2116:(a low total white cell count) is associated with relatively poor survival in HIV infection and this association is more marked in 1817: 4975:

Ryan JR, Stoute JA, Amon J, Dunton RF, Mtalib R, Koros J, Owour B, Luckhart S, Wirtz RA, Barnwell JW, Rosenberg R (October 2006).

1486:

The Duffy antigen has been found to act as a multispecific receptor for chemokines of both the C-C and C-X-C families, including:

8801: 3026:

Oliveira TY, Harris EE, Meyer D, Jue CK, Silva WA (2012). "Molecular evolution of a malaria resistance gene (DARC) in primates".

2596: 1215: 7307: 6199:"Enhanced expression of Duffy antigen receptor for chemokines by breast cancer cells attenuates growth and metastasis potential" 9678: 8789: 8567: 7329: 1945:. Additional cases of infection in Duffy antigen negative individuals have been reported from the Congo and Uganda. A study in 7199:"The Fy(x) phenotype is associated with a missense mutation in the Fy(b) allele predicting Arg89Cys in the Duffy glycoprotein" 4331:"The mutation G298A→Ala100Thr on the coding sequence of the Duffy antigen/chemokine receptor gene in non-caucasian Brazilians" 9647: 8853: 8848: 8794: 8574: 5567:

McMorran BJ, Wieczorski L, Drysdale KE, Chan JA, Huang HM, Smith C, Mitiku C, Beeson JG, Burgio G, Foote SJ (December 2012).

4234: 6674:

Lee JS, Frevert CW, Thorning DR, Segerer S, Alpers CE, Cartron JP, Colin Y, Wong VA, Martin TR, Goodman RB (February 2003).

2362: 2171:

An increased incidence of Duffy antigen has been reported in patients with multiple myeloma compared with healthy controls.

9945: 9940: 9673: 8307: 8233: 7363: 4255:"Determination of Duffy genotypes in three populations of African descent using PCR and sequence-specific oligonucleotides" 1432:

The gene appears to be under strong purifying selection. The cause of this selective pressure has not yet been identified.

47: 6107:"Neutrophil Effector Functions Are Not Impaired in Duffy Antigen Receptor for Chemokines (DARC)-Null Black South Africans" 2027:

is more common and tends to be more severe in those of African descent. There appears to be a correlation with both total

9336: 9331: 9326: 9321: 8248: 5265:

Culleton R, Ndounga M, Zeyrek FY, Coban C, Casimiro PN, Takeo S, Tsuboi T, Yadava A, Carter R, Tanabe K (November 2009).

2341: 5622:

Sampath S, Carrico C, Janes J, Gurumoorthy S, Gibson C, Melcher M, Chitnis CE, Wang R, Schief WR, Smith JD (June 2013).

9407: 5624:"Glycan Masking of Plasmodium vivax Duffy Binding Protein for Probing Protein Binding Function and Vaccine Development" 4360:

Bauduer F, Feingold J, Lacombe D (October 2005). "The Basques: review of population genetics and Mendelian disorders".

6872:"Southeast Asian ovalocytosis is associated with increased expression of Duffy antigen receptor for chemokines (DARC)" 2297:

subsequent alloimmunization. They display dosage (react more strongly to homozygous cells versus heterozygous cells).

1731:. Blood grouping revealed an absence of both Fy(a) and Fy(b) antigens in two areas and a low prevalence in two others. 9690: 9301: 6341:"The Duffy-null state is associated with a survival advantage in leukopenic HIV-infected persons of African ancestry" 3403:"Identification and characterization of a promiscuous chemokine-binding protein in a human erythroleukemic cell line" 2241: 1148: 5510:"Fya/Fyb antigen polymorphism in human erythrocyte Duffy antigen affects susceptibility to Plasmodium vivax malaria" 4913:"Natural Selection Mediated Association of the Duffy (FY) Gene Polymorphisms with Plasmodium vivax Malaria in India" 3493:

McMorran BJ, Wieczorski L, Drysdale KE, Chan JA, Huang HM, Smith C, Mitiku C, Beeson JG, Burgio G, Foote SJ (2012).

300: 8537: 6390:"Duffy-Null–Associated Low Neutrophil Counts Influence HIV-1 Susceptibility in High-Risk South African Black Women" 3669:

Lee JS, Frevert CW, Wurfel MM, Peiper SC, Wong VA, Ballman KK, Ruzinski JT, Rhim JS, Martin TR, Goodman RB (2003).

9105: 8599: 8285: 2366: 2345: 2307: 1917:. Although 72% of the population are Duffy antigen negative, 8.8% of the Duffy antigen negative individuals were 277: 5955:

Reich D, Nalls MA, Kao WH, Akylbekova EL, Tandon A, Patterson N, et al. (January 2009). Visscher PM (ed.).

5180:"Duffy blood group gene polymorphisms among malaria vivax patients in four areas of the Brazilian Amazon region" 1615:

and calcium flux through CCR5, whereas internalization of CCR5 in response to ligand binding remains unchanged.

9955: 8744: 8280: 3262:

Rot A, Gutjahr JC, Biswas A, Aslani M, Hub E, Thiriot A, von Andrian UH, Megens RT, Weber C, Duchene J (2022).

826: 7385: 2208:

Antibodies and a cellular response to the Duffy antigen have been associated with renal transplant rejection.

107:, atypical chemokine receptor 1 (Duffy blood group), CCBP1, CD234, Dfy, FY, GPD, GpFy, WBCQ1, DARC, DARC/ACKR1 9965: 9475: 9400: 9241: 8713: 8708: 8653: 8387: 7836: 6158:"The DARC side of metastasis: shining a light on KAI1-mediated metastasis suppression in the vascular tunnel" 3595:"Expression of the Duffy antigen in K562 cells. Evidence that it is the human erythrocyte chemokine receptor" 3362:"Expression of the Duffy antigen in K562 cells. Evidence that it is the human erythrocyte chemokine receptor" 1966:

infection. This species' erythrocytes possess the Duffy antigen and this antigen is used as the receptor for

1858:

protozoa has not been appreciated. Recent work has identified a number of additional roles for this protein.

5906:

Legge SE, Christensen RH, Petersen L, Pardiñas AF, Bracher-Smith M, Knapper S, et al. (December 2020).

5733:"Gene Encoding Duffy Antigen/Receptor for Chemokines Is Associated with Asthma and IgE in Three Populations" 807: 9725: 9579: 8935: 8658: 5843: 2230: 1562: 199: 174: 116: 4977:"Evidence for transmission of Plasmodium vivax among a duffy antigen negative population in Western Kenya" 4174:"The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity" 9595: 8253: 2549:"Strict tropism for CD71+/CD234+human reticulocytes limits the zoonotic potential ofPlasmodium cynomolgi" 2252: 1647:

people). This phenotype is exceedingly rare in Whites. Because the Duffy antigen is uncommon in those of

1202:. It carries the antigenic determinants of the Duffy blood group system which consist of four codominant 313: 212: 8965: 7390: 6535:

Smith E, McGettrick HM, Stone MA, Shaw JS, Middleton J, Nash GB, Buckley CD, Ed Rainger G (July 2008).

1974: 1553: 1420:) mutations in this gene have been associated with protection from infection with species of the genus 6437:

Voruganti VS, Laston S, Haack K, Mehta NR, Smith CW, Cole SA, Butte NF, Comuzzie AG (September 2012).

4330: 2744:"Detection of the signature of natural selection in humans: evidence from the Duffy blood group locus" 2321:

is typically mild but rarely may be serious. Almost always due to anti-Fy and rarely anti-Fyb or Fy3.

306: 205: 9805: 9800: 9765: 9745: 9700: 9642: 7831: 6627:"High ratio of Duffy (a+b+) phenotype in patients with multiple myeloma compared to healthy controls" 6238:

Mayr FB, Spiel AO, Leitner JM, Firbas C, Jilma-Stohlawetz P, Chang JY, Key NS, Jilma B (April 2009).

5267:"Evidence for the transmission of Plasmodium vivax in the Republic of the Congo, West Central Africa" 2246: 2047:

present in the bone marrow have high expression of DARC, which facilitates their direct contact with

2044: 1981:

infection and FY*B/FY*X and FY*A/FY*X were shown to be associated with the low levels of parasitism.

3928: 103: 9622: 9612: 9015: 7910: 7301: 6290:

He W, Neil S, Kulkarni H, Wright E, Agan BK, Marconi VC, Dolan MJ, Weiss RA, Ahuja SK (July 2008).

5308:"Transmission of Plasmodium vivax in south-western Uganda: report of three cases in pregnant women" 2048: 1706: 947: 900: 124: 4044:

Segerer S, Böhmig GA, Exner M, Colin Y, Cartron JP, Kerjaschki D, Schlöndorff D, Regele H (2003).

1093:, and is named after the patient in whom it was discovered. The protein encoded by this gene is a 9919: 9870: 9850: 9497: 8979: 7297: 5365:

Carvalho TA, Queiroz MG, Cardoso GL, Diniz IG, Silva AN, Pinto AY, Guerreiro JF (December 2012).

3264:"Murine bone marrow macrophages and human monocytes do not express atypical chemokine receptor 1" 1867: 1291: 1187: 1101: 972: 951: 921: 896: 9950: 9894: 9840: 9735: 9713: 9460: 8322: 8317: 8312: 8302: 7609: 7537: 7072: 7055: 3923: 1127: 7324: 6717:"The Duffy Antigen/Receptor for Chemokines (DARC) and Prostate-Cancer Risk among Jamaican Men" 4561:"ABO, Rh, MNS, Duffy, Kidd, Yt, Scianna, and Colton blood group systems in indigenous Chinese" 3872:

Segerer S, Regele H, MacK M, Kain R, Cartron JP, Colin Y, Kerjaschki D, Schlöndorff D (2000).

9880: 9835: 9740: 9392: 7666: 7584: 6055:

Legge SE, Pardiñas AF, Helthuis M, Jansen JA, Jollie K, Knapper S, et al. (March 2019).

2001: 1793: 1723: 1556:

shows that DARC lacks the highly conserved DRY motif in the second intracellular loop of the

1502:

melanoma growth stimulatory activity (MSGA-α), KC, neutrophil-activating protein 3 (NAP-3) -

1387: 1255: 7197:

Olsson ML, Smythe JS, Hansson C, Poole J, Mallinson G, Jones J, Avent ND, Daniels G (1999).

7089:

Tournamille C, Le Van Kim C, Gane P, Blanchard D, Proudfoot AE, Cartron JP, Colin Y (1997).

6056: 5569:"Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum" 1913:

malaria conferred by the absence of the Duffy antigen appears to be very limited at best in

9845: 9750: 9632: 9574: 9453: 9427: 8616: 6715:

Elson JK, Beebe-Dimmer JL, Morgenstern H, Chilkuri M, Blanchard J, Lentsch AB (July 2010).

6008:"Absolute neutrophil count by Duffy status among healthy Black and African American adults" 5859:"Absolute neutrophil count by Duffy status among healthy Black and African American adults" 5686: 5580: 5521: 5319: 5030: 4924: 4832: 3510: 3459: 3442:

Horuk R, Chitnis CE, Darbonne WC, Colby TJ, Rybicki A, Hadley TJ, Miller LH (August 1993).

2935: 2853: 2619: 2457: 1918: 1326: 1122: 188: 144: 6950:

Pogo AO, Chaudhuri A (1996). "Duffy and receptors for P. vivax and chemotactic peptides".

5019:"Plasmodium vivax clinical malaria is commonly observed in Duffy-negative Malagasy people" 4714:

Mathews HM, Armstrong JC (March 1981). "Duffy blood types and vivax malaria in Ethiopia".

2080:

on tumor cells and the cytokine receptor DARC on adjacent vascular cells suppresses tumor

1760:—the frequencies of Fya and Fyb alleles were 0.94 and 0.06 and 0.98 and 0.02 respectively. 8: 9830: 9820: 9470: 8930: 8749: 5418:"Plasmodium vivax DBP binding to Aotus nancymaae erythrocytes is Duffy antigen dependent" 2217: 1880: 1623: 1140: 1116: 6486:

Sidore C, Busonero F, Maschio A, Porcu E, Naitza S, Zoledziewska M, et al. (2015).

5690: 5584: 5525: 5323: 5034: 4928: 4836: 3514: 3463: 3134: 2939: 2857: 2709: 2623: 2461: 2245:

Interpretation of antibody panel to detect patient antibodies towards the most relevant

1206:—FY*A and FY*B—coding for the Fy-a and Fy-b antigens respectively, FY*X and FY*Fy, five 9860: 8337: 8071: 7228: 7150: 7042: 7005: 6888: 6871: 6816: 6741: 6716: 6656: 6561: 6536: 6512: 6487: 6463: 6438: 6414: 6389: 6365: 6340: 6316: 6291: 6269: 6133: 6106: 6087: 6032: 6007: 5983: 5956: 5932: 5907: 5883: 5858: 5814: 5789: 5757: 5732: 5707: 5674: 5650: 5623: 5604: 5544: 5509: 5490: 5442: 5417: 5393: 5366: 5342: 5307: 5206: 5179: 5155: 5128: 5104: 5077: 5053: 5018: 4947: 4912: 4853: 4820: 4774: 4626: 4577: 4560: 4541: 4471: 4428: 4385: 4223: 4198: 4173: 4154: 4075: 4026: 3778: 3695: 3670: 3534: 3337: 3312: 3293: 3195: 3166:"Expression of chemokine receptors by subsets of neurons in the central nervous system" 3146: 3095: 3070: 3051: 3003: 2978: 2959: 2768: 2743: 2721: 2678: 2635: 2573: 2548: 2528: 1593:

migration from the blood into the tissues and in modulating the inflammatory response.

1568: 1416: 1318: 1247: 148: 7253: 6963: 4271: 4254: 4062: 4045: 3937: 3647: 3611: 3594: 3419: 3402: 3378: 3361: 3239: 3214: 3213:

Hadley TJ, Lu ZH, Wasniowska K, Martin AW, Peiper SC, Hesselgesser J, Horuk R (1994).

2817: 2792: 696: 691: 686: 681: 676: 671: 655: 650: 645: 640: 635: 630: 614: 609: 604: 594: 589: 584: 9960: 9914: 9909: 9795: 9492: 9423: 7344: 7335: 7278: 7257: 7220: 7215: 7198: 7185: 7142: 7112: 7077: 7034: 6997: 6967: 6893: 6852: 6808: 6804: 6773: 6746: 6697: 6648: 6607: 6566: 6517: 6468: 6419: 6370: 6321: 6261: 6256: 6239: 6220: 6179: 6138: 6079: 6037: 6023: 5988: 5937: 5888: 5874: 5819: 5762: 5712: 5655: 5608: 5596: 5549: 5482: 5447: 5398: 5347: 5288: 5247: 5211: 5160: 5109: 5058: 4998: 4952: 4893: 4858: 4801: 4766: 4731: 4696: 4661: 4618: 4582: 4533: 4498: 4463: 4459: 4420: 4416: 4377: 4342: 4311: 4276: 4230: 4203: 4146: 4110: 4067: 4018: 3982: 3941: 3895: 3890: 3873: 3854: 3819: 3814: 3797: 3770: 3735: 3700: 3651: 3616: 3593:

Chaudhuri A, Zbrzezna V, Polyakova J, Pogo AO, Hesselgesser J, Horuk R (March 1994).

3575: 3538: 3526: 3475: 3424: 3383: 3342: 3297: 3285: 3244: 3187: 3138: 3100: 3043: 3008: 2994: 2951: 2908: 2881: 2876: 2841: 2822: 2773: 2713: 2670: 2578: 2520: 2485: 2480: 2445: 2444:

Chaudhuri A, Polyakova J, Zbrzezna V, Williams K, Gulati S, Pogo AO (November 1993).

1930: 1894: 1652: 1375: 96: 40: 7154: 7046: 6820: 6660: 6273: 6091: 5790:"Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis" 5494: 4778: 4630: 4545: 4475: 4389: 4158: 4079: 4030: 3199: 3150: 3055: 2725: 2310:, but only rarely. Anti-Fy5 may also cause delayed hemolytic transfusion reactions. 1694:

as a genetically separate group. Its use in forensic science is under consideration.

128: 9617: 9564: 9530: 9504: 9110: 8843: 8764: 8327: 7520: 7446: 7249: 7232: 7210: 7175: 7134: 7102: 7067: 7026: 7009: 6989: 6959: 6883: 6844: 6800: 6736: 6728: 6687: 6638: 6597: 6556: 6548: 6507: 6499: 6458: 6450: 6409: 6401: 6360: 6352: 6311: 6303: 6251: 6210: 6169: 6128: 6118: 6071: 6027: 6019: 6006:

Merz LE, Story CM, Osei MA, Jolley K, Ren S, Park HS, et al. (February 2023).

5978: 5968: 5927: 5919: 5878: 5870: 5857:

Merz LE, Story CM, Osei MA, Jolley K, Ren S, Park HS, et al. (February 2023).

5809: 5801: 5752: 5744: 5702: 5694: 5645: 5635: 5588: 5539: 5529: 5474: 5437: 5429: 5388: 5378: 5337: 5327: 5278: 5239: 5201: 5191: 5150: 5140: 5099: 5089: 5048: 5038: 4988: 4942: 4932: 4885: 4848: 4840: 4758: 4723: 4688: 4653: 4610: 4572: 4525: 4455: 4432: 4412: 4369: 4303: 4266: 4193: 4185: 4138: 4102: 4057: 4010: 3972: 3933: 3885: 3846: 3809: 3798:"Up-regulation of Duffy antigen receptor expression in children with renal disease" 3782: 3762: 3727: 3690: 3682: 3643: 3606: 3565: 3518: 3467: 3414: 3373: 3332: 3324: 3275: 3234: 3226: 3177: 3130: 3090: 3082: 3035: 2998: 2990: 2963: 2943: 2871: 2861: 2812: 2804: 2763: 2755: 2705: 2682: 2662: 2639: 2627: 2568: 2560: 2532: 2512: 2475: 2465: 2148: 2112:

The association between the Duffy antigen and HIV infection appears to be complex.

1988:

malaria has been reported. Erythrocytes expressing Fya had 41-50% lower binding of

1640: 1429:

The ancestral form of extant DARC alleles in humans appears to be the FY*B allele.

1399: 1349: 1110: 1097: 393: 324: 268: 223: 4889: 4657: 3977: 3960: 3850: 1854:

Historically the role of this antigen other than its importance as a receptor for

1448:

than on mature erythrocytes. While the Duffy antigen is expressed on bone marrow

1411:

the mouse DARC is expressed during embryonic development between days 9.5 and 12.

9904: 9718: 9485: 9480: 9170: 7706: 7701: 7624: 6625:

Guler N, Turgut M, Ozatli D, Turgut Y, Gokce AK, Koc S, Albayrak D (March 2009).

6356: 5973: 5640: 5332: 5243: 5094: 4937: 3686: 2564: 1958: 1742: 1702: 1698: 1357: 368: 152: 6676:"Enhanced expression of Duffy antigen in the lungs during suppurative pneumonia" 4307: 3182: 3165: 2842:"Emergence of FY*Anull in a Plasmodium vivax-endemic region of Papua New Guinea" 2610:

Cutbush M, Mollison PL, Parkin DM (4 February 1950). "A New Human Blood Group".

2402:

National Center for Biotechnology Information, U.S. National Library of Medicine

2384:

National Center for Biotechnology Information, U.S. National Library of Medicine

9790: 9685: 9600: 9560: 9525: 8955: 8377: 7888: 7691: 6848: 6692: 6675: 6454: 6307: 5698: 5129:"Vivax malaria in Mauritania includes infection of a Duffy-negative individual" 3360:

Chaudhuri A, Zbrzezna V, Polyakova J, Pogo AO, Hesselgesser J, Horuk R (1994).

3280: 3263: 1821: 1785: 1749: 1714: 1457: 1369: 1363: 1329:. The gene is still transcribed in non erythroid cells in the presence of this 1243: 1090: 469: 6732: 6602: 6585: 6174: 6157: 6075: 5748: 5478: 4993: 4976: 4762: 4727: 4679:

Rosenberg R (May 2007). "Plasmodium vivax in Africa: hidden in plain sight?".

3552:

Lu ZH, Wang ZX, Horuk R, Hesselgesser J, Lou YC, Hadley TJ, Peiper SC (1995).

3086: 3039: 9934: 9775: 9568: 9435: 8925: 8382: 7473: 7180: 7163: 7138: 7107: 7090: 6240:"Racial differences in endotoxin-induced tissue factor-triggered coagulation" 6123: 5383: 5145: 4692: 3731: 3570: 3553: 2866: 2470: 2288:

Almost entirely IgG. IgG1 usually predominates. IgM does occur but is rare.

2040: 1767: 1710: 1691: 1585: 1542: 1449: 1231: 571: 5592: 5534: 5196: 5043: 3522: 3471: 1941:

has also been reported. Similar infections have been reported in Brazil and

1690:

This antigen along with other blood group antigens was used to identify the

1682:

position—base number 298) within the FY*B allele was thought to be purely a

599: 529: 407: 9824: 9465: 9281: 8589: 8579: 8110: 8076: 7282: 6978: 6897: 6856: 6812: 6777: 6750: 6701: 6652: 6611: 6570: 6521: 6472: 6423: 6374: 6325: 6265: 6224: 6215: 6198: 6183: 6142: 6083: 6041: 5992: 5941: 5892: 5823: 5786: 5766: 5716: 5659: 5600: 5553: 5486: 5451: 5402: 5351: 5292: 5251: 5215: 5164: 5113: 5062: 5002: 4956: 4897: 4862: 4770: 4700: 4665: 4622: 4586: 4537: 4488: 4467: 4424: 4381: 4346: 4280: 4207: 4150: 4142: 4114: 4071: 4022: 3986: 3945: 3899: 3858: 3823: 3774: 3739: 3704: 3655: 3530: 3328: 3289: 3142: 3104: 3047: 3012: 2955: 2912: 2885: 2826: 2777: 2717: 2582: 2121: 2117: 1825: 1753: 1648: 1453: 1445: 1422: 1381: 1306: 1199: 1191: 1167: 1094: 386: 165: 7261: 7224: 7189: 7146: 7116: 7081: 7038: 7001: 6971: 6105:

Naidoo KK, Ngubane A, Gaza P, Moodley A, Ndung'u T, Thobakgale CF (2019).

5923: 4805: 4735: 4614: 4529: 4502: 4373: 3620: 3579: 3479: 3428: 3387: 3346: 3248: 3191: 2674: 2524: 2489: 1036: 1031: 9780: 9607: 9443: 9291: 8940: 8718: 8693: 8392: 8014: 7940: 7414: 6405: 6197:

Wang J, Ou ZL, Hou YF, Luo JM, Shen ZZ, Ding J, Shao ZM (November 2006).

4315: 2163:

The Duffy antigen has been implicated in lung transplantation rejection.

2077: 1889: 1816:

are Duffy antigen positive, while only 2% of black ethnic groups (mainly

1789: 1777:

The incidence of Fy(a+b-) in northern India among blood donors is 43.85%.

1644: 1636: 1576: 1468: 1162:

named Richard Duffy, whose serum contained the first example of anti-Fya

1159: 1144: 871: 852: 3959:

Brühl H, Vielhauer V, Weiss M, Mack M, Schlöndorff D, Segerer S (2005).

2947: 2793:"Complex Signatures of Natural Selection at the Duffy Blood Group Locus" 2187:

Duffy antigen has been implicated in haemolytic disease of the newborn.

1178:

distinct, unrelated antigen and is no longer included in the FY system.

9708: 9520: 9221: 8945: 8626: 8367: 8243: 7876: 7871: 7866: 7721: 7505: 7030: 6993: 5306:

Dhorda M, Nyehangane D, Rénia L, Piola P, Guerin PJ, Snounou G (2011).

4844: 4106: 2666: 2516: 2113: 2081: 2060: 1938: 1914: 1855: 1809: 1805: 1757: 1683: 1612: 1590: 1580: 1549: 1480: 1461: 1393: 1314: 1223: 1171: 285: 182: 132: 6552: 5464: 5433: 4014: 3766: 3495:"Platelet factor 4 and Duffy antigen required for platelet killing of 3230: 73: 69: 9785: 9667: 9556: 9060: 9055: 9050: 9040: 9035: 9030: 9025: 4329:

Estalote AC, Proto-Siqueira R, Silva WA, Zago MA, Palatnik M (2005).

4225:

Medical microbiology & immunology: examination & board review

3837:

Rot A (2005). "Contribution of Duffy antigen to chemokine function".

2631: 2415: 1621:

Binding melanoma growth-stimulating activity inhibits the binding of

1601: 1496:

regulated upon activation normal T expressed and secreted (RANTES) -

1341: 1287: 1279: 1263: 1239: 1207: 1105: 726: 352: 339: 251: 238: 140: 7239: 7162:

Parasol N, Reid M, Rios M, Castilho L, Harari I, Kosower NS (1998).

6714: 6643: 6626: 6503: 5805: 4875: 4189: 3443: 3069:

Grodecka M, Bertrand O, Karolak E, Lisowski M, Waśniowska K (2012).

1166:. In 1951, the antibody to a second antigen, Fyb, was discovered in 1108:. The protein is also the receptor for the human malarial parasites 9540: 9448: 9366: 9266: 9080: 9065: 8268: 8263: 8171: 7861: 6586:"The role of chemokine receptors in acute lung allograft rejection" 5568: 5283: 5266: 5015: 3494: 2808: 2759: 2125: 2059:

Individuals with the Duffy-null genotype have a persistently lower

1771: 1337: 1330: 1271: 1267: 1259: 1163: 1020: 7123: 7088: 5672: 5228: 3752: 2443: 1763:

The frequency of the Fya allele in most Asian populations is ~95%.

9899: 9865: 9316: 9311: 9306: 9206: 9020: 9010: 8837: 8816: 8811: 8779: 8584: 8504: 8499: 8494: 8489: 8484: 8402: 8095: 7935: 7930: 7925: 7920: 7915: 7386: 7349: 7339: 6870:

Woolley IJ, Hutchinson P, Reeder JC, Kazura JW, Cortés A (2020).

5126: 4599: 2502: 2197: 1899: 1871: 1781: 1718: 1557: 1465: 1321:

activity in erythroid cells by disrupting a binding site for the

1295: 1283: 1275: 1235: 1227: 1155: 1076: 838: 793: 711: 707: 7016: 6833: 5905: 3120: 120: 9810: 9256: 9216: 9201: 9185: 9180: 9160: 9155: 9090: 8898: 8868: 8832: 8823: 8636: 8604: 8468: 8463: 8433: 8412: 8372: 8332: 8198: 8176: 8135: 8059: 8054: 8049: 8044: 8039: 8034: 7903: 7898: 7893: 7841: 7826: 7696: 7686: 7649: 7644: 7562: 7557: 4328: 3068: 2024: 1946: 1926: 1846:

The distribution within India has been studied in some detail.

1472: 1310: 1299: 1203: 1004: 748: 9422: 6583: 5621: 5566: 4171: 3633: 3592: 3492: 3359: 2268:

International Society for Blood Transfusion (ISBT) symbol: FY

1651:

descent, the presence of this antigen has been used to detect

9889: 9875: 9855: 9381: 9356: 9276: 9271: 9261: 9251: 9236: 9231: 9226: 9211: 9165: 9150: 9115: 9100: 9095: 9085: 9005: 9000: 8995: 8974: 8970: 8960: 8873: 8774: 8769: 8728: 8678: 8673: 8668: 8663: 8648: 8641: 8621: 8609: 8552: 8547: 8542: 8532: 8527: 8520: 8458: 8448: 8443: 8438: 8428: 8407: 8397: 8362: 8357: 8352: 8347: 8342: 8297: 8292: 8258: 8223: 8218: 8213: 8203: 8191: 8186: 8166: 8161: 8156: 8151: 8105: 7997: 7992: 7811: 7795: 7788: 7783: 7778: 7773: 7768: 7763: 7738: 7716: 7711: 7604: 7530: 7525: 7515: 7311: 6869: 6790: 6763: 4252: 2839: 2695: 2652: 2313: 2109:

HIV-1 appears to be able to attach to erythrocytes via DARC.

1999:) appears to be critical for the platelet induced killing of 1996: 1942: 1813: 1797: 1735: 1679: 1608: 1596:

The protein is also known to interact with the protein KAI1 (

1536: 1530: 1524: 1518: 1507: 1503: 1322: 1251: 7334:

Overview of all the structural information available in the

3961:"Expression of DARC, CXCR3 and CCR5 in giant cell arteritis" 2545: 1130:

in this gene are the basis of the Duffy blood group system.

9884: 9755: 9730: 9376: 9371: 9361: 9351: 9346: 9341: 9296: 9286: 9246: 9175: 9145: 9140: 9135: 9130: 9125: 9120: 9075: 9045: 8950: 8918: 8913: 8893: 8883: 8878: 8863: 8858: 8759: 8754: 8723: 8703: 8698: 8688: 8683: 8562: 8515: 8475: 8130: 8125: 8120: 8115: 8100: 8091: 8086: 8081: 8066: 8024: 8019: 8009: 8004: 7987: 7982: 7977: 7972: 7967: 7962: 7957: 7952: 7947: 7883: 7856: 7851: 7846: 7821: 7816: 7753: 7748: 7743: 7733: 7728: 7681: 7676: 7671: 7661: 7656: 7639: 7634: 7629: 7619: 7614: 7599: 7594: 7589: 7579: 7574: 7569: 7552: 7547: 7542: 7493: 7461: 7456: 7451: 7434: 7429: 7424: 7419: 7268: 6054: 5364: 5177: 4515: 4402: 3999: 3400: 2976: 2141: 1835: 1597: 1497: 1491: 1195: 1083: 6915: 6584:

Geleff S, Draganovici D, Jaksch P, Segerer S (July 2009).

6485: 5305: 5264: 4910: 4643: 3912: 1643:

and 88-100% in African people (including more than 90% of

8888: 7500: 7488: 7483: 7478: 7468: 7441: 7409: 7319: 6673: 6436: 6387: 4293: 3441: 3163: 2420:

U.S. National Library of Medicine Genetics Home Reference

2102: 2028: 1812:

overall 27% of the population are Duffy-positive. 54% of

1738: 7196: 6534: 6338: 6104: 5075: 4748: 3212: 2979:"DARC alleles and Duffy phenotypes in African Americans" 2925: 2790: 1444:

The Duffy antigen is expressed in greater quantities on

376: 7161: 6624: 5954: 5729: 5507: 4043: 3958: 3717: 3551: 7053: 6237: 4818: 4791: 4359: 4127: 3668: 3261: 3025: 2791:

Hamblin MT, Thompson EE, Di Rienzo A (February 2002).

2031:

levels and asthma and mutations in the Duffy antigen.

1302:) - that has been associated with the Fy-x phenotype. 4716:

The American Journal of Tropical Medicine and Hygiene

4093:

Pruenster M, Rot A (2006). "Throwing light on DARC".

3871: 3310: 2977:

Schmid P, Ravenell KR, Sheldon SL, Flegel WA (2011).

2609: 1479:

It has two potential N-linked glycosylation sites at

541: 6289: 5415: 4974: 4445: 3401:

Horuk R, Wang ZX, Peiper SC, Hesselgesser J (1994).

6005: 5856: 3796:Liu XH, Hadley TJ, Xu L, Peiper SC, Ray PE (1999). 1774:) the frequency of the Fy(a- b-) phenotype is 0.86. 6916:Roback J, Combs MR, Grossman B, Hillyer C (2008). 5416:McHenry AM, Barnwell JW, Adams JH (October 2009). 4911:Chittoria A, Mohanty S, Jaiswal YK, Das A (2012). 4821:"The global distribution of the Duffy blood group" 4222: 2358: 2356: 2354: 2337: 2335: 2333: 2196:of DARC to this increased risk has been tested in 1937:malaria in a Duffy antigen negative individual in 1190:gene (gp-Fy; CD234) is located on the long arm of 6933:Mollison's Blood Transfusion in Clinical Medicine 6784: 4214: 4001:Willebrand factor, CD31, CD34, CD105 and CD146". 3795: 323: 222: 9932: 9658:Transfusion-associated graft versus host disease 4713: 2898: 2741: 1973:Examination of this gene in 497 patients in the 1666:Fy(a-b+): 34% Whites, 22% Blacks, <1% Chinese 1294:) in this gene has also been described - G145T ( 1174:were defined: Fy(a+b+), Fy(a+b-), and Fy(a-b+). 6911: 6909: 6907: 6285: 6283: 6155: 5908:"The Duffy-null genotype and risk of infection" 4248: 4246: 3116: 3114: 2737: 2735: 2351: 2330: 2224: 2076:Interactions between the metastasis suppressor 1678:The mutation Ala100Thr (G -> A in the first 1089:The Duffy antigen is located on the surface of 7314:Blood Group Antigen Gene Mutation Database at 6935:(11th ed.). Oxford: Blackwell Publishing. 6430: 5782: 5780: 5778: 5776: 5222: 5171: 4792:Lepers JP, Simonneau M, Charmot G (1986). "". 2363:GRCm38: Ensembl release 89: ENSMUSG00000037872 1604:and may have a role in the control of cancer. 9408: 7371: 7054:Iwamoto S, Omi T, Kajii E, Ikemoto S (1995). 6949: 6708: 6381: 5560: 5358: 4229:. New York: Lange Medical Books/McGraw-Hill. 4165: 4086: 3993: 3746: 3586: 3062: 3019: 2439: 2437: 2229:There is a ~10% increase in Fy expression in 1866:On erythrocytes, the Duffy antigen acts as a 1611:). The formation of this heterodimer impairs 1250:(a T -> C mutation at position -33 in the 6904: 6863: 6757: 6479: 6332: 6280: 6231: 6196: 6190: 6149: 5837: 5835: 5833: 5723: 5666: 5615: 5458: 5409: 5299: 5258: 4970: 4968: 4966: 4904: 4869: 4742: 4593: 4552: 4439: 4396: 4353: 4322: 4243: 4092: 3486: 3353: 3111: 2919: 2892: 2833: 2784: 2732: 2689: 2054: 1669:Fy(a+b-): 17% Whites, 9% Blacks, 91% Chinese 682:G protein-coupled receptor signaling pathway 9653:Transfusion associated circulatory overload 6930: 5773: 4785: 4637: 4509: 4482: 4121: 4037: 3906: 3865: 2539: 2342:GRCh38: Ensembl release 89: ENSG00000213088 1984:A difference between the susceptibility to 1727:: there is no evidence for the presence of 1663:Fy(a+b+): 49% Whites, 1% Blacks, 9% Chinese 1198:. The gene encodes a 336 amino acid acidic 1170:. Using these two antibodies, three common 9663:Febrile non-hemolytic transfusion reaction 9536:International Society of Blood Transfusion 9415: 9401: 7378: 7364: 7073:10.1182/blood.V85.3.622.bloodjournal853622 6827: 6667: 6577: 5069: 5009: 4812: 4558: 4287: 3711: 3627: 3304: 3206: 2970: 2589: 2496: 2434: 2319:Hemolytic disease of the fetus and newborn 2314:Hemolytic disease of the fetus and newborn 2039:Duffy antigen plays a fundamental role on 1838:the Fy (a-b-) phenotype was found in 3.4%. 1535:Neutrophil activating peptide-2 (NAP-2) - 7395:list of human clusters of differentiation 7300:at the U.S. National Library of Medicine 7214: 7179: 7106: 7071: 6887: 6740: 6691: 6642: 6618: 6601: 6560: 6511: 6462: 6413: 6364: 6315: 6255: 6214: 6173: 6156:Zijlstra A, Quigley JP (September 2006). 6132: 6122: 6031: 5982: 5972: 5948: 5931: 5899: 5882: 5830: 5813: 5756: 5706: 5649: 5639: 5543: 5533: 5441: 5392: 5382: 5341: 5331: 5282: 5205: 5195: 5154: 5144: 5120: 5103: 5093: 5052: 5042: 4992: 4963: 4946: 4936: 4852: 4678: 4576: 4270: 4197: 4061: 3976: 3952: 3927: 3889: 3813: 3694: 3662: 3610: 3569: 3435: 3418: 3394: 3377: 3336: 3279: 3238: 3181: 3157: 3094: 3002: 2875: 2865: 2816: 2767: 2572: 2479: 2469: 2128:binding but this has yet to be verified. 1892:invasion in the rodent malarial parasite 1490:monocyte chemotactic protein-1 (MCP-1) - 595:transmembrane signaling receptor activity 5999: 5501: 4220: 2300: 2240: 2216:Duffy antigen-negative individuals with 1849: 1181: 1158:was discovered in a multiply-transfused 7348:(Atypical chemokine receptor 1) at the 3830: 3789: 3255: 2236: 2158: 9933: 6920:(16th ed.). Bethesda: AABB Press. 5844:"How Ancestry Shapes Our Immune Cells" 3545: 3444:"A receptor for the malarial parasite 2211: 2203: 1630: 9648:Transfusion related acute lung injury 9396: 7359: 3448:: the erythrocyte chemokine receptor" 2408: 2087: 2008:The Duffy antigen binding protein in 1970:on the erythrocytes in this species. 1313:with a single T to C substitution at 328: 289: 284: 227: 186: 181: 2742:Hamblin MT, Di Rienzo A (May 2000). 2291: 2101:A connection has been found between 1517:Growth related gene alpha (GRO-α) - 1435: 1222:Fy-a and Fy-b differ by in a single 672:chemokine-mediated signaling pathway 3836: 3135:10.1046/j.1537-2995.2000.40080949.x 2710:10.1046/j.1537-2995.2000.40030310.x 2263: 2166: 1513:and the angiogenic CXC chemokines: 1476:expressed in the other cell types. 590:G protein-coupled receptor activity 13: 6952:Transfusion Clinique et Biologique 6942: 6889:10.21307/immunohematology-2019-233 4578:10.21307/immunohematology-2019-386 2797:American Journal of Human Genetics 2748:American Journal of Human Genetics 2190: 2142:monocyte chemoattractant protein-1 1995:The binding of platelet factor 4 ( 677:regulation of chemokine production 14: 9977: 9691:Transfusion transmitted infection 7291: 5841: 4559:Yan L, Zhu F, Fu Q, He J (2020). 4063:10.1097/01.TP.0000054679.91112.6F 4046:"When renal allografts turn DARC" 1925:. Malaria has also been found in 1149:glucose-6-phosphate dehydrogenase 1079:that in humans is encoded by the 7216:10.1046/j.1365-2141.1998.01083.x 6924: 6805:10.1111/j.1537-2995.2007.01622.x 6257:10.1111/j.1538-7836.2009.03307.x 6024:10.1182/bloodadvances.2022007679 5875:10.1182/bloodadvances.2022007679 4460:10.1111/j.1365-3148.2005.00583.x 4417:10.1111/j.1556-4029.2006.00058.x 3891:10.1046/j.1523-1755.2000.00316.x 3815:10.1046/j.1523-1755.1999.00385.x 2995:10.1111/j.1537-2995.2011.03431.x 2283: 2096: 2034: 1962:) is used as an animal model of 1213:This gene has been redesignated 1049:Duffy antigen/chemokine receptor 312: 305: 299: 276: 211: 204: 198: 173: 16:Human blood group classification 6528: 6098: 6048: 5850: 4707: 4672: 2646: 2603: 2308:hemolytic transfusion reactions 2140:An association with the levels 2135: 2122:people of Black African descent 1933:in Duffy negative individuals. 1709:—live in three jungle areas of 2390: 2372: 631:integral component of membrane 530:More reference expression data 442:olfactory zone of nasal mucosa 1: 7254:10.1016/S0753-3322(99)80021-3 6964:10.1016/s1246-7820(05)80093-x 5737:Am. J. Respir. Crit. Care Med 5232:Trans. R. Soc. Trop. Med. Hyg 4890:10.1016/j.transci.2011.07.006 4794:Bull Soc Pathol Exot Filiales 4658:10.1016/j.transci.2010.05.006 4272:10.1016/S0198-8859(99)00039-7 3938:10.1016/S0272-6386(01)80009-3 3851:10.1016/j.cytogfr.2005.05.011 3648:10.1016/S0006-291X(03)00293-6 3636:Biochem. Biophys. Res. Commun 3612:10.1016/S0021-9258(17)37123-5 3420:10.1016/S0021-9258(17)32501-2 3379:10.1016/S0021-9258(17)37123-5 2324: 2277:Gene name: Duffy blood group 1120:and simian malarial parasite 297: 196: 9580:Intraoperative blood salvage 6931:Klein HG, Anstee DJ (2005). 6357:10.1182/blood-2009-04-215186 5974:10.1371/journal.pgen.1000360 5641:10.1371/journal.ppat.1003420 5333:10.1371/journal.pone.0019801 5244:10.1016/j.trstmh.2007.04.011 5095:10.1371/journal.pntd.0001192 5023:Proc. Natl. Acad. Sci. U.S.A 4938:10.1371/journal.pone.0045219 3687:10.4049/jimmunol.170.10.5244 2846:Proc. Natl. Acad. Sci. U.S.A 2597:"Entrez Gene: Duffy antigen" 2565:10.1182/blood-2017-02-764787 2450:Proc. Natl. Acad. Sci. U.S.A 2280:Number of Duffy antigens: 6 2231:Southeast Asian ovalocytosis 2225:Southeast Asian ovalocytosis 2182: 2174: 1600:) a surface glycoprotein of 1186:The Duffy antigen/chemokine 7: 9946:Clusters of differentiation 9941:Genes on human chromosome 1 9596:Blood compatibility testing 7391:clusters of differentiation 4308:10.1056/NEJM197608052950602 3978:10.1093/rheumatology/keh485 3183:10.4049/jimmunol.158.6.2882 2253:Blood compatibility testing 1721:. The causative species is 1639:phenotype Fy(a-b-): 68% in 1554:G-protein-coupled receptors 615:signaling receptor activity 430:subcutaneous adipose tissue 10: 9982: 6849:10.1016/j.clim.2010.02.023 6693:10.1177/002215540305100204 6455:10.1016/j.cyto.2012.08.029 6308:10.1016/j.chom.2008.06.002 5699:10.1038/s41598-018-32254-z 3839:Cytokine Growth Factor Rev 3281:10.1016/j.stem.2021.11.010 2250: 1949:of the protection against 1870:for invasion by the human 1861: 1717:. The area is endemic for 1352:has also been documented. 1246:in the erythroid specific 1133: 1075:ifferentiation 234), is a 600:signal transducer activity 9699: 9643:Transfusion hemosiderosis 9631: 9588: 9549: 9513: 9434: 9194: 8988: 8737: 8421: 8144: 7804: 7402: 6733:10.1007/s10903-010-9330-z 6603:10.1183/09031936.00042309 6175:10.1016/j.ccr.2006.08.012 6076:10.1038/s41380-018-0335-7 5749:10.1164/rccm.200801-182OC 5479:10.1007/s00436-010-1745-x 4994:10.4269/ajtmh.2006.75.575 4763:10.1080/03014460802082127 4728:10.4269/ajtmh.1981.30.299 3087:10.1007/s10719-011-9367-9 3040:10.1007/s00251-012-0608-2 2398:"Mouse PubMed Reference:" 2380:"Human PubMed Reference:" 2247:human blood group systems 2071: 2055:Benign ethnic neutropenia 2045:nucleated red blood cells 2019: 1956:Nancy Ma's night monkey ( 1035: 1030: 1026: 1019: 1003: 997:Chr 1: 173.16 – 173.16 Mb 984: 969: 965: 944: 940: 933: 918: 914: 893: 889: 882: 869: 865: 850: 846: 837: 824: 820: 805: 801: 792: 779: 775: 760: 756: 747: 732: 725: 721: 705: 570: 566: 554: 549: 540: 527: 476: 467: 414: 405: 375: 367: 363: 346: 333: 296: 275: 266: 262: 245: 232: 195: 172: 163: 159: 114: 111: 101: 94: 89: 66: 61: 44: 39: 34: 30: 26: 21: 9623:Monocyte monolayer assay 7302:Medical Subject Headings 7181:10.1182/blood.V92.7.2237 7139:10.1182/blood.V92.6.2147 7108:10.1074/jbc.272.26.16274 6541:Arthritis and Rheumatism 6124:10.3389/fimmu.2019.00551 5912:Human Molecular Genetics 5514:Proc Natl Acad Sci U S A 5384:10.1186/1475-2875-11-430 5146:10.1186/1475-2875-10-336 4693:10.1016/j.pt.2007.02.009 3732:10.1182/blood.V96.5.1681 3571:10.1074/jbc.270.44.26239 2867:10.1073/pnas.96.24.13973 2471:10.1073/pnas.90.22.10793 2049:hematopoietic stem cells 1563:interleukin-8B receptors 990:Chr 1: 159.2 – 159.21 Mb 9498:Granulocyte transfusion 6111:Frontiers in Immunology 5593:10.1126/science.1228892 5535:10.1073/pnas.1109621108 5197:10.1186/1475-2875-6-167 5044:10.1073/pnas.0912496107 4751:Annals of Human Biology 3523:10.1126/science.1228892 3472:10.1126/science.7689250 1752:ethnic populations—the 1713:and one jungle area in 1541:Interleukin-8 (IL-8) - 1464:, endothelial cells of 1290:). A third mutation (a 6680:J. Histochem. Cytochem 6216:10.1038/sj.onc.1209703 4681:Trends in Parasitology 4143:10.1124/mol.107.040915 3329:10.1084/jem.181.4.1311 2256: 500:superior frontal gyrus 488:neural layer of retina 9956:Blood antigen systems 9633:Transfusion reactions 6918:AABB Technical Manual 6721:J Immigr Minor Health 4981:Am. J. Trop. Med. Hyg 4615:10.1353/hub.2004.0053 4530:10.1353/hub.2001.0024 4374:10.1353/hub.2006.0001 3675:Journal of Immunology 3497:Plasmodium falciparum 3170:Journal of Immunology 2301:Transfusion reactions 2251:Further information: 2244: 1919:asymptomatic carriers 1850:Clinical significance 1828:) are Duffy positive. 1724:Plasmodium falciparum 1579:, neuronal cells and 1471:, the post-capillary 1388:Monodelphis domestica 1182:Genetics and genomics 692:inflammatory response 585:C-C chemokine binding 496:primary visual cortex 9966:Transfusion medicine 9613:Kleihauer–Betke test 9575:Exchange transfusion 9454:Platelet transfusion 9428:transfusion medicine 7242:Biomed. Pharmacother 6064:Molecular Psychiatry 4878:Transfus. Apher. Sci 2618:(188–189): 188–189. 2237:Transfusion medicine 2159:Lung transplantation 2149:Sardinian population 1902:Fy6 is required for 1523:Platelet factor 4 - 1483:(Asn) 16 and Asn27. 1456:it is also found on 1441:fucose at the core. 1327:transcription factor 1309:carry a silent Fy-b 1305:Most Duffy negative 1123:Plasmodium cynomolgi 504:striatum of neuraxis 330:1 H3|1 80.33 cM 291:Chromosome 1 (mouse) 189:Chromosome 1 (human) 62:List of PDB id codes 35:Available structures 9701:Blood group systems 9636:and adverse effects 9471:Fresh frozen plasma 7298:DARC+protein,+human 5924:10.1093/hmg/ddaa208 5691:2018NatSR...813851K 5585:2012Sci...338.1348M 5526:2011PNAS..10820113K 5324:2011PLoSO...619801D 5035:2010PNAS..107.5967M 4929:2012PLoSO...745219C 4837:2011NatCo...2..266H 4221:Levinson W (2004). 4095:Biochem. Soc. Trans 3515:2012Sci...338.1348M 3464:1993Sci...261.1182H 2948:10.1038/nature08149 2940:2009Natur.460..388T 2858:1999PNAS...9613973Z 2624:1950Natur.165..188C 2462:1993PNAS...9010793C 2249:, including Duffy. 2218:sickle cell anaemia 2212:Sickle cell anaemia 2204:Renal transplantion 2144:has been reported. 1631:Population genetics 1414:In yellow baboons ( 1317:-33, impairing the 1154:In 1950, the Duffy 1141:sickle cell anaemia 1117:Plasmodium knowlesi 1100:and a non-specific 697:signal transduction 454:canal of the cervix 7031:10.1007/BF00208965 6994:10.1007/BF00291239 6406:10.1093/cid/cir119 6244:J. Thromb. Haemost 5679:Scientific Reports 5082:PLOS Negl Trop Dis 4845:10.1038/ncomms1265 4646:Transfus Apher Sci 4491:Acta Anthropogenet 4107:10.1042/BST0341005 2901:J Vector Borne Dis 2667:10.1038/ng0695-224 2517:10.1038/ng0695-224 2257: 2088:Endotoxin response 1909:The protection to 1569:Scatchard analysis 1417:Papio cynocephalus 1344:at position 265). 827:ENSMUSG00000037872 665:Biological process 636:recycling endosome 624:Cellular component 578:Molecular function 508:hippocampus proper 9928: 9927: 9505:Blood substitutes 9493:White blood cells 9424:Blood transfusion 9390: 9389: 6553:10.1002/art.23545 6394:Clin. Infect. Dis 6296:Cell Host Microbe 5918:(20): 3341–3349. 5794:Nature Immunology 5579:(6112): 1348–51. 5434:10.1645/GE-2281.1 4236:978-0-07-143199-6 4015:10.1002/path.1788 3916:Am. J. Kidney Dis 3767:10.1002/path.1100 3509:(6112): 1348–51. 3231:10.1172/JCI117465 2559:(11): 1357–1363. 2422:. August 17, 2020 2292:Antibody behavior 2271:ISBT number: 008 1931:Equatorial Guinea 1653:genetic admixture 1641:African Americans 1436:Molecular biology 1376:Rattus norvegicus 1367:(rhesus monkey), 1055:), also known as 1046: 1045: 1042: 1041: 1015: 1014: 980: 979: 959: 958: 929: 928: 908: 907: 878: 877: 859: 858: 833: 832: 814: 813: 788: 787: 769: 768: 717: 716: 605:chemokine binding 562: 561: 558: 557: 536: 535: 523: 522: 480:cerebellar cortex 461: 460: 422:left uterine tube 359: 358: 258: 257: 153:ACKR1 - orthologs 85: 84: 81: 80: 45:Ortholog search: 9973: 9618:Antibody elution 9565:plateletpheresis 9531:Blood management 9514:General concepts 9417: 9410: 9403: 9394: 9393: 7380: 7373: 7366: 7357: 7356: 7286: 7265: 7236: 7218: 7193: 7183: 7158: 7120: 7110: 7101:(26): 16274–80. 7085: 7075: 7050: 7013: 6975: 6937: 6936: 6928: 6922: 6921: 6913: 6902: 6901: 6891: 6876:Immunohematology 6867: 6861: 6860: 6831: 6825: 6824: 6788: 6782: 6781: 6761: 6755: 6754: 6744: 6712: 6706: 6705: 6695: 6671: 6665: 6664: 6646: 6622: 6616: 6615: 6605: 6581: 6575: 6574: 6564: 6532: 6526: 6525: 6515: 6483: 6477: 6476: 6466: 6434: 6428: 6427: 6417: 6385: 6379: 6378: 6368: 6336: 6330: 6329: 6319: 6287: 6278: 6277: 6259: 6235: 6229: 6228: 6218: 6194: 6188: 6187: 6177: 6153: 6147: 6146: 6136: 6126: 6102: 6096: 6095: 6061: 6052: 6046: 6045: 6035: 6003: 5997: 5996: 5986: 5976: 5952: 5946: 5945: 5935: 5903: 5897: 5896: 5886: 5854: 5848: 5847: 5839: 5828: 5827: 5817: 5784: 5771: 5770: 5760: 5727: 5721: 5720: 5710: 5670: 5664: 5663: 5653: 5643: 5619: 5613: 5612: 5564: 5558: 5557: 5547: 5537: 5505: 5499: 5498: 5462: 5456: 5455: 5445: 5413: 5407: 5406: 5396: 5386: 5362: 5356: 5355: 5345: 5335: 5303: 5297: 5296: 5286: 5262: 5256: 5255: 5226: 5220: 5219: 5209: 5199: 5175: 5169: 5168: 5158: 5148: 5124: 5118: 5117: 5107: 5097: 5073: 5067: 5066: 5056: 5046: 5013: 5007: 5006: 4996: 4972: 4961: 4960: 4950: 4940: 4908: 4902: 4901: 4873: 4867: 4866: 4856: 4816: 4810: 4809: 4789: 4783: 4782: 4746: 4740: 4739: 4711: 4705: 4704: 4676: 4670: 4669: 4641: 4635: 4634: 4597: 4591: 4590: 4580: 4565:Immunohematology 4556: 4550: 4549: 4513: 4507: 4506: 4486: 4480: 4479: 4443: 4437: 4436: 4400: 4394: 4393: 4357: 4351: 4350: 4326: 4320: 4319: 4291: 4285: 4284: 4274: 4250: 4241: 4240: 4228: 4218: 4212: 4211: 4201: 4169: 4163: 4162: 4125: 4119: 4118: 4101:(Pt 6): 1005–8. 4090: 4084: 4083: 4065: 4041: 4035: 4034: 3997: 3991: 3990: 3980: 3956: 3950: 3949: 3931: 3910: 3904: 3903: 3893: 3869: 3863: 3862: 3834: 3828: 3827: 3817: 3793: 3787: 3786: 3750: 3744: 3743: 3715: 3709: 3708: 3698: 3666: 3660: 3659: 3631: 3625: 3624: 3614: 3590: 3584: 3583: 3573: 3564:(44): 26239–45. 3549: 3543: 3542: 3490: 3484: 3483: 3458:(5125): 1182–4. 3446:Plasmodium vivax 3439: 3433: 3432: 3422: 3398: 3392: 3391: 3381: 3357: 3351: 3350: 3340: 3308: 3302: 3301: 3283: 3274:(7): 1013–1015. 3259: 3253: 3252: 3242: 3210: 3204: 3203: 3185: 3161: 3155: 3154: 3118: 3109: 3108: 3098: 3066: 3060: 3059: 3023: 3017: 3016: 3006: 2989:(6): 1260–1267. 2974: 2968: 2967: 2934:(7253): 388–91. 2923: 2917: 2916: 2896: 2890: 2889: 2879: 2869: 2837: 2831: 2830: 2820: 2788: 2782: 2781: 2771: 2739: 2730: 2729: 2693: 2687: 2686: 2650: 2644: 2643: 2632:10.1038/165188b0 2607: 2601: 2600: 2593: 2587: 2586: 2576: 2543: 2537: 2536: 2500: 2494: 2493: 2483: 2473: 2441: 2432: 2431: 2429: 2427: 2412: 2406: 2405: 2394: 2388: 2387: 2376: 2370: 2360: 2349: 2339: 2274:Gene symbol: FY 2264:Transfusion data 2167:Multiple myeloma 1986:Plasmodium vivax 1729:Plasmodium vivax 1452:and circulating 1400:Canis familiaris 1350:Papua New Guinea 1226:at position 42: 1111:Plasmodium vivax 1098:membrane protein 1028: 1027: 999: 992: 975: 963: 962: 954: 938: 937: 934:RefSeq (protein) 924: 912: 911: 903: 887: 886: 863: 862: 844: 843: 818: 817: 799: 798: 773: 772: 754: 753: 723: 722: 687:defense response 568: 567: 547: 546: 532: 472: 470:Top expressed in 465: 464: 410: 408:Top expressed in 403: 402: 382: 381: 365: 364: 355: 342: 331: 316: 309: 303: 292: 280: 264: 263: 254: 241: 230: 215: 208: 202: 191: 177: 161: 160: 155: 106: 99: 76: 59: 58: 53: 32: 31: 19: 18: 9981: 9980: 9976: 9975: 9974: 9972: 9971: 9970: 9931: 9930: 9929: 9924: 9719:Secretor status 9695: 9635: 9627: 9584: 9545: 9509: 9486:Cryosupernatant 9481:Cryoprecipitate 9461:Red blood cells 9430: 9421: 9391: 9386: 9190: 8984: 8733: 8417: 8140: 7800: 7398: 7384: 7330:Population data 7294: 7289: 7203:Br. J. Haematol 6945: 6943:Further reading 6940: 6929: 6925: 6914: 6905: 6868: 6864: 6832: 6828: 6789: 6785: 6766:Ann. Transplant 6762: 6758: 6713: 6709: 6672: 6668: 6644:10.1002/hon.887 6623: 6619: 6582: 6578: 6533: 6529: 6504:10.1038/ng.3368 6498:(11): 1272–81. 6492:Nature Genetics 6484: 6480: 6435: 6431: 6400:(10): 1248–56. 6386: 6382: 6351:(13): 2783–92. 6337: 6333: 6288: 6281: 6236: 6232: 6209:(54): 7201–11. 6195: 6191: 6154: 6150: 6103: 6099: 6059: 6053: 6049: 6004: 6000: 5967:(1): e1000360. 5953: 5949: 5904: 5900: 5855: 5851: 5840: 5831: 5806:10.1038/ni.3763 5785: 5774: 5743:(10): 1017–22. 5728: 5724: 5671: 5667: 5634:(6): e1003420. 5620: 5616: 5565: 5561: 5520:(50): 20113–8. 5506: 5502: 5463: 5459: 5414: 5410: 5363: 5359: 5304: 5300: 5263: 5259: 5227: 5223: 5176: 5172: 5125: 5121: 5074: 5070: 5029:(13): 5967–71. 5014: 5010: 4973: 4964: 4909: 4905: 4874: 4870: 4817: 4813: 4790: 4786: 4747: 4743: 4712: 4708: 4677: 4673: 4642: 4638: 4598: 4594: 4557: 4553: 4514: 4510: 4487: 4483: 4444: 4440: 4405:J. Forensic Sci 4401: 4397: 4358: 4354: 4335:Genet. Mol. Res 4327: 4323: 4296:N. Engl. J. Med 4292: 4288: 4251: 4244: 4237: 4219: 4215: 4190:10.1038/ni.1675 4170: 4166: 4126: 4122: 4091: 4087: 4050:Transplantation 4042: 4038: 3998: 3994: 3957: 3953: 3929:10.1.1.408.1801 3911: 3907: 3870: 3866: 3835: 3831: 3808:(4): 1491–500. 3794: 3790: 3751: 3747: 3716: 3712: 3681:(10): 5244–51. 3667: 3663: 3632: 3628: 3591: 3587: 3550: 3546: 3491: 3487: 3440: 3436: 3413:(26): 17730–3. 3399: 3395: 3358: 3354: 3309: 3305: 3260: 3256: 3219:J. Clin. Invest 3211: 3207: 3162: 3158: 3119: 3112: 3081:(2–3): 93–105. 3067: 3063: 3024: 3020: 2975: 2971: 2924: 2920: 2897: 2893: 2852:(24): 13973–7. 2838: 2834: 2789: 2785: 2740: 2733: 2694: 2690: 2651: 2647: 2608: 2604: 2595: 2594: 2590: 2544: 2540: 2501: 2497: 2456:(22): 10793–7. 2442: 2435: 2425: 2423: 2414: 2413: 2409: 2396: 2395: 2391: 2378: 2377: 2373: 2361: 2352: 2340: 2331: 2327: 2316: 2303: 2294: 2286: 2266: 2255: 2239: 2227: 2214: 2206: 2193: 2191:Prostate cancer 2185: 2177: 2169: 2161: 2138: 2099: 2090: 2074: 2057: 2037: 2022: 1864: 1852: 1770:(also known as 1743:Southern Europe 1633: 1438: 1358:Pan troglodytes 1184: 1136: 1091:red blood cells 1057:Fy glycoprotein 1037:View/Edit Mouse 1032:View/Edit Human 995: 988: 985:Location (UCSC) 971: 950: 946: 920: 899: 895: 808:ENSG00000213088 701: 660: 646:plasma membrane 619: 610:protein binding 528: 519: 514: 510: 506: 502: 498: 494: 490: 486: 484:layer of retina 482: 468: 457: 452: 450:coronary artery 448: 444: 440: 436: 432: 428: 424: 420: 406: 350: 337: 329: 319: 318: 317: 310: 290: 267:Gene location ( 249: 236: 228: 218: 217: 216: 209: 187: 164:Gene location ( 115: 102: 95: 68: 46: 17: 12: 11: 5: 9979: 9969: 9968: 9963: 9958: 9953: 9948: 9943: 9926: 9925: 9923: 9922: 9917: 9912: 9907: 9902: 9897: 9892: 9887: 9878: 9873: 9868: 9863: 9858: 9853: 9848: 9843: 9838: 9833: 9828: 9818: 9813: 9808: 9803: 9798: 9793: 9788: 9783: 9778: 9773: 9768: 9763: 9758: 9753: 9748: 9743: 9738: 9733: 9728: 9723: 9722: 9721: 9711: 9705: 9703: 9697: 9696: 9694: 9693: 9688: 9686:Serum sickness 9683: 9682: 9681: 9676: 9665: 9660: 9655: 9650: 9645: 9639: 9637: 9629: 9628: 9626: 9625: 9620: 9615: 9610: 9605: 9604: 9603: 9601:Cross-matching 9592: 9590: 9586: 9585: 9583: 9582: 9577: 9572: 9561:plasmapheresis 9553: 9551: 9547: 9546: 9544: 9543: 9538: 9533: 9528: 9526:Blood donation 9523: 9517: 9515: 9511: 9510: 9508: 9507: 9502: 9501: 9500: 9490: 9489: 9488: 9483: 9478: 9473: 9463: 9458: 9457: 9456: 9446: 9440: 9438: 9436:Blood products 9432: 9431: 9420: 9419: 9412: 9405: 9397: 9388: 9387: 9385: 9384: 9379: 9374: 9369: 9364: 9359: 9354: 9349: 9344: 9339: 9334: 9329: 9324: 9319: 9314: 9309: 9304: 9299: 9294: 9289: 9284: 9279: 9274: 9269: 9264: 9259: 9254: 9249: 9244: 9239: 9234: 9229: 9224: 9219: 9214: 9209: 9204: 9198: 9196: 9192: 9191: 9189: 9188: 9183: 9178: 9173: 9168: 9163: 9158: 9153: 9148: 9143: 9138: 9133: 9128: 9123: 9118: 9113: 9108: 9103: 9098: 9093: 9088: 9083: 9078: 9073: 9068: 9063: 9058: 9053: 9048: 9043: 9038: 9033: 9028: 9023: 9018: 9013: 9008: 9003: 8998: 8992: 8990: 8986: 8985: 8983: 8982: 8977: 8968: 8963: 8958: 8953: 8948: 8943: 8938: 8933: 8928: 8923: 8922: 8921: 8916: 8906: 8901: 8896: 8891: 8886: 8881: 8876: 8871: 8866: 8861: 8856: 8851: 8846: 8841: 8835: 8826: 8821: 8820: 8819: 8814: 8804: 8799: 8798: 8797: 8792: 8782: 8777: 8772: 8767: 8762: 8757: 8752: 8747: 8741: 8739: 8735: 8734: 8732: 8731: 8726: 8721: 8716: 8711: 8706: 8701: 8696: 8691: 8686: 8681: 8676: 8671: 8666: 8661: 8656: 8651: 8646: 8645: 8644: 8639: 8629: 8624: 8619: 8614: 8613: 8612: 8607: 8602: 8592: 8587: 8582: 8577: 8572: 8571: 8570: 8565: 8555: 8550: 8545: 8540: 8535: 8530: 8525: 8524: 8523: 8518: 8508: 8502: 8497: 8492: 8487: 8478: 8473: 8472: 8471: 8466: 8461: 8451: 8446: 8441: 8436: 8431: 8425: 8423: 8419: 8418: 8416: 8415: 8410: 8405: 8400: 8395: 8390: 8385: 8380: 8375: 8370: 8365: 8360: 8355: 8350: 8345: 8340: 8335: 8330: 8325: 8320: 8315: 8310: 8305: 8300: 8295: 8290: 8289: 8288: 8283: 8273: 8272: 8271: 8266: 8256: 8251: 8246: 8241: 8236: 8231: 8226: 8221: 8216: 8211: 8206: 8201: 8196: 8195: 8194: 8189: 8179: 8174: 8169: 8164: 8159: 8154: 8148: 8146: 8142: 8141: 8139: 8138: 8133: 8128: 8123: 8118: 8113: 8108: 8103: 8098: 8089: 8084: 8079: 8074: 8069: 8064: 8063: 8062: 8057: 8052: 8047: 8042: 8037: 8027: 8022: 8017: 8012: 8007: 8002: 8001: 8000: 7995: 7985: 7980: 7975: 7970: 7965: 7960: 7955: 7950: 7945: 7944: 7943: 7938: 7933: 7928: 7923: 7918: 7908: 7907: 7906: 7901: 7896: 7886: 7881: 7880: 7879: 7874: 7869: 7859: 7854: 7849: 7844: 7839: 7834: 7829: 7824: 7819: 7814: 7808: 7806: 7802: 7801: 7799: 7798: 7793: 7792: 7791: 7786: 7781: 7776: 7771: 7766: 7756: 7751: 7746: 7741: 7736: 7731: 7726: 7725: 7724: 7719: 7714: 7709: 7699: 7694: 7689: 7684: 7679: 7674: 7669: 7664: 7659: 7654: 7653: 7652: 7647: 7637: 7632: 7627: 7622: 7617: 7612: 7607: 7602: 7597: 7592: 7587: 7582: 7577: 7572: 7567: 7566: 7565: 7560: 7550: 7545: 7540: 7535: 7534: 7533: 7528: 7523: 7518: 7508: 7503: 7498: 7497: 7496: 7486: 7481: 7476: 7471: 7466: 7465: 7464: 7459: 7454: 7444: 7439: 7438: 7437: 7432: 7427: 7422: 7417: 7406: 7404: 7400: 7399: 7383: 7382: 7375: 7368: 7360: 7354: 7353: 7332: 7327: 7322: 7305: 7293: 7292:External links 7290: 7288: 7287: 7266: 7237: 7209:(4): 1184–91. 7194: 7174:(7): 2237–43. 7159: 7133:(6): 2147–56. 7121: 7086: 7051: 7014: 6976: 6946: 6944: 6941: 6939: 6938: 6923: 6903: 6862: 6826: 6783: 6756: 6707: 6666: 6617: 6590:Eur. Respir. J 6576: 6547:(7): 1968–73. 6527: 6478: 6429: 6380: 6331: 6279: 6230: 6189: 6148: 6097: 6070:(3): 328–337. 6047: 6018:(3): 317–320. 6012:Blood Advances 5998: 5947: 5898: 5869:(3): 317–320. 5863:Blood Advances 5849: 5829: 5800:(7): 753–761. 5772: 5722: 5665: 5614: 5559: 5500: 5473:(5): 1049–53. 5457: 5428:(1): 225–227. 5408: 5357: 5298: 5284:10.1086/644510 5271:J. Infect. Dis 5257: 5238:(10): 1042–4. 5221: 5170: 5119: 5068: 5008: 4962: 4903: 4868: 4811: 4784: 4741: 4722:(2): 299–303. 4706: 4671: 4636: 4592: 4551: 4508: 4497:(3–4): 173–9. 4481: 4438: 4395: 4352: 4321: 4286: 4242: 4235: 4213: 4164: 4137:(5): 1362–70. 4131:Mol. Pharmacol 4120: 4085: 4036: 3992: 3951: 3905: 3884:(4): 1546–56. 3864: 3829: 3788: 3745: 3710: 3661: 3626: 3605:(11): 7835–8. 3585: 3544: 3485: 3434: 3393: 3372:(11): 7835–8. 3352: 3303: 3268:Cell Stem Cell 3254: 3205: 3176:(6): 2882–90. 3156: 3110: 3061: 3034:(7): 497–505. 3028:Immunogenetics 3018: 2969: 2918: 2891: 2832: 2809:10.1086/338628 2783: 2760:10.1086/302879 2754:(5): 1669–79. 2731: 2688: 2645: 2602: 2588: 2538: 2495: 2433: 2407: 2389: 2371: 2350: 2328: 2326: 2323: 2315: 2312: 2302: 2299: 2293: 2290: 2285: 2282: 2265: 2262: 2238: 2235: 2233:erythrocytes. 2226: 2223: 2213: 2210: 2205: 2202: 2192: 2189: 2184: 2181: 2176: 2173: 2168: 2165: 2160: 2157: 2137: 2134: 2098: 2095: 2089: 2086: 2073: 2070: 2056: 2053: 2036: 2033: 2021: 2018: 1975:Amazonas State 1863: 1860: 1851: 1848: 1840: 1839: 1832: 1829: 1802: 1786:Horn of Africa 1778: 1775: 1764: 1761: 1746: 1732: 1715:Middle Andaman 1695: 1688: 1671: 1670: 1667: 1664: 1632: 1629: 1550:amino terminus 1546: 1545: 1539: 1533: 1527: 1521: 1511: 1510: 1500: 1494: 1458:Purkinje cells 1437: 1434: 1370:Pongo pygmaeus 1364:Macaca mulatta 1361:(chimpanzee), 1244:point mutation 1183: 1180: 1135: 1132: 1044: 1043: 1040: 1039: 1034: 1024: 1023: 1017: 1016: 1013: 1012: 1010: 1008: 1001: 1000: 993: 986: 982: 981: 978: 977: 967: 966: 960: 957: 956: 942: 941: 935: 931: 930: 927: 926: 916: 915: 909: 906: 905: 891: 890: 884: 880: 879: 876: 875: 867: 866: 860: 857: 856: 848: 847: 841: 835: 834: 831: 830: 822: 821: 815: 812: 811: 803: 802: 796: 790: 789: 786: 785: 777: 776: 770: 767: 766: 758: 757: 751: 745: 744: 739: 734: 730: 729: 719: 718: 715: 714: 703: 702: 700: 699: 694: 689: 684: 679: 674: 668: 666: 662: 661: 659: 658: 653: 651:early endosome 648: 643: 638: 633: 627: 625: 621: 620: 618: 617: 612: 607: 602: 597: 592: 587: 581: 579: 575: 574: 564: 563: 560: 559: 556: 555: 552: 551: 544: 538: 537: 534: 533: 525: 524: 521: 520: 518: 517: 513: 512:olfactory bulb 509: 505: 501: 497: 493: 489: 485: 481: 477: 474: 473: 462: 459: 458: 456: 455: 451: 447: 443: 439: 435: 431: 427: 426:gastric mucosa 423: 419: 415: 412: 411: 399: 398: 390: 379: 373: 372: 369:RNA expression 361: 360: 357: 356: 348: 344: 343: 335: 332: 327: 321: 320: 311: 304: 298: 294: 293: 288: 282: 281: 273: 272: 260: 259: 256: 255: 247: 243: 242: 234: 231: 226: 220: 219: 210: 203: 197: 193: 192: 185: 179: 178: 170: 169: 157: 156: 113: 109: 108: 100: 92: 91: 87: 86: 83: 82: 79: 78: 64: 63: 55: 54: 43: 37: 36: 28: 27: 24: 23: 15: 9: 6: 4: 3: 2: 9978: 9967: 9964: 9962: 9959: 9957: 9954: 9952: 9951:Immune system 9949: 9947: 9944: 9942: 9939: 9938: 9936: 9921: 9918: 9916: 9913: 9911: 9908: 9906: 9903: 9901: 9898: 9896: 9893: 9891: 9888: 9886: 9882: 9879: 9877: 9874: 9872: 9869: 9867: 9864: 9862: 9859: 9857: 9854: 9852: 9849: 9847: 9844: 9842: 9839: 9837: 9834: 9832: 9829: 9826: 9822: 9819: 9817: 9814: 9812: 9809: 9807: 9804: 9802: 9799: 9797: 9794: 9792: 9789: 9787: 9784: 9782: 9779: 9777: 9774: 9772: 9769: 9767: 9764: 9762: 9759: 9757: 9754: 9752: 9749: 9747: 9744: 9742: 9739: 9737: 9736:Chido-Rodgers 9734: 9732: 9729: 9727: 9724: 9720: 9717: 9716: 9715: 9712: 9710: 9707: 9706: 9704: 9702: 9698: 9692: 9689: 9687: 9684: 9680: 9677: 9675: 9672: 9671: 9669: 9666: 9664: 9661: 9659: 9656: 9654: 9651: 9649: 9646: 9644: 9641: 9640: 9638: 9634: 9630: 9624: 9621: 9619: 9616: 9614: 9611: 9609: 9606: 9602: 9599: 9598: 9597: 9594: 9593: 9591: 9587: 9581: 9578: 9576: 9573: 9570: 9569:leukapheresis 9566: 9562: 9558: 9555: 9554: 9552: 9548: 9542: 9539: 9537: 9534: 9532: 9529: 9527: 9524: 9522: 9519: 9518: 9516: 9512: 9506: 9503: 9499: 9496: 9495: 9494: 9491: 9487: 9484: 9482: 9479: 9477: 9474: 9472: 9469: 9468: 9467: 9464: 9462: 9459: 9455: 9452: 9451: 9450: 9447: 9445: 9442: 9441: 9439: 9437: 9433: 9429: 9425: 9418: 9413: 9411: 9406: 9404: 9399: 9398: 9395: 9383: 9380: 9378: 9375: 9373: 9370: 9368: 9365: 9363: 9360: 9358: 9355: 9353: 9350: 9348: 9345: 9343: 9340: 9338: 9335: 9333: 9330: 9328: 9325: 9323: 9320: 9318: 9315: 9313: 9310: 9308: 9305: 9303: 9300: 9298: 9295: 9293: 9290: 9288: 9285: 9283: 9280: 9278: 9275: 9273: 9270: 9268: 9265: 9263: 9260: 9258: 9255: 9253: 9250: 9248: 9245: 9243: 9240: 9238: 9235: 9233: 9230: 9228: 9225: 9223: 9220: 9218: 9215: 9213: 9210: 9208: 9205: 9203: 9200: 9199: 9197: 9193: 9187: 9184: 9182: 9179: 9177: 9174: 9172: 9169: 9167: 9164: 9162: 9159: 9157: 9154: 9152: 9149: 9147: 9144: 9142: 9139: 9137: 9134: 9132: 9129: 9127: 9124: 9122: 9119: 9117: 9114: 9112: 9109: 9107: 9104: 9102: 9099: 9097: 9094: 9092: 9089: 9087: 9084: 9082: 9079: 9077: 9074: 9072: 9069: 9067: 9064: 9062: 9059: 9057: 9054: 9052: 9049: 9047: 9044: 9042: 9039: 9037: 9034: 9032: 9029: 9027: 9024: 9022: 9019: 9017: 9014: 9012: 9009: 9007: 9004: 9002: 8999: 8997: 8994: 8993: 8991: 8987: 8981: 8978: 8976: 8972: 8969: 8967: 8964: 8962: 8959: 8957: 8954: 8952: 8949: 8947: 8944: 8942: 8939: 8937: 8934: 8932: 8929: 8927: 8924: 8920: 8917: 8915: 8912: 8911: 8910: 8907: 8905: 8902: 8900: 8897: 8895: 8892: 8890: 8887: 8885: 8882: 8880: 8877: 8875: 8872: 8870: 8867: 8865: 8862: 8860: 8857: 8855: 8852: 8850: 8847: 8845: 8842: 8839: 8836: 8834: 8830: 8827: 8825: 8822: 8818: 8815: 8813: 8810: 8809: 8808: 8805: 8803: 8800: 8796: 8793: 8791: 8788: 8787: 8786: 8783: 8781: 8778: 8776: 8773: 8771: 8768: 8766: 8763: 8761: 8758: 8756: 8753: 8751: 8748: 8746: 8743: 8742: 8740: 8736: 8730: 8727: 8725: 8722: 8720: 8717: 8715: 8712: 8710: 8707: 8705: 8702: 8700: 8697: 8695: 8692: 8690: 8687: 8685: 8682: 8680: 8677: 8675: 8672: 8670: 8667: 8665: 8662: 8660: 8657: 8655: 8652: 8650: 8647: 8643: 8640: 8638: 8635: 8634: 8633: 8630: 8628: 8625: 8623: 8620: 8618: 8615: 8611: 8608: 8606: 8603: 8601: 8598: 8597: 8596: 8593: 8591: 8588: 8586: 8583: 8581: 8578: 8576: 8573: 8569: 8566: 8564: 8561: 8560: 8559: 8556: 8554: 8551: 8549: 8546: 8544: 8541: 8539: 8536: 8534: 8531: 8529: 8526: 8522: 8519: 8517: 8514: 8513: 8512: 8509: 8506: 8503: 8501: 8498: 8496: 8493: 8491: 8488: 8486: 8482: 8479: 8477: 8474: 8470: 8467: 8465: 8462: 8460: 8457: 8456: 8455: 8452: 8450: 8447: 8445: 8442: 8440: 8437: 8435: 8432: 8430: 8427: 8426: 8424: 8420: 8414: 8411: 8409: 8406: 8404: 8401: 8399: 8396: 8394: 8391: 8389: 8386: 8384: 8381: 8379: 8376: 8374: 8371: 8369: 8366: 8364: 8361: 8359: 8356: 8354: 8351: 8349: 8346: 8344: 8341: 8339: 8336: 8334: 8331: 8329: 8326: 8324: 8321: 8319: 8316: 8314: 8311: 8309: 8306: 8304: 8301: 8299: 8296: 8294: 8291: 8287: 8284: 8282: 8279: 8278: 8277: 8274: 8270: 8267: 8265: 8262: 8261: 8260: 8257: 8255: 8252: 8250: 8247: 8245: 8242: 8240: 8237: 8235: 8232: 8230: 8227: 8225: 8222: 8220: 8217: 8215: 8212: 8210: 8207: 8205: 8202: 8200: 8197: 8193: 8190: 8188: 8185: 8184: 8183: 8180: 8178: 8175: 8173: 8170: 8168: 8165: 8163: 8160: 8158: 8155: 8153: 8150: 8149: 8147: 8143: 8137: 8134: 8132: 8129: 8127: 8124: 8122: 8119: 8117: 8114: 8112: 8109: 8107: 8104: 8102: 8099: 8097: 8093: 8090: 8088: 8085: 8083: 8080: 8078: 8075: 8073: 8070: 8068: 8065: 8061: 8058: 8056: 8053: 8051: 8048: 8046: 8043: 8041: 8038: 8036: 8033: 8032: 8031: 8028: 8026: 8023: 8021: 8018: 8016: 8013: 8011: 8008: 8006: 8003: 7999: 7996: 7994: 7991: 7990: 7989: 7986: 7984: 7981: 7979: 7976: 7974: 7971: 7969: 7966: 7964: 7961: 7959: 7956: 7954: 7951: 7949: 7946: 7942: 7939: 7937: 7934: 7932: 7929: 7927: 7924: 7922: 7919: 7917: 7914: 7913: 7912: 7909: 7905: 7902: 7900: 7897: 7895: 7892: 7891: 7890: 7887: 7885: 7882: 7878: 7875: 7873: 7870: 7868: 7865: 7864: 7863: 7860: 7858: 7855: 7853: 7850: 7848: 7845: 7843: 7840: 7838: 7835: 7833: 7830: 7828: 7825: 7823: 7820: 7818: 7815: 7813: 7810: 7809: 7807: 7803: 7797: 7794: 7790: 7787: 7785: 7782: 7780: 7777: 7775: 7772: 7770: 7767: 7765: 7762: 7761: 7760: 7757: 7755: 7752: 7750: 7747: 7745: 7742: 7740: 7737: 7735: 7732: 7730: 7727: 7723: 7720: 7718: 7715: 7713: 7710: 7708: 7705: 7704: 7703: 7700: 7698: 7695: 7693: 7690: 7688: 7685: 7683: 7680: 7678: 7675: 7673: 7670: 7668: 7665: 7663: 7660: 7658: 7655: 7651: 7648: 7646: 7643: 7642: 7641: 7638: 7636: 7633: 7631: 7628: 7626: 7623: 7621: 7618: 7616: 7613: 7611: 7608: 7606: 7603: 7601: 7598: 7596: 7593: 7591: 7588: 7586: 7583: 7581: 7578: 7576: 7573: 7571: 7568: 7564: 7561: 7559: 7556: 7555: 7554: 7551: 7549: 7546: 7544: 7541: 7539: 7536: 7532: 7529: 7527: 7524: 7522: 7519: 7517: 7514: 7513: 7512: 7509: 7507: 7504: 7502: 7499: 7495: 7492: 7491: 7490: 7487: 7485: 7482: 7480: 7477: 7475: 7472: 7470: 7467: 7463: 7460: 7458: 7455: 7453: 7450: 7449: 7448: 7445: 7443: 7440: 7436: 7433: 7431: 7428: 7426: 7423: 7421: 7418: 7416: 7413: 7412: 7411: 7408: 7407: 7405: 7401: 7396: 7392: 7388: 7381: 7376: 7374: 7369: 7367: 7362: 7361: 7358: 7351: 7347: 7346: 7341: 7337: 7333: 7331: 7328: 7326: 7323: 7321: 7317: 7313: 7309: 7306: 7303: 7299: 7296: 7295: 7284: 7280: 7276: 7272: 7267: 7263: 7259: 7255: 7251: 7248:(10): 436–9. 7247: 7243: 7238: 7234: 7230: 7226: 7222: 7217: 7212: 7208: 7204: 7200: 7195: 7191: 7187: 7182: 7177: 7173: 7169: 7165: 7160: 7156: 7152: 7148: 7144: 7140: 7136: 7132: 7128: 7122: 7118: 7114: 7109: 7104: 7100: 7096: 7095:J. Biol. Chem 7092: 7087: 7083: 7079: 7074: 7069: 7065: 7061: 7057: 7052: 7048: 7044: 7040: 7036: 7032: 7028: 7025:(4): 407–10. 7024: 7020: 7015: 7011: 7007: 7003: 6999: 6995: 6991: 6987: 6983: 6977: 6973: 6969: 6965: 6961: 6958:(4): 269–76. 6957: 6953: 6948: 6947: 6934: 6927: 6919: 6912: 6910: 6908: 6899: 6895: 6890: 6885: 6881: 6877: 6873: 6866: 6858: 6854: 6850: 6846: 6843:(1): 116–22. 6842: 6838: 6837:Clin. Immunol 6830: 6822: 6818: 6814: 6810: 6806: 6802: 6799:(5): 917–24. 6798: 6794: 6787: 6779: 6775: 6771: 6767: 6760: 6752: 6748: 6743: 6738: 6734: 6730: 6726: 6722: 6718: 6711: 6703: 6699: 6694: 6689: 6686:(2): 159–66. 6685: 6681: 6677: 6670: 6662: 6658: 6654: 6650: 6645: 6640: 6636: 6632: 6631:Hematol Oncol 6628: 6621: 6613: 6609: 6604: 6599: 6596:(1): 167–75. 6595: 6591: 6587: 6580: 6572: 6568: 6563: 6558: 6554: 6550: 6546: 6542: 6538: 6531: 6523: 6519: 6514: 6509: 6505: 6501: 6497: 6493: 6489: 6482: 6474: 6470: 6465: 6460: 6456: 6452: 6448: 6444: 6440: 6433: 6425: 6421: 6416: 6411: 6407: 6403: 6399: 6395: 6391: 6384: 6376: 6372: 6367: 6362: 6358: 6354: 6350: 6346: 6342: 6335: 6327: 6323: 6318: 6313: 6309: 6305: 6301: 6297: 6293: 6286: 6284: 6275: 6271: 6267: 6263: 6258: 6253: 6250:(4): 634–40. 6249: 6245: 6241: 6234: 6226: 6222: 6217: 6212: 6208: 6204: 6200: 6193: 6185: 6181: 6176: 6171: 6167: 6163: 6159: 6152: 6144: 6140: 6135: 6130: 6125: 6120: 6116: 6112: 6108: 6101: 6093: 6089: 6085: 6081: 6077: 6073: 6069: 6065: 6058: 6051: 6043: 6039: 6034: 6029: 6025: 6021: 6017: 6013: 6009: 6002: 5994: 5990: 5985: 5980: 5975: 5970: 5966: 5962: 5961:PLOS Genetics 5958: 5951: 5943: 5939: 5934: 5929: 5925: 5921: 5917: 5913: 5909: 5902: 5894: 5890: 5885: 5880: 5876: 5872: 5868: 5864: 5860: 5853: 5845: 5838: 5836: 5834: 5825: 5821: 5816: 5811: 5807: 5803: 5799: 5795: 5791: 5783: 5781: 5779: 5777: 5768: 5764: 5759: 5754: 5750: 5746: 5742: 5738: 5734: 5726: 5718: 5714: 5709: 5704: 5700: 5696: 5692: 5688: 5684: 5680: 5676: 5669: 5661: 5657: 5652: 5647: 5642: 5637: 5633: 5629: 5625: 5618: 5610: 5606: 5602: 5598: 5594: 5590: 5586: 5582: 5578: 5574: 5570: 5563: 5555: 5551: 5546: 5541: 5536: 5531: 5527: 5523: 5519: 5515: 5511: 5504: 5496: 5492: 5488: 5484: 5480: 5476: 5472: 5468: 5467:Parasitol Res 5461: 5453: 5449: 5444: 5439: 5435: 5431: 5427: 5423: 5419: 5412: 5404: 5400: 5395: 5390: 5385: 5380: 5376: 5372: 5368: 5361: 5353: 5349: 5344: 5339: 5334: 5329: 5325: 5321: 5318:(5): e19801. 5317: 5313: 5309: 5302: 5294: 5290: 5285: 5280: 5277:(9): 1465–9. 5276: 5272: 5268: 5261: 5253: 5249: 5245: 5241: 5237: 5233: 5225: 5217: 5213: 5208: 5203: 5198: 5193: 5189: 5185: 5181: 5174: 5166: 5162: 5157: 5152: 5147: 5142: 5138: 5134: 5130: 5123: 5115: 5111: 5106: 5101: 5096: 5091: 5087: 5083: 5079: 5072: 5064: 5060: 5055: 5050: 5045: 5040: 5036: 5032: 5028: 5024: 5020: 5012: 5004: 5000: 4995: 4990: 4987:(4): 575–81. 4986: 4982: 4978: 4971: 4969: 4967: 4958: 4954: 4949: 4944: 4939: 4934: 4930: 4926: 4923:(9): e45219. 4922: 4918: 4914: 4907: 4899: 4895: 4891: 4887: 4883: 4879: 4872: 4864: 4860: 4855: 4850: 4846: 4842: 4838: 4834: 4830: 4826: 4822: 4815: 4807: 4803: 4800:(3): 417–20. 4799: 4796:(in French). 4795: 4788: 4780: 4776: 4772: 4768: 4764: 4760: 4757:(4): 406–15. 4756: 4752: 4745: 4737: 4733: 4729: 4725: 4721: 4717: 4710: 4702: 4698: 4694: 4690: 4686: 4682: 4675: 4667: 4663: 4659: 4655: 4651: 4647: 4640: 4632: 4628: 4624: 4620: 4616: 4612: 4609:(4): 527–41. 4608: 4604: 4596: 4588: 4584: 4579: 4574: 4570: 4566: 4562: 4555: 4547: 4543: 4539: 4535: 4531: 4527: 4524:(2): 307–13. 4523: 4519: 4512: 4504: 4500: 4496: 4492: 4485: 4477: 4473: 4469: 4465: 4461: 4457: 4454:(3): 237–40. 4453: 4449: 4442: 4434: 4430: 4426: 4422: 4418: 4414: 4411:(2): 357–60. 4410: 4406: 4399: 4391: 4387: 4383: 4379: 4375: 4371: 4368:(5): 619–37. 4367: 4363: 4356: 4348: 4344: 4341:(2): 166–73. 4340: 4336: 4332: 4325: 4317: 4313: 4309: 4305: 4301: 4297: 4290: 4282: 4278: 4273: 4268: 4265:(8): 738–42. 4264: 4260: 4256: 4249: 4247: 4238: 4232: 4227: 4226: 4217: 4209: 4205: 4200: 4195: 4191: 4187: 4183: 4179: 4175: 4168: 4160: 4156: 4152: 4148: 4144: 4140: 4136: 4132: 4124: 4116: 4112: 4108: 4104: 4100: 4096: 4089: 4081: 4077: 4073: 4069: 4064: 4059: 4056:(7): 1030–4. 4055: 4051: 4047: 4040: 4032: 4028: 4024: 4020: 4016: 4012: 4008: 4004: 3996: 3988: 3984: 3979: 3974: 3971:(3): 309–13. 3970: 3966: 3962: 3955: 3947: 3943: 3939: 3935: 3930: 3925: 3922:(3): 518–31. 3921: 3917: 3909: 3901: 3897: 3892: 3887: 3883: 3879: 3875: 3868: 3860: 3856: 3852: 3848: 3845:(6): 687–94. 3844: 3840: 3833: 3825: 3821: 3816: 3811: 3807: 3803: 3799: 3792: 3784: 3780: 3776: 3772: 3768: 3764: 3761:(1): 108–16. 3760: 3756: 3749: 3741: 3737: 3733: 3729: 3726:(5): 1681–4. 3725: 3721: 3714: 3706: 3702: 3697: 3692: 3688: 3684: 3680: 3676: 3672: 3665: 3657: 3653: 3649: 3645: 3641: 3637: 3630: 3622: 3618: 3613: 3608: 3604: 3600: 3599:J. Biol. Chem 3596: 3589: 3581: 3577: 3572: 3567: 3563: 3559: 3558:J. Biol. Chem 3555: 3548: 3540: 3536: 3532: 3528: 3524: 3520: 3516: 3512: 3508: 3504: 3500: 3498: 3489: 3481: 3477: 3473: 3469: 3465: 3461: 3457: 3453: 3449: 3447: 3438: 3430: 3426: 3421: 3416: 3412: 3408: 3407:J. Biol. Chem 3404: 3397: 3389: 3385: 3380: 3375: 3371: 3367: 3366:J. Biol. Chem 3363: 3356: 3348: 3344: 3339: 3334: 3330: 3326: 3323:(4): 1311–7. 3322: 3318: 3314: 3307: 3299: 3295: 3291: 3287: 3282: 3277: 3273: 3269: 3265: 3258: 3250: 3246: 3241: 3236: 3232: 3228: 3225:(3): 985–91. 3224: 3220: 3216: 3209: 3201: 3197: 3193: 3189: 3184: 3179: 3175: 3171: 3167: 3160: 3152: 3148: 3144: 3140: 3136: 3132: 3129:(8): 949–53. 3128: 3124: 3117: 3115: 3106: 3102: 3097: 3092: 3088: 3084: 3080: 3076: 3072: 3065: 3057: 3053: 3049: 3045: 3041: 3037: 3033: 3029: 3022: 3014: 3010: 3005: 3000: 2996: 2992: 2988: 2984: 2980: 2973: 2965: 2961: 2957: 2953: 2949: 2945: 2941: 2937: 2933: 2929: 2922: 2914: 2910: 2906: 2902: 2895: 2887: 2883: 2878: 2873: 2868: 2863: 2859: 2855: 2851: 2847: 2843: 2836: 2828: 2824: 2819: 2814: 2810: 2806: 2803:(2): 369–83. 2802: 2798: 2794: 2787: 2779: 2775: 2770: 2765: 2761: 2757: 2753: 2749: 2745: 2738: 2736: 2727: 2723: 2719: 2715: 2711: 2707: 2704:(3): 310–20. 2703: 2699: 2692: 2684: 2680: 2676: 2672: 2668: 2664: 2660: 2656: 2649: 2641: 2637: 2633: 2629: 2625: 2621: 2617: 2613: 2606: 2598: 2592: 2584: 2580: 2575: 2570: 2566: 2562: 2558: 2554: 2550: 2542: 2534: 2530: 2526: 2522: 2518: 2514: 2510: 2506: 2499: 2491: 2487: 2482: 2477: 2472: 2467: 2463: 2459: 2455: 2451: 2447: 2440: 2438: 2421: 2417: 2411: 2403: 2399: 2393: 2385: 2381: 2375: 2368: 2364: 2359: 2357: 2355: 2347: 2343: 2338: 2336: 2334: 2329: 2322: 2320: 2311: 2309: 2298: 2289: 2284:Antibody type 2281: 2278: 2275: 2272: 2269: 2261: 2254: 2248: 2243: 2234: 2232: 2222: 2219: 2209: 2201: 2199: 2188: 2180: 2172: 2164: 2156: 2152: 2150: 2145: 2143: 2133: 2129: 2127: 2123: 2119: 2115: 2110: 2107: 2104: 2097:HIV infection 2094: 2085: 2083: 2079: 2069: 2065: 2062: 2052: 2050: 2046: 2042: 2041:hematopoiesis 2035:Hematopoiesis 2032: 2030: 2026: 2017: 2014: 2011: 2006: 2005: 2003: 2002:P. falciparum 1998: 1993: 1991: 1987: 1982: 1980: 1976: 1971: 1969: 1965: 1961: 1960: 1954: 1952: 1948: 1944: 1940: 1936: 1932: 1928: 1924: 1920: 1916: 1912: 1907: 1905: 1901: 1897: 1896: 1891: 1887: 1883: 1882: 1877: 1873: 1869: 1859: 1857: 1847: 1844: 1837: 1833: 1830: 1827: 1823: 1819: 1815: 1811: 1807: 1803: 1799: 1795: 1791: 1787: 1783: 1779: 1776: 1773: 1769: 1768:Grande Comore 1765: 1762: 1759: 1755: 1751: 1747: 1744: 1740: 1737: 1733: 1730: 1726: 1725: 1720: 1716: 1712: 1711:South Andaman 1708: 1704: 1700: 1696: 1693: 1692:Basque people 1689: 1685: 1681: 1677: 1676: 1675: 1668: 1665: 1662: 1661: 1660: 1656: 1654: 1650: 1649:Black African 1646: 1642: 1638: 1628: 1626: 1625: 1619: 1616: 1614: 1610: 1605: 1603: 1599: 1594: 1592: 1587: 1582: 1578: 1573: 1570: 1566: 1564: 1559: 1555: 1551: 1544: 1540: 1538: 1534: 1532: 1528: 1526: 1522: 1520: 1516: 1515: 1514: 1509: 1505: 1501: 1499: 1495: 1493: 1489: 1488: 1487: 1484: 1482: 1477: 1474: 1470: 1467: 1463: 1459: 1455: 1451: 1450:erythroblasts 1447: 1446:reticulocytes 1442: 1433: 1430: 1427: 1425: 1424: 1419: 1418: 1412: 1408: 1404: 1402: 1401: 1396: 1395: 1390: 1389: 1384: 1383: 1379:(brown rat), 1378: 1377: 1373:(orangutan), 1372: 1371: 1366: 1365: 1360: 1359: 1353: 1351: 1345: 1343: 1339: 1334: 1332: 1328: 1324: 1320: 1316: 1312: 1308: 1303: 1301: 1297: 1293: 1289: 1285: 1281: 1277: 1273: 1269: 1265: 1261: 1257: 1253: 1249: 1245: 1241: 1237: 1233: 1232:aspartic acid 1229: 1225: 1220: 1218: 1217: 1211: 1209: 1205: 1201: 1197: 1193: 1189: 1179: 1175: 1173: 1169: 1165: 1161: 1157: 1152: 1150: 1146: 1142: 1131: 1129: 1128:Polymorphisms 1125: 1124: 1119: 1118: 1113: 1112: 1107: 1103: 1099: 1096: 1092: 1087: 1085: 1082: 1078: 1074: 1070: 1066: 1062: 1058: 1054: 1050: 1038: 1033: 1029: 1025: 1022: 1018: 1011: 1009: 1006: 1002: 998: 994: 991: 987: 983: 976: 974: 968: 964: 961: 955: 953: 949: 943: 939: 936: 932: 925: 923: 917: 913: 910: 904: 902: 898: 892: 888: 885: 883:RefSeq (mRNA) 881: 874: 873: 868: 864: 861: 855: 854: 849: 845: 842: 840: 836: 829: 828: 823: 819: 816: 810: 809: 804: 800: 797: 795: 791: 784: 783: 778: 774: 771: 765: 764: 759: 755: 752: 750: 746: 743: 740: 738: 735: 731: 728: 724: 720: 713: 709: 704: 698: 695: 693: 690: 688: 685: 683: 680: 678: 675: 673: 670: 669: 667: 664: 663: 657: 654: 652: 649: 647: 644: 642: 639: 637: 634: 632: 629: 628: 626: 623: 622: 616: 613: 611: 608: 606: 603: 601: 598: 596: 593: 591: 588: 586: 583: 582: 580: 577: 576: 573: 572:Gene ontology 569: 565: 553: 548: 545: 543: 539: 531: 526: 515: 511: 507: 503: 499: 495: 491: 487: 483: 479: 478: 475: 471: 466: 463: 453: 449: 445: 441: 437: 433: 429: 425: 421: 417: 416: 413: 409: 404: 401: 400: 397: 395: 391: 389: 388: 384: 383: 380: 378: 374: 370: 366: 362: 354: 349: 345: 341: 336: 326: 322: 315: 308: 302: 295: 287: 283: 279: 274: 270: 265: 261: 253: 248: 244: 240: 235: 225: 221: 214: 207: 201: 194: 190: 184: 180: 176: 171: 167: 162: 158: 154: 150: 146: 142: 138: 134: 130: 126: 122: 118: 110: 105: 98: 93: 88: 77: 75: 71: 65: 60: 57: 56: 52: 49: 42: 38: 33: 29: 25: 20: 9760: 8908: 8903: 8828: 8806: 8784: 8631: 8594: 8557: 8510: 8480: 8453: 8275: 8181: 8029: 7758: 7510: 7343: 7277:(5): 384–7. 7274: 7270: 7245: 7241: 7206: 7202: 7171: 7167: 7130: 7126: 7098: 7094: 7066:(3): 622–6. 7063: 7059: 7022: 7018: 6985: 6981: 6955: 6951: 6932: 6926: 6917: 6879: 6875: 6865: 6840: 6836: 6829: 6796: 6792: 6786: 6772:(1): 48–52. 6769: 6765: 6759: 6727:(1): 36–41. 6724: 6720: 6710: 6683: 6679: 6669: 6634: 6630: 6620: 6593: 6589: 6579: 6544: 6540: 6530: 6495: 6491: 6481: 6449:(3): 634–8. 6446: 6442: 6432: 6397: 6393: 6383: 6348: 6344: 6334: 6302:(1): 52–62. 6299: 6295: 6247: 6243: 6233: 6206: 6202: 6192: 6168:(3): 177–8. 6165: 6161: 6151: 6114: 6110: 6100: 6067: 6063: 6050: 6015: 6011: 6001: 5964: 5960: 5950: 5915: 5911: 5901: 5866: 5862: 5852: 5797: 5793: 5740: 5736: 5725: 5685:(1): 13851. 5682: 5678: 5668: 5631: 5627: 5617: 5576: 5572: 5562: 5517: 5513: 5503: 5470: 5466: 5460: 5425: 5422:J. Parasitol 5421: 5411: 5374: 5370: 5360: 5315: 5311: 5301: 5274: 5270: 5260: 5235: 5231: 5224: 5187: 5183: 5173: 5136: 5132: 5122: 5088:(6): e1192. 5085: 5081: 5071: 5026: 5022: 5011: 4984: 4980: 4920: 4916: 4906: 4884:(2): 133–6. 4881: 4877: 4871: 4828: 4824: 4814: 4797: 4793: 4787: 4754: 4750: 4744: 4719: 4715: 4709: 4687:(5): 193–6. 4684: 4680: 4674: 4652:(1): 17–22. 4649: 4645: 4639: 4606: 4602: 4595: 4568: 4564: 4554: 4521: 4517: 4511: 4494: 4490: 4484: 4451: 4448:Transfus Med 4447: 4441: 4408: 4404: 4398: 4365: 4361: 4355: 4338: 4334: 4324: 4302:(6): 302–4. 4299: 4295: 4289: 4262: 4259:Hum. Immunol 4258: 4224: 4216: 4184:(1): 101–8. 4181: 4178:Nat. Immunol 4177: 4167: 4134: 4130: 4123: 4098: 4094: 4088: 4053: 4049: 4039: 4009:(3): 260–8. 4006: 4002: 3995: 3968: 3965:Rheumatology 3964: 3954: 3919: 3915: 3908: 3881: 3877: 3867: 3842: 3838: 3832: 3805: 3801: 3791: 3758: 3754: 3748: 3723: 3719: 3713: 3678: 3674: 3664: 3642:(1): 137–9. 3639: 3635: 3629: 3602: 3598: 3588: 3561: 3557: 3547: 3506: 3502: 3496: 3488: 3455: 3451: 3445: 3437: 3410: 3406: 3396: 3369: 3365: 3355: 3320: 3316: 3306: 3271: 3267: 3257: 3222: 3218: 3208: 3173: 3169: 3159: 3126: 3122: 3078: 3075:Glycoconj. J 3074: 3064: 3031: 3027: 3021: 2986: 2982: 2972: 2931: 2927: 2921: 2907:(3): 230–6. 2904: 2900: 2894: 2849: 2845: 2835: 2800: 2796: 2786: 2751: 2747: 2701: 2697: 2691: 2661:(2): 224–8. 2658: 2654: 2648: 2615: 2611: 2605: 2591: 2556: 2552: 2541: 2511:(2): 224–8. 2508: 2504: 2498: 2453: 2449: 2426:September 9, 2424:. Retrieved 2419: 2416:"ACKR1 gene" 2410: 2401: 2392: 2383: 2374: 2317: 2304: 2295: 2287: 2279: 2276: 2273: 2270: 2267: 2258: 2228: 2215: 2207: 2194: 2186: 2178: 2170: 2162: 2153: 2146: 2139: 2136:Inflammation 2130: 2111: 2108: 2100: 2091: 2075: 2066: 2058: 2038: 2023: 2015: 2009: 2007: 2000: 1994: 1989: 1985: 1983: 1978: 1972: 1967: 1963: 1959:A. nancymaae 1957: 1955: 1950: 1934: 1922: 1910: 1908: 1903: 1893: 1885: 1879: 1875: 1865: 1853: 1845: 1841: 1728: 1722: 1672: 1657: 1645:West African 1634: 1622: 1620: 1617: 1606: 1595: 1574: 1567: 1547: 1512: 1485: 1478: 1454:erythrocytes 1443: 1439: 1431: 1428: 1423:Hepatocystis 1421: 1415: 1413: 1409: 1405: 1398: 1392: 1386: 1382:Mus musculus 1380: 1374: 1368: 1362: 1356: 1354: 1346: 1335: 1307:black people 1304: 1292:transversion 1238:in Fy-a and 1230:in Fy-a and 1221: 1214: 1212: 1200:glycoprotein 1192:chromosome 1 1185: 1176: 1153: 1137: 1121: 1115: 1109: 1104:for several 1095:glycosylated 1088: 1080: 1072: 1068: 1064: 1060: 1056: 1052: 1048: 1047: 970: 948:NP_001116423 945: 919: 901:NM_001122951 894: 870: 851: 825: 806: 780: 761: 741: 736: 516:hypothalamus 438:tibial nerve 392: 385: 351:173,161,317 338:173,159,453 250:159,206,500 237:159,203,307 112:External IDs 67: 9709:Blood types 9608:Coombs test 9444:Whole blood 6988:(1): 76–8. 6882:(2): 63–6. 6793:Transfusion 6637:(1): 50–1. 6162:Cancer Cell 5628:PLOS Pathog 4571:(1): 10–4. 3317:J. Exp. Med 3123:Transfusion 2983:Transfusion 2698:Transfusion 1890:erythrocyte 1881:P. knowlesi 1794:Afroasiatic 1790:Nile Valley 1637:erythrocyte 1624:P. knowlesi 1577:endothelial 1469:capillaries 1391:(opossum), 1256:transitions 1160:hemophiliac 1145:thalassemia 492:bone marrow 434:pericardium 90:Identifiers 9935:Categories 9521:Blood bank 7393:(see also 7325:Duffy gene 7271:J. Nephrol 7019:Hum. Genet 6982:Hum. Genet 5377:(1): 430. 4831:(4): 266. 4825:Nat Commun 3878:Kidney Int 3802:Kidney Int 2505:Nat. Genet 2369:, May 2017 2348:, May 2017 2325:References 2114:Leukopenia 2082:metastasis 2061:neutrophil 2043:. Indeed, 1939:Mauritania 1915:Madagascar 1906:invasion. 1874:parasites 1856:Plasmodium 1810:Mauritania 1806:Nouakchott 1758:She people 1613:chemotaxis 1602:leukocytes 1591:neutrophil 1581:epithelial 1481:asparagine 1462:cerebellum 1397:(cow) and 1394:Bos taurus 1325:erythroid 1315:nucleotide 1224:amino acid 1208:phenotypes 1172:phenotypes 1106:chemokines 1071:luster of 446:ectocervix 396:(ortholog) 133:HomoloGene 9726:Augustine 9670:reaction 9668:Hemolytic 9557:Apheresis 9449:Platelets 5842:Rigby A. 5609:206544569 4603:Hum. Biol 4518:Hum. Biol 4362:Hum. Biol 4003:J. Pathol 3924:CiteSeerX 3755:J. Pathol 3539:206544569 3298:250366123 2655:Nat Genet 2183:Pregnancy 2175:Pneumonia 1895:P. yoelii 1798:Tunisians 1627:to DARC. 1586:knock out 1529:ENA-78 - 1385:(mouse), 1342:thymidine 1288:Threonine 1280:Adenosine 1264:Threonine 1240:adenosine 1234:in Fy-b ( 973:NP_034175 952:NP_002027 922:NM_010045 897:NM_002036 727:Orthologs 418:vena cava 141:GeneCards 9961:HIV/AIDS 9851:Lutheran 9756:Dombrock 9541:ISBT 128 7387:Proteins 7283:11730271 7155:25725619 7047:22363912 6898:19927622 6857:20347396 6821:40367918 6813:18248572 6778:18344944 6751:20596779 6702:12533524 6661:20469787 6653:19206111 6612:19608592 6571:18576313 6522:26366554 6473:23017229 6443:Cytokine 6424:21507922 6375:19620399 6326:18621010 6274:23613539 6266:19187081 6225:16785997 6203:Oncogene 6184:16959609 6143:30972057 6092:58010066 6084:30647433 6042:35994632 5993:19180233 5942:32959868 5893:35994632 5824:28553950 5767:18827265 5717:30218021 5660:23853575 5601:23224555 5554:22123959 5495:35436028 5487:20162434 5452:19799492 5403:23259672 5371:Malar. J 5352:21603649 5312:PLOS ONE 5293:19803728 5252:17604067 5216:18093292 5184:Malar. J 5165:22050867 5133:Malar. J 5114:21713024 5063:20231434 5003:17038676 4957:23028857 4917:PLOS ONE 4898:21840761 4863:21468018 4779:27486979 4771:18608113 4701:17360237 4666:20558108 4631:36391602 4623:15754970 4587:15783300 4546:25812715 4538:11446431 4476:19301986 4468:15943709 4425:16566771 4390:46134067 4382:16596943 4347:16110438 4281:10439320 4208:19060902 4159:11847880 4151:18230715 4115:17073738 4080:22739165 4072:12698093 4031:19284627 4023:15887283 3987:15572394 3946:11228176 3900:11012889 3859:16054417 3824:10201015 3775:12081195 3740:10961863 3705:12734373 3656:12646177 3531:23224555 3290:35803222 3200:12262317 3151:46112984 3143:10960522 3105:22246380 3056:17624523 3048:22395823 3013:22082243 2956:19553936 2913:19724088 2886:10570183 2827:11753822 2778:10762551 2726:43747569 2718:10738032 2583:28698207 2365:– 2344:– 2198:Jamaican 2126:cytokine 2120:than in 2010:P. vivax 1990:P. vivax 1979:P. vivax 1968:P. vivax 1964:P. vivax 1951:P. vivax 1935:P. vivax 1923:P. vivax 1911:P. vivax 1904:P. vivax 1886:P. vivax 1876:P. vivax 1872:malarial 1868:receptor 1788:and the 1772:Ngazidja 1756:and the 1736:Yemenite 1338:cytosine 1331:mutation 1319:promoter 1272:Cysteine 1268:Arginine 1260:Cytosine 1252:GATA box 1248:promoter 1188:receptor 1164:antibody 1102:receptor 1021:Wikidata 706:Sources: 656:membrane 641:endosome 9890:Scianna 9776:Gerbich 9679:delayed 9550:Methods 9195:301–350 8989:251–300 8941:CD240CE 8738:201–250 8422:151–200 8145:101–150 7350:PDBe-KB 7340:UniProt 7262:9921412 7233:7873621 7225:9886340 7190:9746760 7147:9731074 7117:9195930 7082:7833467 7039:7705836 7010:7905017 7002:2892777 6972:8542025 6742:3017736 6562:2821686 6513:4627508 6464:3501981 6415:3115278 6366:2927046 6317:2562426 6134:6443851 6117:: 551. 6033:9881043 5984:2628742 5933:7906776 5884:9881043 5815:5480598 5758:2582596 5708:6138695 5687:Bibcode 5651:3681752 5581:Bibcode 5573:Science 5545:3250126 5522:Bibcode 5443:2883003 5394:3544589 5343:3094453 5320:Bibcode 5207:2244634 5190:: 167. 5156:3228859 5139:: 336. 5105:3119644 5054:2851935 5031:Bibcode 4948:3448599 4925:Bibcode 4854:3074097 4833:Bibcode 4806:3769126 4736:7015888 4503:7346047 4433:7461139 4199:3205989 3783:2948161 3696:4357319 3621:8132497 3580:7592830 3511:Bibcode 3503:Science 3480:7689250 3460:Bibcode 3452:Science 3429:7517400 3388:8132497 3347:7699323 3338:2191961 3249:8083383 3192:9058825 3096:3311851 3004:3374024 2964:4430340 2936:Bibcode 2854:Bibcode 2769:1378024 2683:7125832 2675:7663520 2640:4265241 2620:Bibcode 2574:5600141 2533:7125832 2525:7663520 2490:8248172 2458:Bibcode 2367:Ensembl 2346:Ensembl 2147:In the 1900:epitope 1862:Malaria 1822:Soninke 1801:region. 1782:Maghreb 1780:In the 1750:Chinese 1748:In the 1734:In the 1719:malaria 1707:Jarawas 1703:Nicobar 1699:Andaman 1558:protein 1473:venules 1466:thyroid 1460:of the 1403:(dog). 1296:Alanine 1284:Alanine 1276:Guanine 1236:guanine 1228:glycine 1204:alleles 1156:antigen 1134:History 1077:protein 839:UniProt 794:Ensembl 733:Species 712:QuickGO 371:pattern 129:1097689 97:Aliases 9801:Indian 9746:Cromer 9741:Colton 9466:Plasma 9202:CD300A 9161:CDw293 8946:CD240D 8807:CD213a 8785:CDw210 8750:CD202b 8724:CDw199 8719:CDw198 8373:CD140b 7805:51–100 7345:Q16570 7304:(MeSH) 7281: 7260: 7231: 7223: 7188: 7153: 7145: 7115: 7080: 7045: 7037: 7008: 7000: 6970: 6896: 6855: 6819: 6811: 6776: 6749: 6739: 6700: 6659: 6651: 6610: 6569: 6559: 6520: 6510: 6471: 6461: 6422: 6412: 6373: 6363: 6324: 6314: 6272: 6264: 6223: 6182: 6141: 6131: 6090: 6082: 6040: 6030: 5991: 5981: 5940: 5930: 5891: 5881: 5822: 5812: 5765: 5755: 5715: 5705: 5658: 5648: 5607: 5599: 5552: 5542: 5493: 5485: 5450: 5440: 5401: 5391: 5350: 5340: 5291: 5250: 5214: 5204: 5163: 5153: 5112: 5102: 5061: 5051: 5001: 4955: 4945: 4896: 4861: 4851: 4804: 4777: 4769: 4734: 4699: 4664: 4629: 4621: 4585: 4544: 4536: 4501: 4474: 4466: 4431: 4423: 4388: 4380: 4345: 4316:778616 4314: 4279: 4233: 4206: 4196: 4157: 4149: 4113: 4078: 4070: 4029: 4021: 3985: 3944: 3926: 3898: 3857: 3822: 3781: 3773: 3738: 3703: 3693: 3654: 3619: 3578: 3537: 3529: 3478: 3427: 3386: 3345: 3335: 3296: 3288: 3247: 3240:295143 3237: 3198: 3190: 3149: 3141: 3103: 3093: 3054: 3046: 3011: 3001: 2962: 2954: 2928:Nature 2911: 2884: 2874: 2825: 2818:419988 2815: 2776: 2766: 2724: 2716: 2681: 2673: 2638: 2612:Nature 2581: 2571: 2531: 2523: 2488: 2478: 2118:whites 2072:Cancer 2025:Asthma 2020:Asthma 1947:Brazil 1927:Angola 1898:. The 1818:Poular 1792:, the 1340:-> 1311:allele 1300:Serine 1274:) and 1063:) or 1007:search 1005:PubMed 872:Q9QUI6 853:Q16570 749:Entrez 542:BioGPS 229:1q23.2 121:613665 9920:Other 9846:Lewis 9836:Knops 9816:KANNO 9761:Duffy 9751:Diego 9674:acute 9589:Tests 9382:CD350 9377:CD349 9372:CD344 9367:CD340 9362:CD339 9357:CD338 9352:CD337 9347:CD336 9342:CD335 9337:CD334 9332:CD333 9327:CD332 9322:CD331 9317:CD329 9312:CD328 9307:CD327 9302:CD326 9297:CD325 9292:CD324 9287:CD322 9282:CD321 9277:CD320 9272:CD318 9267:CD317 9262:CD316 9257:CD315 9252:CD314 9247:CD312 9242:CD309 9237:CD307 9232:CD306 9227:CD305 9222:CD304 9217:CD303 9212:CD302 9207:CD301 9186:CD299 9181:CD298 9176:CD297 9171:CD295 9166:CD294 9156:CD292 9151:CD290 9146:CD289 9141:CD288 9136:CD286 9131:CD284 9126:CD283 9121:CD282 9116:CD281 9111:CD280 9106:CD279 9101:CD278 9096:CD276 9091:CD275 9086:CD274 9081:CD273 9076:CD272 9071:CD271 9066:CD269 9061:CD268 9056:CD267 9051:CD266 9046:CD265 9041:CD264 9036:CD263 9031:CD262 9026:CD261 9021:CD258 9016:CD257 9011:CD256 9006:CD254 9001:CD253 8996:CD252 8980:CD249 8975:CD248 8971:CD247 8966:CD246 8961:CD244 8956:CD243 8951:CD241 8936:CD239 8931:CD238 8926:CD236 8909:CD235 8904:CD234 8899:CD233 8894:CD230 8889:CD229 8884:CD228 8879:CD227 8874:CD226 8869:CD225 8864:CD224 8859:CD223 8854:CD222 8849:CD221 8844:CD220 8829:CD218 8824:CD217 8802:CD212 8780:CD209 8775:CD208 8770:CD207 8765:CD206 8760:CD205 8755:CD204 8745:CD201 8729:CD200 8714:CD197 8709:CD196 8704:CD195 8699:CD194 8694:CD193 8689:CD192 8684:CD191 8679:CD186 8674:CD185 8669:CD184 8664:CD183 8659:CD182 8654:CD181 8649:CD180 8632:CD179 8627:CD178 8622:CD177 8617:CD174 8595:CD172 8590:CD171 8585:CD170 8580:CD169 8575:CD168 8558:CD167 8553:CD166 8548:CD164 8543:CD163 8538:CD162 8533:CD161 8528:CD160 8511:CD159 8481:CD158 8476:CD157 8454:CD156 8449:CD155 8444:CD154 8439:CD153 8434:CD152 8429:CD151 8413:CD150 8408:CD148 8403:CD147 8398:CD146 8393:CD144 8388:CD143 8383:CD142 8378:CD141 8368:CD138 8363:CD137 8358:CD136 8353:CD135 8348:CD134 8343:CD133 8338:CD132 8333:CD131 8328:CD130 8323:CD129 8318:CD127 8313:CD126 8308:CD125 8303:CD124 8298:CD123 8293:CD122 8276:CD121 8259:CD120 8254:CD119 8249:CD118 8244:CD117 8239:CD116 8234:CD115 8229:CD114 8224:CD113 8219:CD112 8214:CD111 8209:CD110 8204:CD109 8199:CD108 8182:CD107 8177:CD106 8172:CD105 8167:CD104 8162:CD103 8157:CD102 8152:CD101 8136:CD100 7312:BGMUT 7308:Duffy 7229:S2CID 7168:Blood 7151:S2CID 7127:Blood 7060:Blood 7043:S2CID 7006:S2CID 6817:S2CID 6657:S2CID 6345:Blood 6270:S2CID 6088:S2CID 6060:(PDF) 5605:S2CID 5491:S2CID 4775:S2CID 4627:S2CID 4542:S2CID 4472:S2CID 4429:S2CID 4386:S2CID 4155:S2CID 4076:S2CID 4027:S2CID 3779:S2CID 3720:Blood 3535:S2CID 3294:S2CID 3196:S2CID 3147:S2CID 3052:S2CID 2960:S2CID 2877:24175 2722:S2CID 2679:S2CID 2636:S2CID 2553:Blood 2529:S2CID 2481:47864 1997:CXCL4 1943:Kenya 1826:Wolof 1814:Moors 1684:White 1680:codon 1609:CD195 1543:CXCL8 1537:CXCL7 1531:CXCL5 1525:CXCL4 1519:CXCL1 1508:CXCL2 1504:CXCL1 1323:GATA1 1216:ACKR1 1196:exons 1168:serum 1081:ACKR1 1065:CD234 782:13349 742:Mouse 737:Human 708:Amigo 394:Mouse 387:Human 334:Start 269:Mouse 233:Start 166:Human 145:ACKR1 137:48067 104:ACKR1 22:ACKR1 9900:T-Tn 9885:RHAG 9883:and 9876:Raph 9871:P1PK 9831:Kidd 9821:Kell 9786:GLOB 9771:FORS 9731:CD59 9476:PF24 9426:and 8131:CD99 8126:CD98 8121:CD97 8116:CD96 8111:CD95 8106:CD94 8101:CD93 8096:CD92 8092:CD91 8087:CD90 8082:CD89 8077:CD88 8072:CD87 8067:CD86 8030:CD85 8025:CD84 8020:CD83 8015:CD82 8010:CD81 8005:CD80 7988:CD79 7983:CD78 7978:CD74 7973:CD73 7968:CD72 7963:CD71 7958:CD70 7953:CD69 7948:CD68 7911:CD66 7889:CD64 7884:CD63 7862:CD62 7857:CD61 7852:CD59 7847:CD58 7842:CD57 7837:CD56 7832:CD55 7827:CD54 7822:CD53 7817:CD52 7812:CD51 7796:CD50 7759:CD49 7754:CD48 7749:CD47 7744:CD46 7739:CD45 7734:CD44 7729:CD43 7702:CD42 7697:CD41 7692:CD40 7687:CD39 7682:CD38 7677:CD37 7672:CD36 7667:CD35 7662:CD34 7657:CD33 7640:CD32 7635:CD31 7630:CD30 7625:CD29 7620:CD28 7615:CD27 7610:CD26 7605:CD25 7600:CD24 7595:CD23 7590:CD22 7585:CD21 7580:CD20 7575:CD19 7570:CD18 7553:CD16 7548:CD15 7543:CD14 7538:CD13 7511:CD11 7506:CD10 7403:1–50 7338:for 7316:NCBI 7279:PMID 7258:PMID 7221:PMID 7186:PMID 7143:PMID 7113:PMID 7078:PMID 7035:PMID 6998:PMID 6968:PMID 6894:PMID 6853:PMID 6809:PMID 6774:PMID 6747:PMID 6698:PMID 6649:PMID 6608:PMID 6567:PMID 6518:PMID 6469:PMID 6420:PMID 6371:PMID 6322:PMID 6262:PMID 6221:PMID 6180:PMID 6139:PMID 6080:PMID 6038:PMID 5989:PMID 5938:PMID 5889:PMID 5820:PMID 5763:PMID 5713:PMID 5656:PMID 5597:PMID 5550:PMID 5483:PMID 5448:PMID 5399:PMID 5348:PMID 5289:PMID 5248:PMID 5212:PMID 5161:PMID 5110:PMID 5059:PMID 4999:PMID 4953:PMID 4894:PMID 4859:PMID 4802:PMID 4767:PMID 4732:PMID 4697:PMID 4662:PMID 4619:PMID 4583:PMID 4534:PMID 4499:PMID 4464:PMID 4421:PMID 4378:PMID 4343:PMID 4312:PMID 4277:PMID 4231:ISBN 4204:PMID 4147:PMID 4111:PMID 4068:PMID 4019:PMID 3983:PMID 3942:PMID 3896:PMID 3855:PMID 3820:PMID 3771:PMID 3736:PMID 3701:PMID 3652:PMID 3617:PMID 3576:PMID 3527:PMID 3476:PMID 3425:PMID 3384:PMID 3343:PMID 3286:PMID 3245:PMID 3188:PMID 3139:PMID 3101:PMID 3044:PMID 3009:PMID 2952:PMID 2909:PMID 2882:PMID 2823:PMID 2774:PMID 2714:PMID 2671:PMID 2579:PMID 2521:PMID 2486:PMID 2428:2020 2078:KAI1 1929:and 1878:and 1836:Iran 1824:and 1739:Jews 1701:and 1697:The 1598:CD82 1498:CCL5 1492:CCL2 1147:and 1084:gene 1053:DARC 763:2532 377:Bgee 325:Band 286:Chr. 224:Band 183:Chr. 117:OMIM 74:4NUV 70:4NUU 51:RCSB 48:PDBe 9905:Vel 9895:Sid 9861:MNS 9841:Lan 9811:JMH 9781:GIL 9714:ABO 7501:CD9 7489:CD8 7484:CD7 7479:CD6 7474:CD5 7469:CD4 7447:CD3 7442:CD2 7415:a-c 7410:CD1 7336:PDB 7320:NIH 7310:at 7250:doi 7211:doi 7207:103 7176:doi 7135:doi 7103:doi 7099:272 7068:doi 7027:doi 6990:doi 6960:doi 6884:doi 6845:doi 6841:136 6801:doi 6737:PMC 6729:doi 6688:doi 6639:doi 6598:doi 6557:PMC 6549:doi 6508:PMC 6500:doi 6459:PMC 6451:doi 6410:PMC 6402:doi 6361:PMC 6353:doi 6349:114 6312:PMC 6304:doi 6252:doi 6211:doi 6170:doi 6129:PMC 6119:doi 6072:doi 6028:PMC 6020:doi 5979:PMC 5969:doi 5928:PMC 5920:doi 5879:PMC 5871:doi 5810:PMC 5802:doi 5753:PMC 5745:doi 5741:178 5703:PMC 5695:doi 5646:PMC 5636:doi 5589:doi 5577:338 5540:PMC 5530:doi 5518:108 5475:doi 5471:106 5438:PMC 5430:doi 5389:PMC 5379:doi 5338:PMC 5328:doi 5279:doi 5275:200 5240:doi 5236:101 5202:PMC 5192:doi 5151:PMC 5141:doi 5100:PMC 5090:doi 5049:PMC 5039:doi 5027:107 4989:doi 4943:PMC 4933:doi 4886:doi 4849:PMC 4841:doi 4759:doi 4724:doi 4689:doi 4654:doi 4611:doi 4573:doi 4526:doi 4456:doi 4413:doi 4370:doi 4304:doi 4300:295 4267:doi 4194:PMC 4186:doi 4139:doi 4103:doi 4058:doi 4011:doi 4007:206 3973:doi 3934:doi 3886:doi 3847:doi 3810:doi 3763:doi 3759:197 3728:doi 3691:PMC 3683:doi 3679:170 3644:doi 3640:303 3607:doi 3603:269 3566:doi 3562:270 3519:doi 3507:338 3468:doi 3456:261 3415:doi 3411:269 3374:doi 3370:269 3333:PMC 3325:doi 3321:181 3276:doi 3235:PMC 3227:doi 3178:doi 3174:158 3131:doi 3091:PMC 3083:doi 3036:doi 2999:PMC 2991:doi 2944:doi 2932:460 2872:PMC 2862:doi 2813:PMC 2805:doi 2764:PMC 2756:doi 2706:doi 2663:doi 2628:doi 2616:165 2569:PMC 2561:doi 2557:130 2513:doi 2476:PMC 2466:doi 2103:HIV 2029:IgE 1921:of 1834:In 1804:In 1766:In 1754:Han 1286:100 1278:298 1262:265 550:n/a 347:End 246:End 149:OMA 125:MGI 41:PDB 9937:: 9915:Yt 9910:Xg 9881:Rh 9866:OK 9856:LW 9825:Xk 9806:JR 9796:Ii 9791:Hh 9766:Er 9567:, 9563:, 8973:- 8094:- 7435:1E 7430:1D 7425:1B 7420:1A 7389:: 7342:: 7318:, 7275:14 7273:. 7256:. 7246:52 7244:. 7227:. 7219:. 7205:. 7201:. 7184:. 7172:92 7170:. 7166:. 7149:. 7141:. 7131:92 7129:. 7111:. 7097:. 7093:. 7076:. 7064:85 7062:. 7058:. 7041:. 7033:. 7023:95 7021:. 7004:. 6996:. 6986:78 6984:. 6966:. 6954:. 6906:^ 6892:. 6880:25 6878:. 6874:. 6851:. 6839:. 6815:. 6807:. 6797:48 6795:. 6770:13 6768:. 6745:. 6735:. 6725:13 6723:. 6719:. 6696:. 6684:51 6682:. 6678:. 6655:. 6647:. 6635:27 6633:. 6629:. 6606:. 6594:35 6592:. 6588:. 6565:. 6555:. 6545:58 6543:. 6539:. 6516:. 6506:. 6496:47 6494:. 6490:. 6467:. 6457:. 6447:60 6445:. 6441:. 6418:. 6408:. 6398:52 6396:. 6392:. 6369:. 6359:. 6347:. 6343:. 6320:. 6310:. 6298:. 6294:. 6282:^ 6268:. 6260:. 6246:. 6242:. 6219:. 6207:25 6205:. 6201:. 6178:. 6166:10 6164:. 6160:. 6137:. 6127:. 6115:10 6113:. 6109:. 6086:. 6078:. 6068:24 6066:. 6062:. 6036:. 6026:. 6014:. 6010:. 5987:. 5977:. 5963:. 5959:. 5936:. 5926:. 5916:29 5914:. 5910:. 5887:. 5877:. 5865:. 5861:. 5832:^ 5818:. 5808:. 5798:18 5796:. 5792:. 5775:^ 5761:. 5751:. 5739:. 5735:. 5711:. 5701:. 5693:. 5681:. 5677:. 5654:. 5644:. 5630:. 5626:. 5603:. 5595:. 5587:. 5575:. 5571:. 5548:. 5538:. 5528:. 5516:. 5512:. 5489:. 5481:. 5469:. 5446:. 5436:. 5426:96 5424:. 5420:. 5397:. 5387:. 5375:11 5373:. 5369:. 5346:. 5336:. 5326:. 5314:. 5310:. 5287:. 5273:. 5269:. 5246:. 5234:. 5210:. 5200:. 5186:. 5182:. 5159:. 5149:. 5137:10 5135:. 5131:. 5108:. 5098:. 5084:. 5080:. 5057:. 5047:. 5037:. 5025:. 5021:. 4997:. 4985:75 4983:. 4979:. 4965:^ 4951:. 4941:. 4931:. 4919:. 4915:. 4892:. 4882:45 4880:. 4857:. 4847:. 4839:. 4827:. 4823:. 4798:79 4773:. 4765:. 4755:35 4753:. 4730:. 4720:30 4718:. 4695:. 4685:23 4683:. 4660:. 4650:43 4648:. 4625:. 4617:. 4607:76 4605:. 4581:. 4569:21 4567:. 4563:. 4540:. 4532:. 4522:73 4520:. 4493:. 4470:. 4462:. 4452:15 4450:. 4427:. 4419:. 4409:51 4407:. 4384:. 4376:. 4366:77 4364:. 4337:. 4333:. 4310:. 4298:. 4275:. 4263:60 4261:. 4257:. 4245:^ 4202:. 4192:. 4182:10 4180:. 4176:. 4153:. 4145:. 4135:73 4133:. 4109:. 4099:34 4097:. 4074:. 4066:. 4054:75 4052:. 4048:. 4025:. 4017:. 4005:. 3981:. 3969:44 3967:. 3963:. 3940:. 3932:. 3920:37 3918:. 3894:. 3882:58 3880:. 3876:. 3853:. 3843:16 3841:. 3818:. 3806:55 3804:. 3800:. 3777:. 3769:. 3757:. 3734:. 3724:96 3722:. 3699:. 3689:. 3677:. 3673:. 3650:. 3638:. 3615:. 3601:. 3597:. 3574:. 3560:. 3556:. 3533:. 3525:. 3517:. 3505:. 3501:. 3474:. 3466:. 3454:. 3450:. 3423:. 3409:. 3405:. 3382:. 3368:. 3364:. 3341:. 3331:. 3319:. 3315:. 3292:. 3284:. 3272:29 3270:. 3266:. 3243:. 3233:. 3223:94 3221:. 3217:. 3194:. 3186:. 3172:. 3168:. 3145:. 3137:. 3127:40 3125:. 3113:^ 3099:. 3089:. 3079:29 3077:. 3073:. 3050:. 3042:. 3032:64 3030:. 3007:. 2997:. 2987:52 2985:. 2981:. 2958:. 2950:. 2942:. 2930:. 2905:46 2903:. 2880:. 2870:. 2860:. 2850:96 2848:. 2844:. 2821:. 2811:. 2801:70 2799:. 2795:. 2772:. 2762:. 2752:66 2750:. 2746:. 2734:^ 2720:. 2712:. 2702:40 2700:. 2677:. 2669:. 2659:10 2657:. 2634:. 2626:. 2614:. 2577:. 2567:. 2555:. 2551:. 2527:. 2519:. 2509:10 2507:. 2484:. 2474:. 2464:. 2454:90 2452:. 2448:. 2436:^ 2418:. 2400:. 2382:. 2353:^ 2332:^ 1820:, 1808:, 1784:, 1565:. 1426:. 1333:. 1298:49 1270:89 1258:: 1219:. 1151:. 1143:, 1126:. 1114:, 1086:. 1061:FY 710:/ 353:bp 340:bp 252:bp 239:bp 147:; 143:: 139:; 135:: 131:; 127:: 123:; 119:: 72:, 9827:) 9823:( 9571:) 9559:( 9416:e 9409:t 9402:v 8919:b 8914:a 8840:) 8838:b 8833:a 8831:( 8817:2 8812:1 8795:b 8790:a 8642:b 8637:a 8610:g 8605:b 8600:a 8568:b 8563:a 8521:c 8516:a 8507:) 8505:k 8500:i 8495:e 8490:d 8485:a 8483:( 8469:c 8464:b 8459:a 8286:b 8281:a 8269:b 8264:a 8192:b 8187:a 8060:k 8055:j 8050:h 8045:e 8040:d 8035:a 7998:b 7993:a 7941:f 7936:e 7931:d 7926:c 7921:b 7916:a 7904:C 7899:B 7894:A 7877:P 7872:L 7867:E 7789:f 7784:e 7779:d 7774:c 7769:b 7764:a 7722:d 7717:c 7712:b 7707:a 7650:B 7645:A 7563:B 7558:A 7531:d 7526:c 7521:b 7516:a 7494:a 7462:ε 7457:δ 7452:γ 7397:) 7379:e 7372:t 7365:v 7352:. 7285:. 7264:. 7252:: 7235:. 7213:: 7192:. 7178:: 7157:. 7137:: 7119:. 7105:: 7084:. 7070:: 7049:. 7029:: 7012:. 6992:: 6974:. 6962:: 6956:2 6900:. 6886:: 6859:. 6847:: 6823:. 6803:: 6780:. 6753:. 6731:: 6704:. 6690:: 6663:. 6641:: 6614:. 6600:: 6573:. 6551:: 6524:. 6502:: 6475:. 6453:: 6426:. 6404:: 6377:. 6355:: 6328:. 6306:: 6300:4 6276:. 6254:: 6248:7 6227:. 6213:: 6186:. 6172:: 6145:. 6121:: 6094:. 6074:: 6044:. 6022:: 6016:7 5995:. 5971:: 5965:5 5944:. 5922:: 5895:. 5873:: 5867:7 5846:. 5826:. 5804:: 5769:. 5747:: 5719:. 5697:: 5689:: 5683:8 5662:. 5638:: 5632:9 5611:. 5591:: 5583:: 5556:. 5532:: 5524:: 5497:. 5477:: 5454:. 5432:: 5405:. 5381:: 5354:. 5330:: 5322:: 5316:6 5295:. 5281:: 5254:. 5242:: 5218:. 5194:: 5188:6 5167:. 5143:: 5116:. 5092:: 5086:5 5065:. 5041:: 5033:: 5005:. 4991:: 4959:. 4935:: 4927:: 4921:7 4900:. 4888:: 4865:. 4843:: 4835:: 4829:2 4808:. 4781:. 4761:: 4738:. 4726:: 4703:. 4691:: 4668:. 4656:: 4633:. 4613:: 4589:. 4575:: 4548:. 4528:: 4505:. 4495:4 4478:. 4458:: 4435:. 4415:: 4392:. 4372:: 4349:. 4339:4 4318:. 4306:: 4283:. 4269:: 4239:. 4210:. 4188:: 4161:. 4141:: 4117:. 4105:: 4082:. 4060:: 4033:. 4013:: 3989:. 3975:: 3948:. 3936:: 3902:. 3888:: 3861:. 3849:: 3826:. 3812:: 3785:. 3765:: 3742:. 3730:: 3707:. 3685:: 3658:. 3646:: 3623:. 3609:: 3582:. 3568:: 3541:. 3521:: 3513:: 3499:" 3482:. 3470:: 3462:: 3431:. 3417:: 3390:. 3376:: 3349:. 3327:: 3300:. 3278:: 3251:. 3229:: 3202:. 3180:: 3153:. 3133:: 3107:. 3085:: 3058:. 3038:: 3015:. 2993:: 2966:. 2946:: 2938:: 2915:. 2888:. 2864:: 2856:: 2829:. 2807:: 2780:. 2758:: 2728:. 2708:: 2685:. 2665:: 2642:. 2630:: 2622:: 2599:. 2585:. 2563:: 2535:. 2515:: 2492:. 2468:: 2460:: 2430:. 2404:. 2386:. 2004:. 1506:/ 1282:( 1266:( 1073:D 1069:C 1067:( 1059:( 1051:( 271:) 168:) 151::

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.

Knowledge

Duffy antigen system

Index