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Cutibacterium acnes

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are related to treating acne-related issues. This issue often develops during hormonal periods; however, it is also apparent through early adulthood. There are no quantitative differences between C. acnes of the skin of patients with acne, but the C. acnes phylogenetic groups display distinct genetic and phenotypic characteristics. C. acnes
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by which salicylic acid (SA) treats acne vulgaris. A study finds that SA suppresses the AMPK/SREBP1 (AMP-activated protein kinase)(AMPK/SREBP1 pathway is a signaling pathway involved in the regulation of lipid metabolism in sebocytes, which are the cells responsible for producing sebum in the skin)
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infection. Cutibacterium acnes is one of the most common and universal skin diseases, affecting more than 45 million individuals in the United States. It is one of the most prominent skin diseases, affecting more than 45 million individuals yearly within the country. 20% of all dermatologist visits
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In addition to contributing to skin inflammation and acne lesions, an imbalance in these bacteria may also impair the skin's ability to heal and regenerate, leading to prolonged and more severe acne outbreaks. This disruption can also affect the skin's overall microbiome diversity, potentially
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bacteria secrete many proteins, including several digestive enzymes. These enzymes are involved in the digestion of sebum and the acquisition of other nutrients. They can also destabilize the layers of cells that form the walls of the follicle. The cellular damage, metabolic byproducts and
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Ross JI, Snelling AM, Eady EA, Cove JH, Cunliffe WJ, Leyden JJ, et al. (February 2001). "Phenotypic and genotypic characterization of antibiotic-resistant Propionibacterium acnes isolated from acne patients attending dermatology clinics in Europe, the U.S.A., Japan and Australia".
970:"The natural history of cutaneous propionibacteria, and reclassification of selected species within the genus Propionibacterium to the proposed novel genera Acidipropionibacterium gen. nov., Cutibacterium gen. nov. and Pseudopropionibacterium gen. nov" 452:
starts to colonize on the skin around 1 to 3 years prior to puberty and grows exponentially during this time. This is why so many teens and young adults struggle with acne. Prescriptions to treat acne are often antibiotics. However, with the rise of
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that cause these infections of otherwise sterile tissues (prior to medical procedures), however, are the same subspecies found on the skin of individuals who do not have acne-prone skin, so are likely local contaminants. Moderate to severe
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Coates P, Vyakrnam S, Eady EA, Jones CE, Cove JH, Cunliffe WJ (May 2002). "Prevalence of antibiotic-resistant propionibacteria on the skin of acne patients: 10-year surveillance data and snapshot distribution study".
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increasing susceptibility to other skin conditions such as eczema or rosacea. Investigating the dynamics of this relationship may offer insights into novel therapeutic approaches for managing various skin disorders.
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Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit, which includes the hair follicle, hair shaft, and sebaceous gland and about 650 million people are affected globally by this disease.
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Haidar R., Najjar M., Boghossian A.D., Tabbarah Z., "Propionibacterium acnes causing delayed postoperative spine infection: Review." Scandinavian Journal of Infectious Diseases. 42 (6-7) (pp 405-411), 2010
824:. These results suggest that SA has a multifaceted approach in treating acne vulgaris by targeting several key factors that contribute to its development. The minimum inhibitory concentration for SA is 811:
is a naturally occurring substance derived from plants (white willow bark and wintergreen leaves) used to promote exfoliation of the skin in order to treat acne. Additionally, research investigates the
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Fu Y, Zu Y, Chen L, Efferth T, Liang H, Liu Z, Liu W (October 2007). "Investigation of antibacterial activity of rosemary essential oil against Propionibacterium acnes with atomic force microscopy".
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Togsverd-Bo K, Wiegell SR, Wulf HC, Haedersdal M (February 2009). "Short and limited effect of long-pulsed dye laser alone and in combination with photodynamic therapy for inflammatory rosacea".
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Hiramatsu J, Kataoka M, Nakata Y, Okazaki K, Tada S, Tanimoto M, Eishi Y (October 2003). "Propionibacterium acnes DNA detected in bronchoalveolar lavage cells from patients with sarcoidosis".
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have a symbiotic relationship. Both bacteria exist on the normal flora of the skin and a disrupt in balance of these bacteria on the skin can result in acne or other bacterial infection.
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Raman A, Weir U, Bloomfield SF (October 1995). "Antimicrobial effects of tea-tree oil and its major components on Staphylococcus aureus, Staph. epidermidis and Propionibacterium acnes".
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Brüggemann H, Henne A, Hoster F, Liesegang H, Wiezer A, Strittmatter A, et al. (July 2004). "The complete genome sequence of Propionibacterium acnes, a commensal of human skin".
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bacteria are susceptible to a wide range of antimicrobial molecules, from both pharmaceutical and natural sources. The antibiotics most frequently used to treat acne vulgaris are
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pathway in sebocytes, leading to a decrease in lipid synthesis and sebum production. SA also reduces the inflammatory response of sebocytes and decreases the proliferation of
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Gilchrist TC (1900). "A bacteriological and microscopical study of over 300 vesicular and pustular lesions of the skin, with a research upon the etiology of acne vulgaris".
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McLean RJ, Hussain AA, Sayer M, Vincent PJ, Hughes DJ, Smith TJ (September 1993). "Antibacterial activity of multilayer silver-copper surface films on catheter material".
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present on most healthy adult humans' skin. It is usually just barely detectable on the skin of healthy preadolescents. It lives, among other things, primarily on
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Kim J (2005). "Review of the innate immune response in acne vulgaris: activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses".
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Nisbet, M.; Briggs, S.; Ellis-Pegler, R.; Thomas, M. ;Holland, D. "Propionibacterium acnes: an under-appreciated cause of post-neurosurgical infection"
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Lu J, Cong T, Wen X, Li X, Du D, He G, Jiang X (October 2019). "Salicylic acid treats acne vulgaris by suppressing AMPK/SREBP1 pathway in sebocytes".
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Lang G, Buchbauer G (January 2012). "A review on recent research results (2008–2010) on essential oils as antimicrobials and antifungals. A review".
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Strauss JS, Krowchuk DP, Leyden JJ, Lucky AW, Shalita AR, Siegfried EC, et al. (April 2007). "Guidelines of care for acne vulgaris management".
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is especially sensitive to light in the 405–420 nanometer (near the ultraviolet) range due to an endogenic porphyrin–coporphyrin III. A total
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bacteria represents a growing problem worldwide. The problem is especially pronounced in North America and Europe. The antibiotic families that
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Leyden JJ, Wortzman M, Baldwin EK (December 2008). "Antibiotic-resistant Propionibacterium acnes suppressed by a benzoyl peroxide cleanser 6%".
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Ross JI, Snelling AM, Carnegie E, Coates P, Cunliffe WJ, Bettoli V, et al. (March 2003). "Antibiotic-resistant acne: lessons from Europe".
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Perry A., Lambert P. " Propionibacterium acnes: Infection beyond the skin." Expert Review of Anti-Infective Therapy. 9 (12) (pp 1149-1156), 2011
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Gharamti AA, Kanafani ZA (December 2017). "Cutibacterium (formerly Propionibacterium) acnes infections associated with implantable devices".
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Tuchayi, Sara Moradi; Makrantonaki, Evgenia; Ganceviciene, Ruta; Dessinioti, Clio; Feldman, Steven R.; Zouboulis, Christos C. (2015-09-17).
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Papageorgiou P, Katsambas A, Chu A (May 2000). "Phototherapy with blue (415 nm) and red (660 nm) light in the treatment of acne vulgaris".
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Albietz JM, Lenton LM (October 2006). "Effect of antibacterial honey on the ocular flora in tear deficiency and meibomian gland disease".
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in follicles can trigger inflammation. This inflammation can lead to the symptoms associated with some common skin disorders, such as
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structure and DNA G + C content, the cutaneous species was distinguishable from other species that had been previously categorized as
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that is closely related to the human-associated strains. The two lines diverged roughly 7,000 years ago, at about the same time when
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Tzellos T, Zampeli V, Makrantonaki E, Zouboulis CC (June 2011). "Treating acne with antibiotic-resistant bacterial colonization".
4519: 4042: 3828: 2985: 2262: 4524: 2196:"Population genetic analysis of Propionibacterium acnes identifies a subpopulation and epidemic clones associated with acne" 1382: 4606: 895: 4166: 4145: 4110: 3944: 4232: 4445: 4037: 3757: 1457: 1409: 4012: 4601: 4550: 4364: 2694: 1173:"Draft Genome Sequences of Propionibacterium acnes Type Strain ATCC6919 and Antibiotic-Resistant Strain HL411PA1" 4081: 4071: 3978: 3215:"Chemical composition and biological activities of essential oils extracted from Korean endemic citrus species" 3147:"The antibacterial activity of clove essential oil against Propionibacterium acnes and its mechanism of action" 3328:
Libenson L, Hadley FP, Mcilroy AP, Wetzel VM, Mellon RR (1953). "Antibacterial effect of elemental sulfur".
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and is associated with disease activity, but it can also be found in 23% of controls. The subspecies of
3890: 494: 1458:"Cutibacterium (Formerly Propionibacterium) avidum: A Rare but Avid Agent of Prosthetic Hip Infection" 4560: 4221: 4005: 3939: 2536: 1028:"Cutibacterium acnes (Propionibacterium acnes) and acne vulgaris: a brief look at the latest updates" 3726: 4358: 4022: 3836: 3701: 3697: 3643:"Interkingdom transfer of the acne-causing agent, Propionibacterium acnes, from human to grapevine" 687: 454: 3713: 3214: 3010:"Efficacy of chlorhexidine gluconate ointment (Oronine H(®)) for experimentally-induced comedones" 4260: 4246: 4027: 3856: 3798: 2366:
Emery DC, Shoemark DK, Batstone TE, Waterfall CM, Coghill JA, Cerajewska TL, et al. (2017).
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Capoor MN, Ruzicka F, Schmitz JE, James GA, Machackova T, Jancalek R, et al. (2017-04-03).
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was taxonomically reclassified as a result of biochemical and genomic studies. In terms of both
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Holland C, Mak TN, Zimny-Arndt U, Schmid M, Meyer TF, Jungblut PR, Brüggemann H (August 2010).
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bacteria, including quinolones, cephalosporins, pleuromutilins, penicillins, and sulfonamides.
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Campisano A, Ometto L, Compant S, Pancher M, Antonielli L, Yousaf S, et al. (May 2014).
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Yamakoshi T, Makino T, Matsunaga K, Yoshihisa Y, Rehman MU, Seki T, et al. (July 2012).
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and the associated inflammation make the affected tissue more susceptible to colonization by
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Perry A, Lambert P (December 2011). "Propionibacterium acnes: infection beyond the skin".
8: 4288: 4183: 4086: 4066: 3973: 3895: 3807: 1778: 1700:"Recent advances in understanding Propionibacterium acnes ( Cutibacterium acnes) in acne" 864: 644: 258: 87: 3462: 2211: 2076: 1674: 1233: 4380: 4296: 4133: 4076: 3963: 3618: 3591: 3572: 3529: 3481: 3442: 3423: 3269: 3257: 3127: 3115: 3084: 3036: 3009: 2897: 2853: 2802: 2768: 2740: 2493: 2445: 2418: 2394: 2367: 2277:"Propionibacterium acnes postoperative shoulder arthritis: an emerging clinical entity" 2230: 2195: 2144: 2119: 2095: 2060: 2041: 1981: 1956: 1932: 1897: 1845: 1811: 1652: 1621: 1573: 1546: 1523: 1485: 1296: 1253: 1197: 1172: 461:(commonly known as Accutane) are being used on patients with severe or resistant acne. 231: 184: 40: 2671: 2646: 2622: 2598:"Antimicrobiol susceptibility of Propinibacterium acnes and related microbial species" 2597: 2419:"Propionibacterium acnes: an underestimated pathogen in implant-associated infections" 1359: 1334: 4568: 3988: 3912: 3664: 3623: 3564: 3560: 3521: 3517: 3486: 3427: 3415: 3380: 3345: 3310: 3261: 3226: 3168: 3119: 3076: 3041: 2981: 2970: 2924: 2889: 2885: 2845: 2833: 2794: 2782: 2732: 2676: 2627: 2578: 2497: 2485: 2450: 2399: 2339: 2334: 2317: 2298: 2235: 2176: 2149: 2100: 2033: 2025: 1986: 1937: 1875: 1837: 1825: 1760: 1752: 1656: 1613: 1578: 1527: 1477: 1431: 1364: 1288: 1245: 1202: 1153: 1148: 1139: 1123: 1059: 994: 778:
has also been shown to have some antibacterial properties that may be active against
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Levy PY, Fenollar F, Stein A, Borrione F, Cohen E, Lebail B, Raoult D (June 2008).
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Vanity, Vitality, and Virility: The Chemistry Behind the Products You Love to Buy
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Zeller VA, Letembet VA, Meyssonnier VA, Heym B, Ziza JM, Marmor SD (July 2018).
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Dréno B, Pécastaings S, Corvec S, Veraldi S, Khammari A, Roques C (June 2018).
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Bayston R, Vera L, Mills A, Ashraf W, Stevenson O, Howdle SM (February 2010).
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was created for the cutaneous species, including those formerly identified as
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Liu J, Cheng A, Bangayan NJ, Barnard E, Curd E, Craft N, Li H (August 2014).
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Ross; et al. (2003). "Antibiotic-resistant acne: lessons from Europe".
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bacteria are susceptible to many types of antimicrobial chemicals found in
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Blaskovich MA, Elliott AG, Kavanagh AM, Ramu S, Cooper MA (October 2019).
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Some other antimicrobials like salicylic acid have been proven to inhibit
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Fournière M, Latire T, Souak D, Feuilloley MG, Bedoux G (November 2020).
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have also been demonstrated to be toxic towards many bacteria, including
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Baik JS, Kim SS, Lee JA, Oh TH, Kim JY, Lee NH, Hyun CG (January 2008).
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Antimicrobial Activity of Acne Drugs Against Skin-Associated Bacteria"
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Fu Y, Chen L, Zu Y, Liu Z, Liu X, Liu Y, et al. (January 2009).
1383:"Propionibacterium Cutibacterium - late breaking news and a new name" 891: 883: 879: 844: 767: 729: 698: 238: 4401: 3376: 2647:"Susceptibility of Propionibacterium acnes to seventeen antibiotics" 506:
species is not known. Current research has pointed to the idea that
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are also found much more frequently in acne and can induce distinct
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International Journal of Systematic and Evolutionary Microbiology
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Several naturally occurring molecules and compounds are toxic to
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Shoulder Arthritis / Rotator Cuff Tears: causes of shoulder pain
623:(synovitis, acne, pustulosis, hyperostosis, osteitis) syndrome, 492:, while unhealthy ones universally include the nonpore-resident 4472: 3686: 794: 790: 786: 270: 262: 3549:
Journal of the European Academy of Dermatology and Venereology
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Journal of the European Academy of Dermatology and Venereology
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1865: 1455: 1025: 775: 640: 422:. Acne vulgaris is the disease most commonly associated with 388: 301: 1408:
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863:. Its photosensitivity can be enhanced by pretreatment with 3327: 2416: 1544: 1407: 584:
appears to be more often associated with virulent strains.
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Zouboulis CC (2011). "Acne and sebaceous gland function".
1121: 909:, to highlight its unexpected and unconventional habitat. 3362: 2537:"The Cause Of Acne and Natural or Medical Acne Treatment" 2318:"Infective endocarditis due to Propionibacterium species" 2274: 2058: 3503: 2315: 1104: 2870: 2645:
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1957:"Staphylococcus epidermidis--the 'accidental' pathogen" 1170: 3286: 2695:"Antibiotic Susceptibility of Propionibacterium acnes" 2644: 379:
bacteria predominantly live deep within follicles and
2914: 2757: 2514:. Skincarephysicians.com. 2007-02-16. Archived from 1697: 3101: 2417:Portillo ME, Corvec S, Borens O, Trampuz A (2013). 1675:"Understanding Acne - News in Health, January 2010" 1105:Bhatia A, Maisonneuve JF, Persing DH (2004-01-01). 3596:Clinical, Cosmetic and Investigational Dermatology 3014:Clinical, Cosmetic and Investigational Dermatology 2969: 2595: 1868:Sarcoidosis, Vasculitis, and Diffuse Lung Diseases 631:. It is also suspected a main bacterial source of 1335:"The Taxonomic Position of Corynebacterium acnes" 1264: 697:are most likely to acquire resistance to are the 410:bacterial debris produced by the rapid growth of 265:has been sequenced and a study has shown several 4588: 2596:Hoeffler U, Ko HL, Pulverer G (September 1976). 2467: 619:may play a role in other conditions, including 3058: 650: 2563:Journal of the American Academy of Dermatology 3742: 3243: 3185: 2193: 1332: 1115: 1108:Proprionibacterium acnes and Chronic Diseases 894:agriculture may have been established. This 843:, possibly due to the presence of endogenous 464: 339:. As part of restructuring, the novel genus 3212: 3206: 3052: 2512:"Prescription Medications for Treating Acne" 1270: 1100: 1098: 967: 886:appears to host an endophytic population of 227:) is the relatively slow-growing, typically 3540: 3397: 3144: 521: 3749: 3735: 31: 3700:at the U.S. National Library of Medicine 3658: 3617: 3607: 3480: 3470: 3304: 3293:The Journal of Antimicrobial Chemotherapy 3219:Journal of Microbiology and Biotechnology 3162: 3035: 3025: 2772: 2670: 2621: 2444: 2434: 2393: 2383: 2333: 2292: 2229: 2219: 2166: 2143: 2094: 2084: 1980: 1931: 1921: 1815: 1715: 1638: 1572: 1562: 1509: 1425: 1358: 1313: 1307: 1196: 1147: 1095: 1053: 1043: 988: 774:contain antibacterial chemicals. Natural 587: 2461: 2410: 2003: 1401: 963: 961: 959: 957: 681: 437: 399:) or blockage of the follicle can cause 281:that may be immunogenic (activating the 4043:Extensively drug-resistant tuberculosis 3497: 3001: 2470:Expert Review of Anti-Infective Therapy 1326: 1273:Expert Review of Anti-Infective Therapy 1021: 1019: 1017: 1015: 4589: 3829:Arcanobacterium haemolyticum infection 3722:- the Bacterial Diversity Metadatabase 3589: 2967: 2961: 1449: 926: 924: 922: 639:brains. It is a common contaminant in 571:of approximately 70% of patients with 308:. It may also be found throughout the 4406: 4405: 3730: 3634: 2651:Antimicrobial Agents and Chemotherapy 2602:Antimicrobial Agents and Chemotherapy 2263:Journal of Antimicrobial Chemotherapy 2167:Inoue Y, Suga M (February 2008). 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Characterization of phylotypes of 304:secreted by sebaceous glands in the 257:, the latter particularly following 3583: 2322:Clinical Microbiology and Infection 1595: 1414:Clinical Microbiology and Infection 1333:Douglas HC, Gunter SE (July 1946). 1070: 936:Prokaryotic Nomenclature Up-to-Date 919: 831: 366: 13: 3945:Tuberculous cervical lymphadenitis 3506:The British Journal of Dermatology 3330:The Journal of Infectious Diseases 3258:10.1097/01.ico.0000225716.85382.7b 3116:10.1111/j.1472-765x.1995.tb01051.x 2874:The British Journal of Dermatology 2822:The British Journal of Dermatology 2761:The British Journal of Dermatology 2265:. 60(5). NOV 2007. 1097-1103.1103. 1886: 1688: 1653:10.1016/j.clindermatol.2004.03.004 1524:10.1016/j.clindermatol.2004.03.004 724:antibacterial products, including 544: 14: 4618: 4038:Multi-drug-resistant tuberculosis 3758:Gram-positive bacterial infection 3679: 2947:U.S. Food and Drug Administration 2717:Expert Opinion on Pharmacotherapy 870: 4013:Primary inoculation tuberculosis 3685: 3561:10.1111/j.1468-3083.2008.02781.x 3518:10.1046/j.1365-2133.2000.03481.x 3365:Canadian Journal of Microbiology 2886:10.1046/j.1365-2133.2002.04690.x 2834:10.1046/j.1365-2133.2003.05067.x 2783:10.1046/j.1365-2133.2001.03956.x 2335:10.1111/j.1469-0691.2009.02703.x 1826:10.1046/j.1365-2133.2003.05067.x 1140:10.1128/AAC.45.10.2969-2970.2001 1111:. National Academies Press (US). 371: 363:is an active field of research. 44: 4365:Group JK corynebacterium sepsis 3647:Molecular Biology and Evolution 3434: 3391: 3356: 3321: 3280: 3237: 3179: 3138: 3104:Letters in Applied Microbiology 3095: 2935: 2908: 2864: 2813: 2751: 2708: 2697:. ScienceOfAcne.com. 2011-07-15 2687: 2638: 2589: 2554: 2529: 2504: 2372:Frontiers in Aging Neuroscience 2359: 2350: 2309: 2268: 2255: 2246: 2187: 2160: 2111: 2052: 1997: 1948: 1795: 1771: 1724: 1667: 1632: 1589: 1538: 1503: 1375: 403:bacteria to grow and multiply. 4082:Borderline lepromatous leprosy 4072:Borderline tuberculoid leprosy 3979:Tuberculosis cutis orificialis 1804:British Journal of Dermatology 1737:Nature Reviews Disease Primers 1717:10.12688/f1000research.15659.1 1213: 1164: 559: 537:. The pathogen may also cause 1: 3188:Flavour and Fragrance Journal 3164:10.1001/archdermatol.2008.549 2976:. Oxford University. p.  2482:10.1080/14787210.2017.1404452 2423:BioMed Research International 1923:10.3390/microorganisms8111752 1316:Johns Hopkins Hospital Report 912: 839:glows orange when exposed to 749: 529:is a common cause of chronic 4345:Corynebacterium minutissimum 4190:Mycobacterium intracellulare 3823:Arcanobacterium haemolyticum 2729:10.1517/14656566.2011.553192 2281:Clinical Infectious Diseases 2221:10.1371/journal.pone.0012277 2086:10.1371/journal.pone.0174518 2022:10.1097/ICL.0000000000000281 651:Antimicrobial susceptibility 356:Propionibacterium granulosum 323:for its ability to generate 249:; it can also cause chronic 7: 4331:Corynebacterium diphtheriae 3590:Wan MT, Lin JY (May 2014). 1462:The Journal of Arthroplasty 10: 4623: 4607:Bacteria described in 1946 3472:10.1038/s41598-019-50746-4 2575:10.1016/j.jaad.2006.08.048 1900:Staphylococcus epidermidis 1474:10.1016/j.arth.2018.02.008 1351:10.1128/JB.52.1.15-23.1946 495:Staphylococcus epidermidis 4414: 4379: 4320: 4278: 4231: 4165: 4144: 4109: 4100: 4051: 4006:Papulonecrotic tuberculid 3940:Tuberculous lymphadenitis 3888: 3879: 3870: 3846: 3777: 3768: 2968:Emsley J (July 1, 2004). 2136:10.1007/s00586-013-2675-y 1955:Otto, M (7 August 2009). 1427:10.1016/j.cmi.2018.03.010 442:Comedo acne from C. acnes 315:Originally identified as 190: 183: 156: 151: 136: 129: 41:Scientific classification 39: 30: 23: 4359:Corynebacterium jeikeium 4023:Tuberculous pericarditis 3837:Actinomyces gerencseriae 3702:Medical Subject Headings 3400:Experimental Dermatology 2385:10.3389/fnagi.2017.00195 1564:10.1186/1471-2180-10-230 1189:10.1128/genomeA.00740-14 878:has been found to be an 709:(e.g., clindamycin) and 701:(e.g., erythromycin and 522:Ophthalmic complications 435:to combat against acne. 350:Propionibacterium avidum 4446:Propionibacterium acnes 4028:Urogenital tuberculosis 3857:Propionibacterium acnes 3799:Cutaneous actinomycosis 3716:Propionibacterium acnes 3698:Propionibacterium+acnes 3692:Propionibacterium acnes 3151:Archives of Dermatology 1339:Journal of Bacteriology 1242:10.1126/science.1100330 847:. It is also killed by 742:chlorhexidine gluconate 613:prosthetic heart valves 595:is often considered an 345:Propionibacterium acnes 321:Propionibacterium acnes 288:The species is largely 224:Propionibacterium acnes 204:Propionibacterium acnes 146:Scholz and Kilian, 2016 4602:Gram-positive bacteria 4033:Tuberculous dactylitis 3984:Tuberculous cellulitis 3342:10.1093/infdis/93.1.28 2124:European Spine Journal 2010:Eye & Contact Lens 1783:emedicine.medscape.com 1677:. Newsinhealth.nih.gov 1641:Clinics in Dermatology 1512:Clinics in Dermatology 990:10.1099/ijsem.0.001367 938:. DSMZ. Archived from 932:"Genus: Cutibacterium" 597:opportunistic pathogen 588:Opportunistic diseases 569:bronchoalveolar lavage 480:opportunistic bacteria 443: 310:gastrointestinal tract 4390:Gardnerella vaginalis 4293:Nocardia brasiliensis 3660:10.1093/molbev/msu075 3073:10.1055/s-2007-981614 1078:"Genus Cutibacterium" 682:Antibiotic-resistance 615:(predominantly men). 485:Staphylococcus aureus 474:The damage caused by 455:antibiotic resistance 441: 397:sebaceous hyperplasia 319:, it was later named 3996:Lichen scrofulosorum 3848:Propionibacteriaceae 3788:Actinomyces israelii 3694:at Wikimedia Commons 2663:10.1128/aac.11.1.171 2614:10.1128/aac.10.3.387 1749:10.1038/nrdp.2015.29 1177:Genome Announcements 882:of plants. Notably, 688:antibiotic-resistant 502:and this particular 241:(rod) linked to the 98:Propionibacteriaceae 16:Species of bacterium 4597:Propionibacteriales 4538:cutibacterium-acnes 4416:Cutibacterium acnes 4289:Nocardia asteroides 4184:Mycobacterium avium 4087:Lepromatous leprosy 4067:Tuberculoid leprosy 3808:Tropheryma whipplei 3609:10.2147/CCID.S35334 3463:2019NatSR...914658B 3027:10.2147/CCID.S33361 2949:. December 19, 2017 2436:10.1155/2013/804391 2212:2010PLoSO...512277L 2077:2017PLoSO..1274518C 1973:10.1038/nrmicro2182 1904:Cutibacterium acnes 1234:2004Sci...305..671B 876:Cutibacterium acnes 865:aminolevulinic acid 837:Cutibacterium acnes 656:Cutibacterium acnes 645:cerebrospinal fluid 637:Alzheimer's disease 593:Cutibacterium acnes 565:Cutibacterium acnes 550:Cutibacterium acnes 527:Cutibacterium acnes 407:Cutibacterium acnes 377:Cutibacterium acnes 259:intraocular surgery 218:Cutibacterium acnes 140:Cutibacterium acnes 88:Propionibacteriales 25:Cutibacterium acnes 4381:Bifidobacteriaceae 4322:Corynebacteriaceae 4297:Nocardia farcinica 4134:Aquarium granuloma 4077:Borderline leprosy 3964:Erythema induratum 3451:Scientific Reports 3306:10.1093/jac/dkp420 1285:10.1586/eri.11.137 762:such as rosemary, 552:has been found in 444: 4584: 4583: 4569:Open Tree of Life 4408:Taxon identifiers 4399: 4398: 4375: 4374: 4274: 4273: 4270: 4269: 3989:Tuberculous gumma 3872:Corynebacterineae 3866: 3865: 3815:Whipple's disease 3708:Propionibacterium 3690:Media related to 3412:10.1111/exd.13934 2987:978-0-19-280509-6 2476:(12): 1083–1094. 1610:10.1159/000087011 1420:(11): 1149–1155. 1045:10.1111/jdv.15043 1038:(Suppl 2): 5–14. 983:(11): 4422–4432. 942:on 17 August 2018 849:ultraviolet light 686:The emergence of 633:neuroinflammation 611:in patients with 333:phylogenetic tree 214: 213: 208: 200: 4614: 4577: 4576: 4564: 4563: 4554: 4553: 4541: 4540: 4528: 4527: 4515: 4514: 4502: 4501: 4489: 4488: 4476: 4475: 4463: 4462: 4450: 4449: 4448: 4435: 4434: 4433: 4403: 4402: 4311:Rhodococcus equi 4107: 4106: 3974:Prosector's wart 3886: 3885: 3881:Mycobacteriaceae 3877: 3876: 3779:Actinomycetaceae 3775: 3774: 3751: 3744: 3737: 3728: 3727: 3710:(Kenyon College) 3689: 3673: 3672: 3662: 3638: 3632: 3631: 3621: 3611: 3587: 3581: 3580: 3544: 3538: 3537: 3501: 3495: 3494: 3484: 3474: 3438: 3432: 3431: 3395: 3389: 3388: 3360: 3354: 3353: 3325: 3319: 3318: 3308: 3284: 3278: 3277: 3241: 3235: 3234: 3210: 3204: 3203: 3200:10.1002/ffj.2082 3183: 3177: 3176: 3166: 3142: 3136: 3135: 3099: 3093: 3092: 3056: 3050: 3049: 3039: 3029: 3005: 2999: 2998: 2996: 2994: 2975: 2965: 2959: 2958: 2956: 2954: 2939: 2933: 2932: 2912: 2906: 2905: 2868: 2862: 2861: 2817: 2811: 2810: 2776: 2755: 2749: 2748: 2712: 2706: 2705: 2703: 2702: 2691: 2685: 2684: 2674: 2642: 2636: 2635: 2625: 2593: 2587: 2586: 2558: 2552: 2551: 2549: 2548: 2539:. Archived from 2533: 2527: 2526: 2524: 2523: 2508: 2502: 2501: 2465: 2459: 2458: 2448: 2438: 2414: 2408: 2407: 2397: 2387: 2363: 2357: 2354: 2348: 2347: 2337: 2313: 2307: 2306: 2296: 2272: 2266: 2259: 2253: 2250: 2244: 2243: 2233: 2223: 2191: 2185: 2184: 2164: 2158: 2157: 2147: 2115: 2109: 2108: 2098: 2088: 2056: 2050: 2049: 2001: 1995: 1994: 1984: 1952: 1946: 1945: 1935: 1925: 1893: 1884: 1883: 1863: 1854: 1853: 1819: 1799: 1793: 1792: 1790: 1789: 1775: 1769: 1768: 1728: 1722: 1721: 1719: 1695: 1686: 1685: 1683: 1682: 1671: 1665: 1664: 1636: 1630: 1629: 1593: 1587: 1586: 1576: 1566: 1551:BMC Microbiology 1542: 1536: 1535: 1507: 1501: 1500: 1498: 1496: 1468:(7): 2246–2250. 1453: 1447: 1446: 1444: 1442: 1429: 1405: 1399: 1398: 1396: 1394: 1379: 1373: 1372: 1362: 1330: 1324: 1323: 1311: 1305: 1304: 1268: 1262: 1261: 1217: 1211: 1210: 1200: 1183:(4): e00740–14. 1168: 1162: 1161: 1151: 1119: 1113: 1112: 1102: 1093: 1092: 1090: 1088: 1074: 1068: 1067: 1057: 1047: 1023: 1010: 1009: 1007: 1005: 992: 974: 965: 952: 951: 949: 947: 928: 857:radiant exposure 832:Photosensitivity 758:bacteria. Some 726:benzoyl peroxide 722:over-the-counter 567:can be found in 535:cataract surgery 433:immune responses 393:sebaceous glands 367:Role in diseases 292:and part of the 206: 198: 175:subsp. elongatum 168:subsp. defendens 142: 49: 48: 35: 21: 20: 4622: 4621: 4617: 4616: 4615: 4613: 4612: 4611: 4587: 4586: 4585: 4580: 4572: 4567: 4559: 4557: 4549: 4544: 4536: 4531: 4523: 4518: 4510: 4505: 4497: 4492: 4484: 4479: 4471: 4466: 4458: 4453: 4444: 4443: 4438: 4429: 4428: 4423: 4410: 4400: 4395: 4371: 4316: 4266: 4227: 4161: 4140: 4096: 4092:Histoid leprosy 4047: 3894: 3891:M. tuberculosis 3862: 3842: 3764: 3755: 3714:Type strain of 3682: 3677: 3676: 3639: 3635: 3588: 3584: 3545: 3541: 3502: 3498: 3439: 3435: 3396: 3392: 3377:10.1139/m93-134 3361: 3357: 3326: 3322: 3285: 3281: 3242: 3238: 3211: 3207: 3184: 3180: 3143: 3139: 3100: 3096: 3067:(12): 1275–80. 3057: 3053: 3006: 3002: 2992: 2990: 2988: 2966: 2962: 2952: 2950: 2941: 2940: 2936: 2913: 2909: 2869: 2865: 2818: 2814: 2756: 2752: 2713: 2709: 2700: 2698: 2693: 2692: 2688: 2643: 2639: 2594: 2590: 2559: 2555: 2546: 2544: 2535: 2534: 2530: 2521: 2519: 2510: 2509: 2505: 2466: 2462: 2415: 2411: 2364: 2360: 2355: 2351: 2314: 2310: 2273: 2269: 2260: 2256: 2251: 2247: 2192: 2188: 2165: 2161: 2116: 2112: 2071:(4): e0174518. 2057: 2053: 2002: 1998: 1961:Nat Rev Microbi 1953: 1949: 1894: 1887: 1864: 1857: 1800: 1796: 1787: 1785: 1777: 1776: 1772: 1733:"Acne vulgaris" 1729: 1725: 1696: 1689: 1680: 1678: 1673: 1672: 1668: 1637: 1633: 1594: 1590: 1543: 1539: 1508: 1504: 1494: 1492: 1454: 1450: 1440: 1438: 1406: 1402: 1392: 1390: 1389:. April 2, 2017 1381: 1380: 1376: 1331: 1327: 1312: 1308: 1279:(12): 1149–56. 1269: 1265: 1228:(5684): 671–3. 1218: 1214: 1169: 1165: 1134:(10): 2969–70. 1120: 1116: 1103: 1096: 1086: 1084: 1076: 1075: 1071: 1024: 1013: 1003: 1001: 972: 966: 955: 945: 943: 930: 929: 920: 915: 873: 834: 826:4000–8000 μg/mL 752: 684: 653: 607:infections and 590: 562: 554:herniated discs 547: 545:Disk herniation 531:endophthalmitis 524: 472: 446: 374: 369: 255:endophthalmitis 147: 144: 138: 125: 43: 17: 12: 11: 5: 4620: 4610: 4609: 4604: 4599: 4582: 4581: 4579: 4578: 4565: 4555: 4542: 4529: 4516: 4503: 4490: 4477: 4464: 4451: 4436: 4420: 4418: 4412: 4411: 4397: 4396: 4394: 4393: 4385: 4383: 4377: 4376: 4373: 4372: 4370: 4369: 4368: 4367: 4355: 4354: 4353: 4341: 4340: 4339: 4326: 4324: 4318: 4317: 4315: 4314: 4307: 4306: 4305: 4284: 4282: 4276: 4275: 4272: 4271: 4268: 4267: 4265: 4264: 4257: 4250: 4242: 4240: 4229: 4228: 4226: 4225: 4222:M. haemophilum 4218: 4217: 4216: 4204: 4203: 4202: 4172: 4170: 4163: 4162: 4160: 4159: 4151: 4149: 4142: 4141: 4139: 4138: 4137: 4136: 4124: 4116: 4114: 4104: 4102:Nontuberculous 4098: 4097: 4095: 4094: 4089: 4084: 4079: 4074: 4069: 4059: 4057: 4049: 4048: 4046: 4045: 4040: 4035: 4030: 4025: 4020: 4015: 4010: 4009: 4008: 3998: 3993: 3992: 3991: 3986: 3981: 3976: 3971: 3969:Lupus vulgaris 3966: 3961: 3949: 3948: 3947: 3937: 3936: 3935: 3930: 3920: 3915: 3913:Ghon's complex 3901: 3899: 3883: 3874: 3868: 3867: 3864: 3863: 3861: 3860: 3852: 3850: 3844: 3843: 3841: 3840: 3833: 3832: 3831: 3819: 3818: 3817: 3803: 3802: 3801: 3796: 3783: 3781: 3772: 3770:Actinomycineae 3766: 3765: 3762:Actinomycetota 3754: 3753: 3746: 3739: 3731: 3725: 3724: 3711: 3705: 3695: 3681: 3680:External links 3678: 3675: 3674: 3653:(5): 1059–65. 3633: 3582: 3539: 3496: 3433: 3406:(7): 786–794. 3390: 3355: 3320: 3279: 3236: 3205: 3178: 3137: 3094: 3051: 3000: 2986: 2960: 2934: 2907: 2863: 2812: 2750: 2723:(8): 1233–47. 2707: 2686: 2637: 2588: 2553: 2528: 2503: 2460: 2409: 2358: 2349: 2308: 2294:10.1086/588477 2287:(12): 1884–6. 2267: 2254: 2245: 2186: 2159: 2130:(4): 697–707. 2110: 2051: 2016:(5): 330–333. 1996: 1967:(8): 555–567. 1947: 1910:Microorganisms 1885: 1874:(3): 197–203. 1855: 1794: 1770: 1723: 1687: 1666: 1631: 1588: 1537: 1502: 1448: 1400: 1374: 1325: 1306: 1263: 1212: 1163: 1114: 1094: 1069: 1011: 953: 917: 916: 914: 911: 872: 871:Other habitats 869: 833: 830: 809:Salicylic acid 760:essential oils 751: 748: 738:salicylic acid 683: 680: 652: 649: 589: 586: 561: 558: 546: 543: 539:corneal ulcers 523: 520: 512:S. epidermidis 504:Staphylococcus 471: 466:Staphylococcus 463: 373: 370: 368: 365: 325:propionic acid 317:Bacillus acnes 273:for degrading 212: 211: 210: 209: 201: 199:Gilchrist 1900 195:Bacillus acnes 188: 187: 181: 180: 179: 178: 171: 164: 154: 153: 149: 148: 145: 134: 133: 127: 126: 119: 117: 113: 112: 105: 101: 100: 95: 91: 90: 85: 81: 80: 75: 71: 70: 68:Actinomycetota 65: 61: 60: 55: 51: 50: 37: 36: 28: 27: 15: 9: 6: 4: 3: 2: 4619: 4608: 4605: 4603: 4600: 4598: 4595: 4594: 4592: 4575: 4570: 4566: 4562: 4556: 4552: 4547: 4543: 4539: 4534: 4530: 4526: 4521: 4517: 4513: 4508: 4504: 4500: 4495: 4491: 4487: 4482: 4478: 4474: 4469: 4465: 4461: 4456: 4452: 4447: 4441: 4437: 4432: 4426: 4422: 4421: 4419: 4417: 4413: 4409: 4404: 4392: 4391: 4387: 4386: 4384: 4382: 4378: 4366: 4363: 4362: 4361: 4360: 4356: 4352: 4349: 4348: 4347: 4346: 4342: 4338: 4335: 4334: 4333: 4332: 4328: 4327: 4325: 4323: 4319: 4313: 4312: 4308: 4304: 4301: 4300: 4299: 4298: 4294: 4290: 4286: 4285: 4283: 4281: 4277: 4263: 4262: 4258: 4256: 4255: 4251: 4249: 4248: 4244: 4243: 4241: 4238: 4234: 4230: 4224: 4223: 4219: 4215: 4212: 4211: 4210: 4209: 4205: 4201: 4200:MAI infection 4198: 4197: 4196: 4192: 4191: 4186: 4185: 4180: 4178: 4174: 4173: 4171: 4168: 4164: 4158: 4157: 4153: 4152: 4150: 4147: 4143: 4135: 4132: 4131: 4130: 4129: 4125: 4123: 4122: 4118: 4117: 4115: 4112: 4108: 4105: 4103: 4099: 4093: 4090: 4088: 4085: 4083: 4080: 4078: 4075: 4073: 4070: 4068: 4064: 4061: 4060: 4058: 4056: 4055: 4050: 4044: 4041: 4039: 4036: 4034: 4031: 4029: 4026: 4024: 4021: 4019: 4016: 4014: 4011: 4007: 4004: 4003: 4002: 3999: 3997: 3994: 3990: 3987: 3985: 3982: 3980: 3977: 3975: 3972: 3970: 3967: 3965: 3962: 3960: 3959:Scrofuloderma 3957: 3956: 3955: 3954: 3950: 3946: 3943: 3942: 3941: 3938: 3934: 3931: 3929: 3926: 3925: 3924: 3921: 3919: 3916: 3914: 3910: 3906: 3903: 3902: 3900: 3898: 3897: 3892: 3887: 3884: 3882: 3878: 3875: 3873: 3869: 3859: 3858: 3854: 3853: 3851: 3849: 3845: 3839: 3838: 3834: 3830: 3827: 3826: 3825: 3824: 3820: 3816: 3813: 3812: 3810: 3809: 3804: 3800: 3797: 3795: 3794:Actinomycosis 3792: 3791: 3790: 3789: 3785: 3784: 3782: 3780: 3776: 3773: 3771: 3767: 3763: 3759: 3752: 3747: 3745: 3740: 3738: 3733: 3732: 3729: 3723: 3721: 3717: 3712: 3709: 3706: 3703: 3699: 3696: 3693: 3688: 3684: 3683: 3670: 3666: 3661: 3656: 3652: 3648: 3644: 3637: 3629: 3625: 3620: 3615: 3610: 3605: 3601: 3597: 3593: 3586: 3578: 3574: 3570: 3566: 3562: 3558: 3554: 3550: 3543: 3535: 3531: 3527: 3523: 3519: 3515: 3511: 3507: 3500: 3492: 3488: 3483: 3478: 3473: 3468: 3464: 3460: 3456: 3452: 3448: 3446: 3437: 3429: 3425: 3421: 3417: 3413: 3409: 3405: 3401: 3394: 3386: 3382: 3378: 3374: 3370: 3366: 3359: 3351: 3347: 3343: 3339: 3335: 3331: 3324: 3316: 3312: 3307: 3302: 3299:(2): 258–65. 3298: 3294: 3290: 3283: 3275: 3271: 3267: 3263: 3259: 3255: 3252:(9): 1012–9. 3251: 3247: 3240: 3232: 3228: 3224: 3220: 3216: 3209: 3201: 3197: 3193: 3189: 3182: 3174: 3170: 3165: 3160: 3156: 3152: 3148: 3141: 3133: 3129: 3125: 3121: 3117: 3113: 3109: 3105: 3098: 3090: 3086: 3082: 3078: 3074: 3070: 3066: 3062: 3061:Planta Medica 3055: 3047: 3043: 3038: 3033: 3028: 3023: 3019: 3015: 3011: 3004: 2989: 2983: 2979: 2974: 2973: 2964: 2948: 2944: 2938: 2930: 2926: 2923:(6): 417–21. 2922: 2918: 2911: 2903: 2899: 2895: 2891: 2887: 2883: 2879: 2875: 2867: 2859: 2855: 2851: 2847: 2843: 2839: 2835: 2831: 2828:(3): 467–78. 2827: 2823: 2816: 2808: 2804: 2800: 2796: 2792: 2788: 2784: 2780: 2775: 2770: 2767:(2): 339–46. 2766: 2762: 2754: 2746: 2742: 2738: 2734: 2730: 2726: 2722: 2718: 2711: 2696: 2690: 2682: 2678: 2673: 2668: 2664: 2660: 2656: 2652: 2648: 2641: 2633: 2629: 2624: 2619: 2615: 2611: 2608:(3): 387–94. 2607: 2603: 2599: 2592: 2584: 2580: 2576: 2572: 2569:(4): 651–63. 2568: 2564: 2557: 2543:on 2017-10-11 2542: 2538: 2532: 2518:on 2012-06-20 2517: 2513: 2507: 2499: 2495: 2491: 2487: 2483: 2479: 2475: 2471: 2464: 2456: 2452: 2447: 2442: 2437: 2432: 2428: 2424: 2420: 2413: 2405: 2401: 2396: 2391: 2386: 2381: 2377: 2373: 2369: 2362: 2353: 2345: 2341: 2336: 2331: 2328:(4): 387–94. 2327: 2323: 2319: 2312: 2304: 2300: 2295: 2290: 2286: 2282: 2278: 2271: 2264: 2258: 2249: 2241: 2237: 2232: 2227: 2222: 2217: 2213: 2209: 2206:(8): e12277. 2205: 2201: 2197: 2190: 2182: 2178: 2175:(2): 115–30. 2174: 2170: 2163: 2155: 2151: 2146: 2141: 2137: 2133: 2129: 2125: 2121: 2114: 2106: 2102: 2097: 2092: 2087: 2082: 2078: 2074: 2070: 2066: 2062: 2055: 2047: 2043: 2039: 2035: 2031: 2027: 2023: 2019: 2015: 2011: 2007: 2000: 1992: 1988: 1983: 1978: 1974: 1970: 1966: 1962: 1958: 1951: 1943: 1939: 1934: 1929: 1924: 1919: 1915: 1911: 1907: 1905: 1901: 1892: 1890: 1881: 1877: 1873: 1869: 1862: 1860: 1851: 1847: 1843: 1839: 1835: 1831: 1827: 1823: 1818: 1813: 1810:(3): 467–78. 1809: 1805: 1798: 1784: 1780: 1774: 1766: 1762: 1758: 1754: 1750: 1746: 1742: 1738: 1734: 1727: 1718: 1713: 1709: 1705: 1704:F1000Research 1701: 1694: 1692: 1676: 1670: 1662: 1658: 1654: 1650: 1646: 1642: 1635: 1627: 1623: 1619: 1615: 1611: 1607: 1603: 1599: 1592: 1584: 1580: 1575: 1570: 1565: 1560: 1556: 1552: 1548: 1541: 1533: 1529: 1525: 1521: 1517: 1513: 1506: 1491: 1487: 1483: 1479: 1475: 1471: 1467: 1463: 1459: 1452: 1437: 1433: 1428: 1423: 1419: 1415: 1411: 1404: 1388: 1384: 1378: 1370: 1366: 1361: 1356: 1352: 1348: 1344: 1340: 1336: 1329: 1321: 1317: 1310: 1302: 1298: 1294: 1290: 1286: 1282: 1278: 1274: 1267: 1259: 1255: 1251: 1247: 1243: 1239: 1235: 1231: 1227: 1223: 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Retrieved 2971: 2963: 2951:. Retrieved 2946: 2937: 2920: 2916: 2910: 2880:(5): 840–8. 2877: 2873: 2866: 2825: 2821: 2815: 2764: 2760: 2753: 2720: 2716: 2710: 2699:. Retrieved 2689: 2657:(1): 171–3. 2654: 2650: 2640: 2605: 2601: 2591: 2566: 2562: 2556: 2545:. Retrieved 2541:the original 2531: 2520:. Retrieved 2516:the original 2506: 2473: 2469: 2463: 2426: 2422: 2412: 2375: 2371: 2361: 2352: 2325: 2321: 2311: 2284: 2280: 2270: 2257: 2248: 2203: 2199: 2189: 2172: 2168: 2162: 2127: 2123: 2113: 2068: 2064: 2054: 2013: 2009: 1999: 1964: 1960: 1950: 1916:(11): 1752. 1913: 1909: 1903: 1899: 1871: 1867: 1807: 1803: 1797: 1786:. Retrieved 1782: 1773: 1743:(1): 15029. 1740: 1736: 1726: 1707: 1703: 1679:. Retrieved 1669: 1647:(5): 360–6. 1644: 1640: 1634: 1604:(3): 193–8. 1601: 1597: 1591: 1554: 1550: 1540: 1518:(5): 360–6. 1515: 1511: 1505: 1493:. Retrieved 1465: 1461: 1451: 1439:. Retrieved 1417: 1413: 1403: 1391:. 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Retrieved 940:the original 935: 902: 896: 887: 875: 874: 860: 852: 836: 835: 821: 818: 805: 803: 798: 784: 779: 764:tea tree oil 755: 753: 746: 717: 715: 707:lincosamides 703:azithromycin 694: 690: 685: 675: 660:erythromycin 655: 654: 616: 609:endocarditis 592: 591: 576: 564: 563: 549: 548: 526: 525: 516: 511: 507: 503: 499: 493: 489: 483: 475: 473: 468: 465: 459:isotretinoin 449: 445: 423: 416:folliculitis 411: 406: 405: 400: 384: 376: 375: 360: 354: 348: 344: 340: 336: 328: 320: 316: 314: 287: 229:aerotolerant 223: 222: 217: 216: 215: 203: 194: 173: 166: 161:subsp. acnes 159: 139: 137: 121: 120: 108: 24: 18: 4494:iNaturalist 4440:Wikispecies 4303:Nocardiosis 4254:M. chelonae 4208:M. ulcerans 4156:M. gordonae 4121:M. kansasii 3225:(1): 74–9. 3157:(1): 86–8. 1598:Dermatology 1055:2434/620522 907:Frank Zappa 901:was dubbed 772:citrus oils 672:minocycline 668:doxycycline 664:clindamycin 625:sarcoidosis 573:sarcoidosis 560:Sarcoidosis 469:epidermidis 327:. In 2016, 298:fatty acids 251:blepharitis 152:Subspecies 4591:Categories 4351:Erythrasma 4337:Diphtheria 4128:M. marinum 4001:Tuberculid 3933:Rich focus 3928:Meningitis 3909:Ghon focus 3602:: 145–63. 2842:10454/3069 2791:10454/3311 2774:1510.02343 2701:2012-08-08 2547:2019-11-18 2522:2012-06-14 2429:: 804391. 1834:10454/3069 1788:2022-04-22 1681:2012-06-14 1322:: 409–430. 913:References 845:porphyrins 841:blacklight 750:Treatments 699:macrolides 647:cultures. 601:prostheses 533:following 482:, such as 294:skin flora 4054:M. leprae 3953:cutaneous 3428:108295123 3020:: 79–83. 2993:17 August 2953:17 August 2498:205850559 2030:1542-233X 1817:0706.4406 1757:2056-676X 1495:17 August 1441:17 August 1393:17 August 1087:17 August 1004:17 August 946:17 August 892:grapevine 884:grapevine 880:endophyte 814:mechanism 806:C. acnes. 768:clove oil 730:triclosan 716:However, 306:follicles 290:commensal 239:bacterium 232:anaerobic 116:Species: 4512:10032060 4431:Q2442109 4425:Wikidata 4177:M. avium 3896:M. bovis 3669:24554779 3628:24899818 3577:30935383 3569:18452529 3526:10809858 3491:31601845 3445:In vitro 3420:30972839 3350:13069766 3315:19942617 3274:12053077 3266:17133045 3231:18239420 3173:19153353 3089:37769650 3081:17893831 3046:22936850 2929:19181031 2894:12000382 2858:20838517 2850:12653738 2807:44614220 2799:11251569 2745:26957816 2737:21355786 2583:17276540 2490:29125405 2455:24308006 2404:28676754 2344:19260876 2303:18462110 2240:20808860 2200:PLOS ONE 2181:18326339 2154:23404353 2105:28369127 2065:PLOS ONE 2046:22829150 2038:27203796 1991:19609257 1942:33171837 1880:14620162 1850:20838517 1842:12653738 1765:27189872 1710:: 1953. 1661:15556719 1626:21459334 1618:16205063 1583:20799957 1532:15556719 1482:29544969 1436:29544912 1369:16561149 1301:42012357 1293:22114965 1258:26252335 1250:15286373 1207:25125638 1158:11583007 1064:29894579 999:27488827 897:C. acnes 888:C. acnes 861:in vitro 853:C. acnes 799:C. acnes 780:C. acnes 756:C. acnes 718:C. acnes 695:C. acnes 691:C. acnes 676:C. acnes 629:sciatica 617:C. acnes 577:C. acnes 508:C. acnes 500:C. acnes 490:C. acnes 476:C. acnes 450:C. acnes 429:biofilms 424:C. acnes 412:C. acnes 401:C. acnes 385:C. acnes 361:C. acnes 337:P. acnes 329:P. acnes 279:proteins 185:Synonyms 94:Family: 64:Phylum: 58:Bacteria 54:Domain: 4486:3225701 4455:BacDive 4179:complex 4063:Leprosy 4018:Miliary 3619:4038525 3534:9237317 3482:6787063 3459:Bibcode 3385:8242490 3132:5687026 3124:7576514 3037:3426266 2902:5725343 2446:3838805 2395:5476743 2378:: 195. 2231:2924382 2208:Bibcode 2169:Kekkaku 2145:3631045 2096:5378350 2073:Bibcode 1982:2807625 1933:7695133 1574:3224659 1557:: 230. 1490:3916758 1230:Bibcode 1222:Science 1198:4132614 899:subtype 271:enzymes 104:Genus: 84:Order: 74:Class: 4574:360356 4558:NZOR: 4525:965070 4499:356609 4473:971823 3718:at Bac 3704:(MeSH) 3667:  3626:  3616:  3575:  3567:  3532:  3524:  3489:  3479:  3426:  3418:  3383:  3348:  3313:  3272:  3264:  3246:Cornea 3229:  3171:  3130:  3122:  3087:  3079:  3044:  3034:  2984:  2927:  2900:  2892:  2856:  2848:  2805:  2797:  2743:  2735:  2681:836012 2679:  2672:351938 2669:  2632:984781 2630:  2623:429758 2620:  2581:  2496:  2488:  2453:  2443:  2402:  2392:  2342:  2301:  2238:  2228:  2179:  2152:  2142:  2103:  2093:  2044:  2036:  2028:  1989:  1979:  1940:  1930:  1878:  1848:  1840:  1763:  1755:  1659:  1624:  1616:  1581:  1571:  1530:  1488:  1480:  1434:  1367:  1360:518134 1357:  1299:  1291:  1256:  1248:  1205:  1195:  1156:  1146:  1062:  997:  903:Zappae 795:copper 793:, and 791:sulfur 787:silver 770:, and 670:, and 353:, and 263:genome 261:. Its 4507:IRMNG 4460:12636 3923:brain 3573:S2CID 3530:S2CID 3424:S2CID 3270:S2CID 3128:S2CID 3085:S2CID 2917:Cutis 2898:S2CID 2854:S2CID 2803:S2CID 2769:arXiv 2741:S2CID 2494:S2CID 2042:S2CID 1846:S2CID 1812:arXiv 1622:S2CID 1486:S2CID 1297:S2CID 1254:S2CID 1149:90767 973:(PDF) 822:acnes 776:honey 641:blood 621:SAPHO 605:shunt 389:sebum 381:pores 302:sebum 267:genes 4551:1747 4546:NCBI 4533:LPSN 4520:ITIS 4481:GBIF 3720:Dive 3665:PMID 3624:PMID 3565:PMID 3522:PMID 3487:PMID 3416:PMID 3381:PMID 3346:PMID 3311:PMID 3262:PMID 3227:PMID 3169:PMID 3120:PMID 3077:PMID 3042:PMID 2995:2018 2982:ISBN 2955:2018 2925:PMID 2890:PMID 2846:PMID 2795:PMID 2733:PMID 2677:PMID 2628:PMID 2579:PMID 2486:PMID 2451:PMID 2427:2013 2400:PMID 2340:PMID 2299:PMID 2236:PMID 2177:PMID 2150:PMID 2101:PMID 2034:PMID 2026:ISSN 1987:PMID 1938:PMID 1902:and 1876:PMID 1838:PMID 1761:PMID 1753:ISSN 1657:PMID 1614:PMID 1579:PMID 1528:PMID 1497:2018 1478:PMID 1443:2018 1432:PMID 1395:2018 1365:PMID 1289:PMID 1246:PMID 1203:PMID 1154:PMID 1089:2018 1082:LPSN 1060:PMID 1006:2018 995:PMID 948:2018 740:and 643:and 627:and 510:and 418:and 277:and 275:skin 253:and 247:acne 243:skin 4468:EoL 4195:MAP 3655:doi 3614:PMC 3604:doi 3557:doi 3514:doi 3510:142 3477:PMC 3467:doi 3408:doi 3373:doi 3338:doi 3301:doi 3254:doi 3196:doi 3159:doi 3155:145 3112:doi 3069:doi 3032:PMC 3022:doi 2978:130 2882:doi 2878:146 2838:hdl 2830:doi 2826:148 2787:hdl 2779:doi 2765:144 2725:doi 2667:PMC 2659:doi 2618:PMC 2610:doi 2571:doi 2478:doi 2441:PMC 2431:doi 2390:PMC 2380:doi 2330:doi 2289:doi 2226:PMC 2216:doi 2140:PMC 2132:doi 2091:PMC 2081:doi 2018:doi 1977:PMC 1969:doi 1928:PMC 1918:doi 1830:hdl 1822:doi 1808:148 1745:doi 1712:doi 1649:doi 1606:doi 1602:211 1569:PMC 1559:doi 1520:doi 1470:doi 1422:doi 1355:PMC 1347:doi 1281:doi 1238:doi 1226:305 1193:PMC 1185:doi 1144:PMC 1136:doi 1050:hdl 1040:doi 985:doi 705:), 635:in 300:in 285:). 4593:: 4571:: 4548:: 4535:: 4522:: 4509:: 4496:: 4483:: 4470:: 4457:: 4442:: 4427:: 4237:RG 4233:R4 4167:R3 4146:R2 4111:R1 4065:: 3907:: 3811:" 3760:: 3663:. 3651:31 3649:. 3645:. 3622:. 3612:. 3598:. 3594:. 3571:. 3563:. 3553:23 3551:. 3528:. 3520:. 3508:. 3485:. 3475:. 3465:. 3453:. 3449:. 3422:. 3414:. 3404:28 3402:. 3379:. 3369:39 3367:. 3344:. 3334:93 3332:. 3309:. 3297:65 3295:. 3291:. 3268:. 3260:. 3250:25 3248:. 3223:18 3221:. 3217:. 3192:27 3190:. 3167:. 3153:. 3149:. 3126:. 3118:. 3108:21 3106:. 3083:. 3075:. 3065:73 3063:. 3040:. 3030:. 3016:. 3012:. 2980:. 2945:. 2921:82 2919:. 2896:. 2888:. 2876:. 2852:. 2844:. 2836:. 2824:. 2801:. 2793:. 2785:. 2777:. 2763:. 2739:. 2731:. 2721:12 2719:. 2675:. 2665:. 2655:11 2653:. 2649:. 2626:. 2616:. 2606:10 2604:. 2600:. 2577:. 2567:56 2565:. 2492:. 2484:. 2474:15 2472:. 2449:. 2439:. 2425:. 2421:. 2398:. 2388:. 2374:. 2370:. 2338:. 2326:15 2324:. 2320:. 2297:. 2285:46 2283:. 2279:. 2234:. 2224:. 2214:. 2202:. 2198:. 2173:83 2171:. 2148:. 2138:. 2128:22 2126:. 2122:. 2099:. 2089:. 2079:. 2069:12 2067:. 2063:. 2040:. 2032:. 2024:. 2014:43 2012:. 2008:. 1985:. 1975:. 1963:. 1959:. 1936:. 1926:. 1912:. 1908:. 1888:^ 1872:20 1870:. 1858:^ 1844:. 1836:. 1828:. 1820:. 1806:. 1781:. 1759:. 1751:. 1739:. 1735:. 1706:. 1702:. 1690:^ 1655:. 1645:22 1643:. 1620:. 1612:. 1600:. 1577:. 1567:. 1555:10 1553:. 1549:. 1526:. 1516:22 1514:. 1484:. 1476:. 1466:33 1464:. 1460:. 1430:. 1418:24 1416:. 1412:. 1385:. 1363:. 1353:. 1343:52 1341:. 1337:. 1318:. 1295:. 1287:. 1275:. 1252:. 1244:. 1236:. 1224:. 1201:. 1191:. 1179:. 1175:. 1152:. 1142:. 1132:45 1130:. 1126:. 1097:^ 1080:. 1058:. 1048:. 1036:32 1034:. 1030:. 1014:^ 993:. 981:66 979:. 975:. 956:^ 934:. 921:^ 851:. 828:. 819:C. 801:. 789:, 782:. 766:, 744:. 736:, 732:, 728:, 666:, 662:, 541:. 347:, 312:. 234:, 197:" 4295:/ 4291:/ 4239:: 4235:/ 4193:/ 4187:/ 4181:/ 4169:: 4148:: 4113:: 3911:/ 3893:/ 3805:" 3750:e 3743:t 3736:v 3671:. 3657:: 3630:. 3606:: 3600:7 3579:. 3559:: 3536:. 3516:: 3493:. 3469:: 3461:: 3455:9 3443:" 3430:. 3410:: 3387:. 3375:: 3352:. 3340:: 3317:. 3303:: 3276:. 3256:: 3233:. 3202:. 3198:: 3175:. 3161:: 3134:. 3114:: 3091:. 3071:: 3048:. 3024:: 3018:5 2997:. 2957:. 2931:. 2904:. 2884:: 2860:. 2840:: 2832:: 2809:. 2789:: 2781:: 2771:: 2747:. 2727:: 2704:. 2683:. 2661:: 2634:. 2612:: 2585:. 2573:: 2550:. 2525:. 2500:. 2480:: 2457:. 2433:: 2406:. 2382:: 2376:9 2346:. 2332:: 2305:. 2291:: 2242:. 2218:: 2210:: 2204:5 2183:. 2156:. 2134:: 2107:. 2083:: 2075:: 2048:. 2020:: 1993:. 1971:: 1965:7 1944:. 1920:: 1914:8 1898:" 1882:. 1852:. 1832:: 1824:: 1814:: 1791:. 1767:. 1747:: 1741:1 1720:. 1714:: 1708:7 1684:. 1663:. 1651:: 1628:. 1608:: 1585:. 1561:: 1534:. 1522:: 1499:. 1472:: 1445:. 1424:: 1397:. 1371:. 1349:: 1320:9 1303:. 1283:: 1277:9 1260:. 1240:: 1232:: 1209:. 1187:: 1181:2 1160:. 1138:: 1091:. 1066:. 1052:: 1042:: 1008:. 987:: 950:. 395:( 221:( 193:"

Index


Scientific classification
Edit this classification
Bacteria
Actinomycetota
Actinomycetia
Propionibacteriales
Propionibacteriaceae
Cutibacterium
Binomial name
subsp. acnes
subsp. defendens
subsp. elongatum
Synonyms
aerotolerant
anaerobic
gram-positive
bacterium
skin
acne
blepharitis
endophthalmitis
intraocular surgery
genome
genes
enzymes
skin
proteins
immune system
commensal

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