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Clindamycin

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1608: 727: 704: 1669: 40: 1037: 31: 1764: 8224: 1209: 1275:, one with clindamycin) are placed 15–20 mm apart on the plate. If the area of inhibition around the clindamycin disk is D-shaped, the test result is positive. Despite the apparent susceptibility to clindamycin in the absence of erythromycin, a positive D-test precludes therapeutic use of clindamycin. This is because the erythromycin-inducible 1482:. Common adverse drug reactions associated with topical formulations – found in over 10% of people – include: dryness, burning, itching, scaliness, or peeling of skin (lotion, solution); erythema (foam, lotion, solution); oiliness (gel, lotion). Additional side effects include 1861:, for which it is the preferred drug in dogs and cats. They can be used both by mouth and topically. A disadvantage is that bacterial resistance can develop fairly quickly. Gastrointestinal upset may also occur. Toxoplasmosis rarely causes symptoms in cats, but can do so in very young or 4561:
Cunliffe WJ, Holland KT, Bojar R, Levy SF (2002). "A randomized, double-blind comparison of a clindamycin phosphate/benzoyl peroxide gel formulation and a matching clindamycin gel with respect to microbiologic activity and clinical efficacy in the topical treatment of acne vulgaris".
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group of lincomycin. The synthesis of clindamycin was first announced by BJ Magerlein, RD Birkenmeyer, and F Kagan on the fifth Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in 1966. It has been on the market since 1968.
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Jeddi A, Azaiez A, Bouguila H, Kaoueche M, Malouche S, Daghfous F, et al. (1997). "Intérêt de la clindamycine dans le traitement de la toxoplasmose oculaire" [Value of clindamycin in the treatment of ocular toxoplasmosis].
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Beauduy CE, Winston LG. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidinones. In: Katzung BG. eds. Basic & Clinical Pharmacology, 14e New York, NY: McGraw-Hill;
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Mitrano JA, Spooner LM, Belliveau P (September 2009). "Excretion of antimicrobials used to treat methicillin-resistant Staphylococcus aureus infections during lactation: safety in breastfeeding infants".
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Schlünzen F, Zarivach R, Harms J, Bashan A, Tocilj A, Albrecht R, et al. (October 2001). "Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria".
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Di Bella S, Antonello RM, Sanson G, Maraolo AE, Giacobbe DR, Sepulcri C, et al. (June 2022). "Anaerobic bloodstream infections in Italy (ITANAEROBY): A 5-year retrospective nationwide survey".
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Seidler EM, Kimball AB (July 2010). "Meta-analysis comparing efficacy of benzoyl peroxide, clindamycin, benzoyl peroxide with salicylic acid, and combination benzoyl peroxide/clindamycin in acne".
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to chloroquine is common. Clindamycin should not be used as an antimalarial by itself, although it appears to be very effective as such, because of its slow action. Patient-derived isolates of
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hydrochloride). Oral suspension is not favored for administration of clindamycin to children, due to its extremely foul taste and odor. Clindamycin is formulated in a vaginal cream and as
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InChI=1S/C18H33ClN2O5S/c1-5-6-10-7-11(21(3)8-10)17(25)20-12(9(2)19)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,22-24H,5-8H2,1-4H3,(H,20,25)/t9-,10+,11-,12+,13-,14+,15+,16+,18+/m0/s1
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Coyle EA (May 2003). "Targeting bacterial virulence: the role of protein synthesis inhibitors in severe infections. Insights from the Society of Infectious Diseases Pharmacists".
1341:(MRSA). Many strains of MRSA are still susceptible to clindamycin; however, in the United States spreading from the West Coast eastwards, MRSA is becoming increasingly resistant. 2642: 8158: 1834:
are manufactured by Olive Health Care and sold as Clinsup-V. In Egypt, vaginal cream containing clindamycin produced by Biopharmgroup sold as Vagiclind indicated for vaginosis.
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Brook I, Lewis MA, Sándor GK, Jeffcoat M, Samaranayake LP, Vera Rojas J (November 2005). "Clindamycin in dentistry: more than just effective prophylaxis for endocarditis?".
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Gemmell CG, O'Dowd A (1983). "Regulation of protein A biosynthesis in Staphylococcus aureus by certain antibiotics: its effect on phagocytosis by leukocytes".
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about fourfold and thus is only recommended for use when other antibiotics are not appropriate. It appears to be generally safe in pregnancy. It is of the
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malaria; the latter combination is particularly useful for children, and is the treatment of choice for pregnant women who become infected in areas where
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causing the inducible activity to switch to constitutive (permanently switched on). This in turn, may lead to the therapeutic failure of clindamycin.
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Common side effects include nausea and vomiting, diarrhea, skin rashes, and pain at the site of injection. It increases the risk of hospital-acquired
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When testing a gram-positive culture for sensitivity to clindamycin, it is common to perform a "D-test" to determine if there is a sub-population of
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Several combination acne treatments containing clindamycin are also marketed, such as single-product formulations of clindamycin with
1486:. Common side effects – found in over 10% of people – in vaginal applications include fungal infection. 7868: 7474: 7389: 2656: 2456: 1526:
is a potentially lethal condition commonly associated with clindamycin, but which also occurs with other antibiotics. Overgrowth of
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Daum RS (July 2007). "Clinical practice. Skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus".
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group of antibiotics, however, the resistance mechanism is only induced by the presence of 14-membered ring macrolides, such as
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Birkenmeyer RD, Kagan F (July 1970). "Lincomycin. XI. Synthesis and structure of clindamycin, a potent antibacterial agent".
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Clindamycin is white or yellow powder that is very soluble in water. The topically used clindamycin phosphate is a phosphate-
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associated with systemic clindamycin therapy – found in over 1% of people – include: diarrhea,
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If the area of inhibition around the clindamycin disk is circular, the test result is negative and clindamycin can be used.
4438:"Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance" 1799:) and a solution in ethanol (containing clindamycin hydrochloride) and is used primarily as a prescription acne treatment. 1052:
plus benzoyl peroxide. Topical clindamycin plus topical benzoyl peroxide is more effective than topical clindamycin alone.
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to clindamycin, results in the production of a toxin that causes a range of adverse effects, from diarrhea to colitis and
3231:"Potentiation of opsonization and phagocytosis of Streptococcus pyogenes following growth in the presence of clindamycin" 2544: 1528: 4608: 3802:
Breastfeeding and maternal medication : recommendations for drugs in the Eleventh WHO Model List of Essential Drugs
8264: 4761: 3059:"Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites" 867: 177: 1363:. The rationale for this approach is a presumed synergy between vancomycin, which causes the death of the bacteria by 6800: 4718: 4680: 3852: 3235: 2313: 2253: 2039: 836: 1489:
Rarely – in less than 0.1% of people – clindamycin therapy has been associated with
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by staphylococci; it may also induce changes in the surface structure of bacteria that make them more sensitive to
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Fogdall RP, Miller RD (1974). "Prolongation of a pancuronium-induced neuromuscular blockade by clindamycin".
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Jolivet-Gougeon A, Sixou JL, Tamanai-Shacoori Z, Bonnaure-Mallet M (April 2007). "Antimicrobial treatment of
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Saunte DM, Jemec GB (November 2017). "Hidradenitis Suppurativa: Advances in Diagnosis and Treatment".
971:. In 2021, it was the 118th most commonly prescribed medication in the United States, with more than 5 6873: 6385: 5120: 4693: 4655: 2273: 1895: 1707:
antibiotics, among others. The binding is reversible. Clindamycin is more effective than lincomycin.
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The X-ray crystal structures of clindamycin bound to ribosomes (or ribosomal subunits) derived from
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bacteria, as well. It is also used to treat bone and joint infections, particularly those caused by
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Matzov D, Eyal Z, Benhamou RI, Shalev-Benami M, Halfon Y, Krupkin M, et al. (September 2017).
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Wilson DN (January 2014). "Ribosome-targeting antibiotics and mechanisms of bacterial resistance".
2153:"Antibiotics and hospital-acquired Clostridium difficile-associated diarrhoea: a systematic review" 1822:), and Acanya, among other trade names—and, in the United States, a combination of clindamycin and 1641: 1523: 1455: 1439: 5648: 4630: 1563:. A 2009 review found it was likely safe in breastfeeding mothers, but did find one complication ( 7162: 7024: 7001: 6768: 6441: 5601: 5149: 4705: 4667: 1718: 214: 106: 7680: 7309: 7012: 6888: 6844: 6560: 6500: 5787: 5373: 5310: 3377:
Pleyer U, Torun N, Liesenfeld O (2007). "Okuläre Toxoplasmose" [Ocular toxoplasmosis].
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Gemmell CG, Peterson PK, Schmeling D, Kim Y, Mathews J, Wannamaker L, et al. (May 1981).
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from the Peruvian Amazon have been reported to be resistant to clindamycin as evidenced by
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plate is inoculated with the bacteria in question and two drug-impregnated disks (one with
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Woods CR (December 2009). "Macrolide-inducible resistance to clindamycin and the D-test".
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uses of clindamycin are quite similar to its human indications, and include treatment of
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For the treatment of acne, in the long term, the combined use of topical clindamycin and
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Annane D, Clair B, Salomon J (2004). "Managing toxic shock syndrome with antibiotics".
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Dharia NV, Plouffe D, Bopp SE, González-Páez GE, Lucas C, Salas C, et al. (2010).
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means they should not be given simultaneously, as this causes antagonism and possible
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resistance to clindamycin. This is because of the activity of the macrolide-inducible
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Magerlein BJ, Birkenmeyer RD, Kagan F (1966). "Chemical modification of lincomycin".
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Kelly CP, Pothoulakis C, LaMont JT (January 1994). "Clostridium difficile colitis".
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It is most effective against infections involving the following types of organisms:
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Spízek J, Rezanka T (May 2004). "Lincomycin, clindamycin and their applications".
4148: 4024:"Prolongation of rapacuronium neuromuscular blockade by clindamycin and magnesium" 3344: 3327: 3283:
Lamont RF (2005). "Can antibiotics prevent preterm birth—the pro and con debate".
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application of clindamycin phosphate can be used to treat mild to moderate acne.
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The combination of clindamycin and quinine is the standard treatment for severe
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form, as a lotion, and in a foam delivery system (each containing clindamycin
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World Health Organization model list of essential medicines: 22nd list (2021)
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effect. At higher concentrations, it may be bactericidal. It is a bacterial
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Homer MJ, Aguilar-Delfin I, Telford SR, Krause PJ, Persing DH (July 2000).
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Clindamycin, either applied to skin or taken by mouth, may also be used in
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for "DARE-BV1 in the Treatment of Bacterial Vaginosis (DARE-BVFREE)" at
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during early pregnancy to about a third of the risk of untreated women.
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have been determined; the structure of the closely related antibiotic
942:, and as a cream or a gel to be applied to the skin or in the vagina. 39: 8068: 8058: 8053: 8043: 8028: 8013: 7958: 7913: 7883: 7745: 7725: 7650: 7590: 7585: 7454: 7384: 7374: 7319: 6959: 6908: 6857: 6832: 6821: 6747: 6716: 6522: 6204: 6164: 6151: 6084: 6079: 6069: 6064: 6059: 5890: 5845: 5808: 5803: 5774: 5764: 5754: 5580: 5519: 5423: 5400: 5301: 5291: 5079: 5038: 5018: 4993: 4975: 4874: 4406: 3628:"Clostridium difficile associated diarrhoea: diagnosis and treatment" 1796: 1780: 1704: 1685: 1588: 1494: 1280: 1229: 1221: 1156: 908: 502: 437: 432: 130: 4133:"Microbiological and Pharmacological Behavior of 7-Chlorolincomycin" 3759:
American Academy of Pediatrics Committee on Drugs (September 2001).
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Neonatal Formulary: Drug Use in Pregnancy and the First Year of Life
1014:, clindamycin may be used to treat infections caused by susceptible 7973: 7953: 7923: 7795: 7755: 7605: 7595: 7469: 6289: 5759: 5730: 5514: 5488: 5069: 5064: 5010: 4988: 4603: 2900: 2884: 2867: 2194:"Current indications for the use of clindamycin: A critical review" 1692: 1649: 1502: 1463: 1384: 1373: 1217: 991: 604: 596: 527: 172: 3847:. Rowe, Hilary E. (Seventeenth ed.). New York, NY: Springer. 1551:
Clindamycin is classified as compatible with breastfeeding by the
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Use of clindamycin during pregnancy is generally considered safe.
801: 671: 8183: 8168: 8098: 7560: 7284: 7101: 6742: 6274: 5570: 5282: 5074: 4947: 4907: 4879: 2484:"Antibiotic treatment of gram-positive bone and joint infections" 1467: 1392: 1379: 1299: 1257: 935: 931: 233: 3712:"Clindamycin as an antimalarial drug: review of clinical trials" 3325: 3018:"Treatment of malaria in the United States: a systematic review" 2954:"Clindamycin as an antimalarial drug: review of clinical trials" 1036: 6371: 4484: 1637: 1459: 1180:
susceptibility data for a few medically significant pathogens.
635: 441: 6991: 3056: 2677: 2098:"Clindamycin phosphate- clindamycin phosphate gel usp, 1% gel" 1763: 30: 1827: 1657: 1471: 1368: 1364: 1091: 1068: 792: 615: 412: 4703:, in Kahn, Cynthia M., Line, Scott, Aiello, Susan E. (ed.): 4665:, in Kahn, Cynthia M., Line, Scott, Aiello, Susan E. (ed.): 4384: 688: 3419: 3228: 2522: 1811: 1684:
by inhibiting ribosomal translocation, in a similar way to
1475: 1348:, such use is generally not recommended due to resistance. 1268: 587: 84: 75: 7221: 2306:
Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition
1302:, clindamycin is effective and well tolerated in treating 6031: 5682: 4179: 2565: 2272: 1903: 1815: 1792: 1771:
Clindamycin preparations that are taken by mouth include
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studies have shown clindamycin reduces the production of
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Feldman S, Careccia RE, Barham KL, Hancox J (May 2004).
2417: 2248:(7 ed.). John Wiley & Sons. 2014. p. 162. 1173:, for which clindamycin is a first-line drug of choice. 4326:
Dunkle JA, Xiong L, Mankin AS, Cate JH (October 2010).
3875: 3761:"Transfer of drugs and other chemicals into human milk" 3576: 3015: 965:
World Health Organization's List of Essential Medicines
3674: 8212: 4325: 4130: 3376: 2769:. In Root RE, Waldvogel F, Corey L, Stamm WE (eds.). 2000:. The American Society of Health-System Pharmacists. 1791:. It is also available for topical administration in 1688:. It does so by binding to the rRNA of the bacterial 1478:. High doses (both intravenous and oral) may cause a 994:, including dental infections, and infections of the 465:
methyl 7-chloro-6,7,8-trideoxy-6-{amino}-1-thio-
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Clindamycin has been proven to decrease the risk of
1367:, and clindamycin, which is a powerful inhibitor of 956:
and works by blocking bacteria from making protein.
72: 63: 2773:. Oxford: Oxford University Press. pp. 291–7. 1950: 1948: 1888: 1695:subunit, overlapping with the binding sites of the 81: 78: 4435: 3804:. Geneva, Switzerland: World Health Organization. 3107: 2771:Clinical infectious diseases: a practical approach 2643:"Lincosamides, Oxazolidinones, and Streptogramins" 2566:Oge' LK, Broussard A, Marshall MD (October 2019). 1875: 1228:. This phenotype of bacteria are resistant to the 4436:Tu D, Blaha G, Moore PB, Steitz TA (April 2005). 3193: 3016:Griffith KS, Lewis LS, Mali S, Parise ME (2007). 887:medication used for the treatment of a number of 8236: 4095: 3577:de Groot MC, van Puijenbroek EP (October 2007). 2420:Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1945: 515: 4332:Proceedings of the National Academy of Sciences 2561: 2559: 2557: 1779:) and oral suspensions (containing clindamycin 1587:. Its similarity to the mechanism of action of 490: 4776: 4263:University of Michigan. Retrieved 31 July 2009 2764: 2599: 2481: 2308:. Jones & Bartlett Learning. p. 108. 1543: 8275:World Health Organization essential medicines 7207: 6486: 5634: 5194: 4762: 4537:Infectious Diseases in Critical Care Medicine 4217: 3980: 3945: 1136:Most aerobic Gram-negative bacteria (such as 4599:"FDA Approvals: Ziana, Kadian, Polyphenon E" 3983:"Clindamycin-induced neuromuscular blockade" 3799: 3709: 2951: 2554: 1509:, renal dysfunction, cardiac arrest, and/or 1428:, is effective in treating mild to moderate 176: 7490: 3927:. National Library of Medicine (US). 2006. 3508: 3011: 3009: 2947: 2945: 2943: 2941: 2198:The Canadian Journal of Infectious Diseases 1516: 1160:) are resistant to clindamycin, as are the 7541:Allopregnanedione (5α-dihydroprogesterone) 7214: 7200: 6493: 6479: 6102: 5641: 5627: 5201: 5187: 4769: 4755: 4021: 2595: 2593: 2451: 2449: 2299: 2297: 2057: 2055: 1992: 1990: 1988: 1986: 1984: 1982: 1980: 1978: 1976: 1351:Clindamycin is used in cases of suspected 1199:: <0.015 μg/mL – >64 μg/mL 725: 702: 555: 4510: 4453: 4361: 4351: 4156: 4131:Meyers BR, Kaplan K, Weinstein L (1969). 4061: 4059: 4039: 3998: 3776: 3735: 3651: 3602: 3485: 3475: 3353: 3343: 3278: 3276: 3256: 3084: 3033: 2989: 2971: 2883: 2699: 2499: 2285: 2219: 2209: 2168: 2146: 2144: 2023: 2021: 2019: 575: 7239:Tooltip Constitutive androstane receptor 4554: 4067:"Clindamycin Phosphate Topical Solution" 3974: 3583:British Journal of Clinical Pharmacology 3552: 3550: 3548: 3006: 2938: 2912:The Pediatric Infectious Disease Journal 2637: 2635: 2633: 2631: 2568:"Acne Vulgaris: Diagnosis and Treatment" 2303: 2151:Thomas C, Stevenson M, Riley TV (2003). 1925:"Product monograph brand safety updates" 1762: 1667: 1606: 1207: 1035: 959:Clindamycin was first made in 1966 from 824:Cl(C)(NC(=O)1N(C)C(CCC)C1)2O(SC)(O)(O)2O 4596: 4527: 3939: 3455: 2865: 2729: 2727: 2590: 2516: 2457:"Cleocin I.V. Indications & Dosage" 2446: 2330:"Competitive Generic Therapy Approvals" 2294: 2266: 2052: 1973: 1623:, a natural antibiotic produced by the 1575:Clindamycin may prolong the effects of 1244:. During a D-test, bacteria of the iMLS 1193:: 0.002 μg/mL – >256 μg/mL 1187:: 0.016 μg/mL – >256 μg/mL 1126:, although resistance is increasing in 1055: 983:Clindamycin is used primarily to treat 698: 535: 149: 8237: 7994:Pregnanedione (5β-dihydroprogesterone) 7380:Pregnanedione (5β-dihydroprogesterone) 5101:Clindamycin/adapalene/benzoyl peroxide 4631:"Generic Cleocin Vaginal Availability" 4272: 4220:Applied Microbiology and Biotechnology 4124: 4056: 3925:Drugs and Lactation Database (LactMed) 3370: 3282: 3273: 3101: 3050: 2736:"Clindamycin: new look at an old drug" 2475: 2262:from the original on 8 September 2017. 2191: 2185: 2141: 2048:from the original on 8 September 2017. 2027: 2016: 1883:Use During Pregnancy and Breastfeeding 1741: 1732:bound to the 50S ribosomal subunit of 1663: 1420:Clindamycin may also be used to treat 1330:Clindamycin may be useful in skin and 1040:Clindamycin phosphate topical solution 716: 345: 7195: 6474: 5622: 5182: 4750: 4533: 4213: 4211: 4209: 4207: 4205: 4203: 4182:Antimicrobial Agents and Chemotherapy 4015: 3716:Antimicrobial Agents and Chemotherapy 3625: 3619: 3572: 3570: 3556: 3545: 3463:Antimicrobial Agents and Chemotherapy 3413: 3319: 3150: 2959:Antimicrobial Agents and Chemotherapy 2909: 2648:Merck Manual of Diagnosis and Therapy 2628: 2394:"Clindamycin - Drug Usage Statistics" 2280:. Geneva: World Health Organization. 1881: 664: 643: 623: 358: 167: 135: 4611:from the original on 6 February 2011 4077:from the original on 2 February 2017 3842: 2758: 2733: 2724: 2659:from the original on 2 December 2007 2374:from the original on 15 January 2024 2061: 1956:"Xaciato- clindamycin phosphate gel" 670: 294: 284: 274: 264: 121:7-chloro-7-deoxylincomycin, DARE-BV1 3710:Lell B, Kremsner PG (August 2002). 2004:from the original on 12 August 2021 603: 595: 506: 13: 4200: 3567: 2550:from the original on 27 July 2011. 2459:. RxList.com. 2007. Archived from 1758: 111:Cleocin, Clinacin, Dalacin, others 14: 8286: 4728: 3579:"Clindamycin and taste disorders" 2824:10.1016/j.ijantimicag.2006.10.005 2525:"Diagnosis and treatment of acne" 2344:from the original on 29 June 2023 2034:. Berlin: Springer. p. 152. 1844: 321: 199: 8222: 4041:10.1097/00000539-200201000-00023 3960:10.1097/00000542-197410000-00023 3595:10.1111/j.1365-2125.2007.02908.x 3423:Journal Français d'Ophtalmologie 3297:10.1111/j.1471-0528.2005.00589.x 2129:(Press release). 7 December 2021 1559:with breastfeeding according to 1071:, including some members of the 759: 756: 750: 56: 38: 29: 4686: 4648: 4623: 4590: 4478: 4429: 4378: 4319: 4309: 4266: 4254: 4173: 4089: 4034:(1): 123–4, table of contents. 3913: 3869: 3845:Medications & mothers' milk 3836: 3793: 3752: 3728:10.1128/AAC.46.8.2315-2320.2002 3703: 3677:New England Journal of Medicine 3668: 3502: 3449: 3222: 3187: 3144: 2973:10.1128/AAC.46.8.2315-2320.2002 2859: 2838: 2799: 2765:Gold HS, Moellering RC (1999). 2740:Infectious Diseases in Children 2671: 2482:Darley ES, MacGowan AP (2004). 2411: 2386: 2356: 2322: 2236: 1755:and is relatively inexpensive. 1570: 1445: 978: 938:. It is available by mouth, by 919:. It can also be used to treat 849:Key:KDLRVYVGXIQJDK-AWPVFWJPSA-N 7546:Allopregnanolone (brexanolone) 7030:piperaquine/dihydroartemisinin 6142:transpeptidation/translocation 4098:Journal of Medicinal Chemistry 2790:Retrieved 19 January 2009. 2692:10.1016/j.anaerobe.2022.102583 2115: 2090: 1917: 1837:Clindamycin is available as a 1751:Clindamycin is available as a 1553:American Academy of Pediatrics 1355:, often in combination with a 771: 765: 744: 334: 1: 8201:Receptor/signaling modulators 8159:Tropanyl 3,5-dimethulbenzoate 8009:Pregnenolone 16α-carbonitrile 6594:trimethoprim/sulfamethoxazole 5116:Erythromycin/benzoyl peroxide 4721:. Retrieved 14 December 2007. 4694:"Toxoplasmosis: Introduction" 4683:. Retrieved 14 December 2007. 4597:Waknine Y (1 December 2006). 4576:10.1016/S0149-2918(02)80023-6 4149:10.1128/AEM.17.5.653-657.1969 3981:al Ahdal O, Bevan DR (1995). 3560:Australian Medicines Handbook 3345:10.1128/CMR.13.3.451-469.2000 2432:10.1016/j.tripleo.2005.02.086 1868: 1561:Medications and Mothers' Milk 1322:drug susceptibility testing. 915:(middle ear infections), and 6992:Fixed-dose (co-formulated) 5106:Clindamycin/benzoyl peroxide 2952:Lell B, Kremsner PG (2002). 2924:10.1097/INF.0b013e3181c35cc5 2872:Clinical Infectious Diseases 2767:"Macrolides and clindamycin" 2336:Food and Drug Administration 1746: 1676:Clindamycin has a primarily 1602: 1577:neuromuscular-blocking drugs 930:(MRSA). In combination with 7: 7736:Dodecylbenzenesulfonic acid 7495:Tooltip Pregnane X receptor 7223:Xenobiotic-sensing receptor 4706:The Merck Veterinary Manual 4668:The Merck Veterinary Manual 4275:Nature Reviews Microbiology 3689:10.1056/NEJM199401273300406 3165:10.1592/phco.23.5.638.32191 2866:Leclerq R (February 2002). 1682:protein synthesis inhibitor 1544:Pregnancy and breastfeeding 1424:, and, in combination with 901:pelvic inflammatory disease 10: 8291: 5131:Tretinoin/benzoyl peroxide 5096:Adapalene/benzoyl peroxide 4540:. CRC Press. p. 506. 4455:10.1016/j.cell.2005.02.005 4022:Sloan PA, Rasul M (2002). 3935:. Bookshelf ID: NBK501208. 2614:10.1016/j.jaad.2009.07.052 2290:. WHO/MHP/HPS/EML/2021.02. 1507:raised liver enzyme levels 1365:breakdown of the cell wall 1344:While it has been used in 1289: 934:, it can be used to treat 734:Chemical and physical data 8265:Drugs developed by Pfizer 8192: 7488: 7232: 7152: 7128: 7100: 7074: 7038: 6982: 6927: 6887: 6874:sulfadoxine/pyrimethamine 6866: 6843: 6799: 6790: 6756: 6730: 6677: 6666: 6657: 6648: 6639: 6602: 6584: 6559: 6543: 6532: 6521: 6431: 6386:Quinupristin/dalfopristin 6344: 6316: 6288: 6150: 6139: 6093: 6039: 6030: 6004: 5918: 5903: 5883: 5822: 5705: 5690: 5681: 5654:inhibit protein synthesis 5558: 5533: 5505: 5487: 5399: 5390: 5372: 5344: 5300: 5281: 5228: 5139: 5121:Erythromycin/isotretinoin 5088: 5052: 5009: 4946: 4893: 4860: 4827: 4789: 4232:10.1007/s00253-003-1545-7 3391:10.1007/s00347-007-1535-8 3122:10.1517/14656566.5.8.1701 2274:World Health Organization 2192:Smieja M (January 1998). 1629:Streptomyces lincolnensis 1346:intraabdominal infections 1203: 1176:The following represents 1170:Capnocytophaga canimorsus 1167:. A notable exception is 857: 832: 812: 790: 777: 738: 733: 714: 682: 654: 634: 614: 586: 566: 546: 526: 501: 481: 453: 448: 431: 418: 406: 396: 384: 376: 311: 306: 251: 239: 213: 187: 157: 143: 125: 115: 105: 51: 46: 37: 28: 8119:Testosterone isocaproate 8034:Reverse triiodothyronine 5905:Tetracycline antibiotics 4699:20 December 2007 at the 3800:Organization WH (2002). 3644:10.1136/bmj.331.7515.498 3563:. Adelaide: AMH Pty Ltd. 3456:Fishman JA (June 1998). 3110:Expert Opin Pharmacother 3035:10.1001/jama.297.20.2264 2734:Bell EA (January 2005). 2031:Hidradenitis suppurativa 1998:"Clindamycin (Systemic)" 1775:(containing clindamycin 1738:has also been reported. 1660:prodrug of clindamycin. 1529:Clostridioides difficile 1524:Pseudomembranous colitis 1518:Clostridioides difficile 1456:pseudomembranous colitis 1440:hidradenitis suppurativa 1406:in women diagnosed with 1325: 1267:To perform a D-test, an 1191:Streptococcus pneumoniae 7511:17α-Hydroxyprogesterone 7506:17α-Hydroxypregnenolone 7025:artesunate/pyronaridine 7002:artemether/lumefantrine 5602:Lactobacillus fermentum 4353:10.1073/pnas.1007988107 3523:10.1001/jama.2017.16691 2812:Int J Antimicrob Agents 1857:, skin infections, and 1719:Deinococcus radiodurans 1031: 975:million prescriptions. 967:. It is available as a 473:-galacto-octopyranoside 8245:Anti-acne preparations 7013:artesunate/amodiaquine 5311:Diiodohydroxyquinoline 4734:Clinical trial number 4661:7 January 2008 at the 4491:Nucleic Acids Research 3891:10.1592/phco.29.9.1103 3778:10.1542/peds.108.3.776 3196:J Antimicrob Chemother 2488:J Antimicrob Chemother 2157:J Antimicrob Chemother 1768: 1725:Haloarcura marismortui 1673: 1632:. It is obtained by 7( 1612: 1557:L2 probably compatible 1532:, which is inherently 1452:adverse drug reactions 1431:Pneumocystis jirovecii 1336:methicillin-resistant 1248:phenotype demonstrate 1213: 1197:Streptococcus pyogenes 1151:Haemophilus influenzae 1041: 987:caused by susceptible 925:methicillin-resistant 246:Lincosamide antibiotic 7250:6,7-Dimethylesculetin 7047:artesunate/mefloquine 7019:artesunate/mefloquine 5111:Clindamycin/tretinoin 4711:John Wiley & Sons 4673:John Wiley & Sons 4604:Medscape Medical News 3557:Rossi S, ed. (2006). 3477:10.1128/AAC.42.6.1309 3077:10.1101/gr.105163.110 2602:J. Am. Acad. Dermatol 2364:"The Top 300 of 2021" 1766: 1735:Staphylococcus aureus 1672:Clindamycin mechanism 1671: 1611:Clindamycin phosphate 1610: 1338:Staphylococcus aureus 1334:infections caused by 1315:Plasmodium falciparum 1305:Plasmodium falciparum 1252:erythromycin-induced 1211: 1185:Staphylococcus aureus 1162:facultative anaerobic 1039: 1021:Staphylococcus aureus 948:Clostridium difficile 940:injection into a vein 927:Staphylococcus aureus 7837:Hypericum perforatum 7826:Hetacillin potassium 7059:quinine/tetracycline 6731:4-Methanolquinolines 6506:antiprotozoal agents 6095:Peptidyl transferase 5126:Sulfacetamide/sulfur 3208:10.1093/jac/12.6.587 2076:10.1056/NEJMcp070747 1806:—sold as BenzaClin ( 1767:Clindamycin capsules 1353:toxic shock syndrome 1129:Bacteroides fragilis 1056:Susceptible bacteria 985:anaerobic infections 923:, and some cases of 889:bacterial infections 7666:Cyproterone acetate 7566:Amlodipine besylate 7056:quinine/doxycycline 7053:quinine/clindamycin 7041:(not co-formulated) 5724:Dihydrostreptomycin 4966:Cyproterone acetate 4399:2001Natur.413..814S 4344:2010PNAS..10717152D 4287:10.1038/nrmicro3155 4110:10.1021/jm00298a007 2463:on 27 November 2007 2304:Hamilton R (2015). 2211:10.1155/1998/538090 1789:bacterial vaginosis 1742:Society and culture 1664:Mechanism of action 1408:bacterial vaginosis 1106:rod-shaped bacteria 354:(Prescription only) 330:(Prescription only) 119:7-chloro-lincomycin 25: 8139:Thonzonium bromide 7894:Methylprednisolone 7695:prasterone sulfate 7179:Never to phase III 7039:Other combinations 6919:dihydroartemisinin 6701:hydroxychloroquine 6458:Never to phase III 5166:Never to phase III 4814:Blue light therapy 4809:8-Hydroxyquinoline 4780:-treating agents ( 4742:ClinicalTrials.gov 4692:(8 February 2005) 4654:(8 February 2005) 4503:10.1093/nar/gkx658 4000:10.1007/BF03011880 3332:Clin Microbiol Rev 3291:(Suppl 1): 67–73. 2794:Google Book Search 2501:10.1093/jac/dkh191 2170:10.1093/jac/dkg254 2028:Leyden JJ (2006). 1865:kittens and cats. 1769: 1753:generic medication 1674: 1613: 1484:contact dermatitis 1214: 1165:Enterobacteriaceae 1042: 969:generic medication 913:acute otitis media 21: 8210: 8209: 7844:Indinavir sulfate 7551:Alpha-Lipoic acid 7526:Δ-Androstenedione 7516:Δ-Androstenedione 7189: 7188: 7124: 7123: 7096: 7095: 7092: 7091: 7070: 7069: 7066: 7065: 6978: 6977: 6883: 6882: 6786: 6785: 6635: 6634: 6561:Cryptosporidiosis 6468: 6467: 6427: 6426: 6423: 6422: 6135: 6134: 6026: 6025: 6022: 6021: 5931:Chlortetracycline 5899: 5898: 5616: 5615: 5554: 5553: 5176: 5175: 4885:Red light therapy 4862:Anti-inflammatory 4547:978-1-4200-9241-7 4534:Cunha BA (2009). 3638:(7515): 498–501. 3249:10.1172/JCI110152 2780:978-0-19-508103-9 2746:on 8 October 2011 1863:immunocompromised 1787:for treatment of 1615:Clindamycin is a 1279:gene is prone to 1220:present with the 1108:, including some 1006:. In people with 996:respiratory tract 954:lincosamide class 875: 874: 803:Interactive image 684:CompTox Dashboard 472: 468: 362: 349: 337: 325: 203: 170: 8282: 8227: 8226: 8225: 8218: 8129:Thiamylal sodium 7864:γ-linolenic acid 7860:α-Linolenic acid 7858:Linolenic acid: 7849:Lasalocid sodium 7839:(St John's wort) 7731:Docusate calcium 7661:Cyclophosphamide 7536:Allopregnanediol 7521:Δ-Androstenediol 7496: 7492: 7450:Ethinylestradiol 7300:Cyclophosphamide 7240: 7236: 7216: 7209: 7202: 7193: 7192: 6989: 6988: 6797: 6796: 6675: 6674: 6664: 6663: 6655: 6654: 6646: 6645: 6557: 6556: 6541: 6540: 6530: 6529: 6512:antiparasitics ( 6495: 6488: 6481: 6472: 6471: 6148: 6147: 6100: 6099: 6037: 6036: 5986:Rolitetracycline 5916: 5915: 5703: 5702: 5688: 5687: 5643: 5636: 5629: 5620: 5619: 5546:Methylrosaniline 5397: 5396: 5203: 5196: 5189: 5180: 5179: 4999:Ethinylestradiol 4852:Benzoyl peroxide 4804:Benzoyl peroxide 4771: 4764: 4757: 4748: 4747: 4722: 4690: 4684: 4652: 4646: 4645: 4643: 4641: 4627: 4621: 4620: 4618: 4616: 4594: 4588: 4587: 4558: 4552: 4551: 4531: 4525: 4524: 4514: 4497:(17): 10284–92. 4482: 4476: 4475: 4457: 4433: 4427: 4426: 4407:10.1038/35101544 4393:(6858): 814–21. 4382: 4376: 4375: 4365: 4355: 4338:(40): 17152–57. 4323: 4317: 4313: 4307: 4306: 4270: 4264: 4258: 4252: 4251: 4215: 4198: 4197: 4177: 4171: 4170: 4160: 4128: 4122: 4121: 4093: 4087: 4086: 4084: 4082: 4063: 4054: 4053: 4043: 4019: 4013: 4012: 4002: 3978: 3972: 3971: 3943: 3937: 3936: 3917: 3911: 3910: 3873: 3867: 3866: 3843:Hale TW (2017). 3840: 3834: 3833: 3827: 3823: 3821: 3813: 3797: 3791: 3790: 3780: 3756: 3750: 3749: 3739: 3707: 3701: 3700: 3672: 3666: 3665: 3655: 3626:Starr J (2005). 3623: 3617: 3616: 3606: 3574: 3565: 3564: 3554: 3543: 3542: 3506: 3500: 3499: 3489: 3479: 3453: 3447: 3446: 3417: 3411: 3410: 3374: 3368: 3367: 3357: 3347: 3323: 3317: 3316: 3280: 3271: 3270: 3260: 3226: 3220: 3219: 3191: 3185: 3184: 3148: 3142: 3141: 3105: 3099: 3098: 3088: 3054: 3048: 3047: 3037: 3013: 3004: 3003: 2993: 2975: 2949: 2936: 2935: 2907: 2898: 2897: 2887: 2863: 2857: 2856: 2850: 2842: 2836: 2835: 2803: 2797: 2791: 2788: 2783:. Archived from 2762: 2756: 2755: 2753: 2751: 2742:. Archived from 2731: 2722: 2721: 2703: 2675: 2669: 2668: 2666: 2664: 2639: 2626: 2625: 2597: 2588: 2587: 2572:Am Fam Physician 2563: 2552: 2551: 2549: 2529:Am Fam Physician 2520: 2514: 2513: 2503: 2479: 2473: 2472: 2470: 2468: 2453: 2444: 2443: 2415: 2409: 2408: 2406: 2404: 2390: 2384: 2383: 2381: 2379: 2360: 2354: 2353: 2351: 2349: 2340:. 29 June 2023. 2326: 2320: 2319: 2301: 2292: 2291: 2289: 2270: 2264: 2263: 2240: 2234: 2233: 2223: 2213: 2189: 2183: 2182: 2172: 2148: 2139: 2138: 2136: 2134: 2119: 2113: 2112: 2110: 2108: 2094: 2088: 2087: 2059: 2050: 2049: 2025: 2014: 2013: 2011: 2009: 1994: 1971: 1970: 1968: 1966: 1952: 1943: 1942: 1940: 1938: 1921: 1915: 1914: 1912: 1910: 1900:nctr-crs.fda.gov 1892: 1886: 1885: 1879: 1804:benzoyl peroxide 1713:Escherichia coli 1597:cross-resistance 1404:premature births 1371:synthesis. Both 1046:benzoyl peroxide 1008:hypersensitivity 974: 897:joint infections 871: 870: 863: 805: 785: 773: 767: 761: 758: 752: 746: 729: 718: 707: 706: 692: 690: 674: 668: 647: 627: 607: 599: 579: 559: 539: 519: 509: 508: 494: 470: 466: 423: 367: 360: 357: 347: 344: 336: 333: 323: 320: 298: 288: 278: 268: 201: 198: 180: 169: 166: 153: 139: 100: 99: 96: 95: 92: 89: 86: 83: 80: 77: 74: 71: 68: 65: 62: 42: 33: 26: 24: 20: 8290: 8289: 8285: 8284: 8283: 8281: 8280: 8279: 8260:Organochlorides 8235: 8234: 8233: 8223: 8221: 8213: 8211: 8206: 8188: 8089:Suberoylanilide 7806:Fluorometholone 7701:Dibunate sodium 7581:Aurothioglucose 7494: 7484: 7420:3,17β-Estradiol 7238: 7228: 7220: 7190: 7185: 7184: 7169:Clinical trials 7148: 7131: 7120: 7103: 7088: 7062: 7040: 7034: 6984: 6974: 6923: 6890: 6879: 6862: 6839: 6801:DHFR inhibitors 6782: 6752: 6726: 6679:Aminoquinolines 6669: 6659: 6631: 6598: 6580: 6548: 6535: 6524: 6517: 6499: 6469: 6464: 6463: 6448:Clinical trials 6419: 6405:Streptogramin B 6400:Streptogramin A 6340: 6312: 6284: 6131: 6112:Chloramphenicol 6089: 6043: 6018: 6000: 5981:Penimepicycline 5976:Oxytetracycline 5907: 5895: 5879: 5818: 5694: 5692:Aminoglycosides 5677: 5647: 5617: 5612: 5591:Povidone-iodine 5550: 5529: 5501: 5483: 5386: 5368: 5340: 5296: 5277: 5253:Oxytetracycline 5243:Chloramphenicol 5224: 5213:anti-infectives 5207: 5177: 5172: 5171: 5156:Clinical trials 5135: 5084: 5048: 5005: 4942: 4889: 4856: 4823: 4785: 4775: 4731: 4726: 4725: 4701:Wayback Machine 4691: 4687: 4663:Wayback Machine 4656:"Osteomyelitis" 4653: 4649: 4639: 4637: 4629: 4628: 4624: 4614: 4612: 4595: 4591: 4559: 4555: 4548: 4532: 4528: 4483: 4479: 4434: 4430: 4383: 4379: 4324: 4320: 4314: 4310: 4271: 4267: 4259: 4255: 4216: 4201: 4178: 4174: 4129: 4125: 4094: 4090: 4080: 4078: 4065: 4064: 4057: 4020: 4016: 3979: 3975: 3944: 3940: 3919: 3918: 3914: 3879:Pharmacotherapy 3874: 3870: 3855: 3841: 3837: 3825: 3824: 3815: 3814: 3798: 3794: 3757: 3753: 3708: 3704: 3673: 3669: 3624: 3620: 3575: 3568: 3555: 3546: 3517:(20): 2019–32. 3507: 3503: 3454: 3450: 3418: 3414: 3375: 3371: 3324: 3320: 3281: 3274: 3227: 3223: 3192: 3188: 3153:Pharmacotherapy 3149: 3145: 3106: 3102: 3071:(11): 1534–44. 3064:Genome Research 3055: 3051: 3028:(20): 2264–77. 3014: 3007: 2950: 2939: 2908: 2901: 2864: 2860: 2848: 2844: 2843: 2839: 2804: 2800: 2789: 2787:on 13 May 2018. 2781: 2763: 2759: 2749: 2747: 2732: 2725: 2676: 2672: 2662: 2660: 2653:Merck & Co. 2641: 2640: 2629: 2598: 2591: 2564: 2555: 2547: 2521: 2517: 2480: 2476: 2466: 2464: 2455: 2454: 2447: 2416: 2412: 2402: 2400: 2392: 2391: 2387: 2377: 2375: 2362: 2361: 2357: 2347: 2345: 2328: 2327: 2323: 2316: 2302: 2295: 2271: 2267: 2256: 2242: 2241: 2237: 2190: 2186: 2149: 2142: 2132: 2130: 2127:Daré Bioscience 2121: 2120: 2116: 2106: 2104: 2096: 2095: 2091: 2064:N. Engl. J. Med 2060: 2053: 2042: 2026: 2017: 2007: 2005: 1996: 1995: 1974: 1964: 1962: 1954: 1953: 1946: 1936: 1934: 1923: 1922: 1918: 1908: 1906: 1894: 1893: 1889: 1880: 1876: 1871: 1847: 1761: 1759:Available forms 1749: 1744: 1666: 1625:actinobacterium 1605: 1593:chloramphenicol 1581:succinylcholine 1573: 1546: 1538:toxic megacolon 1521: 1448: 1328: 1292: 1247: 1238:streptogramin B 1227: 1206: 1058: 1048:was similar to 1034: 981: 972: 963:. It is on the 866: 864: 861:(what is this?) 858: 853: 850: 845: 840: 839: 828: 825: 820: 819: 808: 783: 770: 764: 755: 749: 710: 686: 678: 650: 630: 610: 582: 562: 542: 522: 505: 497: 477: 474: 461: 460: 421: 398:Protein binding 391: 386:Bioavailability 378:Pharmacokinetic 372: 365: 302: 216: 209: 190: 183: 120: 59: 55: 17: 12: 11: 5: 8288: 8278: 8277: 8272: 8267: 8262: 8257: 8252: 8247: 8232: 8231: 8208: 8207: 8205: 8204: 8197: 8193: 8190: 8189: 8187: 8186: 8181: 8172: 8171: 8166: 8161: 8156: 8154:Troleandomycin 8151: 8146: 8141: 8136: 8131: 8126: 8121: 8116: 8111: 8106: 8101: 8096: 8091: 8086: 8081: 8076: 8074:Spironolactone 8071: 8066: 8061: 8056: 8051: 8046: 8041: 8036: 8031: 8026: 8021: 8016: 8011: 8006: 8001: 7996: 7991: 7986: 7981: 7976: 7971: 7966: 7961: 7956: 7951: 7946: 7944:Norelgestromin 7941: 7936: 7931: 7926: 7921: 7916: 7911: 7906: 7901: 7896: 7891: 7886: 7881: 7876: 7871: 7866: 7856: 7851: 7846: 7841: 7833: 7828: 7823: 7818: 7813: 7808: 7803: 7801:Flucloxacillin 7798: 7793: 7788: 7783: 7778: 7773: 7768: 7763: 7758: 7753: 7748: 7743: 7738: 7733: 7728: 7723: 7718: 7713: 7708: 7703: 7698: 7688: 7678: 7673: 7668: 7663: 7658: 7656:Corticosterone 7653: 7648: 7643: 7638: 7633: 7628: 7623: 7621:Chlorpromazine 7618: 7613: 7608: 7603: 7598: 7593: 7588: 7583: 7578: 7573: 7568: 7563: 7558: 7553: 7548: 7543: 7538: 7533: 7528: 7523: 7518: 7513: 7508: 7499: 7497: 7486: 7485: 7483: 7482: 7477: 7472: 7467: 7462: 7457: 7452: 7447: 7442: 7440:17-Androstanol 7437: 7435:3β-Androstanol 7432: 7430:3α-Androstenol 7427: 7425:3α-Androstanol 7422: 7413: 7412: 7407: 7402: 7397: 7392: 7387: 7382: 7377: 7372: 7367: 7362: 7357: 7352: 7347: 7342: 7337: 7332: 7327: 7322: 7317: 7307: 7302: 7297: 7292: 7287: 7282: 7280:Chlorpromazine 7277: 7272: 7267: 7262: 7257: 7252: 7243: 7241: 7230: 7229: 7219: 7218: 7211: 7204: 7196: 7187: 7186: 7183: 7182: 7181: 7180: 7177: 7166: 7160: 7154: 7153: 7150: 7149: 7147: 7146: 7140:Blastocystosis 7136: 7134: 7126: 7125: 7122: 7121: 7119: 7118: 7108: 7106: 7098: 7097: 7094: 7093: 7090: 7089: 7087: 7086: 7080: 7078: 7072: 7071: 7068: 7067: 7064: 7063: 7061: 7060: 7057: 7054: 7051: 7048: 7044: 7042: 7036: 7035: 7033: 7032: 7027: 7022: 7016: 7010: 7004: 6998: 6996: 6986: 6980: 6979: 6976: 6975: 6973: 6972: 6967: 6962: 6957: 6952: 6947: 6942: 6931: 6929: 6925: 6924: 6922: 6921: 6916: 6911: 6906: 6901: 6895: 6893: 6885: 6884: 6881: 6880: 6878: 6877: 6870: 6868: 6867:Co-formulation 6864: 6863: 6861: 6860: 6855: 6849: 6847: 6841: 6840: 6838: 6837: 6836: 6835: 6830: 6828:chlorproguanil 6817: 6816: 6811: 6805: 6803: 6794: 6788: 6787: 6784: 6783: 6781: 6780: 6774: 6773: 6772: 6771: 6760: 6758: 6754: 6753: 6751: 6750: 6745: 6740: 6734: 6732: 6728: 6727: 6725: 6724: 6719: 6714: 6704: 6703: 6698: 6693: 6683: 6681: 6672: 6661: 6652: 6643: 6637: 6636: 6633: 6632: 6630: 6629: 6624: 6619: 6614: 6608: 6606: 6600: 6599: 6597: 6596: 6590: 6588: 6582: 6581: 6579: 6578: 6565: 6563: 6554: 6538: 6527: 6519: 6518: 6510:Chromalveolata 6502:Antiparasitics 6498: 6497: 6490: 6483: 6475: 6466: 6465: 6462: 6461: 6460: 6459: 6456: 6445: 6439: 6433: 6432: 6429: 6428: 6425: 6424: 6421: 6420: 6418: 6417: 6407: 6402: 6397: 6383: 6369: 6350: 6348: 6346:Streptogramins 6342: 6341: 6339: 6338: 6333: 6328: 6322: 6320: 6314: 6313: 6311: 6310: 6305: 6300: 6294: 6292: 6286: 6285: 6283: 6282: 6277: 6272: 6267: 6265:Troleandomycin 6262: 6257: 6252: 6247: 6242: 6237: 6232: 6227: 6222: 6217: 6212: 6207: 6202: 6197: 6195:Flurithromycin 6192: 6187: 6182: 6180:Clarithromycin 6177: 6172: 6167: 6162: 6156: 6154: 6145: 6137: 6136: 6133: 6132: 6130: 6129: 6124: 6119: 6114: 6108: 6106: 6097: 6091: 6090: 6088: 6087: 6082: 6077: 6072: 6067: 6062: 6057: 6051: 6049: 6034: 6028: 6027: 6024: 6023: 6020: 6019: 6017: 6016: 6010: 6008: 6006:Glycylcyclines 6002: 6001: 5999: 5998: 5993: 5988: 5983: 5978: 5973: 5968: 5963: 5958: 5953: 5948: 5943: 5941:Demeclocycline 5938: 5933: 5928: 5922: 5920: 5913: 5901: 5900: 5897: 5896: 5894: 5893: 5887: 5885: 5881: 5880: 5878: 5877: 5872: 5866: 5865: 5864: 5863: 5858: 5853: 5848: 5843: 5832: 5830: 5826:Micromonospora 5820: 5819: 5817: 5816: 5814:Nourseothricin 5811: 5806: 5801: 5796: 5791: 5780: 5779: 5778: 5777: 5772: 5767: 5762: 5751: 5750: 5749: 5748: 5743: 5738: 5727: 5726: 5721: 5715: 5713: 5700: 5685: 5679: 5678: 5650:Antibacterials 5646: 5645: 5638: 5631: 5623: 5614: 5613: 5611: 5610: 5605: 5598: 5593: 5588: 5583: 5578: 5573: 5568: 5562: 5560: 5556: 5555: 5552: 5551: 5549: 5548: 5543: 5537: 5535: 5531: 5530: 5528: 5527: 5525:Amphotericin B 5522: 5517: 5511: 5509: 5503: 5502: 5500: 5499: 5493: 5491: 5485: 5484: 5482: 5481: 5476: 5471: 5466: 5461: 5456: 5451: 5446: 5441: 5436: 5431: 5426: 5421: 5416: 5411: 5405: 5403: 5394: 5388: 5387: 5385: 5384: 5378: 5376: 5370: 5369: 5367: 5366: 5361: 5356: 5350: 5348: 5342: 5341: 5339: 5338: 5333: 5331:Broxyquinoline 5328: 5323: 5321:Chlorquinaldol 5318: 5313: 5307: 5305: 5298: 5297: 5295: 5294: 5288: 5286: 5279: 5278: 5276: 5275: 5270: 5265: 5260: 5255: 5250: 5245: 5240: 5234: 5232: 5226: 5225: 5206: 5205: 5198: 5191: 5183: 5174: 5173: 5170: 5169: 5168: 5167: 5164: 5153: 5147: 5141: 5140: 5137: 5136: 5134: 5133: 5128: 5123: 5118: 5113: 5108: 5103: 5098: 5092: 5090: 5086: 5085: 5083: 5082: 5077: 5072: 5067: 5062: 5056: 5054: 5050: 5049: 5047: 5046: 5041: 5036: 5031: 5026: 5021: 5015: 5013: 5007: 5006: 5004: 5003: 5002: 5001: 4996: 4986: 4985: 4984: 4981:Spironolactone 4978: 4973: 4968: 4963: 4952: 4950: 4944: 4943: 4941: 4940: 4934: 4929: 4920: 4915: 4910: 4905: 4899: 4897: 4891: 4890: 4888: 4887: 4882: 4877: 4872: 4866: 4864: 4858: 4857: 4855: 4854: 4849: 4844: 4842:Salicylic acid 4839: 4833: 4831: 4825: 4824: 4822: 4821: 4816: 4811: 4806: 4801: 4795: 4793: 4787: 4786: 4774: 4773: 4766: 4759: 4751: 4745: 4744: 4730: 4729:External links 4727: 4724: 4723: 4685: 4647: 4622: 4589: 4570:(7): 1117–33. 4553: 4546: 4526: 4477: 4428: 4377: 4318: 4308: 4265: 4253: 4199: 4172: 4137:Appl Microbiol 4123: 4088: 4055: 4014: 3973: 3948:Anesthesiology 3938: 3912: 3868: 3853: 3835: 3792: 3751: 3722:(8): 2315–20. 3702: 3667: 3618: 3566: 3544: 3501: 3470:(6): 1309–14. 3448: 3412: 3369: 3318: 3272: 3243:(5): 1249–56. 3221: 3186: 3143: 3116:(8): 1701–10. 3100: 3049: 3005: 2966:(8): 2315–20. 2937: 2918:(12): 1115–8. 2899: 2885:10.1086/324626 2858: 2855:. 1 June 2020. 2837: 2808:Capnocytophaga 2798: 2779: 2757: 2723: 2670: 2627: 2589: 2553: 2535:(9): 2123–30. 2515: 2474: 2445: 2410: 2385: 2355: 2321: 2314: 2293: 2265: 2254: 2235: 2184: 2163:(6): 1339–50. 2140: 2114: 2089: 2051: 2040: 2015: 1972: 1944: 1916: 1887: 1873: 1872: 1870: 1867: 1846: 1845:Veterinary use 1843: 1808:Sanofi-Aventis 1785:vaginal ovules 1760: 1757: 1748: 1745: 1743: 1740: 1678:bacteriostatic 1665: 1662: 1619:derivative of 1604: 1601: 1572: 1569: 1545: 1542: 1520: 1515: 1511:hepatotoxicity 1480:metallic taste 1447: 1444: 1359:agent such as 1327: 1324: 1291: 1288: 1245: 1225: 1205: 1202: 1201: 1200: 1194: 1188: 1134: 1133: 1099: 1074:Staphylococcus 1057: 1054: 1050:salicylic acid 1033: 1030: 980: 977: 873: 872: 855: 854: 852: 851: 848: 846: 843: 835: 834: 833: 830: 829: 827: 826: 823: 815: 814: 813: 810: 809: 807: 806: 798: 796: 788: 787: 781: 775: 774: 768: 762: 753: 747: 742: 736: 735: 731: 730: 720: 712: 711: 709: 708: 700:DTXSID90928608 695: 693: 680: 679: 677: 676: 660: 658: 652: 651: 649: 648: 640: 638: 632: 631: 629: 628: 620: 618: 612: 611: 609: 608: 600: 592: 590: 584: 583: 581: 580: 572: 570: 564: 563: 561: 560: 552: 550: 544: 543: 541: 540: 532: 530: 524: 523: 521: 520: 512: 510: 499: 498: 496: 495: 487: 485: 479: 478: 476: 475: 464: 456: 455: 454: 451: 450: 446: 445: 435: 429: 428: 425: 416: 415: 410: 404: 403: 400: 394: 393: 392:4–5% (topical) 390:90% (by mouth) 388: 382: 381: 374: 373: 371: 370: 355: 342: 331: 317: 315: 309: 308: 304: 303: 301: 300: 257: 255: 249: 248: 243: 237: 236: 219: 217:administration 211: 210: 208: 207: 205: 195: 193: 185: 184: 182: 181: 163: 161: 155: 154: 147: 141: 140: 133: 123: 122: 117: 113: 112: 109: 103: 102: 53: 49: 48: 44: 43: 35: 34: 15: 9: 6: 4: 3: 2: 8287: 8276: 8273: 8271: 8268: 8266: 8263: 8261: 8258: 8256: 8253: 8251: 8248: 8246: 8243: 8242: 8240: 8230: 8220: 8219: 8216: 8203: 8202: 8198: 8195: 8194: 8191: 8185: 8182: 8180: 8177: 8174: 8173: 8170: 8167: 8165: 8162: 8160: 8157: 8155: 8152: 8150: 8147: 8145: 8142: 8140: 8137: 8135: 8132: 8130: 8127: 8125: 8122: 8120: 8117: 8115: 8112: 8110: 8107: 8105: 8102: 8100: 8097: 8095: 8094:Sulfisoxazole 8092: 8090: 8087: 8085: 8082: 8080: 8077: 8075: 8072: 8070: 8067: 8065: 8062: 8060: 8057: 8055: 8052: 8050: 8047: 8045: 8042: 8040: 8037: 8035: 8032: 8030: 8027: 8025: 8022: 8020: 8017: 8015: 8012: 8010: 8007: 8005: 8002: 8000: 7997: 7995: 7992: 7990: 7987: 7985: 7982: 7980: 7977: 7975: 7972: 7970: 7969:Phenobarbital 7967: 7965: 7962: 7960: 7957: 7955: 7952: 7950: 7947: 7945: 7942: 7940: 7937: 7935: 7932: 7930: 7927: 7925: 7922: 7920: 7917: 7915: 7912: 7910: 7907: 7905: 7902: 7900: 7897: 7895: 7892: 7890: 7887: 7885: 7882: 7880: 7877: 7875: 7872: 7870: 7867: 7865: 7861: 7857: 7855: 7854:Levothyroxine 7852: 7850: 7847: 7845: 7842: 7840: 7838: 7834: 7832: 7829: 7827: 7824: 7822: 7819: 7817: 7816:Guggulsterone 7814: 7812: 7809: 7807: 7804: 7802: 7799: 7797: 7794: 7792: 7789: 7787: 7784: 7782: 7779: 7777: 7774: 7772: 7769: 7767: 7764: 7762: 7759: 7757: 7754: 7752: 7749: 7747: 7744: 7742: 7739: 7737: 7734: 7732: 7729: 7727: 7724: 7722: 7719: 7717: 7714: 7712: 7711:Dicloxacillin 7709: 7707: 7704: 7702: 7699: 7696: 7692: 7689: 7686: 7682: 7679: 7677: 7676:Dexamethasone 7674: 7672: 7669: 7667: 7664: 7662: 7659: 7657: 7654: 7652: 7649: 7647: 7644: 7642: 7639: 7637: 7634: 7632: 7629: 7627: 7624: 7622: 7619: 7617: 7614: 7612: 7611:Cephaloridine 7609: 7607: 7604: 7602: 7599: 7597: 7594: 7592: 7589: 7587: 7584: 7582: 7579: 7577: 7574: 7572: 7569: 7567: 7564: 7562: 7559: 7557: 7554: 7552: 7549: 7547: 7544: 7542: 7539: 7537: 7534: 7532: 7529: 7527: 7524: 7522: 7519: 7517: 7514: 7512: 7509: 7507: 7504: 7501: 7500: 7498: 7493: 7487: 7481: 7478: 7476: 7473: 7471: 7468: 7466: 7463: 7461: 7458: 7456: 7453: 7451: 7448: 7446: 7443: 7441: 7438: 7436: 7433: 7431: 7428: 7426: 7423: 7421: 7418: 7415: 7414: 7411: 7410:Valproic acid 7408: 7406: 7403: 7401: 7398: 7396: 7393: 7391: 7388: 7386: 7383: 7381: 7378: 7376: 7373: 7371: 7370:Phenobarbital 7368: 7366: 7363: 7361: 7358: 7356: 7353: 7351: 7348: 7346: 7343: 7341: 7338: 7336: 7333: 7331: 7328: 7326: 7323: 7321: 7318: 7315: 7311: 7308: 7306: 7303: 7301: 7298: 7296: 7293: 7291: 7288: 7286: 7283: 7281: 7278: 7276: 7273: 7271: 7270:Carbamazepine 7268: 7266: 7263: 7261: 7258: 7256: 7253: 7251: 7248: 7245: 7244: 7242: 7237: 7231: 7227: 7224: 7217: 7212: 7210: 7205: 7203: 7198: 7197: 7194: 7178: 7176: 7173: 7172: 7170: 7167: 7164: 7161: 7159: 7156: 7155: 7151: 7145: 7144:metronidazole 7141: 7138: 7137: 7135: 7133: 7127: 7117: 7113: 7112:Balantidiasis 7110: 7109: 7107: 7105: 7099: 7085: 7082: 7081: 7079: 7077: 7073: 7058: 7055: 7052: 7050:artesunate/SP 7049: 7046: 7045: 7043: 7037: 7031: 7028: 7026: 7023: 7020: 7017: 7014: 7011: 7008: 7005: 7003: 7000: 6999: 6997: 6995: 6990: 6987: 6981: 6971: 6968: 6966: 6963: 6961: 6958: 6956: 6953: 6951: 6948: 6946: 6943: 6940: 6936: 6933: 6932: 6930: 6926: 6920: 6917: 6915: 6912: 6910: 6907: 6905: 6902: 6900: 6897: 6896: 6894: 6892: 6889:Sesquiterpene 6886: 6875: 6872: 6871: 6869: 6865: 6859: 6856: 6854: 6851: 6850: 6848: 6846: 6842: 6834: 6831: 6829: 6826: 6825: 6824: 6823: 6819: 6818: 6815: 6812: 6810: 6809:pyrimethamine 6807: 6806: 6804: 6802: 6798: 6795: 6793: 6789: 6779: 6776: 6775: 6770: 6767: 6766: 6765: 6762: 6761: 6759: 6755: 6749: 6746: 6744: 6741: 6739: 6736: 6735: 6733: 6729: 6723: 6720: 6718: 6715: 6713: 6709: 6706: 6705: 6702: 6699: 6697: 6694: 6692: 6688: 6685: 6684: 6682: 6680: 6676: 6673: 6671: 6665: 6662: 6656: 6653: 6651: 6647: 6644: 6642: 6638: 6628: 6625: 6623: 6620: 6618: 6615: 6613: 6612:pyrimethamine 6610: 6609: 6607: 6605: 6604:Toxoplasmosis 6601: 6595: 6592: 6591: 6589: 6587: 6583: 6576: 6572: 6571: 6567: 6566: 6564: 6562: 6558: 6555: 6552: 6551:Coccidiostats 6546: 6542: 6539: 6537: 6531: 6528: 6526: 6520: 6515: 6511: 6507: 6503: 6496: 6491: 6489: 6484: 6482: 6477: 6476: 6473: 6457: 6455: 6452: 6451: 6449: 6446: 6443: 6440: 6438: 6435: 6434: 6430: 6415: 6411: 6410:Virginiamycin 6408: 6406: 6403: 6401: 6398: 6395: 6391: 6387: 6384: 6381: 6377: 6373: 6370: 6367: 6363: 6359: 6355: 6354:Pristinamycin 6352: 6351: 6349: 6347: 6343: 6337: 6334: 6332: 6329: 6327: 6324: 6323: 6321: 6319: 6315: 6309: 6308:Solithromycin 6306: 6304: 6301: 6299: 6298:Telithromycin 6296: 6295: 6293: 6291: 6287: 6281: 6278: 6276: 6273: 6271: 6270:Tulathromycin 6268: 6266: 6263: 6261: 6258: 6256: 6253: 6251: 6250:Telithromycin 6248: 6246: 6243: 6241: 6240:Solithromycin 6238: 6236: 6235:Roxithromycin 6233: 6231: 6228: 6226: 6223: 6221: 6218: 6216: 6213: 6211: 6208: 6206: 6203: 6201: 6200:Gamithromycin 6198: 6196: 6193: 6191: 6188: 6186: 6185:Dirithromycin 6183: 6181: 6178: 6176: 6173: 6171: 6168: 6166: 6163: 6161: 6158: 6157: 6155: 6153: 6149: 6146: 6143: 6138: 6128: 6125: 6123: 6122:Thiamphenicol 6120: 6118: 6117:Azidamfenicol 6115: 6113: 6110: 6109: 6107: 6105: 6101: 6098: 6096: 6092: 6086: 6083: 6081: 6078: 6076: 6073: 6071: 6068: 6066: 6063: 6061: 6058: 6056: 6053: 6052: 6050: 6047: 6042: 6041:Oxazolidinone 6038: 6035: 6033: 6029: 6015: 6012: 6011: 6009: 6007: 6003: 5997: 5994: 5992: 5989: 5987: 5984: 5982: 5979: 5977: 5974: 5972: 5969: 5967: 5964: 5962: 5959: 5957: 5954: 5952: 5949: 5947: 5944: 5942: 5939: 5937: 5934: 5932: 5929: 5927: 5924: 5923: 5921: 5919:Tetracyclines 5917: 5914: 5911: 5906: 5902: 5892: 5889: 5888: 5886: 5882: 5876: 5873: 5871: 5868: 5867: 5862: 5859: 5857: 5854: 5852: 5849: 5847: 5844: 5842: 5839: 5838: 5837: 5834: 5833: 5831: 5828: 5827: 5821: 5815: 5812: 5810: 5807: 5805: 5802: 5800: 5797: 5795: 5794:Spectinomycin 5792: 5789: 5785: 5782: 5781: 5776: 5773: 5771: 5768: 5766: 5763: 5761: 5758: 5757: 5756: 5753: 5752: 5747: 5744: 5742: 5739: 5737: 5734: 5733: 5732: 5729: 5728: 5725: 5722: 5720: 5717: 5716: 5714: 5711: 5710: 5704: 5701: 5698: 5693: 5689: 5686: 5684: 5680: 5675: 5671: 5667: 5663: 5659: 5655: 5651: 5644: 5639: 5637: 5632: 5630: 5625: 5624: 5621: 5609: 5608:Copper usnate 5606: 5604: 5603: 5599: 5597: 5594: 5592: 5589: 5587: 5584: 5582: 5579: 5577: 5574: 5572: 5569: 5567: 5564: 5563: 5561: 5557: 5547: 5544: 5542: 5539: 5538: 5536: 5532: 5526: 5523: 5521: 5518: 5516: 5513: 5512: 5510: 5508: 5504: 5498: 5495: 5494: 5492: 5490: 5486: 5480: 5477: 5475: 5472: 5470: 5467: 5465: 5462: 5460: 5459:Propenidazole 5457: 5455: 5452: 5450: 5449:Fenticonazole 5447: 5445: 5442: 5440: 5437: 5435: 5432: 5430: 5427: 5425: 5422: 5420: 5417: 5415: 5412: 5410: 5409:Metronidazole 5407: 5406: 5404: 5402: 5398: 5395: 5393: 5389: 5383: 5382:Sulfatolamide 5380: 5379: 5377: 5375: 5371: 5365: 5364:Ascorbic acid 5362: 5360: 5357: 5355: 5352: 5351: 5349: 5347: 5346:Organic acids 5343: 5337: 5334: 5332: 5329: 5327: 5324: 5322: 5319: 5317: 5314: 5312: 5309: 5308: 5306: 5303: 5299: 5293: 5290: 5289: 5287: 5284: 5280: 5274: 5271: 5269: 5266: 5264: 5261: 5259: 5256: 5254: 5251: 5249: 5246: 5244: 5241: 5239: 5236: 5235: 5233: 5231: 5227: 5222: 5218: 5214: 5211: 5210:Gynecological 5204: 5199: 5197: 5192: 5190: 5185: 5184: 5181: 5165: 5163: 5160: 5159: 5157: 5154: 5151: 5148: 5146: 5143: 5142: 5138: 5132: 5129: 5127: 5124: 5122: 5119: 5117: 5114: 5112: 5109: 5107: 5104: 5102: 5099: 5097: 5094: 5093: 5091: 5087: 5081: 5078: 5076: 5073: 5071: 5068: 5066: 5063: 5061: 5058: 5057: 5055: 5051: 5045: 5042: 5040: 5037: 5035: 5032: 5030: 5027: 5025: 5022: 5020: 5017: 5016: 5014: 5012: 5008: 5000: 4997: 4995: 4992: 4991: 4990: 4987: 4982: 4979: 4977: 4974: 4972: 4969: 4967: 4964: 4962: 4959: 4958: 4957: 4956:Antiandrogens 4954: 4953: 4951: 4949: 4945: 4938: 4935: 4933: 4930: 4928: 4924: 4923:Tetracyclines 4921: 4919: 4918:Sulfacetamide 4916: 4914: 4911: 4909: 4906: 4904: 4901: 4900: 4898: 4896: 4892: 4886: 4883: 4881: 4878: 4876: 4873: 4871: 4868: 4867: 4865: 4863: 4859: 4853: 4850: 4848: 4845: 4843: 4840: 4838: 4837:Glycolic acid 4835: 4834: 4832: 4830: 4826: 4820: 4817: 4815: 4812: 4810: 4807: 4805: 4802: 4800: 4797: 4796: 4794: 4792: 4791:Antibacterial 4788: 4783: 4779: 4772: 4767: 4765: 4760: 4758: 4753: 4752: 4749: 4743: 4739: 4738: 4733: 4732: 4720: 4719:0-911910-50-6 4716: 4712: 4708: 4707: 4702: 4698: 4695: 4689: 4682: 4681:0-911910-50-6 4678: 4674: 4670: 4669: 4664: 4660: 4657: 4651: 4636: 4632: 4626: 4610: 4606: 4605: 4600: 4593: 4585: 4581: 4577: 4573: 4569: 4565: 4557: 4549: 4543: 4539: 4538: 4530: 4522: 4518: 4513: 4508: 4504: 4500: 4496: 4492: 4488: 4481: 4473: 4469: 4465: 4461: 4456: 4451: 4448:(2): 257–70. 4447: 4443: 4439: 4432: 4424: 4420: 4416: 4412: 4408: 4404: 4400: 4396: 4392: 4388: 4381: 4373: 4369: 4364: 4359: 4354: 4349: 4345: 4341: 4337: 4333: 4329: 4322: 4312: 4304: 4300: 4296: 4292: 4288: 4284: 4280: 4276: 4269: 4262: 4257: 4249: 4245: 4241: 4237: 4233: 4229: 4226:(4): 455–64. 4225: 4221: 4214: 4212: 4210: 4208: 4206: 4204: 4195: 4191: 4187: 4183: 4176: 4168: 4164: 4159: 4154: 4150: 4146: 4142: 4138: 4134: 4127: 4119: 4115: 4111: 4107: 4104:(4): 616–19. 4103: 4099: 4092: 4076: 4072: 4068: 4062: 4060: 4051: 4047: 4042: 4037: 4033: 4029: 4025: 4018: 4010: 4006: 4001: 3996: 3992: 3988: 3987:Can J Anaesth 3984: 3977: 3969: 3965: 3961: 3957: 3953: 3949: 3942: 3934: 3930: 3926: 3922: 3921:"Clindamycin" 3916: 3908: 3904: 3900: 3896: 3892: 3888: 3885:(9): 1103–9. 3884: 3880: 3872: 3864: 3860: 3856: 3854:9780826128584 3850: 3846: 3839: 3831: 3819: 3811: 3807: 3803: 3796: 3788: 3784: 3779: 3774: 3771:(3): 776–89. 3770: 3766: 3762: 3755: 3747: 3743: 3738: 3733: 3729: 3725: 3721: 3717: 3713: 3706: 3698: 3694: 3690: 3686: 3683:(4): 257–62. 3682: 3678: 3671: 3663: 3659: 3654: 3649: 3645: 3641: 3637: 3633: 3629: 3622: 3614: 3610: 3605: 3600: 3596: 3592: 3588: 3584: 3580: 3573: 3571: 3562: 3561: 3553: 3551: 3549: 3540: 3536: 3532: 3528: 3524: 3520: 3516: 3512: 3505: 3497: 3493: 3488: 3483: 3478: 3473: 3469: 3465: 3464: 3459: 3452: 3444: 3440: 3436: 3432: 3429:(6): 418–22. 3428: 3425:(in French). 3424: 3416: 3408: 3404: 3400: 3396: 3392: 3388: 3385:(7): 603–16. 3384: 3381:(in German). 3380: 3379:Ophthalmologe 3373: 3365: 3361: 3356: 3351: 3346: 3341: 3338:(3): 451–69. 3337: 3333: 3329: 3322: 3314: 3310: 3306: 3302: 3298: 3294: 3290: 3286: 3279: 3277: 3268: 3264: 3259: 3254: 3250: 3246: 3242: 3238: 3237: 3236:J Clin Invest 3232: 3225: 3217: 3213: 3209: 3205: 3202:(6): 587–97. 3201: 3197: 3190: 3182: 3178: 3174: 3170: 3166: 3162: 3159:(5): 638–42. 3158: 3154: 3147: 3139: 3135: 3131: 3127: 3123: 3119: 3115: 3111: 3104: 3096: 3092: 3087: 3082: 3078: 3074: 3070: 3066: 3065: 3060: 3053: 3045: 3041: 3036: 3031: 3027: 3023: 3019: 3012: 3010: 3001: 2997: 2992: 2987: 2983: 2979: 2974: 2969: 2965: 2961: 2960: 2955: 2948: 2946: 2944: 2942: 2933: 2929: 2925: 2921: 2917: 2913: 2906: 2904: 2895: 2891: 2886: 2881: 2878:(4): 482–92. 2877: 2873: 2869: 2862: 2854: 2847: 2841: 2833: 2829: 2825: 2821: 2818:(4): 367–73. 2817: 2813: 2810:infections". 2809: 2802: 2795: 2786: 2782: 2776: 2772: 2768: 2761: 2745: 2741: 2737: 2730: 2728: 2719: 2715: 2711: 2707: 2702: 2701:11368/3020691 2697: 2693: 2689: 2685: 2681: 2674: 2658: 2654: 2650: 2649: 2644: 2638: 2636: 2634: 2632: 2623: 2619: 2615: 2611: 2607: 2603: 2596: 2594: 2585: 2581: 2578:(8): 475–84. 2577: 2573: 2569: 2562: 2560: 2558: 2546: 2542: 2538: 2534: 2530: 2526: 2519: 2511: 2507: 2502: 2497: 2494:(6): 928–35. 2493: 2489: 2485: 2478: 2462: 2458: 2452: 2450: 2441: 2437: 2433: 2429: 2425: 2421: 2414: 2399: 2395: 2389: 2373: 2369: 2365: 2359: 2343: 2339: 2337: 2331: 2325: 2317: 2315:9781284057560 2311: 2307: 2300: 2298: 2288: 2283: 2279: 2275: 2269: 2261: 2257: 2255:9781118819517 2251: 2247: 2246: 2239: 2231: 2227: 2222: 2217: 2212: 2207: 2203: 2199: 2195: 2188: 2180: 2176: 2171: 2166: 2162: 2158: 2154: 2147: 2145: 2128: 2124: 2118: 2103: 2099: 2093: 2085: 2081: 2077: 2073: 2070:(4): 380–90. 2069: 2065: 2058: 2056: 2047: 2043: 2041:9783540331018 2037: 2033: 2032: 2024: 2022: 2020: 2003: 1999: 1993: 1991: 1989: 1987: 1985: 1983: 1981: 1979: 1977: 1961: 1957: 1951: 1949: 1933:. 6 June 2024 1932: 1931: 1930:Health Canada 1926: 1920: 1905: 1901: 1897: 1891: 1884: 1878: 1874: 1866: 1864: 1860: 1859:toxoplasmosis 1856: 1855:osteomyelitis 1852: 1842: 1840: 1835: 1833: 1829: 1825: 1821: 1818:form made by 1817: 1813: 1809: 1805: 1800: 1798: 1794: 1790: 1786: 1782: 1778: 1777:hydrochloride 1774: 1765: 1756: 1754: 1739: 1737: 1736: 1731: 1727: 1726: 1721: 1720: 1715: 1714: 1708: 1706: 1702: 1701:pleuromutilin 1698: 1697:oxazolidinone 1694: 1691: 1687: 1683: 1679: 1670: 1661: 1659: 1654: 1651: 1647: 1643: 1639: 1635: 1631: 1630: 1626: 1622: 1618: 1617:semisynthetic 1609: 1600: 1598: 1594: 1590: 1586: 1582: 1578: 1568: 1566: 1562: 1558: 1554: 1549: 1541: 1539: 1535: 1531: 1530: 1525: 1519: 1514: 1512: 1508: 1504: 1500: 1499:polyarthritis 1496: 1492: 1487: 1485: 1481: 1477: 1473: 1469: 1465: 1461: 1457: 1453: 1443: 1441: 1436: 1434: 1432: 1427: 1423: 1422:toxoplasmosis 1418: 1416: 1411: 1409: 1405: 1400: 1398: 1394: 1390: 1389:immune system 1386: 1382: 1381: 1376: 1375: 1370: 1366: 1362: 1358: 1354: 1349: 1347: 1342: 1340: 1339: 1333: 1323: 1321: 1317: 1316: 1311: 1307: 1306: 1301: 1297: 1287: 1284: 1282: 1278: 1274: 1270: 1265: 1263: 1259: 1255: 1251: 1243: 1239: 1235: 1231: 1224:known as iMLS 1223: 1219: 1210: 1198: 1195: 1192: 1189: 1186: 1183: 1182: 1181: 1179: 1174: 1172: 1171: 1166: 1163: 1159: 1158: 1153: 1152: 1147: 1146: 1141: 1140: 1131: 1130: 1125: 1124: 1119: 1118: 1117:Fusobacterium 1113: 1112: 1107: 1104: 1103:Gram-negative 1100: 1097: 1093: 1089: 1086: 1082: 1081: 1080:Streptococcus 1076: 1075: 1070: 1067: 1066:Gram-positive 1063: 1062: 1061: 1053: 1051: 1047: 1038: 1029: 1027: 1023: 1022: 1017: 1013: 1009: 1005: 1001: 997: 993: 990: 986: 976: 970: 966: 962: 957: 955: 951: 949: 943: 941: 937: 933: 929: 928: 922: 918: 914: 910: 906: 902: 898: 894: 893:osteomyelitis 890: 886: 883: 879: 869: 862: 856: 847: 842: 841: 838: 831: 822: 821: 818: 811: 804: 800: 799: 797: 794: 789: 782: 780: 776: 743: 741: 737: 732: 728: 724: 721: 719: 717:ECHA InfoCard 713: 705: 701: 697: 696: 694: 685: 681: 673: 672:RCSB PDB 667: 662: 661: 659: 657: 653: 646: 642: 641: 639: 637: 633: 626: 622: 621: 619: 617: 613: 606: 602:as HCl:  601: 598: 594: 593: 591: 589: 585: 578: 574: 573: 571: 569: 565: 558: 554: 553: 551: 549: 545: 538: 534: 533: 531: 529: 525: 518: 514: 513: 511: 504: 500: 493: 489: 488: 486: 484: 480: 463: 462: 459: 452: 447: 443: 439: 436: 434: 430: 426: 424: 417: 414: 411: 409: 405: 401: 399: 395: 389: 387: 383: 379: 375: 368: 356: 353: 343: 341: 332: 329: 319: 318: 316: 314: 310: 305: 297: 292: 287: 282: 277: 272: 267: 262: 259: 258: 256: 254: 250: 247: 244: 242: 238: 235: 231: 227: 223: 220: 218: 212: 206: 197: 196: 194: 192: 186: 179: 174: 165: 164: 162: 160: 156: 152: 148: 146: 142: 138: 134: 132: 128: 124: 118: 114: 110: 108: 104: 98: 54: 52:Pronunciation 50: 47:Clinical data 45: 41: 36: 32: 27: 19: 8255:Lincosamides 8250:Carboxamides 8199: 8179:Ketoconazole 8176:Antagonists: 8175: 8149:Troglitazone 8124:Tetracycline 8079:Spiroxatrine 8024:Quingestrone 8019:Progesterone 8004:Pregnenolone 7999:Pregnanolone 7989:Pregnanediol 7984:Prednisolone 7909:Mifepristone 7836: 7811:Griseofulvin 7791:Fenbendazole 7776:Famprofazone 7771:Erythromycin 7766:Epothilone B 7751:Eburnamonine 7646:Clotrimazole 7636:Clofenvinfos 7630: 7571:Antimycotics 7502: 7465:Okadaic acid 7417:Antagonists: 7416: 7405:Troglitazone 7340:Mifepristone 7335:Methoxychlor 7330:Griseofulvin 7325:Ellagic acid 7305:Cypermethrin 7295:Clotrimazole 7246: 7116:tetracycline 7083: 7009:/piperaquine 6965:pyronaridine 6954: 6945:tetracycline 6845:Sulfonamides 6820: 6778:halofantrine 6769:+ artemether 6764:lumefantrine 6641:Aconoidasida 6621: 6617:sulfadiazine 6586:Isosporiasis 6575:nitazoxanide 6568: 6394:Quinupristin 6390:Dalfopristin 6325: 6318:Lincosamides 6255:Tildipirosin 6225:Oleandomycin 6190:Erythromycin 6160:Azithromycin 5996:Tetracycline 5971:Omadacycline 5956:Meclocycline 5946:Eravacycline 5936:Clomocycline 5851:Micronomicin 5824: 5799:Hygromycin B 5788:+loteprednol 5746:Ribostamycin 5719:Streptomycin 5709:Streptomyces 5707: 5600: 5586:Furazolidone 5576:Policresulen 5479:Flutrimazole 5464:Butoconazole 5444:Ketoconazole 5414:Clotrimazole 5374:Sulfonamides 5336:Oxyquinoline 5267: 5089:Combinations 5024:Isotretinoin 4971:Drospirenone 4961:Bicalutamide 4913:Erythromycin 4902: 4819:Tea tree oil 4799:Azelaic acid 4735: 4704: 4688: 4666: 4650: 4638:. Retrieved 4634: 4625: 4613:. Retrieved 4602: 4592: 4567: 4563: 4556: 4536: 4529: 4494: 4490: 4480: 4445: 4441: 4431: 4390: 4386: 4380: 4335: 4331: 4321: 4311: 4281:(1): 35–48. 4278: 4274: 4268: 4256: 4223: 4219: 4185: 4181: 4175: 4143:(5): 653–7. 4140: 4136: 4126: 4101: 4097: 4091: 4079:. Retrieved 4070: 4031: 4028:Anesth Analg 4027: 4017: 3993:(7): 614–7. 3990: 3986: 3976: 3954:(4): 407–8. 3951: 3947: 3941: 3924: 3915: 3882: 3878: 3871: 3844: 3838: 3801: 3795: 3768: 3764: 3754: 3719: 3715: 3705: 3680: 3676: 3670: 3635: 3631: 3621: 3589:(4): 542–5. 3586: 3582: 3558: 3514: 3510: 3504: 3467: 3461: 3451: 3426: 3422: 3415: 3382: 3378: 3372: 3335: 3331: 3328:"Babesiosis" 3321: 3288: 3284: 3240: 3234: 3224: 3199: 3195: 3189: 3156: 3152: 3146: 3113: 3109: 3103: 3068: 3062: 3052: 3025: 3021: 2963: 2957: 2915: 2911: 2875: 2871: 2861: 2852: 2840: 2815: 2811: 2807: 2801: 2785:the original 2770: 2760: 2748:. Retrieved 2744:the original 2739: 2683: 2679: 2673: 2661:. Retrieved 2646: 2608:(1): 52–62. 2605: 2601: 2575: 2571: 2532: 2528: 2518: 2491: 2487: 2477: 2465:. Retrieved 2461:the original 2426:(5): 550–8. 2423: 2419: 2413: 2401:. Retrieved 2397: 2388: 2376:. Retrieved 2367: 2358: 2346:. Retrieved 2333: 2324: 2305: 2287:10665/345533 2277: 2268: 2244: 2238: 2201: 2197: 2187: 2160: 2156: 2131:. Retrieved 2126: 2117: 2105:. Retrieved 2101: 2092: 2067: 2063: 2030: 2006:. Retrieved 1963:. Retrieved 1959: 1935:. Retrieved 1928: 1919: 1907:. Retrieved 1899: 1890: 1877: 1848: 1839:generic drug 1836: 1832:clotrimazole 1801: 1770: 1750: 1733: 1723: 1717: 1711: 1709: 1675: 1655: 1645: 1642:substitution 1633: 1627: 1614: 1574: 1571:Interactions 1565:hematochezia 1560: 1550: 1547: 1527: 1522: 1517: 1488: 1449: 1446:Side effects 1437: 1430: 1419: 1412: 1401: 1397:phagocytosis 1393:opsonization 1378: 1372: 1357:bactericidal 1350: 1343: 1337: 1329: 1319: 1313: 1303: 1293: 1285: 1276: 1273:erythromycin 1266: 1261: 1253: 1249: 1242:erythromycin 1215: 1196: 1190: 1184: 1175: 1168: 1155: 1149: 1143: 1137: 1135: 1127: 1121: 1115: 1109: 1088:pneumococcus 1084: 1078: 1072: 1059: 1043: 1019: 998:, skin, and 982: 979:Medical uses 958: 947: 944: 926: 917:endocarditis 905:strep throat 891:, including 877: 876: 865:   859:   444:(around 20%) 420:Elimination 313:Legal status 307:Legal status 234:intravaginal 159:License data 18: 8164:Zafirlukast 8134:Thiothixene 8114:Terconazole 8064:Simvastatin 7939:Nisoldipine 7934:Nilvadipine 7919:Nicardipine 7889:Metacycline 7716:Dimercaprol 7671:Demecolcine 7631:Clindamycin 7626:Ciglitazone 7576:Artemisinin 7556:Ambrisentan 7460:Nigramide J 7395:Telmisartan 7355:Nicardipine 7265:Benfuracarb 7260:Artemisinin 7165:from market 7084:clindamycin 6970:piperaquine 6955:clindamycin 6950:doxycycline 6939:+ proguanil 6904:artemisinin 6853:sulfadoxine 6814:cycloguanil 6792:Antifolates 6722:tafenoquine 6696:chloroquine 6691:amodiaquine 6658:Individual 6622:clindamycin 6570:thiazolides 6545:Conoidasida 6444:from market 6380:Linopristin 6326:Clindamycin 6303:Cethromycin 6230:Rokitamycin 6215:Midecamycin 6210:Kitasamycin 6127:Florfenicol 6104:Amphenicols 6048:inhibitors) 6014:Tigecycline 5991:Sarecycline 5966:Minocycline 5961:Metacycline 5951:Lymecycline 5926:Doxycycline 5770:Bekanamycin 5741:Paromomycin 5699:inhibitors) 5497:Terconazole 5474:Oxiconazole 5469:Omoconazole 5454:Azanidazole 5439:Tioconazole 5434:Isoconazole 5392:Antifungals 5359:Acetic acid 5354:Lactic acid 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