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Classical genetics

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197:. The process by which characteristics are passed down from parents to their offspring is called heredity. In the sense of classical genetics, variation is known as the lack of resemblance in related individuals and can be categorized as discontinuous or continuous. Genes are a fundamental part of DNA that is aligned linearly on a eukaryotic chromosome. Chemical information that is transported and encoded by each gene is referred to as a trait. Many organisms possess two genes for each individual trait that is present within that particular individual. These paired genes that control the same trait is classified as an allele. In an individual, the allelic genes that are expressed can be either homozygous, meaning the same, or heterozygous, meaning different. Many pairs of alleles have differing effects that are portrayed in an offspring's 268:
him to see which of these two traits was dominant and which was recessive based upon the number of offspring with each phenotype. Mendel then chose to further his experiments by crossing a pea plant homozygous dominant for round and yellow phenotypes with a pea plant that was homozygous recessive for wrinkled and green. The plants that were originally crossed are known as the parental generation, or P generation, and the offspring resulting from the parental cross is known as the first filial, or F1, generation. The plants of the F1 generation resulting from this hybrid cross were all heterozygous round and yellow seeds.
25: 1168: 205:. The phenotype is a general term that defines an individual's visible, physical traits. The genotype of an offspring is known as its genetic makeup. The alleles of genes can either be dominant or recessive. A dominant allele needs only one copy to be expressed while a recessive allele needs two copies (homozygous) in a diploid organism to be expressed. Dominant and recessive alleles help to determine the offspring's genotypes, and therefore phenotypes. 221:. Mendelian inheritance is the process in which genes and traits are passed from a set of parents to their offspring. These inherited traits are passed down mechanistically with one gene from one parent and the second gene from another parent in sexually reproducing organisms. This creates the pair of genes in diploid organisms. Gregor Mendel started his experimentation and study of 267:
Mendel took peas that had differing phenotypic characteristics and test-crossed them to assess how the parental plants passed the traits down to their offspring. He started by crossing a round, yellow and round, green pea and observed the resulting phenotypes. The results of this experiment allowed
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In other words, we can say that classical genetics is basis of the modern genetics. Classical genetics is the Mendelian genetics or the older concepts of the genetics, which solely expressed based on the phenotypes resulted from breeding experiments while the modern genetics is the new concept of
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Classical genetics is a hallmark of the start of great discovery in biology, and has led to increased understanding of multiple important components of molecular genetics, human genetics, medical genetics, and much more. Thus, reinforcing Mendel's nickname as the father of modern genetics.
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two peas of different colors and observing the resulting phenotypes. After determining how the traits were likely inherited, he began to expand the amount of traits observed and tested and eventually expanded his experimentation by increasing the number of different organisms he tested.
142:, the avenues of investigation open to geneticists were greatly broadened. Some classical genetic ideas have been supplanted with the mechanistic understanding brought by molecular discoveries, but many remain intact and in use. Classical genetics is often contrasted with 240:
peas. Seven different phenotypic characteristics were studied and tested in the peas, including seed color, flower color and seed shape. The seven different characteristics which Mendel selected / checked for the experiment were as follows:
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with phenotypes of garden peas and continued the experiments with plants. He focused on the patterns of the traits that were being passed down from one generation to the next generation. This was assessed by
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who made it possible to identify the basic mechanisms of heredity. Subsequently, these mechanisms have been studied and explained at the molecular level.
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based solely on visible results of reproductive acts. It is the oldest discipline in the field of genetics, going back to the experiments on
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Smýkal, Petr; Varshney, Rajeev K.; Singh, Vikas K.; Coyne, Clarice J.; Domoney, Claire; Kejnovský, Eduard; Warkentin, Thomas (2016-12-01).
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concerned solely with the transmission of genetic traits via reproductive acts. Genetics is, generally, the study of genes,
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broke the laws of Mendelian inheritance and provided science with a way to map characteristics to a location on the
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Classical genetics consists of the techniques and methodologies of genetics that were in use before the advent of
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About 150 years ago, Gregor Mendel published his first experiments with the test crossing of
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genetics, which allows the direct investigation of genotypes together with phenotypes.
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Classical genetics is often referred to as the oldest form of genetics, and began with
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experiments that formulated and defined a fundamental biological concept known as
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The set of genes for one or more characters possessed by an individual is the
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Height of the plant was checked, as if it is tall or dwarf.
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At the base of classical genetics is the concept of a
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Lagassé, Paul; University, Columbia (January 2000).
526: 524: 245:He checked the different shape of the ripen seeds 1184: 469:, in Vonk, Jennifer; Shackelford, Todd (eds.), 627:Van Dijk, Peter J.; Ellis, T. H. Noel (2016). 814: 626: 471:Encyclopedia of Animal Cognition and Behavior 248:The color of the seed's albumen was checked 103:. A key discovery of classical genetics in 821: 807: 720:: CS1 maint: location missing publisher ( 549:"Mendelian Genetics - Genetics Generation" 652: 609: 505: 446:. Englewood Cliffs, N.J.: Prentice-Hall. 69:Learn how and when to remove this message 260:Flower position on the axial was checked 32:This article includes a list of general 1154:List of genetics research organizations 687: 629:"The Full Breadth of Mendel's Genetics" 257:Color of the unripened pods was checked 1185: 464: 439: 177:for the determination of a character. 802: 690:Genetics : from genes to genomes 185:Classical genetics is the aspect of 153: 18: 13: 565: 115:do not segregate independently at 38:it lacks sufficient corresponding 14: 1204: 1167: 1166: 756:Theoretical and Applied Genetics 688:Leland., Hartwell (2014-09-05). 508:Classical and Molecular Genetics 479:10.1007/978-3-319-47829-6_2054-1 254:Shape of the ripen pods was seen 251:He then selected seed coat color 23: 506:Mohan Mia, Md (6 April 2016). 458: 433: 1: 596:(5431): 368–374. 1965-02-06. 586:"Centenary of Mendel's Paper" 533:. Columbia University Press. 440:Peters, James Arthur (1959). 426: 1113:Missing heritability problem 828: 111:. The observation that some 7: 645:10.1534/genetics.116.196626 510:. American Academic Press. 399: 180: 130:After the discovery of the 10: 1209: 443:Classic papers in genetics 208: 1162: 1141: 1040: 991: 935: 874: 836: 768:10.1007/s00122-016-2803-2 329: 324: 316:Dihybrid Cross (9:3:3:1) 292: 287: 173:individual often has two 279:Monohybrid Cross (3:1) 590:British Medical Journal 53:more precise citations. 465:Gautam, Akash (2018), 452:10.5962/bhl.title.6458 1149:List of genetic codes 671:"Mendel and his peas" 219:Mendelian inheritance 90:Mendelian inheritance 1048:Behavioural genetics 406:Dominance (genetics) 1128:Population genomics 1118:Molecular evolution 1078:Genetic engineering 553:Genetics Generation 140:restriction enzymes 1193:Classical genetics 1088:Genetic monitoring 421:Thomas Hunt Morgan 148:molecular genetics 134:and such tools of 82:Classical genetics 16:Branch of genetics 1180: 1179: 1103:He Jiankui affair 1093:Genetic genealogy 1083:Genetic diversity 1012:the British Isles 917:Genetic variation 762:(12): 2267–2280. 572:www.mendelweb.org 488:978-3-319-47829-6 397: 396: 314: 313: 191:genetic variation 154:Basic definitions 125:plant improvement 101:molecular biology 84:is the branch of 79: 78: 71: 1200: 1170: 1169: 1133:Reverse genetics 1108:Medical genetics 823: 816: 809: 800: 799: 795: 753: 743: 741: 740: 725: 719: 711: 684: 682: 681: 666: 656: 639:(4): 1327–1336. 623: 613: 581: 579: 578: 566:Mendel, Gregor. 562: 560: 559: 544: 532: 521: 498: 497: 496: 495: 462: 456: 455: 437: 319: 318: 282: 281: 144:reverse genetics 74: 67: 63: 60: 54: 49:this article by 40:inline citations 27: 26: 19: 1208: 1207: 1203: 1202: 1201: 1199: 1198: 1197: 1183: 1182: 1181: 1176: 1158: 1137: 1036: 1027:the Middle East 993:Archaeogenetics 987: 931: 870: 832: 827: 751: 738: 736: 728: 713: 712: 700: 679: 677: 669: 584: 576: 574: 557: 555: 547: 541: 518: 502: 501: 493: 491: 489: 467:"Mendel's Laws" 463: 459: 438: 434: 429: 402: 215:Gregor Mendel's 211: 183: 156: 109:genetic linkage 75: 64: 58: 55: 45:Please help to 44: 28: 24: 17: 12: 11: 5: 1206: 1196: 1195: 1178: 1177: 1175: 1174: 1163: 1160: 1159: 1157: 1156: 1151: 1145: 1143: 1139: 1138: 1136: 1135: 1130: 1125: 1123:Plant genetics 1120: 1115: 1110: 1105: 1100: 1095: 1090: 1085: 1080: 1075: 1070: 1065: 1063:Genome editing 1060: 1055: 1050: 1044: 1042: 1041:Related topics 1038: 1037: 1035: 1034: 1029: 1024: 1019: 1014: 1009: 1004: 998: 996: 989: 988: 986: 985: 980: 975: 970: 965: 963:Immunogenetics 960: 955: 950: 945: 939: 937: 933: 932: 930: 929: 924: 919: 914: 909: 904: 899: 894: 889: 884: 878: 876: 875:Key components 872: 871: 869: 868: 863: 858: 853: 848: 843: 837: 834: 833: 826: 825: 818: 811: 803: 797: 796: 744: 734:www.nature.com 726: 699:978-0073525310 698: 685: 667: 624: 582: 563: 545: 539: 522: 516: 500: 499: 487: 457: 431: 430: 428: 425: 424: 423: 418: 413: 408: 401: 398: 395: 394: 391: 388: 385: 381: 380: 377: 374: 371: 367: 366: 363: 360: 357: 353: 352: 349: 346: 343: 340: 327: 326: 323: 312: 311: 308: 304: 303: 300: 297: 290: 289: 286: 265: 264: 261: 258: 255: 252: 249: 246: 210: 207: 182: 179: 155: 152: 77: 76: 31: 29: 22: 15: 9: 6: 4: 3: 2: 1205: 1194: 1191: 1190: 1188: 1173: 1165: 1164: 1161: 1155: 1152: 1150: 1147: 1146: 1144: 1140: 1134: 1131: 1129: 1126: 1124: 1121: 1119: 1116: 1114: 1111: 1109: 1106: 1104: 1101: 1099: 1096: 1094: 1091: 1089: 1086: 1084: 1081: 1079: 1076: 1074: 1071: 1069: 1066: 1064: 1061: 1059: 1056: 1054: 1051: 1049: 1046: 1045: 1043: 1039: 1033: 1030: 1028: 1025: 1023: 1020: 1018: 1015: 1013: 1010: 1008: 1005: 1003: 1000: 999: 997: 994: 990: 984: 981: 979: 976: 974: 971: 969: 966: 964: 961: 959: 956: 954: 951: 949: 946: 944: 941: 940: 938: 934: 928: 925: 923: 920: 918: 915: 913: 910: 908: 905: 903: 900: 898: 895: 893: 890: 888: 885: 883: 880: 879: 877: 873: 867: 864: 862: 859: 857: 854: 852: 849: 847: 844: 842: 839: 838: 835: 831: 824: 819: 817: 812: 810: 805: 804: 801: 793: 789: 785: 781: 777: 773: 769: 765: 761: 757: 750: 745: 735: 731: 727: 723: 717: 709: 705: 701: 695: 691: 686: 676: 672: 668: 664: 660: 655: 650: 646: 642: 638: 634: 630: 625: 621: 617: 612: 607: 603: 599: 595: 591: 587: 583: 573: 569: 564: 554: 550: 546: 542: 540:9780787650155 536: 531: 530: 523: 519: 517:9781631817762 513: 509: 504: 503: 490: 484: 480: 476: 472: 468: 461: 453: 449: 445: 444: 436: 432: 422: 419: 417: 414: 412: 409: 407: 404: 403: 392: 389: 386: 383: 382: 378: 375: 372: 369: 368: 364: 361: 358: 355: 354: 350: 347: 344: 341: 339: 336: 333: 328: 321: 320: 317: 309: 306: 305: 301: 298: 296: 291: 284: 283: 280: 277: 273: 269: 262: 259: 256: 253: 250: 247: 244: 243: 242: 239: 238: 232: 229: 228:test-crossing 224: 220: 216: 206: 204: 200: 196: 192: 188: 178: 176: 172: 168: 163: 161: 151: 149: 145: 141: 137: 133: 128: 126: 122: 118: 114: 110: 106: 102: 97: 95: 94:Gregor Mendel 91: 87: 83: 73: 70: 62: 59:December 2022 52: 48: 42: 41: 35: 30: 21: 20: 1073:Genetic code 1007:the Americas 983:Quantitative 953:Cytogenetics 948:Conservation 942: 841:Introduction 759: 755: 737:. 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Retrieved 552: 528: 507: 492:, retrieved 470: 460: 442: 435: 337: 334: 331: 315: 294: 278: 274: 270: 266: 235: 233: 212: 184: 164: 157: 132:genetic code 129: 98: 81: 80: 65: 56: 37: 1053:Epigenetics 223:inheritance 121:chromosomes 51:introducing 1058:Geneticist 1032:South Asia 978:Population 958:Ecological 927:Amino acid 907:Nucleotide 882:Chromosome 739:2017-11-29 680:2017-11-29 577:2017-11-29 558:2017-11-29 494:2022-10-09 427:References 105:eukaryotes 34:references 973:Molecular 968:Microbial 943:Classical 776:0040-5752 716:cite book 708:854285781 602:0007-1447 416:Phenotype 199:phenotype 1187:Category 1172:Category 1098:Heredity 1068:Genomics 912:Mutation 902:Heredity 866:Glossary 856:Timeline 830:Genetics 784:27717955 663:27927898 633:Genetics 620:14237908 529:Genetics 411:Genotype 400:See also 322:GAMETES 285:GAMETES 203:genotype 195:heredity 187:genetics 181:Overview 167:genotype 86:genetics 851:History 846:Outline 792:6017487 654:5161265 611:2165333 209:History 175:alleles 171:diploid 136:cloning 117:meiosis 47:improve 1017:Europe 1002:Africa 936:Fields 922:Allele 897:Genome 790:  782:  774:  706:  696:  661:  651:  618:  608:  600:  537:  514:  485:  193:, and 36:, but 1142:Lists 1022:Italy 861:Index 788:S2CID 752:(PDF) 393:yyrr 390:Yyrr 387:yyRr 384:YyRr 379:Yyrr 376:YYrr 373:YyRr 370:YYRr 365:yyRr 362:YyRr 359:yyRR 356:YyRR 351:YyRr 348:YYRr 345:YyRR 342:YYRR 237:Pisum 113:genes 780:PMID 772:ISSN 722:link 704:OCLC 694:ISBN 659:PMID 616:PMID 598:ISSN 535:ISBN 512:ISBN 483:ISBN 201:and 169:. 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Index

references
inline citations
improve
introducing
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genetics
Mendelian inheritance
Gregor Mendel
molecular biology
eukaryotes
genetic linkage
genes
meiosis
chromosomes
plant improvement
genetic code
cloning
restriction enzymes
reverse genetics
molecular genetics
gene
genotype
diploid
alleles
genetics
genetic variation
heredity
phenotype
genotype
Gregor Mendel's

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