20:
211:, which was discovered to have a crystal structure, was one of the initial members of the lipocalins protein superfamily, which has since grown significantly. It is a blue pigment protein that can be clearly identified by its amino acid sequence and crystal structure. The bilin-binding protein is predominantly present in
222:
Although it has recently been discovered that three swallowtail butterfly larval color patterns are correlated with the combination of bilin-binding protein and the yellow-related gene, additional physiological activities are still unknown. Normally, insect bilins are joined to proteins to create a
158:
Most photosynthetic, oxygen-producing organisms contain the positive chlorophyll biosynthesis regulator GENOMES UNCOUPLED 4 (GUN4). Research suggests that GUN4 regulates chlorophyll synthesis, by activating the enzyme
238:
Bilin-binding protein is a member of the lipocalin family, which includes extracellular proteins with a number of molecular ligand features in common, including the ability to bind tiny, primarily
980:
544:"Mass spectrometrical analysis of bilin-binding protein from the wing of Hebomoia glaucippe (Linnaeus, 1758) (Lepidoptera: Pieridae): Proteomics and 2-DE"
687:"Butterfly wings, a new site of porphyrin synthesis and cleavage: Studies on the expression of the lipocalin bilin-binding protein in Pieris brassicae"
497:"Butterfly wings, a new site of porphyrin synthesis and cleavage: Studies on the expression of the lipocalin bilin-binding protein in Pieris brassicae"
250:
family have mostly been classified as transport proteins, but it is clear that they also perform a range of other tasks, including retinol transport,
878:
1005:
640:"cDNA sequences of two biliproteins, BP1 and BP2, from the cabbage white butterfly, Pieris rapae and their tissue- and stage-specific accumulation"
593:"cDNA sequences of two biliproteins, BP1 and BP2, from the cabbage white butterfly, Pieris rapae and their tissue- and stage-specific accumulation"
1144:
833:
1209:
766:
207:
synthesis and cleavage in insect wings, which has been demonstrated here for the first time. The bilin-binding protein from
638:
Kim, Hong Ja; Yun, Chi Young; Han, Yeon Soo; Lee, In Hee; Kang, Young Jin; Jin, Byung Rae; Seo, Sook Jae (2006-01-01).
591:
Kim, Hong Ja; Yun, Chi Young; Han, Yeon Soo; Lee, In Hee; Kang, Young Jin; Jin, Byung Rae; Seo, Sook Jae (2006-01-01).
1246:
227:
and other insects. The presence of the blue and yellow pigments contributes to the blue-green hue of some
759:
686:
639:
592:
496:
1251:
172:
738:
399:"Phosphorylation of GENOMES UNCOUPLED 4 Alters Stimulation of Mg Chelatase Activity in Angiosperms"
1256:
1074:
752:
123:
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1080:
543:
134:
215:, fat body, and epidermis in the last instar larval and in the wings of the adult insect of
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8:
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1021:
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239:
160:
1186:
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during wing development is still unknown, as is the existence of an active pathway for
45:
985:
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Richter AS, Hochheuser C, Fufezan C, Heinze L, Kuhnert F, Grimm B (November 2016).
383:
363:
311:
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217:
208:
196:
448:"Structural basis of bilin binding by the chlorophyll biosynthesis regulator GUN4"
367:
1165:
923:
868:
808:
734:
119:
104:
80:. Bilins can range in color from red, orange, yellow or brown to blue or green.
1098:
942:
918:
702:
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512:
141:
354:
Oxford GS, Gillespie RG (1998). "Evolution and ecology of spider coloration".
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transmission. There is a lot of structural and functional variation in the
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130:
88:
65:
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Hu JH, Chang JW, Xu T, Wang J, Wang X, Lin R, et al. (October 2021).
1116:
813:
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228:
224:
200:
144:, which is responsible for the green color of the Green Huntsman Spider,
137:
126:
414:
164:
1134:
990:
896:
855:
803:
286:
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232:
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synthesis and cleavage where bilin is portrayed; the expression of the
115:
61:
542:
Bae, Narkhyun; Lödl, Martin; Pollak, Arnold; Lubec, Gert (July 2012).
933:
905:
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is an intermediate in the biosynthesis and uroporphyrinogen III from
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331:"Bilin | Photosynthesis, Chlorophyll, Carotenoids | Britannica"
110:
Examples of bilins are found in animals (cardinal examples are
100:
57:
19:
396:
73:
950:
182:
129:, in algae and plants. In plants, bilins also serve as the
96:
53:
48:
formed in many organisms as a metabolic product of certain
27:
171:. Bilins noncovalently bind to CrGUN4, an algal GUN4 from
83:
In chemical terms, bilins are linear arrangements of four
223:
variety of biliproteins that have been identified in
541:
347:
1238:
685:Sehringer, Bernd; Kayser, Hartmut (2006-06-01).
495:Sehringer, Bernd; Kayser, Hartmut (2006-06-01).
52:. Bilin (also called bilichrome) was named as a
684:
494:
353:
1043:
760:
445:
637:
590:
235:are thought to work together as camouflage.
26:, a yellow bilin, is a breakdown product of
774:
767:
753:
737:at the U.S. National Library of Medicine
691:Insect Biochemistry and Molecular Biology
644:Insect Biochemistry and Molecular Biology
597:Insect Biochemistry and Molecular Biology
559:
501:Insect Biochemistry and Molecular Biology
471:
422:
262:family, both within and between species.
175:, which has been shown to participate in
140:. An example of an invertebrate bilin is
183:Bilin-binding protein in butterfly wings
18:
1239:
748:
163:, which catalyzes the insertion of
13:
187:Butterfly wings are a new site of
14:
1273:
728:
254:cryptic coloring, olfaction, and
231:larvae. Blue pigments and yellow
60:, but can also be found in lower
678:
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1:
368:10.1146/annurev.ento.43.1.619
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7:
356:Annual Review of Entomology
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10:
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703:10.1016/j.ibmb.2006.03.005
656:10.1016/j.ibmb.2005.10.006
609:10.1016/j.ibmb.2005.10.006
513:10.1016/j.ibmb.2006.03.005
95:is a breakdown product of
16:Class of chemical compound
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1004:
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195:bilin-binding protein in
173:Chlamydomonas reinhardtii
122:, the chromophore of the
981:Magnesium protoporphyrin
739:Medical Subject Headings
91:). In human metabolism,
561:10.1002/elps.201100569
199:. The function of the
124:photosynthetic pigment
30:
1081:Protoporphyrinogen IX
135:photoreceptor protein
22:
1174:Bacteriochlorophyll
1153:Bacteriochlorophyll
177:retrograde signaling
147:Micrommata virescens
1247:Biological pigments
1187:Isobacteriochlorins
1022:Protochlorophyllide
996:Zinc protoporphyrin
415:10.1104/pp.16.01036
161:Magnesium chelatase
46:biological pigments
1067:Coproporphyrinogen
335:www.britannica.com
31:
1234:
1233:
1230:
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1226:
1225:
1030:
1029:
986:Protoporphyrin IX
914:Adenosylcobalamin
891:
890:
887:
886:
864:Phycoerythrobilin
554:(12): 1787–1794.
458:(10): 2083–2091.
297:Phycoerythrobilin
246:. Members of the
169:Protoporphyrin IX
1269:
1252:Organic pigments
1200:Sirohydrochlorin
1166:Bacteriochlorins
1053:Uroporphyrinogen
1041:
1040:
939:
938:
902:
901:
846:Phytochromobilin
839:
838:
792:
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755:
746:
745:
723:
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682:
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409:(3): 1578–1595.
403:Plant Physiology
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292:Phycobiliprotein
218:Pieris brassicae
209:Pieris brassicae
197:Pieris brassicae
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1036:
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1006:Phytoporphyrins
1000:
943:Protoporphyrins
928:
924:Methylcobalamin
883:
879:Phycoviolobilin
869:Phycocyanobilin
850:
828:
809:Stercobilinogen
787:
779:
773:
731:
726:
683:
679:
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589:
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548:Electrophoresis
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242:compounds like
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120:phycocyanobilin
105:porphobilinogen
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1099:Chlorophyllide
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1045:Porphyrinogens
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919:Cyanocobalamin
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1257:Tetrapyrroles
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874:Phycourobilin
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131:photopigments
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89:tetrapyrroles
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78:cyanobacteria
75:
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68:, as well as
67:
66:invertebrates
63:
59:
55:
51:
47:
43:
42:bile pigments
39:
35:
29:
25:
21:
1262:Biomolecules
1175:
1154:
1145:
1139:
1127:
1121:
1109:
1103:
1015:
1014:Chlorophyll
973:
967:
961:
955:
819:Urobilinogen
784:
694:
690:
680:
650:(1): 54–62.
647:
643:
633:
603:(1): 54–62.
600:
596:
586:
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455:
451:
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406:
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338:. Retrieved
334:
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252:invertebrate
237:
229:lepidopteran
216:
186:
157:
145:
109:
82:
41:
37:
33:
32:
1117:Chlorophyll
856:Phycobilins
834:Phytobilins
814:Stercobilin
302:Stercobilin
282:Biliprotein
233:carotenoids
225:Lepidoptera
201:biliprotein
138:phytochrome
127:phycocyanin
62:vertebrates
56:pigment of
1241:Categories
1135:Pheophytin
1037:porphyrins
991:Pterobilin
934:Porphyrins
906:Corrinoids
897:Macrocycle
804:Biliverdin
362:: 619–43.
340:2024-05-03
318:References
287:Phycobilin
277:Biliverdin
240:lipophilic
116:biliverdin
50:porphyrins
799:Bilirubin
775:Types of
711:0965-1748
664:0965-1748
617:0965-1748
521:0965-1748
272:Bilirubin
260:lipocalin
256:pheromone
248:lipocalin
213:hemolymph
205:porphyrin
193:lipocalin
189:porphyrin
154:In plants
112:bilirubin
93:bilirubin
70:red algae
24:Bilirubin
1210:Corphins
1195:Siroheme
1091:Chlorins
824:Urobilin
788:(Linear)
719:16731344
672:16360950
625:16360950
570:22740467
529:16731344
482:34382282
433:27688621
376:15012400
307:Urobilin
266:See also
72:, green
1035:Reduced
785:Bilanes
578:2485781
473:8442963
424:5100749
384:6963733
244:retinol
133:of the
118:), and
87:rings (
85:pyrrole
58:mammals
38:bilanes
741:(MeSH)
717:
709:
670:
662:
623:
615:
576:
568:
527:
519:
480:
470:
431:
421:
382:
374:
101:bilane
74:plants
34:Bilins
735:Bilin
574:S2CID
380:S2CID
167:into
951:Heme
715:PMID
707:ISSN
668:PMID
660:ISSN
621:PMID
613:ISSN
566:PMID
525:PMID
517:ISSN
478:PMID
429:PMID
372:PMID
114:and
97:heme
76:and
54:bile
44:are
28:heme
1075:III
1061:III
699:doi
652:doi
605:doi
556:doi
509:doi
468:PMC
460:doi
419:PMC
411:doi
407:172
364:doi
40:or
1243::
1143:,
1125:,
1107:,
1073:,
1059:,
971:,
965:,
959:,
713:.
705:.
695:36
693:.
689:.
666:.
658:.
648:36
646:.
642:.
619:.
611:.
601:36
599:.
595:.
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552:33
550:.
546:.
523:.
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505:36
503:.
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476:.
466:.
456:30
454:.
450:.
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417:.
405:.
401:.
378:.
370:.
360:43
358:.
333:.
179:.
165:Mg
150:.
107:.
64:,
36:,
1176:a
1155:c
1149:)
1146:b
1140:a
1137:(
1131:)
1128:b
1122:a
1119:(
1113:)
1110:b
1104:a
1101:(
1077:)
1071:I
1069:(
1063:)
1057:I
1055:(
1016:c
977:)
974:o
968:a
962:c
956:b
953:(
768:e
761:t
754:v
721:.
701::
674:.
654::
627:.
607::
580:.
558::
531:.
511::
484:.
462::
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413::
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366::
343:.
220:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
