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Anterior pituitary

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349: 361: 280: 1428: 1448: 29: 299:). It is composed of three lobes: the anterior, intermediate, and posterior lobes. In many animals, these lobes are distinct. However, in humans, the intermediate lobe is but a few cell layers thick and indistinct; as a result, it is often considered part of the anterior pituitary. In all animals, the fleshy, glandular anterior pituitary is distinct from the 459:, giving rise to the anterior pituitary. The anterior wall of Rathke's pouch proliferates, filling most of the pouch to form the pars distalis and the pars tuberalis. The posterior wall of the anterior pituitary forms the pars intermedia. Its formation from the soft tissues of the upper palate contrasts with the posterior pituitary, which originates from 1154:(FSH). This shows that the anterior pituitary gland is involved in behavioral functions as well as being part of a larger pathway for stress responses. It is also known that (HPA) hormones are related to certain skin diseases and skin homeostasis. There is evidence linking hyperactivity of HPA hormones to stress-related skin diseases and skin tumors. 1951:
Pendleton, Neil; Punab, Margus; Silman, Alan J; Vanderschueren, Dirk; Rockwood, Kenneth; Wu, Frederick C W; European Male Aging Study Group (May 2011). "Frailty in relation to variations in hormone levels of the hypothalamic-pituitary-testicular axis in older men: results from the European male aging study".
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Tajar, Abdelouahid; O'Connell, Matthew D L; Mitnitski, Arnold B; O'Neill, Terence W; Searle, Samuel D; Huhtaniemi, Ilpo T; Finn, Joseph D; Bartfai, György; Boonen, Steven; Casanueva, Felipe F; Forti, Gianni; Giwercman, Aleksander; Han, Thang S; Kula, Krzysztof; Labrie, Fernand; Lean, Michael E J;
389:), arising from the posterior lobe. (The pituitary stalk connects the hypothalamus to the posterior pituitary.) The function of the pars tuberalis is poorly understood. However, it has been seen to be important in receiving the endocrine signal in the form of 348: 341:
Nota bene: The terms "basophil" and "acidophil" are used by some books, whereas others prefer not to use these terms. This is due to the possible confusion with white blood cells, where one may also find basophils and acidophils.
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The pars distalis (distal part) comprises the majority of the anterior pituitary and is where the bulk of pituitary hormone production occurs. The pars distalis contains two types of cells, including
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Lin, M.T; Ho, L.T; and Uang, W.N. (1983) Effects of anterior pituitary hormones and their releasing hormones physiological and behavioral functions in rats. J. steroid Biochem. Vol. 19(1) 433-38.
421:(intermediate part) sits between the pars distalis and the posterior pituitary, forming the boundary between the anterior and posterior pituitaries. It is very small and indistinct in humans. 360: 1691:
Malendowicz, L.K; Rucinski, M; Belloni, A.S; Ziolkowska, A; and Nussdorfer, G.C. (2007) Leptin and the regulation of the hypothalamic-pituitary-adrenal axis. Int Rev Cytol. 263: 63-102.
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results from excessive secretion of growth hormone (GH) often being released by a pituitary adenoma. This disorder can cause disfigurement and possibly death and can lead to
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Le Tissier, P.R; Hodson, D.J; Lafont C; Fontanaud P; Schaeffer, M; Mollard, P. (2012) Anterior pituitary cell networks. Front Neuroendocrinol. Aug; 33(3):252-66
857:, at the base of the brain. At this site, these cells can release substances into small blood vessels that travel directly to the anterior pituitary gland (the 1348:
is characterized by a decreased secretion of hormones released by the anterior pituitary. For example, hypo-secretion of GH prior to puberty can be a cause of
893:(ACTH) and also to stimulate TSH, GH and LH release. Clinical evidence supports the experimental findings of the excitatory and inhibitory effects GABA has on 164: 1299:(tumour), which are benign apart from a tiny fraction. There are mainly three types of anterior pituitary tumors and their associated disorders. For example, 1718:
Racagni, G; Apud, J.A; Cocchi, D; Locatelli, V; Muller, E.E. (1982) GABAergic control of anterior pituitary hormone secretion. Life Sci. Aug 30;31(9):823-38.
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Dardente, H (2012). "Melatonin-dependent timing of seasonal reproduction by the pars tuberalis: pivotal roles for long daylengths and thyroid hormones".
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mechanisms were slowed, but injections of ACTH restored their performance. In addition, stress may delay the release of reproductive hormones such as
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Aside from hypothalamic control of the anterior pituitary, other systems in the body have been shown to regulate the anterior pituitary's function.
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response (fight or flight), anti-inflammatory effects, and inhibition of reproduction/growth. When the anterior pituitary gland is removed (
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is the condition where the pituitary secretes excessive amounts of hormones. This hypersecretion often results in the formation of a
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It has been shown that infant mice who were stroked with a paintbrush (simulating motherly care) had more release and binding of
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Hedge, G.A. (1977) Roles for the prostaglandins in the regulation of anterior pituitary secretion. Life Sci. Jan 1;20(1):17-33.
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can be caused by hypo-secretion of ACTH which, in turn, does not signal the adrenal cortex to produce a sufficient amount of
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The homeostatic maintenance of the anterior pituitary is crucial to our physiological well being. Increased plasma levels of
338:(beta cells). These cells all together produce hormones of the anterior pituitary and release them into the blood stream. 2631: 1259: 1167: 1075: 1010: 1763: 1671: 1666:
Nelson, R. J. (2011) An Introduction to Behavioral Endocrinology, 4th Edition. Sunderland, MA: Sinauer Associates, Inc.
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could be caused by the destruction or removal of the anterior pituitary tissue through traumatic brain injury, tumor,
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The anterior pituitary contains five types of endocrine cell, and they are defined by the hormones they secrete:
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and frailty in elderly men because of the eventual decrease in production of testosterone. This lower level of
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Aguilera, Greti (1998-10-01). "Corticotropin Releasing Hormone, Receptor Regulation and the Stress Response".
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Morgan, PJ; Williams, LM (1996). "The pars tuberalis of the pituitary: a gateway for neuroendocrine output".
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The release of GH, LH, and FSH are required for correct human development, including gonadal development.
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Wheater, P., Burkitt, H., Daniels, V. 1987. Functional Histology. Churchill Livingstone: New York.
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increase metabolism and induce cutaneous vasoconstriction, increased plasma levels also result in
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Aguilera, Greti (December 1994). "Regulation of Pituitary ACTH Secretion during Chronic Stress".
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Sone, M. and Osamura, R.Y. (2001) Leptin and the pituitary. Pituitary. Jan-Apr; 4(1-2): 15-23.
1323:. A third type of pituitary adenoma secretes excess ACTH, which in turn, causes an excess of 1079: 841:
Hormone secretion from the anterior pituitary gland is regulated by hormones secreted by the
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Dobson, H; R F Smith (2000-07-02). "What is stress, and how does it affect reproduction?".
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release in a cascading effect that ends with the production of glucocorticoids from the
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if increased beyond homeostatic levels through an increased metabolic mechanism only.
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secretion, dependent on GABA's site of action within the hypothalamic-pituitary axis.
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Ciccarelli, E; F Camanni (June 1996). "Diagnosis and drug therapy of prolactinoma".
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under stress conditions can cause the following: metabolic effects (mobilization of
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Microanatomy of the pars distalis showing chromophobes, basophils, and acidophils
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which drives the ongoing will to mate together with a constant production of
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Eosinophilic follicles are a common normal finding in the anterior pituitary.
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Median sagittal through the hypophysis of an adult monkey. Semidiagrammatic.
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Marieb, E. 2004. Human Anatomy and Physiology. Benjamin Cummings: New York.
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which are thought to stimulate and support the endocrine cell populations.
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in bones close in puberty. The most common type of pituitary tumour is a
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to release hormones, causing numerous cascading physiological responses.
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from the pineal gland which can also affect the secretion levels in the
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are named for their ability to act directly on target tissues or other
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and testosterone. In addition, melatonin may affect production of
2385: 1127: 1098:(ACTH) from the anterior pituitary gland. Then, this acts on the 456: 268: 1927:
Jung Eun Kim; Baik Kee Cho; Dae Ho Cho; Hyun Jeong Park (2013).
1214:, well-being and mood, muscle and bone strength, and metabolism. 1134:), bone re-absorption (calcium mobilization), activation of the 1758:(4th ed.). Sunderland, Massachusetts: Sinauer Associates. 1211: 1187: 985: 779: 689: 652: 300: 61: 1372:, among other causes. This disorder used to be referred to as 2515: 2490: 1496:
Eroschenko, Victor P.; Fiore, Mariano S. H. di (2013-01-01).
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Light information received by the eyes is transmitted to the
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Scacchi, Massimo; Francesco Cavagnini (2006). "Acromegaly".
1078:(HPA), the anterior pituitary gland has a large role in the 2207: 1202:(LH and FSH) caused by normal aging may be responsible for 1021: 942: 870: 814: 393:(a β subunit of TSH), informing the pars tuberalis of the 390: 71: 28: 2028: 1881: 1879: 1877: 1499:
DiFiore's Atlas of Histology with Functional Correlations
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The anterior pituitary plays a role in stress response.
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Secretion of hormones from the Anterior Pituitary Gland
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The Pituitary Network Association -- www.pituitary.org
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The anterior pituitary is composed of three regions:
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in response to light information transmitted to the
2247: 2071: 455:The pouch eventually loses its connection with the 1122:to slow the production of CRH and ACTH. Increased 1653: 1114:act back on the anterior pituitary gland and the 873:can either stimulate or inhibit the secretion of 2649: 2002:Juszczak, Marlena; Monika Michalska (2006). "". 1753: 1170:, the anterior pituitary gland also affects the 1082:'s stress response. Stress induces a release of 498:Hormones secreted by the anterior pituitary are 1885: 1823: 1495: 1307:, a hormone disorder shown in "giants" such as 1254:). Diminishing light stimulates the release of 825: 291:sits in a protective bony enclosure called the 2125:"Diagnosis and Treatment of Simmonds' Disease" 1772: 1624: 953:decreases with decreasing temperature values. 330:. The chromophils can be further divided into 2233: 2065: 1749: 1747: 1745: 1743: 1741: 1739: 1737: 1735: 1733: 1401:, meaning "glandular undergrowth", from the 1397:The anterior pituitary is also known as the 1756:An introduction to behavioral endocrinology 941:but through a decreased metabolism action. 432:The anterior pituitary is derived from the 2637:List of human endocrine organs and actions 2240: 2226: 2022: 1953:Journal of the American Geriatrics Society 1523:Ikegami, K; Iigo, M; Yoshimura, T (2013). 27: 2156: 2004:PostÄ™py Higieny I Medycyny DoĹ›wiadczalnej 1995: 1730: 1558: 1548: 1360:. This is a life-threatening condition. 385:(also known as the infundibular stalk or 243:The anterior pituitary regulates several 2116: 1829: 1781:Trends in Endocrinology & Metabolism 1778: 1581: 1433:The anterior pituitary is the anterior, 1276: 1210:can have other effects, such as reduced 1178:(GnRH), which stimulates the release of 922:through a mechanism involving increased 881:(GH) and can stimulate the secretion of 278: 2122: 1943: 1931:. National Research Foundation of Korea 1230:(GH) from the anterior pituitary gland. 1020:(CRH) from the hypothalamus stimulates 836: 224:, or the neurohypophysis) makes up the 2650: 859:hypothalamo-hypophyseal portal vessels 491:(TSH). It also contains non-endocrine 2221: 1502:. Lippincott Williams & Wilkins. 1334: 1281: 1031: 1491: 1489: 1419: 16:Anterior lobe of the pituitary gland 1474:Hypothalamic–pituitary–somatic axis 1327:to be secreted and is the cause of 1260:hypothalamic-pituitary-gonadal axis 1168:hypothalamic-pituitary-gonadal axis 1076:hypothalamic-pituitary-adrenal axis 1011:Hypothalamic-pituitary-adrenal axis 864: 236:, protruding off the bottom of the 13: 2284: 2177: 14: 2674: 2190: 2123:Summers, V. K. (September 1947). 1486: 1094:, which activates the release of 901:Effects of the anterior pituitary 436:, more specifically from that of 2086:10.2165/00003495-199651060-00004 1965:10.1111/j.1532-5415.2011.03398.x 1596:10.1111/j.1365-2826.2011.02250.x 1446: 1426: 359: 347: 232:, is located at the base of the 1920: 1832:Frontiers in Neuroendocrinology 1721: 1712: 1354:secondary adrenal insufficiency 1084:corticotropin-releasing hormone 1018:Corticotropin releasing hormone 1703: 1694: 1685: 1676: 1618: 1575: 1516: 1176:gonadotropin-releasing hormone 427: 283:The anterior pituitary complex 1: 1898:10.1016/s0378-4320(00)00080-4 1793:10.1016/S1043-2760(98)00079-4 1584:Journal of Neuroendocrinology 1479: 1311:, where it occurs before the 1198:. The decrease in release of 2129:Postgraduate Medical Journal 1550:10.1371/journal.pone.0058482 1392: 1184:follicle-stimulating hormone 1174:. The hypothalamus releases 1152:follicle-stimulating hormone 955:follicle-stimulating hormone 849:in the hypothalamus project 826:Role in the endocrine system 629:Follicle-stimulating hormone 274: 216:lobe that together with the 7: 1889:Animal Reproduction Science 1455: 1096:adrenocorticotropic hormone 891:adrenocorticotropic hormone 883:thyroid-stimulating hormone 590:Thyroid-stimulating hormone 543:Adrenocorticotropic hormone 466: 10: 2679: 1459: 1387: 1338: 1285: 1136:sympathetic nervous system 829: 2602: 2579: 2541: 2489: 2467: 2439: 2430: 2407: 2384: 2342: 2265: 2256: 2197:Histology image: 14002loa 2043:10.1007/s11102-006-0409-4 1754:Nelson, Randy J. (2011). 1376:but now according to the 889:are now known to inhibit 440:, part of the developing 170: 158: 146: 134: 121: 109: 97: 92:lobus anterior hypophysis 85: 80: 70: 60: 43: 38: 26: 21: 22:Anterior pituitary gland 2305:Somatomammotrophic cell 2141:10.1136/pgmj.23.263.441 1627:Reviews of Reproduction 1252:suprachiasmatic nucleus 1054:Release of the hormone 741:carbohydrate metabolism 493:folliculostellate cells 228:(hypophysis) which, in 1844:10.1006/frne.1994.1013 1462:anatomical terminology 1166:Operating through the 1074:Operating through the 933:. Increased levels of 284: 172:Anatomical terminology 2203:Embryology at unc.edu 1639:10.1530/ror.0.0010153 1277:Clinical significance 1080:neuroendocrine system 957:(FSH) also may cause 806:prostatic hyperplasia 282: 247:processes, including 2620:Organ of Zuckerkandl 2610:Enteroendocrine cell 1319:which hypersecretes 847:Neuroendocrine cells 837:Hypothalamic control 297:Turkish chair/saddle 66:Superior hypophyseal 2663:Human head and neck 2399:Parafollicular cell 1541:2013PLoSO...858482I 1248:circadian pacemaker 1180:luteinizing hormone 1172:reproductive system 1148:luteinizing hormone 1130:, fatty acids, and 978:luteinising hormone 908:Thermal homeostasis 875:luteinizing hormone 666:Luteinizing hormone 659:reproductive system 305:posterior pituitary 303:composition of the 222:posterior pituitary 2543:Islets of pancreas 2317:Corticotropic cell 1892:. 60–61: 743–752. 1460:This article uses 1335:Decreased activity 1282:Increased activity 1223:Tactile responding 1144:avoidance learning 1032:Behavioral effects 334:(alpha cells) and 285: 198:anterior pituitary 2645: 2644: 2485: 2484: 2409:Parathyroid gland 2380: 2379: 2322:Gonadotropic cell 2295:Somatotropic cell 1469:Triple bolus test 1420:Additional images 1378:Diseases Database 1374:Simmonds' disease 1329:Cushing's disease 1313:epiphyseal plates 1297:pituitary adenoma 1239:Circadian rhythms 1142:) in rats, their 1120:negative feedback 1058:is essential for 821: 820: 735:Promotes growth; 579:mineralocorticoid 324:chromophobe cells 200:(also called the 186: 185: 181: 2670: 2658:Endocrine system 2594:Corpora arenacea 2459:Zona reticularis 2454:Zona fasciculata 2449:Zona glomerulosa 2437: 2436: 2334:Chromophobe cell 2327:Thyrotropic cell 2263: 2262: 2250:endocrine system 2242: 2235: 2228: 2219: 2218: 2171: 2170: 2160: 2135:(263): 441–443. 2120: 2114: 2113: 2069: 2063: 2062: 2026: 2020: 2019: 1999: 1993: 1992: 1947: 1941: 1940: 1938: 1936: 1924: 1918: 1917: 1883: 1872: 1871: 1827: 1821: 1820: 1776: 1770: 1769: 1751: 1728: 1725: 1719: 1716: 1710: 1707: 1701: 1698: 1692: 1689: 1683: 1680: 1674: 1664: 1651: 1650: 1622: 1616: 1615: 1579: 1573: 1572: 1562: 1552: 1520: 1514: 1513: 1493: 1450: 1430: 1382:Sheehan syndrome 1352:. In addition, 1293:Hyperpituitarism 1288:Hyperpituitarism 967:Gonadal function 865:Other mechanisms 622:thyroid hormones 528:Secretory cells 513: 512: 508:endocrine glands 500:trophic hormones 363: 351: 328:chromophil cells 194:endocrine system 178:edit on Wikidata 175: 31: 19: 18: 2678: 2677: 2673: 2672: 2671: 2669: 2668: 2667: 2648: 2647: 2646: 2641: 2598: 2575: 2537: 2481: 2477:Chromaffin cell 2463: 2426: 2403: 2394:Follicular cell 2376: 2357:Median eminence 2338: 2275:Pars intermedia 2258:Pituitary gland 2252: 2248:Anatomy of the 2246: 2193: 2180: 2178:Further reading 2175: 2174: 2121: 2117: 2070: 2066: 2027: 2023: 2000: 1996: 1948: 1944: 1934: 1932: 1925: 1921: 1884: 1875: 1828: 1824: 1777: 1773: 1766: 1752: 1731: 1726: 1722: 1717: 1713: 1708: 1704: 1699: 1695: 1690: 1686: 1681: 1677: 1665: 1654: 1623: 1619: 1580: 1576: 1521: 1517: 1510: 1494: 1487: 1482: 1465: 1458: 1451: 1442: 1439:pituitary gland 1431: 1422: 1412:("under"), and 1399:adenohypophysis 1395: 1390: 1362:Hypopituitarism 1346:Hypopituitarism 1343: 1341:Hypopituitarism 1337: 1309:AndrĂ© the Giant 1290: 1284: 1279: 1112:glucocorticoids 1104:glucocorticoids 1034: 982:ovulation cycle 937:also result in 903: 867: 855:median eminence 839: 834: 828: 802:spermatogenesis 504:Tropic hormones 469: 444:in the embryo. 430: 419:pars intermedia 414:Pars intermedia 383:pituitary stalk 367: 364: 355: 352: 289:pituitary gland 277: 226:pituitary gland 202:adenohypophysis 182: 34: 17: 12: 11: 5: 2676: 2666: 2665: 2660: 2643: 2642: 2640: 2639: 2634: 2629: 2624: 2623: 2622: 2612: 2606: 2604: 2600: 2599: 2597: 2596: 2591: 2585: 2583: 2577: 2576: 2574: 2573: 2568: 2563: 2558: 2553: 2547: 2545: 2539: 2538: 2536: 2535: 2534: 2533: 2528: 2526:Granulosa cell 2523: 2513: 2512: 2511: 2506: 2495: 2493: 2487: 2486: 2483: 2482: 2480: 2479: 2473: 2471: 2465: 2464: 2462: 2461: 2456: 2451: 2445: 2443: 2434: 2428: 2427: 2425: 2424: 2419: 2413: 2411: 2405: 2404: 2402: 2401: 2396: 2390: 2388: 2382: 2381: 2378: 2377: 2375: 2374: 2372:Herring bodies 2369: 2364: 2359: 2354: 2348: 2346: 2340: 2339: 2337: 2336: 2331: 2330: 2329: 2324: 2319: 2309: 2308: 2307: 2302: 2300:Prolactin cell 2297: 2290:Acidophil cell 2287: 2282: 2280:Pars tuberalis 2277: 2271: 2269: 2260: 2254: 2253: 2245: 2244: 2237: 2230: 2222: 2216: 2215: 2210: 2205: 2200: 2192: 2191:External links 2189: 2188: 2187: 2184: 2179: 2176: 2173: 2172: 2115: 2080:(6): 954–965. 2064: 2037:(4): 297–303. 2021: 1994: 1959:(5): 814–821. 1942: 1919: 1873: 1838:(4): 321–350. 1822: 1787:(8): 329–336. 1771: 1765:978-0878936205 1764: 1729: 1720: 1711: 1702: 1693: 1684: 1675: 1672:978-0878936205 1652: 1617: 1574: 1515: 1508: 1484: 1483: 1481: 1478: 1477: 1476: 1471: 1457: 1454: 1453: 1452: 1445: 1443: 1432: 1425: 1421: 1418: 1394: 1391: 1389: 1386: 1339:Main article: 1336: 1333: 1286:Main article: 1283: 1280: 1278: 1275: 1274: 1273: 1272: 1271: 1240: 1234: 1233: 1232: 1231: 1228:growth hormone 1224: 1218: 1217: 1216: 1215: 1164: 1158: 1157: 1156: 1155: 1140:hypophysectomy 1100:adrenal cortex 1072: 1066: 1065: 1064: 1063: 1052: 1051:Breast-feeding 1046: 1045: 1044: 1043: 1040: 1033: 1030: 1026:adrenal cortex 1006: 1005: 1004: 1003: 971: 970: 969: 968: 912: 911: 910: 909: 902: 899: 887:Prostaglandins 879:growth hormone 866: 863: 838: 835: 830:Main article: 827: 824: 819: 818: 808: 786: 776:mammary glands 769: 764: 759: 756: 753: 750: 744: 743: 733: 731:adipose tissue 724: 719: 714: 711: 708: 705: 703:Growth hormone 699: 698: 692: 687: 682: 677: 674: 671: 668: 662: 661: 655: 650: 645: 640: 637: 634: 631: 625: 624: 618: 613: 608: 603: 598: 595: 592: 586: 585: 575:glucocorticoid 571: 566: 561: 556: 551: 548: 547:Corticotropin 545: 539: 538: 535: 532: 529: 526: 523: 520: 517: 483:(LH and FSH); 468: 465: 446:Rathke's pouch 438:Rathke's pouch 429: 426: 425: 424: 423: 422: 415: 409: 408: 407: 406: 379:pars tuberalis 375: 374:Pars tuberalis 369: 368: 365: 358: 356: 353: 346: 320: 319: 318: 317: 276: 273: 184: 183: 174: 168: 167: 162: 156: 155: 150: 144: 143: 138: 132: 131: 126: 119: 118: 113: 107: 106: 101: 95: 94: 89: 83: 82: 78: 77: 74: 68: 67: 64: 58: 57: 54:Rathke's pouch 47: 41: 40: 36: 35: 32: 24: 23: 15: 9: 6: 4: 3: 2: 2675: 2664: 2661: 2659: 2656: 2655: 2653: 2638: 2635: 2633: 2630: 2628: 2625: 2621: 2618: 2617: 2616: 2613: 2611: 2608: 2607: 2605: 2601: 2595: 2592: 2590: 2587: 2586: 2584: 2582: 2578: 2572: 2569: 2567: 2564: 2562: 2559: 2557: 2554: 2552: 2549: 2548: 2546: 2544: 2540: 2532: 2531:Corpus luteum 2529: 2527: 2524: 2522: 2521:Theca interna 2519: 2518: 2517: 2514: 2510: 2507: 2505: 2502: 2501: 2500: 2497: 2496: 2494: 2492: 2488: 2478: 2475: 2474: 2472: 2470: 2466: 2460: 2457: 2455: 2452: 2450: 2447: 2446: 2444: 2442: 2438: 2435: 2433: 2432:Adrenal gland 2429: 2423: 2420: 2418: 2415: 2414: 2412: 2410: 2406: 2400: 2397: 2395: 2392: 2391: 2389: 2387: 2383: 2373: 2370: 2368: 2365: 2363: 2360: 2358: 2355: 2353: 2350: 2349: 2347: 2345: 2341: 2335: 2332: 2328: 2325: 2323: 2320: 2318: 2315: 2314: 2313: 2312:Basophil cell 2310: 2306: 2303: 2301: 2298: 2296: 2293: 2292: 2291: 2288: 2286: 2285:Pars distalis 2283: 2281: 2278: 2276: 2273: 2272: 2270: 2268: 2264: 2261: 2259: 2255: 2251: 2243: 2238: 2236: 2231: 2229: 2224: 2223: 2220: 2214: 2211: 2209: 2206: 2204: 2201: 2198: 2195: 2194: 2185: 2182: 2181: 2168: 2164: 2159: 2154: 2150: 2146: 2142: 2138: 2134: 2130: 2126: 2119: 2111: 2107: 2103: 2099: 2095: 2091: 2087: 2083: 2079: 2075: 2068: 2060: 2056: 2052: 2048: 2044: 2040: 2036: 2032: 2025: 2017: 2013: 2009: 2005: 1998: 1990: 1986: 1982: 1978: 1974: 1970: 1966: 1962: 1958: 1954: 1946: 1930: 1923: 1915: 1911: 1907: 1903: 1899: 1895: 1891: 1890: 1882: 1880: 1878: 1869: 1865: 1861: 1857: 1853: 1849: 1845: 1841: 1837: 1833: 1826: 1818: 1814: 1810: 1806: 1802: 1798: 1794: 1790: 1786: 1782: 1775: 1767: 1761: 1757: 1750: 1748: 1746: 1744: 1742: 1740: 1738: 1736: 1734: 1724: 1715: 1706: 1697: 1688: 1679: 1673: 1669: 1663: 1661: 1659: 1657: 1648: 1644: 1640: 1636: 1633:(3): 153–61. 1632: 1628: 1621: 1613: 1609: 1605: 1601: 1597: 1593: 1590:(2): 249–66. 1589: 1585: 1578: 1570: 1566: 1561: 1556: 1551: 1546: 1542: 1538: 1535:(3): e58482. 1534: 1530: 1526: 1519: 1511: 1509:9781451113419 1505: 1501: 1500: 1492: 1490: 1485: 1475: 1472: 1470: 1467: 1466: 1463: 1449: 1444: 1440: 1436: 1429: 1424: 1423: 1417: 1415: 1411: 1407: 1404: 1400: 1385: 1383: 1380:it is called 1379: 1375: 1371: 1367: 1363: 1359: 1355: 1351: 1347: 1342: 1332: 1330: 1326: 1322: 1318: 1314: 1310: 1306: 1302: 1298: 1294: 1289: 1269: 1265: 1261: 1257: 1253: 1249: 1245: 1241: 1238: 1237: 1236: 1235: 1229: 1225: 1222: 1221: 1220: 1219: 1213: 1209: 1205: 1201: 1200:gonadotropins 1197: 1193: 1189: 1185: 1181: 1177: 1173: 1169: 1165: 1162: 1161: 1160: 1159: 1153: 1149: 1145: 1141: 1137: 1133: 1129: 1125: 1121: 1117: 1113: 1109: 1105: 1101: 1097: 1093: 1089: 1085: 1081: 1077: 1073: 1070: 1069: 1068: 1067: 1061: 1057: 1053: 1050: 1049: 1048: 1047: 1041: 1038: 1037: 1036: 1035: 1029: 1027: 1023: 1019: 1014: 1013: 1012: 1008:Main article 1001: 1000: 999: 998: 997: 995: 991: 987: 983: 979: 975: 966: 965: 964: 963: 962: 960: 956: 952: 948: 944: 940: 936: 932: 929: 925: 921: 917: 907: 906: 905: 904: 898: 896: 892: 888: 884: 880: 876: 872: 862: 860: 856: 852: 848: 844: 833: 823: 816: 812: 809: 807: 803: 799: 795: 791: 788:Secretion of 787: 785: 781: 777: 773: 770: 768: 765: 763: 760: 757: 754: 751: 749: 746: 745: 742: 738: 734: 732: 728: 725: 723: 720: 718: 715: 712: 709: 707:Somatotropin 706: 704: 701: 700: 696: 693: 691: 688: 686: 683: 681: 678: 676:Glycoprotein 675: 672: 669: 667: 664: 663: 660: 656: 654: 651: 649: 646: 644: 641: 639:Glycoprotein 638: 635: 632: 630: 627: 626: 623: 620:Secretion of 619: 617: 616:Thyroid gland 614: 612: 609: 607: 604: 602: 599: 596: 593: 591: 588: 587: 584: 580: 576: 573:Secretion of 572: 570: 569:Adrenal gland 567: 565: 562: 560: 559:Corticotrophs 557: 555: 552: 549: 546: 544: 541: 540: 536: 533: 530: 527: 524: 521: 518: 515: 514: 511: 509: 505: 501: 496: 494: 490: 486: 485:corticotropes 482: 478: 474: 464: 462: 461:neuroectoderm 458: 453: 451: 447: 443: 439: 435: 420: 416: 413: 412: 411: 410: 404: 400: 396: 392: 388: 384: 380: 376: 373: 372: 371: 370: 362: 357: 350: 345: 344: 343: 339: 337: 333: 329: 325: 316:Pars distalis 315: 314: 313: 312: 311: 308: 306: 302: 298: 294: 293:sella turcica 290: 281: 272: 270: 267:that measure 266: 262: 258: 254: 250: 246: 245:physiological 241: 239: 235: 231: 227: 223: 219: 215: 211: 207: 206:pars anterior 203: 199: 195: 191: 179: 173: 169: 166: 163: 161: 157: 154: 151: 149: 145: 142: 139: 137: 133: 130: 127: 124: 120: 117: 114: 112: 108: 105: 102: 100: 96: 93: 90: 88: 84: 79: 75: 73: 69: 65: 63: 59: 55: 51: 48: 46: 42: 37: 30: 25: 20: 2581:Pineal gland 2571:Epsilon cell 2509:Sertoli cell 2422:Oxyphil cell 2352:Pars nervosa 2266: 2132: 2128: 2118: 2077: 2073: 2067: 2034: 2030: 2024: 2007: 2003: 1997: 1956: 1952: 1945: 1933:. Retrieved 1922: 1887: 1835: 1831: 1825: 1784: 1780: 1774: 1755: 1723: 1714: 1705: 1696: 1687: 1678: 1630: 1626: 1620: 1587: 1583: 1577: 1532: 1528: 1518: 1498: 1437:lobe of the 1416:("growth"). 1413: 1409: 1405: 1398: 1396: 1366:tuberculosis 1344: 1317:prolactinoma 1291: 1244:pineal gland 1208:testosterone 1196:testosterone 1116:hypothalamus 1092:hypothalamus 1015: 1009: 1007: 976:, primarily 974:Gonadotropes 972: 947:hyperthermia 931:vasodilation 920:hyperthermia 913: 868: 843:hypothalamus 840: 832:Hypothalamus 822: 794:progesterone 758:Polypeptide 752:Lactotropin 717:Somatotrophs 713:Polypeptide 680:Gonadotrophs 643:Gonadotrophs 601:Glycoprotein 594:Thyrotropin 519:Other names 497: 481:gonadotropes 473:somatotropes 470: 454: 431: 403:pineal gland 387:infundibulum 386: 340: 321: 309: 296: 286: 257:reproduction 242: 238:hypothalamus 205: 201: 197: 187: 141:A11.1.00.002 129:birnlex_1581 91: 2632:Development 2615:Paraganglia 2589:Pinealocyte 2504:Leydig cell 2010:: 431–438. 1408:("gland"), 1186:. Then the 1132:amino acids 1102:to produce 1088:vasopressin 1039:Development 959:hypothermia 939:hypothermia 762:Lactotrophs 697:production 695:Sex hormone 606:Thyrotrophs 554:Polypeptide 489:thyrotropes 487:(ACTH) and 477:lactotropes 452:in origin. 442:hard palate 428:Development 395:photoperiod 265:blood tests 81:Identifiers 76:Hypophyseal 50:Oral mucosa 2652:Categories 2566:Delta cell 2551:Alpha cell 2417:Chief cell 1480:References 1301:acromegaly 1086:(CRH) and 984:in female 924:metabolism 817:secretion 657:Growth of 525:Structure 522:Symbol(s) 450:ectodermal 332:acidophils 111:NeuroNames 2556:Beta cell 2367:Pituicyte 2344:Posterior 2149:0032-5473 2094:0012-6667 2051:1573-7403 2031:Pituitary 2016:1732-2693 1973:1532-5415 1906:0378-4320 1852:0091-3022 1801:1043-2760 1435:glandular 1393:Etymology 1321:prolactin 1305:gigantism 1268:prolactin 1256:melatonin 1204:impotence 1182:(LH) and 1150:(LH) and 1090:from the 1060:lactation 1056:prolactin 951:prolactin 928:cutaneous 877:(LH) and 798:lactation 790:estrogens 767:Acidophil 748:Prolactin 722:Acidophil 673:LH, ICSH 670:Lutropin 583:androgens 531:Staining 399:melatonin 336:basophils 275:Structure 261:lactation 218:posterior 210:glandular 208:) is the 45:Precursor 2627:Placenta 2499:Testicle 2267:Anterior 2167:20258051 2110:35481175 2059:17077948 1989:43285151 1981:21568952 1914:10844239 1868:24818312 1817:30175791 1809:18406298 1612:12723490 1604:22070540 1569:23505514 1529:PLOS ONE 1456:See also 1370:syphilis 1358:cortisol 1350:dwarfism 1325:cortisol 1264:estrogen 1246:via the 1192:estrogen 1190:produce 1124:cortisol 1110:. These 1108:cortisol 1106:such as 1002:HPA axis 990:androgen 784:prostate 710:GH, STH 685:Basophil 648:Basophil 611:Basophil 564:Basophil 516:Hormone 467:Function 448:is also 434:ectoderm 271:levels. 214:anterior 188:A major 123:NeuroLex 2561:PP cell 2469:Medulla 2386:Thyroid 2158:2529616 2102:8736617 1935:4 March 1860:7895891 1647:9414453 1560:3591342 1537:Bibcode 1388:History 1128:glucose 986:mammals 918:induce 885:(TSH). 853:to the 772:Ovaries 537:Effect 534:Target 479:(PRL); 457:pharynx 269:hormone 192:of the 104:D010903 39:Details 2491:Gonads 2441:Cortex 2165:  2155:  2147:  2108:  2100:  2092:  2057:  2049:  2014:  1987:  1979:  1971:  1912:  1904:  1866:  1858:  1850:  1815:  1807:  1799:  1762:  1670:  1645:  1610:  1602:  1567:  1557:  1506:  1414:physis 1406:adeno- 1212:libido 1188:gonads 1071:Stress 780:testes 690:Gonads 653:Gonads 475:(GH); 301:neural 259:, and 253:growth 249:stress 230:humans 220:lobe ( 196:, the 62:Artery 2603:Other 2516:Ovary 2362:Stalk 2106:S2CID 2074:Drugs 1985:S2CID 1864:S2CID 1813:S2CID 1608:S2CID 1403:Greek 1368:, or 1250:(the 1163:Aging 1118:with 994:sperm 949:and 851:axons 737:lipid 727:Liver 550:ACTH 234:brain 190:organ 176:[ 165:74627 87:Latin 2163:PMID 2145:ISSN 2098:PMID 2090:ISSN 2055:PMID 2047:ISSN 2012:ISSN 1977:PMID 1969:ISSN 1937:2014 1910:PMID 1902:ISSN 1856:PMID 1848:ISSN 1805:PMID 1797:ISSN 1760:ISBN 1668:ISBN 1643:PMID 1600:PMID 1565:PMID 1504:ISBN 1410:hypo 1194:and 1022:ACTH 943:ACTH 926:and 871:GABA 815:ACTH 813:and 755:PRL 739:and 636:FSH 597:TSH 581:and 417:The 391:TSHB 377:The 326:and 287:The 153:3855 136:TA98 99:MeSH 72:Vein 2153:PMC 2137:doi 2082:doi 2039:doi 1961:doi 1894:doi 1840:doi 1789:doi 1635:doi 1592:doi 1555:PMC 1545:doi 916:TSH 861:). 811:TSH 240:. 204:or 160:FMA 148:TA2 116:407 2654:: 2161:. 2151:. 2143:. 2133:23 2131:. 2127:. 2104:. 2096:. 2088:. 2078:51 2076:. 2053:. 2045:. 2033:. 2008:60 2006:. 1983:. 1975:. 1967:. 1957:59 1955:. 1908:. 1900:. 1876:^ 1862:. 1854:. 1846:. 1836:15 1834:. 1811:. 1803:. 1795:. 1783:. 1732:^ 1655:^ 1641:. 1629:. 1606:. 1598:. 1588:24 1586:. 1563:. 1553:. 1543:. 1531:. 1527:. 1488:^ 1331:. 1028:. 996:. 935:LH 895:GH 845:. 804:; 800:; 796:; 782:, 778:, 774:, 729:, 633:- 577:, 463:. 307:. 255:, 251:, 212:, 125:ID 2241:e 2234:t 2227:v 2169:. 2139:: 2112:. 2084:: 2061:. 2041:: 2035:9 2018:. 1991:. 1963:: 1939:. 1916:. 1896:: 1870:. 1842:: 1819:. 1791:: 1785:9 1768:. 1649:. 1637:: 1631:1 1614:. 1594:: 1571:. 1547:: 1539:: 1533:8 1512:. 1464:. 1441:. 1270:. 1062:. 792:/ 295:( 180:] 56:) 52:(

Index


Precursor
Oral mucosa
Rathke's pouch
Artery
Vein
Latin
MeSH
D010903
NeuroNames
407
NeuroLex
birnlex_1581
TA98
A11.1.00.002
TA2
3855
FMA
74627
Anatomical terminology
edit on Wikidata
organ
endocrine system
glandular
anterior
posterior
posterior pituitary
pituitary gland
humans
brain

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