Knowledge

Androgen receptor

Source 📝

1895: 604: 581: 503: 478: 2341: 610: 509: 2126:
transcriptional regulation of a number of genes via androgen responsive elements. This androgen response mechanism is perhaps best known and characterized in the context of male sexual differentiation and puberty, but plays a role in a variety of tissue types and processes. Upon binding to androgens, the androgen receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen-responsive genes.
1783: 31: 855: 862: 1898:
Normal function of the androgen receptor. Testosterone (T) enters the cell and, if 5-alpha-reductase is present, is converted into dihydrotestosterone (DHT). Upon steroid binding, the androgen receptor (AR) undergoes a conformational change and releases heat-shock proteins (hsps). Phosphorylation (P)
2314:
that affect receptor function, where fewer repeats leads to increased receptor sensitivity to circulating androgens and more repeats leads to decreased receptor sensitivity. Studies have shown that racial variation in CAG repeats exists, with African-Americans having fewer repeats than non-Hispanic
2153:, where it forms macromolacular protein condensates that might facilitate rapid gene regulation as consequence of local high protein concentrations together with other coregulators. Androgen receptors interact with other proteins in the nucleus, resulting in up- or down-regulation of specific 2125:
Androgens (also called androgenic hormones), such as testosterone or dihydrotestosterone, are understood to exert their primary effects through binding to an androgen receptor in the cytosol. The receptor is translocated to the nucleus upon androgen binding and ultimately results in the
3636:
Lu NZ, Wardell SE, Burnstein KL, Defranco D, Fuller PJ, Giguere V, et al. (December 2006). "International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors".
9400:"Activation function-1 domain of androgen receptor contributes to the interaction between subnuclear splicing factor compartment and nuclear receptor compartment. Identification of the p102 U5 small nuclear ribonucleoprotein particle-binding protein as a coactivator for the receptor" 2352:) of the human androgen receptor. Numbers above the bars refer to the amino acid residues that separate the domains starting from the N-terminus (left) to C-terminus (right). NTD = N-terminal domain, DBD = DNA-binding domain, LBD = ligand-binding domain, AF = activation function. 2327:
and the gene encoding for these receptors contain recurrent mutations, such as structural rearrangements and copy number changes, acquired in the progression of metastatic castration-resistant prostate cancer (mCRPC) treatment with therapy targeting these receptors (abiraterone,
57: 7713:
Niki T, Takahashi-Niki K, Taira T, Iguchi-Ariga SM, Ariga H (February 2003). "DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex".
8099:
Veldscholte J, Berrevoets CA, Brinkmann AO, Grootegoed JA, Mulder E (March 1992). "Anti-androgens and the mutated androgen receptor of LNCaP cells: differential effects on binding affinity, heat-shock protein interaction, and transcription activation".
6279:
Ayub M, Levell MJ (August 1989). "The effect of ketoconazole related imidazole drugs and antiandrogens on R 1881 binding to the prostatic androgen receptor and 5 alpha-dihydrotestosterone and cortisol binding to plasma proteins".
10176:
Matsuda T, Junicho A, Yamamoto T, Kishi H, Korkmaz K, Saatcioglu F, et al. (April 2001). "Cross-talk between signal transducer and activator of transcription 3 and androgen receptor signaling in prostate carcinoma cells".
7176:
Beauchemin AM, Gottlieb B, Beitel LK, Elhaji YA, Pinsky L, Trifiro MA (2001). "Cytochrome c oxidase subunit Vb interacts with human androgen receptor: a potential mechanism for neurotoxicity in spinobulbar muscular atrophy".
7801:
Bonaccorsi L, Muratori M, Carloni V, Marchiani S, Formigli L, Forti G, et al. (August 2004). "The androgen receptor associates with the epidermal growth factor receptor in androgen-sensitive prostate cancer cells".
1899:
occurs before or after steroid binding. The AR translocates to the nucleus where dimerization, DNA binding, and the recruitment of coactivators occur. Target genes are transcribed (mRNA) and translated into proteins.
5752:"Functional interactions of the AF-2 activation domain core region of the human androgen receptor with the amino-terminal domain and with the transcriptional coactivator TIF2 (transcriptional intermediary factor2)" 2247:. Regulation of signal transduction pathways by cytoplasmic androgen receptors can indirectly lead to changes in gene transcription, for example, by leading to phosphorylation of other transcription factors. 617: 516: 7945:
Nishimura K, Ting HJ, Harada Y, Tokizane T, Nonomura N, Kang HY, et al. (August 2003). "Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator".
7666:"Isolation and identification of L-dopa decarboxylase as a protein that binds to and enhances transcriptional activity of the androgen receptor using the repressed transactivator yeast two-hybrid system" 11010: 9318:"ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation" 2607: 10670:"The androgen receptor recruits nuclear receptor CoRepressor (N-CoR) in the presence of mifepristone via its N and C termini revealing a novel molecular mechanism for androgen receptor antagonists" 2101:
in the genes that code for AR. These mutations cause the inactivation of AR due to mutations conferring resistance to circulating testosterone, with more than 400 different AR mutations reported.
2028:
users of teen age may find that their growth had been stunted by androgen and/or estrogen excess. People with too little sex hormones can be short during puberty but end up taller as adults as in
2062:
Via the androgen receptor, androgens play a key role in the maintenance of male skeletal integrity. The regulation of this integrity by androgen receptor (AR) signaling can be attributed to both
6996:"Androgenic induction of prostate-specific antigen gene is repressed by protein-protein interaction between the androgen receptor and AP-1/c-Jun in the human prostate cancer cell line LNCaP" 4831:
Trapman J, Klaassen P, Kuiper GG, van der Korput JA, Faber PW, van Rooij HC, et al. (May 1988). "Cloning, structure and expression of a cDNA encoding the human androgen receptor".
2243:
proteins in the cytoplasm. Androgen binding to cytoplasmic androgen receptors can cause rapid changes in cell function independent of changes in gene transcription, such as changes in
6166:"Biomarker-Driven Therapy With Nivolumab and Ipilimumab in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer Expressing AR-V7 - Full Text View - ClinicalTrials.gov" 10357:"Convergence of two repressors through heterodimer formation of androgen receptor and testicular orphan receptor-4: a unique signaling pathway in the steroid receptor superfamily" 9444:"Regulation of androgen receptor signaling by PTEN (phosphatase and tensin homolog deleted on chromosome 10) tumor suppressor through distinct mechanisms in prostate cancer cells" 7307:
Ishitani K, Yoshida T, Kitagawa H, Ohta H, Nozawa S, Kato S (July 2003). "p54nrb acts as a transcriptional coactivator for activation function 1 of the human androgen receptor".
6908:
Park JJ, Irvine RA, Buchanan G, Koh SS, Park JM, Tilley WD, et al. (November 2000). "Breast cancer susceptibility gene 1 (BRCAI) is a coactivator of the androgen receptor".
11003: 10018:
Gobinet J, Auzou G, Nicolas JC, Sultan C, Jalaguier S (December 2001). "Characterization of the interaction between androgen receptor and a new transcriptional inhibitor, SHP".
8687:"Interaction of the putative androgen receptor-specific coactivator ARA70/ELE1alpha with multiple steroid receptors and identification of an internally deleted ELE1beta isoform" 16512: 18225: 7527:"From androgen receptor to the general transcription factor TFIIH. Identification of cdk activating kinase (CAK) as an androgen receptor NH(2)-terminal associated coactivator" 2600: 2972:, amplifications of the gene coding for this receptor or in its enhancer, mostly, suggesting the presence of different subclones with different genotypes of these receptors. 16766: 8846:"From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells" 18388: 11932: 9870:"Tip110, the human immunodeficiency virus type 1 (HIV-1) Tat-interacting protein of 110 kDa as a negative regulator of androgen receptor (AR) transcriptional activation" 16756: 16422: 10996: 1862: 7743:"EGF receptor (EGFR) signaling promoting invasion is disrupted in androgen-sensitive prostate cancer cells by an interaction between EGFR and androgen receptor (AR)" 7222:"The role of protein kinase A pathway and cAMP responsive element-binding protein in androgen receptor-mediated transcription at the prostate-specific antigen locus" 2593: 2089:
Moreover, the importance of understanding female androgen receptors lies in their role in several genetic disorders including androgen insensitivity syndrome (AIS).
17080: 6828:"Functional localization and competition between the androgen receptor and T-cell factor for nuclear beta-catenin: a means for inhibition of the Tcf signaling axis" 5207:
Herberts C, Annala M, Sipola J, Ng SW, Chen XE, Nurminen A, et al. (August 2022). "Deep whole-genome ctDNA chronology of treatment-resistant prostate cancer".
3484:
Quigley CA, De Bellis A, Marschke KB, el-Awady MK, Wilson EM, French FS (June 1995). "Androgen receptor defects: historical, clinical, and molecular perspectives".
12431: 5979:"Characterization of nuclear import of the domain-specific androgen receptor in association with the importin alpha/beta and Ran-guanosine 5'-triphosphate systems" 8135:
Nemoto T, Ohara-Nemoto Y, Ota M (September 1992). "Association of the 90-kDa heat shock protein does not affect the ligand-binding ability of androgen receptor".
8946:"RFG (ARA70, ELE1) interacts with the human androgen receptor in a ligand-dependent fashion, but functions only weakly as a coactivator in cotransfection assays" 8456:"Mechanistic relationship between androgen receptor polyglutamine tract truncation and androgen-dependent transcriptional hyperactivity in prostate cancer cells" 16454: 3127: 1998: 9110:"p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation" 5108:
Sartor O, Zheng Q, Eastham JA (February 1999). "Androgen receptor gene CAG repeat length varies in a race-specific fashion in men without prostate cancer".
4401:"p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation" 4028:"Androgen receptor (AR) in osteocytes is important for the maintenance of male skeletal integrity: evidence from targeted AR disruption in mouse osteocytes" 1964:; however, the androgen receptor has other functions as well. Androgen-regulated genes are critical for the development and maintenance of the male sexual 7498:
Knudsen KE, Cavenee WK, Arden KC (May 1999). "D-type cyclins complex with the androgen receptor and inhibit its transcriptional transactivation ability".
4442:"Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function" 1470: 14638: 1451: 18202: 10863: 9950:
Hayes SA, Zarnegar M, Sharma M, Yang F, Peehl DM, ten Dijke P, et al. (March 2001). "SMAD3 represses androgen receptor-mediated transcription".
2042:
studies have shown that the androgen receptor is essential for normal female fertility, being required for development and full functionality of the
439: 16886: 13316: 12338: 12333: 12328: 5893:
Callewaert L, Van Tilborgh N, Claessens F (January 2006). "Interplay between two hormone-independent activation domains in the androgen receptor".
11977: 8363:"Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells" 5358:
Brinkmann AO, Klaasen P, Kuiper GG, van der Korput JA, Bolt J, de Boer W, et al. (1989). "Structure and function of the androgen receptor".
4972:
Kennedy WR, Alter M, Sung JH (July 1968). "Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex-linked recessive trait".
6869:"Liganded androgen receptor interaction with beta-catenin: nuclear co-localization and modulation of transcriptional activity in neuronal cells" 17774: 17764: 11962: 11648: 1787:
crystal structure of the human androgen receptor ligand binding domain bound with an androgen receptor nh2-terminal peptide, ar20-30, and r1881
7857:"AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR" 18207: 4731:"Testosterone activates mitogen-activated protein kinase and the cAMP response element binding protein transcription factor in Sertoli cells" 3466: 18248: 18243: 18028: 17804: 17794: 12471: 7401:
Reutens AT, Watanabe G, Albanese C, McPhaul MJ, Balk SP, Pestell RG (1998). "Cyclin D1 binds activating mutants of the androgen receptor".
3448: 2172:
One function of androgen receptor that is independent of direct binding to its target DNA sequence is facilitated by recruitment via other
9485:"Human checkpoint protein hRad9 functions as a negative coregulator to repress androgen receptor transactivation in prostate cancer cells" 7418:"Cyclin D1 binds the androgen receptor and regulates hormone-dependent signaling in a p300/CBP-associated factor (P/CAF)-dependent manner" 18547: 18482: 18477: 18427: 18258: 18172: 17784: 16266: 16250: 11069: 10908:
GeneReviews/NIH/NCBI/UW entry on Spinal and Bulbar Muscular Atrophy, Kennedy's Disease, SBMA, X-Linked Spinal and Bulbar Muscular Atrophy
10312:
Mu X, Chang C (October 2003). "TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC-3".
9829:"Coregulator small nuclear RING finger protein (SNURF) enhances Sp1- and steroid receptor-mediated transcription by different mechanisms" 6705:"Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells" 54: 8232:"Epidermal-growth-factor-dependent phosphorylation and ubiquitinylation of MAGE-11 regulates its interaction with the androgen receptor" 18542: 18417: 18368: 18192: 18177: 18108: 17819: 17729: 16447: 12323: 9534:"RanBPM, a nuclear protein that interacts with and regulates transcriptional activity of androgen receptor and glucocorticoid receptor" 3386: 18701: 18008: 18003: 17993: 17834: 17664: 15039: 15034: 15029: 15024: 15019: 12108: 12101: 12096: 12084: 12079: 12074: 12069: 12064: 11992: 7975:"The scaffolding protein RACK1 interacts with androgen receptor and promotes cross-talk through a protein kinase C signaling pathway" 7906:"Spinocerebellar ataxia type-1 and spinobulbar muscular atrophy gene products interact with glyceraldehyde-3-phosphate dehydrogenase" 5845:
Van-Duyne G, Blair IA, Sprenger C, Moiseenkova-Bell V, Plymate S, Penning TM (2023-01-01). Litwack G (ed.). "The androgen receptor".
4540:"Activation of p300 histone acetyltransferase activity and acetylation of the androgen receptor by bombesin in prostate cancer cells" 3923: 3289: 1714: 8987:"Interactions between activating signal cointegrator-2 and the tumor suppressor retinoblastoma in androgen receptor transactivation" 8016:"Suppression of androgen receptor-mediated transactivation and cell growth by the glycogen synthase kinase 3 beta in prostate cells" 3519:
Gottlieb B, Lombroso R, Beitel LK, Trifiro MA (January 2005). "Molecular pathology of the androgen receptor in male (in)fertility".
2239:, androgen receptors can have actions that are independent of their interactions with DNA. Androgen receptors interact with certain 1721: 18537: 18358: 17709: 15988: 14111: 10928: 10457:"Isolation and characterization of ARA160 as the first androgen receptor N-terminal-associated coactivator in human prostate cells" 3097: 2090: 8787:"Promotion of agonist activity of antiandrogens by the androgen receptor coactivator, ARA70, in human prostate cancer DU145 cells" 7137:"Androgen receptor interacts with the positive elongation factor P-TEFb and enhances the efficiency of transcriptional elongation" 18706: 17186: 15199: 15194: 15144: 15134: 15114: 15099: 15079: 15004: 14984: 14126: 14121: 12787: 2094: 4788:
Chang CS, Kokontis J, Liao ST (April 1988). "Molecular cloning of human and rat complementary DNA encoding androgen receptors".
2315:
white Americans. The racial trends in CAG repeats parallels the incidence and mortality of prostate cancer in these two groups.
2082:
female mice, provides evidence that the promotion of cardiac growth, kidney hypertrophy, cortical bone growth and regulation of
17699: 14355: 14313: 14308: 14303: 14241: 14075: 13863: 13814: 13809: 11856: 11846: 8060:"Tip60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor" 9739:"Cloning and characterization of human prostate coactivator ARA54, a novel protein that associates with the androgen receptor" 9698:"A dominant-negative mutant of androgen receptor coregulator ARA54 inhibits androgen receptor-mediated prostate cancer growth" 1981:
In some cell types, testosterone interacts directly with androgen receptors, whereas, in others, testosterone is converted by
18696: 17648: 16440: 5866: 5017:"Androgen-dependent pathology demonstrates myopathic contribution to the Kennedy disease phenotype in a mouse knock-in model" 3697: 2819: 2166: 16781: 9575:"Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity" 3431: 1882: 18727: 18691: 16687: 4278:"Androgen receptor (AR) coregulators: a diversity of functions converging on and regulating the AR transcriptional complex" 3223: 10813: 6069:"Novel Insights into Molecular Indicators of Response and Resistance to Modern Androgen-Axis Therapies in Prostate Cancer" 3987:"Molecular insights into androgen actions in male and female reproductive function from androgen receptor knockout models" 2169:(IGF-1R). Thus, changes in levels of specific proteins in cells is one way that androgen receptors control cell behavior. 17036: 15751: 11643: 11215: 4868:"Refinement of evolutionary medicine predictions based on clinical evidence for the manifestations of Mendelian diseases" 3721:
Bardin CW, Brown T, Isomaa VV, Jänne OA (1983). "Progestins can mimic, inhibit and potentiate the actions of androgens".
3410: 10934: 10913:
OMIM entries on Spinal and Bulbar Muscular Atrophy, Kennedy's Disease, SBMA, X-Linked Spinal and Bulbar Muscular Atrophy
10214:"Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathways" 10055:"Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence" 2440:) nd 370–494, both of which interact with the ligand binding domain (LBD) in an intramolecular head-to-tail interaction 2414:
Like other nuclear receptors, the androgen receptor is modular in structure and is composed of the following functional
17443: 17438: 16020: 14919: 13006: 10416:"Suppression of androgen receptor transactivation by Pyk2 via interaction and phosphorylation of the ARA55 coregulator" 7568:"The cell fate determination factor dachshund inhibits androgen receptor signaling and prostate cancer cellular growth" 6521:"The cochaperone Bag-1L enhances androgen receptor action via interaction with the NH2-terminal region of the receptor" 16876: 8183:"Melanoma antigen gene protein MAGE-11 regulates androgen receptor function by modulating the interdomain interaction" 2497:) – Hinge region; flexible region that connects the DBD with the LBD; along with the DBD, contains a ligand dependent 17105: 16682: 12464: 12459: 12387: 12377: 11254: 11244: 11079: 9657:"Retinoblastoma, a tumor suppressor, is a coactivator for the androgen receptor in human prostate cancer DU145 cells" 2208: 1989:
for androgen receptor activation. Testosterone appears to be the primary androgen receptor-activating hormone in the
17888: 5554:"The structural basis of androgen receptor activation: intramolecular and intermolecular amino-carboxy interactions" 2231:
More recently, androgen receptors have been shown to have a second mode of action. As has been also found for other
603: 18287: 17192: 17155: 16985: 16950: 12382: 12296: 5145:"The effect of CAG repeats length on differences in hirsutism among healthy Israeli women of different ethnicities" 3085: 2570:
High expression in androgen receptor has been linked to aggression and sex drive by affecting the HPA and HPG axis
16881: 8728:"Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells" 2509:
activation function 2 (AF-2), responsible for agonist induced activity (activity in the presence of bound agonist)
17110: 15318: 12594: 12584: 11185: 11064: 7096:"Caveolin-1 interacts with androgen receptor. A positive modulator of androgen receptor mediated transactivation" 6937:"Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells" 3435: 3414: 3187: 2280: 2184: 2033: 2029: 580: 9780:"Identification of a novel RING finger protein as a coregulator in steroid receptor-mediated gene transcription" 7742: 16640: 12949: 12589: 12284: 3169: 3163: 3157: 2892: 2296: 2078:
The AR plays a role in regulating female sexual, somatic, and behavioral functions. Experimental data using AR
1515: 17878: 5452:"Identification of two transcription activation units in the N-terminal domain of the human androgen receptor" 2964:
Alteration of ARs may lead to treatment resistance (castration resistance) in prostate cancer as there may be
1870: 16231: 16226: 15377: 12289: 6659:"Antiandrogen effects of mifepristone on coactivator and corepressor interactions with the androgen receptor" 16547: 16527: 10907: 5804:
Dubbink HJ, Hersmus R, Verma CS, van der Korput HA, Berrevoets CA, van Tol J, et al. (September 2004).
1496: 18686: 18656: 18221: 17515: 16903: 16326: 14662: 12812: 12365: 12355: 9979:"Differential modulation of androgen receptor-mediated transactivation by Smad3 and tumor suppressor Smad4" 2010: 502: 477: 419: 17376: 16729: 16542: 10872: 10847: 9911:"The androgen receptor represses transforming growth factor-beta signaling through interaction with Smad3" 4360:"Recruitment of the androgen receptor via serum response factor facilitates expression of a myogenic gene" 2283:, formerly known as testicular feminization, is caused by a mutation in the androgen receptor gene on the 17593: 16955: 16557: 14831: 14826: 14377: 12454: 12372: 12360: 11436: 10711:"Identification and characterization of ART-27, a novel coactivator for the androgen receptor N terminus" 2981: 2498: 17578: 17573: 17381: 5403:"Dynamic phase separation of the androgen receptor and its coactivators key to regulate gene expression" 4491:"Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth" 18732: 17115: 16734: 12567: 11565: 3381: 3067: 1961: 1866: 17883: 8685:
Alen P, Claessens F, Schoenmakers E, Swinnen JV, Verhoeven G, Rombauts W, et al. (January 1999).
6028:"Identification and characterization of a ligand-regulated nuclear export signal in androgen receptor" 2016:
Androgens cause slow maturation of the bones, but more of the potent maturation effect comes from the
16945: 16672: 16618: 15983: 12864: 12849: 12832: 12827: 12822: 12817: 12728: 12703: 12579: 12491: 12481: 11638: 11111: 7457:
Petre-Draviam CE, Williams EB, Burd CJ, Gladden A, Moghadam H, Meller J, et al. (January 2005).
6570:"Structure-function analysis of Bag1 proteins. Effects on androgen receptor transcriptional activity" 3295: 3055: 2862: 2623: 2574: 2232: 1676: 616: 515: 16724: 10988: 9359:"A testis-specific androgen receptor coregulator that belongs to a novel family of nuclear proteins" 17535: 17504: 17224: 17165: 16898: 16676: 16552: 16502: 15725: 15360: 14876: 14449: 14288: 13223: 13218: 13203: 12678: 12653: 12535: 12486: 12279: 11670: 11136: 10921: 10629:"Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor" 9573:
Beitel LK, Elhaji YA, Lumbroso R, Wing SS, Panet-Raymond V, Gottlieb B, et al. (August 2002).
7263:"CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1" 7037:"Physical and functional interaction of androgen receptor with calmodulin in prostate cancer cells" 6367:
Helsen C, Van den Broeck T, Voet A, Prekovic S, Van Poppel H, Joniau S, et al. (August 2014).
6320:"Molecules targeting the androgen receptor (AR) signaling axis beyond the AR-Ligand binding domain" 4358:
Vlahopoulos S, Zimmer WE, Jenster G, Belaguli NS, Balk SP, Brinkmann AO, et al. (March 2005).
2165:
to produce specific proteins. One of the known target genes of androgen receptor activation is the
2150: 2146: 1662: 1658: 1654: 1650: 1605: 1601: 1597: 1589: 609: 508: 427: 406: 17873: 17608: 17588: 10760:"hZimp10 is an androgen receptor co-activator and forms a complex with SUMO-1 at replication foci" 5552:
Schaufele F, Carbonell X, Guerbadot M, Borngraeber S, Chapman MS, Ma AA, et al. (July 2005).
5143:
Weintrob N, Eyal O, Slakman M, Segev Becker A, Israeli G, Kalter-Leibovici O, et al. (2018).
1672: 18404: 17331: 16893: 16793: 16090: 14131: 13448: 12562: 12550: 8281:"A coregulatory role for the TRAP-mediator complex in androgen receptor-mediated gene expression" 7035:
Cifuentes E, Mataraza JM, Yoshida BA, Menon M, Sacks DB, Barrack ER, et al. (January 2004).
5711:"Evidence for an anti-parallel orientation of the ligand-activated human androgen receptor dimer" 5501:
Asangani I, Blair IA, Van Duyne G, Hilser VJ, Moiseenkova-Bell V, Plymate S, et al. (2021).
17075: 10912: 10902: 9909:
Chipuk JE, Cornelius SC, Pultz NJ, Jorgensen JS, Bonham MJ, Kim SJ, et al. (January 2002).
7741:
Bonaccorsi L, Carloni V, Muratori M, Formigli L, Zecchi S, Forti G, et al. (October 2004).
5503:"Using biochemistry and biophysics to extinguish androgen receptor signaling in prostate cancer" 4026:
Sinnesael M, Claessens F, Laurent M, Dubois V, Boonen S, Deboel L, et al. (December 2012).
2287:(locus: Xq11–Xq12). The androgen receptor seems to affect neuron physiology and is defective in 1697: 1646: 1626: 1593: 18396: 17531: 17170: 17041: 16913: 16761: 16630: 16579: 16221: 14268: 14263: 12658: 12555: 12350: 12311: 11374: 11023: 10498:"TRIM68 regulates ligand-dependent transcription of androgen receptor in prostate cancer cells" 7904:
Koshy B, Matilla T, Burright EN, Merry DE, Fischbeck KH, Orr HT, et al. (September 1996).
6462:"Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor" 3259: 2840: 2773: 2555: 2517: 1894: 17868: 10917: 3839:"The roles of androgen receptors and androgen-binding proteins in nongenomic androgen actions" 2157:
transcription. Up-regulation or activation of transcription results in increased synthesis of
17928: 17416: 17266: 17160: 16825: 16507: 16213: 15773: 12572: 12508: 12503: 12316: 11392: 10496:
Miyajima N, Maruyama S, Bohgaki M, Kano S, Shigemura M, Shinohara N, et al. (May 2008).
9069:"The amino terminus of the human AR is target for corepressor action and antihormone agonism" 6787:"A direct beta-catenin-independent interaction between androgen receptor and T cell factor 4" 5660:
van Royen ME, Cunha SM, Brink MC, Mattern KA, Nigg AL, Dubbink HJ, et al. (April 2007).
5611:
Klokk TI, Kurys P, Elbi C, Nagaich AK, Hendarwanto A, Slagsvold T, et al. (March 2007).
3331: 3325: 2969: 2925: 2848: 2524: 2471: 2460: 2177: 2130: 1943: 10668:
Hodgson MC, Astapova I, Cheng S, Lee LJ, Verhoeven MC, Choi E, et al. (February 2005).
9616:"Differential regulation of androgen and glucocorticoid receptors by retinoblastoma protein" 9357:
Moilanen AM, Karvonen U, Poukka H, Yan W, Toppari J, Jänne OA, et al. (February 1999).
9277:"PATZ attenuates the RNF4-mediated enhancement of androgen receptor-dependent transcription" 9151:"Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1" 6703:
Masiello D, Chen SY, Xu Y, Verhoeven MC, Choi E, Hollenberg AN, et al. (October 2004).
6116:
Antonarakis ES, Lu C, Wang H, Luber B, Nakazawa M, Roeser JC, et al. (September 2014).
4581:"The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity" 3950:
Frank GR (September 2003). "Role of estrogen and androgen in pubertal skeletal physiology".
18088: 17556: 17527: 17500: 17366: 17254: 17063: 17031: 16997: 16635: 16606: 15794: 15786: 13624: 13106: 12631: 12626: 12621: 12301: 12184: 11019: 10578:
Müller JM, Isele U, Metzger E, Rempel A, Moser M, Pscherer A, et al. (February 2000).
10368: 10266: 10096:"Mechanisms of androgen receptor signalling via steroid receptor coactivator-1 in prostate" 9108:
Fu M, Wang C, Reutens AT, Wang J, Angeletti RH, Siconolfi-Baez L, et al. (July 2000).
8857: 8798: 8739: 7355: 7048: 6948: 6473: 5613:"Ligand-specific dynamics of the androgen receptor at its response element in living cells" 5565: 5271: 5216: 5156: 4879: 4797: 4742: 4685: 4399:
Fu M, Wang C, Reutens AT, Wang J, Angeletti RH, Siconolfi-Baez L, et al. (July 2000).
4317:
Pandini G, Mineo R, Frasca F, Roberts CT, Marcelli M, Vigneri R, et al. (March 2005).
3043: 2513: 2288: 2115: 1957: 1849: 1366:
positive regulation of epithelial cell proliferation involved in prostate gland development
491: 16719: 10539:"Ubc9 interacts with the androgen receptor and activates receptor-dependent transcription" 10255:"Supervillin associates with androgen receptor and modulates its transcriptional activity" 9275:
Pero R, Lembo F, Palmieri EA, Vitiello C, Fedele M, Fusco A, et al. (February 2002).
6994:
Sato N, Sadar MD, Bruchovsky N, Saatcioglu F, Rennie PS, Sato S, et al. (July 1997).
6519:
Shatkina L, Mink S, Rogatsch H, Klocker H, Langer G, Nestl A, et al. (October 2003).
4319:"Androgens up-regulate the insulin-like growth factor-I receptor in prostate cancer cells" 8: 18611: 18606: 18338: 18298: 18143: 18063: 17963: 17953: 17898: 17478: 17014: 16771: 16625: 16522: 16108: 15812: 15508: 13711: 12916: 12498: 12476: 12449: 12411: 12345: 10940: 9696:
Miyamoto H, Rahman M, Takatera H, Kang HY, Yeh S, Chang HC, et al. (February 2002).
8404:"The AF1 and AF2 domains of the androgen receptor interact with distinct regions of SRC1" 3799:
Mooradian AD, Morley JE, Korenman SG (February 1987). "Biological actions of androgens".
2945: 2844: 2761: 2655: 2324: 2240: 2220: 2216: 2173: 1954: 1931: 10372: 10270: 10137:"SRY interacts with and negatively regulates androgen receptor transcriptional activity" 8861: 8802: 8743: 7359: 7052: 6952: 6477: 5662:"Compartmentalization of androgen receptor protein-protein interactions in living cells" 5569: 5401:
Zhang F, Biswas M, Massah S, Lee J, Lingadahalli S, Wong S, et al. (January 2023).
5275: 5220: 5160: 5015:
Yu Z, Dadgar N, Albertelli M, Gruis K, Jordan C, Robins DM, et al. (October 2006).
4883: 4801: 4746: 4689: 4538:
Gong J, Zhu J, Goodman OB, Pestell RG, Schlegel PN, Nanus DM, et al. (March 2006).
4253: 4228: 447: 17448: 17311: 17271: 17249: 17182: 17085: 17058: 17026: 16859: 16749: 16601: 16466: 15646: 10871:(Ph.D. thesis). University of Helsinki. Biomedical Dissertations No. 80. Archived from 10758:
Sharma M, Li X, Wang Y, Zarnegar M, Huang CY, Palvimo JJ, et al. (November 2003).
10709:
Markus SM, Taneja SS, Logan SK, Li W, Ha S, Hittelman AB, et al. (February 2002).
10337: 8616: 8591: 8256: 8231: 8160: 7837: 7783: 7690: 7665: 7632: 7592: 7567: 7202: 6434: 6409: 6344: 6319: 6215: 6190: 6142: 6117: 6093: 6068: 6003: 5978: 5954: 5929: 5686: 5661: 5637: 5612: 5588: 5553: 5529: 5502: 5427: 5402: 5383: 5240: 5179: 5144: 5041: 5016: 4997: 4954: 4941: 4924: 4900: 4867: 4706: 4673: 4649: 4624: 4209: 4160: 3903: 3781: 3662: 2965: 2953: 2786: 2779: 2483: 2433:) – N-terminal is a regulatory domain which is intrinsically disordered that contains: 2134: 2119: 451: 10784: 10759: 10604: 10579: 10289: 10254: 10094:
Powell SM, Christiaens V, Voulgaraki D, Waxman J, Claessens F, Bevan CL (March 2004).
9804: 9779: 9509: 9484: 9026:
Liao G, Chen LY, Zhang A, Godavarthy A, Xia F, Ghosh JC, et al. (February 2003).
8526: 8501: 8207: 8182: 7881: 7856: 7641: 7616: 7320: 7190: 7071: 7036: 6867:
Pawlowski JE, Ertel JR, Allen MP, Xu M, Butler C, Wilson EM, et al. (June 2002).
6545: 6520: 5260:"A and B forms of the androgen receptor are present in human genital skin fibroblasts" 5121: 4844: 4765: 4730: 4515: 4490: 4466: 4441: 3689: 3532: 1385: 1380: 1375: 1370: 1365: 1360: 1355: 1350: 1345: 1340: 1335: 1330: 1325: 1320: 1315: 1310: 1305: 1300: 1295: 1290: 1285: 1280: 1275: 1270: 1265: 1260: 1255: 1250: 1245: 1240: 1235: 1230: 1225: 1220: 1215: 1210: 1205: 1200: 1195: 1190: 1185: 1180: 1175: 1170: 1165: 1160: 1155: 1150: 1145: 1140: 1135: 1130: 1125: 1120: 1115: 1110: 1105: 1100: 1095: 1090: 1085: 1080: 1075: 1059: 1054: 1049: 1044: 1039: 1034: 1029: 1013: 1008: 1003: 998: 993: 988: 983: 978: 973: 968: 963: 958: 953: 948: 943: 938: 933: 928: 923: 918: 913: 908: 903: 18462: 18078: 18038: 17903: 17679: 17598: 17401: 17306: 17125: 16842: 16704: 16613: 16596: 16564: 16517: 15228: 15219: 14856: 13804: 12545: 10977: 10968: 10956: 10947: 10789: 10740: 10735: 10710: 10691: 10650: 10609: 10560: 10519: 10478: 10437: 10396: 10391: 10356: 10329: 10294: 10235: 10194: 10158: 10117: 10076: 10053:
Unni E, Sun S, Nan B, McPhaul MJ, Cheskis B, Mancini MA, et al. (October 2004).
10035: 10000: 9959: 9932: 9891: 9850: 9809: 9760: 9719: 9678: 9637: 9596: 9555: 9514: 9465: 9421: 9380: 9339: 9298: 9254: 9213: 9172: 9131: 9090: 9049: 9008: 8967: 8926: 8885: 8880: 8845: 8826: 8821: 8786: 8767: 8762: 8727: 8708: 8667: 8621: 8572: 8531: 8477: 8433: 8428: 8403: 8384: 8343: 8302: 8261: 8212: 8152: 8148: 8117: 8081: 8037: 7996: 7955: 7927: 7886: 7829: 7775: 7723: 7695: 7646: 7597: 7548: 7507: 7480: 7439: 7383: 7378: 7343: 7324: 7284: 7243: 7194: 7158: 7117: 7076: 7017: 6976: 6971: 6936: 6917: 6890: 6849: 6808: 6767: 6726: 6680: 6632: 6591: 6550: 6536: 6501: 6496: 6461: 6439: 6390: 6349: 6297: 6293: 6261: 6220: 6147: 6098: 6049: 6008: 5959: 5910: 5872: 5862: 5827: 5783: 5732: 5691: 5642: 5593: 5534: 5483: 5432: 5375: 5340: 5299: 5294: 5259: 5244: 5232: 5184: 5125: 5087: 5082: 5065: 5046: 4989: 4946: 4905: 4848: 4813: 4770: 4711: 4674:"lncRNA-dependent mechanisms of androgen-receptor-regulated gene activation programs" 4654: 4602: 4561: 4520: 4506: 4471: 4457: 4422: 4381: 4340: 4299: 4258: 4201: 4164: 4119: 4084: 4049: 4008: 3967: 3932: 3907: 3895: 3860: 3816: 3773: 3769: 3738: 3734: 3703: 3693: 3654: 3618: 3577: 3556:"Trinucleotide repeats in the human androgen receptor: a molecular basis for disease" 3536: 3501: 2949: 2415: 2299: 2236: 1982: 1857: 399: 47: 10341: 9655:
Yeh S, Miyamoto H, Nishimura K, Kang H, Ludlow J, Hsiao P, et al. (July 1998).
9500: 8646:"The FXXLF motif mediates androgen receptor-specific interactions with coregulators" 8517: 8502:"Electrostatic modulation in steroid receptor recruitment of LXXLL and FXXLF motifs" 8198: 8164: 7841: 7787: 7206: 6026:
Saporita AJ, Zhang Q, Navai N, Dincer Z, Hahn J, Cai X, et al. (October 2003).
5387: 5001: 4958: 4213: 4115: 3785: 3666: 1811: 18348: 18328: 17276: 17140: 16699: 16537: 16497: 13755: 13737: 12306: 12253: 12027: 10779: 10771: 10730: 10722: 10681: 10640: 10599: 10591: 10550: 10509: 10468: 10427: 10386: 10376: 10321: 10284: 10274: 10225: 10186: 10148: 10107: 10066: 10027: 9990: 9922: 9881: 9840: 9799: 9791: 9778:
Moilanen AM, Poukka H, Karvonen U, Häkli M, Jänne OA, Palvimo JJ (September 1998).
9750: 9709: 9668: 9627: 9586: 9545: 9504: 9496: 9455: 9411: 9370: 9329: 9288: 9244: 9231:
Lee SR, Ramos SM, Ko A, Masiello D, Swanson KD, Lu ML, et al. (January 2002).
9203: 9162: 9121: 9080: 9067:
Dotzlaw H, Moehren U, Mink S, Cato AC, Iñiguez Lluhí JA, Baniahmad A (April 2002).
9039: 9028:"Regulation of androgen receptor activity by the nuclear receptor corepressor SMRT" 8998: 8957: 8916: 8875: 8865: 8816: 8806: 8757: 8747: 8698: 8657: 8611: 8603: 8562: 8521: 8513: 8467: 8423: 8415: 8374: 8333: 8292: 8251: 8243: 8202: 8194: 8144: 8109: 8071: 8027: 7986: 7917: 7876: 7868: 7819: 7815: 7811: 7765: 7757: 7685: 7677: 7636: 7628: 7587: 7579: 7538: 7470: 7429: 7373: 7363: 7316: 7274: 7233: 7186: 7148: 7107: 7066: 7056: 7007: 6966: 6956: 6880: 6839: 6798: 6757: 6716: 6670: 6622: 6581: 6540: 6532: 6491: 6481: 6429: 6421: 6380: 6339: 6331: 6289: 6251: 6210: 6202: 6137: 6129: 6088: 6080: 6039: 5998: 5990: 5949: 5941: 5902: 5854: 5817: 5773: 5763: 5722: 5681: 5673: 5632: 5624: 5583: 5573: 5524: 5514: 5473: 5463: 5422: 5414: 5367: 5330: 5289: 5279: 5224: 5174: 5164: 5117: 5077: 5036: 5028: 4981: 4936: 4895: 4887: 4840: 4805: 4760: 4750: 4701: 4693: 4644: 4636: 4592: 4551: 4510: 4502: 4461: 4453: 4412: 4371: 4330: 4289: 4248: 4240: 4191: 4150: 4111: 4076: 4039: 3998: 3959: 3887: 3850: 3808: 3765: 3730: 3685: 3646: 3608: 3567: 3528: 3493: 2685: 2381: 2043: 1994: 1916: 1845: 696: 627: 571: 526: 17613: 10514: 10497: 10071: 10054: 9398:
Zhao Y, Goto K, Saitoh M, Yanase T, Nomura M, Okabe T, et al. (August 2002).
9192:"Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6" 8551:"Thyroid receptor activator molecule, TRAM-1, is an androgen receptor coactivator" 7872: 7583: 6165: 5906: 4489:
Fu M, Rao M, Wang C, Sakamaki T, Wang J, Di Vizio D, et al. (December 2003).
4335: 4318: 2086:
bone structure is a result of DNA-binding-dependent actions of the AR in females.
431: 18273: 18158: 18013: 17684: 17351: 17326: 17177: 17130: 16940: 16800: 15896: 15119: 14989: 14153: 8592:"Expression of RAC 3, a steroid hormone receptor co-activator in prostate cancer" 7664:
Wafa LA, Cheng H, Rao MA, Nelson CC, Cox M, Hirst M, et al. (October 2003).
7615:
Lin DY, Fang HI, Ma AH, Huang YS, Pu YS, Jenster G, et al. (December 2004).
7566:
Wu K, Katiyar S, Witkiewicz A, Li A, McCue P, Song LN, et al. (April 2009).
7416:
Reutens AT, Fu M, Wang C, Albanese C, McPhaul MJ, Sun Z, et al. (May 2001).
5169: 3921:
Sinisi AA, Pasquali D, Notaro A, Bellastella A (2003). "Sexual differentiation".
2917: 2765: 2578: 2559: 2362: 2200: 2192: 1823: 671: 455: 8905:"Domain interactions between coregulator ARA(70) and the androgen receptor (AR)" 4229:"Compartmentalization of androgen receptors at endogenous genes in living cells" 3471:
National Center for Biotechnology Information, U.S. National Library of Medicine
3453:
National Center for Biotechnology Information, U.S. National Library of Medicine
18118: 17943: 17918: 17546: 17522: 17495: 17391: 17316: 17219: 17004: 16975: 16832: 16775: 16714: 16709: 16432: 15993: 14273: 14256: 12399: 12054: 11051: 10824: 10361:
Proceedings of the National Academy of Sciences of the United States of America
10259:
Proceedings of the National Academy of Sciences of the United States of America
9532:
Rao MA, Cheng H, Quayle AN, Nishitani H, Nelson CC, Rennie PS (December 2002).
9149:
Zhang Y, Fondell JD, Wang Q, Xia X, Cheng A, Lu ML, et al. (August 2002).
8850:
Proceedings of the National Academy of Sciences of the United States of America
8791:
Proceedings of the National Academy of Sciences of the United States of America
8732:
Proceedings of the National Academy of Sciences of the United States of America
7348:
Proceedings of the National Academy of Sciences of the United States of America
7041:
Proceedings of the National Academy of Sciences of the United States of America
6941:
Proceedings of the National Academy of Sciences of the United States of America
6466:
Proceedings of the National Academy of Sciences of the United States of America
5806:"Distinct recognition modes of FXXLF and LXXLL motifs by the androgen receptor" 5558:
Proceedings of the National Academy of Sciences of the United States of America
5264:
Proceedings of the National Academy of Sciences of the United States of America
5228: 4891: 4735:
Proceedings of the National Academy of Sciences of the United States of America
2852: 2769: 2645: 2551: 2292: 2212: 2079: 2051: 772: 410:, AIS, AR8, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM, androgen receptor 17458: 10897: 7459:"A central domain of cyclin D1 mediates nuclear receptor corepressor activity" 6744:
Yang F, Li X, Sharma M, Sasaki CY, Longo DL, Lim B, et al. (March 2002).
6084: 5858: 5750:
Berrevoets CA, Doesburg P, Steketee K, Trapman J, Brinkmann AO (August 1998).
5519: 2459:
Transactivation unit 1 (TAU-1) between residues 101 and 370 required for full
2332:), make the disease progression determined by the androgen receptor genotype. 2279:
At least 165 disease-causing mutations in this gene have been discovered. The
2203:
cells. AR acetylation is induced by androgens and determines recruitment into
2005:. Testosterone is therefore responsible primarily for the development of male 18721: 18527: 18472: 18447: 18023: 17421: 17321: 16532: 14851: 14191: 12616: 12404: 11732: 10595: 10555: 10538: 10473: 10456: 10381: 9632: 9615: 9316:
Kotaja N, Aittomäki S, Silvennoinen O, Palvimo JJ, Jänne OA (December 2000).
8985:
Goo YH, Na SY, Zhang H, Xu J, Hong S, Cheong J, et al. (February 2004).
8590:
Gnanapragasam VJ, Leung HY, Pulimood AS, Neal DE, Robson CN (December 2001).
7279: 7262: 7012: 6995: 6935:
Yeh S, Hu YC, Rahman M, Lin HK, Hsu CL, Ting HJ, et al. (October 2000).
6627: 6610: 5727: 5710: 4440:
Fu M, Wang C, Wang J, Zhang X, Sakamaki T, Yeung YG, et al. (May 2002).
2444: 2340: 2158: 2149:. The androgen receptor dimer binds to a specific sequence of DNA known as a 2039: 2021: 2002: 1990: 890: 10414:
Wang X, Yang Y, Guo X, Sampson ER, Hsu CL, Tsai MY, et al. (May 2002).
9755: 9738: 9334: 9317: 8962: 8945: 8870: 8811: 8752: 8567: 8550: 7543: 7526: 7061: 5578: 5468: 5451: 4809: 4755: 4155: 4138: 4080: 4003: 3986: 3680:
Roy AK, Lavrovsky Y, Song CS, Chen S, Jung MH, Velu NK, et al. (1999).
1191:
positive regulation of insulin-like growth factor receptor signaling pathway
832: 710: 18666: 18522: 18452: 18353: 18343: 18308: 18278: 18212: 18187: 18138: 18093: 18058: 18033: 17978: 17933: 17769: 17551: 17468: 17356: 17286: 17261: 17209: 17199: 17145: 16992: 16925: 16810: 16805: 16788: 16739: 16401: 15713: 15596: 15588: 14959: 14915: 13918: 13766: 10793: 10775: 10744: 10726: 10695: 10686: 10669: 10654: 10645: 10628: 10613: 10564: 10523: 10482: 10441: 10432: 10415: 10400: 10333: 10298: 10279: 10239: 10230: 10213: 10198: 10190: 10162: 10153: 10136: 10121: 10080: 10039: 10004: 9995: 9978: 9963: 9936: 9927: 9910: 9895: 9886: 9869: 9854: 9764: 9723: 9714: 9697: 9673: 9656: 9600: 9559: 9550: 9533: 9518: 9469: 9425: 9416: 9399: 9375: 9358: 9343: 9302: 9293: 9276: 9258: 9249: 9232: 9217: 9208: 9191: 9176: 9167: 9150: 9135: 9126: 9109: 9094: 9085: 9068: 9053: 9044: 9027: 9012: 9003: 8986: 8971: 8930: 8921: 8904: 8889: 8703: 8686: 8671: 8662: 8645: 8625: 8607: 8576: 8535: 8481: 8472: 8455: 8437: 8419: 8388: 8379: 8362: 8347: 8338: 8321: 8306: 8297: 8280: 8265: 8216: 8085: 8076: 8059: 8041: 8032: 8015: 8000: 7991: 7974: 7959: 7922: 7905: 7890: 7833: 7779: 7727: 7699: 7650: 7617:"Negative modulation of androgen receptor transcriptional activity by Daxx" 7601: 7552: 7511: 7484: 7475: 7458: 7443: 7434: 7417: 7368: 7328: 7247: 7198: 7162: 7153: 7136: 7121: 7112: 7095: 7080: 6980: 6961: 6921: 6894: 6885: 6868: 6853: 6844: 6827: 6812: 6803: 6786: 6771: 6762: 6745: 6730: 6684: 6595: 6586: 6569: 6554: 6505: 6486: 6443: 6394: 6353: 6265: 6256: 6239: 6224: 6151: 6102: 6053: 6044: 6027: 6012: 5963: 5914: 5876: 5831: 5768: 5751: 5695: 5646: 5597: 5538: 5436: 5418: 5344: 5284: 5236: 5188: 5091: 5050: 4909: 4774: 4715: 4658: 4623:
Fu M, Liu M, Sauve AA, Jiao X, Zhang X, Wu X, et al. (November 2006).
4606: 4597: 4580: 4565: 4556: 4539: 4524: 4475: 4426: 4417: 4400: 4385: 4376: 4359: 4344: 4303: 4262: 4205: 4123: 4088: 4053: 4012: 3971: 3936: 3899: 3864: 3777: 3658: 3622: 3540: 3019: 3001: 2937: 2921: 2878: 2874: 2790: 2757: 2665: 2329: 2284: 2268: 2142: 1939: 1927: 689: 468: 10112: 10095: 9845: 9828: 9813: 9795: 9682: 9641: 9591: 9574: 9384: 8830: 8771: 8712: 8156: 8121: 7931: 7387: 7288: 7021: 6636: 6301: 6133: 5930:"Androgen receptor: structure, role in prostate cancer and drug discovery" 5787: 5736: 5677: 5487: 5379: 5335: 5318: 5303: 5129: 4993: 4950: 4852: 4817: 4672:
Yang L, Lin C, Jin C, Yang JC, Tanasa B, Li W, et al. (August 2013).
4244: 3891: 3820: 3756:
Raudrant D, Rabe T (2003). "Progestogens with antiandrogenic properties".
3742: 3707: 3581: 3572: 3555: 3505: 3497: 1761: 1756: 18651: 18532: 18517: 18512: 18442: 18378: 18333: 18237: 18233: 18229: 18182: 18128: 18123: 18103: 18043: 17988: 17958: 17948: 17938: 17908: 17893: 17809: 17789: 17694: 17618: 17510: 17463: 17428: 17346: 17336: 17281: 17239: 17204: 17150: 17135: 17100: 17095: 16849: 16820: 16085: 15688: 14168: 13883: 13848: 12237: 12042: 12037: 11480: 11284: 11279: 11175: 11055: 9460: 9443: 8247: 6721: 6704: 6675: 6658: 6118:"AR-V7 and resistance to enzalutamide and abiraterone in prostate cancer" 5994: 5822: 5805: 5628: 5319:"The putative androgen receptor-A form results from in vitro proteolysis" 4985: 4640: 4294: 4277: 4180:"Regulation of the androgen receptor by post-translational modifications" 3855: 3838: 3235: 2896: 2882: 2802: 2729: 2635: 2396: 2389: 2244: 2188: 1564: 1545: 1541: 9483:
Wang L, Hsu CL, Ni J, Wang PH, Yeh S, Keng P, et al. (March 2004).
8454:
Wang Q, Udayakumar TS, Vasaitis TS, Brodie AM, Fondell JD (April 2004).
8113: 8098: 7238: 7221: 6385: 6368: 5945: 4697: 4579:
Fu M, Rao M, Wu K, Wang C, Zhang X, Hessien M, et al. (July 2004).
4196: 4179: 4102:
Li J, Al-Azzawi F (June 2009). "Mechanism of androgen receptor action".
1201:
positive regulation of intracellular estrogen receptor signaling pathway
964:
DNA-binding transcription activator activity, RNA polymerase II-specific
854: 18621: 18588: 18437: 18432: 18412: 18383: 18303: 18268: 18263: 18253: 18148: 18083: 18018: 17968: 17824: 17719: 17674: 17633: 17541: 17490: 17341: 17291: 17244: 17234: 17053: 17021: 16980: 16930: 16920: 16866: 16854: 16815: 16667: 16662: 16657: 16652: 16647: 16569: 16397: 16348: 15820: 15424: 15333: 15313: 15286: 14633: 14382: 14231: 14219: 14214: 13213: 13208: 11972: 11967: 11945: 11811: 11629: 11333: 11274: 11269: 11249: 10325: 7824: 7770: 7681: 6785:
Amir AL, Barua M, McKnight NC, Cheng S, Yuan X, Balk SP (August 2003).
5371: 4859: 3812: 3301: 3025: 2870: 2856: 2806: 2798: 2794: 2750: 2675: 2535: 2467: 2385: 2311: 2083: 2063: 1351:
activation of prostate induction by androgen receptor signaling pathway
588: 485: 435: 10031: 9827:
Poukka H, Aarnisalo P, Santti H, Jänne OA, Palvimo JJ (January 2000).
7761: 6425: 6335: 6206: 5844: 5551: 4067:
Gelmann EP (July 2002). "Molecular biology of the androgen receptor".
4044: 4027: 3963: 3650: 3597:"Androgens and androgen receptor in prostate and ovarian malignancies" 1286:
epithelial cell differentiation involved in prostate gland development
861: 376: 372: 368: 364: 360: 356: 352: 348: 344: 340: 336: 332: 328: 324: 320: 316: 312: 308: 304: 300: 296: 292: 288: 284: 280: 276: 272: 268: 264: 260: 256: 252: 248: 244: 240: 236: 232: 228: 224: 220: 216: 212: 208: 204: 200: 196: 192: 188: 184: 180: 176: 172: 168: 164: 160: 156: 152: 148: 144: 140: 136: 132: 128: 124: 120: 116: 112: 108: 104: 100: 96: 92: 88: 84: 80: 76: 18642: 18616: 18596: 18592: 18580: 18457: 18422: 18363: 18323: 18318: 18217: 18197: 18133: 18098: 18073: 18068: 18053: 17973: 17923: 17844: 17779: 17724: 17714: 17704: 17638: 17485: 17473: 17229: 17120: 17048: 17009: 16935: 16908: 16837: 16591: 16574: 16271: 16261: 16244: 15718: 15491: 14737: 12442: 11871: 11529: 11018: 10537:
Poukka H, Aarnisalo P, Karvonen U, Palvimo JJ, Jänne OA (July 1999).
9977:
Kang HY, Huang KE, Chang SY, Ma WL, Lin WJ, Chang C (November 2002).
8402:
Bevan CL, Hoare S, Claessens F, Heery DM, Parker MG (December 1999).
5778: 5478: 5449: 5032: 3049: 2933: 2904: 2866: 2827: 2695: 2204: 2196: 2162: 2067: 2047: 2006: 1965: 1947: 1935: 1415: 1004:
DNA-binding transcription factor activity, RNA polymerase II-specific
924:
RNA polymerase II cis-regulatory region sequence-specific DNA binding
655: 642: 554: 541: 443: 10580:"FHL2, a novel tissue-specific coactivator of the androgen receptor" 6826:
Mulholland DJ, Read JT, Rennie PS, Cox ME, Nelson CC (August 2003).
5450:
Jenster G, van der Korput HA, Trapman J, Brinkmann AO (March 1995).
5357: 3684:. Vitamins & Hormones. Vol. 55. Elsevier. pp. 309–52. 1993:, whereas dihydrotestosterone is the main androgenic hormone in the 18628: 18507: 18502: 18497: 18492: 18487: 18293: 18048: 17983: 17799: 17754: 17749: 17744: 17739: 17734: 17689: 17628: 17623: 17563: 16744: 16586: 15738: 13878: 12437: 12394: 11446: 7712: 4830: 3103: 2941: 2886: 2823: 2782: 2753: 2180:, a protein that activates several genes that cause muscle growth. 2098: 2017: 1923: 1920: 1818: 1745: 15516: 9315: 7855:
Li P, Lee H, Guo S, Unterman TG, Jenster G, Bai W (January 2003).
7800: 7261:
Frønsdal K, Engedal N, Slagsvold T, Saatcioglu F (November 1998).
7260: 2940:) or based on their ability to activate or inhibit transcription ( 18584: 18373: 18313: 18113: 17998: 17839: 17814: 17669: 17411: 17361: 17301: 16962: 16138: 16118: 16113: 15825: 13799: 13583: 11495: 11490: 11485: 11473: 11468: 10982: 10972: 10961: 10951: 10627:
Cheng S, Brzostek S, Lee SR, Hollenberg AN, Balk SP (July 2002).
10093: 7740: 5803: 5749: 5066:"Phenotypic heterogeneity of mutations in androgen receptor gene" 3613: 3596: 3337: 3139: 2929: 2900: 2448: 2138: 2129:
The binding of an androgen to the androgen receptor results in a
2025: 1986: 1527: 1482: 1400: 1396: 1009:
RNA polymerase II general transcription initiation factor binding
10898:
GeneReviews/NCBI/NIH/UW entry on Androgen Insensitivity Syndrome
8684: 7456: 6568:
Knee DA, Froesch BA, Nuber U, Takayama S, Reed JC (April 2001).
6366: 4357: 3483: 1915:(nuclear receptor subfamily 3, group C, member 4), is a type of 423: 18635: 18576: 18561: 18467: 16319: 16314: 16309: 16299: 16294: 16013: 15568: 15563: 15558: 15553: 14819: 14814: 14691: 14686: 14681: 14666: 14657: 14652: 14647: 14626: 14540: 14535: 14323: 14318: 14298: 14293: 14283: 14278: 14116: 14068: 14063: 14058: 14053: 14023: 14018: 14013: 14008: 13978: 13928: 13923: 13686: 13606: 13578: 13573: 13568: 13563: 13558: 13553: 13548: 13543: 13538: 13533: 13528: 13523: 13518: 13513: 13508: 13503: 13498: 13493: 13483: 13478: 13473: 13468: 13463: 13458: 13453: 13443: 13438: 13433: 13393: 13346: 13341: 13336: 13331: 13326: 13321: 13311: 13299: 13294: 13060: 13055: 13050: 12932: 12927: 12899: 12894: 12879: 12874: 12869: 12859: 12854: 12842: 12837: 12209: 12204: 12199: 12194: 12189: 12164: 12091: 12059: 12002: 11997: 11784: 11779: 11774: 11658: 11463: 11353: 11348: 11321: 11316: 11311: 11237: 10843: 7094:
Lu ML, Schneider MC, Zheng Y, Zhang X, Richie JP (April 2001).
5892: 5142: 4025: 3920: 3349: 3247: 3133: 3109: 3079: 3073: 2470:
unit 5 (TAU-5) between residues 360–485 is responsible for the
2436:
Dimerization surface involving residues 1–36, the FQNLF motif (
1877: 1782: 1729: 1437: 1251:
tertiary branching involved in mammary gland duct morphogenesis
10536: 8903:
Zhou ZX, He B, Hall SH, Wilson EM, French FS (February 2002).
8589: 7400: 7344:"CREB-binding protein in androgen receptor-mediated signaling" 7175: 4625:"Hormonal control of androgen receptor function through SIRT1" 1336:
lateral sprouting involved in mammary gland duct morphogenesis
1086:
positive regulation of NF-kappaB transcription factor activity
870: 18167: 17849: 17759: 17690:
Andarine (acetamidoxolutamide, androxolutamide, GTx-007, S-4)
17649: 16533:
Adrenosterone (11-ketoandrostenedione, 11-oxoandrostenedione)
16363: 16341: 16336: 16304: 16193: 16188: 16133: 16128: 16123: 16067: 15976: 15971: 15966: 15961: 15956: 15951: 15946: 15941: 15889: 15884: 15872: 15867: 15862: 15857: 15845: 15840: 15835: 15830: 15799: 15766: 15761: 15756: 15703: 15698: 15693: 15668: 15626: 15621: 15616: 15611: 15606: 15601: 15573: 15526: 15521: 15467: 15462: 15457: 15452: 15429: 15204: 15189: 15184: 15179: 15174: 15169: 15164: 15159: 15154: 15149: 15139: 15129: 15124: 15109: 15104: 15094: 15089: 15084: 15074: 15069: 15064: 15059: 15054: 15049: 15044: 15014: 15009: 14999: 14994: 14979: 14974: 14969: 14964: 14898: 14893: 14888: 14861: 14836: 14804: 14797: 14792: 14698: 14676: 14671: 14643: 14621: 14616: 14611: 14606: 14501: 14496: 14441: 14434: 14429: 14414: 14387: 14048: 14043: 14038: 14033: 14028: 14003: 13998: 13993: 13988: 13983: 13973: 13968: 13963: 13958: 13953: 13948: 13943: 13938: 13933: 13913: 13908: 13903: 13898: 13893: 13888: 13873: 13868: 13693: 13681: 13676: 13671: 13666: 13634: 13629: 13428: 13418: 13413: 13408: 13403: 13398: 13388: 13383: 13378: 13373: 13289: 13279: 13272: 13267: 13262: 13257: 13247: 13191: 13186: 13181: 13176: 13171: 13166: 13161: 13082: 13077: 13072: 13016: 13011: 12910: 12889: 12884: 12758: 12753: 12748: 12743: 12738: 12733: 11940: 11705: 11700: 11695: 11685: 11680: 11675: 11665: 11653: 11603: 11583: 11524: 11512: 11507: 11431: 11424: 11419: 11409: 11402: 11397: 11328: 11259: 11232: 11227: 11210: 11205: 11200: 11195: 11190: 11180: 11168: 11163: 11141: 11131: 11126: 11116: 9908: 9190:
Yang F, Li X, Sharma M, Zarnegar M, Lim B, Sun Z (May 2001).
8844:
Yeh S, Lin HK, Kang HY, Thin TH, Lin MF, Chang C (May 1999).
8322:"Androgen receptor interacts with a novel MYST protein, HBO1" 8058:
Gaughan L, Logan IR, Cook S, Neal DE, Robson CN (July 2002).
7034: 6993: 3518: 3367: 3355: 3313: 3283: 3277: 3265: 3253: 3241: 3229: 3217: 3205: 3199: 3181: 3175: 3151: 3121: 3115: 3091: 3061: 3037: 3013: 3007: 10967:
Overview of all the structural information available in the
10946:
Overview of all the structural information available in the
8453: 6066: 5500: 1151:
negative regulation of extrinsic apoptotic signaling pathway
18600: 17913: 16390: 16385: 16380: 16370: 16358: 16353: 16200: 16183: 16047: 16042: 16037: 16008: 16003: 15936: 15931: 15926: 15921: 15916: 15911: 15906: 15901: 15852: 15746: 15708: 15683: 15678: 15673: 15656: 15548: 15541: 15536: 15417: 15412: 15407: 15402: 15397: 15392: 15387: 15382: 15372: 15365: 15355: 15350: 15338: 15328: 15323: 15306: 15301: 15296: 15279: 15274: 15269: 15244: 15239: 15234: 14952: 14947: 14942: 14937: 14932: 14871: 14846: 14841: 14782: 14777: 14772: 14767: 14762: 14757: 14752: 14747: 14742: 14713: 14708: 14601: 14596: 14591: 14586: 14572: 14567: 14562: 14557: 14552: 14523: 14518: 14513: 14479: 14474: 14469: 14464: 14459: 14454: 14419: 14407: 14402: 14397: 14350: 14345: 14340: 14335: 14330: 14251: 14236: 14226: 14202: 14197: 14183: 14178: 14173: 14163: 14158: 14146: 14141: 14085: 14080: 13858: 13843: 13838: 13826: 13821: 13654: 13649: 13644: 13488: 13423: 13368: 13363: 13358: 13242: 13237: 13232: 13156: 13151: 13146: 13141: 13136: 13131: 13126: 13121: 13116: 13099: 13094: 13038: 13033: 13001: 12996: 12991: 12981: 12976: 12969: 12964: 12959: 12954: 12944: 12939: 12922: 12780: 12775: 12770: 12698: 12159: 12154: 12149: 12144: 12139: 12134: 12047: 12032: 12009: 11982: 11955: 11950: 11915: 11893: 11888: 11883: 11866: 11861: 11851: 11841: 11791: 11749: 11744: 11727: 11722: 11717: 11615: 11610: 11598: 11556: 11551: 11541: 11456: 11451: 11441: 11360: 11343: 11306: 11294: 11289: 11264: 11222: 11151: 11146: 11121: 11104: 11099: 11094: 11089: 11084: 11074: 10495: 10355:
Lee YF, Shyr CR, Thin TH, Lin WJ, Chang C (December 1999).
10175: 9868:
Liu Y, Kim BO, Kao C, Jung C, Dalton JT, He JJ (May 2004).
9777: 8014:
Wang L, Lin HK, Hu YC, Xie S, Yang L, Chang C (July 2004).
7944: 7306: 6518: 6369:"Androgen receptor antagonists for prostate cancer therapy" 3984: 3343: 3319: 3271: 3211: 3193: 3145: 3031: 2995: 2989: 2264: 2154: 1839: 1806: 10626: 9826: 9695: 9233:"AR and ER interaction with a p21-activated kinase (PAK6)" 8320:
Sharma M, Zarnegar M, Li X, Lim B, Sun Z (November 2000).
5976: 5659: 3635: 2948:). Inhibitors that target alternative functional domains ( 2520:
proteins (containing the LXXLL or preferably FXXFL motifs)
2114:
The primary mechanism of action for androgen receptors is
1176:
positive regulation of transcription by RNA polymerase III
18283: 16032: 15661: 15651: 15531: 14927: 14484: 13833: 13284: 13021: 12515: 11987: 11816: 11806: 11801: 11593: 11588: 10017: 9356: 9274: 8361:
Ueda T, Mawji NR, Bruchovsky N, Sadar MD (October 2002).
8137:
The Journal of Steroid Biochemistry and Molecular Biology
7973:
Rigas AC, Ozanne DM, Neal DE, Robson CN (November 2003).
7903: 4316: 3361: 3307: 2719:
At androgen receptors; measured in human prostate tissue.
2057: 1371:
negative regulation of transcription by RNA polymerase II
1221:
positive regulation of transcription by RNA polymerase II
17374:
17α-Alkylated 5α-dihydro-19-nortestosterone derivatives:
10577: 9654: 9572: 8549:
Tan JA, Hall SH, Petrusz P, French FS (September 2000).
8401: 8360: 6567: 6067:
Silberstein JL, Taylor MN, Antonarakis ES (April 2016).
6025: 5977:
Kaku N, Matsuda K, Tsujimura A, Kawata M (August 2008).
5928:
Tan MH, Li J, Xu HE, Melcher K, Yong EL (January 2015).
3878:
Davison SL, Bell R (April 2006). "Androgen physiology".
2562:
patients and is predictive of resistance to some drugs.
1156:
transcription initiation from RNA polymerase II promoter
679: 16877:
7α-Methyl-19-norandrostenedione (MENT dione, trestione)
12233: 10814:"Androgen physiology: receptor and metabolic disorders" 10667: 9949: 9531: 9025: 8784: 7220:
Kim J, Jia L, Stallcup MR, Coetzee GA (February 2005).
6825: 6702: 6410:"Chemistry and structural biology of androgen receptor" 6188: 5014: 3798: 1942:. The androgen receptor is most closely related to the 30: 17571:
5α-Dihydro-17α-ethynyl-19-nortestosterone derivatives:
10865:
Molecular Mechanisms of Androgen Receptor Interactions
10844:"The Androgen Receptor Gene Mutations Database Server" 9066: 8944:
Gao T, Brantley K, Bolu E, McPhaul MJ (October 1999).
8943: 6784: 6115: 5206: 5063: 3985:
Walters KA, Simanainen U, Handelsman DJ (March 2010).
3720: 2302:
have been linked to a number of additional disorders.
2133:
in the receptor that, in turn, causes dissociation of
10253:
Ting HJ, Yeh S, Nishimura K, Chang C (January 2002).
10252: 8279:
Wang Q, Sharma D, Ren Y, Fondell JD (November 2002).
8134: 7972: 7565: 7415: 7341: 7219: 7093: 6907: 6866: 5610: 4537: 1386:
regulation of protein localization to plasma membrane
844: 18657: 10757: 9736: 9397: 9189: 8548: 8278: 8057: 6746:"Linking beta-catenin to androgen-signaling pathway" 6611:"BAG-1L protein enhances androgen receptor function" 5400: 3679: 1206:
negative regulation of epithelial cell proliferation
1141:
positive regulation of cell population proliferation
1121:
positive regulation of integrin biosynthetic process
1101:
negative regulation of integrin biosynthetic process
1076:
negative regulation of cell population proliferation
17005:
Normethandrone (methylestrenolone, normethisterone)
16162: 10708: 10211: 10179:
Biochemical and Biophysical Research Communications
9661:
Biochemical and Biophysical Research Communications
9148: 8785:Miyamoto H, Yeh S, Wilding G, Chang C (June 1998). 8319: 7497: 7309:
Biochemical and Biophysical Research Communications
6608: 4833:
Biochemical and Biophysical Research Communications
4728: 2932:
can either be classified based on their structure (
2260:In humans, the androgen receptor is encoded by the 1953:The main function of the androgen receptor is as a 1950:in higher dosages can block the androgen receptor. 1146:
positive regulation of transcription, DNA-templated
10413: 9737:Kang HY, Yeh S, Fujimoto N, Chang C (March 1999). 9230: 7663: 6743: 6656: 6318:Elshan ND, Rettig MB, Jung ME (22 November 2018). 6240:"Androgen receptor (AR) coregulators: an overview" 6191:"Androgen receptors, sex behavior, and aggression" 5888: 5886: 5107: 3427: 3425: 3423: 3406: 3404: 3402: 17217:17α-Alkylated 5α-dihydrotestosterone derivatives: 10052: 9107: 8644:He B, Minges JT, Lee LW, Wilson EM (March 2002). 8643: 5708: 4865: 4787: 4488: 4398: 2624: 626: 525: 18719: 16462: 13733: 9976: 9437: 9435: 9270: 9268: 8902: 8639: 8637: 8635: 8495: 8493: 8491: 8449: 8447: 8176: 8174: 8053: 8051: 7854: 7342:Aarnisalo P, Palvimo JJ, Jänne OA (March 1998). 6317: 4971: 4729:Fix C, Jordan C, Cano P, Walker WH (July 2004). 2009:, whilst dihydrotestosterone is responsible for 1296:regulation of transcription by RNA polymerase II 17436:5α-Dihydro-17α-ethynyltestosterone derivatives: 10903:OMIM entries on Androgen Insensitivity Syndrome 9442:Lin HK, Hu YC, Lee DK, Chang C (October 2004). 7302: 7300: 7298: 6698: 6696: 6694: 6657:Song LN, Coghlan M, Gelmann EP (January 2004). 6652: 6650: 6648: 6646: 6459: 6455: 6453: 6109: 6060: 5883: 5849:. Hormone Receptors: Structures and Functions. 5799: 5797: 5709:Langley E, Zhou ZX, Wilson EM (December 1995). 5316: 5202: 5200: 5198: 5064:Rajender S, Singh L, Thangaraj K (March 2007). 4618: 4616: 4439: 3832: 3830: 3420: 3399: 16887:11β-Methyl-19-nortestosterone dodecylcarbonate 10354: 10135:Yuan X, Lu ML, Li T, Balk SP (December 2001). 8843: 7614: 6934: 5927: 5103: 5101: 4671: 4622: 4275: 3432:GRCm38: Ensembl release 89: ENSMUSG00000046532 2956:) of the protein are still under development. 2577:activity may contribute to the progression of 1216:regulation of systemic arterial blood pressure 17654:Tooltip Selective androgen receptor modulator 17299:17α-Alkylated 19-nortestosterone derivatives: 16448: 16423:transcription factor/coregulator deficiencies 15494:β-Scaffold factors with minor groove contacts 11004: 10751: 10702: 10661: 10620: 10571: 10530: 10489: 10448: 10407: 10348: 10305: 10246: 10212:Ueda T, Bruchovsky N, Sadar MD (March 2002). 10205: 10169: 10128: 10087: 10046: 10011: 9970: 9943: 9902: 9867: 9861: 9820: 9730: 9689: 9566: 9525: 9482: 9476: 9441: 9432: 9391: 9309: 9265: 9224: 9183: 9142: 9101: 9060: 9019: 8978: 8937: 8896: 8837: 8632: 8583: 8542: 8488: 8444: 8395: 8354: 8313: 8272: 8223: 8171: 8048: 8007: 7966: 7938: 7848: 7794: 7734: 7706: 7657: 7608: 7559: 6460:Lin HK, Yeh S, Kang HY, Chang C (June 2001). 6407: 6313: 6311: 6237: 6189:Cunningham RL, Lumia AR, McGinnis MY (2012). 5317:Gregory CW, He B, Wilson EM (December 2001). 5257: 4136: 3836: 2924:have been developed, primarily targeting the 2916:The AR is an important therapeutic target in 2601: 2512:AF-2 binds either the N-terminal FXXFL motif 2207:. The AR acetylation site is a key target of 1376:cellular response to steroid hormone stimulus 17705:Enobosarm (ostarine, MK-2866, GTx-024, S-22) 10134: 9771: 9648: 9607: 9350: 8984: 8778: 8719: 8678: 8128: 8092: 8013: 7897: 7524: 7518: 7491: 7450: 7409: 7295: 7213: 7169: 7134: 7128: 7087: 7028: 6928: 6901: 6860: 6819: 6778: 6737: 6691: 6643: 6609:Froesch BA, Takayama S, Reed JC (May 1998). 6561: 6512: 6450: 6408:Gao W, Bohl CE, Dalton JT (September 2005). 6019: 5970: 5794: 5653: 5604: 5545: 5310: 5195: 5136: 5057: 5008: 4613: 4351: 4310: 4269: 4226: 4220: 4177: 4171: 4060: 3978: 3943: 3914: 3871: 3827: 3755: 3749: 3553: 1985:to dihydrotestosterone, an even more potent 17456:17α-Ethynyl-19-nortestosterone derivatives: 9613: 8180: 7335: 7254: 6987: 6602: 6360: 6272: 5743: 5702: 5443: 5351: 5251: 5098: 4965: 4916: 4824: 4781: 4578: 4101: 3877: 3792: 3714: 3673: 3629: 3594: 3588: 3512: 3411:GRCh38: Ensembl release 89: ENSG00000169083 2506:) – Ligand binding domain (LBD) containing 1081:positive regulation of cell differentiation 17178:Methylclostebol (chloromethyltestosterone) 17073:5α-Dihydro-19-nortestosterone derivatives: 16455: 16441: 11011: 10997: 10454: 6308: 6278: 3547: 3477: 3387:Discovery and development of antiandrogens 2608: 2594: 1781: 1381:cellular response to testosterone stimulus 1161:regulation of transcription, DNA-templated 17399:17α-Vinyl-19-nortestosterone derivatives: 17015:Oxabolone cipionate (oxabolone cypionate) 16631:DHEA (androstenolone, prasterone; 5-DHEA) 16475: 10920:at the U.S. National Library of Medicine 10811: 10783: 10734: 10685: 10644: 10603: 10554: 10513: 10472: 10431: 10390: 10380: 10288: 10278: 10229: 10152: 10111: 10070: 9994: 9926: 9885: 9844: 9803: 9754: 9713: 9672: 9631: 9590: 9549: 9508: 9459: 9415: 9374: 9333: 9292: 9248: 9207: 9166: 9125: 9084: 9043: 9002: 8961: 8920: 8879: 8869: 8820: 8810: 8761: 8751: 8702: 8661: 8615: 8566: 8525: 8471: 8427: 8378: 8337: 8296: 8255: 8229: 8206: 8075: 8031: 7990: 7921: 7880: 7823: 7769: 7689: 7640: 7591: 7542: 7474: 7433: 7377: 7367: 7278: 7237: 7152: 7111: 7070: 7060: 7011: 6970: 6960: 6884: 6843: 6802: 6761: 6720: 6674: 6626: 6585: 6544: 6495: 6485: 6433: 6384: 6343: 6255: 6214: 6141: 6092: 6043: 6002: 5953: 5821: 5777: 5767: 5726: 5685: 5636: 5587: 5577: 5528: 5518: 5477: 5467: 5426: 5334: 5293: 5283: 5178: 5168: 5081: 5040: 4940: 4899: 4866:Šimčíková D, Heneberg P (December 2019). 4764: 4754: 4705: 4648: 4596: 4555: 4514: 4465: 4416: 4375: 4334: 4293: 4252: 4195: 4154: 4043: 4002: 3924:Journal of Endocrinological Investigation 3854: 3612: 3571: 2050:, working through both intra-ovarian and 999:DNA-binding transcription factor activity 17106:Chlorodehydromethylandrostenediol (CDMA) 10861: 10841: 8725: 8499: 8181:Bai S, He B, Wilson EM (February 2005). 6401: 4722: 4276:Heemers HV, Tindall DJ (December 2007). 2565: 2344:Structural domains of the two isoforms ( 2339: 1976: 1919:that is activated by binding any of the 1893: 1111:intracellular receptor signaling pathway 18707:List of androgens and anabolic steroids 17093:17α-Alkylated testosterone derivatives: 10311: 7525:Lee DK, Duan HO, Chang C (March 2000). 7135:Lee DK, Duan HO, Chang C (March 2001). 5258:Wilson CM, McPhaul MJ (February 1994). 4925:"Human androgen insensitivity syndrome" 4066: 1311:prostate gland epithelium morphogenesis 18720: 17111:Chlorodehydromethyltestosterone (CDMT) 16867:Testifenon (testiphenon, testiphenone) 3554:Choong CS, Wilson EM (December 1998). 2820:Selective androgen receptor modulators 2191:, which directly promotes AR-mediated 2104: 2058:Maintenance of male skeletal integrity 1136:positive regulation of gene expression 1126:positive regulation of phosphorylation 17392:Norvinisterone (vinylnortestosterone) 16926:Bolmantalate (nandrolone adamantoate) 16921:Bolandione (19-nor-4-androstenedione) 16636:DHEA enanthate (prasterone enanthate) 16436: 16161: 15490: 13732: 12232: 11035: 11034: 10992: 5021:The Journal of Clinical Investigation 4922: 4178:Coffey K, Robson CN (November 2012). 3949: 3837:Heinlein CA, Chang C (October 2002). 2167:insulin-like growth factor 1 receptor 1276:regulation of prostatic bud formation 631: 592: 587: 530: 489: 484: 18662:Tooltip Sex hormone-binding globulin 17409:17α-Ethynyltestosterone derivatives: 16688:Polytestosterone phloretin phosphate 4032:Journal of Bone and Mineral Research 2980:Androgen receptor has been shown to 2463:-activated transcriptional activity 17332:Methylhydroxynandrolone (MOHN, MHN) 17037:Trenbolone hexahydrobenzylcarbonate 16697:5α-Dihydrotestosterone derivatives: 16565:Androstenedione (4-androstenedione) 12177:(1.6) Basic helix-span-helix (bHSH) 10674:The Journal of Biological Chemistry 10543:The Journal of Biological Chemistry 10461:The Journal of Biological Chemistry 10420:The Journal of Biological Chemistry 10218:The Journal of Biological Chemistry 10141:The Journal of Biological Chemistry 9983:The Journal of Biological Chemistry 9915:The Journal of Biological Chemistry 9874:The Journal of Biological Chemistry 9833:The Journal of Biological Chemistry 9743:The Journal of Biological Chemistry 9702:The Journal of Biological Chemistry 9620:The Journal of Biological Chemistry 9614:Lu J, Danielsen M (November 1998). 9538:The Journal of Biological Chemistry 9404:The Journal of Biological Chemistry 9363:The Journal of Biological Chemistry 9281:The Journal of Biological Chemistry 9196:The Journal of Biological Chemistry 9114:The Journal of Biological Chemistry 9032:The Journal of Biological Chemistry 8991:The Journal of Biological Chemistry 8650:The Journal of Biological Chemistry 8460:The Journal of Biological Chemistry 8367:The Journal of Biological Chemistry 8326:The Journal of Biological Chemistry 8285:The Journal of Biological Chemistry 8064:The Journal of Biological Chemistry 8020:The Journal of Biological Chemistry 7979:The Journal of Biological Chemistry 7531:The Journal of Biological Chemistry 7267:The Journal of Biological Chemistry 7141:The Journal of Biological Chemistry 7100:The Journal of Biological Chemistry 7000:The Journal of Biological Chemistry 6873:The Journal of Biological Chemistry 6791:The Journal of Biological Chemistry 6750:The Journal of Biological Chemistry 6615:The Journal of Biological Chemistry 6574:The Journal of Biological Chemistry 6238:Heinlein CA, Chang C (April 2002). 6122:The New England Journal of Medicine 6032:The Journal of Biological Chemistry 5715:The Journal of Biological Chemistry 5507:The Journal of Biological Chemistry 5456:The Journal of Biological Chemistry 4585:The Journal of Biological Chemistry 4405:The Journal of Biological Chemistry 4364:The Journal of Biological Chemistry 4227:Yavuz S, Kabbech H (October 2023). 2911: 2161:, which, in turn, is translated by 1306:morphogenesis of an epithelial fold 1236:positive regulation of MAPK cascade 1131:androgen receptor signaling pathway 13: 17389:17α-Vinyltestosterone derivatives: 17151:Methandriol (methylandrostenediol) 10850:from the original on 22 April 2008 10821:Endocrinology of Male Reproduction 10804: 9579:Journal of Molecular Endocrinology 7633:10.1128/MCB.24.24.10529-10541.2004 7226:Journal of Molecular Endocrinology 5323:Journal of Molecular Endocrinology 4942:10.1002/j.1939-4640.1995.tb00533.x 4130: 3560:Journal of Molecular Endocrinology 2959: 2542: 2451:, and X = any amino acid residue a 2199:and contact-independent growth of 2073: 1331:regulation of developmental growth 1321:reproductive structure development 1281:mammary gland alveolus development 14: 18744: 17429:Ethisterone (ethynyltestosterone) 17146:Metandienone (methandrostenolone) 16976:Methoxydienone (methoxygonadiene) 16587:Boldione (1,4-androstadienedione) 16538:Androstenediol (5-androstenediol) 16503:4-Dehydroepiandrosterone (4-DHEA) 10981:(Mouse Androgen receptor) at the 10960:(Human Androgen receptor) at the 10891: 10455:Hsiao PW, Chang C (August 1999). 3880:Seminars in Reproductive Medicine 2629:Tooltip Relative binding affinity 2183:Androgen receptor is modified by 1014:steroid hormone receptor activity 16:Mammalian protein found in humans 18702:Progesterone receptor modulators 17193:Methyltestosterone 3-hexyl ether 17156:Methandriol bisenanthoyl acetate 17116:Chloromethylandrostenediol (CMA) 16951:Dimethandrolone dodecylcarbonate 16710:1-Androsterone (1-andro, 1-DHEA) 6537:10.1128/MCB.23.20.7189-7197.2003 5083:10.1111/j.1745-7262.2007.00250.x 4507:10.1128/mcb.23.23.8563-8575.2003 4458:10.1128/mcb.22.10.3373-3388.2002 3770:10.2165/00003495-200363050-00003 3595:Meehan KL, Sadar MD (May 2003). 3086:Epidermal growth factor receptor 2456:Polyglutamine repeat (AR-B only) 1938:and then translocating into the 1326:regulation of catalytic activity 860: 853: 615: 608: 602: 579: 514: 507: 501: 476: 29: 16874:19-Nortestosterone derivatives: 16164:(0) Other transcription factors 15448:transcriptional enhancer factor 11065:Activating transcription factor 9501:10.1128/MCB.24.5.2202-2213.2004 8518:10.1128/MCB.23.6.2135-2150.2003 8230:Bai S, Wilson EM (March 2008). 8199:10.1128/MCB.25.4.1238-1257.2005 7750:International Journal of Cancer 7394: 6231: 6182: 6158: 5921: 5838: 5494: 5394: 4665: 4572: 4531: 4482: 4433: 4392: 4139:"Alternative androgen pathways" 4116:10.1016/j.maturitas.2009.03.008 4095: 4019: 3723:Pharmacology & Therapeutics 3521:Reproductive Biomedicine Online 2975: 2893:N-Terminal domain antiandrogens 2722: 2713: 2474:(activity without bound ligand) 2388:truncated (lacks the first 187 2281:androgen insensitivity syndrome 2274: 2185:post-translational modification 2034:estrogen insensitivity syndrome 2030:androgen insensitivity syndrome 1301:seminiferous tubule development 1246:reproductive system development 1181:protein complex oligomerization 17889:15β-Hydroxycyproterone acetate 17780:OPK-88004 (LY-2452473, TT-701) 10823:. Endotext.org. Archived from 10812:Brinkmann AO (November 2009). 9784:Molecular and Cellular Biology 9489:Molecular and Cellular Biology 8506:Molecular and Cellular Biology 8500:He B, Wilson EM (March 2003). 8408:Molecular and Cellular Biology 8236:Molecular and Cellular Biology 8187:Molecular and Cellular Biology 7861:Molecular and Cellular Biology 7816:10.1016/j.steroids.2004.05.011 7621:Molecular and Cellular Biology 6525:Molecular and Cellular Biology 5617:Molecular and Cellular Biology 4629:Molecular and Cellular Biology 4495:Molecular and Cellular Biology 4446:Molecular and Cellular Biology 3952:Medical and Pediatric Oncology 3459: 3441: 2834: 2305: 2226: 2011:secondary male characteristics 2007:primary sexual characteristics 1241:in utero embryonic development 1196:male somatic sex determination 871:More reference expression data 833:More reference expression data 1: 18687:Receptor/signaling modulators 17444:17α-Ethynyl-3β-androstanediol 17439:17α-Ethynyl-3α-androstanediol 16882:11β-Methyl-19-nortestosterone 15378:Interferon regulatory factors 13617:(2.5) Alternating composition 12813:General transcription factors 10715:Molecular Biology of the Cell 10515:10.1158/0008-5472.CAN-07-6059 10072:10.1158/0008-5472.CAN-04-1121 7873:10.1128/MCB.23.1.104-118.2003 7584:10.1158/0008-5472.CAN-08-3821 7321:10.1016/S0006-291X(03)01021-0 7191:10.1016/S0361-9230(01)00583-4 5907:10.1158/0008-5472.CAN-05-2389 5122:10.1016/s0090-4295(98)00481-6 4845:10.1016/S0006-291X(88)81214-2 4336:10.1158/0008-5472.CAN-04-1837 3690:10.1016/S0083-6729(08)60938-3 3682:Regulation of androgen action 3533:10.1016/S1472-6483(10)60802-4 3392: 2732:, which is by definition 100% 2097:(PAIS) which are a result of 1834:Available protein structures: 1291:epithelial cell morphogenesis 1231:multicellular organism growth 1211:regulation of gene expression 1166:cell population proliferation 929:protein dimerization activity 919:sequence-specific DNA binding 600: 499: 18697:Estrogen receptor modulators 18144:Trimethyltrienolone (R-2956) 17516:Lynestrenol phenylpropionate 16904:19-Nordehydroepiandrosterone 14663:Octamer transcription factor 11371:(1.2) Basic helix-loop-helix 8149:10.1016/0960-0760(92)90088-Z 7403:US Endocrine Society Meeting 6294:10.1016/0022-4731(89)90301-4 5170:10.1371/journal.pone.0195046 4184:The Journal of Endocrinology 4137:Masiutin M, Yadav M (2023). 4069:Journal of Clinical Oncology 3735:10.1016/0163-7258(83)90023-2 2335: 2318: 1341:male genitalia morphogenesis 1186:transcription, DNA-templated 969:transcription factor binding 7: 18728:Genes on human chromosome X 18692:Androgens and antiandrogens 18463:Ralaniten acetate (EPI-506) 17879:7α-Thiomethylspironolactone 17594:Medroxyprogesterone acetate 16956:Dimethandrolone undecanoate 16767:Dihydromethylandrostenediol 16558:Androstenediol dipropionate 11437:Myogenic regulatory factors 8726:Yeh S, Chang C (May 1996). 5853:. Academic Press: 439–481. 5666:The Journal of Cell Biology 3375: 2744: 2573:Aberrant androgen receptor 2499:nuclear localization signal 2356: 2250: 1971: 1316:Leydig cell differentiation 10: 18749: 16782:Dihydrotestosterone esters 16735:11-Ketodihydrotestosterone 16548:Androstenediol 17β-acetate 16528:11β-Hydroxyandrostenedione 16513:4,17α-Dimethyltestosterone 10939:gene details page in the 6324:Medicinal Research Reviews 5934:Acta Pharmacologica Sinica 5229:10.1038/s41586-022-04975-9 5070:Asian Journal of Andrology 4892:10.1038/s41598-019-54976-4 3382:Membrane androgen receptor 3068:Death associated protein 6 2863:Nonsteroidal antiandrogens 2584: 2409: 2365:of the androgen receptor ( 2109: 1116:prostate gland development 1060:protein-containing complex 914:signaling receptor binding 18679: 18569: 18560: 17858: 17647: 17586:Progesterone derivatives: 17377:5α-Dihydronorethandrolone 16946:Dimethandrolone buciclate 16776:androstanolone, stanolone 16772:Dihydrotestosterone (DHT) 16730:7β-Hydroxyepiandrosterone 16619:Cloxotestosterone acetate 16543:Androstenediol 3β-acetate 16495:Testosterone derivatives: 16487: 16480:Tooltip Androgen receptor 16473: 16418: 16280: 16240: 16209: 16174: 16170: 16157: 16099: 16076: 16058: 15808: 15782: 15734: 15637: 15584: 15504: 15500: 15486: 15438: 15257:(3.5) Tryptophan clusters 15255: 15215: 14911: 14728: 14368: 14094: 13782: 13763: 13751: 13747: 13728: 13702: 13615: 13594: 12796: 12716: 12687: 12667: 12642: 12605: 12524: 12420: 12268: 12249: 12245: 12228: 12175: 12120: 12018: 11928: 11904: 11827: 11760: 11624: 11574: 11383: 11369: 11047: 11043: 11030: 10862:Thompson J (2006-09-30). 10842:Gottlieb B (2007-07-24). 8596:British Journal of Cancer 7716:Molecular Cancer Research 6085:10.1007/s11934-016-0584-4 5859:10.1016/bs.vh.2023.01.001 5520:10.1074/jbc.REV120.012411 3991:Human Reproduction Update 3467:"Mouse PubMed Reference:" 3449:"Human PubMed Reference:" 3296:Small heterodimer partner 3056:Cyclin-dependent kinase 7 2704: 2694: 2684: 2674: 2664: 2654: 2644: 2634: 2622: 2619: 2489:Contains two Zinc fingers 2233:steroid hormone receptors 1962:regulates gene expression 1876: 1856: 1838: 1833: 1829: 1817: 1805: 1797: 1792: 1780: 1775: 1760: 1755: 1751: 1744: 1728: 1709: 1694: 1690: 1669: 1645: 1638: 1623: 1619: 1586: 1582: 1575: 1562: 1558: 1539: 1535: 1526: 1513: 1509: 1494: 1490: 1481: 1468: 1464: 1449: 1445: 1436: 1421: 1414: 1410: 1394: 944:nuclear receptor activity 889: 885: 868: 852: 843: 830: 779: 770: 717: 708: 678: 670: 666: 649: 636: 599: 578: 569: 565: 548: 535: 498: 475: 466: 462: 417: 414: 404: 397: 392: 73: 68: 51: 46: 41: 37: 28: 23: 18392:-Butylbenzenesulfonamide 17579:5α-Dihydronorethisterone 17574:5α-Dihydrolevonorgestrel 17536:norethisterone enanthate 17505:levonorgestrel butanoate 17382:5α-Dihydronormethandrone 17235:Mebolazine (dimethazine) 17225:Desoxymethyltestosterone 17166:Methandriol dipropionate 16963:LS-1727 (nandrolone 17β- 16899:19-Nor-5-androstenedione 16757:Dihydroethyltestosterone 16553:Androstenediol diacetate 16078:(4.10) Cold-shock domain 10922:Medical Subject Headings 10819:. In McLachlan R (ed.). 10556:10.1074/jbc.274.27.19441 10474:10.1074/jbc.274.32.22373 10382:10.1073/pnas.96.26.14724 10100:Endocrine-Related Cancer 9633:10.1074/jbc.273.47.31528 7910:Human Molecular Genetics 7280:10.1074/jbc.273.48.31853 7013:10.1074/jbc.272.28.17485 6628:10.1074/jbc.273.19.11660 6373:Endocrine-Related Cancer 5728:10.1074/jbc.270.50.29983 2813: 2554:that can be detected in 2550:is an androgen receptor 2373:) have been identified: 2151:hormone response element 1361:protein deubiquitination 807:anterior amygdaloid area 18523:Topilutamide (fluridil) 17884:11α-Hydroxyprogesterone 16894:19-Nor-5-androstenediol 16794:Drostanolone propionate 11024:intracellular receptors 10633:Molecular Endocrinology 9756:10.1074/jbc.274.13.8570 9448:Molecular Endocrinology 9335:10.1210/mend.14.12.0569 9322:Molecular Endocrinology 9237:Molecular Endocrinology 9073:Molecular Endocrinology 8963:10.1210/mend.13.10.0352 8950:Molecular Endocrinology 8909:Molecular Endocrinology 8871:10.1073/pnas.96.10.5458 8812:10.1073/pnas.95.13.7379 8753:10.1073/pnas.93.11.5517 8691:Molecular Endocrinology 8568:10.1210/endo.141.9.7680 7670:The Biochemical Journal 7544:10.1074/jbc.275.13.9308 7422:Molecular Endocrinology 7179:Brain Research Bulletin 7062:10.1073/pnas.0307161101 6709:Molecular Endocrinology 6663:Molecular Endocrinology 6073:Current Urology Reports 5810:Molecular Endocrinology 5756:Molecular Endocrinology 5579:10.1073/pnas.0408819102 5469:10.1074/jbc.270.13.7341 4810:10.1126/science.3353726 4756:10.1073/pnas.0404278101 4143:WikiJournal of Medicine 4081:10.1200/JCO.2002.10.018 3843:Molecular Endocrinology 3639:Pharmacological Reviews 3601:Frontiers in Bioscience 2841:Steroidal antiandrogens 2556:circulating tumor cells 2443:FXXLF motif; where F = 2255: 1722:Chr X: 97.19 – 97.37 Mb 1715:Chr X: 67.54 – 67.73 Mb 18408:-Desmethylenzalutamide 18114:SC-5233 (spirolactone) 17532:norethisterone acetate 17171:Methandriol propionate 17042:Trenbolone undecanoate 16914:Bolandiol dipropionate 16762:Dihydrofluoxymesterone 16725:5α-Androst-2-en-17-one 16580:Boldenone undecylenate 10727:10.1091/mbc.01-10-0513 10687:10.1074/jbc.M408972200 10646:10.1210/mend.16.7.0870 10596:10.1093/emboj/19.3.359 10433:10.1074/jbc.M111218200 10280:10.1073/pnas.022469899 10231:10.1074/jbc.M108255200 10191:10.1006/bbrc.2001.4758 10154:10.1074/jbc.M108404200 9996:10.1074/jbc.M205603200 9928:10.1074/jbc.M108855200 9887:10.1074/jbc.M314321200 9715:10.1074/jbc.M108312200 9674:10.1006/bbrc.1998.8974 9551:10.1074/jbc.M209741200 9417:10.1074/jbc.M203811200 9376:10.1074/jbc.274.6.3700 9294:10.1074/jbc.M109491200 9250:10.1210/mend.16.1.0753 9209:10.1074/jbc.M010311200 9168:10.1038/sj.onc.1205638 9127:10.1074/jbc.M000660200 9086:10.1210/mend.16.4.0798 9045:10.1074/jbc.M206374200 9004:10.1074/jbc.M312563200 8922:10.1210/mend.16.2.0765 8704:10.1210/mend.13.1.0214 8663:10.1074/jbc.M111975200 8608:10.1054/bjoc.2001.2179 8473:10.1074/jbc.M400970200 8420:10.1128/mcb.19.12.8383 8380:10.1074/jbc.M203313200 8339:10.1074/jbc.M004838200 8298:10.1074/jbc.M206061200 8077:10.1074/jbc.M203423200 8033:10.1074/jbc.M313963200 7992:10.1074/jbc.M306219200 7476:10.1038/sj.onc.1208200 7435:10.1210/mend.15.5.0641 7369:10.1073/pnas.95.5.2122 7154:10.1074/jbc.M002285200 7113:10.1074/jbc.M006598200 6962:10.1073/pnas.190353897 6886:10.1074/jbc.M200545200 6845:10.1038/sj.onc.1206802 6804:10.1074/jbc.M301208200 6763:10.1074/jbc.M111962200 6587:10.1074/jbc.M010841200 6487:10.1073/pnas.121173298 6257:10.1210/edrv.23.2.0460 6045:10.1074/jbc.M302460200 5769:10.1210/mend.12.8.0153 5407:Nucleic Acids Research 5285:10.1073/pnas.91.4.1234 4598:10.1074/jbc.M313466200 4557:10.1038/sj.onc.1209231 4418:10.1074/jbc.M000660200 4377:10.1074/jbc.M413992200 4233:Nucleic Acids Research 3260:Retinoblastoma protein 2920:. Thus many different 2774:dehydroepiandrosterone 2405:– 110 kDa; full length 2392:), which results from 2353: 1900: 1261:male gonad development 1226:animal organ formation 815:triceps brachii muscle 18400:-Desmethylapalutamide 17929:Chlormadinone acetate 17874:7α-Thiospironolactone 17745:LGD-2941 (LGD-122941) 17735:LG121071 (LGD-121071) 17609:3-Keto-5α-abiraterone 17589:6α-Methylprogesterone 17528:Norethisterone esters 17501:Levonorgestrel esters 17417:Ethinylandrostenediol 17267:Methyl-1-testosterone 17187:+esterified estrogens 17161:Methandriol diacetate 16826:Mesterolone cipionate 16508:4-Hydroxytestosterone 15787:TATA-binding proteins 11020:Transcription factors 10846:. McGill University. 10113:10.1677/erc.0.0110117 9846:10.1074/jbc.275.1.571 9796:10.1128/mcb.18.9.5128 9592:10.1677/jme.0.0290041 6134:10.1056/NEJMoa1315815 5847:Vitamins and Hormones 5678:10.1083/jcb.200609178 5336:10.1677/jme.0.0270309 4156:10.15347/WJM/2023.003 4004:10.1093/humupd/dmq003 3892:10.1055/s-2006-939565 3573:10.1677/jme.0.0210235 3498:10.1210/edrv-16-3-271 3332:Testicular receptor 4 3326:Testicular receptor 2 2970:ligand binding domain 2926:ligand-binding domain 2849:chlormadinone acetate 2566:Clinical significance 2525:nuclear export signal 2472:constitutive activity 2343: 2310:The AR gene contains 2178:serum response factor 2137:, transport from the 2131:conformational change 1977:Effect on development 1944:progesterone receptor 1897: 1346:prostate gland growth 18089:Potassium canrenoate 17557:Quingestanol acetate 17367:Tetrahydrogestrinone 17255:Metenolone enanthate 17081:5α-Dihydrotrestolone 17076:5α-Dihydronandrolone 17064:Trestolone enanthate 17032:Trenbolone enanthate 16998:Norclostebol acetate 16607:Clostebol propionate 10933:genome location and 10776:10.1093/emboj/cdg585 9461:10.1210/me.2004-0117 8248:10.1128/MCB.01672-07 7923:10.1093/hmg/5.9.1311 6722:10.1210/me.2003-0436 6676:10.1210/me.2003-0189 5995:10.1210/en.2008-0137 5823:10.1210/me.2003-0375 5629:10.1128/MCB.01297-06 5419:10.1093/nar/gkac1158 4986:10.1212/WNL.18.7.671 4929:Journal of Andrology 4641:10.1128/MCB.00289-06 4295:10.1210/er.2007-0019 3856:10.1210/me.2002-0070 3044:CREB-binding protein 2297:trinucleotide repeat 2217:histone deacetylases 2174:DNA-binding proteins 1958:transcription factor 1266:single fertilization 984:beta-catenin binding 811:lateral hypothalamus 787:ventromedial nucleus 633:X C3|X 42.82 cM 594:X chromosome (mouse) 492:X chromosome (human) 69:List of PDB id codes 42:Available structures 18612:Dihydrotestosterone 18607:Dehydroandrosterone 18458:Ralaniten (EPI-002) 18339:Inocoterone acetate 18064:Nomegestrol acetate 17964:Delmadinone acetate 17954:Cyproterone acetate 17899:Abiraterone acetate 17869:7α-Thioprogesterone 17479:Etynodiol diacetate 16683:Testosterone esters 16626:Dehydroandrosterone 16523:11-Ketotestosterone 16282:(0.6) Miscellaneous 15813:High-mobility group 15509:Rel homology region 12499:Testicular receptor 12240:DNA-binding domains 10941:UCSC Genome Browser 10373:1999PNAS...9614724L 10271:2002PNAS...99..661T 8862:1999PNAS...96.5458Y 8803:1998PNAS...95.7379M 8744:1996PNAS...93.5517Y 8114:10.1021/bi00123a026 7360:1998PNAS...95.2122A 7239:10.1677/jme.1.01701 7053:2004PNAS..101..464C 6953:2000PNAS...9711256Y 6478:2001PNAS...98.7200L 6386:10.1530/ERC-13-0545 5946:10.1038/aps.2014.18 5721:(50): 29983–29990. 5570:2005PNAS..102.9802S 5360:Urological Research 5276:1994PNAS...91.1234W 5221:2022Natur.608..199H 5161:2018PLoSO..1395046W 4884:2019NatSR...918577S 4802:1988Sci...240..324C 4747:2004PNAS..10110919F 4698:10.1038/nature12451 4690:2013Natur.500..598Y 4245:10.1093/nar/gkad803 4239:(20): 10992–11009. 4197:10.1530/JOE-12-0238 2928:of the protein. AR 2845:cyproterone acetate 2762:dihydrotestosterone 2656:Cyproterone acetate 2646:Dihydrotestosterone 2616: 2523:A ligand dependent 2241:signal transduction 2221:long non-coding RNA 2135:heat shock proteins 2105:Mechanism of action 1999:urogenital tubercle 1932:dihydrotestosterone 1106:cell-cell signaling 1096:signal transduction 1091:sex differentiation 17449:Dihydroethisterone 17312:Dimethyltrienolone 17272:Methylepitiostanol 17250:Metenolone acetate 17183:Methyltestosterone 17086:19-Norandrosterone 17059:Trestolone acetate 17027:Trenbolone acetate 16971:-nitrosocarbamate) 16860:Stenbolone acetate 16750:Bolazine capronate 16602:Clostebol caproate 15647:p53 p63 p73 family 15220:Heat shock factors 10918:Androgen+Receptors 10326:10.1002/pros.10282 7682:10.1042/BJ20030689 6282:J. Steroid Biochem 6195:Neuroendocrinology 6170:clinicaltrials.gov 6038:(43): 41998–2005. 5372:10.1007/BF00262026 4872:Scientific Reports 3931:(3 Suppl): 23–28. 3813:10.1210/edrv-8-1-1 2966:missense mutations 2954:DNA-binding domain 2787:methyltestosterone 2589: 2484:DNA binding domain 2354: 2237:estrogen receptors 2120:gene transcription 1901: 1516:ENSMUSG00000046532 1069:Biological process 1023:Cellular component 989:POU domain binding 897:Molecular function 749:tail of epididymis 18733:Nuclear receptors 18715: 18714: 18675: 18674: 18645: 18638: 18631: 18624: 18556: 18555: 18079:Osaterone acetate 18039:Megestrol acetate 17904:Allyltestosterone 17680:Acetothiolutamide 17599:Megestrol acetate 17402:Vinyltestosterone 17307:Dimethyldienolone 17126:Ethyltestosterone 17054:Trestolone (MENT) 16986:Nandrolone esters 16967:-(2-chloroethyl)- 16843:Nisterime acetate 16720:3α-Androstanediol 16705:1-Androstenedione 16614:Cloxotestosterone 16597:Clostebol acetate 16518:5-Androstenedione 16464:Androgen receptor 16430: 16429: 16414: 16413: 16410: 16409: 16153: 16152: 16149: 16148: 15482: 15481: 15478: 15477: 14724: 14723: 14364: 14363: 13724: 13723: 13720: 13719: 12712: 12711: 12568:Mineralocorticoid 12224: 12223: 12220: 12219: 11924: 11923: 11037:(1) Basic domains 10032:10.1021/bi011384o 9328:(12): 1986–2000. 7762:10.1002/ijc.20362 6426:10.1021/cr020456u 6336:10.1002/med.21548 6244:Endocrine Reviews 6207:10.1159/000337663 5868:978-0-443-13455-5 5564:(28): 9802–9807. 5462:(13): 7341–7346. 5215:(7921): 199–208. 4923:Brown TR (1995). 4684:(7464): 598–602. 4282:Endocrine Reviews 4075:(13): 3001–3015. 4045:10.1002/jbmr.1713 3964:10.1002/mpo.10340 3801:Endocrine Reviews 3699:978-0-12-709855-5 3651:10.1124/pr.58.4.9 3607:(1–3): d780–800. 3486:Endocrine Reviews 2950:N-terminal domain 2742: 2741: 2289:Kennedy's disease 2176:. One example is 2116:direct regulation 2044:ovarian follicles 1983:5-alpha-reductase 1911:), also known as 1905:androgen receptor 1892: 1891: 1888: 1887: 1883:structure summary 1771: 1770: 1767: 1766: 1740: 1739: 1705: 1704: 1684: 1683: 1634: 1633: 1613: 1612: 1571: 1570: 1552: 1551: 1522: 1521: 1503: 1502: 1477: 1476: 1458: 1457: 1406: 1405: 934:chromatin binding 904:metal ion binding 881: 880: 877: 876: 839: 838: 826: 825: 764: 763: 737:corpus epididymis 662: 661: 561: 560: 388: 387: 384: 383: 52:Ortholog search: 18740: 18663: 18659: 18643: 18636: 18629: 18622: 18567: 18566: 18349:Ketodarolutamide 18329:Hydroxyflutamide 18286:(via metabolite 17655: 17651: 17606:Others/unsorted: 17277:Methylstenbolone 17141:Hydroxystenozole 16700:1-Androstenediol 16498:4-Androstenediol 16485: 16484: 16481: 16477: 16457: 16450: 16443: 16434: 16433: 16254:-related factors 16172: 16171: 16159: 16158: 16060:(4.9) Grainyhead 15502: 15501: 15488: 15487: 15440:(3.6) TEA domain 14730:(3.2) Paired box 14371: 14105: 14099: 13793: 13787: 13780: 13779: 13776: 13770: 13761: 13760: 13749: 13748: 13738:Helix-turn-helix 13730: 13729: 12692: 12672: 12647: 12610: 12580:Estrogen related 12529: 12425: 12273: 12266: 12265: 12254:Nuclear receptor 12247: 12246: 12230: 12229: 11909: 11830: 11763: 11632: 11577: 11386: 11381: 11380: 11045: 11044: 11032: 11031: 11013: 11006: 10999: 10990: 10989: 10886: 10884: 10883: 10877: 10870: 10858: 10856: 10855: 10838: 10836: 10835: 10829: 10818: 10798: 10797: 10787: 10764:The EMBO Journal 10755: 10749: 10748: 10738: 10706: 10700: 10699: 10689: 10665: 10659: 10658: 10648: 10624: 10618: 10617: 10607: 10584:The EMBO Journal 10575: 10569: 10568: 10558: 10534: 10528: 10527: 10517: 10493: 10487: 10486: 10476: 10452: 10446: 10445: 10435: 10426:(18): 15426–31. 10411: 10405: 10404: 10394: 10384: 10352: 10346: 10345: 10309: 10303: 10302: 10292: 10282: 10250: 10244: 10243: 10233: 10209: 10203: 10202: 10173: 10167: 10166: 10156: 10147:(49): 46647–54. 10132: 10126: 10125: 10115: 10091: 10085: 10084: 10074: 10050: 10044: 10043: 10026:(50): 15369–77. 10015: 10009: 10008: 9998: 9989:(46): 43749–56. 9974: 9968: 9967: 9947: 9941: 9940: 9930: 9906: 9900: 9899: 9889: 9880:(21): 21766–73. 9865: 9859: 9858: 9848: 9824: 9818: 9817: 9807: 9775: 9769: 9768: 9758: 9734: 9728: 9727: 9717: 9693: 9687: 9686: 9676: 9652: 9646: 9645: 9635: 9626:(47): 31528–33. 9611: 9605: 9604: 9594: 9570: 9564: 9563: 9553: 9529: 9523: 9522: 9512: 9480: 9474: 9473: 9463: 9439: 9430: 9429: 9419: 9395: 9389: 9388: 9378: 9354: 9348: 9347: 9337: 9313: 9307: 9306: 9296: 9272: 9263: 9262: 9252: 9228: 9222: 9221: 9211: 9202:(18): 15345–53. 9187: 9181: 9180: 9170: 9146: 9140: 9139: 9129: 9120:(27): 20853–60. 9105: 9099: 9098: 9088: 9064: 9058: 9057: 9047: 9023: 9017: 9016: 9006: 8982: 8976: 8975: 8965: 8941: 8935: 8934: 8924: 8900: 8894: 8893: 8883: 8873: 8841: 8835: 8834: 8824: 8814: 8782: 8776: 8775: 8765: 8755: 8723: 8717: 8716: 8706: 8682: 8676: 8675: 8665: 8656:(12): 10226–35. 8641: 8630: 8629: 8619: 8587: 8581: 8580: 8570: 8546: 8540: 8539: 8529: 8497: 8486: 8485: 8475: 8466:(17): 17319–28. 8451: 8442: 8441: 8431: 8399: 8393: 8392: 8382: 8373:(41): 38087–94. 8358: 8352: 8351: 8341: 8317: 8311: 8310: 8300: 8276: 8270: 8269: 8259: 8227: 8221: 8220: 8210: 8178: 8169: 8168: 8132: 8126: 8125: 8096: 8090: 8089: 8079: 8070:(29): 25904–13. 8055: 8046: 8045: 8035: 8026:(31): 32444–52. 8011: 8005: 8004: 7994: 7985:(46): 46087–93. 7970: 7964: 7963: 7942: 7936: 7935: 7925: 7901: 7895: 7894: 7884: 7852: 7846: 7845: 7827: 7798: 7792: 7791: 7773: 7747: 7738: 7732: 7731: 7710: 7704: 7703: 7693: 7676:(Pt 2): 373–83. 7661: 7655: 7654: 7644: 7627:(24): 10529–41. 7612: 7606: 7605: 7595: 7563: 7557: 7556: 7546: 7522: 7516: 7515: 7506:(10): 2297–301. 7495: 7489: 7488: 7478: 7454: 7448: 7447: 7437: 7413: 7407: 7406: 7398: 7392: 7391: 7381: 7371: 7339: 7333: 7332: 7304: 7293: 7292: 7282: 7258: 7252: 7251: 7241: 7217: 7211: 7210: 7173: 7167: 7166: 7156: 7132: 7126: 7125: 7115: 7106:(16): 13442–51. 7091: 7085: 7084: 7074: 7064: 7032: 7026: 7025: 7015: 7006:(28): 17485–94. 6991: 6985: 6984: 6974: 6964: 6947:(21): 11256–61. 6932: 6926: 6925: 6905: 6899: 6898: 6888: 6879:(23): 20702–10. 6864: 6858: 6857: 6847: 6823: 6817: 6816: 6806: 6797:(33): 30828–34. 6782: 6776: 6775: 6765: 6756:(13): 11336–44. 6741: 6735: 6734: 6724: 6715:(10): 2388–401. 6700: 6689: 6688: 6678: 6654: 6641: 6640: 6630: 6606: 6600: 6599: 6589: 6580:(16): 12718–24. 6565: 6559: 6558: 6548: 6516: 6510: 6509: 6499: 6489: 6457: 6448: 6447: 6437: 6414:Chemical Reviews 6405: 6399: 6398: 6388: 6364: 6358: 6357: 6347: 6315: 6306: 6305: 6276: 6270: 6269: 6259: 6235: 6229: 6228: 6218: 6186: 6180: 6179: 6177: 6176: 6162: 6156: 6155: 6145: 6113: 6107: 6106: 6096: 6064: 6058: 6057: 6047: 6023: 6017: 6016: 6006: 5974: 5968: 5967: 5957: 5925: 5919: 5918: 5890: 5881: 5880: 5842: 5836: 5835: 5825: 5816:(9): 2132–2150. 5801: 5792: 5791: 5781: 5771: 5762:(8): 1172–1183. 5747: 5741: 5740: 5730: 5706: 5700: 5699: 5689: 5657: 5651: 5650: 5640: 5623:(5): 1823–1843. 5608: 5602: 5601: 5591: 5581: 5549: 5543: 5542: 5532: 5522: 5498: 5492: 5491: 5481: 5471: 5447: 5441: 5440: 5430: 5398: 5392: 5391: 5355: 5349: 5348: 5338: 5314: 5308: 5307: 5297: 5287: 5255: 5249: 5248: 5204: 5193: 5192: 5182: 5172: 5140: 5134: 5133: 5105: 5096: 5095: 5085: 5061: 5055: 5054: 5044: 5033:10.1172/JCI28773 5012: 5006: 5005: 4969: 4963: 4962: 4944: 4920: 4914: 4913: 4903: 4863: 4857: 4856: 4828: 4822: 4821: 4785: 4779: 4778: 4768: 4758: 4741:(30): 10919–24. 4726: 4720: 4719: 4709: 4669: 4663: 4662: 4652: 4620: 4611: 4610: 4600: 4591:(28): 29436–49. 4576: 4570: 4569: 4559: 4535: 4529: 4528: 4518: 4486: 4480: 4479: 4469: 4437: 4431: 4430: 4420: 4411:(27): 20853–60. 4396: 4390: 4389: 4379: 4355: 4349: 4348: 4338: 4314: 4308: 4307: 4297: 4273: 4267: 4266: 4256: 4224: 4218: 4217: 4199: 4175: 4169: 4168: 4158: 4134: 4128: 4127: 4099: 4093: 4092: 4064: 4058: 4057: 4047: 4023: 4017: 4016: 4006: 3982: 3976: 3975: 3947: 3941: 3940: 3918: 3912: 3911: 3875: 3869: 3868: 3858: 3834: 3825: 3824: 3796: 3790: 3789: 3753: 3747: 3746: 3718: 3712: 3711: 3677: 3671: 3670: 3633: 3627: 3626: 3616: 3592: 3586: 3585: 3575: 3551: 3545: 3544: 3516: 3510: 3509: 3481: 3475: 3474: 3463: 3457: 3456: 3445: 3439: 3429: 3418: 3408: 2912:As a drug target 2733: 2726: 2720: 2717: 2686:Hydroxyflutamide 2630: 2626: 2617: 2610: 2603: 2596: 2588: 2514:intramolecularly 1995:urogenital sinus 1917:nuclear receptor 1831: 1830: 1785: 1773: 1772: 1753: 1752: 1724: 1717: 1700: 1688: 1687: 1679: 1643: 1642: 1639:RefSeq (protein) 1629: 1617: 1616: 1608: 1580: 1579: 1556: 1555: 1533: 1532: 1507: 1506: 1488: 1487: 1462: 1461: 1443: 1442: 1412: 1411: 1256:cellular process 954:androgen binding 939:zinc ion binding 887: 886: 873: 864: 857: 850: 849: 835: 803:lobe of prostate 795:efferent ductule 791:seminal vesicula 775: 773:Top expressed in 768: 767: 753:lactiferous duct 745:caput epididymis 721:seminal vesicula 713: 711:Top expressed in 706: 705: 685: 684: 668: 667: 658: 645: 634: 619: 612: 606: 595: 583: 567: 566: 557: 544: 533: 518: 511: 505: 494: 480: 464: 463: 458: 409: 402: 379: 66: 65: 60: 39: 38: 33: 21: 20: 18748: 18747: 18743: 18742: 18741: 18739: 18738: 18737: 18718: 18717: 18716: 18711: 18671: 18661: 18552: 18274:Cyanonilutamide 18203:Bavdegalutamide 18014:Epitestosterone 17854: 17685:Acetoxolutamide 17653: 17643: 17352:Norethandrolone 17327:Methyldienolone 17131:Fluoxymesterone 16941:Dimethandrolone 16801:Epiandrosterone 16479: 16469: 16461: 16431: 16426: 16406: 16276: 16236: 16205: 16166: 16145: 16095: 16072: 16054: 15804: 15778: 15730: 15633: 15580: 15496: 15474: 15434: 15251: 15211: 14907: 14720: 14369: 14360: 14101: 14100: 14095: 14090: 13789: 13788: 13783: 13772: 13771: 13764: 13743: 13716: 13698: 13611: 13599: 13590: 12805: 12801: 12792: 12721: 12718:(2.2) Other Cys 12708: 12688: 12683: 12668: 12663: 12643: 12638: 12606: 12601: 12536:Steroid hormone 12525: 12520: 12421: 12416: 12280:Thyroid hormone 12269: 12260: 12241: 12216: 12171: 12116: 12014: 11920: 11907: 11905: 11900: 11828: 11823: 11761: 11756: 11627: 11625: 11620: 11575: 11570: 11384: 11365: 11039: 11026: 11017: 10894: 10889: 10881: 10879: 10878:on 6 April 2008 10875: 10868: 10853: 10851: 10833: 10831: 10827: 10816: 10807: 10805:Further reading 10802: 10801: 10770:(22): 6101–14. 10756: 10752: 10707: 10703: 10666: 10662: 10639:(7): 1492–501. 10625: 10621: 10576: 10572: 10549:(27): 19441–6. 10535: 10531: 10502:Cancer Research 10494: 10490: 10467:(32): 22373–9. 10453: 10449: 10412: 10408: 10367:(26): 14724–9. 10353: 10349: 10310: 10306: 10251: 10247: 10210: 10206: 10174: 10170: 10133: 10129: 10092: 10088: 10065:(19): 7156–68. 10059:Cancer Research 10051: 10047: 10016: 10012: 9975: 9971: 9952:Cancer Research 9948: 9944: 9907: 9903: 9866: 9862: 9825: 9821: 9776: 9772: 9735: 9731: 9694: 9690: 9653: 9649: 9612: 9608: 9571: 9567: 9544:(50): 48020–7. 9530: 9526: 9481: 9477: 9454:(10): 2409–23. 9440: 9433: 9410:(33): 30031–9. 9396: 9392: 9355: 9351: 9314: 9310: 9273: 9266: 9229: 9225: 9188: 9184: 9161:(36): 5609–18. 9147: 9143: 9106: 9102: 9065: 9061: 9024: 9020: 8983: 8979: 8956:(10): 1645–56. 8942: 8938: 8901: 8897: 8856:(10): 5458–63. 8842: 8838: 8797:(13): 7379–84. 8783: 8779: 8738:(11): 5517–21. 8724: 8720: 8683: 8679: 8642: 8633: 8602:(12): 1928–36. 8588: 8584: 8547: 8543: 8498: 8489: 8452: 8445: 8414:(12): 8383–92. 8400: 8396: 8359: 8355: 8332:(45): 35200–8. 8318: 8314: 8291:(45): 42852–8. 8277: 8273: 8228: 8224: 8179: 8172: 8133: 8129: 8097: 8093: 8056: 8049: 8012: 8008: 7971: 7967: 7954:(16): 4888–94. 7948:Cancer Research 7943: 7939: 7902: 7898: 7853: 7849: 7810:(8–9): 549–52. 7799: 7795: 7745: 7739: 7735: 7711: 7707: 7662: 7658: 7613: 7609: 7572:Cancer Research 7564: 7560: 7537:(13): 9308–13. 7523: 7519: 7500:Cancer Research 7496: 7492: 7455: 7451: 7414: 7410: 7399: 7395: 7340: 7336: 7305: 7296: 7273:(48): 31853–9. 7259: 7255: 7218: 7214: 7185:(3–4): 285–97. 7174: 7170: 7147:(13): 9978–84. 7133: 7129: 7092: 7088: 7033: 7029: 6992: 6988: 6933: 6929: 6910:Cancer Research 6906: 6902: 6865: 6861: 6838:(36): 5602–13. 6824: 6820: 6783: 6779: 6742: 6738: 6701: 6692: 6655: 6644: 6621:(19): 11660–6. 6607: 6603: 6566: 6562: 6531:(20): 7189–97. 6517: 6513: 6458: 6451: 6406: 6402: 6365: 6361: 6316: 6309: 6277: 6273: 6236: 6232: 6187: 6183: 6174: 6172: 6164: 6163: 6159: 6128:(11): 1028–38. 6114: 6110: 6065: 6061: 6024: 6020: 5975: 5971: 5926: 5922: 5895:Cancer Research 5891: 5884: 5869: 5843: 5839: 5802: 5795: 5748: 5744: 5707: 5703: 5658: 5654: 5609: 5605: 5550: 5546: 5499: 5495: 5448: 5444: 5399: 5395: 5356: 5352: 5315: 5311: 5256: 5252: 5205: 5196: 5155:(3): e0195046. 5141: 5137: 5106: 5099: 5062: 5058: 5027:(10): 2663–72. 5013: 5009: 4970: 4966: 4921: 4917: 4864: 4860: 4829: 4825: 4796:(4850): 324–6. 4786: 4782: 4727: 4723: 4670: 4666: 4635:(21): 8122–35. 4621: 4614: 4577: 4573: 4550:(14): 2011–21. 4536: 4532: 4501:(23): 8563–75. 4487: 4483: 4452:(10): 3373–88. 4438: 4434: 4397: 4393: 4356: 4352: 4323:Cancer Research 4315: 4311: 4274: 4270: 4225: 4221: 4176: 4172: 4135: 4131: 4100: 4096: 4065: 4061: 4038:(12): 2535–43. 4024: 4020: 3983: 3979: 3948: 3944: 3919: 3915: 3876: 3872: 3835: 3828: 3797: 3793: 3754: 3750: 3719: 3715: 3700: 3678: 3674: 3634: 3630: 3593: 3589: 3552: 3548: 3517: 3513: 3482: 3478: 3465: 3464: 3460: 3447: 3446: 3442: 3430: 3421: 3409: 3400: 3395: 3378: 3373: 2978: 2962: 2960:Drug resistance 2918:prostate cancer 2914: 2907:, JN compounds) 2837: 2816: 2766:androstenedione 2747: 2738: 2737: 2736: 2727: 2723: 2718: 2714: 2708: 2628: 2614: 2587: 2579:prostate cancer 2568: 2560:prostate cancer 2545: 2543:Splice variants 2412: 2359: 2338: 2321: 2308: 2293:point mutations 2291:. In addition, 2277: 2267:located on the 2258: 2253: 2229: 2211:-dependent and 2201:prostate cancer 2193:transactivation 2112: 2107: 2076: 2074:Role in females 2060: 1979: 1974: 1788: 1762:View/Edit Mouse 1757:View/Edit Human 1720: 1713: 1710:Location (UCSC) 1696: 1675: 1671: 1665: 1661: 1657: 1653: 1649: 1625: 1604: 1600: 1596: 1592: 1588: 1544: 1497:ENSG00000169083 1390: 1356:spermatogenesis 1064: 1050:plasma membrane 1018: 974:protein binding 959:steroid binding 869: 859: 858: 831: 822: 817: 813: 809: 805: 801: 797: 793: 789: 785: 771: 760: 755: 751: 747: 743: 739: 735: 731: 727: 723: 709: 653: 640: 632: 622: 621: 620: 613: 593: 570:Gene location ( 552: 539: 531: 521: 520: 519: 512: 490: 467:Gene location ( 418: 405: 398: 75: 53: 17: 12: 11: 5: 18746: 18736: 18735: 18730: 18713: 18712: 18710: 18709: 18704: 18699: 18694: 18689: 18684: 18680: 18677: 18676: 18673: 18672: 18670: 18669: 18664: 18654: 18649: 18625:-α-Amino acids 18619: 18614: 18609: 18604: 18573: 18571: 18564: 18558: 18557: 18554: 18553: 18551: 18550: 18545: 18540: 18535: 18530: 18525: 18520: 18515: 18510: 18505: 18500: 18495: 18490: 18485: 18480: 18475: 18470: 18465: 18460: 18455: 18450: 18445: 18440: 18435: 18430: 18425: 18420: 18415: 18410: 18402: 18394: 18386: 18381: 18376: 18371: 18366: 18361: 18356: 18351: 18346: 18341: 18336: 18331: 18326: 18321: 18316: 18311: 18306: 18301: 18296: 18291: 18281: 18276: 18271: 18266: 18261: 18256: 18251: 18246: 18241: 18215: 18210: 18205: 18200: 18195: 18190: 18185: 18180: 18175: 18170: 18165: 18152: 18151: 18146: 18141: 18136: 18131: 18126: 18121: 18119:Spironolactone 18116: 18111: 18106: 18101: 18096: 18091: 18086: 18081: 18076: 18071: 18066: 18061: 18056: 18051: 18046: 18041: 18036: 18031: 18026: 18021: 18016: 18011: 18006: 18001: 17996: 17991: 17986: 17981: 17976: 17971: 17966: 17961: 17956: 17951: 17946: 17944:Cyproheptadine 17941: 17936: 17931: 17926: 17921: 17919:Canrenoic acid 17916: 17911: 17906: 17901: 17896: 17891: 17886: 17881: 17876: 17871: 17862: 17860: 17856: 17855: 17853: 17852: 17847: 17842: 17837: 17828: 17827: 17822: 17817: 17812: 17807: 17802: 17797: 17792: 17787: 17782: 17777: 17772: 17767: 17762: 17757: 17752: 17747: 17742: 17737: 17732: 17727: 17722: 17717: 17712: 17707: 17702: 17697: 17692: 17687: 17682: 17677: 17672: 17667: 17658: 17656: 17645: 17644: 17642: 17641: 17636: 17631: 17626: 17621: 17616: 17611: 17602: 17601: 17596: 17591: 17582: 17581: 17576: 17567: 17566: 17561: 17560: 17559: 17549: 17547:Norgestrienone 17544: 17539: 17525: 17523:Norethisterone 17520: 17519: 17518: 17508: 17498: 17496:Levonorgestrel 17493: 17488: 17483: 17482: 17481: 17471: 17466: 17461: 17452: 17451: 17446: 17441: 17432: 17431: 17426: 17425: 17424: 17414: 17405: 17404: 17395: 17394: 17385: 17384: 17379: 17370: 17369: 17364: 17359: 17354: 17349: 17344: 17339: 17334: 17329: 17324: 17319: 17317:Ethyldienolone 17314: 17309: 17304: 17295: 17294: 17289: 17284: 17279: 17274: 17269: 17264: 17259: 17258: 17257: 17252: 17242: 17237: 17232: 17227: 17222: 17220:Androisoxazole 17213: 17212: 17207: 17202: 17197: 17196: 17195: 17180: 17175: 17174: 17173: 17168: 17163: 17158: 17148: 17143: 17138: 17133: 17128: 17123: 17118: 17113: 17108: 17103: 17098: 17089: 17088: 17083: 17078: 17069: 17068: 17067: 17066: 17061: 17051: 17046: 17045: 17044: 17039: 17034: 17029: 17019: 17018: 17017: 17007: 17002: 17001: 17000: 16990: 16989: 16988: 16978: 16973: 16960: 16959: 16958: 16953: 16948: 16938: 16933: 16928: 16923: 16918: 16917: 16916: 16906: 16901: 16896: 16891: 16890: 16889: 16879: 16870: 16869: 16864: 16863: 16862: 16852: 16847: 16846: 16845: 16835: 16833:Methyldiazinol 16830: 16829: 16828: 16818: 16813: 16808: 16803: 16798: 16797: 16796: 16786: 16785: 16784: 16769: 16764: 16759: 16754: 16753: 16752: 16742: 16737: 16732: 16727: 16722: 16717: 16715:1-Testosterone 16712: 16707: 16702: 16693: 16692: 16691: 16690: 16685: 16670: 16665: 16660: 16655: 16650: 16645: 16644: 16643: 16638: 16628: 16623: 16622: 16621: 16611: 16610: 16609: 16604: 16599: 16589: 16584: 16583: 16582: 16572: 16567: 16562: 16561: 16560: 16555: 16550: 16545: 16535: 16530: 16525: 16520: 16515: 16510: 16505: 16500: 16491: 16489: 16482: 16471: 16470: 16460: 16459: 16452: 16445: 16437: 16428: 16427: 16419: 16416: 16415: 16412: 16411: 16408: 16407: 16405: 16404: 16395: 16394: 16393: 16388: 16383: 16373: 16368: 16367: 16366: 16361: 16356: 16346: 16345: 16344: 16339: 16329: 16324: 16323: 16322: 16317: 16312: 16307: 16302: 16297: 16286: 16284: 16278: 16277: 16275: 16274: 16269: 16264: 16258: 16256: 16238: 16237: 16235: 16234: 16229: 16224: 16218: 16216: 16207: 16206: 16204: 16203: 16198: 16197: 16196: 16191: 16180: 16178: 16168: 16167: 16155: 16154: 16151: 16150: 16147: 16146: 16144: 16143: 16142: 16141: 16136: 16131: 16126: 16121: 16116: 16105: 16103: 16097: 16096: 16094: 16093: 16088: 16082: 16080: 16074: 16073: 16071: 16070: 16064: 16062: 16056: 16055: 16053: 16052: 16051: 16050: 16045: 16040: 16035: 16025: 16024: 16023: 16018: 16017: 16016: 16011: 16006: 15991: 15986: 15981: 15980: 15979: 15974: 15969: 15964: 15959: 15954: 15949: 15944: 15939: 15934: 15929: 15924: 15919: 15914: 15909: 15904: 15894: 15893: 15892: 15887: 15877: 15876: 15875: 15870: 15865: 15860: 15850: 15849: 15848: 15843: 15838: 15833: 15823: 15817: 15815: 15806: 15805: 15803: 15802: 15797: 15791: 15789: 15780: 15779: 15777: 15776: 15771: 15770: 15769: 15764: 15759: 15754: 15743: 15741: 15732: 15731: 15729: 15728: 15723: 15722: 15721: 15716: 15711: 15706: 15701: 15696: 15691: 15686: 15681: 15676: 15666: 15665: 15664: 15659: 15654: 15643: 15641: 15639:(4.3) p53-like 15635: 15634: 15632: 15631: 15630: 15629: 15624: 15619: 15614: 15609: 15604: 15593: 15591: 15582: 15581: 15579: 15578: 15577: 15576: 15571: 15566: 15561: 15556: 15546: 15545: 15544: 15539: 15534: 15529: 15524: 15513: 15511: 15498: 15497: 15484: 15483: 15480: 15479: 15476: 15475: 15473: 15472: 15471: 15470: 15465: 15460: 15455: 15444: 15442: 15436: 15435: 15433: 15432: 15427: 15422: 15421: 15420: 15415: 15410: 15405: 15400: 15395: 15390: 15385: 15375: 15370: 15369: 15368: 15363: 15358: 15353: 15343: 15342: 15341: 15336: 15331: 15326: 15316: 15311: 15310: 15309: 15304: 15299: 15289: 15284: 15283: 15282: 15277: 15272: 15261: 15259: 15253: 15252: 15250: 15249: 15248: 15247: 15242: 15237: 15224: 15222: 15213: 15212: 15210: 15209: 15208: 15207: 15202: 15197: 15192: 15187: 15182: 15177: 15172: 15167: 15162: 15157: 15152: 15147: 15142: 15137: 15132: 15127: 15122: 15117: 15112: 15107: 15102: 15097: 15092: 15087: 15082: 15077: 15072: 15067: 15062: 15057: 15052: 15047: 15042: 15037: 15032: 15027: 15022: 15017: 15012: 15007: 15002: 14997: 14992: 14987: 14982: 14977: 14972: 14967: 14957: 14956: 14955: 14950: 14945: 14940: 14935: 14924: 14922: 14909: 14908: 14906: 14905: 14904: 14903: 14902: 14901: 14896: 14891: 14881: 14880: 14879: 14874: 14864: 14859: 14849: 14844: 14839: 14834: 14829: 14824: 14823: 14822: 14817: 14807: 14802: 14801: 14800: 14795: 14787: 14786: 14785: 14780: 14775: 14770: 14765: 14760: 14755: 14750: 14745: 14734: 14732: 14726: 14725: 14722: 14721: 14719: 14718: 14717: 14716: 14711: 14701: 14696: 14695: 14694: 14689: 14684: 14679: 14674: 14669: 14660: 14655: 14650: 14641: 14631: 14630: 14629: 14624: 14619: 14614: 14609: 14604: 14599: 14594: 14589: 14579: 14578: 14577: 14576: 14575: 14570: 14565: 14560: 14555: 14545: 14544: 14543: 14538: 14528: 14527: 14526: 14521: 14516: 14506: 14505: 14504: 14499: 14489: 14488: 14487: 14482: 14477: 14472: 14467: 14462: 14457: 14444: 14439: 14438: 14437: 14432: 14422: 14417: 14412: 14411: 14410: 14405: 14400: 14390: 14385: 14380: 14374: 14372: 14366: 14365: 14362: 14361: 14359: 14358: 14353: 14348: 14343: 14338: 14333: 14328: 14327: 14326: 14321: 14316: 14311: 14306: 14301: 14296: 14291: 14286: 14281: 14276: 14266: 14261: 14260: 14259: 14254: 14244: 14239: 14234: 14229: 14224: 14223: 14222: 14217: 14207: 14206: 14205: 14200: 14188: 14187: 14186: 14181: 14176: 14171: 14166: 14161: 14151: 14150: 14149: 14144: 14134: 14129: 14124: 14119: 14114: 14108: 14106: 14092: 14091: 14089: 14088: 14083: 14078: 14073: 14072: 14071: 14066: 14061: 14056: 14051: 14046: 14041: 14036: 14031: 14026: 14021: 14016: 14011: 14006: 14001: 13996: 13991: 13986: 13981: 13976: 13971: 13966: 13961: 13956: 13951: 13946: 13941: 13936: 13931: 13926: 13921: 13916: 13911: 13906: 13901: 13896: 13891: 13886: 13876: 13871: 13866: 13861: 13857:extended Hox: 13855: 13854: 13853: 13852: 13851: 13846: 13841: 13831: 13830: 13829: 13819: 13818: 13817: 13812: 13796: 13794: 13777: 13758: 13745: 13744: 13726: 13725: 13722: 13721: 13718: 13717: 13715: 13714: 13708: 13706: 13700: 13699: 13697: 13696: 13691: 13690: 13689: 13684: 13679: 13674: 13669: 13659: 13658: 13657: 13652: 13647: 13637: 13632: 13627: 13621: 13619: 13613: 13612: 13610: 13609: 13603: 13601: 13597: 13592: 13591: 13589: 13588: 13587: 13586: 13581: 13576: 13571: 13566: 13561: 13556: 13551: 13546: 13541: 13536: 13531: 13526: 13521: 13516: 13511: 13506: 13501: 13496: 13491: 13486: 13481: 13476: 13471: 13466: 13461: 13456: 13451: 13446: 13441: 13436: 13431: 13426: 13421: 13416: 13411: 13406: 13401: 13396: 13391: 13386: 13381: 13376: 13371: 13366: 13361: 13351: 13350: 13349: 13344: 13339: 13334: 13329: 13324: 13319: 13314: 13304: 13303: 13302: 13297: 13287: 13282: 13277: 13276: 13275: 13270: 13265: 13260: 13250: 13245: 13240: 13235: 13230: 13229: 13228: 13227: 13226: 13221: 13216: 13211: 13206: 13196: 13195: 13194: 13189: 13184: 13179: 13174: 13169: 13164: 13159: 13154: 13149: 13144: 13139: 13134: 13129: 13124: 13119: 13104: 13103: 13102: 13097: 13087: 13086: 13085: 13080: 13075: 13065: 13064: 13063: 13058: 13053: 13043: 13042: 13041: 13036: 13026: 13025: 13024: 13019: 13014: 13009: 13004: 12999: 12994: 12984: 12979: 12974: 12973: 12972: 12967: 12962: 12957: 12947: 12942: 12937: 12936: 12935: 12930: 12925: 12913: 12907: 12906: 12905: 12904: 12903: 12902: 12897: 12892: 12887: 12882: 12877: 12872: 12867: 12857: 12852: 12847: 12846: 12845: 12840: 12830: 12825: 12820: 12809: 12807: 12803: 12799: 12794: 12793: 12791: 12790: 12785: 12784: 12783: 12778: 12773: 12763: 12762: 12761: 12756: 12751: 12746: 12741: 12736: 12725: 12723: 12719: 12714: 12713: 12710: 12709: 12707: 12706: 12701: 12695: 12693: 12685: 12684: 12682: 12681: 12675: 12673: 12665: 12664: 12662: 12661: 12656: 12650: 12648: 12640: 12639: 12637: 12636: 12635: 12634: 12629: 12624: 12613: 12611: 12603: 12602: 12600: 12599: 12598: 12597: 12592: 12587: 12577: 12576: 12575: 12570: 12565: 12563:Glucocorticoid 12560: 12559: 12558: 12553: 12543: 12532: 12530: 12522: 12521: 12519: 12518: 12513: 12512: 12511: 12506: 12496: 12495: 12494: 12489: 12484: 12474: 12469: 12468: 12467: 12462: 12452: 12447: 12446: 12445: 12440: 12428: 12426: 12418: 12417: 12415: 12414: 12409: 12408: 12407: 12402: 12392: 12391: 12390: 12385: 12380: 12370: 12369: 12368: 12363: 12358: 12348: 12343: 12342: 12341: 12336: 12331: 12321: 12320: 12319: 12314: 12304: 12299: 12294: 12293: 12292: 12287: 12276: 12274: 12263: 12258: 12243: 12242: 12226: 12225: 12222: 12221: 12218: 12217: 12215: 12214: 12213: 12212: 12207: 12202: 12197: 12192: 12181: 12179: 12173: 12172: 12170: 12169: 12168: 12167: 12162: 12157: 12152: 12147: 12142: 12137: 12126: 12124: 12118: 12117: 12115: 12114: 12113: 12112: 12106: 12105: 12104: 12099: 12089: 12088: 12087: 12082: 12077: 12072: 12067: 12052: 12051: 12050: 12045: 12040: 12035: 12024: 12022: 12016: 12015: 12013: 12012: 12007: 12006: 12005: 12000: 11990: 11985: 11980: 11975: 11970: 11965: 11960: 11959: 11958: 11953: 11943: 11937: 11935: 11926: 11925: 11922: 11921: 11919: 11918: 11912: 11910: 11902: 11901: 11899: 11898: 11897: 11896: 11891: 11886: 11876: 11875: 11874: 11869: 11864: 11859: 11854: 11849: 11844: 11833: 11831: 11825: 11824: 11822: 11821: 11820: 11819: 11814: 11809: 11804: 11794: 11789: 11788: 11787: 11782: 11777: 11766: 11764: 11758: 11757: 11755: 11754: 11753: 11752: 11747: 11737: 11736: 11735: 11730: 11725: 11720: 11710: 11709: 11708: 11703: 11698: 11690: 11689: 11688: 11683: 11678: 11668: 11663: 11662: 11661: 11656: 11646: 11641: 11635: 11633: 11622: 11621: 11619: 11618: 11613: 11608: 11607: 11606: 11601: 11596: 11586: 11580: 11578: 11572: 11571: 11569: 11568: 11563: 11562: 11561: 11560: 11559: 11554: 11544: 11534: 11533: 11532: 11527: 11517: 11516: 11515: 11510: 11500: 11499: 11498: 11493: 11488: 11478: 11477: 11476: 11471: 11461: 11460: 11459: 11454: 11449: 11444: 11434: 11429: 11428: 11427: 11422: 11412: 11407: 11406: 11405: 11400: 11389: 11387: 11378: 11367: 11366: 11364: 11363: 11358: 11357: 11356: 11351: 11346: 11336: 11331: 11326: 11325: 11324: 11319: 11314: 11309: 11299: 11298: 11297: 11292: 11287: 11282: 11272: 11267: 11262: 11257: 11252: 11247: 11242: 11241: 11240: 11235: 11230: 11220: 11219: 11218: 11213: 11208: 11203: 11198: 11193: 11183: 11178: 11173: 11172: 11171: 11166: 11156: 11155: 11154: 11149: 11144: 11139: 11134: 11129: 11124: 11119: 11109: 11108: 11107: 11102: 11097: 11092: 11087: 11082: 11077: 11072: 11061: 11059: 11052:leucine zipper 11041: 11040: 11028: 11027: 11016: 11015: 11008: 11001: 10993: 10987: 10986: 10965: 10944: 10925: 10915: 10910: 10905: 10900: 10893: 10892:External links 10890: 10888: 10887: 10859: 10839: 10808: 10806: 10803: 10800: 10799: 10750: 10701: 10660: 10619: 10570: 10529: 10508:(9): 3486–94. 10488: 10447: 10406: 10347: 10304: 10245: 10224:(9): 7076–85. 10204: 10168: 10127: 10086: 10045: 10010: 9969: 9942: 9901: 9860: 9819: 9790:(9): 5128–39. 9770: 9749:(13): 8570–6. 9729: 9708:(7): 4609–17. 9688: 9647: 9606: 9565: 9524: 9495:(5): 2202–13. 9475: 9431: 9390: 9349: 9308: 9264: 9223: 9182: 9141: 9100: 9059: 9038:(7): 5052–61. 9018: 8977: 8936: 8915:(2): 287–300. 8895: 8836: 8777: 8718: 8677: 8631: 8582: 8561:(9): 3440–50. 8541: 8512:(6): 2135–50. 8487: 8443: 8394: 8353: 8312: 8271: 8242:(6): 1947–63. 8222: 8193:(4): 1238–57. 8170: 8127: 8091: 8047: 8006: 7965: 7937: 7896: 7847: 7793: 7733: 7705: 7656: 7607: 7578:(8): 3347–55. 7558: 7517: 7490: 7449: 7428:(5): 797–811. 7408: 7393: 7334: 7294: 7253: 7212: 7168: 7127: 7086: 7027: 6986: 6927: 6916:(21): 5946–9. 6900: 6859: 6818: 6777: 6736: 6690: 6642: 6601: 6560: 6511: 6472:(13): 7200–5. 6449: 6420:(9): 3352–70. 6400: 6379:(4): T105–18. 6359: 6330:(3): 910–960. 6307: 6271: 6250:(2): 175–200. 6230: 6181: 6157: 6108: 6059: 6018: 5969: 5920: 5901:(1): 543–553. 5882: 5867: 5837: 5793: 5742: 5701: 5652: 5603: 5544: 5493: 5442: 5393: 5350: 5309: 5250: 5194: 5135: 5097: 5056: 5007: 4964: 4935:(4): 299–303. 4915: 4858: 4823: 4780: 4721: 4664: 4612: 4571: 4530: 4481: 4432: 4391: 4370:(9): 7786–92. 4350: 4329:(5): 1849–57. 4309: 4288:(7): 778–808. 4268: 4219: 4190:(2): 221–237. 4170: 4129: 4110:(2): 142–148. 4094: 4059: 4018: 3977: 3942: 3913: 3870: 3849:(10): 2181–7. 3826: 3791: 3748: 3713: 3698: 3672: 3628: 3587: 3546: 3511: 3492:(3): 271–321. 3476: 3458: 3440: 3419: 3397: 3396: 3394: 3391: 3390: 3389: 3384: 3377: 3374: 3372: 3371: 3365: 3359: 3353: 3347: 3341: 3335: 3329: 3323: 3317: 3311: 3305: 3299: 3293: 3287: 3281: 3275: 3269: 3263: 3257: 3251: 3245: 3239: 3233: 3227: 3221: 3215: 3209: 3203: 3197: 3191: 3185: 3179: 3173: 3167: 3161: 3155: 3149: 3143: 3137: 3131: 3125: 3119: 3113: 3107: 3101: 3095: 3089: 3083: 3077: 3071: 3065: 3059: 3053: 3047: 3041: 3035: 3029: 3023: 3017: 3011: 3005: 2999: 2993: 2986: 2977: 2974: 2961: 2958: 2913: 2910: 2909: 2908: 2890: 2860: 2853:spironolactone 2836: 2833: 2832: 2831: 2815: 2812: 2811: 2810: 2777: 2770:androstenediol 2746: 2743: 2740: 2739: 2735: 2734: 2721: 2711: 2710: 2709: 2702: 2701: 2698: 2692: 2691: 2688: 2682: 2681: 2678: 2672: 2671: 2668: 2662: 2661: 2658: 2652: 2651: 2648: 2642: 2641: 2638: 2632: 2631: 2621: 2613: 2612: 2605: 2598: 2590: 2586: 2583: 2567: 2564: 2558:of metastatic 2552:splice variant 2544: 2541: 2540: 2539: 2529: 2528: 2527: 2521: 2510: 2501: 2492: 2491: 2490: 2477: 2476: 2475: 2464: 2457: 2454: 2453: 2452: 2411: 2408: 2407: 2406: 2400: 2358: 2355: 2337: 2334: 2320: 2317: 2307: 2304: 2276: 2273: 2257: 2254: 2252: 2249: 2228: 2225: 2111: 2108: 2106: 2103: 2075: 2072: 2059: 2056: 2052:neuroendocrine 2024:of androgens. 2003:hair follicles 1978: 1975: 1973: 1970: 1890: 1889: 1886: 1885: 1880: 1874: 1873: 1860: 1854: 1853: 1843: 1836: 1835: 1827: 1826: 1821: 1815: 1814: 1809: 1803: 1802: 1801:Androgen_recep 1799: 1795: 1794: 1790: 1789: 1786: 1778: 1777: 1776:Androgen_recep 1769: 1768: 1765: 1764: 1759: 1749: 1748: 1742: 1741: 1738: 1737: 1735: 1733: 1726: 1725: 1718: 1711: 1707: 1706: 1703: 1702: 1692: 1691: 1685: 1682: 1681: 1677:NP_001011645.1 1667: 1666: 1640: 1636: 1635: 1632: 1631: 1621: 1620: 1614: 1611: 1610: 1584: 1583: 1577: 1573: 1572: 1569: 1568: 1560: 1559: 1553: 1550: 1549: 1537: 1536: 1530: 1524: 1523: 1520: 1519: 1511: 1510: 1504: 1501: 1500: 1492: 1491: 1485: 1479: 1478: 1475: 1474: 1466: 1465: 1459: 1456: 1455: 1447: 1446: 1440: 1434: 1433: 1428: 1423: 1419: 1418: 1408: 1407: 1404: 1403: 1392: 1391: 1389: 1388: 1383: 1378: 1373: 1368: 1363: 1358: 1353: 1348: 1343: 1338: 1333: 1328: 1323: 1318: 1313: 1308: 1303: 1298: 1293: 1288: 1283: 1278: 1273: 1268: 1263: 1258: 1253: 1248: 1243: 1238: 1233: 1228: 1223: 1218: 1213: 1208: 1203: 1198: 1193: 1188: 1183: 1178: 1173: 1168: 1163: 1158: 1153: 1148: 1143: 1138: 1133: 1128: 1123: 1118: 1113: 1108: 1103: 1098: 1093: 1088: 1083: 1078: 1072: 1070: 1066: 1065: 1063: 1062: 1057: 1052: 1047: 1042: 1037: 1032: 1026: 1024: 1020: 1019: 1017: 1016: 1011: 1006: 1001: 996: 994:enzyme binding 991: 986: 981: 976: 971: 966: 961: 956: 951: 949:ATPase binding 946: 941: 936: 931: 926: 921: 916: 911: 906: 900: 898: 894: 893: 883: 882: 879: 878: 875: 874: 866: 865: 847: 841: 840: 837: 836: 828: 827: 824: 823: 821: 820: 816: 812: 808: 804: 800: 796: 792: 788: 784: 783:lacrimal gland 780: 777: 776: 765: 762: 761: 759: 758: 754: 750: 746: 742: 738: 734: 730: 726: 722: 718: 715: 714: 702: 701: 693: 682: 676: 675: 672:RNA expression 664: 663: 660: 659: 651: 647: 646: 638: 635: 630: 624: 623: 614: 607: 601: 597: 596: 591: 585: 584: 576: 575: 563: 562: 559: 558: 550: 546: 545: 537: 534: 529: 523: 522: 513: 506: 500: 496: 495: 488: 482: 481: 473: 472: 460: 459: 456:AR - orthologs 416: 412: 411: 403: 395: 394: 390: 389: 386: 385: 382: 381: 71: 70: 62: 61: 50: 44: 43: 35: 34: 26: 25: 15: 9: 6: 4: 3: 2: 18745: 18734: 18731: 18729: 18726: 18725: 18723: 18708: 18705: 18703: 18700: 18698: 18695: 18693: 18690: 18688: 18685: 18682: 18681: 18678: 18668: 18665: 18660: 18655: 18653: 18650: 18647: 18640: 18633: 18626: 18620: 18618: 18615: 18613: 18610: 18608: 18605: 18602: 18598: 18594: 18590: 18586: 18582: 18578: 18575: 18574: 18572: 18568: 18565: 18563: 18559: 18549: 18546: 18544: 18541: 18539: 18536: 18534: 18531: 18529: 18528:Valproic acid 18526: 18524: 18521: 18519: 18516: 18514: 18511: 18509: 18506: 18504: 18501: 18499: 18496: 18494: 18491: 18489: 18486: 18484: 18481: 18479: 18476: 18474: 18473:Rezvilutamide 18471: 18469: 18466: 18464: 18461: 18459: 18456: 18454: 18451: 18449: 18448:Proxalutamide 18446: 18444: 18441: 18439: 18436: 18434: 18431: 18429: 18426: 18424: 18421: 18419: 18416: 18414: 18411: 18409: 18407: 18403: 18401: 18399: 18395: 18393: 18391: 18387: 18385: 18382: 18380: 18377: 18375: 18372: 18370: 18367: 18365: 18362: 18360: 18357: 18355: 18352: 18350: 18347: 18345: 18342: 18340: 18337: 18335: 18332: 18330: 18327: 18325: 18322: 18320: 18317: 18315: 18312: 18310: 18307: 18305: 18302: 18300: 18297: 18295: 18292: 18289: 18285: 18282: 18280: 18277: 18275: 18272: 18270: 18267: 18265: 18262: 18260: 18257: 18255: 18252: 18250: 18247: 18245: 18242: 18239: 18235: 18231: 18227: 18223: 18219: 18216: 18214: 18211: 18209: 18206: 18204: 18201: 18199: 18196: 18194: 18191: 18189: 18186: 18184: 18181: 18179: 18176: 18174: 18171: 18169: 18166: 18164: 18163:-Bicalutamide 18162: 18157: 18156:Nonsteroidal: 18154: 18153: 18150: 18147: 18145: 18142: 18140: 18137: 18135: 18132: 18130: 18127: 18125: 18122: 18120: 18117: 18115: 18112: 18110: 18107: 18105: 18102: 18100: 18097: 18095: 18092: 18090: 18087: 18085: 18082: 18080: 18077: 18075: 18072: 18070: 18067: 18065: 18062: 18060: 18057: 18055: 18052: 18050: 18047: 18045: 18042: 18040: 18037: 18035: 18032: 18030: 18027: 18025: 18024:Guggulsterone 18022: 18020: 18017: 18015: 18012: 18010: 18007: 18005: 18002: 18000: 17997: 17995: 17992: 17990: 17987: 17985: 17982: 17980: 17977: 17975: 17972: 17970: 17967: 17965: 17962: 17960: 17957: 17955: 17952: 17950: 17947: 17945: 17942: 17940: 17937: 17935: 17932: 17930: 17927: 17925: 17922: 17920: 17917: 17915: 17912: 17910: 17907: 17905: 17902: 17900: 17897: 17895: 17892: 17890: 17887: 17885: 17882: 17880: 17877: 17875: 17872: 17870: 17867: 17864: 17863: 17861: 17857: 17851: 17848: 17846: 17843: 17841: 17838: 17836: 17833: 17830: 17829: 17826: 17823: 17821: 17818: 17816: 17813: 17811: 17808: 17806: 17803: 17801: 17798: 17796: 17793: 17791: 17788: 17786: 17783: 17781: 17778: 17776: 17773: 17771: 17768: 17766: 17763: 17761: 17758: 17756: 17753: 17751: 17748: 17746: 17743: 17741: 17738: 17736: 17733: 17731: 17728: 17726: 17723: 17721: 17718: 17716: 17713: 17711: 17708: 17706: 17703: 17701: 17698: 17696: 17693: 17691: 17688: 17686: 17683: 17681: 17678: 17676: 17673: 17671: 17668: 17666: 17663: 17662:Nonsteroidal: 17660: 17659: 17657: 17652: 17646: 17640: 17637: 17635: 17632: 17630: 17627: 17625: 17622: 17620: 17617: 17615: 17614:5α-Androstane 17612: 17610: 17607: 17604: 17603: 17600: 17597: 17595: 17592: 17590: 17587: 17584: 17583: 17580: 17577: 17575: 17572: 17569: 17568: 17565: 17562: 17558: 17555: 17554: 17553: 17550: 17548: 17545: 17543: 17540: 17537: 17533: 17529: 17526: 17524: 17521: 17517: 17514: 17513: 17512: 17509: 17506: 17502: 17499: 17497: 17494: 17492: 17489: 17487: 17484: 17480: 17477: 17476: 17475: 17472: 17470: 17467: 17465: 17462: 17460: 17457: 17454: 17453: 17450: 17447: 17445: 17442: 17440: 17437: 17434: 17433: 17430: 17427: 17423: 17422:Ethandrostate 17420: 17419: 17418: 17415: 17413: 17410: 17407: 17406: 17403: 17400: 17397: 17396: 17393: 17390: 17387: 17386: 17383: 17380: 17378: 17375: 17372: 17371: 17368: 17365: 17363: 17360: 17358: 17355: 17353: 17350: 17348: 17345: 17343: 17340: 17338: 17335: 17333: 17330: 17328: 17325: 17323: 17322:Ethylestrenol 17320: 17318: 17315: 17313: 17310: 17308: 17305: 17303: 17300: 17297: 17296: 17293: 17290: 17288: 17285: 17283: 17280: 17278: 17275: 17273: 17270: 17268: 17265: 17263: 17260: 17256: 17253: 17251: 17248: 17247: 17246: 17243: 17241: 17238: 17236: 17233: 17231: 17228: 17226: 17223: 17221: 17218: 17215: 17214: 17211: 17208: 17206: 17203: 17201: 17198: 17194: 17191: 17190: 17188: 17184: 17181: 17179: 17176: 17172: 17169: 17167: 17164: 17162: 17159: 17157: 17154: 17153: 17152: 17149: 17147: 17144: 17142: 17139: 17137: 17134: 17132: 17129: 17127: 17124: 17122: 17119: 17117: 17114: 17112: 17109: 17107: 17104: 17102: 17099: 17097: 17094: 17091: 17090: 17087: 17084: 17082: 17079: 17077: 17074: 17071: 17070: 17065: 17062: 17060: 17057: 17056: 17055: 17052: 17050: 17047: 17043: 17040: 17038: 17035: 17033: 17030: 17028: 17025: 17024: 17023: 17020: 17016: 17013: 17012: 17011: 17008: 17006: 17003: 16999: 16996: 16995: 16994: 16991: 16987: 16984: 16983: 16982: 16979: 16977: 16974: 16972: 16970: 16966: 16961: 16957: 16954: 16952: 16949: 16947: 16944: 16943: 16942: 16939: 16937: 16934: 16932: 16929: 16927: 16924: 16922: 16919: 16915: 16912: 16911: 16910: 16907: 16905: 16902: 16900: 16897: 16895: 16892: 16888: 16885: 16884: 16883: 16880: 16878: 16875: 16872: 16871: 16868: 16865: 16861: 16858: 16857: 16856: 16853: 16851: 16848: 16844: 16841: 16840: 16839: 16836: 16834: 16831: 16827: 16824: 16823: 16822: 16819: 16817: 16814: 16812: 16809: 16807: 16804: 16802: 16799: 16795: 16792: 16791: 16790: 16787: 16783: 16780: 16779: 16777: 16773: 16770: 16768: 16765: 16763: 16760: 16758: 16755: 16751: 16748: 16747: 16746: 16743: 16741: 16738: 16736: 16733: 16731: 16728: 16726: 16723: 16721: 16718: 16716: 16713: 16711: 16708: 16706: 16703: 16701: 16698: 16695: 16694: 16689: 16686: 16684: 16681: 16680: 16678: 16674: 16671: 16669: 16666: 16664: 16661: 16659: 16656: 16654: 16651: 16649: 16646: 16642: 16639: 16637: 16634: 16633: 16632: 16629: 16627: 16624: 16620: 16617: 16616: 16615: 16612: 16608: 16605: 16603: 16600: 16598: 16595: 16594: 16593: 16590: 16588: 16585: 16581: 16578: 16577: 16576: 16573: 16571: 16568: 16566: 16563: 16559: 16556: 16554: 16551: 16549: 16546: 16544: 16541: 16540: 16539: 16536: 16534: 16531: 16529: 16526: 16524: 16521: 16519: 16516: 16514: 16511: 16509: 16506: 16504: 16501: 16499: 16496: 16493: 16492: 16490: 16486: 16483: 16478: 16472: 16468: 16465: 16458: 16453: 16451: 16446: 16444: 16439: 16438: 16435: 16425: 16424: 16417: 16403: 16399: 16396: 16392: 16389: 16387: 16384: 16382: 16379: 16378: 16377: 16374: 16372: 16369: 16365: 16362: 16360: 16357: 16355: 16352: 16351: 16350: 16347: 16343: 16340: 16338: 16335: 16334: 16333: 16330: 16328: 16325: 16321: 16318: 16316: 16313: 16311: 16308: 16306: 16303: 16301: 16298: 16296: 16293: 16292: 16291: 16288: 16287: 16285: 16283: 16279: 16273: 16270: 16268: 16265: 16263: 16260: 16259: 16257: 16255: 16252: 16249: 16246: 16243: 16239: 16233: 16230: 16228: 16225: 16223: 16220: 16219: 16217: 16215: 16214:Pocket domain 16212: 16208: 16202: 16199: 16195: 16192: 16190: 16187: 16186: 16185: 16182: 16181: 16179: 16177: 16176:(0.2) HMGI(Y) 16173: 16169: 16165: 16160: 16156: 16140: 16137: 16135: 16132: 16130: 16127: 16125: 16122: 16120: 16117: 16115: 16112: 16111: 16110: 16107: 16106: 16104: 16102: 16098: 16092: 16089: 16087: 16084: 16083: 16081: 16079: 16075: 16069: 16066: 16065: 16063: 16061: 16057: 16049: 16046: 16044: 16041: 16039: 16036: 16034: 16031: 16030: 16029: 16026: 16022: 16019: 16015: 16012: 16010: 16007: 16005: 16002: 16001: 16000: 15997: 15996: 15995: 15992: 15990: 15987: 15985: 15982: 15978: 15975: 15973: 15970: 15968: 15965: 15963: 15960: 15958: 15955: 15953: 15950: 15948: 15945: 15943: 15940: 15938: 15935: 15933: 15930: 15928: 15925: 15923: 15920: 15918: 15915: 15913: 15910: 15908: 15905: 15903: 15900: 15899: 15898: 15895: 15891: 15888: 15886: 15883: 15882: 15881: 15878: 15874: 15871: 15869: 15866: 15864: 15861: 15859: 15856: 15855: 15854: 15851: 15847: 15844: 15842: 15839: 15837: 15834: 15832: 15829: 15828: 15827: 15824: 15822: 15819: 15818: 15816: 15814: 15811: 15807: 15801: 15798: 15796: 15793: 15792: 15790: 15788: 15785: 15781: 15775: 15772: 15768: 15765: 15763: 15760: 15758: 15755: 15753: 15750: 15749: 15748: 15745: 15744: 15742: 15740: 15737: 15733: 15727: 15724: 15720: 15717: 15715: 15712: 15710: 15707: 15705: 15702: 15700: 15697: 15695: 15692: 15690: 15687: 15685: 15682: 15680: 15677: 15675: 15672: 15671: 15670: 15667: 15663: 15660: 15658: 15655: 15653: 15650: 15649: 15648: 15645: 15644: 15642: 15640: 15636: 15628: 15625: 15623: 15620: 15618: 15615: 15613: 15610: 15608: 15605: 15603: 15600: 15599: 15598: 15595: 15594: 15592: 15590: 15587: 15583: 15575: 15572: 15570: 15567: 15565: 15562: 15560: 15557: 15555: 15552: 15551: 15550: 15547: 15543: 15540: 15538: 15535: 15533: 15530: 15528: 15525: 15523: 15520: 15519: 15518: 15515: 15514: 15512: 15510: 15507: 15503: 15499: 15495: 15489: 15485: 15469: 15466: 15464: 15461: 15459: 15456: 15454: 15451: 15450: 15449: 15446: 15445: 15443: 15441: 15437: 15431: 15428: 15426: 15423: 15419: 15416: 15414: 15411: 15409: 15406: 15404: 15401: 15399: 15396: 15394: 15391: 15389: 15386: 15384: 15381: 15380: 15379: 15376: 15374: 15371: 15367: 15364: 15362: 15359: 15357: 15354: 15352: 15349: 15348: 15347: 15344: 15340: 15337: 15335: 15332: 15330: 15327: 15325: 15322: 15321: 15320: 15317: 15315: 15312: 15308: 15305: 15303: 15300: 15298: 15295: 15294: 15293: 15290: 15288: 15285: 15281: 15278: 15276: 15273: 15271: 15268: 15267: 15266: 15263: 15262: 15260: 15258: 15254: 15246: 15243: 15241: 15238: 15236: 15233: 15232: 15231: 15230: 15226: 15225: 15223: 15221: 15218: 15214: 15206: 15203: 15201: 15198: 15196: 15193: 15191: 15188: 15186: 15183: 15181: 15178: 15176: 15173: 15171: 15168: 15166: 15163: 15161: 15158: 15156: 15153: 15151: 15148: 15146: 15143: 15141: 15138: 15136: 15133: 15131: 15128: 15126: 15123: 15121: 15118: 15116: 15113: 15111: 15108: 15106: 15103: 15101: 15098: 15096: 15093: 15091: 15088: 15086: 15083: 15081: 15078: 15076: 15073: 15071: 15068: 15066: 15063: 15061: 15058: 15056: 15053: 15051: 15048: 15046: 15043: 15041: 15038: 15036: 15033: 15031: 15028: 15026: 15023: 15021: 15018: 15016: 15013: 15011: 15008: 15006: 15003: 15001: 14998: 14996: 14993: 14991: 14988: 14986: 14983: 14981: 14978: 14976: 14973: 14971: 14968: 14966: 14963: 14962: 14961: 14958: 14954: 14951: 14949: 14946: 14944: 14941: 14939: 14936: 14934: 14931: 14930: 14929: 14926: 14925: 14923: 14921: 14917: 14914: 14910: 14900: 14897: 14895: 14892: 14890: 14887: 14886: 14885: 14882: 14878: 14875: 14873: 14870: 14869: 14868: 14865: 14863: 14860: 14858: 14855: 14854: 14853: 14850: 14848: 14845: 14843: 14840: 14838: 14835: 14833: 14830: 14828: 14825: 14821: 14818: 14816: 14813: 14812: 14811: 14808: 14806: 14803: 14799: 14796: 14794: 14791: 14790: 14788: 14784: 14781: 14779: 14776: 14774: 14771: 14769: 14766: 14764: 14761: 14759: 14756: 14754: 14751: 14749: 14746: 14744: 14741: 14740: 14739: 14736: 14735: 14733: 14731: 14727: 14715: 14712: 14710: 14707: 14706: 14705: 14702: 14700: 14697: 14693: 14690: 14688: 14685: 14683: 14680: 14678: 14675: 14673: 14670: 14668: 14664: 14661: 14659: 14656: 14654: 14651: 14649: 14645: 14642: 14640: 14637: 14636: 14635: 14632: 14628: 14625: 14623: 14620: 14618: 14615: 14613: 14610: 14608: 14605: 14603: 14600: 14598: 14595: 14593: 14590: 14588: 14585: 14584: 14583: 14580: 14574: 14571: 14569: 14566: 14564: 14561: 14559: 14556: 14554: 14551: 14550: 14549: 14546: 14542: 14539: 14537: 14534: 14533: 14532: 14529: 14525: 14522: 14520: 14517: 14515: 14512: 14511: 14510: 14507: 14503: 14500: 14498: 14495: 14494: 14493: 14490: 14486: 14483: 14481: 14478: 14476: 14473: 14471: 14468: 14466: 14463: 14461: 14458: 14456: 14453: 14452: 14451: 14448: 14447: 14445: 14443: 14440: 14436: 14433: 14431: 14428: 14427: 14426: 14423: 14421: 14418: 14416: 14413: 14409: 14406: 14404: 14401: 14399: 14396: 14395: 14394: 14391: 14389: 14386: 14384: 14381: 14379: 14376: 14375: 14373: 14367: 14357: 14354: 14352: 14349: 14347: 14344: 14342: 14339: 14337: 14334: 14332: 14329: 14325: 14322: 14320: 14317: 14315: 14312: 14310: 14307: 14305: 14302: 14300: 14297: 14295: 14292: 14290: 14287: 14285: 14282: 14280: 14277: 14275: 14272: 14271: 14270: 14267: 14265: 14262: 14258: 14255: 14253: 14250: 14249: 14248: 14245: 14243: 14240: 14238: 14235: 14233: 14230: 14228: 14225: 14221: 14218: 14216: 14213: 14212: 14211: 14208: 14204: 14201: 14199: 14196: 14195: 14194: 14193: 14189: 14185: 14182: 14180: 14177: 14175: 14172: 14170: 14167: 14165: 14162: 14160: 14157: 14156: 14155: 14152: 14148: 14145: 14143: 14140: 14139: 14138: 14135: 14133: 14130: 14128: 14125: 14123: 14120: 14118: 14115: 14113: 14110: 14109: 14107: 14104: 14098: 14093: 14087: 14084: 14082: 14079: 14077: 14074: 14070: 14067: 14065: 14062: 14060: 14057: 14055: 14052: 14050: 14047: 14045: 14042: 14040: 14037: 14035: 14032: 14030: 14027: 14025: 14022: 14020: 14017: 14015: 14012: 14010: 14007: 14005: 14002: 14000: 13997: 13995: 13992: 13990: 13987: 13985: 13982: 13980: 13977: 13975: 13972: 13970: 13967: 13965: 13962: 13960: 13957: 13955: 13952: 13950: 13947: 13945: 13942: 13940: 13937: 13935: 13932: 13930: 13927: 13925: 13922: 13920: 13917: 13915: 13912: 13910: 13907: 13905: 13902: 13900: 13897: 13895: 13892: 13890: 13887: 13885: 13882: 13881: 13880: 13877: 13875: 13872: 13870: 13867: 13865: 13862: 13860: 13856: 13850: 13847: 13845: 13842: 13840: 13837: 13836: 13835: 13832: 13828: 13825: 13824: 13823: 13820: 13816: 13813: 13811: 13808: 13807: 13806: 13803: 13802: 13801: 13798: 13797: 13795: 13792: 13786: 13781: 13778: 13775: 13769: 13768: 13762: 13759: 13757: 13754: 13750: 13746: 13742: 13739: 13736: 13731: 13727: 13713: 13710: 13709: 13707: 13705: 13701: 13695: 13692: 13688: 13685: 13683: 13680: 13678: 13675: 13673: 13670: 13668: 13665: 13664: 13663: 13660: 13656: 13653: 13651: 13648: 13646: 13643: 13642: 13641: 13638: 13636: 13633: 13631: 13628: 13626: 13623: 13622: 13620: 13618: 13614: 13608: 13605: 13604: 13602: 13600: 13593: 13585: 13582: 13580: 13577: 13575: 13572: 13570: 13567: 13565: 13562: 13560: 13557: 13555: 13552: 13550: 13547: 13545: 13542: 13540: 13537: 13535: 13532: 13530: 13527: 13525: 13522: 13520: 13517: 13515: 13512: 13510: 13507: 13505: 13502: 13500: 13497: 13495: 13492: 13490: 13487: 13485: 13482: 13480: 13477: 13475: 13472: 13470: 13467: 13465: 13462: 13460: 13457: 13455: 13452: 13450: 13447: 13445: 13442: 13440: 13437: 13435: 13432: 13430: 13427: 13425: 13422: 13420: 13417: 13415: 13412: 13410: 13407: 13405: 13402: 13400: 13397: 13395: 13392: 13390: 13387: 13385: 13382: 13380: 13377: 13375: 13372: 13370: 13367: 13365: 13362: 13360: 13357: 13356: 13355: 13352: 13348: 13345: 13343: 13340: 13338: 13335: 13333: 13330: 13328: 13325: 13323: 13320: 13318: 13315: 13313: 13310: 13309: 13308: 13305: 13301: 13298: 13296: 13293: 13292: 13291: 13288: 13286: 13283: 13281: 13278: 13274: 13271: 13269: 13266: 13264: 13261: 13259: 13256: 13255: 13254: 13251: 13249: 13246: 13244: 13241: 13239: 13236: 13234: 13231: 13225: 13222: 13220: 13217: 13215: 13212: 13210: 13207: 13205: 13202: 13201: 13200: 13197: 13193: 13190: 13188: 13185: 13183: 13180: 13178: 13175: 13173: 13170: 13168: 13165: 13163: 13160: 13158: 13155: 13153: 13150: 13148: 13145: 13143: 13140: 13138: 13135: 13133: 13130: 13128: 13125: 13123: 13120: 13118: 13115: 13114: 13113: 13110: 13109: 13108: 13107:Sp/KLF family 13105: 13101: 13098: 13096: 13093: 13092: 13091: 13088: 13084: 13081: 13079: 13076: 13074: 13071: 13070: 13069: 13066: 13062: 13059: 13057: 13054: 13052: 13049: 13048: 13047: 13044: 13040: 13037: 13035: 13032: 13031: 13030: 13027: 13023: 13020: 13018: 13015: 13013: 13010: 13008: 13005: 13003: 13000: 12998: 12995: 12993: 12990: 12989: 12988: 12985: 12983: 12980: 12978: 12975: 12971: 12968: 12966: 12963: 12961: 12958: 12956: 12953: 12952: 12951: 12948: 12946: 12943: 12941: 12938: 12934: 12931: 12929: 12926: 12924: 12921: 12920: 12919: 12918: 12914: 12912: 12909: 12908: 12901: 12898: 12896: 12893: 12891: 12888: 12886: 12883: 12881: 12878: 12876: 12873: 12871: 12868: 12866: 12863: 12862: 12861: 12858: 12856: 12853: 12851: 12848: 12844: 12841: 12839: 12836: 12835: 12834: 12831: 12829: 12826: 12824: 12821: 12819: 12816: 12815: 12814: 12811: 12810: 12808: 12806: 12795: 12789: 12786: 12782: 12779: 12777: 12774: 12772: 12769: 12768: 12767: 12764: 12760: 12757: 12755: 12752: 12750: 12747: 12745: 12742: 12740: 12737: 12735: 12732: 12731: 12730: 12727: 12726: 12724: 12722: 12715: 12705: 12702: 12700: 12697: 12696: 12694: 12691: 12686: 12680: 12677: 12676: 12674: 12671: 12666: 12660: 12657: 12655: 12652: 12651: 12649: 12646: 12641: 12633: 12630: 12628: 12625: 12623: 12620: 12619: 12618: 12615: 12614: 12612: 12609: 12604: 12596: 12593: 12591: 12588: 12586: 12583: 12582: 12581: 12578: 12574: 12571: 12569: 12566: 12564: 12561: 12557: 12554: 12552: 12549: 12548: 12547: 12544: 12542: 12539: 12538: 12537: 12534: 12533: 12531: 12528: 12523: 12517: 12514: 12510: 12507: 12505: 12502: 12501: 12500: 12497: 12493: 12490: 12488: 12485: 12483: 12480: 12479: 12478: 12475: 12473: 12470: 12466: 12463: 12461: 12458: 12457: 12456: 12453: 12451: 12448: 12444: 12441: 12439: 12435: 12434: 12433: 12430: 12429: 12427: 12424: 12419: 12413: 12410: 12406: 12403: 12401: 12398: 12397: 12396: 12393: 12389: 12386: 12384: 12381: 12379: 12376: 12375: 12374: 12371: 12367: 12364: 12362: 12359: 12357: 12354: 12353: 12352: 12349: 12347: 12344: 12340: 12337: 12335: 12332: 12330: 12327: 12326: 12325: 12322: 12318: 12315: 12313: 12310: 12309: 12308: 12305: 12303: 12300: 12298: 12295: 12291: 12288: 12286: 12283: 12282: 12281: 12278: 12277: 12275: 12272: 12267: 12264: 12262: 12255: 12252: 12248: 12244: 12239: 12236: 12231: 12227: 12211: 12208: 12206: 12203: 12201: 12198: 12196: 12193: 12191: 12188: 12187: 12186: 12183: 12182: 12180: 12178: 12174: 12166: 12163: 12161: 12158: 12156: 12153: 12151: 12148: 12146: 12143: 12141: 12138: 12136: 12133: 12132: 12131: 12128: 12127: 12125: 12123: 12119: 12110: 12107: 12103: 12100: 12098: 12095: 12094: 12093: 12090: 12086: 12083: 12081: 12078: 12076: 12073: 12071: 12068: 12066: 12063: 12062: 12061: 12058: 12057: 12056: 12053: 12049: 12046: 12044: 12041: 12039: 12036: 12034: 12031: 12030: 12029: 12026: 12025: 12023: 12021: 12017: 12011: 12008: 12004: 12001: 11999: 11996: 11995: 11994: 11991: 11989: 11986: 11984: 11981: 11979: 11976: 11974: 11971: 11969: 11966: 11964: 11961: 11957: 11954: 11952: 11949: 11948: 11947: 11944: 11942: 11939: 11938: 11936: 11934: 11931: 11927: 11917: 11914: 11913: 11911: 11903: 11895: 11892: 11890: 11887: 11885: 11882: 11881: 11880: 11877: 11873: 11870: 11868: 11865: 11863: 11860: 11858: 11855: 11853: 11850: 11848: 11845: 11843: 11840: 11839: 11838: 11835: 11834: 11832: 11826: 11818: 11815: 11813: 11810: 11808: 11805: 11803: 11800: 11799: 11798: 11795: 11793: 11790: 11786: 11783: 11781: 11778: 11776: 11773: 11772: 11771: 11768: 11767: 11765: 11759: 11751: 11748: 11746: 11743: 11742: 11741: 11738: 11734: 11731: 11729: 11726: 11724: 11721: 11719: 11716: 11715: 11714: 11711: 11707: 11704: 11702: 11699: 11697: 11694: 11693: 11691: 11687: 11684: 11682: 11679: 11677: 11674: 11673: 11672: 11669: 11667: 11664: 11660: 11657: 11655: 11652: 11651: 11650: 11647: 11645: 11642: 11640: 11637: 11636: 11634: 11631: 11623: 11617: 11614: 11612: 11609: 11605: 11602: 11600: 11597: 11595: 11592: 11591: 11590: 11587: 11585: 11582: 11581: 11579: 11573: 11567: 11564: 11558: 11555: 11553: 11550: 11549: 11548: 11545: 11543: 11540: 11539: 11538: 11535: 11531: 11528: 11526: 11523: 11522: 11521: 11518: 11514: 11511: 11509: 11506: 11505: 11504: 11501: 11497: 11494: 11492: 11489: 11487: 11484: 11483: 11482: 11479: 11475: 11472: 11470: 11467: 11466: 11465: 11462: 11458: 11455: 11453: 11450: 11448: 11445: 11443: 11440: 11439: 11438: 11435: 11433: 11430: 11426: 11423: 11421: 11418: 11417: 11416: 11413: 11411: 11408: 11404: 11401: 11399: 11396: 11395: 11394: 11391: 11390: 11388: 11382: 11379: 11376: 11372: 11368: 11362: 11359: 11355: 11352: 11350: 11347: 11345: 11342: 11341: 11340: 11337: 11335: 11332: 11330: 11327: 11323: 11320: 11318: 11315: 11313: 11310: 11308: 11305: 11304: 11303: 11300: 11296: 11293: 11291: 11288: 11286: 11283: 11281: 11278: 11277: 11276: 11273: 11271: 11268: 11266: 11263: 11261: 11258: 11256: 11253: 11251: 11248: 11246: 11243: 11239: 11236: 11234: 11231: 11229: 11226: 11225: 11224: 11221: 11217: 11214: 11212: 11209: 11207: 11204: 11202: 11199: 11197: 11194: 11192: 11189: 11188: 11187: 11184: 11182: 11179: 11177: 11174: 11170: 11167: 11165: 11162: 11161: 11160: 11157: 11153: 11150: 11148: 11145: 11143: 11140: 11138: 11135: 11133: 11130: 11128: 11125: 11123: 11120: 11118: 11115: 11114: 11113: 11110: 11106: 11103: 11101: 11098: 11096: 11093: 11091: 11088: 11086: 11083: 11081: 11078: 11076: 11073: 11071: 11068: 11067: 11066: 11063: 11062: 11060: 11057: 11053: 11050: 11046: 11042: 11038: 11033: 11029: 11025: 11021: 11014: 11009: 11007: 11002: 11000: 10995: 10994: 10991: 10984: 10980: 10979: 10974: 10970: 10966: 10963: 10959: 10958: 10953: 10949: 10945: 10942: 10938: 10937: 10932: 10931: 10926: 10923: 10919: 10916: 10914: 10911: 10909: 10906: 10904: 10901: 10899: 10896: 10895: 10874: 10867: 10866: 10860: 10849: 10845: 10840: 10830:on 2012-02-22 10826: 10822: 10815: 10810: 10809: 10795: 10791: 10786: 10781: 10777: 10773: 10769: 10765: 10761: 10754: 10746: 10742: 10737: 10732: 10728: 10724: 10721:(2): 670–82. 10720: 10716: 10712: 10705: 10697: 10693: 10688: 10683: 10680:(8): 6511–9. 10679: 10675: 10671: 10664: 10656: 10652: 10647: 10642: 10638: 10634: 10630: 10623: 10615: 10611: 10606: 10601: 10597: 10593: 10590:(3): 359–69. 10589: 10585: 10581: 10574: 10566: 10562: 10557: 10552: 10548: 10544: 10540: 10533: 10525: 10521: 10516: 10511: 10507: 10503: 10499: 10492: 10484: 10480: 10475: 10470: 10466: 10462: 10458: 10451: 10443: 10439: 10434: 10429: 10425: 10421: 10417: 10410: 10402: 10398: 10393: 10388: 10383: 10378: 10374: 10370: 10366: 10362: 10358: 10351: 10343: 10339: 10335: 10331: 10327: 10323: 10320:(2): 129–33. 10319: 10315: 10308: 10300: 10296: 10291: 10286: 10281: 10276: 10272: 10268: 10264: 10260: 10256: 10249: 10241: 10237: 10232: 10227: 10223: 10219: 10215: 10208: 10200: 10196: 10192: 10188: 10185:(1): 179–87. 10184: 10180: 10172: 10164: 10160: 10155: 10150: 10146: 10142: 10138: 10131: 10123: 10119: 10114: 10109: 10106:(1): 117–30. 10105: 10101: 10097: 10090: 10082: 10078: 10073: 10068: 10064: 10060: 10056: 10049: 10041: 10037: 10033: 10029: 10025: 10021: 10014: 10006: 10002: 9997: 9992: 9988: 9984: 9980: 9973: 9965: 9961: 9958:(5): 2112–8. 9957: 9953: 9946: 9938: 9934: 9929: 9924: 9921:(2): 1240–8. 9920: 9916: 9912: 9905: 9897: 9893: 9888: 9883: 9879: 9875: 9871: 9864: 9856: 9852: 9847: 9842: 9838: 9834: 9830: 9823: 9815: 9811: 9806: 9801: 9797: 9793: 9789: 9785: 9781: 9774: 9766: 9762: 9757: 9752: 9748: 9744: 9740: 9733: 9725: 9721: 9716: 9711: 9707: 9703: 9699: 9692: 9684: 9680: 9675: 9670: 9666: 9662: 9658: 9651: 9643: 9639: 9634: 9629: 9625: 9621: 9617: 9610: 9602: 9598: 9593: 9588: 9584: 9580: 9576: 9569: 9561: 9557: 9552: 9547: 9543: 9539: 9535: 9528: 9520: 9516: 9511: 9506: 9502: 9498: 9494: 9490: 9486: 9479: 9471: 9467: 9462: 9457: 9453: 9449: 9445: 9438: 9436: 9427: 9423: 9418: 9413: 9409: 9405: 9401: 9394: 9386: 9382: 9377: 9372: 9369:(6): 3700–4. 9368: 9364: 9360: 9353: 9345: 9341: 9336: 9331: 9327: 9323: 9319: 9312: 9304: 9300: 9295: 9290: 9287:(5): 3280–5. 9286: 9282: 9278: 9271: 9269: 9260: 9256: 9251: 9246: 9242: 9238: 9234: 9227: 9219: 9215: 9210: 9205: 9201: 9197: 9193: 9186: 9178: 9174: 9169: 9164: 9160: 9156: 9152: 9145: 9137: 9133: 9128: 9123: 9119: 9115: 9111: 9104: 9096: 9092: 9087: 9082: 9079:(4): 661–73. 9078: 9074: 9070: 9063: 9055: 9051: 9046: 9041: 9037: 9033: 9029: 9022: 9014: 9010: 9005: 9000: 8997:(8): 7131–5. 8996: 8992: 8988: 8981: 8973: 8969: 8964: 8959: 8955: 8951: 8947: 8940: 8932: 8928: 8923: 8918: 8914: 8910: 8906: 8899: 8891: 8887: 8882: 8877: 8872: 8867: 8863: 8859: 8855: 8851: 8847: 8840: 8832: 8828: 8823: 8818: 8813: 8808: 8804: 8800: 8796: 8792: 8788: 8781: 8773: 8769: 8764: 8759: 8754: 8749: 8745: 8741: 8737: 8733: 8729: 8722: 8714: 8710: 8705: 8700: 8697:(1): 117–28. 8696: 8692: 8688: 8681: 8673: 8669: 8664: 8659: 8655: 8651: 8647: 8640: 8638: 8636: 8627: 8623: 8618: 8613: 8609: 8605: 8601: 8597: 8593: 8586: 8578: 8574: 8569: 8564: 8560: 8556: 8555:Endocrinology 8552: 8545: 8537: 8533: 8528: 8523: 8519: 8515: 8511: 8507: 8503: 8496: 8494: 8492: 8483: 8479: 8474: 8469: 8465: 8461: 8457: 8450: 8448: 8439: 8435: 8430: 8425: 8421: 8417: 8413: 8409: 8405: 8398: 8390: 8386: 8381: 8376: 8372: 8368: 8364: 8357: 8349: 8345: 8340: 8335: 8331: 8327: 8323: 8316: 8308: 8304: 8299: 8294: 8290: 8286: 8282: 8275: 8267: 8263: 8258: 8253: 8249: 8245: 8241: 8237: 8233: 8226: 8218: 8214: 8209: 8204: 8200: 8196: 8192: 8188: 8184: 8177: 8175: 8166: 8162: 8158: 8154: 8150: 8146: 8143:(8): 803–12. 8142: 8138: 8131: 8123: 8119: 8115: 8111: 8108:(8): 2393–9. 8107: 8103: 8095: 8087: 8083: 8078: 8073: 8069: 8065: 8061: 8054: 8052: 8043: 8039: 8034: 8029: 8025: 8021: 8017: 8010: 8002: 7998: 7993: 7988: 7984: 7980: 7976: 7969: 7961: 7957: 7953: 7949: 7941: 7933: 7929: 7924: 7919: 7916:(9): 1311–8. 7915: 7911: 7907: 7900: 7892: 7888: 7883: 7878: 7874: 7870: 7867:(1): 104–18. 7866: 7862: 7858: 7851: 7843: 7839: 7835: 7831: 7826: 7821: 7817: 7813: 7809: 7805: 7797: 7789: 7785: 7781: 7777: 7772: 7767: 7763: 7759: 7755: 7751: 7744: 7737: 7729: 7725: 7722:(4): 247–61. 7721: 7717: 7709: 7701: 7697: 7692: 7687: 7683: 7679: 7675: 7671: 7667: 7660: 7652: 7648: 7643: 7638: 7634: 7630: 7626: 7622: 7618: 7611: 7603: 7599: 7594: 7589: 7585: 7581: 7577: 7573: 7569: 7562: 7554: 7550: 7545: 7540: 7536: 7532: 7528: 7521: 7513: 7509: 7505: 7501: 7494: 7486: 7482: 7477: 7472: 7469:(3): 431–44. 7468: 7464: 7460: 7453: 7445: 7441: 7436: 7431: 7427: 7423: 7419: 7412: 7404: 7397: 7389: 7385: 7380: 7375: 7370: 7365: 7361: 7357: 7354:(5): 2122–7. 7353: 7349: 7345: 7338: 7330: 7326: 7322: 7318: 7314: 7310: 7303: 7301: 7299: 7290: 7286: 7281: 7276: 7272: 7268: 7264: 7257: 7249: 7245: 7240: 7235: 7232:(1): 107–18. 7231: 7227: 7223: 7216: 7208: 7204: 7200: 7196: 7192: 7188: 7184: 7180: 7172: 7164: 7160: 7155: 7150: 7146: 7142: 7138: 7131: 7123: 7119: 7114: 7109: 7105: 7101: 7097: 7090: 7082: 7078: 7073: 7068: 7063: 7058: 7054: 7050: 7046: 7042: 7038: 7031: 7023: 7019: 7014: 7009: 7005: 7001: 6997: 6990: 6982: 6978: 6973: 6968: 6963: 6958: 6954: 6950: 6946: 6942: 6938: 6931: 6923: 6919: 6915: 6911: 6904: 6896: 6892: 6887: 6882: 6878: 6874: 6870: 6863: 6855: 6851: 6846: 6841: 6837: 6833: 6829: 6822: 6814: 6810: 6805: 6800: 6796: 6792: 6788: 6781: 6773: 6769: 6764: 6759: 6755: 6751: 6747: 6740: 6732: 6728: 6723: 6718: 6714: 6710: 6706: 6699: 6697: 6695: 6686: 6682: 6677: 6672: 6668: 6664: 6660: 6653: 6651: 6649: 6647: 6638: 6634: 6629: 6624: 6620: 6616: 6612: 6605: 6597: 6593: 6588: 6583: 6579: 6575: 6571: 6564: 6556: 6552: 6547: 6542: 6538: 6534: 6530: 6526: 6522: 6515: 6507: 6503: 6498: 6493: 6488: 6483: 6479: 6475: 6471: 6467: 6463: 6456: 6454: 6445: 6441: 6436: 6431: 6427: 6423: 6419: 6415: 6411: 6404: 6396: 6392: 6387: 6382: 6378: 6374: 6370: 6363: 6355: 6351: 6346: 6341: 6337: 6333: 6329: 6325: 6321: 6314: 6312: 6303: 6299: 6295: 6291: 6287: 6283: 6275: 6267: 6263: 6258: 6253: 6249: 6245: 6241: 6234: 6226: 6222: 6217: 6212: 6208: 6204: 6201:(2): 131–40. 6200: 6196: 6192: 6185: 6171: 6167: 6161: 6153: 6149: 6144: 6139: 6135: 6131: 6127: 6123: 6119: 6112: 6104: 6100: 6095: 6090: 6086: 6082: 6078: 6074: 6070: 6063: 6055: 6051: 6046: 6041: 6037: 6033: 6029: 6022: 6014: 6010: 6005: 6000: 5996: 5992: 5989:(8): 3960–9. 5988: 5984: 5983:Endocrinology 5980: 5973: 5965: 5961: 5956: 5951: 5947: 5943: 5939: 5935: 5931: 5924: 5916: 5912: 5908: 5904: 5900: 5896: 5889: 5887: 5878: 5874: 5870: 5864: 5860: 5856: 5852: 5848: 5841: 5833: 5829: 5824: 5819: 5815: 5811: 5807: 5800: 5798: 5789: 5785: 5780: 5775: 5770: 5765: 5761: 5757: 5753: 5746: 5738: 5734: 5729: 5724: 5720: 5716: 5712: 5705: 5697: 5693: 5688: 5683: 5679: 5675: 5671: 5667: 5663: 5656: 5648: 5644: 5639: 5634: 5630: 5626: 5622: 5618: 5614: 5607: 5599: 5595: 5590: 5585: 5580: 5575: 5571: 5567: 5563: 5559: 5555: 5548: 5540: 5536: 5531: 5526: 5521: 5516: 5512: 5508: 5504: 5497: 5489: 5485: 5480: 5475: 5470: 5465: 5461: 5457: 5453: 5446: 5438: 5434: 5429: 5424: 5420: 5416: 5413:(1): 99–116. 5412: 5408: 5404: 5397: 5389: 5385: 5381: 5377: 5373: 5369: 5365: 5361: 5354: 5346: 5342: 5337: 5332: 5329:(3): 309–19. 5328: 5324: 5320: 5313: 5305: 5301: 5296: 5291: 5286: 5281: 5277: 5273: 5270:(4): 1234–8. 5269: 5265: 5261: 5254: 5246: 5242: 5238: 5234: 5230: 5226: 5222: 5218: 5214: 5210: 5203: 5201: 5199: 5190: 5186: 5181: 5176: 5171: 5166: 5162: 5158: 5154: 5150: 5146: 5139: 5131: 5127: 5123: 5119: 5116:(2): 378–80. 5115: 5111: 5104: 5102: 5093: 5089: 5084: 5079: 5076:(2): 147–79. 5075: 5071: 5067: 5060: 5052: 5048: 5043: 5038: 5034: 5030: 5026: 5022: 5018: 5011: 5003: 4999: 4995: 4991: 4987: 4983: 4980:(7): 671–80. 4979: 4975: 4968: 4960: 4956: 4952: 4948: 4943: 4938: 4934: 4930: 4926: 4919: 4911: 4907: 4902: 4897: 4893: 4889: 4885: 4881: 4877: 4873: 4869: 4862: 4854: 4850: 4846: 4842: 4838: 4834: 4827: 4819: 4815: 4811: 4807: 4803: 4799: 4795: 4791: 4784: 4776: 4772: 4767: 4762: 4757: 4752: 4748: 4744: 4740: 4736: 4732: 4725: 4717: 4713: 4708: 4703: 4699: 4695: 4691: 4687: 4683: 4679: 4675: 4668: 4660: 4656: 4651: 4646: 4642: 4638: 4634: 4630: 4626: 4619: 4617: 4608: 4604: 4599: 4594: 4590: 4586: 4582: 4575: 4567: 4563: 4558: 4553: 4549: 4545: 4541: 4534: 4526: 4522: 4517: 4512: 4508: 4504: 4500: 4496: 4492: 4485: 4477: 4473: 4468: 4463: 4459: 4455: 4451: 4447: 4443: 4436: 4428: 4424: 4419: 4414: 4410: 4406: 4402: 4395: 4387: 4383: 4378: 4373: 4369: 4365: 4361: 4354: 4346: 4342: 4337: 4332: 4328: 4324: 4320: 4313: 4305: 4301: 4296: 4291: 4287: 4283: 4279: 4272: 4264: 4260: 4255: 4250: 4246: 4242: 4238: 4234: 4230: 4223: 4215: 4211: 4207: 4203: 4198: 4193: 4189: 4185: 4181: 4174: 4166: 4162: 4157: 4152: 4148: 4144: 4140: 4133: 4125: 4121: 4117: 4113: 4109: 4105: 4098: 4090: 4086: 4082: 4078: 4074: 4070: 4063: 4055: 4051: 4046: 4041: 4037: 4033: 4029: 4022: 4014: 4010: 4005: 4000: 3997:(5): 543–58. 3996: 3992: 3988: 3981: 3973: 3969: 3965: 3961: 3958:(3): 217–21. 3957: 3953: 3946: 3938: 3934: 3930: 3926: 3925: 3917: 3909: 3905: 3901: 3897: 3893: 3889: 3885: 3881: 3874: 3866: 3862: 3857: 3852: 3848: 3844: 3840: 3833: 3831: 3822: 3818: 3814: 3810: 3806: 3802: 3795: 3787: 3783: 3779: 3775: 3771: 3767: 3764:(5): 463–92. 3763: 3759: 3752: 3744: 3740: 3736: 3732: 3729:(3): 443–59. 3728: 3724: 3717: 3709: 3705: 3701: 3695: 3691: 3687: 3683: 3676: 3668: 3664: 3660: 3656: 3652: 3648: 3645:(4): 782–97. 3644: 3640: 3632: 3624: 3620: 3615: 3610: 3606: 3602: 3598: 3591: 3583: 3579: 3574: 3569: 3566:(3): 235–57. 3565: 3561: 3557: 3550: 3542: 3538: 3534: 3530: 3526: 3522: 3515: 3507: 3503: 3499: 3495: 3491: 3487: 3480: 3472: 3468: 3462: 3454: 3450: 3444: 3437: 3433: 3428: 3426: 3424: 3416: 3412: 3407: 3405: 3403: 3398: 3388: 3385: 3383: 3380: 3379: 3369: 3366: 3363: 3360: 3357: 3354: 3351: 3348: 3345: 3342: 3339: 3336: 3333: 3330: 3327: 3324: 3321: 3318: 3315: 3312: 3309: 3306: 3303: 3300: 3297: 3294: 3291: 3288: 3285: 3282: 3279: 3276: 3273: 3270: 3267: 3264: 3261: 3258: 3255: 3252: 3249: 3246: 3243: 3240: 3237: 3234: 3231: 3228: 3225: 3222: 3219: 3216: 3213: 3210: 3207: 3204: 3201: 3198: 3195: 3192: 3189: 3186: 3183: 3180: 3177: 3174: 3171: 3168: 3165: 3162: 3159: 3156: 3153: 3150: 3147: 3144: 3141: 3138: 3135: 3132: 3129: 3126: 3123: 3120: 3117: 3114: 3111: 3108: 3105: 3102: 3099: 3096: 3093: 3090: 3087: 3084: 3081: 3078: 3075: 3072: 3069: 3066: 3063: 3060: 3057: 3054: 3051: 3048: 3045: 3042: 3039: 3036: 3033: 3030: 3027: 3024: 3021: 3018: 3015: 3012: 3009: 3006: 3003: 3000: 2997: 2994: 2991: 2988: 2987: 2985: 2983: 2973: 2971: 2967: 2957: 2955: 2951: 2947: 2943: 2939: 2935: 2931: 2927: 2923: 2922:antiandrogens 2919: 2906: 2902: 2898: 2894: 2891: 2888: 2884: 2880: 2876: 2872: 2868: 2864: 2861: 2858: 2854: 2850: 2846: 2842: 2839: 2838: 2829: 2825: 2821: 2818: 2817: 2808: 2804: 2800: 2796: 2792: 2788: 2784: 2781: 2778: 2775: 2771: 2767: 2763: 2759: 2755: 2752: 2749: 2748: 2731: 2725: 2716: 2712: 2707: 2703: 2699: 2697: 2693: 2689: 2687: 2683: 2679: 2677: 2673: 2669: 2667: 2663: 2659: 2657: 2653: 2649: 2647: 2643: 2639: 2637: 2633: 2627: 2618: 2611: 2606: 2604: 2599: 2597: 2592: 2591: 2582: 2580: 2576: 2571: 2563: 2561: 2557: 2553: 2549: 2537: 2533: 2530: 2526: 2522: 2519: 2515: 2511: 2508: 2507: 2505: 2502: 2500: 2496: 2493: 2488: 2487: 2485: 2481: 2478: 2473: 2469: 2465: 2462: 2458: 2455: 2450: 2446: 2445:phenylalanine 2442: 2441: 2439: 2435: 2434: 2432: 2429: 2428: 2427: 2425: 2421: 2417: 2404: 2401: 2398: 2395: 2391: 2387: 2383: 2379: 2376: 2375: 2374: 2372: 2368: 2364: 2351: 2347: 2342: 2333: 2331: 2326: 2316: 2313: 2303: 2301: 2300:polymorphisms 2298: 2294: 2290: 2286: 2282: 2272: 2270: 2266: 2263: 2248: 2246: 2245:ion transport 2242: 2238: 2234: 2224: 2222: 2218: 2214: 2210: 2206: 2202: 2198: 2194: 2190: 2186: 2181: 2179: 2175: 2170: 2168: 2164: 2160: 2159:messenger RNA 2156: 2152: 2148: 2144: 2140: 2136: 2132: 2127: 2123: 2121: 2117: 2102: 2100: 2096: 2092: 2087: 2085: 2081: 2071: 2069: 2065: 2055: 2053: 2049: 2045: 2041: 2040:Knockout-mice 2037: 2035: 2031: 2027: 2023: 2022:aromatization 2019: 2014: 2012: 2008: 2004: 2000: 1996: 1992: 1991:Wolffian duct 1988: 1984: 1969: 1967: 1963: 1959: 1956: 1951: 1949: 1945: 1941: 1937: 1933: 1929: 1925: 1922: 1918: 1914: 1910: 1906: 1896: 1884: 1881: 1879: 1875: 1872: 1868: 1864: 1861: 1859: 1855: 1851: 1847: 1844: 1841: 1837: 1832: 1828: 1825: 1822: 1820: 1816: 1813: 1810: 1808: 1804: 1800: 1796: 1791: 1784: 1779: 1774: 1763: 1758: 1754: 1750: 1747: 1743: 1736: 1734: 1731: 1727: 1723: 1719: 1716: 1712: 1708: 1701: 1699: 1693: 1689: 1686: 1680: 1678: 1674: 1668: 1664: 1660: 1656: 1652: 1648: 1644: 1641: 1637: 1630: 1628: 1622: 1618: 1615: 1609: 1607: 1603: 1599: 1595: 1591: 1585: 1581: 1578: 1576:RefSeq (mRNA) 1574: 1567: 1566: 1561: 1557: 1554: 1548: 1547: 1543: 1538: 1534: 1531: 1529: 1525: 1518: 1517: 1512: 1508: 1505: 1499: 1498: 1493: 1489: 1486: 1484: 1480: 1473: 1472: 1467: 1463: 1460: 1454: 1453: 1448: 1444: 1441: 1439: 1435: 1432: 1429: 1427: 1424: 1420: 1417: 1413: 1409: 1402: 1398: 1393: 1387: 1384: 1382: 1379: 1377: 1374: 1372: 1369: 1367: 1364: 1362: 1359: 1357: 1354: 1352: 1349: 1347: 1344: 1342: 1339: 1337: 1334: 1332: 1329: 1327: 1324: 1322: 1319: 1317: 1314: 1312: 1309: 1307: 1304: 1302: 1299: 1297: 1294: 1292: 1289: 1287: 1284: 1282: 1279: 1277: 1274: 1272: 1271:fertilization 1269: 1267: 1264: 1262: 1259: 1257: 1254: 1252: 1249: 1247: 1244: 1242: 1239: 1237: 1234: 1232: 1229: 1227: 1224: 1222: 1219: 1217: 1214: 1212: 1209: 1207: 1204: 1202: 1199: 1197: 1194: 1192: 1189: 1187: 1184: 1182: 1179: 1177: 1174: 1172: 1169: 1167: 1164: 1162: 1159: 1157: 1154: 1152: 1149: 1147: 1144: 1142: 1139: 1137: 1134: 1132: 1129: 1127: 1124: 1122: 1119: 1117: 1114: 1112: 1109: 1107: 1104: 1102: 1099: 1097: 1094: 1092: 1089: 1087: 1084: 1082: 1079: 1077: 1074: 1073: 1071: 1068: 1067: 1061: 1058: 1056: 1055:nuclear speck 1053: 1051: 1048: 1046: 1043: 1041: 1038: 1036: 1033: 1031: 1028: 1027: 1025: 1022: 1021: 1015: 1012: 1010: 1007: 1005: 1002: 1000: 997: 995: 992: 990: 987: 985: 982: 980: 977: 975: 972: 970: 967: 965: 962: 960: 957: 955: 952: 950: 947: 945: 942: 940: 937: 935: 932: 930: 927: 925: 922: 920: 917: 915: 912: 910: 909:lipid binding 907: 905: 902: 901: 899: 896: 895: 892: 891:Gene ontology 888: 884: 872: 867: 863: 856: 851: 848: 846: 842: 834: 829: 818: 814: 810: 806: 802: 798: 794: 790: 786: 782: 781: 778: 774: 769: 766: 756: 752: 748: 744: 740: 736: 732: 728: 724: 720: 719: 716: 712: 707: 704: 703: 700: 698: 694: 692: 691: 687: 686: 683: 681: 677: 673: 669: 665: 657: 652: 648: 644: 639: 629: 625: 618: 611: 605: 598: 590: 586: 582: 577: 573: 568: 564: 556: 551: 547: 543: 538: 528: 524: 517: 510: 504: 497: 493: 487: 483: 479: 474: 470: 465: 461: 457: 453: 449: 445: 441: 437: 433: 429: 425: 421: 413: 408: 401: 396: 391: 380: 378: 374: 370: 366: 362: 358: 354: 350: 346: 342: 338: 334: 330: 326: 322: 318: 314: 310: 306: 302: 298: 294: 290: 286: 282: 278: 274: 270: 266: 262: 258: 254: 250: 246: 242: 238: 234: 230: 226: 222: 218: 214: 210: 206: 202: 198: 194: 190: 186: 182: 178: 174: 170: 166: 162: 158: 154: 150: 146: 142: 138: 134: 130: 126: 122: 118: 114: 110: 106: 102: 98: 94: 90: 86: 82: 78: 72: 67: 64: 63: 59: 56: 49: 45: 40: 36: 32: 27: 22: 19: 18667:Testosterone 18453:Pyrilutamide 18405: 18397: 18389: 18354:Lavender oil 18344:Ketoconazole 18309:Enzalutamide 18279:Darolutamide 18213:Bicalutamide 18188:Atraric acid 18160: 18155: 18139:Trimegestone 18094:Promegestone 18059:Mifepristone 18034:Medrogestone 17979:Drospirenone 17934:Clascoterone 17865: 17831: 17775:JNJ-37654032 17770:JNJ-28330835 17765:JNJ-26146900 17661: 17605: 17585: 17570: 17552:Quingestanol 17469:Etonogestrel 17455: 17435: 17408: 17398: 17388: 17373: 17357:Propetandrol 17298: 17287:Oxymetholone 17262:Methasterone 17216: 17210:Tiomesterone 17200:Oxymesterone 17092: 17072: 16993:Norclostebol 16968: 16964: 16873: 16811:Mepitiostane 16806:Epitiostanol 16789:Drostanolone 16740:Androsterone 16696: 16677:+dutasteride 16673:Testosterone 16641:DHEA sulfate 16494: 16474: 16463: 16420: 16375: 16331: 16289: 16281: 16253: 16247: 16241: 16210: 16175: 16163: 16100: 16077: 16059: 16027: 15998: 15879: 15809: 15783: 15735: 15638: 15585: 15505: 15493: 15447: 15439: 15345: 15291: 15264: 15256: 15227: 15216: 14960:FOX proteins 14920:winged helix 14912: 14883: 14866: 14809: 14729: 14703: 14581: 14547: 14530: 14508: 14491: 14424: 14392: 14246: 14209: 14190: 14136: 14102: 14096: 13790: 13784: 13773: 13767:Antennapedia 13765: 13752: 13740: 13734: 13703: 13661: 13639: 13616: 13595: 13353: 13306: 13252: 13198: 13111: 13089: 13067: 13045: 13028: 12986: 12915: 12797: 12765: 12717: 12689: 12669: 12644: 12607: 12573:Progesterone 12540: 12526: 12422: 12270: 12256: 12250: 12234: 12176: 12129: 12121: 12019: 11929: 11878: 11836: 11796: 11769: 11739: 11712: 11546: 11536: 11519: 11502: 11414: 11370: 11338: 11301: 11158: 11048: 11036: 10976: 10955: 10935: 10929: 10880:. Retrieved 10873:the original 10864: 10852:. Retrieved 10832:. Retrieved 10825:the original 10820: 10767: 10763: 10753: 10718: 10714: 10704: 10677: 10673: 10663: 10636: 10632: 10622: 10587: 10583: 10573: 10546: 10542: 10532: 10505: 10501: 10491: 10464: 10460: 10450: 10423: 10419: 10409: 10364: 10360: 10350: 10317: 10314:The Prostate 10313: 10307: 10265:(2): 661–6. 10262: 10258: 10248: 10221: 10217: 10207: 10182: 10178: 10171: 10144: 10140: 10130: 10103: 10099: 10089: 10062: 10058: 10048: 10023: 10020:Biochemistry 10019: 10013: 9986: 9982: 9972: 9955: 9951: 9945: 9918: 9914: 9904: 9877: 9873: 9863: 9839:(1): 571–9. 9836: 9832: 9822: 9787: 9783: 9773: 9746: 9742: 9732: 9705: 9701: 9691: 9667:(2): 361–7. 9664: 9660: 9650: 9623: 9619: 9609: 9585:(1): 41–60. 9582: 9578: 9568: 9541: 9537: 9527: 9492: 9488: 9478: 9451: 9447: 9407: 9403: 9393: 9366: 9362: 9352: 9325: 9321: 9311: 9284: 9280: 9243:(1): 85–99. 9240: 9236: 9226: 9199: 9195: 9185: 9158: 9154: 9144: 9117: 9113: 9103: 9076: 9072: 9062: 9035: 9031: 9021: 8994: 8990: 8980: 8953: 8949: 8939: 8912: 8908: 8898: 8853: 8849: 8839: 8794: 8790: 8780: 8735: 8731: 8721: 8694: 8690: 8680: 8653: 8649: 8599: 8595: 8585: 8558: 8554: 8544: 8509: 8505: 8463: 8459: 8411: 8407: 8397: 8370: 8366: 8356: 8329: 8325: 8315: 8288: 8284: 8274: 8239: 8235: 8225: 8190: 8186: 8140: 8136: 8130: 8105: 8102:Biochemistry 8101: 8094: 8067: 8063: 8023: 8019: 8009: 7982: 7978: 7968: 7951: 7947: 7940: 7913: 7909: 7899: 7864: 7860: 7850: 7807: 7803: 7796: 7756:(1): 78–86. 7753: 7749: 7736: 7719: 7715: 7708: 7673: 7669: 7659: 7624: 7620: 7610: 7575: 7571: 7561: 7534: 7530: 7520: 7503: 7499: 7493: 7466: 7462: 7452: 7425: 7421: 7411: 7402: 7396: 7351: 7347: 7337: 7315:(3): 660–5. 7312: 7308: 7270: 7266: 7256: 7229: 7225: 7215: 7182: 7178: 7171: 7144: 7140: 7130: 7103: 7099: 7089: 7047:(2): 464–9. 7044: 7040: 7030: 7003: 6999: 6989: 6944: 6940: 6930: 6913: 6909: 6903: 6876: 6872: 6862: 6835: 6831: 6821: 6794: 6790: 6780: 6753: 6749: 6739: 6712: 6708: 6669:(1): 70–85. 6666: 6662: 6618: 6614: 6604: 6577: 6573: 6563: 6528: 6524: 6514: 6469: 6465: 6417: 6413: 6403: 6376: 6372: 6362: 6327: 6323: 6288:(2): 251–5. 6285: 6281: 6274: 6247: 6243: 6233: 6198: 6194: 6184: 6173:. Retrieved 6169: 6160: 6125: 6121: 6111: 6076: 6072: 6062: 6035: 6031: 6021: 5986: 5982: 5972: 5937: 5933: 5923: 5898: 5894: 5850: 5846: 5840: 5813: 5809: 5759: 5755: 5745: 5718: 5714: 5704: 5672:(1): 63–72. 5669: 5665: 5655: 5620: 5616: 5606: 5561: 5557: 5547: 5510: 5506: 5496: 5459: 5455: 5445: 5410: 5406: 5396: 5366:(2): 87–93. 5363: 5359: 5353: 5326: 5322: 5312: 5267: 5263: 5253: 5212: 5208: 5152: 5148: 5138: 5113: 5109: 5073: 5069: 5059: 5024: 5020: 5010: 4977: 4973: 4967: 4932: 4928: 4918: 4878:(1): 18577. 4875: 4871: 4861: 4839:(1): 241–8. 4836: 4832: 4826: 4793: 4789: 4783: 4738: 4734: 4724: 4681: 4677: 4667: 4632: 4628: 4588: 4584: 4574: 4547: 4543: 4533: 4498: 4494: 4484: 4449: 4445: 4435: 4408: 4404: 4394: 4367: 4363: 4353: 4326: 4322: 4312: 4285: 4281: 4271: 4236: 4232: 4222: 4187: 4183: 4173: 4146: 4142: 4132: 4107: 4103: 4097: 4072: 4068: 4062: 4035: 4031: 4021: 3994: 3990: 3980: 3955: 3951: 3945: 3928: 3922: 3916: 3883: 3879: 3873: 3846: 3842: 3804: 3800: 3794: 3761: 3757: 3751: 3726: 3722: 3716: 3681: 3675: 3642: 3638: 3631: 3614:10.2741/1063 3604: 3600: 3590: 3563: 3559: 3549: 3524: 3520: 3514: 3489: 3485: 3479: 3470: 3461: 3452: 3443: 3020:Calmodulin 1 3002:Beta-catenin 2979: 2976:Interactions 2963: 2938:nonsteroidal 2915: 2879:enzalutamide 2875:bicalutamide 2791:metandienone 2758:testosterone 2728:Relative to 2724: 2715: 2705: 2666:Bicalutamide 2572: 2569: 2547: 2546: 2531: 2503: 2494: 2479: 2437: 2430: 2423: 2419: 2413: 2402: 2393: 2377: 2370: 2366: 2360: 2349: 2345: 2330:enzalutamide 2322: 2309: 2285:X chromosome 2278: 2275:Deficiencies 2271:at Xq11–12. 2269:X chromosome 2261: 2259: 2230: 2182: 2171: 2147:dimerization 2143:cell nucleus 2128: 2124: 2113: 2088: 2077: 2061: 2054:mechanisms. 2038: 2020:produced by 2015: 1980: 1952: 1928:testosterone 1926:, including 1912: 1908: 1904: 1902: 1695: 1670: 1663:NP_001334993 1659:NP_001334992 1655:NP_001334990 1651:NP_001011645 1624: 1606:NM_001348064 1602:NM_001348063 1598:NM_001348061 1590:NM_001011645 1587: 1563: 1540: 1514: 1495: 1469: 1450: 1430: 1425: 819:vas deferens 799:cumulus cell 695: 688: 415:External IDs 74: 18: 18652:Osteocalcin 18533:Vinclozolin 18518:Thalidomide 18513:Seviteronel 18443:Procymidone 18379:Masofaniten 18334:Inocoterone 18238:bisphenol S 18234:bisphenol F 18230:bisphenol A 18208:BAY-1024767 18183:Apalutamide 18129:Spiroxasone 18124:Spirorenone 18104:Rosterolone 18044:Mespirenone 17989:Edogestrone 17959:Delanterone 17949:Cyproterone 17939:Clometerone 17909:Benorterone 17894:Abiraterone 17859:Antagonists 17790:PF-06260414 17695:BMS-564,929 17619:Alternariol 17511:Lynestrenol 17464:Desogestrel 17347:Norboletone 17337:Metribolone 17282:Oxandrolone 17240:Mestanolone 17205:Penmesterol 17136:Formebolone 17101:Calusterone 17096:Bolasterone 16850:Prostanozol 16821:Mesterolone 16101:(4.11) Runt 13756:Homeodomain 13354:zinc finger 12690:subfamily 0 12670:subfamily 6 12645:subfamily 5 12608:subfamily 4 12527:subfamily 3 12423:subfamily 2 12271:subfamily 1 12238:Zinc finger 11481:Neurogenins 11049:(1.1) Basic 7825:2158/395763 7771:2158/395766 5940:(1): 3–23. 3886:(2): 71–7. 3807:(1): 1–28. 3527:(1): 42–8. 2946:antagonists 2897:bisphenol A 2883:apalutamide 2835:Antagonists 2803:oxandrolone 2730:Metribolone 2700:<0.0057 2636:Metribolone 2615:Affinities 2575:coregulator 2518:coactivator 2397:proteolysis 2390:amino acids 2312:CAG repeats 2306:CAG repeats 2227:Non-genomic 2215:-dependent 2189:acetylation 2093:(CAIS) and 2064:osteoblasts 1955:DNA-binding 1793:Identifiers 1673:NP_000035.2 1171:cell growth 1030:nucleoplasm 979:DNA binding 741:human penis 654:97,366,821 641:97,192,375 553:67,730,619 540:67,544,021 393:Identifiers 18722:Categories 18646:-ornithine 18589:gadolinium 18438:Prochloraz 18433:Phenothrin 18413:Nilutamide 18384:Methiocarb 18304:Endosulfan 18269:Cioteronel 18264:Cimetidine 18254:BMS-641988 18249:BMS-570511 18244:BMS-501949 18218:Bisphenols 18173:Antarlides 18149:Zanoterone 18084:Oxendolone 18029:Ludaterone 18019:Galeterone 17969:Dicirenone 17866:Steroidal: 17832:Steroidal: 17825:Vosilasarm 17720:GSK2881078 17675:AC-262,536 17634:Trilostane 17542:Norgestrel 17491:Gestrinone 17459:Δ-Tibolone 17342:Mibolerone 17292:Stanozolol 17245:Metenolone 17022:Trenbolone 16981:Nandrolone 16931:Dienedione 16855:Stenbolone 16816:Mesabolone 16668:Silandrone 16663:Quinbolone 16658:Plomestane 16653:Formestane 16648:Exemestane 16570:Atamestane 16467:modulators 14634:POU domain 13774:ANTP class 13704:(2.6) WRKY 12987:GLI family 12122:(1.5) RF-X 12020:(1.4) NF-1 10882:2008-04-29 10854:2008-04-29 10834:2008-04-29 6175:2016-02-27 5513:: 100240. 3438:, May 2017 3417:, May 2017 3393:References 3026:Caveolin 1 2871:nilutamide 2857:oxendolone 2807:stanozolol 2799:trenbolone 2795:nandrolone 2751:Endogenous 2676:Nilutamide 2536:C-terminal 2468:activation 2386:N-terminus 2084:trabecular 2068:osteocytes 1948:progestins 1921:androgenic 1846:structures 699:(ortholog) 436:HomoloGene 18632:-arginine 18617:Estradiol 18597:strontium 18593:magnesium 18581:aluminium 18548:YM-175735 18483:Ro 5-2537 18478:Ro 2-7239 18428:PF-998425 18423:Pentomone 18364:LG-120907 18324:Flutamide 18319:Fenarimol 18259:CH5137291 18198:Bakuchiol 18134:Topterone 18099:Prorenone 18074:Osaterone 18069:Nordinone 18054:Mexrenone 17974:Dienogest 17924:Canrenone 17845:TFM-4AS-1 17785:ORM-11984 17725:GSK-4336A 17715:GLPG-0492 17639:ZM-182345 17486:Gestodene 17474:Etynodiol 17230:Furazabol 17121:Enestebol 17049:Trendione 17010:Oxabolone 16936:Dienolone 16909:Bolandiol 16838:Nisterime 16592:Clostebol 16575:Boldenone 16421:see also 16262:Apetala 2 14916:Fork head 13596:(2.4) Cys 12798:(2.3) Cys 11530:Scleraxis 6079:(4): 29. 5779:1765/8892 5479:1765/8551 5245:250730778 4974:Neurology 4165:257943362 4104:Maturitas 3908:260321076 3050:Cyclin D1 2934:steroidal 2905:ralaniten 2867:flutamide 2828:enobosarm 2783:androgens 2780:Synthetic 2754:androgens 2696:Flutamide 2620:Compound 2336:Structure 2319:Mutations 2205:chromatin 2197:apoptosis 2163:ribosomes 2141:into the 2099:mutations 2048:ovulation 1966:phenotype 1936:cytoplasm 1934:, in the 1824:IPR001103 1698:NP_038504 1647:NP_000035 1627:NM_013476 1594:NM_000044 1416:Orthologs 1035:cytoplasm 444:GeneCards 18683:See also 18570:Agonists 18543:YM-92088 18508:RU-58841 18503:RU-58642 18498:RU-57073 18493:RU-56187 18488:RU-22930 18418:ONC1-13B 18369:LGD-1331 18294:Dieldrin 18288:p,p’-DDE 18193:AZD-3514 18178:Arabilin 18109:RU-15328 18049:Metogest 17984:DU-41165 17820:S-101479 17800:RU-59063 17755:LGD-4033 17750:LGD-3303 17740:LGD-2226 17730:GSK-8698 17629:Drupanol 17624:Cl-4AS-1 17564:Tibolone 16745:Bolazine 16488:Agonists 15739:MADS box 13879:Homeobox 13791:Hox-like 13785:protoHOX 12546:Estrogen 12541:Androgen 12395:Rev-ErbA 11933:bHLH-ZIP 11908:bHLH-COE 11447:Myogenin 10848:Archived 10794:14609956 10745:11854421 10696:15598662 10655:12089345 10614:10654935 10565:10383460 10524:18451177 10483:10428808 10442:11856738 10401:10611280 10342:24134119 10334:12949936 10299:11792840 10240:11751884 10199:11322786 10163:11585838 10122:15027889 10081:15466214 10040:11735420 10005:12226080 9964:11280774 9937:11707452 9896:15031286 9855:10617653 9765:10085091 9724:11673464 9601:12200228 9560:12361945 9519:14966297 9470:15205473 9426:12039962 9344:11117529 9303:11719514 9259:11773441 9218:11278661 9177:12165860 9155:Oncogene 9136:10779504 9095:11923464 9054:12441355 9013:14645241 8972:10517667 8931:11818501 8890:10318905 8672:11779876 8626:11747336 8577:10965917 8536:12612084 8482:14966121 8438:10567563 8389:12163482 8348:10930412 8307:12218053 8266:18212060 8217:15684378 8165:24978960 8086:11994312 8042:15178691 8001:12958311 7960:12941811 7891:12482965 7842:23831527 7834:15288768 7804:Steroids 7788:46121331 7780:15305378 7728:12612053 7700:12864730 7651:15572661 7602:19351840 7553:10734072 7512:10344732 7485:15558026 7463:Oncogene 7444:11328859 7405:(1–528). 7329:12810069 7248:15691881 7207:24740136 7199:11719263 7163:11266437 7122:11278309 7081:14695896 6981:11016951 6922:11085509 6895:11916967 6854:12944908 6832:Oncogene 6813:12799378 6772:11792709 6731:15256534 6685:14593076 6596:11278763 6555:14517289 6506:11404460 6444:16159155 6395:24639562 6354:30565725 6266:11943742 6225:22414851 6152:25184630 6103:26902623 6054:12923188 6013:18420738 5964:24909511 5915:16397271 5877:37717994 5832:15178743 5696:17420290 5647:17189428 5598:15994236 5539:33384381 5437:36535377 5388:19706366 5345:11719283 5237:35859180 5189:29584789 5149:PLOS ONE 5092:17334586 5051:16981011 5002:45735233 4959:25940392 4910:31819097 4775:15263086 4716:23945587 4659:16923962 4607:15123687 4566:16434977 4544:Oncogene 4525:14612401 4476:11971970 4427:10779504 4386:15623502 4345:15753383 4304:17940184 4263:37791849 4254:10639085 4214:20933176 4206:22872761 4124:19372015 4089:12089231 4054:22836391 4013:20231167 3972:12868122 3937:12834017 3900:16633980 3865:12351684 3786:28436828 3778:12600226 3667:28626145 3659:17132855 3623:12700055 3541:15705293 3434:– 3413:– 3376:See also 3128:HSP90AA1 3104:Gelsolin 2982:interact 2942:agonists 2887:RU-58841 2824:andarine 2745:Agonists 2422:through 2418:labeled 2394:in vitro 2363:isoforms 2357:Isoforms 2325:enhancer 2251:Genetics 2235:such as 2187:through 2091:Complete 2080:knockout 2018:estrogen 1972:Function 1924:hormones 1863:RCSB PDB 1819:InterPro 1746:Wikidata 1395:Sources: 18639:-lysine 18627:(incl. 18585:calcium 18579:(incl. 18577:Cations 18374:Linuron 18314:EPI-001 18220:(e.g., 18009:EM-6537 18004:EM-5855 17999:EM-5854 17994:EM-4350 17840:MK-0773 17835:EM-9017 17815:S-40503 17670:ACP-105 17665:198RL26 17530:(e.g., 17503:(e.g., 17412:Danazol 17362:RU-2309 17302:Bolenol 16139:RUNX1T1 16119:CBFA2T3 16114:CBFA2T2 15994:TCF/LEF 14103:NK-like 14097:metaHOX 13800:ParaHox 13741:domains 12432:COUP-TF 11906:Group F 11829:Group E 11762:Group D 11626:Group C 11576:Group B 11520:Paraxis 11385:Group A 10983:PDBe-KB 10973:UniProt 10962:PDBe-KB 10952:UniProt 10369:Bibcode 10267:Bibcode 9814:9710597 9683:9675141 9642:9813067 9385:9920921 8858:Bibcode 8831:9636157 8799:Bibcode 8772:8643607 8740:Bibcode 8713:9892017 8617:2364015 8257:2268407 8157:1525041 8122:1540595 7932:8872471 7691:1223690 7593:2669850 7388:9482849 7356:Bibcode 7289:9822653 7049:Bibcode 7022:9211894 6949:Bibcode 6637:9565586 6474:Bibcode 6435:2096617 6345:6608750 6302:2788775 6216:3474193 6143:4201502 6094:4888068 6004:2488236 5955:4571323 5788:9717843 5737:8530400 5687:2064112 5638:1820481 5589:1168953 5566:Bibcode 5530:7949100 5488:7706276 5428:9841400 5380:2734982 5304:8108393 5272:Bibcode 5217:Bibcode 5180:5871002 5157:Bibcode 5130:9933058 5110:Urology 5042:1564432 4994:4233749 4951:8537246 4901:6901466 4880:Bibcode 4853:3377788 4818:3353726 4798:Bibcode 4790:Science 4743:Bibcode 4707:4034386 4686:Bibcode 4650:1636736 3821:3549275 3743:6371845 3708:9949684 3582:9845666 3506:7671849 3436:Ensembl 3415:Ensembl 3338:TGFB1I1 3140:MAGEA11 2968:of the 2930:ligands 2901:EPI-001 2895:(e.g., 2865:(e.g., 2843:(e.g., 2822:(e.g., 2785:(e.g., 2756:(e.g., 2585:Ligands 2449:leucine 2416:domains 2410:Domains 2139:cytosol 2110:Genomic 2095:partial 2026:Steroid 1987:agonist 1940:nucleus 1812:PF02166 1528:UniProt 1483:Ensembl 1422:Species 1401:QuickGO 1045:nucleus 1040:cytosol 725:urethra 674:pattern 400:Aliases 18562:GPRC6A 18538:YM-580 18468:RD-162 18359:LG-105 17710:FTBU-1 14852:Bicoid 14117:BARHL2 14112:BARHL1 13694:JMJD1B 13607:HIVEP1 12092:I-SMAD 12060:R-SMAD 11978:MLXIPL 11733:Period 11659:ARNTL2 11464:NeuroD 10978:P19091 10957:P10275 10927:Human 10924:(MeSH) 10792:  10785:275443 10782:  10743:  10733:  10694:  10653:  10612:  10605:305573 10602:  10563:  10522:  10481:  10440:  10399:  10389:  10340:  10332:  10297:  10290:117362 10287:  10238:  10197:  10161:  10120:  10079:  10038:  10003:  9962:  9935:  9894:  9853:  9812:  9805:109098 9802:  9763:  9722:  9681:  9640:  9599:  9558:  9517:  9510:350564 9507:  9468:  9424:  9383:  9342:  9301:  9257:  9216:  9175:  9134:  9093:  9052:  9011:  8970:  8929:  8888:  8878:  8829:  8819:  8770:  8760:  8711:  8670:  8624:  8614:  8575:  8534:  8527:149467 8524:  8480:  8436:  8426:  8387:  8346:  8305:  8264:  8254:  8215:  8208:548016 8205:  8163:  8155:  8120:  8084:  8040:  7999:  7958:  7930:  7889:  7882:140652 7879:  7840:  7832:  7786:  7778:  7726:  7698:  7688:  7649:  7642:533990 7639:  7600:  7590:  7551:  7510:  7483:  7442:  7386:  7376:  7327:  7287:  7246:  7205:  7197:  7161:  7120:  7079:  7072:327170 7069:  7020:  6979:  6969:  6920:  6893:  6852:  6811:  6770:  6729:  6683:  6635:  6594:  6553:  6546:230325 6543:  6504:  6494:  6442:  6432:  6393:  6352:  6342:  6300:  6264:  6223:  6213:  6150:  6140:  6101:  6091:  6052:  6011:  6001:  5962:  5952:  5913:  5875:  5865:  5830:  5786:  5735:  5694:  5684:  5645:  5635:  5596:  5586:  5537:  5527:  5486:  5435:  5425:  5386:  5378:  5343:  5302:  5292:  5243:  5235:  5209:Nature 5187:  5177:  5128:  5090:  5049:  5039:  5000:  4992:  4957:  4949:  4908:  4898:  4851:  4816:  4773:  4766:503720 4763:  4714:  4704:  4678:Nature 4657:  4647:  4605:  4564:  4523:  4516:262657 4513:  4474:  4467:133781 4464:  4425:  4384:  4343:  4302:  4261:  4251:  4212:  4204:  4163:  4122:  4087:  4052:  4011:  3970:  3935:  3906:  3898:  3863:  3819:  3784:  3776:  3741:  3706:  3696:  3665:  3657:  3621:  3580:  3539:  3504:  3350:TRIM68 3248:RANBP9 3134:HTATIP 3110:GNB2L1 3080:EFCAB6 3074:L-DOPA 2984:with: 2706:Notes: 2538:domain 2486:(DBD) 2461:ligand 2447:, L = 2438:B only 2145:, and 2001:, and 1946:, and 1878:PDBsum 1852:  1842:  1798:Symbol 1732:search 1730:PubMed 1565:P19091 1546:Q9NUA2 1542:P10275 1438:Entrez 845:BioGPS 729:nipple 424:313700 18226:BFDGE 18222:BADGE 18168:AA560 17850:YK-11 17760:LY305 17650:SARMs 16402:Sigma 16267:EREBP 16251:EREBP 16242:(0.5) 16211:(0.3) 16134:RUNX3 16129:RUNX2 16124:RUNX1 16068:TFCP2 15989:SSRP1 15810:(4.7) 15800:TBPL1 15784:(4.6) 15736:(4.4) 15586:(4.2) 15527:NFKB2 15522:NFKB1 15517:NF-κB 15506:(4.1) 15430:MYBL2 15217:(3.4) 14913:(3.3) 14862:BICD2 14837:SHOX2 14805:PROP1 14789:PRRX 14699:SATB2 14644:BRN-3 14639:PIT-1 14531:PKNOX 14446:TALE 14442:NOBOX 14415:HESX1 14388:CUTL1 14370:other 14264:NANOG 14127:BARX2 14122:BARX1 13874:MEOX2 13869:MEOX1 13753:(3.1) 13662:JARID 13635:GRLF1 13630:DIDO1 13290:Zbtb7 13280:TSHZ3 13248:PRDM9 13046:HIVEP 12911:ATBF1 12865:TFIIH 12850:TFIIF 12833:TFIIE 12828:TFIID 12823:TFIIB 12818:TFIIA 12788:TRPS1 12654:LRH-1 12632:NURR1 12622:NGFIB 12450:Ear-2 12251:(2.1) 11993:SREBP 11930:(1.3) 11692:NPAS 11681:EPAS1 11666:CLOCK 11654:ARNTL 11628:bHLH- 11604:n-Myc 11599:l-Myc 11594:c-Myc 11584:FIGLA 11566:Twist 11525:TCF15 11432:MESP2 11410:ATOH1 11403:ASCL2 11398:ASCL1 11329:NFIL3 11260:GABPA 11255:DDIT3 11186:C/EBP 11181:BLZF1 11142:c-Jun 11132:FOSL2 11127:FOSL1 11117:c-Fos 10876:(PDF) 10869:(PDF) 10828:(PDF) 10817:(PDF) 10736:65658 10392:24715 10338:S2CID 8881:21881 8822:22623 8763:39278 8429:84931 8161:S2CID 7838:S2CID 7784:S2CID 7746:(PDF) 7379:19270 7203:S2CID 6972:17187 6497:34646 5384:S2CID 5295:43131 5241:S2CID 4998:S2CID 4955:S2CID 4210:S2CID 4161:S2CID 4149:: X. 3904:S2CID 3782:S2CID 3758:Drugs 3663:S2CID 3368:ZMIZ1 3364:, and 3356:UBE2I 3314:STAT3 3290:SMAD3 3284:SIRT1 3278:SART3 3266:RNF14 3254:RCHY1 3242:RAD9A 3230:PRPF6 3224:PIAS2 3218:PATZ1 3206:PA2G4 3188:NCOR2 3182:NCOA6 3176:NCOA4 3170:NCOA3 3164:NCOA2 3158:NCOA1 3152:MYST2 3122:HDAC1 3116:GSK3B 3098:GAPDH 3092:FOXO1 3062:DACH1 3038:COX5B 3014:C-jun 3008:BRCA1 2814:Mixed 2690:0.57 2548:AR-V7 2466:Trans 2380:– 87 1960:that 1913:NR3C4 1471:11835 1431:Mouse 1426:Human 1397:Amigo 757:liver 733:vulva 697:Mouse 690:Human 637:Start 572:Mouse 536:Start 469:Human 432:88064 18658:SHBG 18601:zinc 18299:DIMP 17914:BOMT 17810:S-23 17700:DTIB 16371:MNDA 16290:ARID 16245:AP-2 16232:RBL2 16227:RBL1 16201:HBP1 16184:HMGA 16091:YBX1 16086:CSDA 16021:LEF1 15853:HMGN 15826:HMGB 15747:Mef2 15726:MYRF 15714:TBR2 15709:TBR1 15657:TP63 15597:STAT 15589:STAT 15549:NFAT 15542:RELB 15537:RELA 15492:(4) 15373:FLI1 15339:SPIB 15040:D4L6 15035:D4L5 15030:D4L4 15025:D4L3 15020:D4L1 14884:PITX 14847:VSX2 14842:VSX1 14832:SHOX 14810:PHOX 14492:MEIS 14420:HOPX 14356:VAX2 14351:VAX1 14346:TLX3 14341:TLX2 14336:TLX1 14331:NATO 14314:HMX3 14309:HMX2 14304:HMX1 14242:LBX2 14237:LBX1 14227:HHEX 14086:MNX1 14081:GBX2 14076:GBX1 13864:Evx2 13859:Evx1 13827:PDX1 13822:Xlox 13712:WRKY 13625:AIRE 13584:804A 13307:ZBTB 13253:SALL 13243:OSR1 13238:MYT1 13233:MTF1 13068:IKZF 13007:REST 12982:GFI1 12977:ERV3 12945:E4F1 12940:CTCF 12729:GATA 12699:DAX1 12679:GCNF 12627:NOR1 12455:HNF4 12324:PPAR 12257:(Cys 12185:AP-2 12055:SMAD 12010:USF1 11983:MXI1 11963:MITF 11956:MXD3 11951:MXD1 11941:AP-4 11916:EBF1 11792:Pho4 11770:BHLH 11649:ARNT 11644:AHRR 11616:TCF4 11611:MXD4 11542:LYL1 11503:OLIG 11457:MYF6 11452:MYF5 11442:MyoD 11415:HAND 11393:AS-C 11375:bHLH 11361:XBP1 11265:GCN4 11245:CREM 11223:CREB 11176:BATF 11159:BACH 11152:JunD 11147:JUNB 11137:JDP2 11122:FOSB 11112:AP-1 11070:AATF 11056:bZIP 11022:and 10971:for 10950:for 10790:PMID 10741:PMID 10692:PMID 10651:PMID 10610:PMID 10561:PMID 10520:PMID 10479:PMID 10438:PMID 10397:PMID 10330:PMID 10295:PMID 10236:PMID 10195:PMID 10159:PMID 10118:PMID 10077:PMID 10036:PMID 10001:PMID 9960:PMID 9933:PMID 9892:PMID 9851:PMID 9810:PMID 9761:PMID 9720:PMID 9679:PMID 9638:PMID 9597:PMID 9556:PMID 9515:PMID 9466:PMID 9422:PMID 9381:PMID 9340:PMID 9299:PMID 9255:PMID 9214:PMID 9173:PMID 9132:PMID 9091:PMID 9050:PMID 9009:PMID 8968:PMID 8927:PMID 8886:PMID 8827:PMID 8768:PMID 8709:PMID 8668:PMID 8622:PMID 8573:PMID 8532:PMID 8478:PMID 8434:PMID 8385:PMID 8344:PMID 8303:PMID 8262:PMID 8213:PMID 8153:PMID 8118:PMID 8082:PMID 8038:PMID 7997:PMID 7956:PMID 7928:PMID 7887:PMID 7830:PMID 7776:PMID 7724:PMID 7696:PMID 7647:PMID 7598:PMID 7549:PMID 7508:PMID 7481:PMID 7440:PMID 7384:PMID 7325:PMID 7285:PMID 7244:PMID 7195:PMID 7159:PMID 7118:PMID 7077:PMID 7018:PMID 6977:PMID 6918:PMID 6891:PMID 6850:PMID 6809:PMID 6768:PMID 6727:PMID 6681:PMID 6633:PMID 6592:PMID 6551:PMID 6502:PMID 6440:PMID 6391:PMID 6350:PMID 6298:PMID 6262:PMID 6221:PMID 6148:PMID 6099:PMID 6050:PMID 6009:PMID 5960:PMID 5911:PMID 5873:PMID 5863:ISBN 5828:PMID 5784:PMID 5733:PMID 5692:PMID 5643:PMID 5594:PMID 5535:PMID 5484:PMID 5433:PMID 5376:PMID 5341:PMID 5300:PMID 5233:PMID 5185:PMID 5126:PMID 5088:PMID 5047:PMID 4990:PMID 4947:PMID 4906:PMID 4849:PMID 4814:PMID 4771:PMID 4712:PMID 4655:PMID 4603:PMID 4562:PMID 4521:PMID 4472:PMID 4423:PMID 4382:PMID 4341:PMID 4300:PMID 4259:PMID 4202:PMID 4120:PMID 4085:PMID 4050:PMID 4009:PMID 3968:PMID 3933:PMID 3896:PMID 3861:PMID 3817:PMID 3774:PMID 3739:PMID 3704:PMID 3694:ISBN 3655:PMID 3619:PMID 3578:PMID 3537:PMID 3502:PMID 3344:TMF1 3320:SVIL 3272:RNF4 3236:PTEN 3212:PAK6 3200:p300 3194:NONO 3146:MED1 3032:CDK9 2996:BAG1 2990:AKT1 2680:0.9 2670:1.4 2660:7.8 2640:100 2534:) – 2482:) – 2403:AR-B 2378:AR-A 2369:and 2361:Two 2350:AR-B 2348:and 2346:AR-A 2323:The 2295:and 2265:gene 2256:Gene 2219:and 2155:gene 2066:and 2046:and 1930:and 1903:The 1871:PDBj 1867:PDBe 1850:ECOD 1840:Pfam 1807:Pfam 680:Bgee 628:Band 589:Chr. 532:Xq12 527:Band 486:Chr. 420:OMIM 377:5CJ6 373:4QL8 369:4OLM 365:4OKX 361:4OKW 357:4OKT 353:4OKB 349:4OK1 345:4OJB 341:4OJ9 337:4OIU 333:4OIL 329:4OHA 325:4OH6 321:4OH5 317:4OGH 313:4OFU 309:4OFR 305:4OEZ 301:4OEY 297:4OED 293:4OEA 289:4K7A 285:3RLL 281:3RLJ 277:3L3Z 273:3L3X 269:4HLW 265:3ZQT 261:3V4A 257:3V49 253:3BTR 249:3B68 245:3B67 241:3B66 237:3B65 233:3B5R 229:2Z4J 225:2YLQ 221:2YLP 217:2YLO 213:2YHD 209:2Q7K 205:2Q7J 201:2Q7I 197:2PNU 193:2PKL 189:2PIX 185:2PIW 181:2PIV 177:2PIU 173:2PIT 169:2PIR 165:2PIQ 161:2PIP 157:2PIO 153:2OZ7 149:2HVC 145:2AXA 141:2AX9 137:2AX8 133:2AX7 129:2AX6 125:2AO6 121:2AMB 117:2AMA 113:2AM9 109:1Z95 105:1XQ3 101:1XOW 97:1XJ7 93:1T65 89:1T63 85:1T5Z 81:1GS4 77:1E3G 58:RCSB 55:PDBe 18284:DDT 17805:S-1 17795:R-1 16398:Rho 16376:NFY 16349:MLL 16332:IFI 16327:CAP 16109:CBF 16028:TOX 15999:TCF 15984:SRY 15897:SOX 15880:HNF 15821:BBX 15795:TBP 15774:SRF 15719:TFT 15669:TBX 15662:p73 15652:p53 15532:REL 15425:MYB 15346:ETV 15334:ERG 15319:ETS 15314:ERF 15292:ELK 15287:EGF 15265:ELF 15229:HSF 14928:E2F 14867:OTX 14857:GSC 14827:RAX 14738:PAX 14704:ZEB 14677:3/4 14627:21A 14582:PHF 14548:SIX 14509:PBX 14485:MKX 14450:IRX 14425:LMX 14393:FHL 14383:CRX 14378:ARX 14324:6-2 14319:6-1 14299:3-2 14294:3-1 14289:2-5 14284:2-3 14279:2-2 14274:2-1 14269:NKX 14247:MSX 14232:HLX 14192:EMX 14154:DLX 14137:DBX 14132:BSX 14069:D13 14064:D12 14059:D11 14054:D10 14024:C13 14019:C12 14014:C11 14009:C10 13979:B13 13929:A13 13924:A11 13919:A10 13834:Cdx 13805:Gsx 13735:(3) 13640:ING 13579:655 13574:649 13569:644 13564:638 13559:593 13554:471 13549:452 13544:451 13539:423 13534:384 13529:366 13524:365 13519:350 13514:346 13509:330 13504:318 13499:300 13494:281 13489:268 13484:267 13479:259 13474:239 13469:238 13464:219 13459:217 13454:202 13449:165 13444:148 13439:146 13434:143 13394:33B 13285:WT1 13112:KLF 13090:ILF 13029:HIC 13022:YY1 12950:EGR 12933:11B 12928:11A 12917:BCL 12900:3C2 12895:3C1 12802:His 12766:MTA 12704:SHP 12659:SF1 12617:NUR 12516:TLX 12477:RXR 12472:PNR 12412:VDR 12373:ROR 12351:RAR 12346:PXR 12334:β/δ 12307:LXR 12302:FXR 12297:CAR 12235:(2) 12165:ANK 12130:RFX 12028:NFI 11988:Myc 11973:MLX 11968:MNT 11946:MAX 11879:HEY 11837:HES 11740:SIM 11713:PER 11671:HIF 11639:AhR 11630:PAS 11589:Myc 11547:TAL 11537:SLC 11339:NRF 11334:NRL 11302:NFE 11275:MAF 11270:HLF 11250:DBP 10969:PDB 10948:PDB 10780:PMC 10772:doi 10731:PMC 10723:doi 10682:doi 10678:280 10641:doi 10600:PMC 10592:doi 10551:doi 10547:274 10510:doi 10469:doi 10465:274 10428:doi 10424:277 10387:PMC 10377:doi 10322:doi 10285:PMC 10275:doi 10226:doi 10222:277 10187:doi 10183:283 10149:doi 10145:276 10108:doi 10067:doi 10028:doi 9991:doi 9987:277 9923:doi 9919:277 9882:doi 9878:279 9841:doi 9837:275 9800:PMC 9792:doi 9751:doi 9747:274 9710:doi 9706:277 9669:doi 9665:248 9628:doi 9624:273 9587:doi 9546:doi 9542:277 9505:PMC 9497:doi 9456:doi 9412:doi 9408:277 9371:doi 9367:274 9330:doi 9289:doi 9285:277 9245:doi 9204:doi 9200:276 9163:doi 9122:doi 9118:275 9081:doi 9040:doi 9036:278 8999:doi 8995:279 8958:doi 8917:doi 8876:PMC 8866:doi 8817:PMC 8807:doi 8758:PMC 8748:doi 8699:doi 8658:doi 8654:277 8612:PMC 8604:doi 8563:doi 8559:141 8522:PMC 8514:doi 8468:doi 8464:279 8424:PMC 8416:doi 8375:doi 8371:277 8334:doi 8330:275 8293:doi 8289:277 8252:PMC 8244:doi 8203:PMC 8195:doi 8145:doi 8110:doi 8072:doi 8068:277 8028:doi 8024:279 7987:doi 7983:278 7918:doi 7877:PMC 7869:doi 7820:hdl 7812:doi 7766:hdl 7758:doi 7754:112 7686:PMC 7678:doi 7674:375 7637:PMC 7629:doi 7588:PMC 7580:doi 7539:doi 7535:275 7471:doi 7430:doi 7374:PMC 7364:doi 7317:doi 7313:306 7275:doi 7271:273 7234:doi 7187:doi 7149:doi 7145:276 7108:doi 7104:276 7067:PMC 7057:doi 7045:101 7008:doi 7004:272 6967:PMC 6957:doi 6881:doi 6877:277 6840:doi 6799:doi 6795:278 6758:doi 6754:277 6717:doi 6671:doi 6623:doi 6619:273 6582:doi 6578:276 6541:PMC 6533:doi 6492:PMC 6482:doi 6430:PMC 6422:doi 6418:105 6381:doi 6340:PMC 6332:doi 6290:doi 6252:doi 6211:PMC 6203:doi 6138:PMC 6130:doi 6126:371 6089:PMC 6081:doi 6040:doi 6036:278 5999:PMC 5991:doi 5987:149 5950:PMC 5942:doi 5903:doi 5855:doi 5851:123 5818:doi 5774:hdl 5764:doi 5723:doi 5719:270 5682:PMC 5674:doi 5670:177 5633:PMC 5625:doi 5584:PMC 5574:doi 5562:102 5525:PMC 5515:doi 5511:296 5474:hdl 5464:doi 5460:270 5423:PMC 5415:doi 5368:doi 5331:doi 5290:PMC 5280:doi 5225:doi 5213:608 5175:PMC 5165:doi 5118:doi 5078:doi 5037:PMC 5029:doi 5025:116 4982:doi 4937:doi 4896:PMC 4888:doi 4841:doi 4837:153 4806:doi 4794:240 4761:PMC 4751:doi 4739:101 4702:PMC 4694:doi 4682:500 4645:PMC 4637:doi 4593:doi 4589:279 4552:doi 4511:PMC 4503:doi 4462:PMC 4454:doi 4413:doi 4409:275 4372:doi 4368:280 4331:doi 4290:doi 4249:PMC 4241:doi 4192:doi 4188:215 4151:doi 4112:doi 4077:doi 4040:doi 3999:doi 3960:doi 3888:doi 3851:doi 3809:doi 3766:doi 3731:doi 3686:doi 3647:doi 3609:doi 3568:doi 3529:doi 3494:doi 3362:UXT 3308:SRY 3302:Src 2944:or 2936:or 2650:85 2625:RBA 2516:or 2431:A/B 2382:kDa 2213:TSA 2209:NAD 2118:of 2032:or 1858:PDB 1452:367 650:End 549:End 452:OMA 428:MGI 48:PDB 18724:: 18641:, 18634:, 18599:, 18595:, 18591:, 18587:, 18583:, 18236:, 18232:, 18228:, 18224:, 17534:, 17189:) 16778:) 16679:) 16476:AR 16364:T1 16342:35 16337:16 16320:4A 16315:3B 16310:3A 16300:1B 16295:1A 16272:B3 16222:Rb 15977:21 15972:18 15967:15 15962:14 15957:13 15952:12 15947:11 15942:10 15890:1B 15885:1A 15704:22 15699:21 15694:19 15569:C4 15564:C3 15559:C2 15554:C1 15205:S1 15200:R2 15195:R1 15190:Q1 15185:P4 15180:P3 15175:P2 15170:P1 15165:O6 15160:O4 15155:O3 15150:O1 15145:N4 15140:N3 15135:N2 15130:N1 15125:M1 15120:L2 15115:L1 15110:K2 15105:K1 15100:J3 15095:J2 15090:J1 15085:I3 15080:I2 15075:I1 15070:H1 15065:G1 15060:F2 15055:F1 15050:E3 15045:E1 15015:D4 15010:D3 15005:D2 15000:D1 14995:C2 14990:C1 14985:B2 14980:B1 14975:A3 14970:A2 14965:A1 14918:/ 14820:2B 14815:2A 14692:11 14665:: 14646:: 14622:20 14617:17 14612:16 14607:10 14435:1B 14430:1A 14210:EN 14049:D9 14044:D8 14039:D4 14034:D3 14029:D1 14004:C9 13999:C8 13994:C6 13989:C5 13984:C4 13974:B9 13969:B8 13964:B7 13959:B6 13954:B5 13949:B4 13944:B3 13939:B2 13934:B1 13914:A9 13909:A7 13904:A5 13899:A4 13894:A3 13889:A2 13884:A1 13682:1D 13677:1C 13672:1B 13667:1A 13429:74 13424:51 13419:44 13414:43 13409:41 13404:35 13399:34 13389:24 13384:22 13379:19 13374:10 13347:40 13342:33 13337:32 13332:21 13327:20 13322:17 13317:16 13312:11 13300:7B 13295:7A 13199:SP 13192:17 13187:15 13182:14 13177:13 13172:12 13167:11 13162:10 13017:S2 13012:S1 12890:3A 12885:2I 12443:II 11797:ID 11686:3A 11676:1A 11322:L3 11317:L2 11312:L1 11238:L1 10975:: 10954:: 10936:AR 10930:AR 10788:. 10778:. 10768:22 10766:. 10762:. 10739:. 10729:. 10719:13 10717:. 10713:. 10690:. 10676:. 10672:. 10649:. 10637:16 10635:. 10631:. 10608:. 10598:. 10588:19 10586:. 10582:. 10559:. 10545:. 10541:. 10518:. 10506:68 10504:. 10500:. 10477:. 10463:. 10459:. 10436:. 10422:. 10418:. 10395:. 10385:. 10375:. 10365:96 10363:. 10359:. 10336:. 10328:. 10318:57 10316:. 10293:. 10283:. 10273:. 10263:99 10261:. 10257:. 10234:. 10220:. 10216:. 10193:. 10181:. 10157:. 10143:. 10139:. 10116:. 10104:11 10102:. 10098:. 10075:. 10063:64 10061:. 10057:. 10034:. 10024:40 10022:. 9999:. 9985:. 9981:. 9956:61 9954:. 9931:. 9917:. 9913:. 9890:. 9876:. 9872:. 9849:. 9835:. 9831:. 9808:. 9798:. 9788:18 9786:. 9782:. 9759:. 9745:. 9741:. 9718:. 9704:. 9700:. 9677:. 9663:. 9659:. 9636:. 9622:. 9618:. 9595:. 9583:29 9581:. 9577:. 9554:. 9540:. 9536:. 9513:. 9503:. 9493:24 9491:. 9487:. 9464:. 9452:18 9450:. 9446:. 9434:^ 9420:. 9406:. 9402:. 9379:. 9365:. 9361:. 9338:. 9326:14 9324:. 9320:. 9297:. 9283:. 9279:. 9267:^ 9253:. 9241:16 9239:. 9235:. 9212:. 9198:. 9194:. 9171:. 9159:21 9157:. 9153:. 9130:. 9116:. 9112:. 9089:. 9077:16 9075:. 9071:. 9048:. 9034:. 9030:. 9007:. 8993:. 8989:. 8966:. 8954:13 8952:. 8948:. 8925:. 8913:16 8911:. 8907:. 8884:. 8874:. 8864:. 8854:96 8852:. 8848:. 8825:. 8815:. 8805:. 8795:95 8793:. 8789:. 8766:. 8756:. 8746:. 8736:93 8734:. 8730:. 8707:. 8695:13 8693:. 8689:. 8666:. 8652:. 8648:. 8634:^ 8620:. 8610:. 8600:85 8598:. 8594:. 8571:. 8557:. 8553:. 8530:. 8520:. 8510:23 8508:. 8504:. 8490:^ 8476:. 8462:. 8458:. 8446:^ 8432:. 8422:. 8412:19 8410:. 8406:. 8383:. 8369:. 8365:. 8342:. 8328:. 8324:. 8301:. 8287:. 8283:. 8260:. 8250:. 8240:28 8238:. 8234:. 8211:. 8201:. 8191:25 8189:. 8185:. 8173:^ 8159:. 8151:. 8141:42 8139:. 8116:. 8106:31 8104:. 8080:. 8066:. 8062:. 8050:^ 8036:. 8022:. 8018:. 7995:. 7981:. 7977:. 7952:63 7950:. 7926:. 7912:. 7908:. 7885:. 7875:. 7865:23 7863:. 7859:. 7836:. 7828:. 7818:. 7808:69 7806:. 7782:. 7774:. 7764:. 7752:. 7748:. 7718:. 7694:. 7684:. 7672:. 7668:. 7645:. 7635:. 7625:24 7623:. 7619:. 7596:. 7586:. 7576:69 7574:. 7570:. 7547:. 7533:. 7529:. 7504:59 7502:. 7479:. 7467:24 7465:. 7461:. 7438:. 7426:15 7424:. 7420:. 7382:. 7372:. 7362:. 7352:95 7350:. 7346:. 7323:. 7311:. 7297:^ 7283:. 7269:. 7265:. 7242:. 7230:34 7228:. 7224:. 7201:. 7193:. 7183:56 7181:. 7157:. 7143:. 7139:. 7116:. 7102:. 7098:. 7075:. 7065:. 7055:. 7043:. 7039:. 7016:. 7002:. 6998:. 6975:. 6965:. 6955:. 6945:97 6943:. 6939:. 6914:60 6912:. 6889:. 6875:. 6871:. 6848:. 6836:22 6834:. 6830:. 6807:. 6793:. 6789:. 6766:. 6752:. 6748:. 6725:. 6713:18 6711:. 6707:. 6693:^ 6679:. 6667:18 6665:. 6661:. 6645:^ 6631:. 6617:. 6613:. 6590:. 6576:. 6572:. 6549:. 6539:. 6529:23 6527:. 6523:. 6500:. 6490:. 6480:. 6470:98 6468:. 6464:. 6452:^ 6438:. 6428:. 6416:. 6412:. 6389:. 6377:21 6375:. 6371:. 6348:. 6338:. 6328:39 6326:. 6322:. 6310:^ 6296:. 6286:33 6284:. 6260:. 6248:23 6246:. 6242:. 6219:. 6209:. 6199:96 6197:. 6193:. 6168:. 6146:. 6136:. 6124:. 6120:. 6097:. 6087:. 6077:17 6075:. 6071:. 6048:. 6034:. 6030:. 6007:. 5997:. 5985:. 5981:. 5958:. 5948:. 5938:36 5936:. 5932:. 5909:. 5899:66 5897:. 5885:^ 5871:. 5861:. 5826:. 5814:18 5812:. 5808:. 5796:^ 5782:. 5772:. 5760:12 5758:. 5754:. 5731:. 5717:. 5713:. 5690:. 5680:. 5668:. 5664:. 5641:. 5631:. 5621:27 5619:. 5615:. 5592:. 5582:. 5572:. 5560:. 5556:. 5533:. 5523:. 5509:. 5505:. 5482:. 5472:. 5458:. 5454:. 5431:. 5421:. 5411:51 5409:. 5405:. 5382:. 5374:. 5364:17 5362:. 5339:. 5327:27 5325:. 5321:. 5298:. 5288:. 5278:. 5268:91 5266:. 5262:. 5239:. 5231:. 5223:. 5211:. 5197:^ 5183:. 5173:. 5163:. 5153:13 5151:. 5147:. 5124:. 5114:53 5112:. 5100:^ 5086:. 5072:. 5068:. 5045:. 5035:. 5023:. 5019:. 4996:. 4988:. 4978:18 4976:. 4953:. 4945:. 4933:16 4931:. 4927:. 4904:. 4894:. 4886:. 4874:. 4870:. 4847:. 4835:. 4812:. 4804:. 4792:. 4769:. 4759:. 4749:. 4737:. 4733:. 4710:. 4700:. 4692:. 4680:. 4676:. 4653:. 4643:. 4633:26 4631:. 4627:. 4615:^ 4601:. 4587:. 4583:. 4560:. 4548:25 4546:. 4542:. 4519:. 4509:. 4499:23 4497:. 4493:. 4470:. 4460:. 4450:22 4448:. 4444:. 4421:. 4407:. 4403:. 4380:. 4366:. 4362:. 4339:. 4327:65 4325:. 4321:. 4298:. 4286:28 4284:. 4280:. 4257:. 4247:. 4237:51 4235:. 4231:. 4208:. 4200:. 4186:. 4182:. 4159:. 4147:10 4145:. 4141:. 4118:. 4108:63 4106:. 4083:. 4073:20 4071:. 4048:. 4036:27 4034:. 4030:. 4007:. 3995:16 3993:. 3989:. 3966:. 3956:41 3954:. 3929:26 3927:. 3902:. 3894:. 3884:24 3882:. 3859:. 3847:16 3845:. 3841:. 3829:^ 3815:. 3803:. 3780:. 3772:. 3762:63 3760:. 3737:. 3727:23 3725:. 3702:. 3692:. 3661:. 3653:. 3643:58 3641:. 3617:. 3603:. 3599:. 3576:. 3564:21 3562:. 3558:. 3535:. 3525:10 3523:. 3500:. 3490:16 3488:. 3469:. 3451:. 3422:^ 3401:^ 2952:, 2903:, 2899:, 2885:, 2881:, 2877:, 2873:, 2869:, 2855:, 2851:, 2847:, 2826:, 2805:, 2801:, 2797:, 2793:, 2789:, 2772:, 2768:, 2764:, 2760:, 2581:. 2426:: 2384:; 2262:AR 2223:. 2195:, 2122:. 2070:. 2036:. 2013:. 1997:, 1968:. 1909:AR 1869:; 1865:; 1848:/ 1399:/ 656:bp 643:bp 555:bp 542:bp 450:; 448:AR 446:: 442:; 440:28 438:: 434:; 430:: 426:; 422:: 407:AR 375:, 371:, 367:, 363:, 359:, 355:, 351:, 347:, 343:, 339:, 335:, 331:, 327:, 323:, 319:, 315:, 311:, 307:, 303:, 299:, 295:, 291:, 287:, 283:, 279:, 275:, 271:, 267:, 263:, 259:, 255:, 251:, 247:, 243:, 239:, 235:, 231:, 227:, 223:, 219:, 215:, 211:, 207:, 203:, 199:, 195:, 191:, 187:, 183:, 179:, 175:, 171:, 167:, 163:, 159:, 155:, 151:, 147:, 143:, 139:, 135:, 131:, 127:, 123:, 119:, 115:, 111:, 107:, 103:, 99:, 95:, 91:, 87:, 83:, 79:, 24:AR 18648:) 18644:L 18637:L 18630:L 18623:L 18603:) 18406:N 18398:N 18390:N 18290:) 18240:) 18161:N 18159:5 17538:) 17507:) 17185:( 16969:N 16965:N 16774:( 16675:( 16456:e 16449:t 16442:v 16400:/ 16391:C 16386:B 16381:A 16359:3 16354:2 16305:2 16248:/ 16194:2 16189:1 16048:4 16043:3 16038:2 16033:1 16014:4 16009:3 16004:1 15937:9 15932:8 15927:6 15922:5 15917:4 15912:3 15907:2 15902:1 15873:4 15868:3 15863:2 15858:1 15846:4 15841:3 15836:2 15831:1 15767:D 15762:C 15757:B 15752:A 15689:5 15684:3 15679:2 15674:1 15627:6 15622:5 15617:4 15612:3 15607:2 15602:1 15574:5 15468:4 15463:3 15458:2 15453:1 15418:8 15413:7 15408:6 15403:5 15398:4 15393:3 15388:2 15383:1 15366:6 15361:5 15356:4 15351:1 15329:2 15324:1 15307:4 15302:3 15297:1 15280:5 15275:4 15270:2 15245:4 15240:2 15235:1 14953:5 14948:4 14943:3 14938:2 14933:1 14899:3 14894:2 14889:1 14877:2 14872:1 14798:2 14793:1 14783:9 14778:8 14773:7 14768:6 14763:5 14758:4 14753:3 14748:2 14743:1 14714:2 14709:1 14687:7 14682:6 14672:2 14667:1 14658:C 14653:B 14648:A 14602:8 14597:6 14592:3 14587:1 14573:5 14568:4 14563:3 14558:2 14553:1 14541:2 14536:1 14524:3 14519:2 14514:1 14502:2 14497:1 14480:6 14475:5 14470:4 14465:3 14460:2 14455:1 14408:3 14403:2 14398:1 14257:2 14252:1 14220:2 14215:1 14203:2 14198:1 14184:6 14179:5 14174:4 14169:3 14164:2 14159:1 14147:2 14142:1 13849:4 13844:2 13839:1 13815:2 13810:1 13687:2 13655:4 13650:2 13645:1 13598:6 13369:9 13364:7 13359:3 13273:4 13268:3 13263:2 13258:1 13224:8 13219:7 13214:4 13209:2 13204:1 13157:9 13152:8 13147:7 13142:6 13137:5 13132:4 13127:3 13122:2 13117:1 13100:3 13095:2 13083:3 13078:2 13073:1 13061:3 13056:2 13051:1 13039:2 13034:1 13002:3 12997:2 12992:1 12970:4 12965:3 12960:2 12955:1 12923:6 12880:4 12875:2 12870:1 12860:2 12855:1 12843:2 12838:1 12804:2 12800:2 12781:3 12776:2 12771:1 12759:6 12754:5 12749:4 12744:3 12739:2 12734:1 12720:4 12595:γ 12590:β 12585:α 12556:β 12551:α 12509:4 12504:2 12492:γ 12487:β 12482:α 12465:γ 12460:α 12438:I 12436:( 12405:β 12400:α 12388:γ 12383:β 12378:α 12366:γ 12361:β 12356:α 12339:γ 12329:α 12317:β 12312:α 12290:β 12285:α 12261:) 12259:4 12210:ε 12205:δ 12200:γ 12195:β 12190:α 12160:6 12155:5 12150:4 12145:3 12140:2 12135:1 12111:) 12109:4 12102:7 12097:6 12085:9 12080:5 12075:3 12070:2 12065:1 12048:X 12043:C 12038:B 12033:A 12003:2 11998:1 11894:L 11889:2 11884:1 11872:7 11867:6 11862:5 11857:4 11852:3 11847:2 11842:1 11817:4 11812:3 11807:2 11802:1 11785:9 11780:3 11775:2 11750:2 11745:1 11728:3 11723:2 11718:1 11706:3 11701:2 11696:1 11557:2 11552:1 11513:2 11508:1 11496:3 11491:2 11486:1 11474:2 11469:1 11425:2 11420:1 11377:) 11373:( 11354:3 11349:2 11344:1 11307:2 11295:K 11290:G 11285:F 11280:B 11233:3 11228:1 11216:ζ 11211:ε 11206:δ 11201:γ 11196:β 11191:α 11169:2 11164:1 11105:7 11100:6 11095:5 11090:4 11085:3 11080:2 11075:1 11058:) 11054:( 11012:e 11005:t 10998:v 10985:. 10964:. 10943:. 10885:. 10857:. 10837:. 10796:. 10774:: 10747:. 10725:: 10698:. 10684:: 10657:. 10643:: 10616:. 10594:: 10567:. 10553:: 10526:. 10512:: 10485:. 10471:: 10444:. 10430:: 10403:. 10379:: 10371:: 10344:. 10324:: 10301:. 10277:: 10269:: 10242:. 10228:: 10201:. 10189:: 10165:. 10151:: 10124:. 10110:: 10083:. 10069:: 10042:. 10030:: 10007:. 9993:: 9966:. 9939:. 9925:: 9898:. 9884:: 9857:. 9843:: 9816:. 9794:: 9767:. 9753:: 9726:. 9712:: 9685:. 9671:: 9644:. 9630:: 9603:. 9589:: 9562:. 9548:: 9521:. 9499:: 9472:. 9458:: 9428:. 9414:: 9387:. 9373:: 9346:. 9332:: 9305:. 9291:: 9261:. 9247:: 9220:. 9206:: 9179:. 9165:: 9138:. 9124:: 9097:. 9083:: 9056:. 9042:: 9015:. 9001:: 8974:. 8960:: 8933:. 8919:: 8892:. 8868:: 8860:: 8833:. 8809:: 8801:: 8774:. 8750:: 8742:: 8715:. 8701:: 8674:. 8660:: 8628:. 8606:: 8579:. 8565:: 8538:. 8516:: 8484:. 8470:: 8440:. 8418:: 8391:. 8377:: 8350:. 8336:: 8309:. 8295:: 8268:. 8246:: 8219:. 8197:: 8167:. 8147:: 8124:. 8112:: 8088:. 8074:: 8044:. 8030:: 8003:. 7989:: 7962:. 7934:. 7920:: 7914:5 7893:. 7871:: 7844:. 7822:: 7814:: 7790:. 7768:: 7760:: 7730:. 7720:1 7702:. 7680:: 7653:. 7631:: 7604:. 7582:: 7555:. 7541:: 7514:. 7487:. 7473:: 7446:. 7432:: 7390:. 7366:: 7358:: 7331:. 7319:: 7291:. 7277:: 7250:. 7236:: 7209:. 7189:: 7165:. 7151:: 7124:. 7110:: 7083:. 7059:: 7051:: 7024:. 7010:: 6983:. 6959:: 6951:: 6924:. 6897:. 6883:: 6856:. 6842:: 6815:. 6801:: 6774:. 6760:: 6733:. 6719:: 6687:. 6673:: 6639:. 6625:: 6598:. 6584:: 6557:. 6535:: 6508:. 6484:: 6476:: 6446:. 6424:: 6397:. 6383:: 6356:. 6334:: 6304:. 6292:: 6268:. 6254:: 6227:. 6205:: 6178:. 6154:. 6132:: 6105:. 6083:: 6056:. 6042:: 6015:. 5993:: 5966:. 5944:: 5917:. 5905:: 5879:. 5857:: 5834:. 5820:: 5790:. 5776:: 5766:: 5739:. 5725:: 5698:. 5676:: 5649:. 5627:: 5600:. 5576:: 5568:: 5541:. 5517:: 5490:. 5476:: 5466:: 5439:. 5417:: 5390:. 5370:: 5347:. 5333:: 5306:. 5282:: 5274:: 5247:. 5227:: 5219:: 5191:. 5167:: 5159:: 5132:. 5120:: 5094:. 5080:: 5074:9 5053:. 5031:: 5004:. 4984:: 4961:. 4939:: 4912:. 4890:: 4882:: 4876:9 4855:. 4843:: 4820:. 4808:: 4800:: 4777:. 4753:: 4745:: 4718:. 4696:: 4688:: 4661:. 4639:: 4609:. 4595:: 4568:. 4554:: 4527:. 4505:: 4478:. 4456:: 4429:. 4415:: 4388:. 4374:: 4347:. 4333:: 4306:. 4292:: 4265:. 4243:: 4216:. 4194:: 4167:. 4153:: 4126:. 4114:: 4091:. 4079:: 4056:. 4042:: 4015:. 4001:: 3974:. 3962:: 3939:. 3910:. 3890:: 3867:. 3853:: 3823:. 3811:: 3805:8 3788:. 3768:: 3745:. 3733:: 3710:. 3688:: 3669:. 3649:: 3625:. 3611:: 3605:8 3584:. 3570:: 3543:. 3531:: 3508:. 3496:: 3473:. 3455:. 3370:. 3358:, 3352:, 3346:, 3340:, 3334:, 3328:, 3322:, 3316:, 3310:, 3304:, 3298:, 3292:, 3286:, 3280:, 3274:, 3268:, 3262:, 3256:, 3250:, 3244:, 3238:, 3232:, 3226:, 3220:, 3214:, 3208:, 3202:, 3196:, 3190:, 3184:, 3178:, 3172:, 3166:, 3160:, 3154:, 3148:, 3142:, 3136:, 3130:, 3124:, 3118:, 3112:, 3106:, 3100:, 3094:, 3088:, 3082:, 3076:, 3070:, 3064:, 3058:, 3052:, 3046:, 3040:, 3034:, 3028:, 3022:, 3016:, 3010:, 3004:, 2998:, 2992:, 2889:) 2859:) 2830:) 2809:) 2776:) 2609:e 2602:t 2595:v 2532:F 2504:E 2495:D 2480:C 2424:F 2420:A 2399:. 2371:B 2367:A 1907:( 574:) 471:) 454::

Index


PDB
PDBe
RCSB
1E3G
1GS4
1T5Z
1T63
1T65
1XJ7
1XOW
1XQ3
1Z95
2AM9
2AMA
2AMB
2AO6
2AX6
2AX7
2AX8
2AX9
2AXA
2HVC
2OZ7
2PIO
2PIP
2PIQ
2PIR
2PIT
2PIU

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.