651:
628:
40:
31:
2718:
867:
Irbesartan is used for the treatment of hypertension. It may also delay progression of diabetic nephropathy and is also indicated for the reduction of renal disease progression in patients with type 2 diabetes, hypertension and microalbuminuria (>30 mg/24 h) or proteinuria
1582:
1460:
1043:
1550:
1572:
1822:
2043:
1952:
1979:
1648:
1852:
1818:
1814:
271:
1452:
1035:
1542:
1641:
759:
InChI=1S/C25H28N6O/c1-2-3-10-22-26-25(15-6-7-16-25)24(32)31(22)17-18-11-13-19(14-12-18)20-8-4-5-9-21(20)23-27-29-30-28-23/h4-5,8-9,11-14H,2-3,6-7,10,15-17H2,1H3,(H,27,28,29,30)
1149:
1634:
2278:
2076:
1723:
1948:
1806:
1727:
717:
1975:
1744:
1707:
2060:
1996:
1860:
1856:
1848:
1762:
216:
1604:
2748:
1520:
1490:
2434:
2424:
2409:
2399:
2271:
2165:
104:
2738:
2637:
2622:
2607:
2459:
2429:
2419:
2364:
731:
2617:
2612:
2359:
2155:
1182:
2642:
2414:
2374:
1073:
2685:
2017:
2695:
2264:
2120:
2068:
1141:
2222:
1376:"Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes"
1352:
1322:
1265:
1116:
984:
928:
1926:
841:
1626:
776:
155:
1436:
1298:
1241:
751:
2239:
2047:
405:
256:
136:
2773:
2021:
1983:
1907:
1784:
2690:
2137:
2116:
2072:
1835:
1714:
1427:
476:
2000:
1890:
1661:
1546:
934:
646:
527:
1685:
1007:"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)"
607:
2708:
596:
855:. In 2021, it was the 172nd most commonly prescribed medication in the United States, with more than 3
1512:
1006:
1482:
2768:
623:
2227:
1543:"Recalls of Angiotensin II Receptor Blockers (ARBs) including Valsartan, Losartan and Irbesartan"
802:
192:
94:
2039:
1883:
1810:
1802:
877:
340:
1453:"Prescription medicines: registration of new generic medicines and biosimilar medicines, 2017"
1288:
1204:
1174:
1036:"Prescription medicines: registration of new generic medicines and biosimilar medicines, 2017"
937:(FDA) reported that some versions of the angiotensin II receptor blocker medicines (including
2680:
2013:
1780:
1740:
1657:
576:
467:
1374:
Lewis EJ, Hunsicker LG, Clarke WR, Berl T, Pohl MA, Lewis JB, et al. (September 2001).
1065:
851:
Irbesartan was patented in 1990, and approved for medical use in 1997. It is available as a
431:
2675:
2298:
2287:
2191:
2112:
2084:
2064:
906:
536:
367:
516:
8:
2753:
2080:
881:
810:
422:
199:
650:
627:
2758:
2290:
1656:
852:
825:
166:
1432:
1407:
1294:
1237:
885:
284:
128:
2763:
1397:
1387:
663:
322:
239:
229:
57:
2256:
1344:
1314:
1257:
1108:
976:
956:
The FDA issued revised guidelines about nitrosamine impurities in
September 2024.
114:
2743:
2722:
2652:
2319:
2095:
821:
456:
350:
330:
39:
2324:
2314:
2233:
902:
845:
2732:
2657:
1674:
1577:
950:
924:
837:
798:
639:
297:
805:. It is a reasonable initial treatment for high blood pressure. It is taken
2592:
2582:
2562:
2512:
2150:
1876:
1665:
1411:
794:
234:
224:
22:
2572:
2547:
2537:
2532:
2502:
2449:
2354:
2344:
2160:
2032:
1941:
1795:
1392:
1375:
946:
817:
122:
496:
2587:
2577:
2557:
2522:
2507:
2487:
2477:
2444:
2439:
2404:
2384:
2379:
2369:
2349:
2208:
2184:
2175:
2141:
2027:
2006:
1963:
1958:
1936:
1900:
1895:
1871:
1773:
1750:
1733:
1700:
1695:
1402:
910:
829:
693:
507:
206:
30:
2632:
2627:
2602:
2567:
2542:
2527:
2517:
2497:
2482:
2472:
2454:
2334:
2329:
2126:
2105:
2053:
1916:
1866:
1828:
1790:
1768:
1719:
1690:
938:
833:
442:
380:
108:
2552:
2492:
2394:
1989:
1841:
1755:
942:
806:
556:
487:
150:
1483:"Irbesartan and Hydrochlorothiazide (Professional Patient Advice)"
716:
1513:"Irbesartan and hydrochlorothiazide Advanced Patient Information"
1142:"Avalide- irbesartan and hydrochlorothiazide tablet, film coated"
816:
Common side effects include dizziness, diarrhea, feeling tired,
587:
385:
359:
81:
707:
567:
389:
355:
612:
75:
60:
547:
66:
1014:
413:
2-butyl-3-({4-phenyl}methyl)-1,3-diazaspironon-1-en-4-one
1373:
1236:(76 ed.). Pharmaceutical Press. 2018. p. 175.
809:. Versions are available as the combination irbesartan/
2706:
2467:
971:
969:
72:
78:
63:
2286:
1136:
1134:
999:
739:
O=C1N(\C(=N/C12CCCC2)CCCC)Cc5ccc(c3ccccc3c4nnn4)cc5
475:
69:
1605:"Control of Nitrosamine Impurities in Human Drugs"
966:
888:, to achieve an additive antihypertensive effect.
820:, and heartburn. Serious side effects may include
1573:"Nitrosamine impurities in medications: Guidance"
1258:"Irbesartan Pregnancy and Breastfeeding Warnings"
1115:. American Society of Health-System Pharmacists.
2730:
1169:
1167:
1131:
945:, irbesartan and other "-sartan" drugs) contain
905:). It is jointly marketed by Sanofi-Aventis and
455:
1286:
430:
929:Angiotensin II receptor blocker § recalls
2272:
1642:
1164:
901:It was developed by Sanofi Research (part of
2299:
871:
793:among others, is a medication used to treat
154:
1431:. Adelaide: Australian Medicines Handbook.
314:In general: ℞ (Prescription only)
2279:
2265:
1649:
1635:
1367:
1103:
1101:
1099:
1097:
1095:
1093:
1091:
977:"Irbesartan (Avapro) Use During Pregnancy"
649:
626:
515:
38:
29:
2686:Olmesartan/amlodipine/hydrochlorothiazide
1418:
1401:
1391:
535:
2696:Valsartan/hydrochlorothiazide/amlodipine
1250:
1234:British national formulary : BNF 76
1109:"Irbesartan Monograph for Professionals"
2749:Drugs developed by Bristol Myers Squibb
1823:+bisoprolol, amlodipine, and indapamide
1280:
1228:
1226:
1088:
622:
495:
127:
2731:
1457:Therapeutic Goods Administration (TGA)
1293:. John Wiley & Sons. p. 470.
1040:Therapeutic Goods Administration (TGA)
953:also reported nitrosamine impurities.
891:
640:
306:
278:
2260:
1630:
1424:
1152:from the original on 15 February 2018
1119:from the original on 30 November 2019
844:and works by blocking the effects of
595:
575:
291:
145:
113:
1553:from the original on 13 October 2023
1345:"Irbesartan - Drug Usage Statistics"
1325:from the original on 15 January 2024
1223:
238:
228:
2739:Angiotensin II receptor antagonists
1380:The New England Journal of Medicine
555:
446:
13:
1523:from the original on 20 March 2020
1493:from the original on 20 March 2020
1355:from the original on 11 April 2020
876:Irbesartan is also available in a
842:angiotensin II receptor antagonist
14:
2785:
1609:U.S. Food and Drug Administration
1185:from the original on 13 June 2024
1076:from the original on 13 June 2024
265:
177:
2716:
1585:from the original on 1 June 2024
1463:from the original on 6 July 2023
1046:from the original on 6 July 2023
680:
674:
56:
1597:
1565:
1535:
1505:
1475:
1445:
1337:
1307:
1287:Fischer J, Ganellin CR (2006).
1268:from the original on 2 May 2019
1209:European Medicines Agency (EMA)
987:from the original on 2 May 2019
862:
836:may harm the baby and use when
764:Key:YOSHYTLCDANDAN-UHFFFAOYSA-N
1197:
1058:
1028:
896:
686:
668:
1:
2691:Valsartan/hydrochlorothiazide
1428:Australian Medicines Handbook
1290:Analogue-based Drug Discovery
959:
913:Aprovel, Karvea, and Avapro.
868:(>900 mg/24 h).
840:is not recommended. It is an
2304:Tooltip Angiotensin receptor
1547:Food and Drug Administration
935:Food and Drug Administration
789:, sold under the brand name
7:
10:
2790:
1819:+bisoprolol and amlodipine
1815:+amlodipine and indapamide
922:
916:
658:Chemical and physical data
2666:
2297:
2217:
2201:
2174:
2135:
2094:
1925:
1673:
1179:European Medicines Agency
1070:European Medicines Agency
872:Combination with diuretic
772:
747:
727:
705:
692:
662:
657:
638:
606:
586:
566:
546:
526:
506:
486:
466:
441:
421:
401:
396:
379:
366:
349:
339:
329:
321:
255:
250:
215:
205:
191:
165:
135:
121:
103:
93:
51:
46:
37:
28:
1715:Dicarboxylate-containing
1662:renin–angiotensin system
925:Valsartan § recalls
859:million prescriptions.
803:diabetic kidney disease
99:Aprovel, Avapro, others
1891:Phosphonate-containing
1658:Antihypertensive drugs
878:fixed-dose combination
2774:Nitrogen heterocycles
2681:Olmesartan/amlodipine
1686:Sulfhydryl-containing
1425:Rossi S, ed. (2006).
1315:"The Top 300 of 2021"
2676:Amlodipine/valsartan
2288:Angiotensin receptor
1549:(FDA). 10 May 2021.
1519:. 24 December 2019.
1393:10.1056/NEJMoa011303
907:Bristol-Myers Squibb
211:Cardiovascular agent
2121:+amlodipine and HCT
2069:+amlodipine and HCT
2044:+amlodipine and HCT
2018:+amlodipine and HCT
1980:+amlodipine and HCT
1953:+amlodipine and HCT
1853:+amlodipine and HCT
1181:. 15 October 1998.
892:Society and culture
882:hydrochlorothiazide
811:hydrochlorothiazide
795:high blood pressure
287:(Prescription only)
274:(Prescription only)
25:
2244:Never to phase III
1611:. 24 February 2021
1072:. 27 August 1997.
983:. 16 August 2018.
853:generic medication
826:low blood pressure
21:
2704:
2703:
2600:Renin inhibitors:
2254:
2253:
1211:. 16 October 1998
886:thiazide diuretic
880:formulation with
784:
783:
718:Interactive image
608:CompTox Dashboard
310:
295:
282:
269:
181:
148:
16:Chemical compound
2781:
2721:
2720:
2719:
2712:
2469:
2305:
2301:
2281:
2274:
2267:
2258:
2257:
2189:
2110:
2096:Renin inhibitors
2058:
2037:
2011:
1994:
1973:
1946:
1914:Other/ungrouped:
1905:
1881:
1846:
1833:
1800:
1778:
1760:
1738:
1705:
1651:
1644:
1637:
1628:
1627:
1621:
1620:
1618:
1616:
1601:
1595:
1594:
1592:
1590:
1581:. 4 April 2022.
1569:
1563:
1562:
1560:
1558:
1539:
1533:
1532:
1530:
1528:
1509:
1503:
1502:
1500:
1498:
1479:
1473:
1472:
1470:
1468:
1459:. 21 June 2022.
1449:
1443:
1442:
1422:
1416:
1415:
1405:
1395:
1371:
1365:
1364:
1362:
1360:
1341:
1335:
1334:
1332:
1330:
1311:
1305:
1304:
1284:
1278:
1277:
1275:
1273:
1254:
1248:
1247:
1230:
1221:
1220:
1218:
1216:
1205:"Karvezide EPAR"
1201:
1195:
1194:
1192:
1190:
1175:"CoAprovel EPAR"
1171:
1162:
1161:
1159:
1157:
1148:. 31 July 2018.
1138:
1129:
1128:
1126:
1124:
1105:
1086:
1085:
1083:
1081:
1062:
1056:
1055:
1053:
1051:
1042:. 21 June 2022.
1032:
1026:
1025:
1023:
1021:
1011:nctr-crs.fda.gov
1003:
997:
996:
994:
992:
973:
933:In 2018, the US
858:
780:
779:
720:
700:
688:
682:
676:
670:
653:
642:
631:
630:
616:
614:
599:
579:
559:
539:
519:
499:
479:
459:
449:
448:
434:
371:
308:
305:
300:
293:
290:
280:
277:
267:
264:
242:
232:
179:
176:
158:
147:
144:
131:
117:
88:
87:
84:
83:
80:
77:
74:
71:
68:
65:
62:
42:
33:
26:
24:
20:
2789:
2788:
2784:
2783:
2782:
2780:
2779:
2778:
2769:Spiro compounds
2729:
2728:
2727:
2717:
2715:
2707:
2705:
2700:
2662:
2653:Angiotensinogen
2320:Angiotensin III
2303:
2293:
2285:
2255:
2250:
2249:
2234:Clinical trials
2213:
2197:
2187:
2170:
2131:
2108:
2098:
2090:
2056:
2035:
2009:
1992:
1971:
1944:
1929:
1921:
1903:
1879:
1844:
1831:
1798:
1776:
1758:
1736:
1703:
1677:
1669:
1655:
1625:
1624:
1614:
1612:
1603:
1602:
1598:
1588:
1586:
1571:
1570:
1566:
1556:
1554:
1541:
1540:
1536:
1526:
1524:
1511:
1510:
1506:
1496:
1494:
1489:. 5 June 2019.
1481:
1480:
1476:
1466:
1464:
1451:
1450:
1446:
1439:
1423:
1419:
1386:(12): 851–860.
1372:
1368:
1358:
1356:
1343:
1342:
1338:
1328:
1326:
1313:
1312:
1308:
1301:
1285:
1281:
1271:
1269:
1256:
1255:
1251:
1244:
1232:
1231:
1224:
1214:
1212:
1203:
1202:
1198:
1188:
1186:
1173:
1172:
1165:
1155:
1153:
1140:
1139:
1132:
1122:
1120:
1107:
1106:
1089:
1079:
1077:
1064:
1063:
1059:
1049:
1047:
1034:
1033:
1029:
1019:
1017:
1005:
1004:
1000:
990:
988:
975:
974:
967:
962:
931:
919:
899:
894:
874:
865:
856:
822:kidney problems
775:
773:
768:
765:
760:
755:
754:
743:
740:
735:
734:
723:
698:
685:
679:
673:
634:
610:
602:
582:
562:
542:
522:
502:
482:
462:
445:
437:
417:
414:
409:
408:
369:
341:Protein binding
331:Bioavailability
323:Pharmacokinetic
317:
298:
246:
194:
187:
168:
161:
59:
55:
17:
12:
11:
5:
2787:
2777:
2776:
2771:
2766:
2761:
2756:
2751:
2746:
2741:
2726:
2725:
2702:
2701:
2699:
2698:
2693:
2688:
2683:
2678:
2672:
2670:
2664:
2663:
2661:
2660:
2655:
2646:
2645:
2640:
2635:
2630:
2625:
2620:
2615:
2610:
2605:
2596:
2595:
2590:
2585:
2580:
2575:
2570:
2565:
2560:
2555:
2550:
2545:
2540:
2535:
2530:
2525:
2520:
2515:
2510:
2505:
2500:
2495:
2490:
2485:
2480:
2475:
2463:
2462:
2457:
2452:
2447:
2442:
2437:
2432:
2427:
2422:
2417:
2412:
2407:
2402:
2397:
2392:
2387:
2382:
2377:
2372:
2367:
2362:
2357:
2352:
2347:
2338:
2337:
2332:
2327:
2325:Angiotensin IV
2322:
2317:
2315:Angiotensin II
2308:
2306:
2295:
2294:
2284:
2283:
2276:
2269:
2261:
2252:
2251:
2248:
2247:
2246:
2245:
2242:
2231:
2225:
2219:
2218:
2215:
2214:
2212:
2211:
2205:
2203:
2199:
2198:
2196:
2195:
2181:
2179:
2172:
2171:
2169:
2168:
2163:
2158:
2153:
2147:
2145:
2133:
2132:
2130:
2129:
2124:
2102:
2100:
2092:
2091:
2089:
2088:
2077:+lercanidipine
2051:
2030:
2025:
2004:
1987:
1966:
1961:
1956:
1939:
1933:
1931:
1923:
1922:
1920:
1919:
1911:
1898:
1887:
1874:
1869:
1864:
1839:
1826:
1793:
1788:
1771:
1766:
1753:
1748:
1731:
1724:+lercanidipine
1711:
1698:
1693:
1681:
1679:
1675:ACE inhibitors
1671:
1670:
1660:acting on the
1654:
1653:
1646:
1639:
1631:
1623:
1622:
1596:
1564:
1534:
1504:
1474:
1444:
1437:
1417:
1366:
1336:
1306:
1299:
1279:
1249:
1242:
1222:
1196:
1163:
1130:
1087:
1066:"Aprovel EPAR"
1057:
1027:
998:
964:
963:
961:
958:
918:
915:
903:Sanofi-Aventis
898:
895:
893:
890:
873:
870:
864:
861:
846:angiotensin II
782:
781:
770:
769:
767:
766:
763:
761:
758:
750:
749:
748:
745:
744:
742:
741:
738:
730:
729:
728:
725:
724:
722:
721:
713:
711:
703:
702:
696:
690:
689:
683:
677:
671:
666:
660:
659:
655:
654:
644:
636:
635:
633:
632:
619:
617:
604:
603:
601:
600:
592:
590:
584:
583:
581:
580:
572:
570:
564:
563:
561:
560:
552:
550:
544:
543:
541:
540:
532:
530:
524:
523:
521:
520:
512:
510:
504:
503:
501:
500:
492:
490:
484:
483:
481:
480:
472:
470:
464:
463:
461:
460:
452:
450:
439:
438:
436:
435:
427:
425:
419:
418:
416:
415:
412:
404:
403:
402:
399:
398:
394:
393:
383:
377:
376:
373:
364:
363:
353:
347:
346:
343:
337:
336:
333:
327:
326:
319:
318:
316:
315:
312:
303:
288:
275:
261:
259:
253:
252:
248:
247:
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2668:Combinations:
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2658:Angiotensin I
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2186:
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2182:
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2173:
2167:
2164:
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2157:
2154:
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2146:
2143:
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2103:
2101:
2097:
2093:
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2078:
2074:
2070:
2066:
2062:
2055:
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2049:
2045:
2041:
2034:
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2029:
2026:
2023:
2019:
2015:
2008:
2005:
2002:
1998:
1991:
1988:
1985:
1981:
1977:
1970:
1967:
1965:
1962:
1960:
1957:
1954:
1950:
1943:
1940:
1938:
1935:
1934:
1932:
1928:
1924:
1918:
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1767:
1764:
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1729:
1728:+nitrendipine
1725:
1721:
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1578:Health Canada
1574:
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1438:0-9757919-2-3
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951:Health Canada
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838:breastfeeding
835:
831:
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819:
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804:
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762:
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712:
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697:
695:
691:
667:
665:
661:
656:
652:
648:
645:
643:
641:ECHA InfoCard
637:
629:
625:
624:DTXSID0023169
621:
620:
618:
609:
605:
598:
594:
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591:
589:
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578:
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365:
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328:
324:
320:
313:
311: Rx-only
304:
301:
289:
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263:
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98:
96:
92:
86:
54:
52:Pronunciation
50:
47:Clinical data
45:
41:
36:
32:
27:
19:
2667:
2650:Propeptides:
2649:
2599:
2593:Zofenoprilat
2583:Trandolapril
2563:Rescinnamine
2513:Gemopatrilat
2466:
2389:
2342:Antagonists:
2341:
2311:
2151:Gemopatrilat
1968:
1913:
1889:
1877:Trandolapril
1713:
1684:
1613:. Retrieved
1608:
1599:
1587:. Retrieved
1576:
1567:
1555:. Retrieved
1537:
1525:. Retrieved
1516:
1507:
1495:. Retrieved
1486:
1477:
1465:. Retrieved
1456:
1447:
1426:
1420:
1383:
1379:
1369:
1357:. Retrieved
1348:
1339:
1327:. Retrieved
1318:
1309:
1289:
1282:
1270:. Retrieved
1261:
1252:
1233:
1213:. Retrieved
1208:
1199:
1187:. Retrieved
1178:
1154:. Retrieved
1145:
1121:. Retrieved
1112:
1078:. Retrieved
1069:
1060:
1048:. Retrieved
1039:
1030:
1018:. Retrieved
1010:
1001:
989:. Retrieved
980:
955:
949:impurities.
932:
920:
900:
875:
866:
863:Medical uses
850:
815:
790:
786:
785:
774:
375:11 h to 15 h
368:Elimination
257:Legal status
251:Legal status
137:License data
18:
2573:Spiraprilat
2548:Quinaprilat
2538:Perindopril
2533:Omapatrilat
2503:Enalaprilat
2470:inhibitors:
2450:Telmisartan
2435:Saprisartan
2425:Pratosartan
2410:Olodanrigan
2400:Milfasartan
2355:Candesartan
2345:Abitesartan
2230:from market
2166:Sampatrilat
2161:Omapatrilat
2113:+amlodipine
2085:+sacubitril
2065:+amlodipine
2040:+amlodipine
2033:Telmisartan
2014:+amlodipine
1997:+amlodipine
1976:+amlodipine
1949:+amlodipine
1942:Candesartan
1930:("-sartan")
1861:+felodipine
1857:+bisoprolol
1849:+amlodipine
1811:+indapamide
1807:+bisoprolol
1803:+amlodipine
1796:Perindopril
1781:+amlodipine
1763:+manidipine
1745:+pimobendan
1741:+amlodipine
1615:6 September
1403:2445/122787
947:nitrosamine
911:brand names
897:Brand names
818:muscle pain
701: g·mol
647:100.119.966
432:138402-11-6
397:Identifiers
123:MedlinePlus
95:Trade names
2754:Tetrazoles
2733:Categories
2638:Terlakiren
2623:Imarikiren
2608:Ciprokiren
2588:Zofenopril
2578:Temocapril
2558:Rentiapril
2523:Lisinopril
2508:Fosinopril
2488:Cilazapril
2478:Benazepril
2460:Zolasartan
2445:Tasosartan
2440:Sparsentan
2430:Ripisartan
2420:Pomisartan
2405:Olmesartan
2390:Irbesartan
2385:Forasartan
2380:Fimasartan
2370:Eprosartan
2365:Embusartan
2350:Azilsartan
2291:modulators
2209:Sparsentan
2192:+valsartan
2185:Sacubitril
2178:inhibitors
2176:Neprilysin
2144:inhibitors
2099:("-kiren")
2081:+nebivolol
2061:+aliskiren
2028:Tasosartan
2007:Olmesartan
1969:Irbesartan
1964:Fimasartan
1959:Eprosartan
1937:Azilsartan
1901:Fosinopril
1896:Ceronapril
1884:+verapamil
1872:Temocapril
1774:Lisinopril
1751:Cilazapril
1734:Benazepril
1708:+nebivolol
1701:Zofenopril
1696:Rentiapril
1557:30 January
1359:14 January
1329:14 January
1020:22 October
960:References
923:See also:
909:under the
830:angioedema
787:Irbesartan
706:3D model (
694:Molar mass
597:ChEMBL1513
577:CHEBI:5959
537:J0E2756Z7N
508:ChemSpider
468:IUPHAR/BPS
423:CAS Number
406:IUPAC name
351:Metabolism
335:60% to 80%
207:Drug class
156:Irbesartan
23:Irbesartan
2759:Biphenyls
2633:Remikiren
2628:Pepstatin
2618:Enalkiren
2613:Ditekiren
2603:Aliskiren
2568:Spirapril
2543:Quinapril
2528:Moexipril
2518:Imidapril
2498:Enalapril
2483:Captopril
2473:Alacepril
2455:Valsartan
2360:Elisartan
2335:Saralasin
2330:L-163,491
2312:Agonists:
2240:Phase III
2228:Withdrawn
2156:Ilepatril
2127:Remikiren
2106:Aliskiren
2054:Valsartan
1917:Alacepril
1867:Spirapril
1829:Quinapril
1791:Moexipril
1769:Imidapril
1720:Enalapril
1691:Captopril
1678:("-pril")
1517:Drugs.com
1487:Drugs.com
1262:Drugs.com
1215:30 August
1113:Drugs.com
981:Drugs.com
939:valsartan
834:pregnancy
832:. Use in
381:Excretion
370:half-life
193:Routes of
167:Pregnancy
115:Monograph
109:Drugs.com
2723:Medicine
2643:Zankiren
2553:Ramipril
2493:Delapril
2415:PD123319
2395:Losartan
2375:EXP-3174
1990:Losartan
1842:Ramipril
1756:Delapril
1589:24 April
1583:Archived
1551:Archived
1527:19 March
1521:Archived
1497:19 March
1491:Archived
1467:30 March
1461:Archived
1412:11565517
1353:Archived
1349:ClinCalc
1323:Archived
1319:ClinCalc
1266:Archived
1183:Archived
1156:19 March
1150:Archived
1146:DailyMed
1117:Archived
1074:Archived
1050:30 March
1044:Archived
991:19 March
985:Archived
943:losartan
807:by mouth
777:(verify)
488:DrugBank
217:ATC code
200:By mouth
169:category
151:DailyMed
2764:Lactams
1545:. U.S.
1272:3 March
1189:13 June
1123:3 March
1080:13 June
917:Recalls
791:Aprovel
699:428.540
664:Formula
497:DB01029
443:PubChem
302:Rx-only
299:WARNING
237: (
235:C09DA04
233:)
227: (
225:C09CA04
182: D
153::
129:a698009
2744:Sanofi
2709:Portal
2223:WHO-EM
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1927:AIIRAs
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1240:
927:, and
857:
828:, and
801:, and
732:SMILES
588:ChEMBL
557:D00523
386:Kidney
360:CYP2C9
296:
283:
270:
149:
89:
2202:Other
2136:Dual
752:InChI
708:JSmol
568:ChEBI
390:feces
388:20%,
356:Liver
2117:+HCT
2073:+HCT
2048:+HCT
2022:+HCT
2001:+HCT
1984:+HCT
1908:+HCT
1836:+HCT
1785:+HCT
1617:2024
1591:2023
1559:2023
1529:2020
1499:2020
1469:2024
1433:ISBN
1408:PMID
1361:2024
1331:2024
1295:ISBN
1274:2019
1238:ISBN
1217:2024
1191:2024
1158:2020
1125:2019
1082:2024
1052:2024
1022:2023
993:2020
884:, a
548:KEGG
528:UNII
517:3618
457:3749
345:~90%
325:data
105:AHFS
2468:ACE
2300:ATR
2142:NEP
2138:ACE
1666:C09
1398:hdl
1388:doi
1384:345
1015:FDA
613:EPA
477:589
447:CID
392:65%
285:POM
240:WHO
230:WHO
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
