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Resting state fMRI

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distributed neuronal groups and areas. This applies to both resting state and task-state studies. While functional connectivity can refer to correlations across subjects, runs, blocks, trials, or individual time points, resting state functional connectivity focuses on connectivity assessed across individual BOLD time points during resting conditions. Functional connectivity has also been evaluated using the perfusion time series sampled with arterial spin labeled perfusion fMRI. Functional connectivity MRI (fcMRI), which can include resting state fMRI and task-based MRI, might someday help provide more definitive diagnoses for mental health disorders such as
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easier to define ROI's and measure connectivity. In 2021, Yeung and colleagues conducted a regional analysis utilizing a modified version of the Human Connectome Project (HCP) atlas, and found changes in the functional connectome of stroke patients during rehabilitative treatment. Overall connectivity between an ROI (such as the prefrontal cortex) and all other voxels of the brain can also be averaged, providing a measure of global brain connectivity (GBC) specific to that ROI. Other methods for characterizing resting-state networks include partial correlation, coherence and partial coherence, phase relationships,
51: 310:(DMN) is a network of brain regions that are active when an individual is awake and at rest. The default mode network is an interconnected and anatomically defined brain system that preferentially activates when individuals focus on internal tasks such as daydreaming, envisioning the future, retrieving memories, and gauging others' perspectives. It is negatively correlated with brain systems that focus on external visual signals. It is one of the most studied networks present during resting state and is one of the most easily visualized networks. 148: 480:
task. This is then bolstered through structural DWI data, which shows how individual white matter tracts connect these ROI's. Investigations harnessing these techniques have progressed the field of network neuroscience, by further defining groups of regions in the brain which connect both structurally (having white matter tracts pass between them), and functionally (showing similar or opposite patterns of activity over time), into brain networks like the
411:(ICA) is a useful statistical approach in the detection of resting state networks. ICA separates a signal into non-overlapping spatial and time components. It is highly data-driven and allows for better removal of noisy components of the signal (motion, scanner drift, etc.). It also has been shown to reliably extract default mode network as well as many other networks with very high consistency. ICA remains in the forefront of the research methods. 139:. Because of the resting state aspect of this imaging, data can be collected from a range of patient groups including people with intellectual disabilities, pediatric groups, and even those that are unconscious. Resting-state functional connectivity research has revealed a number of networks which are consistently found in healthy subjects, different stages of consciousness and across species, and represent specific patterns of synchronous activity. 52: 53: 293: 232:, and discovered that the brain, even during rest, contains information about its functional organization. He had used fMRI to study how different regions of the brain communicate while the brain is at rest and not performing any active task. Though at the time, Biswal's research was mostly disregarded and attributed to another signal source, his resting neuroimaging technique has now been widely replicated and considered a valid method of 55: 539:
controls in the direction of hypothesized effects, for example a lower coherence might be found in the default network in the patient group, while the patient groups also moved more during the scan. Also, it has been shown that the use of global signal regression can produce artificial correlations between a small number of signals (e.g., two or three). Fortunately, the brain has many signals.
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usually tried to be removed during processing of the raw fMRI data. Due to these sources of noise, there have been many experts who have approached the idea of resting state fMRI very skeptically during the early uses of fMRI. It has only been very recently that researchers have become confident that the signal being measured is not an artifact caused by other physiological function.
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mental work (the resting state). His lab has been primarily focused on finding the basis of this resting activity and is credited with many groundbreaking discoveries. These include the relative independence of blood flow and oxygen consumption during changes in brain activity, which provided the physiological basis of fMRI, as well the discovery of the well known
500:(EEG) should be used simultaneously. This dual technique combines the EEG's well documented ability to characterize certain brain states with high temporal resolution and to reveal pathological patterns, with fMRI's (more recently discovered and less well understood) ability to image blood dynamics through the entire brain with high spatial resolution. Up to now, 520:(TMS) uses small and relatively precise magnetic fields to stimulate regions of the cortex without dangerous invasive procedures. When these magnetic fields stimulate an area of the cortex, focal blood flow increases at the site of stimulation as well as at distant sites anatomically connected to the stimulated location. 650:
Other types of current and future clinical applications for resting state fMRI include identifying group differences in brain disease, obtaining diagnostic and prognostic information, longitudinal studies and treatment effects, clustering in heterogeneous disease states, and pre-operative mapping and
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or cluster of voxels known as the seed or ROI are used to calculate correlations with other voxels of the brain. This provides a much more precise and detailed look at specific connectivity in brain areas of interest. This can also be performed across the entire brain by utilizing an atlas, making it
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and other groups showed that the brain's energy consumption is increased by less than 5% of its baseline energy consumption while performing a focused mental task. These experiments showed that the brain is constantly active with a high level of activity even when the person is not engaged in focused
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This combined data provides unique clinical and neuropsychiatric benefit, by enabling the investigation of how brain networks are disturbed, or white matter pathways compromised, by the presence of mental illness or structural damage. Altered brain network connectivity has been shown across a swathe
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network. As already reported, these resting-state networks consist of anatomically separated, but functionally connected regions displaying a high level of correlated BOLD signal activity. These networks are found to be quite consistent across studies, despite differences in the data acquisition and
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is assumed to last over 10 seconds, rising multiplicatively (that is, as a proportion of current value), peaking at 4 to 6 seconds, and then falling multiplicatively. Changes in the blood-flow system, the vascular system, integrate responses to neuronal activity over time. Because this response is a
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as well as evaluate the effect of treatment. Functional connectivity has been suggested to be an expression of the network behavior underlying high level cognitive function partially because unlike structural connectivity, functional connectivity often changes on the order of seconds as in the case
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Potential pitfalls when using rsfMRI to determine functional network integrity are contamination of the BOLD signal by sources of physiological noise such as heart rate, respiration, and head motion. These confounding factors can often bias results in studies where patients are compared to healthy
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While fMRI strives to measure the neuronal activity in the brain, the BOLD signal can be influenced by many other physiological factors other than neuronal activity. For example, respiratory fluctuations and cardiovascular cycles affect the BOLD signal being measured in the brain and therefore are
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structural information about the brain, these two imaging techniques are commonly used in conjunction to provide a holistic view of brain network interactions. When collected from defined ROI's, fMRI data informs researchers of how activity (blood flow) in the brain changes over time or during a
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Study showing four functional networks that were found to be highly consistent across subjects. These modules include the visual (yellow), sensory/motor (orange) and basal ganglia (red) cortices as well as the default mode network (posterior cingulate, inferior parietal lobes, and medial frontal
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The procedure is similar to MRI but uses the change in magnetization between oxygen-rich and oxygen-poor blood as its basic measure. This measure is frequently corrupted by noise from various sources and hence statistical procedures are used to extract the underlying signal. The resulting brain
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The clinical value of these findings is the subject of ongoing investigations, but recent researches suggest an acceptable reliability for EEG-fMRI studies and better sensitivity in higher field scanner. Outside the field of epilepsy, EEG-fMRI has been used to study event-related (triggered by
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Functional connectivity is the connectivity between brain regions that share functional properties. More specifically, it can be defined as the temporal correlation between spatially remote neurophysiological events, expressed as deviation from statistical independence across these events in
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activation can be presented graphically by color-coding the strength of activation across the brain or the specific region studied. The technique can localize activity to within millimeters but, using standard techniques, no better than within a window of a few seconds.
54: 524:(PET) can then be used to image the brain and changes in blood flow and results show very similar regions of connectivity confirming networks found in fMRI studies and TMS can also be used to support and provide more detailed information on the connected regions. 130:
is intrinsic, present even in the absence of an externally prompted task, any brain region will have spontaneous fluctuations in BOLD signal. The resting state approach is useful to explore the brain's functional organization and to examine if it is altered in
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Subbaraju V, Suresh MB, Sundaram S, Narasimhan S (January 2017). "Identifying differences in brain activities and an accurate detection of autism spectrum disorder using resting state functional-magnetic resonance imaging : A spatial filtering approach".
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has been mainly seen as an fMRI technique in which the synchronously acquired EEG is used to characterize brain activity ('brain state') across time allowing to map (through statistical parametric mapping, for example) the associated haemodynamic changes.
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targeting intervention. Due to its lack of reliance on task performance and cognitive demands, resting state fMRI can be a useful tool in assessing brain alterations in disorders of impaired consciousness and cognition, as well as paediatric populations.
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to characterize inter-individual differences in normal brain function, mind-brain associations, and the various disorders. This suggests reliability and reproducibility for commonly used rfMRI-derived measures of the human brain functional
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This image is from a study using both fMRI and EEG acquisition at the resting state. The left row shows sagittal, coronal and horizontal slices of the ten RSNs. On the right side the covariance and t-maps for the 8 frequency bands are
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Bartolomei F, Bosma I, Klein M, Baayen JC, Reijneveld JC, Postma TJ, et al. (September 2006). "Disturbed functional connectivity in brain tumour patients: evaluation by graph analysis of synchronization matrices".
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These fMRI images are from a study showing parts of the brain lighting up on seeing houses and other parts on seeing faces. The 'r' values are correlations, with higher positive or negative values indicating a better
72:, acquired using resting state fMRI, pre-processed to suppress the noise in data and played back at a real-time rate. The BOLD signal intensities are visualized on a smoothed cortical surface. At each point on the 110:
to evaluate regional interactions that occur in a resting or task-negative state, when an explicit task is not being performed. A number of resting-state brain networks have been identified, one of which is the
191:, or TR, which dictates how often a particular brain slice is excited and allowed to lose its magnetization. TRs could vary from the very short (500 ms) to the very long (3 seconds). For fMRI specifically, the 4615:"A systematic review of resting-state functional-MRI studies in anorexia nervosa: Evidence for functional connectivity impairment in cognitive control and visuospatial and body-signal integration" 4470:
Li P, Li S, Dong Z, Luo J, Han H, Xiong H, et al. (August 2012). "Altered resting state functional connectivity patterns of the anterior prefrontal cortex in obsessive-compulsive disorder".
453:. These metrics hold great potentials of accelerating biomarker identification for various brain diseases, which call the need of addressing reliability and reproducibility at first place. 444:
Resting-state functional magnetic resonance imaging (rfMRI) can image low-frequency fluctuations in the spontaneous brain activities, representing a popular tool for macro-scale functional
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Tessitore A, Amboni M, Esposito F, Russo A, Picillo M, Marcuccio L, et al. (July 2012). "Resting-state brain connectivity in patients with Parkinson's disease and freezing of gait".
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Anand A, Li Y, Wang Y, Wu J, Gao S, Bukhari L, et al. (May 2005). "Activity and connectivity of brain mood regulating circuit in depression: a functional magnetic resonance study".
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The physiological blood-flow response largely decides the temporal sensitivity, how well neurons that are active can be measured in BOLD fMRI. The basic time resolution parameter is the
160:(MRI) procedure that measures brain activity by detecting associated changes in blood flow. More specifically, brain activity is measured through low frequency BOLD signal in the brain. 355:
analysis techniques. Importantly, most of these resting-state components represent known functional networks, that is, regions that are known to share and support cognitive functions.
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functional brain networks. Mapping the brain's activity while it is at rest holds many potentials for brain research and even helps doctors diagnose various diseases of the brain.
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There are many methods of both acquiring and processing rsfMRI data. The most popular methods of analysis focus either on independent components or on regions of correlation.
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Zuo XN, Xing XX (September 2014). "Test-retest reliabilities of resting-state FMRI measurements in human brain functional connectomics: a systems neuroscience perspective".
3251:"Measuring and manipulating brain connectivity with resting state functional connectivity magnetic resonance imaging (fcMRI) and transcranial magnetic stimulation (TMS)" 3298:
Birn RM, Diamond JB, Smith MA, Bandettini PA (July 2006). "Separating respiratory-variation-related fluctuations from neuronal-activity-related fluctuations in fMRI".
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that result to be strongly functionally connected during rest. The key networks, also referred as components, which are more frequently reported include: the DMN, the
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FMRI is used both in research, and to a lesser extent, in clinical settings. It can also be combined and complemented with other measures of brain physiology such as
4343:, Kelly AM, Biswal BB, Margulies DS, Shehzad Z, Shaw D, et al. (March 2008). "Network homogeneity reveals decreased integrity of default-mode network in ADHD". 4910: 4232:"Lithium monotherapy associated clinical improvement effects on amygdala-ventromedial prefrontal cortex resting state connectivity in bipolar disorder" 207:
between spatially distinct brain regions reflects the repeated history of co-activation patterns within these regions, thereby serving as a measure of
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Kiviniemi V, Kantola JH, Jauhiainen J, HyvΓ€rinen A, Tervonen O (June 2003). "Independent component analysis of nondeterministic fMRI signal sources".
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Research using resting state fMRI has the potential to be applied in clinical context, including use in the assessment of many different diseases and
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Many imaging experts feel that in order to obtain the best combination of spatial and temporal information from brain activity, both fMRI as well as
76:, white color represents the average BOLD signal, while blue and red colors represents lower and higher signal than average BOLD signal respectively. 2518:"Atlas-based analysis of resting-state functional connectivity: evaluation for reproducibility and multi-modal anatomy-function correlation studies" 2967:
Long Z, Duan X, Wang Y, Liu F, Zeng L, Zhao JP, Chen H (January 2015). "Disrupted structural connectivity network in treatment-naive depression".
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533: 4773: 1715:"Effects on resting cerebral blood flow and functional connectivity induced by metoclopramide: a perfusion MRI study in healthy volunteers" 1619:
Biswal BB, Van Kylen J, Hyde JS (1997). "Simultaneous assessment of flow and BOLD signals in resting-state functional connectivity maps".
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This article is about resting state networks and functional imaging. For information regarding the Default Mode Network specifically, see
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external stimuli) brain responses and provided important new insights into baseline brain activity during resting wakefulness and sleep.
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3533:"Impact of in-scanner head motion on multiple measures of functional connectivity: relevance for studies of neurodevelopment in youth" 1304:"Synchronous multiscale neuroimaging environment for critically sampled physiological analysis of brain function: hepta-scan concept" 196:
smooth continuous function, sampling with faster TRs helps only to map faster fluctuations like respiratory and heart rate signals.
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Many programs exist for the processing and analyzing of resting state fMRI data. Some of the most commonly used programs include
17: 4566:"Functional network connectivity of pain-related resting state networks in somatoform pain disorder: an exploratory fMRI study" 381: 4824: 1442: 103: 4036:"Reciprocal effects of antidepressant treatment on activity and connectivity of the mood regulating circuit: an FMRI study" 2271:, Biswal BB, Castellanos FX, Milham MP (August 2007). "Mapping the functional connectivity of anterior cingulate cortex". 4962: 3390:
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started his work as a graduate student at The Medical College of Wisconsin under the direction of his advisor,
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of disorders, such as Schizophrenia, Depression, Stroke, and brain tumor, underpinning their unique symptoms.
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Depending on the method of resting state analysis, functional connectivity studies have reported a number of
896:"Effective Connectivity within the Default Mode Network: Dynamic Causal Modeling of Resting-State fMRI Data" 996:"Resting state fMRI: A review on methods in resting state connectivity analysis and resting state networks" 521: 120: 2316:"Intrinsic functional connectivity as a tool for human connectomics: theory, properties, and optimization" 4759: 4515:"Frequency shifts in the anterior default mode network and the salience network in chronic pain disorder" 2210:
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fMRI can be used as a complementary approach for assessing resting brain functions.
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Other methods of observing networks and connectivity in the brain include the
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Functional magnetic resonance imaging (functional MRI or fMRI) is a specific
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Evaluate regional interactions that occur in resting state(brain mapping)
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4782: 4723: 4581: 3741: 3435:"The influence of head motion on intrinsic functional connectivity MRI" 3174: 2227: 1953:"Consistency of network modules in resting-state FMRI connectome data" 962: 555:
Disease condition and changes in resting state functional connectivity
427:(ROI) methods of analysis. In these cases, signal from only a certain 4751: 4181:
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3580:
Saad ZS, Gotts SJ, Murphy K, Chen G, Jo HJ, Martin A, Cox RW (2012).
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and may also aid in understanding the development and progression of
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Li R, Wu X, Chen K, Fleisher AS, Reiman EM, Yao L (February 2013).
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Wu F, Tu Z, Sun J, Geng H, Zhou Y, Jiang X, et al. (2020).
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Fox MD, Halko MA, Eldaief MC, Pascual-Leone A (October 2012).
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Functional magnetic resonance imaging Β§ Issues in fMRI
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Anand A, Li Y, Wang Y, Lowe MJ, Dzemidzic M (March 2009).
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Greicius MD, Krasnow B, Reiss AL, Menon V (January 2003).
1516: 1174: 993: 4339: 4040:
The Journal of Neuropsychiatry and Clinical Neurosciences
3943: 2820:"Reducing the Cognitive Footprint of Brain Tumor Surgery" 2266: 2111: 1845: 944: 168: 4034:
Anand A, Li Y, Wang Y, Gardner K, Lowe MJ (2007-07-01).
3205: 2720:"Diffusion weighted imaging: Technique and applications" 2718:
Baliyan V, Das CJ, Sharma R, Gupta AK (September 2016).
2658: 1559: 115:. These brain networks are observed through changes in 2564: 2112:
Beckmann CF, DeLuca M, Devlin JT, Smith SM (May 2005).
2009: 1437:(2nd ed.). Sunderland, Mass.: Sinauer Associates. 1220:"Seven topics in functional magnetic resonance imaging" 3432: 3156: 2768: 1951:
Moussa MN, Steen MR, Laurienti PJ, Hayasaka S (2012).
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2717: 745: 607:(ADHD): altered "small networks" and thalamus changes 3807: 3433:
Van Dijk KR, Sabuncu MR, Buckner RL (January 2012).
2818:
Dadario NB, Brahimaj B, Yeung J, Sughrue ME (2021).
696:"Resting-state fMRI in the Human Connectome Project" 3579: 2515: 1618: 1432: 4033: 3850: 3671: 2362: 619:: disruption and decrease/increase in connectivity 542: 439: 4705:Lee, MH; Smyser, CD; Shimony, JS (October 2013). 4229: 3157:Majeed W, Magnuson M, Keilholz SD (August 2009). 1123: 850: 741: 739: 403: 4954: 4704: 3723: 4082: 3772: 3389: 3063: 2966: 613:: disruption of brain systems and motor network 456: 313: 142: 123:(BOLD) signal that can be measured using fMRI. 2868: 2160: 736: 595:: abnormal connectivity and network properties 4767: 3992: 3900: 2062: 1080: 27:Type of functional magnetic resonance imaging 4230:Altinay M, Karne H, Anand A (January 2018). 1295: 938: 4653: 4469: 3628: 3340: 3012: 2462: 4774: 4760: 4606: 3719: 3717: 3334: 3008: 3006: 1266: 1217: 987: 49: 4732: 4722: 4681: 4671: 4630: 4589: 4540: 4530: 4411: 4316: 4255: 4206: 4157: 4108: 4059: 4010: 3969: 3833: 3749: 3697: 3605: 3556: 3507: 3458: 3366: 3274: 3182: 3089: 3040: 3030: 2943: 2894: 2845: 2835: 2794: 2745: 2735: 2694: 2684: 2592: 2582: 2541: 2492: 2439: 2390: 2380: 2339: 2235: 2186: 2137: 2045: 2035: 1986: 1976: 1946: 1944: 1881: 1871: 1822: 1738: 1689: 1679: 1595: 1585: 1493: 1483: 1417: 1376: 1327: 1269:International Journal of Psychophysiology 1243: 1151: 1141: 1076: 1074: 1019: 970: 921: 911: 803: 801: 781: 771: 719: 4711:AJNR. American Journal of Neuroradiology 4570:Journal of Psychiatry & Neuroscience 4388:"Resting-state fMRI studies in epilepsy" 4385: 4279:Venkataraman A, Whitford TJ, Westin CF, 3730:AJNR. American Journal of Neuroradiology 3672:Holtbernd F, Eidelberg D (August 2012). 1433:Huettel SA, Song AW, McCarthy G (2008). 671:List of functional connectivity software 605:Attention deficit hyperactivity disorder 460: 436:distance, clustering, and graph theory. 291: 250:Washington University School of Medicine 146: 3714: 3003: 2615: 2161:Calhoun VD, de Lacy N (November 2017). 2154: 1904: 1804: 1661: 1399: 1124:Cole DM, Smith SM, Beckmann CF (2010). 301: 119:which creates what is referred to as a 14: 4955: 4781: 4619:Neuroscience and Biobehavioral Reviews 2618:Neuroscience and Biobehavioral Reviews 2012:"Clustering of resting state networks" 1941: 1510: 1071: 1042: 887: 844: 807: 798: 395: 182: 4755: 3766: 3163:Journal of Magnetic Resonance Imaging 2869:Konrad A, Winterer G (January 2008). 2167:Neuroimaging Clinics of North America 1761: 1435:Functional magnetic resonance imaging 527: 388:, and Connectome Computation System ( 104:functional magnetic resonance imaging 4437:Parkinsonism & Related Disorders 1117: 414: 3341:Chang C, Glover GH (October 2009). 1824:10.1146/annurev-neuro-071013-014030 1224:Journal of Integrative Neuroscience 631:: increase/decrease in connectivity 475:With fMRI providing functional and 24: 1807:"The brain's default mode network" 363: 25: 4984: 4875:Dorsal frontoparietal (Attention) 4660:Frontiers in Systems Neuroscience 4101:10.1016/j.pscychresns.2008.03.012 1130:Frontiers in Systems Neuroscience 518:Transcranial magnetic stimulation 358: 4870:Lateral frontoparietal (Control) 4449:10.1016/j.parkreldis.2012.03.018 4386:Zang YF, Zhao SG (August 2012). 3643:10.1016/j.neuroimage.2005.07.054 3549:10.1016/j.neuroimage.2011.12.063 3500:10.1016/j.neuroimage.2011.10.018 3451:10.1016/j.neuroimage.2011.07.044 3404:10.1016/j.neuroimage.2012.07.042 3359:10.1016/j.neuroimage.2009.04.048 3312:10.1016/j.neuroimage.2006.02.048 3267:10.1016/j.neuroimage.2012.03.035 2534:10.1016/j.neuroimage.2012.03.078 2485:10.1016/j.neuroimage.2009.12.011 2285:10.1016/j.neuroimage.2007.05.019 1919:10.1016/j.neuroimage.2011.10.035 1776:10.1016/j.neuroimage.2012.01.022 1731:10.1111/j.1476-5381.2010.01161.x 1369:10.1016/j.neuroimage.2008.01.006 1218:Bandettini PA (September 2009). 822:10.1016/j.neuroimage.2012.01.090 712:10.1016/j.neuroimage.2013.05.039 585:treatment: abnormal connectivity 512: 491: 470: 4937:Psychophysiological Interaction 4932:Dynamic functional connectivity 4860:Medial frontoparietal (Default) 4813:Data acquisition and processing 4698: 4647: 4632:10.1016/j.neubiorev.2016.09.032 4557: 4506: 4463: 4428: 4379: 4345:Journal of Neuroscience Methods 4333: 4272: 4223: 4174: 4125: 4076: 4027: 3986: 3937: 3894: 3801: 3665: 3622: 3573: 3524: 3475: 3426: 3383: 3291: 3242: 3199: 3150: 3106: 3057: 2960: 2911: 2862: 2811: 2762: 2711: 2652: 2630:10.1016/j.neubiorev.2014.05.009 2609: 2558: 2509: 2456: 2407: 2356: 2307: 2260: 2203: 2105: 2003: 1898: 1839: 1798: 1755: 1719:British Journal of Pharmacology 1706: 1655: 1612: 1553: 1451: 1426: 1393: 1344: 1260: 1211: 1177:Journal of Neuroscience Methods 1168: 900:Frontiers in Human Neuroscience 543:Current and future applications 440:Reliability and reproducibility 282:dynamic functional connectivity 260: 4357:10.1016/j.jneumeth.2007.11.031 4236:Journal of Affective Disorders 3962:10.1016/j.biopsych.2006.09.020 3915:10.1016/j.biopsych.2005.02.021 3775:Journal of Alzheimer's Disease 3208:Brain Structure & Function 2936:10.1016/j.biopsych.2010.03.035 2432:10.1523/JNEUROSCI.0536-12.2012 1281:10.1016/j.ijpsycho.2006.03.016 1057:10.1016/j.biopsych.2011.03.032 1036: 687: 409:Independent component analysis 404:Independent component analysis 277:post-traumatic stress disorder 13: 1: 4865:Midcingulo-insular (Salience) 2083:10.1016/S1053-8119(03)00097-1 1811:Annual Review of Neuroscience 681: 629:Obsessive compulsive disorder 334:(CEN), up to three different 265: 175:, and functional ultrasound. 4484:10.1097/wnr.0b013e328355a5fe 4301:10.1016/j.schres.2012.04.021 3690:10.1097/wco.0b013e328355aa94 3678:Current Opinion in Neurology 3128:10.1016/j.clinph.2006.05.018 3082:10.1161/STROKEAHA.110.596155 2037:10.1371/journal.pone.0040370 1978:10.1371/journal.pone.0044428 1681:10.1371/journal.pbio.1000033 1189:10.1016/0165-0270(94)90191-0 773:10.1371/journal.pone.0158504 522:Positron emission tomography 457:Combining imaging techniques 314:Other resting state networks 143:Basics of resting state fMRI 121:blood-oxygen-level dependent 7: 4654:Fox MD, Greicius M (2010). 4283:, Kubicki M (August 2012). 3872:10.1016/j.media.2016.08.003 2981:10.1016/j.pnpbp.2014.07.007 2420:The Journal of Neuroscience 1662:Friston K (February 2009). 654: 287: 244:Experiments by neurologist 10: 4989: 4963:Magnetic resonance imaging 2724:World Journal of Radiology 2320:Journal of Neurophysiology 1000:The Neuroradiology Journal 531: 214: 158:magnetic resonance imaging 29: 4919: 4893: 4880:Pericentral (Somatomotor) 4850: 4812: 4789: 4404:10.1007/s12264-012-1255-1 4248:10.1016/j.jad.2017.06.047 4052:10.1176/jnp.2007.19.3.274 3220:10.1007/s00429-010-0276-7 2837:10.3389/fneur.2021.711646 2571:Frontiers in Neuroscience 2179:10.1016/j.nic.2017.06.012 1236:10.1142/s0219635209002186 1095:10.1007/s10072-011-0636-y 567:Mild cognitive impairment 332:central executive network 81: 48: 43: 4794:Human Connectome Project 4673:10.3389/fnsys.2010.00019 3116:Clinical Neurophysiology 3032:10.3389/fpsyt.2019.00983 2584:10.3389/fnins.2017.00075 2267:Margulies DS, Kelly AM, 1805:Raichle ME (July 2015). 1531:10.1177/1073858414524442 1400:Bertolo, Adrien (2023). 1143:10.3389/fnsys.2010.00008 1012:10.1177/1971400917697342 913:10.3389/fnhum.2016.00014 563:: decreased connectivity 380:(esp. Melodic for ICA), 68:of a human subject from 4942:Dynamic causal modeling 4894:Functional modes/states 4820:Functional neuroimaging 4532:10.1186/1471-244x-13-84 4199:10.1089/brain.2015.0396 4138:Neuropsychopharmacology 3999:Neuropsychopharmacology 3787:10.3233/JAD-2012-111721 3598:10.1089/brain.2012.0080 3019:Frontiers in Psychiatry 2686:10.1073/pnas.0504136102 1873:10.1073/pnas.0135058100 1587:10.1073/pnas.0504136102 1485:10.1073/pnas.0601417103 1320:10.1089/brain.2014.0258 676:Medical image computing 569:: abnormal connectivity 346:attention network, the 205:functional connectivity 117:blood flow in the brain 106:(fMRI) that is used in 18:Functional connectivity 4289:Schizophrenia Research 4012:10.1038/sj.npp.1300725 3860:Medical Image Analysis 2875:Schizophrenia Bulletin 2824:Frontiers in Neurology 2775:Operative Neurosurgery 2130:10.1098/rstb.2005.1634 637:: altered connectivity 625:: altered connectivity 575:: altered connectivity 498:electroencephalography 467: 298: 177:Arterial spin labeling 153: 34:. For other uses, see 4392:Neuroscience Bulletin 3950:Biological Psychiatry 3903:Biological Psychiatry 3826:10.1093/cercor/bhq296 2924:Biological Psychiatry 2887:10.1093/schbul/sbm034 2737:10.4329/wjr.v8.i9.785 2332:10.1152/jn.00783.2009 1083:Neurological Sciences 1045:Biological Psychiatry 532:Further information: 464: 295: 193:haemodynamic response 150: 64:BOLD signal from the 36:Rest (disambiguation) 4150:10.1038/npp.2016.112 2382:10.7759/cureus.19105 1419:10.1162/imag_a_00030 1406:Imaging Neuroscience 601:: disrupted networks 434:dynamic time warping 421:seed-based d mapping 308:default mode network 302:Default mode network 255:Default Mode Network 113:default mode network 32:Default mode network 4920:Analytic strategies 4852:Functional networks 4089:Psychiatry Research 2677:2005PNAS..102.9673F 2216:Human Brain Mapping 2124:(1457): 1001–1013. 2077:(2 Pt 1): 253–260. 2028:2012PLoSO...740370L 1969:2012PLoSO...744428M 1864:2003PNAS..100..253G 1578:2005PNAS..102.9673F 1476:2006PNAS..10313848D 1470:(37): 13848–13853. 951:Human Brain Mapping 853:Nature Neuroscience 764:2016PLoSO..1158504B 623:Parkinson's disease 561:Alzheimer's disease 396:Methods of analysis 183:Physiological basis 4906:Resting state fMRI 4885:Occipital (Visual) 4837:Diffusion-weighted 4783:Human connectomics 4724:10.3174/ajnr.A3263 4582:10.1503/jpn.110187 4187:Brain Connectivity 3742:10.3174/ajnr.A3197 3586:Brain Connectivity 3175:10.1002/jmri.21848 2787:10.1093/ons/opy253 2781:(suppl_1): S1–S9. 1621:NMR in Biomedicine 1519:The Neuroscientist 1308:Brain Connectivity 528:Potential pitfalls 468: 425:region of interest 299: 154: 92:Resting state fMRI 44:Resting state fMRI 4950: 4949: 4911:Naturalistic fMRI 4144:(13): 3016–3024. 3909:(10): 1079–1088. 3820:(10): 2233–2243. 2671:(27): 9673–9678. 2426:(26): 8988–8999. 2228:10.1002/hbm.25728 1572:(27): 9673–9678. 1444:978-0-87893-286-3 963:10.1002/hbm.24539 415:Regional analysis 102:) is a method of 89: 88: 56: 16:(Redirected from 4980: 4776: 4769: 4762: 4753: 4752: 4747: 4746: 4736: 4726: 4702: 4696: 4695: 4685: 4675: 4651: 4645: 4644: 4634: 4610: 4604: 4603: 4593: 4561: 4555: 4554: 4544: 4534: 4510: 4504: 4503: 4467: 4461: 4460: 4432: 4426: 4425: 4415: 4383: 4377: 4376: 4337: 4331: 4330: 4320: 4276: 4270: 4269: 4259: 4227: 4221: 4220: 4210: 4178: 4172: 4171: 4161: 4129: 4123: 4122: 4112: 4080: 4074: 4073: 4063: 4031: 4025: 4024: 4014: 4005:(7): 1334–1344. 3990: 3984: 3983: 3973: 3941: 3935: 3934: 3898: 3892: 3891: 3854: 3848: 3847: 3837: 3805: 3799: 3798: 3770: 3764: 3763: 3753: 3721: 3712: 3711: 3701: 3669: 3663: 3662: 3626: 3620: 3619: 3609: 3577: 3571: 3570: 3560: 3528: 3522: 3521: 3511: 3494:(3): 2142–2154. 3479: 3473: 3472: 3462: 3430: 3424: 3423: 3398:(3): 1487–1497. 3387: 3381: 3380: 3370: 3338: 3332: 3331: 3306:(4): 1536–1548. 3295: 3289: 3288: 3278: 3261:(4): 2232–2243. 3246: 3240: 3239: 3203: 3197: 3196: 3186: 3154: 3148: 3147: 3122:(9): 2039–2049. 3110: 3104: 3103: 3093: 3076:(5): 1357–1362. 3061: 3055: 3054: 3044: 3034: 3010: 3001: 3000: 2964: 2958: 2957: 2947: 2915: 2909: 2908: 2898: 2866: 2860: 2859: 2849: 2839: 2815: 2809: 2808: 2798: 2766: 2760: 2759: 2749: 2739: 2715: 2709: 2708: 2698: 2688: 2656: 2650: 2649: 2613: 2607: 2606: 2596: 2586: 2562: 2556: 2555: 2545: 2513: 2507: 2506: 2496: 2460: 2454: 2453: 2443: 2411: 2405: 2404: 2394: 2384: 2360: 2354: 2353: 2343: 2311: 2305: 2304: 2264: 2258: 2257: 2239: 2222:(4): 1358–1369. 2207: 2201: 2200: 2190: 2158: 2152: 2151: 2141: 2109: 2103: 2102: 2066: 2060: 2059: 2049: 2039: 2007: 2001: 2000: 1990: 1980: 1948: 1939: 1938: 1913:(2): 1137–1145. 1902: 1896: 1895: 1885: 1875: 1843: 1837: 1836: 1826: 1802: 1796: 1795: 1770:(2): 1257–1266. 1759: 1753: 1752: 1742: 1725:(8): 1639–1652. 1710: 1704: 1703: 1693: 1683: 1659: 1653: 1652: 1627:(4–5): 165–170. 1616: 1610: 1609: 1599: 1589: 1557: 1551: 1550: 1514: 1508: 1507: 1497: 1487: 1455: 1449: 1448: 1430: 1424: 1423: 1421: 1397: 1391: 1390: 1380: 1363:(4): 1595–1605. 1348: 1342: 1341: 1331: 1299: 1293: 1292: 1264: 1258: 1257: 1247: 1215: 1209: 1208: 1172: 1166: 1165: 1155: 1145: 1121: 1115: 1114: 1078: 1069: 1068: 1040: 1034: 1033: 1023: 991: 985: 984: 974: 957:(8): 2488–2498. 942: 936: 935: 925: 915: 891: 885: 884: 848: 842: 841: 805: 796: 795: 785: 775: 743: 734: 733: 723: 691: 641:Anorexia nervosa 593:mood stabilizers 589:Bipolar disorder 549:mental disorders 350:network and the 273:bipolar disorder 137:mental disorders 66:cortical surface 58: 57: 41: 40: 21: 4988: 4987: 4983: 4982: 4981: 4979: 4978: 4977: 4968:Medical imaging 4953: 4952: 4951: 4946: 4927:Network science 4915: 4889: 4846: 4808: 4785: 4780: 4750: 4717:(10): 1866–72. 4703: 4699: 4652: 4648: 4611: 4607: 4562: 4558: 4511: 4507: 4478:(11): 681–686. 4468: 4464: 4433: 4429: 4384: 4380: 4338: 4334: 4277: 4273: 4228: 4224: 4179: 4175: 4130: 4126: 4081: 4077: 4032: 4028: 3991: 3987: 3942: 3938: 3899: 3895: 3855: 3851: 3814:Cerebral Cortex 3806: 3802: 3771: 3767: 3722: 3715: 3670: 3666: 3627: 3623: 3578: 3574: 3529: 3525: 3480: 3476: 3431: 3427: 3388: 3384: 3339: 3335: 3296: 3292: 3247: 3243: 3204: 3200: 3155: 3151: 3111: 3107: 3062: 3058: 3011: 3004: 2965: 2961: 2916: 2912: 2867: 2863: 2816: 2812: 2767: 2763: 2716: 2712: 2657: 2653: 2614: 2610: 2563: 2559: 2514: 2510: 2461: 2457: 2412: 2408: 2361: 2357: 2312: 2308: 2265: 2261: 2208: 2204: 2159: 2155: 2110: 2106: 2067: 2063: 2008: 2004: 1949: 1942: 1903: 1899: 1844: 1840: 1803: 1799: 1760: 1756: 1711: 1707: 1660: 1656: 1617: 1613: 1558: 1554: 1515: 1511: 1456: 1452: 1445: 1431: 1427: 1398: 1394: 1349: 1345: 1300: 1296: 1265: 1261: 1216: 1212: 1173: 1169: 1122: 1118: 1079: 1072: 1041: 1037: 992: 988: 943: 939: 892: 888: 865:10.1038/nn.3423 849: 845: 806: 799: 758:(7): e0158504. 744: 737: 692: 688: 684: 657: 591:and effects of 581:and effects of 557: 545: 536: 530: 515: 494: 473: 459: 442: 417: 406: 398: 366: 364:Processing data 361: 320:neural networks 316: 304: 297:gyrus; maroon). 290: 268: 263: 217: 185: 145: 77: 50: 39: 28: 23: 22: 15: 12: 11: 5: 4986: 4976: 4975: 4970: 4965: 4948: 4947: 4945: 4944: 4939: 4934: 4929: 4923: 4921: 4917: 4916: 4914: 4913: 4908: 4903: 4897: 4895: 4891: 4890: 4888: 4887: 4882: 4877: 4872: 4867: 4862: 4856: 4854: 4848: 4847: 4845: 4844: 4839: 4834: 4822: 4816: 4814: 4810: 4809: 4807: 4806: 4801: 4796: 4790: 4787: 4786: 4779: 4778: 4771: 4764: 4756: 4749: 4748: 4697: 4646: 4605: 4556: 4519:BMC Psychiatry 4505: 4462: 4443:(6): 781–787. 4427: 4398:(4): 449–455. 4378: 4351:(1): 249–254. 4332: 4271: 4222: 4193:(3): 255–265. 4173: 4124: 4095:(3): 189–198. 4075: 4046:(3): 274–282. 4026: 3985: 3956:(5): 429–437. 3936: 3893: 3849: 3800: 3781:(3): 475–487. 3765: 3713: 3684:(4): 392–401. 3664: 3637:(1): 145–154. 3621: 3572: 3543:(1): 623–632. 3523: 3474: 3445:(1): 431–438. 3425: 3382: 3353:(4): 1381–93. 3333: 3290: 3241: 3214:(2): 129–140. 3198: 3169:(2): 384–393. 3149: 3105: 3056: 3002: 2959: 2910: 2861: 2810: 2761: 2730:(9): 785–798. 2710: 2651: 2608: 2557: 2528:(3): 613–621. 2508: 2467:(March 2010). 2455: 2406: 2375:(10): e19105. 2355: 2326:(1): 297–321. 2306: 2279:(2): 579–588. 2259: 2202: 2173:(4): 561–579. 2153: 2104: 2061: 2002: 1940: 1897: 1858:(1): 253–258. 1838: 1817:(1): 433–447. 1797: 1754: 1705: 1654: 1611: 1552: 1525:(5): 522–533. 1509: 1450: 1443: 1425: 1392: 1343: 1314:(9): 677–689. 1294: 1275:(2): 138–145. 1259: 1230:(3): 371–403. 1210: 1183:(2): 171–187. 1167: 1116: 1089:(5): 773–785. 1070: 1035: 1006:(4): 305–317. 986: 937: 886: 859:(7): 832–837. 843: 816:(2): 938–944. 797: 735: 685: 683: 680: 679: 678: 673: 668: 663: 656: 653: 648: 647: 645:insular cortex 638: 632: 626: 620: 614: 608: 602: 596: 586: 583:antidepressant 576: 570: 564: 556: 553: 544: 541: 529: 526: 514: 511: 493: 490: 472: 469: 458: 455: 441: 438: 416: 413: 405: 402: 397: 394: 365: 362: 360: 359:Analyzing data 357: 330:networks, the 315: 312: 303: 300: 289: 286: 267: 264: 262: 259: 246:Marcus Raichle 240:Marcus Raichle 216: 213: 203:Resting state 184: 181: 144: 141: 128:brain activity 87: 86: 83: 79: 78: 59: 46: 45: 26: 9: 6: 4: 3: 2: 4985: 4974: 4971: 4969: 4966: 4964: 4961: 4960: 4958: 4943: 4940: 4938: 4935: 4933: 4930: 4928: 4925: 4924: 4922: 4918: 4912: 4909: 4907: 4904: 4902: 4899: 4898: 4896: 4892: 4886: 4883: 4881: 4878: 4876: 4873: 4871: 4868: 4866: 4863: 4861: 4858: 4857: 4855: 4853: 4849: 4843: 4840: 4838: 4835: 4832: 4831: 4826: 4825:BOLD-weighted 4823: 4821: 4818: 4817: 4815: 4811: 4805: 4802: 4800: 4799:Brain mapping 4797: 4795: 4792: 4791: 4788: 4784: 4777: 4772: 4770: 4765: 4763: 4758: 4757: 4754: 4744: 4740: 4735: 4730: 4725: 4720: 4716: 4712: 4708: 4701: 4693: 4689: 4684: 4679: 4674: 4669: 4665: 4661: 4657: 4650: 4642: 4638: 4633: 4628: 4624: 4620: 4616: 4609: 4601: 4597: 4592: 4587: 4583: 4579: 4575: 4571: 4567: 4560: 4552: 4548: 4543: 4538: 4533: 4528: 4524: 4520: 4516: 4509: 4501: 4497: 4493: 4489: 4485: 4481: 4477: 4473: 4466: 4458: 4454: 4450: 4446: 4442: 4438: 4431: 4423: 4419: 4414: 4409: 4405: 4401: 4397: 4393: 4389: 4382: 4374: 4370: 4366: 4362: 4358: 4354: 4350: 4346: 4342: 4336: 4328: 4324: 4319: 4314: 4310: 4309:1721.1/100215 4306: 4302: 4298: 4295:(1–3): 7–12. 4294: 4290: 4286: 4282: 4275: 4267: 4263: 4258: 4253: 4249: 4245: 4241: 4237: 4233: 4226: 4218: 4214: 4209: 4204: 4200: 4196: 4192: 4188: 4184: 4177: 4169: 4165: 4160: 4155: 4151: 4147: 4143: 4139: 4135: 4128: 4120: 4116: 4111: 4106: 4102: 4098: 4094: 4090: 4086: 4079: 4071: 4067: 4062: 4057: 4053: 4049: 4045: 4041: 4037: 4030: 4022: 4018: 4013: 4008: 4004: 4000: 3996: 3989: 3981: 3977: 3972: 3967: 3963: 3959: 3955: 3951: 3947: 3940: 3932: 3928: 3924: 3920: 3916: 3912: 3908: 3904: 3897: 3889: 3885: 3881: 3877: 3873: 3869: 3865: 3861: 3853: 3845: 3841: 3836: 3831: 3827: 3823: 3819: 3815: 3811: 3804: 3796: 3792: 3788: 3784: 3780: 3776: 3769: 3761: 3757: 3752: 3747: 3743: 3739: 3735: 3731: 3727: 3720: 3718: 3709: 3705: 3700: 3695: 3691: 3687: 3683: 3679: 3675: 3668: 3660: 3656: 3652: 3648: 3644: 3640: 3636: 3632: 3625: 3617: 3613: 3608: 3603: 3599: 3595: 3591: 3587: 3583: 3576: 3568: 3564: 3559: 3554: 3550: 3546: 3542: 3538: 3534: 3527: 3519: 3515: 3510: 3505: 3501: 3497: 3493: 3489: 3485: 3478: 3470: 3466: 3461: 3456: 3452: 3448: 3444: 3440: 3436: 3429: 3421: 3417: 3413: 3409: 3405: 3401: 3397: 3393: 3386: 3378: 3374: 3369: 3364: 3360: 3356: 3352: 3348: 3344: 3337: 3329: 3325: 3321: 3317: 3313: 3309: 3305: 3301: 3294: 3286: 3282: 3277: 3272: 3268: 3264: 3260: 3256: 3252: 3245: 3237: 3233: 3229: 3225: 3221: 3217: 3213: 3209: 3202: 3194: 3190: 3185: 3180: 3176: 3172: 3168: 3164: 3160: 3153: 3145: 3141: 3137: 3133: 3129: 3125: 3121: 3117: 3109: 3101: 3097: 3092: 3087: 3083: 3079: 3075: 3071: 3067: 3060: 3052: 3048: 3043: 3038: 3033: 3028: 3024: 3020: 3016: 3009: 3007: 2998: 2994: 2990: 2986: 2982: 2978: 2974: 2970: 2963: 2955: 2951: 2946: 2941: 2937: 2933: 2929: 2925: 2921: 2914: 2906: 2902: 2897: 2892: 2888: 2884: 2880: 2876: 2872: 2865: 2857: 2853: 2848: 2843: 2838: 2833: 2829: 2825: 2821: 2814: 2806: 2802: 2797: 2792: 2788: 2784: 2780: 2776: 2772: 2765: 2757: 2753: 2748: 2743: 2738: 2733: 2729: 2725: 2721: 2714: 2706: 2702: 2697: 2692: 2687: 2682: 2678: 2674: 2670: 2666: 2662: 2655: 2647: 2643: 2639: 2635: 2631: 2627: 2623: 2619: 2612: 2604: 2600: 2595: 2590: 2585: 2580: 2576: 2572: 2568: 2561: 2553: 2549: 2544: 2539: 2535: 2531: 2527: 2523: 2519: 2512: 2504: 2500: 2495: 2490: 2486: 2482: 2478: 2474: 2470: 2466: 2459: 2451: 2447: 2442: 2437: 2433: 2429: 2425: 2421: 2417: 2410: 2402: 2398: 2393: 2388: 2383: 2378: 2374: 2370: 2366: 2359: 2351: 2347: 2342: 2337: 2333: 2329: 2325: 2321: 2317: 2310: 2302: 2298: 2294: 2290: 2286: 2282: 2278: 2274: 2270: 2263: 2255: 2251: 2247: 2243: 2238: 2233: 2229: 2225: 2221: 2217: 2213: 2206: 2198: 2194: 2189: 2184: 2180: 2176: 2172: 2168: 2164: 2157: 2149: 2145: 2140: 2135: 2131: 2127: 2123: 2119: 2115: 2108: 2100: 2096: 2092: 2088: 2084: 2080: 2076: 2072: 2065: 2057: 2053: 2048: 2043: 2038: 2033: 2029: 2025: 2022:(7): e40370. 2021: 2017: 2013: 2006: 1998: 1994: 1989: 1984: 1979: 1974: 1970: 1966: 1963:(8): e44428. 1962: 1958: 1954: 1947: 1945: 1936: 1932: 1928: 1924: 1920: 1916: 1912: 1908: 1901: 1893: 1889: 1884: 1879: 1874: 1869: 1865: 1861: 1857: 1853: 1849: 1842: 1834: 1830: 1825: 1820: 1816: 1812: 1808: 1801: 1793: 1789: 1785: 1781: 1777: 1773: 1769: 1765: 1758: 1750: 1746: 1741: 1736: 1732: 1728: 1724: 1720: 1716: 1709: 1701: 1697: 1692: 1687: 1682: 1677: 1673: 1669: 1665: 1658: 1650: 1646: 1642: 1638: 1634: 1630: 1626: 1622: 1615: 1607: 1603: 1598: 1593: 1588: 1583: 1579: 1575: 1571: 1567: 1563: 1556: 1548: 1544: 1540: 1536: 1532: 1528: 1524: 1520: 1513: 1505: 1501: 1496: 1491: 1486: 1481: 1477: 1473: 1469: 1465: 1461: 1454: 1446: 1440: 1436: 1429: 1420: 1415: 1411: 1407: 1403: 1396: 1388: 1384: 1379: 1374: 1370: 1366: 1362: 1358: 1354: 1347: 1339: 1335: 1330: 1325: 1321: 1317: 1313: 1309: 1305: 1298: 1290: 1286: 1282: 1278: 1274: 1270: 1263: 1255: 1251: 1246: 1241: 1237: 1233: 1229: 1225: 1221: 1214: 1206: 1202: 1198: 1194: 1190: 1186: 1182: 1178: 1171: 1163: 1159: 1154: 1149: 1144: 1139: 1135: 1131: 1127: 1120: 1112: 1108: 1104: 1100: 1096: 1092: 1088: 1084: 1077: 1075: 1066: 1062: 1058: 1054: 1050: 1046: 1039: 1031: 1027: 1022: 1017: 1013: 1009: 1005: 1001: 997: 990: 982: 978: 973: 968: 964: 960: 956: 952: 948: 941: 933: 929: 924: 919: 914: 909: 905: 901: 897: 890: 882: 878: 874: 870: 866: 862: 858: 854: 847: 839: 835: 831: 827: 823: 819: 815: 811: 804: 802: 793: 789: 784: 779: 774: 769: 765: 761: 757: 753: 749: 742: 740: 731: 727: 722: 717: 713: 709: 705: 701: 697: 690: 686: 677: 674: 672: 669: 667: 664: 662: 659: 658: 652: 646: 642: 639: 636: 635:Pain disorder 633: 630: 627: 624: 621: 618: 615: 612: 609: 606: 603: 600: 599:Schizophrenia 597: 594: 590: 587: 584: 580: 577: 574: 571: 568: 565: 562: 559: 558: 552: 550: 540: 535: 525: 523: 519: 513:fMRI with TMS 510: 506: 503: 499: 492:fMRI with EEG 489: 485: 483: 478: 471:fMRI with DWI 463: 454: 452: 447: 437: 435: 430: 426: 422: 412: 410: 401: 393: 391: 387: 383: 379: 375: 371: 356: 353: 349: 345: 341: 337: 333: 329: 325: 321: 311: 309: 294: 285: 283: 278: 274: 258: 256: 251: 247: 242: 241: 237: 235: 231: 230:James S. Hyde 227: 226:Bharat Biswal 222: 221: 220:Bharat Biswal 212: 210: 206: 201: 197: 194: 190: 189:sampling rate 180: 178: 174: 170: 165: 161: 159: 149: 140: 138: 134: 129: 124: 122: 118: 114: 109: 108:brain mapping 105: 101: 97: 93: 84: 80: 75: 71: 67: 63: 60:Movie of the 47: 42: 37: 33: 19: 4973:Neuroimaging 4905: 4842:Tractography 4829: 4828: 4804:Neuroimaging 4714: 4710: 4700: 4663: 4659: 4649: 4622: 4618: 4608: 4576:(1): 57–65. 4573: 4569: 4559: 4522: 4518: 4508: 4475: 4471: 4465: 4440: 4436: 4430: 4395: 4391: 4381: 4348: 4344: 4335: 4292: 4288: 4274: 4239: 4235: 4225: 4190: 4186: 4176: 4141: 4137: 4127: 4092: 4088: 4078: 4043: 4039: 4029: 4002: 3998: 3988: 3953: 3949: 3939: 3906: 3902: 3896: 3863: 3859: 3852: 3817: 3813: 3803: 3778: 3774: 3768: 3736:(2): 340–5. 3733: 3729: 3681: 3677: 3667: 3634: 3630: 3624: 3592:(1): 25–32. 3589: 3585: 3575: 3540: 3536: 3526: 3491: 3487: 3477: 3442: 3438: 3428: 3395: 3391: 3385: 3350: 3346: 3336: 3303: 3299: 3293: 3258: 3254: 3244: 3211: 3207: 3201: 3166: 3162: 3152: 3119: 3115: 3108: 3073: 3069: 3059: 3022: 3018: 2972: 2968: 2962: 2930:(1): 61–69. 2927: 2923: 2913: 2881:(1): 72–92. 2878: 2874: 2864: 2827: 2823: 2813: 2778: 2774: 2764: 2727: 2723: 2713: 2668: 2664: 2654: 2621: 2617: 2611: 2574: 2570: 2560: 2525: 2521: 2511: 2479:(1): 81–98. 2476: 2472: 2458: 2423: 2419: 2409: 2372: 2368: 2358: 2323: 2319: 2309: 2276: 2272: 2262: 2219: 2215: 2205: 2170: 2166: 2156: 2121: 2117: 2107: 2074: 2070: 2064: 2019: 2015: 2005: 1960: 1956: 1910: 1906: 1900: 1855: 1851: 1841: 1814: 1810: 1800: 1767: 1763: 1757: 1722: 1718: 1708: 1671: 1668:PLOS Biology 1667: 1657: 1624: 1620: 1614: 1569: 1565: 1555: 1522: 1518: 1512: 1467: 1463: 1453: 1434: 1428: 1409: 1405: 1395: 1360: 1356: 1346: 1311: 1307: 1297: 1272: 1268: 1262: 1227: 1223: 1213: 1180: 1176: 1170: 1133: 1129: 1119: 1086: 1082: 1048: 1044: 1038: 1003: 999: 989: 954: 950: 940: 903: 899: 889: 856: 852: 846: 813: 809: 755: 751: 703: 699: 689: 666:Neuroimaging 661:Connectomics 649: 546: 537: 516: 507: 495: 486: 474: 451:connectomics 446:connectomics 443: 418: 407: 399: 367: 338:networks, a 317: 305: 269: 261:Connectivity 243: 239: 238: 223: 219: 218: 202: 198: 186: 166: 162: 155: 133:neurological 125: 99: 95: 91: 90: 4625:: 578–589. 4472:NeuroReport 3866:: 375–389. 2624:: 100–118. 1051:(9): 200S. 706:: 144–168. 611:Aging brain 4957:Categories 3631:NeuroImage 3537:NeuroImage 3488:NeuroImage 3439:NeuroImage 3392:NeuroImage 3347:NeuroImage 3300:NeuroImage 3255:NeuroImage 2830:: 711646. 2522:NeuroImage 2473:NeuroImage 2273:NeuroImage 2071:NeuroImage 1907:NeuroImage 1764:NeuroImage 1674:(2): e33. 1357:NeuroImage 810:NeuroImage 700:NeuroImage 682:References 579:Depression 466:displayed. 266:Functional 248:'s lab at 209:plasticity 4901:Task fMRI 4830:task-free 4281:Golland P 2975:: 18–26. 2465:Glover GH 2463:Chang C, 2254:244660926 1065:142478873 224:In 1992, 4743:22936095 4692:20592951 4641:27725172 4600:22894821 4551:23497482 4500:41049732 4492:22692554 4457:22510204 4422:22833042 4373:35668659 4365:18190970 4341:Uddin LQ 4327:22633528 4266:28772145 4242:: 4–12. 4217:26824737 4168:27356764 4119:19230623 4070:17827412 4021:15856081 3980:17210143 3931:19311022 3923:15866546 3880:27585835 3844:21378114 3795:22451310 3760:22790250 3708:22710361 3651:16202626 3616:22432927 3567:22233733 3518:22019881 3469:21810475 3412:22846657 3377:19393322 3320:16632379 3285:22465297 3236:25783833 3228:20853181 3193:19629982 3144:36779994 3136:16859985 3100:21441147 3051:32116814 2997:31447630 2989:25092218 2954:20497901 2905:17485733 2856:34484105 2805:30260422 2756:27721941 2705:15976020 2646:20844969 2638:24875392 2603:28261052 2552:22498656 2503:20006716 2450:22745498 2401:34858752 2350:19889849 2293:17604651 2269:Uddin LQ 2246:34826179 2197:28985929 2148:16087444 2099:17110486 2091:12814576 2056:22792291 2016:PLOS ONE 1997:22952978 1957:PLOS ONE 1927:22037421 1892:12506194 1833:25938726 1792:30701163 1784:22248579 1749:21175574 1700:19226186 1649:25428304 1606:15976020 1547:13300284 1539:24561514 1504:16945915 1412:: 1–18. 1387:18314354 1338:25131996 1289:16842871 1254:19938211 1162:20407579 1103:21667095 1030:28353416 981:30720907 932:26869900 881:17141252 873:23799476 830:22326802 792:27391481 752:PLOS ONE 730:23702415 655:See also 617:Epilepsy 502:EEG-fMRI 348:auditory 288:Networks 126:Because 4734:4035703 4683:2893721 4591:3529220 4542:3616999 4413:5561896 4318:3393792 4257:5844774 4208:4827275 4159:5101549 4110:3001251 4061:3465666 3971:2001244 3888:4922560 3835:3169656 3751:4097966 3699:4554600 3659:9228087 3607:3484684 3558:3746318 3509:3254728 3460:3683830 3368:2721281 3328:3892813 3276:3518426 3184:2758521 3091:3589816 3042:7013238 3025:: 983. 2945:2900394 2896:2632386 2847:8415405 2796:6887907 2747:5039674 2696:1157105 2673:Bibcode 2594:5313507 2543:3358461 2494:2827259 2441:3392686 2392:8614179 2341:2807224 2301:3330669 2237:8837585 2188:5657522 2139:1854918 2047:3392237 2024:Bibcode 1988:3432126 1965:Bibcode 1935:9880586 1860:Bibcode 1740:3166692 1691:2642881 1641:9430343 1597:1157105 1574:Bibcode 1495:1564249 1472:Bibcode 1378:2435272 1329:4238249 1245:3143579 1205:3718293 1197:7869750 1153:2854531 1021:5524274 972:6865559 923:4740785 783:4938391 760:Bibcode 721:3720828 340:ventral 324:sensory 234:mapping 215:History 96:rs-fMRI 82:Purpose 62:in vivo 4741:  4731:  4690:  4680:  4666:: 19. 4639:  4598:  4588:  4549:  4539:  4525:: 84. 4498:  4490:  4455:  4420:  4410:  4371:  4363:  4325:  4315:  4264:  4254:  4215:  4205:  4166:  4156:  4117:  4107:  4068:  4058:  4019:  3978:  3968:  3929:  3921:  3886:  3878:  3842:  3832:  3793:  3758:  3748:  3706:  3696:  3657:  3649:  3614:  3604:  3565:  3555:  3516:  3506:  3467:  3457:  3420:670206 3418:  3410:  3375:  3365:  3326:  3318:  3283:  3273:  3234:  3226:  3191:  3181:  3142:  3134:  3098:  3088:  3070:Stroke 3049:  3039:  2995:  2987:  2952:  2942:  2903:  2893:  2854:  2844:  2803:  2793:  2754:  2744:  2703:  2693:  2644:  2636:  2601:  2591:  2577:: 75. 2550:  2540:  2501:  2491:  2448:  2438:  2399:  2389:  2369:Cureus 2348:  2338:  2299:  2291:  2252:  2244:  2234:  2195:  2185:  2146:  2136:  2097:  2089:  2054:  2044:  1995:  1985:  1933:  1925:  1890:  1883:140943 1880:  1831:  1790:  1782:  1747:  1737:  1698:  1688:  1647:  1639:  1604:  1594:  1545:  1537:  1502:  1492:  1441:  1385:  1375:  1336:  1326:  1287:  1252:  1242:  1203:  1195:  1160:  1150:  1109:  1101:  1063:  1028:  1018:  979:  969:  930:  920:  906:: 14. 879:  871:  836:  828:  790:  780:  728:  718:  573:Autism 352:limbic 344:dorsal 336:visual 152:match. 100:R-fMRI 74:cortex 4496:S2CID 4369:S2CID 3927:S2CID 3884:S2CID 3655:S2CID 3416:S2CID 3324:S2CID 3232:S2CID 3140:S2CID 2993:S2CID 2642:S2CID 2297:S2CID 2250:S2CID 2095:S2CID 1931:S2CID 1788:S2CID 1645:S2CID 1543:S2CID 1201:S2CID 1136:: 8. 1111:17222 1107:S2CID 1061:S2CID 877:S2CID 838:93823 834:S2CID 429:voxel 386:C-PAC 328:motor 4739:PMID 4688:PMID 4637:PMID 4596:PMID 4547:PMID 4488:PMID 4453:PMID 4418:PMID 4361:PMID 4323:PMID 4262:PMID 4213:PMID 4164:PMID 4115:PMID 4066:PMID 4017:PMID 3976:PMID 3919:PMID 3876:PMID 3840:PMID 3791:PMID 3756:PMID 3704:PMID 3647:PMID 3612:PMID 3563:PMID 3514:PMID 3465:PMID 3408:PMID 3373:PMID 3316:PMID 3281:PMID 3224:PMID 3189:PMID 3132:PMID 3096:PMID 3047:PMID 2985:PMID 2950:PMID 2901:PMID 2852:PMID 2801:PMID 2752:PMID 2701:PMID 2634:PMID 2599:PMID 2548:PMID 2499:PMID 2446:PMID 2397:PMID 2346:PMID 2289:PMID 2242:PMID 2193:PMID 2144:PMID 2087:PMID 2052:PMID 1993:PMID 1923:PMID 1888:PMID 1829:PMID 1780:PMID 1745:PMID 1696:PMID 1637:PMID 1602:PMID 1535:PMID 1500:PMID 1439:ISBN 1383:PMID 1334:PMID 1285:PMID 1250:PMID 1193:PMID 1158:PMID 1099:PMID 1026:PMID 977:PMID 928:PMID 869:PMID 826:PMID 788:PMID 726:PMID 423:and 382:CONN 374:AFNI 342:and 306:The 173:NIRS 4729:PMC 4719:doi 4678:PMC 4668:doi 4627:doi 4586:PMC 4578:doi 4537:PMC 4527:doi 4480:doi 4445:doi 4408:PMC 4400:doi 4353:doi 4349:169 4313:PMC 4305:hdl 4297:doi 4293:139 4252:PMC 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Index

Functional connectivity
Default mode network
Rest (disambiguation)
in vivo
cortical surface
HCP
cortex
functional magnetic resonance imaging
brain mapping
default mode network
blood flow in the brain
blood-oxygen-level dependent
brain activity
neurological
mental disorders
fMRI images from a study showing parts of the brain lighting up on seeing houses and other parts on seeing faces
magnetic resonance imaging
EEG
NIRS
Arterial spin labeling
sampling rate
haemodynamic response
functional connectivity
plasticity
Bharat Biswal
James S. Hyde
mapping
Marcus Raichle
Washington University School of Medicine
Default Mode Network

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