Knowledge

ZAK

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Liu, Te-Chung; Huang, Chang-Jen; Chu, Yu-Chuan; Wei, Chih-Chang; Chou, Chun-Chieh; Chou, Ming-Yung; Chou, Chen-Kung; Yang, Jaw-Ji (11 August 2000). "Cloning and Expression of ZAK, a Mixed Lineage Kinase-like Protein Containing a Leucine-Zipper and a Sterile-Alpha Motif".
310: 209: 1977:"Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNA" 103:, AZK, MLK7, MLT, MLTK, MRK, mlklak, pk, ZAK, SFMMP, sterile alpha motif and leucine zipper containing kinase AZK, mitogen-activated protein kinase kinase kinase 20, MLTKalpha, MLTKbeta, CNM6 2155: 2440: 1839:
Huang CY, Kuo WW, Chueh PJ, et al. (2004). "Transforming growth factor-beta induces the expression of ANF and hypertrophic growth in cultured cardiomyoblast cells through ZAK".
1423:
Liu TC, Huang CJ, Chu YC, et al. (2000). "Cloning and expression of ZAK, a mixed lineage kinase-like protein containing a leucine-zipper and a sterile-alpha motif".
1868:
Huang CY, Chueh PJ, Tseng CT, et al. (2004). "ZAK re-programs atrial natriuretic factor expression and induces hypertrophic growth in H9c2 cardiomyoblast cells".
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and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in
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Yang JJ (2002). "Mixed lineage kinase ZAK utilizing MKK7 and not MKK4 to activate the c-Jun N-terminal kinase and playing a role in the cell arrest".
1344:
Yang, Jaw-Ji (Jan 2003). "A novel zinc finger protein, ZZaPK, interacts with ZAK and stimulates the ZAK-expressing cells re-entering the cell cycle".
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Bloem LJ, Pickard TR, Acton S, et al. (2002). "Tissue distribution and functional expression of a cDNA encoding a novel mixed lineage kinase".
1763:"Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization" 1728:"A novel role for mixed-lineage kinase-like mitogen-activated protein triple kinase alpha in neoplastic cell transformation and tumor development" 3693: 1633:
Yang JJ (2003). "A novel zinc finger protein, ZZaPK, interacts with ZAK and stimulates the ZAK-expressing cells re-entering the cell cycle".
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Takahashi M, Gotoh Y, Isagawa T, et al. (2004). "Regulation of a mitogen-activated protein kinase kinase kinase, MLTK by PKN".
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Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network".
1294: 3932: 3813: 4386: 3519: 2388: 4357: 3583: 2558: 1942:"Phosphorylation of Ser28 in histone H3 mediated by mixed lineage kinase-like mitogen-activated protein triple kinase alpha" 1238: 4376: 3839: 47: 2373: 1217: 3571: 3896: 4011: 2828: 2818: 2503: 2133: 296: 3510: 1806:"The stress kinase MRK contributes to regulation of DNA damage checkpoints through a p38gamma-independent pathway" 3779: 3451: 2813: 2804: 1242: 1221: 273: 896: 4167: 3194: 2691: 2682: 2339: 2285: 1899:"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" 1518:"MRK, a mixed lineage kinase-related molecule that plays a role in gamma-radiation-induced cell cycle arrest" 1386:
Lee, Jin-Sun (28 February 2018). "Antitumorigenic Effects of ZAKβ, an Alternative Splicing Isoform of ZAK".
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activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
195: 170: 112: 309: 208: 1189: 302: 201: 4282: 3406: 3224: 2720: 4350: 4268: 4255: 4242: 4229: 4216: 4203: 4190: 4152: 3396: 3391: 3386: 3376: 3371: 3366: 3356: 3151: 2926: 2522: 99: 4162: 4116: 4059: 3619: 3610: 3561: 2327: 2172: 1050: 991: 120: 4064: 3919: 3342: 1582:"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" 1058: 1054: 1029: 1025: 999: 995: 970: 966: 4085: 4004: 2618: 1173: 140: 4343: 4157: 3185: 2097: 2058: 1593: 184: 8: 4121: 3294: 2012:"Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer" 1165: 1153: 2185: 2101: 2062: 1597: 4381: 4054: 3796: 3750: 2121: 1792: 144: 1923: 1898: 1646: 1616: 1581: 1564: 1357: 766: 761: 756: 751: 746: 741: 736: 731: 726: 721: 716: 711: 706: 701: 696: 691: 686: 681: 665: 660: 655: 639: 634: 629: 624: 619: 614: 609: 604: 599: 594: 589: 3056: 2765: 2163: 2113: 2076: 2033: 1998: 1963: 1928: 1885: 1856: 1827: 1784: 1749: 1714: 1679: 1650: 1621: 1568: 1539: 1504: 1475: 1440: 1403: 1369: 1361: 1326: 92: 40: 124: 4100: 4095: 4069: 3997: 2794: 2785: 2715: 2706: 2652: 2643: 2300: 2125: 2105: 2066: 2023: 1988: 1953: 1918: 1910: 1877: 1848: 1817: 1796: 1774: 1739: 1704: 1671: 1642: 1611: 1601: 1560: 1529: 1496: 1465: 1432: 1395: 1353: 1318: 389: 320: 264: 219: 1744: 1727: 4147: 4131: 4044: 3475: 2546: 2541: 2536: 364: 148: 1278:
National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
4327: 4296: 4185: 4126: 2028: 2011: 1881: 1852: 1454:"Identification and characterization of a novel MAP kinase kinase kinase, MLTK" 1295:"Entrez Gene: ZAK sterile alpha motif and leucine zipper containing kinase AZK" 1161: 465: 1779: 1762: 4370: 4331: 4090: 4049: 2531: 2047:"Generation and annotation of the DNA sequences of human chromosomes 2 and 4" 1365: 1177: 576: 2599: 1693:"Complete sequencing and characterization of 21,243 full-length human cDNAs" 1399: 525: 403: 4323: 4039: 3470: 2295: 2117: 2080: 2037: 2002: 1993: 1976: 1967: 1958: 1941: 1932: 1889: 1860: 1831: 1822: 1805: 1788: 1753: 1718: 1683: 1654: 1625: 1606: 1572: 1543: 1534: 1517: 1508: 1500: 1479: 1470: 1453: 1444: 1436: 1407: 1373: 1330: 1322: 382: 161: 1122: 1117: 547: 4263: 4198: 4034: 3676: 3308: 3248: 3131: 3051: 2775: 941: 922: 2109: 2071: 2046: 1675: 3764: 2238: 1914: 1157: 281: 178: 128: 69: 4237: 4211: 2725: 1169: 796: 348: 335: 247: 234: 136: 4291: 3081: 2976: 2971: 2966: 1709: 1692: 1106: 2441:
3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) kinase
3740: 3718: 3713: 3703: 3698: 3500: 3495: 3490: 3485: 3480: 3465: 3460: 3111: 3076: 2315: 2310: 2305: 908: 863: 781: 777: 556: 116: 4250: 4020: 3970: 3965: 3960: 3955: 3950: 3945: 3940: 3891: 3886: 3881: 3876: 3871: 3854: 3849: 3723: 3708: 3659: 3654: 3639: 3634: 3629: 3624: 3598: 3593: 3588: 3576: 3554: 3549: 3441: 3416: 3091: 2916: 2911: 2906: 2901: 2886: 2730: 2667: 2662: 2657: 2633: 2459: 2454: 2428: 2423: 2418: 2408: 2403: 2393: 2233: 2164: 1193: 1149: 1090: 818: 4224: 3866: 3859: 3769: 3666: 3566: 3544: 3539: 3534: 3529: 3524: 3436: 3431: 3426: 3421: 3411: 3381: 3361: 3238: 3233: 3214: 3209: 3199: 3175: 3170: 3165: 3141: 3136: 3126: 3121: 3116: 3106: 3086: 3071: 3066: 3061: 3041: 3036: 3026: 3021: 3016: 3011: 3006: 2996: 2991: 2986: 2981: 2961: 2956: 2951: 2946: 2941: 2936: 2921: 2871: 2866: 2760: 2755: 2750: 2745: 2740: 2735: 2696: 2628: 2623: 2572: 2567: 2493: 2488: 2483: 2449: 2243: 2228: 2223: 2218: 2213: 2208: 1135:
Sterile alpha motif and leucine zipper containing kinase AZK
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Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
1142: 3989: 2263: 2248: 3918: 1579: 372: 1897:
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
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Hillier LW, Graves TA, Fulton RS, et al. (2005).
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Gross EA, Callow MG, Waldbaum L, et al. (2002).
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Benzinger A, Muster N, Koch HB, et al. (2005).
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Tosti E, Waldbaum L, Warshaw G, et al. (2005).
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Biochemical and Biophysical Research Communications
1691:Ota T, Suzuki Y, Nishikawa T, et al. (2004). 1690: 1451: 1234: 1232: 1230: 1213: 1211: 1209: 2087: 1486: 319: 218: 4368: 1975:Wang X, Mader MM, Toth JE, et al. (2005). 1867: 1726:Cho YY, Bode AM, Mizuno H, et al. (2004). 1227: 1206: 16:Protein-coding gene in the species Homo sapiens 1940:Choi HS, Choi BY, Cho YY, et al. (2005). 1761:Jin J, Smith FD, Stark C, et al. (2004). 1307: 1239:GRCm38: Ensembl release 89: ENSMUSG00000004085 4351: 4005: 2200:Non-specific serine/threonine protein kinases 2149: 1974: 1838: 1760: 1725: 1168:(SAM). This magnesium-binding protein forms 1939: 1422: 1337: 1218:GRCh38: Ensembl release 89: ENSG00000091436 4358: 4344: 4012: 3998: 2583:Goodpasture-antigen-binding protein kinase 2156: 2142: 1176:regulation in cells. The protein also has 418:Skeletal muscle tissue of rectus abdominis 3296:Serine/threonine-specific protein kinases 2470:(isocitrate dehydrogenase (NADP+)) kinase 2187:Serine/threonine-specific protein kinases 2169:Serine/threonine-specific protein kinases 2070: 2027: 1992: 1957: 1922: 1821: 1778: 1743: 1708: 1615: 1605: 1533: 1469: 3831:Receptor protein serine/threonine kinase 1289: 1287: 1156:molecules and encodes a protein with an 727:positive regulation of apoptotic process 615:protein serine/threonine kinase activity 426:Skeletal muscle tissue of biceps brachii 3814:Low-density-lipoprotein receptor kinase 1632: 1550: 1160:kinase catalytic domain, followed by a 757:mitotic cell cycle checkpoint signaling 4369: 3993: 3917: 3293: 2559:Fas-activated serine/threonine kinase 2184: 2137: 1452:Gotoh I, Adachi M, Nishida E (2001). 1284: 324: 285: 280: 223: 182: 177: 4306: 3931: 3840:Bone morphogenetic protein receptors 1343: 767:cellular response to gamma radiation 2374:Dephospho-(reductase kinase) kinase 1385: 13: 2829:G-protein coupled receptor kinases 1415: 14: 4398: 2819:Beta adrenergic receptor kinase-2 2504:(tyrosine 3-monooxygenase) kinase 1388:The Chinese Journal of Physiology 687:intracellular signal transduction 625:MAP kinase kinase kinase activity 4310: 4290: 3511:Mitogen-activated protein kinase 546: 308: 301: 295: 272: 207: 200: 194: 169: 3897:Anti-Müllerian hormone receptor 3780:(acetyl-CoA carboxylase) kinase 3452:(RNA-polymerase)-subunit kinase 2814:Beta adrenergic receptor kinase 2805:Beta adrenergic receptor kinase 1183: 702:DNA damage checkpoint signaling 692:cell cycle checkpoint signaling 3520:Extracellular signal-regulated 1301: 1266: 1248: 557:More reference expression data 526:More reference expression data 1: 4387:Human chromosome 2 gene stubs 3584:P38 mitogen-activated protein 2683:cGMP-dependent protein kinase 2644:cAMP-dependent protein kinase 2340:Pyruvate dehydrogenase kinase 2286:Ataxia telangiectasia mutated 1870:Biochem. Biophys. Res. Commun 1841:Biochem. Biophys. Res. Commun 1745:10.1158/0008-5472.CAN-04-0201 1647:10.1016/S0006-291X(02)02980-7 1635:Biochem. Biophys. Res. Commun 1565:10.1016/S0006-291X(02)02123-X 1553:Biochem. Biophys. Res. Commun 1425:Biochem. Biophys. Res. Commun 1358:10.1016/S0006-291X(02)02980-7 1346:Biochem. Biophys. Res. Commun 1199: 1148:This gene is a member of the 762:stress-activated MAPK cascade 747:embryonic digit morphogenesis 742:cell population proliferation 293: 192: 4330:. You can help Knowledge by 2383:AMP-activated protein kinase 1586:Proc. Natl. Acad. Sci. U.S.A 7: 4377:Genes on human chromosome 2 4019: 3298:(EC 2.7.11.21-EC 2.7.11.30) 10: 4403: 4305: 3225:Elongation factor 2 kinase 2189:(EC 2.7.11.1-EC 2.7.11.20) 2029:10.1074/mcp.M500021-MCP200 1882:10.1016/j.bbrc.2004.09.156 1853:10.1016/j.bbrc.2004.09.067 500:sternocleidomastoid muscle 4176: 4168:Michaelis–Menten kinetics 4140: 4109: 4078: 4027: 3927: 3913: 3829: 3812: 3795: 3778: 3749: 3620:MAP kinase kinase kinases 3609: 3509: 3450: 3341: 3307: 3303: 3289: 3247: 3223: 3184: 3152:Myosin light-chain kinase 3150: 2858:Ca2+/calmodulin-dependent 2856: 2827: 2803: 2784: 2705: 2681: 2642: 2598: 2581: 2557: 2523:Myosin-heavy-chain kinase 2521: 2502: 2468: 2439: 2372: 2338: 2198: 2194: 2180: 1780:10.1016/j.cub.2004.07.051 1274:"Mouse PubMed Reference:" 1256:"Human PubMed Reference:" 1121: 1116: 1112: 1105: 1089: 1076:Chr 2: 173.08 – 173.27 Mb 1070: 1047: 1043: 1022: 1018: 1011: 988: 984: 963: 959: 952: 939: 935: 920: 916: 907: 894: 890: 875: 871: 862: 849: 845: 830: 826: 817: 802: 795: 791: 775: 722:cytoskeleton organization 575: 571: 554: 545: 536: 523: 472: 463: 410: 401: 371: 363: 359: 342: 329: 292: 271: 262: 258: 241: 228: 191: 168: 159: 155: 110: 107: 97: 90: 85: 66: 61: 44: 39: 34: 30: 26: 21: 4060:Diffusion-limited enzyme 3920:Dual-specificity kinases 3343:Cyclin-dependent kinase 1400:10.4077/CJP.2018.BAG528 1083:Chr 2: 72.12 – 72.27 Mb 717:protein phosphorylation 600:protein kinase activity 476:interventricular septum 1994:10.1074/jbc.M413059200 1959:10.1074/jbc.M410521200 1823:10.1074/jbc.M409961200 1607:10.1073/pnas.242603899 1535:10.1074/jbc.M111994200 1501:10.1006/jmcc.2001.1437 1471:10.1074/jbc.M008595200 1437:10.1006/bbrc.2000.3236 1323:10.1006/bbrc.2000.3236 1188:ZAK has been shown to 508:atrioventricular valve 488:triceps brachii muscle 4153:Eadie–Hofstee diagram 4086:Allosteric regulation 2016:Mol. Cell. Proteomics 1489:J. Mol. Cell. Cardiol 1174:cell cycle checkpoint 737:response to radiation 635:magnesium ion binding 4163:Lineweaver–Burk plot 3186:Phosphorylase kinase 682:cell differentiation 590:transferase activity 287:Chromosome 2 (mouse) 185:Chromosome 2 (human) 62:List of PDB id codes 35:Available structures 2110:10.1038/nature04209 2102:2005Natur.437.1173R 2072:10.1038/nature03466 2063:2005Natur.434..724H 1598:2002PNAS...9916899M 1166:sterile-alpha motif 1154:signal transduction 149:MAP3K20 - orthologs 4318:This article on a 4122:Enzyme superfamily 4055:Enzyme promiscuity 3797:Tropomyosin kinase 3751:Tau-protein kinase 1915:10.1101/gr.2596504 897:ENSMUSG00000004085 707:response to stress 675:Biological process 649:Cellular component 595:nucleotide binding 583:Molecular function 512:intercostal muscle 496:extraocular muscle 438:tail of epididymis 4339: 4338: 4278: 4277: 3987: 3986: 3983: 3982: 3979: 3978: 3909: 3908: 3905: 3904: 3285: 3284: 3281: 3280: 2766:Protein kinase N1 2721:Protein kinase Cζ 1987:(19): 19298–305. 1676:10.1093/jb/mvg022 1592:(26): 16899–903. 1132: 1131: 1128: 1127: 1101: 1100: 1066: 1065: 1037: 1036: 1007: 1006: 978: 977: 948: 947: 929: 928: 903: 902: 884: 883: 858: 857: 839: 838: 787: 786: 605:metal ion binding 567: 566: 563: 562: 532: 531: 519: 518: 457: 456: 355: 354: 254: 253: 81: 80: 77: 76: 45:Ortholog search: 4394: 4360: 4353: 4346: 4314: 4307: 4295: 4294: 4286: 4158:Hanes–Woolf plot 4101:Enzyme activator 4096:Enzyme inhibitor 4070:Enzyme catalysis 4014: 4007: 4000: 3991: 3990: 3929: 3928: 3915: 3914: 3562:C-Jun N-terminal 3305: 3304: 3291: 3290: 2795:Rhodopsin kinase 2786:Rhodopsin kinase 2716:Protein kinase C 2707:Protein kinase C 2692:Protein kinase G 2653:Protein kinase A 2264:Protein kinase B 2196: 2195: 2182: 2181: 2158: 2151: 2144: 2135: 2134: 2129: 2096:(7062): 1173–8. 2084: 2074: 2057:(7034): 724–31. 2041: 2031: 2006: 1996: 1971: 1961: 1952:(14): 13545–53. 1936: 1926: 1893: 1864: 1835: 1825: 1816:(46): 47652–60. 1800: 1782: 1757: 1747: 1722: 1712: 1687: 1658: 1629: 1619: 1609: 1576: 1547: 1537: 1528:(16): 13873–82. 1512: 1483: 1473: 1448: 1411: 1378: 1377: 1341: 1335: 1334: 1305: 1299: 1298: 1291: 1282: 1281: 1270: 1264: 1263: 1252: 1246: 1236: 1225: 1215: 1137:, also known as 1114: 1113: 1085: 1078: 1061: 1041: 1040: 1032: 1016: 1015: 1012:RefSeq (protein) 1002: 982: 981: 973: 957: 956: 933: 932: 914: 913: 888: 887: 869: 868: 843: 842: 824: 823: 793: 792: 752:limb development 573: 572: 559: 550: 543: 542: 528: 492:digastric muscle 468: 466:Top expressed in 461: 460: 450:seminal vesicula 406: 404:Top expressed in 399: 398: 378: 377: 361: 360: 351: 338: 327: 312: 305: 299: 288: 276: 260: 259: 250: 237: 226: 211: 204: 198: 187: 173: 157: 156: 151: 102: 95: 72: 59: 58: 53: 32: 31: 19: 18: 4402: 4401: 4397: 4396: 4395: 4393: 4392: 4391: 4367: 4366: 4365: 4364: 4303: 4301: 4289: 4281: 4279: 4274: 4186:Oxidoreductases 4172: 4148:Enzyme kinetics 4136: 4132:List of enzymes 4105: 4074: 4045:Catalytic triad 4023: 4018: 3988: 3975: 3923: 3901: 3825: 3808: 3791: 3774: 3745: 3605: 3505: 3476:P70-S6 Kinase 1 3446: 3337: 3299: 3277: 3243: 3219: 3180: 3146: 2852: 2823: 2799: 2780: 2701: 2677: 2638: 2594: 2577: 2553: 2547:Aurora C kinase 2542:Aurora B kinase 2537:Aurora A kinase 2517: 2498: 2464: 2435: 2368: 2334: 2190: 2176: 2162: 2132: 1909:(10B): 2121–7. 1773:(16): 1436–50. 1738:(11): 3855–64. 1418: 1416:Further reading 1382: 1381: 1342: 1338: 1306: 1302: 1293: 1292: 1285: 1272: 1271: 1267: 1254: 1253: 1249: 1237: 1228: 1216: 1207: 1202: 1186: 1123:View/Edit Mouse 1118:View/Edit Human 1081: 1074: 1071:Location (UCSC) 1057: 1053: 1049: 1028: 1024: 998: 994: 990: 969: 965: 878:ENSG00000091436 771: 697:phosphorylation 670: 644: 620:protein binding 610:kinase activity 555: 524: 515: 510: 506: 502: 498: 494: 490: 486: 482: 480:temporal muscle 478: 464: 453: 448: 444: 440: 436: 432: 428: 424: 420: 416: 414:right ventricle 402: 346: 333: 325: 315: 314: 313: 306: 286: 263:Gene location ( 245: 232: 224: 214: 213: 212: 205: 183: 160:Gene location ( 111: 98: 91: 68: 46: 17: 12: 11: 5: 4400: 4390: 4389: 4384: 4379: 4363: 4362: 4355: 4348: 4340: 4337: 4336: 4315: 4300: 4299: 4276: 4275: 4273: 4272: 4259: 4246: 4233: 4220: 4207: 4194: 4180: 4178: 4174: 4173: 4171: 4170: 4165: 4160: 4155: 4150: 4144: 4142: 4138: 4137: 4135: 4134: 4129: 4124: 4119: 4113: 4111: 4110:Classification 4107: 4106: 4104: 4103: 4098: 4093: 4088: 4082: 4080: 4076: 4075: 4073: 4072: 4067: 4062: 4057: 4052: 4047: 4042: 4037: 4031: 4029: 4025: 4024: 4017: 4016: 4009: 4002: 3994: 3985: 3984: 3981: 3980: 3977: 3976: 3974: 3973: 3968: 3963: 3958: 3953: 3948: 3943: 3937: 3935: 3925: 3924: 3911: 3910: 3907: 3906: 3903: 3902: 3900: 3899: 3894: 3889: 3884: 3879: 3874: 3869: 3864: 3863: 3862: 3857: 3852: 3847: 3836: 3834: 3833:(EC 2.7.11.30) 3827: 3826: 3824: 3823: 3819: 3817: 3816:(EC 2.7.11.29) 3810: 3809: 3807: 3806: 3802: 3800: 3799:(EC 2.7.11.28) 3793: 3792: 3790: 3789: 3785: 3783: 3782:(EC 2.7.11.27) 3776: 3775: 3773: 3772: 3767: 3762: 3756: 3754: 3753:(EC 2.7.11.26) 3747: 3746: 3744: 3743: 3738: 3733: 3732: 3731: 3726: 3721: 3716: 3711: 3706: 3701: 3691: 3690: 3689: 3684: 3679: 3674: 3664: 3663: 3662: 3657: 3652: 3647: 3642: 3637: 3632: 3627: 3616: 3614: 3613:(EC 2.7.11.25) 3607: 3606: 3604: 3603: 3602: 3601: 3596: 3591: 3581: 3580: 3579: 3574: 3569: 3559: 3558: 3557: 3552: 3547: 3542: 3537: 3532: 3527: 3516: 3514: 3513:(EC 2.7.11.24) 3507: 3506: 3504: 3503: 3498: 3493: 3488: 3483: 3478: 3473: 3468: 3463: 3457: 3455: 3454:(EC 2.7.11.23) 3448: 3447: 3445: 3444: 3439: 3434: 3429: 3424: 3419: 3414: 3409: 3404: 3399: 3394: 3389: 3384: 3379: 3374: 3369: 3364: 3359: 3354: 3348: 3346: 3345:(EC 2.7.11.22) 3339: 3338: 3336: 3335: 3330: 3325: 3320: 3314: 3312: 3311:(EC 2.7.11.21) 3301: 3300: 3287: 3286: 3283: 3282: 3279: 3278: 3276: 3275: 3270: 3265: 3260: 3254: 3252: 3251:(EC 2.7.11.21) 3245: 3244: 3242: 3241: 3236: 3230: 3228: 3227:(EC 2.7.11.20) 3221: 3220: 3218: 3217: 3212: 3207: 3202: 3197: 3191: 3189: 3188:(EC 2.7.11.19) 3182: 3181: 3179: 3178: 3173: 3168: 3163: 3157: 3155: 3154:(EC 2.7.11.18) 3148: 3147: 3145: 3144: 3139: 3134: 3129: 3124: 3119: 3114: 3109: 3104: 3099: 3094: 3089: 3084: 3079: 3074: 3069: 3064: 3059: 3054: 3049: 3044: 3039: 3034: 3029: 3024: 3019: 3014: 3009: 3004: 2999: 2994: 2989: 2984: 2979: 2974: 2969: 2964: 2959: 2954: 2949: 2944: 2939: 2934: 2929: 2924: 2919: 2914: 2909: 2904: 2899: 2894: 2889: 2884: 2879: 2874: 2869: 2863: 2861: 2860:(EC 2.7.11.17) 2854: 2853: 2851: 2850: 2845: 2840: 2834: 2832: 2831:(EC 2.7.11.16) 2825: 2824: 2822: 2821: 2816: 2810: 2808: 2807:(EC 2.7.11.15) 2801: 2800: 2798: 2797: 2791: 2789: 2788:(EC 2.7.11.14) 2782: 2781: 2779: 2778: 2773: 2768: 2763: 2758: 2753: 2748: 2743: 2738: 2733: 2728: 2723: 2718: 2712: 2710: 2709:(EC 2.7.11.13) 2703: 2702: 2700: 2699: 2694: 2688: 2686: 2685:(EC 2.7.11.12) 2679: 2678: 2676: 2675: 2670: 2665: 2660: 2655: 2649: 2647: 2646:(EC 2.7.11.11) 2640: 2639: 2637: 2636: 2631: 2626: 2621: 2616: 2611: 2605: 2603: 2602:(EC 2.7.11.10) 2596: 2595: 2593: 2592: 2588: 2586: 2579: 2578: 2576: 2575: 2570: 2564: 2562: 2555: 2554: 2552: 2551: 2550: 2549: 2544: 2539: 2528: 2526: 2519: 2518: 2516: 2515: 2509: 2507: 2500: 2499: 2497: 2496: 2491: 2486: 2481: 2475: 2473: 2466: 2465: 2463: 2462: 2457: 2452: 2446: 2444: 2437: 2436: 2434: 2433: 2432: 2431: 2426: 2421: 2413: 2412: 2411: 2406: 2398: 2397: 2396: 2391: 2379: 2377: 2370: 2369: 2367: 2366: 2361: 2356: 2351: 2345: 2343: 2336: 2335: 2333: 2332: 2331: 2330: 2320: 2319: 2318: 2313: 2308: 2303: 2293: 2288: 2283: 2282: 2281: 2276: 2271: 2261: 2256: 2251: 2246: 2241: 2236: 2231: 2226: 2221: 2216: 2211: 2205: 2203: 2192: 2191: 2178: 2177: 2161: 2160: 2153: 2146: 2138: 2131: 2130: 2085: 2042: 2007: 1972: 1937: 1894: 1865: 1836: 1801: 1758: 1723: 1710:10.1038/ng1285 1688: 1659: 1630: 1577: 1548: 1513: 1495:(9): 1739–50. 1484: 1464:(6): 4276–86. 1449: 1419: 1417: 1414: 1413: 1412: 1380: 1379: 1336: 1317:(3): 811–816. 1300: 1283: 1265: 1247: 1226: 1204: 1203: 1201: 1198: 1185: 1182: 1162:leucine zipper 1130: 1129: 1126: 1125: 1120: 1110: 1109: 1103: 1102: 1099: 1098: 1096: 1094: 1087: 1086: 1079: 1072: 1068: 1067: 1064: 1063: 1045: 1044: 1038: 1035: 1034: 1020: 1019: 1013: 1009: 1008: 1005: 1004: 986: 985: 979: 976: 975: 961: 960: 954: 950: 949: 946: 945: 937: 936: 930: 927: 926: 918: 917: 911: 905: 904: 901: 900: 892: 891: 885: 882: 881: 873: 872: 866: 860: 859: 856: 855: 847: 846: 840: 837: 836: 828: 827: 821: 815: 814: 809: 804: 800: 799: 789: 788: 785: 784: 773: 772: 770: 769: 764: 759: 754: 749: 744: 739: 734: 729: 724: 719: 714: 709: 704: 699: 694: 689: 684: 678: 676: 672: 671: 669: 668: 663: 658: 652: 650: 646: 645: 643: 642: 637: 632: 627: 622: 617: 612: 607: 602: 597: 592: 586: 584: 580: 579: 569: 568: 565: 564: 561: 560: 552: 551: 540: 534: 533: 530: 529: 521: 520: 517: 516: 514: 513: 509: 505: 501: 497: 493: 489: 485: 481: 477: 473: 470: 469: 458: 455: 454: 452: 451: 447: 443: 439: 435: 434:saphenous vein 431: 430:body of tongue 427: 423: 422:biceps brachii 419: 415: 411: 408: 407: 395: 394: 386: 375: 369: 368: 365:RNA expression 357: 356: 353: 352: 344: 340: 339: 331: 328: 323: 317: 316: 307: 300: 294: 290: 289: 284: 278: 277: 269: 268: 256: 255: 252: 251: 243: 239: 238: 230: 227: 222: 216: 215: 206: 199: 193: 189: 188: 181: 175: 174: 166: 165: 153: 152: 109: 105: 104: 96: 88: 87: 83: 82: 79: 78: 75: 74: 64: 63: 55: 54: 43: 37: 36: 28: 27: 24: 23: 15: 9: 6: 4: 3: 2: 4399: 4388: 4385: 4383: 4380: 4378: 4375: 4374: 4372: 4361: 4356: 4354: 4349: 4347: 4342: 4341: 4335: 4333: 4329: 4325: 4321: 4316: 4313: 4309: 4308: 4304: 4298: 4293: 4288: 4287: 4284: 4270: 4266: 4265: 4260: 4257: 4253: 4252: 4247: 4244: 4240: 4239: 4234: 4231: 4227: 4226: 4221: 4218: 4214: 4213: 4208: 4205: 4201: 4200: 4195: 4192: 4188: 4187: 4182: 4181: 4179: 4175: 4169: 4166: 4164: 4161: 4159: 4156: 4154: 4151: 4149: 4146: 4145: 4143: 4139: 4133: 4130: 4128: 4127:Enzyme family 4125: 4123: 4120: 4118: 4115: 4114: 4112: 4108: 4102: 4099: 4097: 4094: 4092: 4091:Cooperativity 4089: 4087: 4084: 4083: 4081: 4077: 4071: 4068: 4066: 4063: 4061: 4058: 4056: 4053: 4051: 4050:Oxyanion hole 4048: 4046: 4043: 4041: 4038: 4036: 4033: 4032: 4030: 4026: 4022: 4015: 4010: 4008: 4003: 4001: 3996: 3995: 3992: 3972: 3969: 3967: 3964: 3962: 3959: 3957: 3954: 3952: 3949: 3947: 3944: 3942: 3939: 3938: 3936: 3934: 3930: 3926: 3921: 3916: 3912: 3898: 3895: 3893: 3890: 3888: 3885: 3883: 3880: 3878: 3875: 3873: 3870: 3868: 3865: 3861: 3858: 3856: 3853: 3851: 3848: 3846: 3843: 3842: 3841: 3838: 3837: 3835: 3832: 3828: 3821: 3820: 3818: 3815: 3811: 3804: 3803: 3801: 3798: 3794: 3787: 3786: 3784: 3781: 3777: 3771: 3768: 3766: 3763: 3761: 3758: 3757: 3755: 3752: 3748: 3742: 3739: 3737: 3734: 3730: 3727: 3725: 3722: 3720: 3717: 3715: 3712: 3710: 3707: 3705: 3702: 3700: 3697: 3696: 3695: 3692: 3688: 3685: 3683: 3680: 3678: 3675: 3673: 3670: 3669: 3668: 3665: 3661: 3658: 3656: 3653: 3651: 3648: 3646: 3643: 3641: 3638: 3636: 3633: 3631: 3628: 3626: 3623: 3622: 3621: 3618: 3617: 3615: 3612: 3608: 3600: 3597: 3595: 3592: 3590: 3587: 3586: 3585: 3582: 3578: 3575: 3573: 3570: 3568: 3565: 3564: 3563: 3560: 3556: 3553: 3551: 3548: 3546: 3543: 3541: 3538: 3536: 3533: 3531: 3528: 3526: 3523: 3522: 3521: 3518: 3517: 3515: 3512: 3508: 3502: 3499: 3497: 3494: 3492: 3489: 3487: 3484: 3482: 3479: 3477: 3474: 3472: 3469: 3467: 3464: 3462: 3459: 3458: 3456: 3453: 3449: 3443: 3440: 3438: 3435: 3433: 3430: 3428: 3425: 3423: 3420: 3418: 3415: 3413: 3410: 3408: 3405: 3403: 3400: 3398: 3395: 3393: 3390: 3388: 3385: 3383: 3380: 3378: 3375: 3373: 3370: 3368: 3365: 3363: 3360: 3358: 3355: 3353: 3350: 3349: 3347: 3344: 3340: 3334: 3331: 3329: 3326: 3324: 3321: 3319: 3316: 3315: 3313: 3310: 3306: 3302: 3297: 3292: 3288: 3274: 3271: 3269: 3266: 3264: 3261: 3259: 3256: 3255: 3253: 3250: 3246: 3240: 3237: 3235: 3232: 3231: 3229: 3226: 3222: 3216: 3213: 3211: 3208: 3206: 3203: 3201: 3198: 3196: 3193: 3192: 3190: 3187: 3183: 3177: 3174: 3172: 3169: 3167: 3164: 3162: 3159: 3158: 3156: 3153: 3149: 3143: 3140: 3138: 3135: 3133: 3130: 3128: 3125: 3123: 3120: 3118: 3115: 3113: 3110: 3108: 3105: 3103: 3100: 3098: 3095: 3093: 3090: 3088: 3085: 3083: 3080: 3078: 3075: 3073: 3070: 3068: 3065: 3063: 3060: 3058: 3055: 3053: 3050: 3048: 3045: 3043: 3040: 3038: 3035: 3033: 3030: 3028: 3025: 3023: 3020: 3018: 3015: 3013: 3010: 3008: 3005: 3003: 3000: 2998: 2995: 2993: 2990: 2988: 2985: 2983: 2980: 2978: 2975: 2973: 2970: 2968: 2965: 2963: 2960: 2958: 2955: 2953: 2950: 2948: 2945: 2943: 2940: 2938: 2935: 2933: 2930: 2928: 2925: 2923: 2920: 2918: 2915: 2913: 2910: 2908: 2905: 2903: 2900: 2898: 2895: 2893: 2890: 2888: 2885: 2883: 2880: 2878: 2875: 2873: 2870: 2868: 2865: 2864: 2862: 2859: 2855: 2849: 2846: 2844: 2841: 2839: 2836: 2835: 2833: 2830: 2826: 2820: 2817: 2815: 2812: 2811: 2809: 2806: 2802: 2796: 2793: 2792: 2790: 2787: 2783: 2777: 2774: 2772: 2769: 2767: 2764: 2762: 2759: 2757: 2754: 2752: 2749: 2747: 2744: 2742: 2739: 2737: 2734: 2732: 2729: 2727: 2724: 2722: 2719: 2717: 2714: 2713: 2711: 2708: 2704: 2698: 2695: 2693: 2690: 2689: 2687: 2684: 2680: 2674: 2671: 2669: 2666: 2664: 2661: 2659: 2656: 2654: 2651: 2650: 2648: 2645: 2641: 2635: 2632: 2630: 2627: 2625: 2622: 2620: 2617: 2615: 2612: 2610: 2607: 2606: 2604: 2601: 2597: 2590: 2589: 2587: 2585:(EC 2.7.11.9) 2584: 2580: 2574: 2571: 2569: 2566: 2565: 2563: 2561:(EC 2.7.11.8) 2560: 2556: 2548: 2545: 2543: 2540: 2538: 2535: 2534: 2533: 2532:Aurora kinase 2530: 2529: 2527: 2525:(EC 2.7.11.7) 2524: 2520: 2514: 2511: 2510: 2508: 2506:(EC 2.7.11.6) 2505: 2501: 2495: 2492: 2490: 2487: 2485: 2482: 2480: 2477: 2476: 2474: 2472:(EC 2.7.11.5) 2471: 2467: 2461: 2458: 2456: 2453: 2451: 2448: 2447: 2445: 2443:(EC 2.7.11.4) 2442: 2438: 2430: 2427: 2425: 2422: 2420: 2417: 2416: 2414: 2410: 2407: 2405: 2402: 2401: 2399: 2395: 2392: 2390: 2387: 2386: 2384: 2381: 2380: 2378: 2376:(EC 2.7.11.3) 2375: 2371: 2365: 2362: 2360: 2357: 2355: 2352: 2350: 2347: 2346: 2344: 2342:(EC 2.7.11.2) 2341: 2337: 2329: 2326: 2325: 2324: 2321: 2317: 2314: 2312: 2309: 2307: 2304: 2302: 2299: 2298: 2297: 2296:EIF-2 kinases 2294: 2292: 2289: 2287: 2284: 2280: 2277: 2275: 2272: 2270: 2267: 2266: 2265: 2262: 2260: 2257: 2255: 2252: 2250: 2247: 2245: 2242: 2240: 2237: 2235: 2232: 2230: 2227: 2225: 2222: 2220: 2217: 2215: 2212: 2210: 2207: 2206: 2204: 2202:(EC 2.7.11.1) 2201: 2197: 2193: 2188: 2183: 2179: 2174: 2170: 2166: 2159: 2154: 2152: 2147: 2145: 2140: 2139: 2136: 2127: 2123: 2119: 2115: 2111: 2107: 2103: 2099: 2095: 2091: 2086: 2082: 2078: 2073: 2068: 2064: 2060: 2056: 2052: 2048: 2043: 2039: 2035: 2030: 2025: 2022:(6): 785–95. 2021: 2017: 2013: 2008: 2004: 2000: 1995: 1990: 1986: 1982: 1981:J. Biol. Chem 1978: 1973: 1969: 1965: 1960: 1955: 1951: 1947: 1946:J. Biol. Chem 1943: 1938: 1934: 1930: 1925: 1920: 1916: 1912: 1908: 1904: 1900: 1895: 1891: 1887: 1883: 1879: 1876:(3): 973–80. 1875: 1871: 1866: 1862: 1858: 1854: 1850: 1847:(1): 424–31. 1846: 1842: 1837: 1833: 1829: 1824: 1819: 1815: 1811: 1810:J. Biol. Chem 1807: 1802: 1798: 1794: 1790: 1786: 1781: 1776: 1772: 1768: 1764: 1759: 1755: 1751: 1746: 1741: 1737: 1733: 1729: 1724: 1720: 1716: 1711: 1706: 1702: 1698: 1694: 1689: 1685: 1681: 1677: 1673: 1669: 1665: 1660: 1656: 1652: 1648: 1644: 1640: 1636: 1631: 1627: 1623: 1618: 1613: 1608: 1603: 1599: 1595: 1591: 1587: 1583: 1578: 1574: 1570: 1566: 1562: 1559:(1): 105–10. 1558: 1554: 1549: 1545: 1541: 1536: 1531: 1527: 1523: 1522:J. Biol. Chem 1519: 1514: 1510: 1506: 1502: 1498: 1494: 1490: 1485: 1481: 1477: 1472: 1467: 1463: 1459: 1458:J. Biol. Chem 1455: 1450: 1446: 1442: 1438: 1434: 1430: 1426: 1421: 1420: 1409: 1405: 1401: 1397: 1393: 1389: 1384: 1383: 1375: 1371: 1367: 1363: 1359: 1355: 1351: 1347: 1340: 1332: 1328: 1324: 1320: 1316: 1312: 1304: 1296: 1290: 1288: 1279: 1275: 1269: 1261: 1257: 1251: 1244: 1240: 1235: 1233: 1231: 1223: 1219: 1214: 1212: 1210: 1205: 1197: 1195: 1191: 1181: 1179: 1178:pro-apoptotic 1175: 1171: 1167: 1163: 1159: 1155: 1151: 1146: 1144: 1141:, is a human 1140: 1136: 1124: 1119: 1115: 1111: 1108: 1104: 1097: 1095: 1092: 1088: 1084: 1080: 1077: 1073: 1069: 1062: 1060: 1056: 1052: 1046: 1042: 1039: 1033: 1031: 1027: 1021: 1017: 1014: 1010: 1003: 1001: 997: 993: 987: 983: 980: 974: 972: 968: 962: 958: 955: 953:RefSeq (mRNA) 951: 944: 943: 938: 934: 931: 925: 924: 919: 915: 912: 910: 906: 899: 898: 893: 889: 886: 880: 879: 874: 870: 867: 865: 861: 854: 853: 848: 844: 841: 835: 834: 829: 825: 822: 820: 816: 813: 810: 808: 805: 801: 798: 794: 790: 783: 779: 774: 768: 765: 763: 760: 758: 755: 753: 750: 748: 745: 743: 740: 738: 735: 733: 730: 728: 725: 723: 720: 718: 715: 713: 710: 708: 705: 703: 700: 698: 695: 693: 690: 688: 685: 683: 680: 679: 677: 674: 673: 667: 664: 662: 659: 657: 654: 653: 651: 648: 647: 641: 638: 636: 633: 631: 628: 626: 623: 621: 618: 616: 613: 611: 608: 606: 603: 601: 598: 596: 593: 591: 588: 587: 585: 582: 581: 578: 577:Gene ontology 574: 570: 558: 553: 549: 544: 541: 539: 535: 527: 522: 511: 507: 504:soleus muscle 503: 499: 495: 491: 487: 483: 479: 475: 474: 471: 467: 462: 459: 449: 445: 441: 437: 433: 429: 425: 421: 417: 413: 412: 409: 405: 400: 397: 396: 393: 391: 387: 385: 384: 380: 379: 376: 374: 370: 366: 362: 358: 350: 345: 341: 337: 332: 322: 318: 311: 304: 298: 291: 283: 279: 275: 270: 266: 261: 257: 249: 244: 240: 236: 231: 221: 217: 210: 203: 197: 190: 186: 180: 176: 172: 167: 163: 158: 154: 150: 146: 142: 138: 134: 130: 126: 122: 118: 114: 106: 101: 94: 89: 84: 73: 71: 65: 60: 57: 56: 52: 49: 42: 38: 33: 29: 25: 20: 4332:expanding it 4324:chromosome 2 4317: 4302: 4264:Translocases 4261: 4248: 4235: 4222: 4209: 4199:Transferases 4196: 4183: 4040:Binding site 3728: 3471:P70S6 kinase 2093: 2089: 2054: 2050: 2019: 2015: 1984: 1980: 1949: 1945: 1906: 1902: 1873: 1869: 1844: 1840: 1813: 1809: 1770: 1766: 1735: 1731: 1700: 1696: 1670:(2): 181–7. 1667: 1663: 1638: 1634: 1589: 1585: 1556: 1552: 1525: 1521: 1492: 1488: 1461: 1457: 1431:(3): 811–6. 1428: 1424: 1394:(1): 25–34. 1391: 1387: 1349: 1345: 1339: 1314: 1310: 1303: 1277: 1268: 1259: 1250: 1187: 1184:Interactions 1164:motif and a 1147: 1138: 1134: 1133: 1051:NP_001158263 1048: 1023: 992:NM_001164791 989: 964: 940: 921: 895: 876: 850: 831: 811: 806: 388: 381: 246:173,268,015 233:173,075,435 108:External IDs 67: 4035:Active site 3922:(EC 2.7.12) 3309:Polo kinase 3249:Polo kinase 1703:(1): 40–5. 1641:(1): 71–7. 1352:(1): 71–7. 640:RNA binding 630:ATP binding 347:72,272,954 334:72,115,981 326:2|2 C3 86:Identifiers 4371:Categories 4238:Isomerases 4212:Hydrolases 4079:Regulation 2600:IκB kinase 2175:2.7.11-12) 1903:Genome Res 1767:Curr. Biol 1732:Cancer Res 1697:Nat. Genet 1664:J. Biochem 1245:, May 2017 1224:, May 2017 1200:References 1170:homodimers 1158:N-terminal 1152:family of 732:cell cycle 712:cell death 392:(ortholog) 129:HomoloGene 4382:EC 2.7.11 4322:on human 4117:EC number 2726:PKC alpha 1366:0006-291X 1059:NP_835185 1055:NP_075544 1030:NP_598407 1026:NP_057737 1000:NM_178084 996:NM_023057 971:NM_133646 967:NM_016653 797:Orthologs 661:cytoplasm 442:vena cava 137:GeneCards 4141:Kinetics 4065:Cofactor 4028:Activity 3082:KIAA0999 2977:MAPKAPK5 2972:MAPKAPK3 2967:MAPKAPK2 2118:16189514 2081:15815621 2038:15778465 2003:15737997 1968:15684425 1933:15489334 1890:15485649 1861:15465036 1832:15342622 1789:15324660 1754:15172994 1719:14702039 1684:12761180 1655:12535642 1626:12477932 1573:12220515 1544:11836244 1509:11549352 1480:11042189 1445:10924358 1408:29374956 1374:12535642 1331:10924358 1241:– 1220:– 1190:interact 1107:Wikidata 776:Sources: 4297:Biology 4251:Ligases 4021:Enzymes 3741:MAP3K14 3719:MAP3K11 3714:MAP3K10 3704:MAP3K13 3699:MAP3K12 3501:RPS6KC1 3496:RPS6KA1 3491:RPS6KA3 3486:RPS6KA2 3481:RPS6KB2 3466:RPS6KA4 3461:RPS6KA5 3112:Kalirin 3077:SNF1LK2 2316:EIF2AK4 2311:EIF2AK3 2165:Kinases 2126:4427026 2098:Bibcode 2059:Bibcode 1797:2371325 1594:Bibcode 1243:Ensembl 1222:Ensembl 909:UniProt 864:Ensembl 803:Species 782:QuickGO 666:cytosol 656:nucleus 446:urethra 367:pattern 141:MAP3K20 125:2443258 100:MAP3K20 93:Aliases 22:MAP3K20 4283:Portal 4225:Lyases 3971:MAP2K7 3966:MAP2K6 3961:MAP2K5 3956:MAP2K4 3951:MAP2K3 3946:MAP2K2 3941:MAP2K1 3892:ACVRL1 3887:ACVR2B 3882:ACVR2A 3877:ACVR1C 3872:ACVR1B 3855:BMPR1B 3850:BMPR1A 3724:MAP3K7 3709:MAP3K9 3660:MAP3K8 3655:MAP3K7 3650:MAP3K6 3645:MAP3K5 3640:MAP3K4 3635:MAP3K3 3630:MAP3K2 3625:MAP3K1 3599:MAPK14 3594:MAPK13 3589:MAPK11 3577:MAPK10 3555:MAPK15 3550:MAPK12 3442:CDC2L1 3417:CDC2L5 3092:SNF1LK 2917:CAMK2G 2912:CAMK2D 2907:CAMK2B 2902:CAMK2A 2892:CAMK1G 2887:CAMK1D 2882:CAMK1B 2877:CAMK1A 2731:PRKCB1 2668:PRKACA 2663:PRKACB 2658:PRKACG 2634:IKBKAP 2460:BCKDHB 2455:BCKDHA 2429:PRKAG3 2424:PRKAG2 2419:PRKAG1 2409:PRKAB2 2404:PRKAB1 2394:PRKAA2 2389:PRKAA1 2234:STK38L 2124:  2116:  2090:Nature 2079:  2051:Nature 2036:  2001:  1966:  1931:  1924:528928 1921:  1888:  1859:  1830:  1795:  1787:  1752:  1717:  1682:  1653:  1624:  1617:139241 1614:  1571:  1542:  1507:  1478:  1443:  1406:  1372:  1364:  1329:  1194:ZNF33A 1150:MAPKKK 1093:search 1091:PubMed 942:Q9ESL4 923:Q9NYL2 819:Entrez 538:BioGPS 225:2q31.1 117:609479 4326:is a 4177:Types 3933:MAP2K 3867:ACVR1 3860:BMPR2 3845:BMPR1 3770:GSK-3 3611:MAP3K 3572:MAPK9 3567:MAPK8 3545:MAPK7 3540:MAPK6 3535:MAPK4 3530:MAPK3 3525:MAPK1 3437:PFTK1 3432:PCTK3 3427:PCTK2 3422:PCTK1 3412:CDK12 3407:CDK10 3382:CDKL5 3362:CDKL2 3239:STK19 3234:EEF2K 3215:PHKG2 3210:PHKG1 3200:PHKA2 3195:PHKA1 3176:MYLK4 3171:MYLK3 3166:MYLK2 3142:DCLK1 3137:Titin 3127:TRIB3 3122:TRIB2 3117:TRIB1 3107:TSSK2 3087:STK40 3072:PSKH1 3067:PRKD3 3062:PRKD2 3042:PHKG2 3037:PHKG1 3027:OBSCN 3022:NUAK2 3017:NUAK1 3012:MKNK2 3007:MKNK1 2997:MARK4 2992:MARK3 2987:MARK2 2982:MARK1 2962:STK11 2957:DAPK3 2952:DAPK2 2947:DAPK1 2942:CHEK2 2937:CHEK1 2922:CAMK4 2897:CAMK2 2872:CAMK1 2867:BRSK2 2761:PRKCQ 2756:PRKCI 2751:PRKCG 2746:PRKCH 2741:PRKCE 2736:PRKCD 2697:PRKG1 2629:IKBKG 2624:IKBKE 2573:STK10 2568:FASTK 2494:IDH3G 2489:IDH3B 2484:IDH3A 2450:BCKDK 2244:ROCK1 2229:STK38 2224:MAST2 2219:MAST1 2214:LATS2 2209:LATS1 2122:S2CID 1793:S2CID 1192:with 852:65964 833:51776 812:Mouse 807:Human 778:Amigo 484:ankle 390:Mouse 383:Human 330:Start 265:Mouse 229:Start 162:Human 133:32331 4328:stub 4320:gene 4269:list 4262:EC7 4256:list 4249:EC6 4243:list 4236:EC5 4230:list 4223:EC4 4217:list 4210:EC3 4204:list 4197:EC2 4191:list 4184:EC1 3760:TPK1 3736:CDC7 3694:MLKs 3687:KSR2 3682:KSR1 3677:BRAF 3672:ARAF 3667:RAFs 3402:CDK9 3397:CDK8 3392:CDK7 3387:CDK6 3377:CDK5 3372:CDK4 3367:CDK3 3357:CDK2 3352:CDK1 3333:PLK4 3328:PLK3 3323:PLK2 3318:PLK1 3273:PLK4 3268:PLK3 3263:PLK2 3258:PLK1 3205:PHKB 3161:MYLK 3132:TRIO 3102:SPEG 3097:SNRK 3057:PKD1 3052:PIM2 3047:PIM1 3032:PASK 3002:MELK 2932:CASK 2927:MLCK 2848:GRK6 2843:GRK5 2838:GRK4 2776:PKN3 2771:PKN2 2673:PRKY 2619:TBK1 2614:IKK2 2609:CHUK 2513:STK4 2479:IDH2 2364:PDK4 2359:PDK3 2354:PDK2 2349:PDK1 2328:WEE1 2323:Wee1 2291:mTOR 2279:AKT3 2274:AKT2 2269:AKT1 2259:SGK3 2254:SGK2 2114:PMID 2077:PMID 2034:PMID 1999:PMID 1964:PMID 1929:PMID 1886:PMID 1857:PMID 1828:PMID 1785:PMID 1750:PMID 1715:PMID 1680:PMID 1651:PMID 1622:PMID 1569:PMID 1540:PMID 1505:PMID 1476:PMID 1441:PMID 1404:PMID 1370:PMID 1362:ISSN 1327:PMID 1143:gene 373:Bgee 321:Band 282:Chr. 220:Band 179:Chr. 113:OMIM 70:5HES 51:RCSB 48:PDBe 3765:TTK 3729:ZAK 2306:HRI 2301:PKR 2249:SGK 2239:CIT 2106:doi 2094:437 2067:doi 2055:434 2024:doi 1989:doi 1985:280 1954:doi 1950:280 1919:PMC 1911:doi 1878:doi 1874:324 1849:doi 1845:324 1818:doi 1814:279 1775:doi 1740:doi 1705:doi 1672:doi 1668:133 1643:doi 1639:301 1612:PMC 1602:doi 1561:doi 1557:297 1530:doi 1526:277 1497:doi 1466:doi 1462:276 1433:doi 1429:274 1396:doi 1354:doi 1350:301 1319:doi 1315:274 1139:ZAK 343:End 242:End 145:OMA 121:MGI 41:PDB 4373:: 2415:γ 2400:β 2385:α 2173:EC 2167:: 2120:. 2112:. 2104:. 2092:. 2075:. 2065:. 2053:. 2049:. 2032:. 2018:. 2014:. 1997:. 1983:. 1979:. 1962:. 1948:. 1944:. 1927:. 1917:. 1907:14 1905:. 1901:. 1884:. 1872:. 1855:. 1843:. 1826:. 1812:. 1808:. 1791:. 1783:. 1771:14 1769:. 1765:. 1748:. 1736:64 1734:. 1730:. 1713:. 1701:36 1699:. 1695:. 1678:. 1666:. 1649:. 1637:. 1620:. 1610:. 1600:. 1590:99 1588:. 1584:. 1567:. 1555:. 1538:. 1524:. 1520:. 1503:. 1493:33 1491:. 1474:. 1460:. 1456:. 1439:. 1427:. 1402:. 1392:61 1390:. 1368:. 1360:. 1348:. 1325:. 1313:. 1286:^ 1276:. 1258:. 1229:^ 1208:^ 1196:. 1145:. 780:/ 349:bp 336:bp 248:bp 235:bp 143:; 139:: 135:; 131:: 127:; 123:: 119:; 115:: 4359:e 4352:t 4345:v 4334:. 4285:: 4271:) 4267:( 4258:) 4254:( 4245:) 4241:( 4232:) 4228:( 4219:) 4215:( 4206:) 4202:( 4193:) 4189:( 4013:e 4006:t 3999:v 3822:- 3805:- 3788:- 2591:- 2171:( 2157:e 2150:t 2143:v 2128:. 2108:: 2100:: 2083:. 2069:: 2061:: 2040:. 2026:: 2020:4 2005:. 1991:: 1970:. 1956:: 1935:. 1913:: 1892:. 1880:: 1863:. 1851:: 1834:. 1820:: 1799:. 1777:: 1756:. 1742:: 1721:. 1707:: 1686:. 1674:: 1657:. 1645:: 1628:. 1604:: 1596:: 1575:. 1563:: 1546:. 1532:: 1511:. 1499:: 1482:. 1468:: 1447:. 1435:: 1410:. 1398:: 1376:. 1356:: 1333:. 1321:: 1297:. 1280:. 1262:. 267:) 164:) 147::

Index

PDB
PDBe
RCSB
5HES
Aliases
MAP3K20
OMIM
609479
MGI
2443258
HomoloGene
32331
GeneCards
MAP3K20
OMA
MAP3K20 - orthologs
Human
Chromosome 2 (human)
Chr.
Chromosome 2 (human)
Chromosome 2 (human)
Genomic location for MAP3K20
Genomic location for MAP3K20
Band
bp
bp
Mouse
Chromosome 2 (mouse)
Chr.
Chromosome 2 (mouse)

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