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107:. One conspicuous difference between SMILE and LASIK is the size and shape of the corneal incision. In LASIK, the surgeon performs a 270-degree, 20 mm long incision, while in SMILE the so-called "side cap cut", which is the incision through which the surgeon extracts the lenticule, is usually about 4 mm long. Currently in the US the procedure is only approved for nearsightedness, but is used for
119:
astigmatism. Some theoretical advantages are that the technique is minimally invasive compared with other flap based treatments and no collateral damage occurs to surrounding tissue due to the high speed of the femtosecond laser. There are limited studies on corneal wound healing and inflammatory response after this treatment has been carried out. There is a suggestion that the expression of
103:
anterior one. The minimum lenticule edge thickness is usually set at 15 µm, to avoid the risk of lenticule rupturing during detachment and subsequent extraction. The method of extraction was via a LASIK-type flap in ReLEx FLEx, but in SMILE a flapless technique makes a small tunnel incision in the corneal periphery, that does not (mostly) destroy
135:
As lenticule extraction techniques evolve, there is a possibility that extracted lenticules can be cryogenically preserved either for future donation, or re-implantation. Proof of concept has been carried out on primates where lenticules were extracted from monkeys and allogenically transplanted into
123:
which is associated with wound healing is less in this method compared with femtosecond-LASIK. Because SMILE treatment is relatively new compared with other laser correction treatments, result studies are limited, but postoperative five year (SMILE) outcomes indicate that the results have been stable
102:
laser-tissue interaction. The posterior intrastromal plane is created first and the anterior plane second. To allow better separation, the two lenticule faces are cut by the laser head moving in a spiral fashion - conventionally outside in for the posterior face and respectively inside out for the
118:
has separated the lenticule, a blunt spatula is inserted through the incision between the lenticule and the stroma and carefully rotated to ensure that the lenticule is completely detached prior to removal by forceps. The procedure has been described as safe and predictable in treating myopia and
553:
545:
416:
Blum, Marcus; Täubig, Kathrin; Gruhn, Christin; Sekundo, Walter; Kunert, Kathleen S (2016). "Five-year results of Small
Incision Lenticule Extraction (ReLEx SMILE)".
87:
laser surgery, the intrastromal procedure uses a single femtosecond laser referenced to the corneal surface to cleave a thin lenticule from the
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https://rexhamiltonmd.com/pdfs/peer%20reviewed%20papers%20and%20review%20articles/SMILE%20vs%20LASIK%20early%20US%20outcomes%20jcrs%202021.pdf
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Shah R, Shah S, Sengupta S (2011). "Results of small incision lenticule extraction: All-in-one femtosecond laser refractive surgery".
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504:"Femtosecond Laser-Assisted Corneal Small Incision Allogenic Intrastromal Lenticule Implantation in Monkeys: A Pilot Study"
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Moshirfar M, McCaughey MV, Reinstein DZ, Shah R, Santiago-Caban L, Fenzl CR (2015). "Small-incision lenticule extraction".
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Ang, Marcus; Chaurasia, Shyam S.; Angunawela, Romesh I.; Poh, Rebekah; Riau, Andri; Tan, Donald; Mehta, Jodhbir S. (2012).
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279:"Femtosecond Lenticule Extraction (FLEx): Clinical Results, Interface Evaluation, and Intraocular Pressure Variation"
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Small
Incision Lenticule Extraction (SMILE): Principles, Techniques, Complication Management, and Future Concepts
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low-energy SMILE, high-energy SMILE and LASIK for myopia and myopic astigmatism in the United States]
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to be extracted is accurately cut to the correction prescription required by the patient using a
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https://rexhamiltonmd.com/wp-content/uploads/2019/07/0319CRST_Zeiss-hamilton_Insert.pdf
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after 5 years of follow-up. In some cases post operative tear secretion and
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Liu R, Zhao J, Xu Y, Li M, Niu L, Liu H, Sun L, Chu R, Zhou X (2015).
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Incision
Lenticule Extraction (SMILE) | Official Zeiss Publication]
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159:"New Developments in the Lenticule Extraction Procedure"
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have been observed along with similar post operative
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283:Investigative Ophthalmology & Visual Science
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356:"SMILE (small incision lenticle extraction)"
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157:Ivarsen, Anders; Hjortdal, Jesper (2014).
16:Form of laser based refractive eye surgery
556:Comparison of early visual outcomes after
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1203:Optical coherence tomography angiography
1615:Multiple-prism grating laser oscillator
1002:Pre-Descemet's endothelial keratoplasty
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886:Manual small incision cataract surgery
568:Frequently Asked Questions About Small
328:"The Current State of SMILE vs. LASIK"
326:Stephenson, Michelle (15 April 2021).
226:Tityal, Jeewan S. (5 September 2018).
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61:ReLEx Femtosecond lenticule extraction
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1133:Botulinum toxin therapy of strabismus
1126:Minimally invasive strabismus surgery
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136:other monkeys with positive results.
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821:Phakic intraocular lens implantation
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956:Minimally invasive glaucoma surgery
53:Small incision lenticule extraction
22:Small incision lenticule extraction
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779:Intrastromal corneal ring segment
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430:10.1136/bjophthalmol-2015-306822
418:British Journal of Ophthalmology
754:Automated lamellar keratoplasty
1524:Amplified spontaneous emission
1235:Bagolini Striated Glasses Test
1030:Corneal collagen cross-linking
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219:
1:
1193:Indocyanine green angiography
1188:Heidelberg Retinal Tomography
1020:Anterior chamber paracentesis
201:Walter Sekundo (2015-08-03).
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1689:. You can help Knowledge by
1198:Optical coherence tomography
1077:Phototherapeutic keratectomy
951:Excimer laser trabeculostomy
508:Invest. Ophthalmol. Vis. Sci
67:), is a form of laser based
7:
1580:Chirped pulse amplification
826:Photorefractive keratectomy
10:
1757:
1668:
1384:List of laser applications
1361:
1245:Dilated fundus examination
1225:A-scan ultrasound biometry
799:Laser thermal keratoplasty
622:Anesthesia for eye surgery
481:10.1016/j.jcrs.2015.02.006
387:10.1016/j.jcrs.2010.07.033
176:10.17925/EOR.2014.08.01.31
163:European Ophthalmic Review
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671:East Asian blepharoplasty
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111:too in other countries.
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205:. Springer. p. 15.
59:), second generation of
1178:Fluorescein angiography
1025:Boston keratoprosthesis
987:Corneal transplantation
759:Conductive keratoplasty
469:J Cataract Refract Surg
375:J Cataract Refract Surg
332:Review of Ophthalmology
132:seen in LASIK surgery.
91:for manual extraction.
1374:List of laser articles
1057:Intravitreal injection
921:Laser photocoagulation
866:Glued intraocular lens
232:Clinical Ophthalmology
83:. Although similar to
69:refractive eye surgery
1275:Slit-lamp examination
1240:Color perception test
1163:Electronystagmography
711:Dacryocystorhinostomy
521:10.1167/iovs.14-15296
1736:Refractive surgeries
1549:Population inversion
1116:Harada–Ito procedure
789:Laser blended vision
360:Lasercare Eye Center
296:10.1167/iovs.11-8808
245:10.2147/OPTH.S157172
1600:Laser beam profiler
1519:Active laser medium
1459:Free-electron laser
1379:List of laser types
1300:Plaque radiotherapy
1173:Electroretinography
891:Phacoemulsification
546:Zeiss Official Page
1183:Fundus photography
1168:Electrooculography
1153:Corneal topography
1121:Strabismus surgery
73:Carl Zeiss Meditec
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794:Laser eye surgery
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116:femtosecond laser
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1554:Ultrashort pulse
1544:Lasing threshold
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1158:Electrodiagnosis
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126:dry eye syndrome
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669:
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633:
632:Oculoplastics
630:
629:
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623:
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619:
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612:
608:
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581:
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531:
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486:
482:
478:
475:(3): 652–65.
474:
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463:
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431:
427:
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412:
404:
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381:(1): 127–37.
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238:: 1685–1699.
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133:
131:
130:complications
127:
122:
117:
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109:hypermetropia
106:
101:
97:
92:
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82:
78:
74:
71:developed by
70:
66:
62:
58:
54:
51:
41:
35:
32:Ophthalmology
31:
29:
25:
20:
1691:expanding it
1680:
1610:Mode locking
1563:Laser optics
1047:Evisceration
916:Ignipuncture
835:
716:Punctoplasty
693:Tarsorrhaphy
571:
559:
511:
507:
497:
472:
468:
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421:
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335:. Retrieved
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202:
166:
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134:
113:
93:
64:
60:
56:
52:
49:
48:
1640:Q-switching
1501:X-ray laser
1494:Ti-sapphire
1464:Laser diode
1442:Helium–neon
1270:Retinoscopy
1230:Amsler grid
1217:examination
1106:Extraocular
1035:Enucleation
861:Capsulotomy
627:Eye surgery
121:fibronectin
81:astigmatism
79:, and cure
1730:Categories
1255:Gonioscopy
1250:Funduscopy
1092:Vitrectomy
1087:Sclerotomy
1062:Iridectomy
739:Refractive
607:procedures
605:Tests and
140:References
114:After the
1605:M squared
1427:Gas laser
1410:Dye laser
1290:Radiation
1082:Pterygium
1040:Conformer
774:Epi-LASIK
438:0007-1161
305:1552-5783
185:1756-1795
169:(1): 31.
96:lenticule
28:Specialty
1658:Category
1452:Nitrogen
1316:Couching
1067:Peritomy
936:Glaucoma
846:Cataract
530:26047173
489:25804585
454:23860546
446:26746577
403:43781436
395:21183108
313:22323464
264:30233132
1683:surgery
1437:Excimer
1309:History
1292:therapy
1145:imaging
1143:Medical
1108:muscles
938:surgery
909:surgery
907:Retinal
896:Prechop
848:surgery
741:surgery
658:Eyelids
255:6134409
1479:Nd:YAG
1474:Er:YAG
1415:Bubble
1363:Lasers
649:Adnexa
528:
487:
452:
444:
436:
401:
393:
337:2 July
311:
303:
262:
252:
209:
183:
77:myopia
1681:This
1484:Raman
1013:Other
836:SMILE
804:LASIK
730:Globe
450:S2CID
399:S2CID
85:LASIK
57:SMILE
50:ReLEx
38:[
1687:stub
1489:Ruby
611:eyes
526:PMID
485:PMID
442:PMID
434:ISSN
391:PMID
339:2024
309:PMID
301:ISSN
260:PMID
207:ISBN
181:ISSN
94:The
65:FLEx
1447:Ion
1215:Eye
516:doi
477:doi
426:doi
422:100
383:doi
291:doi
250:PMC
240:doi
171:doi
1732::
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512:56
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473:41
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379:37
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347:^
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287:53
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236:12
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193:^
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167:08
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161:.
147:^
1718:e
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293::
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63:(
55:(
42:]
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