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Richard Lenski

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The program was dubbed Avida and starts with an artificial petri dish where organisms reproduce and perform mathematical calculations to acquire rewards in the form of increased computer time for replication. The program randomly adds mutations to copies of the artificial organisms, whicha re then subject to natural selection. As the artificial life reproduces, different lines adapt and evolve depending on their environments. The program aims to parallel the evolution of biological life in a highly abstracted form and at a much faster speed.
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computer program that allows detailed analyses on the evolution of complex systems. The system allows the user to set the rate of random mutations, while natural selection acts within a virtual world promotes those mutations that provide beneficial traits (and selects against deleterious mutations).
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Tenaillon, O., J. E. Barrick, N. Ribeck, D. E. Deatherage, J. L. Blanchard, A. Dasgupta, G. C. Wu, S. Wielgoss, S. Cruveiller, C. Médigue, D. Schneider, and R. E. Lenski. 2016. Tempo and mode of genome evolution in a 50,000-generation
514:, which Schlafly initiated as a reaction to reports of Lenski's description of the evolution of aerobic citrate usage in one of the long-term evolution experiment populations. These same findings were later cited by the 759:
Tenaillon, Olivier; Barrick, Jeffrey E.; Ribeck, Noah; Deatherage, Daniel E.; Blanchard, Jeffrey L.; Dasgupta, Aurko; Wu, Gabriel C.; Wielgoss, Sébastien; Cruveiller, Stéphane (2016-08-11).
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have occurred in all 12 populations, while others have only appeared in one or a few populations. One particularly striking adaptation was the evolution of a strain of
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Bohannan, B. J. M., and R. E. Lenski. 2000. Linking genetic change to community evolution: insights from studies of bacteria and bacteriophage. 
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Lenski, R. E., and M. Travisano. 1994. Dynamics of adaptation and diversification: a 10,000-generation experiment with bacterial populations. 
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Lenski, R. E., and R. M. May. 1994. The evolution of virulence in parasites and pathogens: reconciliation between two competing hypotheses. 
351:, where he began his work studying microbiology. In 1985, Lenski joined the faculty in the Department of Ecology and Evolutionary Biology at the 560: 1395: 1823: 1588: 568: 467:
In August 2013, having been inspired by a presentation by Titus Brown on the role of social media in science, Lenski began blogging at
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Blount, Z. D., R. E. Lenski, and J. B. Losos. 2018. Contingency and determinism in evolution: replaying life’s tape. 
355:, and he was promoted to associate professor there in 1988. In 1991, Lenski moved his lab to Michigan State University, joining the 1778: 652:
Blount, Z. D., J. E. Barrick, C. J. Davidson, and R. E. Lenski. 2012. Genomic analysis of a key innovation in an experimental
1863: 826:"Adaptation, Clonal Interference, and Frequency-Dependent Interactions in a Long-Term Evolution Experiment with Escherichia coli" 537: 388: 269: 65: 1727: 1168: 1088: 597:
On February 17, 2010, he co-founded the NSF Science and Technology Center for the Study of Evolution in Action, known as the
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Since the experiment's inception, Lenski and his colleagues have reported a wide array of genetic changes; some evolutionary
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Wiser, M. J., N. Ribeck, and R. E. Lenski. 2013. Long-term dynamics of adaptation in asexual populations. 
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Lenski, R. E., C. Ofria, R. T. Pennock, and C. Adami. 2003. The evolutionary origin of complex features. 
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Meyer, Justin R.; Dobias, Devin T.; Medina, Sarah J.; Servilio, Lisa; Gupta, Animesh; Lenski, Richard E. (2016-11-24).
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This article is about Richard Lenski, the evolutionary biologist. For the Lutheran commentator (his ancestor), see
1828: 541: 364: 1325:"Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli" 918:"Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli" 605: 347:
After completing his doctoral degree, Lenski did postdoctoral research in the laboratory of Bruce Levin at the
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led by Richard Lenski that has been tracking genetic changes in 12 initially identical populations of asexual
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bacteria since 24 February 1988. The populations reached the milestone of 75,000 generations in 2022.
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https://telliamedrevisited.wordpress.com/2014/02/07/zachary-blount-on-ham-on-nye-debate-follow-up-3/
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Richard E. Lenski; Charles Ofria; Claus O. Wilke; Jia Lan Wang & Christoph Adami (2001-07-19).
1487: 1466: 285: 1442: 1080: 1838: 1808: 1689: 1254:"Historical contingency and the evolution of a key innovation in an experimental population of 1198: 410: 120: 1623: 1509: 533:. Lenski strongly criticized Ham's citation of his work and the conclusions Ham drew from it. 556: 483: 97: 1798: 1524: 1410: 1336: 1269: 1210: 1045: 996: 929: 772: 720: 360: 328: 245: 117: 90: 20: 276:, which has been instrumental in understanding the core processes of evolution, including 8: 1510:"Evolution of digital organisms at high mutation rates leads to survival of the flattest" 881:
Lenski, R. E. (1998-12-01). "Bacterial evolution and the cost of antibiotic resistance".
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Lenski's research has received considerable attention, including lengthy discussion in
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Science and Technology Center for Microbial Ecology there. Lenski did sabbaticals at
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https://telliamedrevisited.wordpress.com/2014/02/06/ham-on-nye-debate-follow-up-2/
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https://telliamedrevisited.wordpress.com/2014/02/05/ham-on-nye-debate-follow-up-1/
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Blount, Zachary D.; Borland, Christina Z.; Lenski, Richard E. (2008-06-10).
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is its inability to use citrate as an energy source under oxic conditions.
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as a carbon source in an aerobic environment. A defining characteristic of
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and the poet Jean Lenski. He is also the great-nephew of children's author
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Maddamsetti, Rohan; Lenski, Richard E.; Barrick, Jeffrey E. (2015-06-01).
586:, and he holds the title of the John A. Hannah Distinguished Professor of 1391: 985:"Ecological speciation of bacteriophage lambda in allopatry and sympatry" 611:
Lenski was the recipient of the 2021 Lifetime Achievement Award from the
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Blount, Zachary; Borland, Christina; Lenski, Richard (June 10, 2008).
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Blount, Zachary D.; Borland, Christina Z.; Lenski, Richard E. (2008).
761:"Tempo and mode of genome evolution in a 50,000-generation experiment" 1536: 734: 289: 1488:"Artificial life experiments show how complex functions can evolve" 530: 324: 151:
Effects of competition and disturbance on ground beetle populations
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Richard Lenski with Long-Term Flasks and Incubator on May 26, 2016
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How Evolution Shapes Our Lives: Essays on Biology and Society
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Members of the United States National Academy of Sciences
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United States National Academy of Sciences member list,
1467:"Digital organisms used to confirm evolutionary process" 823: 230: 1381: 707:"MSU's Richard Lenski wins 2017 Friend of Darwin award" 409:
long-term evolution experiment is an ongoing study in
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Proceedings of the National Academy of Sciences, USA
1322: 1251: 1079:(7 ed.). Pearson, Benjamin Cummings. pp.  915: 547:video, which has been viewed over 6 million times. 1834:University of North Carolina at Chapel Hill alumni 1774:BEACON Center for the Study of Evolution in Action 1072: 1128:Lenski, Richard E.; May, Robert M. (1994-08-07). 682:. Princeton University Press, Princeton, NJ. 1790: 678:Losos, J. B., and R. E. Lenski, eds. 2016. 1574: 1262:Proceedings of the National Academy of Sciences 922:Proceedings of the National Academy of Sciences 1565: 1039: 1859:Members of the American Philosophical Society 1396:"The evolutionary origin of complex features" 1070: 1854:Fellows of the Ecological Society of America 1245: 1779:News release from Michigan State University 1175:. Michigan State University. Archived from 567:in 1996, and in 2006 he was elected to the 1599: 1071:Campbell, Neil A.; Reece, Jane B. (2005). 569:United States National Academy of Sciences 536:In 2021, Lenski was interviewed about the 36: 1358: 1348: 1299: 1281: 1127: 1008: 959: 941: 857: 800: 52:University of North Carolina, Chapel Hill 1603:The Longest-Running Evolution Experiment 392: 1784:The Loom : A New Step In Evolution 1791: 1754:List of publications at Google Scholar 1196: 1166: 1160: 1105:"Richard Lenski | Biographical Sketch" 880: 504:' book on the evidence for evolution, 389:E. coli long-term evolution experiment 66:E. coli long-term evolution experiment 1762:Long-term Experimental evolution site 1197:Lenski, Richard (February 15, 2023). 584:American Academy of Arts and Sciences 446:Richard Lenski has collaborated with 379: 1728:"Society for the Study of Evolution" 484:Conservapedia § Lenski dialogue 349:University of Massachusetts, Amherst 342: 1040:Richard Lenski (August 17, 2014). 699: 441: 13: 1641:"American Academy of Microbiology" 1566:Richard Lenski (August 19, 2013). 613:Society for the Study of Evolution 454:, and others on research using an 14: 1880: 1824:Michigan State University faculty 1747: 618: 312:Richard Lenski is the son of the 177:Bruce Levin (Postdoctoral Mentor) 1844:21st-century American biologists 1804:American evolutionary biologists 1568:"Welcome to Telliamed Revisited" 580:American Academy of Microbiology 353:University of California, Irvine 138:University of California, Irvine 1720: 1706: 1682: 1657: 1633: 1616: 1593: 1559: 1501: 1480: 1459: 1375: 1316: 1190: 1121: 1097: 1064: 371:, hosted by Isabelle Olivieri. 16:American evolutionary biologist 1864:Researchers of artificial life 1203:Journal of Molecular Evolution 1134:Journal of Theoretical Biology 1033: 976: 909: 874: 817: 752: 727: 713: 633:Journal of Theoretical Biology 606:American Philosophical Society 538:long-term evolution experiment 335:in 1976, and his PhD from the 1: 693: 307: 401:populations on June 25, 2008 337:University of North Carolina 262:National Academy of Sciences 174:Other academic advisors 7: 1169:"Source of founding strain" 1167:Lenski, Richard E. (2000). 842:10.1534/genetics.115.176677 374: 252:Distinguished Professor of 244:(born 1956) is an American 10: 1885: 1223:10.1007/s00239-023-10095-3 1173:Richard E. Lenski Homepage 883:International Microbiology 507:The Greatest Show on Earth 481: 386: 323:and the great-grandson of 18: 1849:Santa Fe Institute people 1600:Veritasium (2021-06-16). 739:Michigan State University 592:Michigan State University 550: 369:University of Montpellier 258:Michigan State University 203: 199: 181: 173: 161: 143: 134:Michigan State University 129: 113: 106: 71: 61: 47: 35: 28: 1869:American microbiologists 1732:www.evolutionsociety.org 462: 331:. He earned his AB from 260:. He is a member of the 1350:10.1073/pnas.0803151105 1283:10.1073/pnas.0803151105 1010:10.1126/science.aai8446 943:10.1073/pnas.0803151105 78:Friend of Darwin Award 1829:Oberlin College alumni 1146:10.1006/jtbi.1994.1146 604:He was elected to the 411:experimental evolution 402: 246:evolutionary biologist 121:Experimental evolution 557:Guggenheim Fellowship 555:Lenski was awarded a 430:that was able to use 396: 292:of novel traits, and 286:antibiotic resistance 98:Guggenheim Fellowship 1612:– via YouTube. 689:362: eaam5979.  565:MacArthur Fellowship 329:Richard C. H. Lenski 274:evolution experiment 118:Evolutionary biology 91:MacArthur Fellowship 21:Richard C. H. Lenski 1529:2001Natur.412..331W 1423:10.1038/nature01568 1415:2003Natur.423..139L 1341:2008PNAS..105.7899B 1274:2008PNAS..105.7899B 1215:2023JMolE..91..241L 1001:2016Sci...354.1301M 995:(6317): 1301–1304. 934:2008PNAS..105.7899B 785:10.1038/nature18959 777:2016Natur.536..165T 542:Derek Muller for a 469:Telliamed Revisited 282:clonal interference 84:Sewall Wright Award 1767:2017-07-27 at the 1628:Richard E. Lenski 1624:"Member directory" 1109:lenski.mmg.msu.edu 403: 221:telliamedrevisited 1814:MacArthur Fellows 1409:(6936): 139–144. 1335:(23): 7899–7906. 1090:978-0-8053-7146-8 928:(23): 7899–7906. 771:(7615): 165–170. 671:experiment.  656:population.  588:Microbial Ecology 361:Oxford University 343:Scientific career 300:organisms called 254:Microbial Ecology 242:Richard E. Lenski 239: 238: 194:Michael Travisano 182:Doctoral students 108:Scientific career 30:Richard E. Lenski 1876: 1742: 1741: 1739: 1738: 1724: 1718: 1717: 1710: 1704: 1703: 1701: 1700: 1686: 1680: 1679: 1677: 1676: 1661: 1655: 1654: 1652: 1651: 1637: 1631: 1620: 1614: 1613: 1611: 1610: 1597: 1591: 1578: 1572: 1571: 1563: 1557: 1556: 1537:10.1038/35085569 1514: 1505: 1499: 1498: 1496: 1495: 1484: 1478: 1477: 1475: 1474: 1463: 1457: 1456: 1454: 1453: 1447: 1441:. Archived from 1400: 1379: 1373: 1372: 1362: 1352: 1320: 1314: 1313: 1303: 1285: 1268:(23): 7899–906. 1256:Escherichia coli 1249: 1243: 1242: 1194: 1188: 1187: 1185: 1184: 1164: 1158: 1157: 1125: 1119: 1118: 1116: 1115: 1101: 1095: 1094: 1078: 1068: 1062: 1061: 1055: 1053: 1037: 1031: 1030: 1012: 980: 974: 973: 963: 945: 913: 907: 906: 878: 872: 871: 861: 821: 815: 814: 804: 756: 750: 749: 747: 746: 735:"Richard Lenski" 731: 725: 724: 717: 711: 710: 703: 654:Escherichia coli 442:Avida simulation 416:Escherichia coli 397:The 12 evolving 298:self-replicating 266:MacArthur Fellow 235: 232: 227: 224: 222: 217: 214: 212: 210: 163:Doctoral advisor 157: 102: 95: 88: 81: 40: 26: 25: 1884: 1883: 1879: 1878: 1877: 1875: 1874: 1873: 1789: 1788: 1769:Wayback Machine 1750: 1745: 1736: 1734: 1726: 1725: 1721: 1712: 1711: 1707: 1698: 1696: 1688: 1687: 1683: 1674: 1672: 1663: 1662: 1658: 1649: 1647: 1639: 1638: 1634: 1621: 1617: 1608: 1606: 1598: 1594: 1579: 1575: 1564: 1560: 1523:(6844): 331–3. 1512: 1506: 1502: 1493: 1491: 1486: 1485: 1481: 1472: 1470: 1465: 1464: 1460: 1451: 1449: 1445: 1398: 1382:Lenski, R. E.; 1380: 1376: 1321: 1317: 1250: 1246: 1195: 1191: 1182: 1180: 1165: 1161: 1126: 1122: 1113: 1111: 1103: 1102: 1098: 1091: 1069: 1065: 1051: 1049: 1038: 1034: 981: 977: 914: 910: 879: 875: 822: 818: 757: 753: 744: 742: 733: 732: 728: 719: 718: 714: 705: 704: 700: 696: 667:342: 1364-1367. 640:Ecology Letters 621: 553: 502:Richard Dawkins 486: 465: 456:artificial life 444: 391: 385: 377: 363:, working with 345: 333:Oberlin College 310: 229: 219: 207: 192: 188: 168:Nelson Hairston 155: 136: 100: 96: 93: 89: 86: 82: 79: 56:Oberlin College 54: 48:Alma mater 43: 31: 24: 17: 12: 11: 5: 1882: 1872: 1871: 1866: 1861: 1856: 1851: 1846: 1841: 1836: 1831: 1826: 1821: 1816: 1811: 1806: 1801: 1787: 1786: 1781: 1776: 1771: 1756: 1749: 1748:External links 1746: 1744: 1743: 1719: 1705: 1681: 1669:www.amacad.org 1656: 1632: 1615: 1592: 1573: 1558: 1500: 1479: 1458: 1388:Pennock, R. T. 1374: 1315: 1244: 1209:(1): 241–253. 1189: 1159: 1140:(3): 253–265. 1120: 1096: 1089: 1063: 1032: 975: 908: 889:(4): 265–270. 873: 836:(2): 619–631. 816: 751: 726: 712: 697: 695: 692: 691: 690: 683: 676: 675:536: 165-170. 668: 661: 650: 643: 636: 629: 628:91: 6808-6814. 620: 619:Selected works 617: 552: 549: 464: 461: 443: 440: 387:Main article: 384: 378: 376: 373: 344: 341: 317:Gerhard Lenski 309: 306: 278:mutation rates 250:John A. Hannah 237: 236: 205: 201: 200: 197: 196: 190:Zachary Blount 186:Paul E. 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Index

Richard C. H. Lenski

University of North Carolina, Chapel Hill
Oberlin College
E. coli long-term evolution experiment
NCSE
Sewall Wright Award
MacArthur Fellowship
Guggenheim Fellowship
Evolutionary biology
Experimental evolution
Microbiology
Michigan State University
University of California, Irvine
Thesis
Effects of competition and disturbance on ground beetle populations
Doctoral advisor
Nelson Hairston
Paul E. Turner
Zachary Blount
Michael Travisano
lenski.mmg.msu.edu
telliamedrevisited.wordpress.com
the-ltee.org
evolutionary biologist
John A. Hannah
Microbial Ecology
Michigan State University
National Academy of Sciences
MacArthur Fellow

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