365:
342:
264:
239:
3521:
3581:
3566:
3611:
623:
616:
3596:
3641:
371:
270:
3626:
3551:
3536:
40:
1944:. CCR5 is used by HIV as an entrance molecule to a cell. On the contrary, CCL5 in high concentration might increase HIV replication. The chemokine is involved also in antiviral response against other viruses. For instance, it has been shown that CCL5 is highly expressed in mice infected by
66:
2220:
1847:(GAGs) on the cell surface. For that, Glu66 and Glu26 are important. These amino acids are presented on the protein surface and allows ion interactions. In the experiment where these molecules were exchanged for serine, the self-aggregation did not occur.
1840:. Dimerization is not necessary for binding to CCR5. Thus, CCL5 in nanomolar concentration acts as classical chemokine and binds to its receptor. For the acting as classical chemokine and for the dimerization, N terminus of the molecule is important.
2860:"Diverging binding capacities of natural LD78beta isoforms of macrophage inflammatory protein-1alpha to the CC chemokine receptors 1, 3 and 5 affect their anti-HIV-1 activity and chemotactic potencies for neutrophils and eosinophils"
1783:
RANTES, along with the related chemokines MIP-1alpha and MIP-1beta, has been identified as a natural HIV-suppressive factor secreted by activated CD8+ T cells and other immune cells. The RANTES protein has been engineered for
1771:
transcription. The transcription factor is regulated by the JNK/MAPK pathway. Memory CD8+ T-cells are able to secrete CCL5 immediately after TCR stimulation, because they have a large number of preformed CCL5 mRNA in
378:
277:
1952:, virus-specific CD8+ T cells had reduced cytotoxic ability, reduced cytokines production and enhanced production of inhibitory molecules. It underscores the importance of CCL5 during chronic viral infection.
1755:. This is different from the most of other chemokines which are released almost immediately after cell stimulation. Thus, CCL5 is involved in inflammation maintaining. It also induces expression of
1940:-specific T-cell cytotoxicity. Moreover, it is considered that CCL5 in low concentration might inhibit HIV replication. It binds to CCR5 (as well as 2 other chemokines) on the surface of
3520:
2899:
Slimani H, Charnaux N, Mbemba E, Saffar L, Vassy R, Vita C, Gattegno L (October 2003). "Interaction of RANTES with syndecan-1 and syndecan-4 expressed by human primary macrophages".
2126:
Donlon TA, Krensky AM, Wallace MR, Collins FS, Lovett M, Clayberger C (March 1990). "Localization of a human T-cell-specific gene, RANTES (D17S136E), to chromosome 17q11.2-q12".
2221:"Hooked on HIV - What's the connection between a 1980s film character and the cutting edge of AIDS research? Philip Cohen reports on a protein that's unlocking HIV's mysteries"
1642:) that are released by T cells, CCL5 also induces the proliferation and activation of certain NK cells to form CHAK (CC-Chemokine-activated killer) cells. It is also an
3580:
3565:
4796:
1216:
1197:
200:
4185:
1549:
ecreted). RANTES was first described by Dr. Tom Schall who named the protein, the original source of the name Rantes was from the
Argentine movie
5824:
5431:
4257:
2108:
1885:. The apoptosis is dependent on GAGs binding on cell surface and there is a requirement of at least 4 CCL5 molecules to induce the apoptosis.
2090:
1739:
CCL5 was first identified in a search for genes expressed "late" (3–5 days) after T cell activation. It was subsequently determined to be a
5101:
3610:
3080:"Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants"
5471:
5466:
5456:
5451:
5446:
5426:
5371:
5366:
5356:
5341:
4789:
3595:
3437:"RANTES stimulates Ca2+ mobilization and inositol trisphosphate (IP3) formation in cells transfected with G protein-coupled receptor 75"
3031:"RANTES stimulates Ca2+ mobilization and inositol trisphosphate (IP3) formation in cells transfected with G protein-coupled receptor 75"
5673:
5512:
1428:
3267:
1435:
3315:
Muthumani K, Desai BM, Hwang DS, Choo AY, Laddy DJ, Thieu KP, et al. (April 2004). "HIV-1 Vpr and anti-inflammatory activity".
5653:
4261:
3640:
2876:
2859:
2280:
Maghazachi AA, Al-Aoukaty A, Schall TJ (February 1996). "CC chemokines induce the generation of killer cells from CD56+ cells".
5544:
4782:
4656:
1917:
5849:
3500:
2553:
2073:
1555:
about an alien who shows up in a mental ward who was named Rantés, the rather clunky acronym was only made to fit the name.
3625:
63:
3273:
2052:
1743:
and expressed in more than 100 human diseases. RANTES expression is regulated in T lymphocytes by
Kruppel like factor 13 (
3681:
2980:"Distribution of functional polymorphic variants of inflammation-related genes RANTES and CCR5 in long-lived individuals"
1945:
364:
4547:
2610:
Song A, Nikolcheva T, Krensky AM (October 2000). "Transcriptional regulation of RANTES expression in T lymphocytes".
2328:"Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells"
1857:
and they are not dependent on binding to the receptor. Activated T-cells (or other cells, for instance monocytes or
341:
1759:
which are important for migration of cells into the site of inflammation. CCL5 may be also expressed by NK cells.
5755:
5746:
4077:
2077:
2056:
2745:"Engineering of Lactobacillus jensenii to secrete RANTES and a CCR5 antagonist analogue as live HIV-1 blockers"
1912:
Importance of CCL5 is proved by various microbial strategies to avoid the activity of chemokine. For instance,
1265:
3550:
1652:
The chemokine CCL5 is mainly expressed by T-cells and monocytes, and it has not been shown to be expressed by
5668:
5549:
5236:
3854:
2704:"RANTES production by memory phenotype T cells is controlled by a posttranscriptional, TCR-dependent process"
263:
238:
1246:
1242:
180:
3529:: TOTAL CHEMICAL SYNTHESIS AND HIGH-RESOLUTION CRYSTAL STRUCTURE OF THE POTENT ANTI-HIV PROTEIN AOP-RANTES
3379:
Zhao RY, Bukrinsky M, Elder RT (April 2005). "HIV-1 viral protein R (Vpr) & host cellular responses".
4690:
4240:
4015:
3121:"CCL5-CCR5-mediated apoptosis in T cells: Requirement for glycosaminoglycan binding and CCL5 aggregation"
1803:
1794:
bacteria, and this solution is being developed into a possible HIV entry-inhibiting topical microbicide.
2571:"RFLAT-1: a new zinc finger transcription factor that activates RANTES gene expression in T lymphocytes"
4723:
4525:
4235:
1685:
377:
276:
2939:"The BBXB motif of RANTES is the principal site for heparin binding and controls receptor selectivity"
1843:
The second one occurs at high concentration of the chemokine. CCL5 creates self-aggregates binding to
4644:
4329:
3493:
1697:
370:
269:
167:
2496:
4679:
4106:
4082:
3214:"A role for the chemokine RANTES in regulating CD8 T cell responses during chronic viral infection"
1960:
1760:
1756:
1386:
1339:
188:
1902:
development and numerous human diseases and disorders, for instance viral hepatitis or COVID-19.
5312:
3674:
2786:
2003:
1712:
473. Then, the Akt/PKB complex phosphorylates and inactivates a serine/threonine protein kinase
1688:) family, it has the highest affinity to the CCR5. CCR5 is presented on the surface of T-cells,
1411:
1390:
1360:
1335:
4816:
4007:
2495:
Schall TJ, Jongstra J, Dyer BJ, Jorgensen J, Clayberger C, Davis MM, Krensky AM (August 1988).
1861:) either proliferate or perform apoptosis, and they release proinflammatory cytokines, such as
17:
3212:
Crawford A, Angelosanto JM, Nadwodny KL, Blackburn SD, Wherry EJ (July 2011). Douek DC (ed.).
2937:
Proudfoot AE, Fritchley S, Borlat F, Shaw JP, Vilbois F, Zwahlen C, et al. (April 2001).
1704:
and subsequently, the phosphorylated PI3K phosphorylates protein kinase B (PKB; also known as
2655:"JNK MAPK pathway regulates constitutive transcription of CCL5 by human NK cells through SP1"
2245:
Appay V, Rowland-Jones SL (January 2001). "RANTES: a versatile and controversial chemokine".
1913:
1895:
1777:
1506:
252:
5697:
4533:
3486:
2804:
Daugherty BL, Siciliano SJ, DeMartino JA, Malkowitz L, Sirotina A, Springer MS (May 1996).
2339:
1551:
208:
8:
4375:
3279:
3119:
Murooka TT, Wong MM, Rahbar R, Majchrzak-Kita B, Proudfoot AE, Fish EN (September 2006).
2858:
Struyf S, Menten P, Lenaerts JP, Put W, D'Haese A, De Clercq E, et al. (July 2001).
2007:
1619:
3589:: PROTON NMR ASSIGNMENTS AND SOLUTION CONFORMATION OF RANTES, A CHEMOKINE OF THE CC TYPE
3574:: PROTON NMR ASSIGNMENTS AND SOLUTION CONFORMATION OF RANTES, A CHEMOKINE OF THE CC TYPE
3535:
3402:"Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions"
2343:
5854:
4808:
4805:
4542:
4499:
4414:
4121:
3667:
3461:
3436:
3240:
3213:
3189:
3164:
3055:
3030:
2830:
2805:
2769:
2744:
2684:
2635:
2526:
2472:
2447:
2416:
2391:
2363:
2305:
2201:
1999:
212:
2720:
2703:
2587:
2570:
2258:
1131:
1126:
1121:
1116:
1111:
1106:
1101:
1096:
1091:
1086:
1081:
1076:
1071:
1066:
1061:
1056:
1051:
1046:
1041:
1036:
1031:
1026:
1021:
1016:
1011:
1006:
1001:
996:
991:
986:
981:
976:
971:
966:
961:
956:
951:
946:
941:
936:
931:
926:
921:
916:
911:
906:
901:
896:
891:
886:
881:
876:
871:
866:
861:
856:
851:
846:
841:
836:
831:
826:
821:
816:
811:
806:
801:
796:
791:
786:
770:
765:
760:
744:
739:
734:
729:
724:
719:
714:
709:
704:
699:
694:
689:
684:
679:
674:
669:
664:
171:, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP, C-C motif chemokine ligand 5
4406:
4025:
3891:
3466:
3423:
3388:
3367:
3332:
3295:
3286:
3245:
3194:
3142:
3101:
3060:
3011:
2960:
2916:
2881:
2835:
2774:
2725:
2676:
2627:
2623:
2592:
2549:
2518:
2477:
2421:
2355:
2297:
2262:
2205:
2153:
2139:
1991:
1972:
1844:
1837:
1693:
160:
56:
2806:"Cloning, expression, and characterization of the human eosinophil eotaxin receptor"
2639:
2530:
2367:
2309:
1696:
and other cell types. After the binding of CCL5 to CCR5, phosphoinositide 3-kinase (
4718:
4639:
4507:
4196:
4030:
3456:
3448:
3413:
3357:
3324:
3235:
3225:
3184:
3176:
3132:
3091:
3050:
3042:
3001:
2991:
2950:
2908:
2871:
2825:
2817:
2764:
2756:
2715:
2688:
2666:
2619:
2582:
2508:
2467:
2459:
2411:
2403:
2347:
2289:
2254:
2191:
2143:
2135:
1921:
1906:
1870:
1740:
1705:
1657:
1647:
1639:
1595:
457:
388:
332:
287:
2351:
192:
4245:
3931:
3230:
2912:
2407:
2326:
Cocchi F, DeVico AL, Garzino-Demo A, Arya SK, Gallo RC, Lusso P (December 1995).
2196:
2179:
2011:
1979:
1968:
1752:
1701:
432:
216:
4774:
2671:
2654:
2513:
2113:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2095:
National Center for
Biotechnology Information, U.S. National Library of Medicine
4759:
4754:
4609:
4605:
4587:
4582:
4385:
4380:
4370:
4365:
4360:
4355:
4350:
4346:
4315:
4310:
4305:
4284:
4279:
4274:
4269:
4224:
4219:
4214:
4209:
4157:
4142:
4133:
3690:
3328:
3165:"CCL5 as a potential immunotherapeutic target in triple-negative breast cancer"
2996:
2979:
1964:
1949:
1920:, which sequesters CCL5. The chemokine is released by virus-specific activated
1623:
533:
1832:
The first one occurs at low concentration of the chemokine. CCL5 may act as a
5843:
5436:
5346:
5024:
4749:
4744:
4739:
4685:
4634:
4300:
4204:
4180:
4175:
4152:
4147:
4138:
4129:
3911:
3096:
3079:
1956:
1941:
1866:
1862:
1790:
1768:
1689:
1635:
651:
3659:
2053:
ENSG00000274233 GRCh38: Ensembl release 89: ENSG00000271503, ENSG00000274233
1955:
Increased levels of CCL5 was discovered in lots of cancers. For instance in
593:
471:
5798:
5732:
5291:
5096:
4917:
4230:
4062:
3470:
3452:
3427:
3392:
3371:
3336:
3249:
3198:
3146:
3137:
3120:
3105:
3064:
3046:
3015:
2964:
2955:
2938:
2920:
2885:
2821:
2778:
2729:
2702:
Swanson BJ, Murakami M, Mitchell TC, Kappler J, Marrack P (November 2002).
2680:
2631:
2596:
2481:
2425:
2293:
2266:
1874:
1853:, the self-aggregates are strong activators of leukocytes. They can act as
1725:
1599:
622:
615:
450:
229:
3418:
3401:
3362:
3345:
2839:
2743:
Vangelista L, Secchi M, Liu X, Bachi A, Jia L, Xu Q, Lusso P (July 2010).
2522:
2359:
2301:
2157:
1716:. After the CCL5/CCR5 binding, some other proteins are regulated as well.
1475:
1470:
5766:
5663:
5579:
5564:
4927:
4651:
4597:
4338:
4097:
4020:
3006:
2760:
2148:
1807:
1673:
1310:
1291:
3180:
2546:
Biology of the
Chemokine in Rantes (Molecular Biology Intelligence Unit)
2463:
5683:
5643:
5569:
5111:
4704:
4397:
4087:
4047:
3078:
Appay V, Brown A, Cribbes S, Randle E, Czaplewski LG (September 1999).
2877:
10.1002/1521-4141(200107)31:7<2170::AID-IMMU2170>3.0.CO;2-D
2023:
1929:
1858:
1729:
1661:
1607:
1591:
1580:
1572:
1513:
349:
246:
196:
2653:
Kumar D, Hosse J, von Toerne C, Noessner E, Nelson PJ (January 2009).
2569:
Song A, Chen YF, Thamatrakoln K, Storm TA, Krensky AM (January 1999).
137:
133:
129:
125:
121:
117:
113:
109:
105:
101:
97:
93:
89:
85:
5554:
5522:
5106:
5091:
3709:
2448:"Mechanisms of disease: regulation of RANTES (CCL5) in renal disease"
2028:
1882:
1878:
1773:
1721:
1627:
1587:
1564:
1161:
416:
403:
315:
302:
204:
3211:
2803:
2327:
5819:
5297:
4699:
3694:
3435:
Ignatov A, Robert J, Gregory-Evans C, Schaller HC (November 2006).
3029:
Ignatov A, Robert J, Gregory-Evans C, Schaller HC (November 2006).
2497:"A human T cell-specific molecule is a member of a new gene family"
1983:
1925:
1849:
1733:
1665:
1631:
1615:
1611:
1583:
1568:
1459:
1072:
negative regulation of G protein-coupled receptor signaling pathway
3434:
3028:
1828:
CCL5 has two mechanisms of action according to its concentration.
5121:
3300:
3290:
1978:
CCL5 plays an important role in various human disorders, such as
1854:
1833:
1576:
1495:
1277:
1228:
1146:
1142:
1751:
gene is activated after 3–5 days after activation of T-cell via
184:
5808:
5658:
5648:
5622:
5601:
5507:
5502:
4577:
4474:
4469:
4464:
4459:
4454:
4449:
4167:
3972:
3956:
3951:
3946:
3941:
3936:
3926:
3921:
3118:
1995:
1709:
1684:, belonging to seven transmembrane G-protein coupled receptor (
1653:
1603:
1536:
1443:
1183:
942:
positive regulation of tyrosine phosphorylation of STAT protein
631:
39:
3619:: human RANTES complexed to heparin-derived disaccharide III-S
3478:
2787:"Microbicide containing engineered bacteria may inhibit HIV-1"
2701:
1067:
positive regulation of phosphatidylinositol 3-kinase signaling
987:
positive regulation of receptor signaling pathway via JAK-STAT
792:
positive regulation of cell-cell adhesion mediated by integrin
5787:
5632:
5611:
5590:
5533:
5497:
5492:
5481:
5421:
5416:
5411:
5406:
5401:
5396:
5381:
5336:
5321:
5272:
5267:
5262:
5251:
5241:
5225:
5215:
5194:
5168:
5163:
5142:
5081:
5076:
5071:
5066:
5014:
5009:
4978:
4973:
4968:
4963:
4958:
4953:
4948:
4907:
4902:
4871:
4866:
4861:
4856:
4613:
4572:
4567:
4562:
4557:
4552:
4489:
4479:
4444:
4439:
4434:
4429:
4424:
4419:
4072:
4067:
4057:
4042:
4037:
3916:
3906:
3901:
3896:
3886:
3881:
3875:
3859:
3849:
3844:
3839:
3834:
3829:
3824:
3819:
3814:
3808:
3803:
3798:
3793:
3788:
3783:
3778:
3773:
1899:
1822:
1744:
1717:
1713:
670:
receptor signaling protein tyrosine kinase activator activity
3604:: human RANTES complexed to heparin-derived disaccharide I-S
3285:
Overview of all the structural information available in the
2936:
2652:
2325:
1728:
is phosphorylated and degraded. An important protein in the
5722:
5717:
5706:
5204:
5189:
5178:
5152:
5131:
5061:
5051:
5046:
5035:
4999:
4988:
4943:
4897:
4892:
4881:
4851:
4846:
4836:
4825:
4537:
4484:
4052:
3993:
3988:
3768:
3763:
3758:
3753:
3741:
3735:
3729:
3724:
2898:
2494:
2125:
1987:
1933:
1815:
1811:
1681:
1677:
1669:
1502:
1087:
negative regulation of chemokine-mediated signaling pathway
2279:
1112:
positive regulation of activation of Janus kinase activity
2568:
2392:"CCL5/CCR5 axis in human diseases and related treatments"
1937:
1932:. In cytotoxic T-cells (CTL) killing other cells via Fas/
1873:. CCL5 mediated apoptosis in T-cells includes release of
1643:
2742:
440:
3314:
3077:
2857:
1905:
For instance, CCL5 level is higher during rejection of
1102:
positive regulation of protein tyrosine kinase activity
1007:
positive regulation of smooth muscle cell proliferation
882:
cellular response to fibroblast growth factor stimulus
3649:: Crystal Structure of human RANTES mutant 44-AANA-47
2609:
1027:
positive regulation of natural killer cell chemotaxis
605:
3400:
Li L, Li HS, Pauza CD, Bukrinsky M, Zhao RY (2006).
2178:
Chen L, Zhang Q, Yu C, Wang F, Kong X (2020-03-01).
937:
positive regulation of epithelial cell proliferation
867:
positive regulation of cellular biosynthetic process
2785:American Society for Microbiology (July 24, 2010).
1916:(HCMV) express a viral chemokine receptor analogue
1821:CCL5 also activates the G-protein coupled receptor
967:
positive regulation of homotypic cell-cell adhesion
907:
negative regulation of macrophage apoptotic process
802:
positive regulation of smooth muscle cell migration
3399:
3378:
3163:Lv D, Zhang Y, Kim HJ, Zhang L, Ma X (July 2013).
2901:Biochimica et Biophysica Acta (BBA) - Biomembranes
2244:
2180:"Functional roles of CCL5/RANTES in liver disease"
2069:
2067:
2065:
2048:
2046:
2044:
4804:
3346:"Viral infections and cell cycle G2/M regulation"
2537:
387:
286:
5841:
1594:. CCL5 is proinflammatory chemokine, recruiting
3634:: Crystal Structure of human RANTES mutant K45E
3162:
2932:
2930:
2853:
2851:
2849:
2543:
2177:
2062:
2041:
1077:positive regulation of T cell apoptotic process
982:positive regulation of viral genome replication
927:positive regulation of translational initiation
897:negative regulation of T cell apoptotic process
812:negative regulation of viral genome replication
2321:
2319:
2074:GRCm38: Ensembl release 89: ENSMUSG00000035042
4790:
3689:
3675:
3494:
2971:
2389:
992:lipopolysaccharide-mediated signaling pathway
822:positive regulation of innate immune response
690:phosphatidylinositol phospholipase C activity
3022:
2977:
2927:
2892:
2846:
2736:
2603:
2562:
2390:Zeng Z, Lan T, Wei Y, Wei X (January 2022).
1122:G protein-coupled receptor signaling pathway
947:cellular response to organic cyclic compound
847:positive regulation of calcium ion transport
832:positive regulation of macrophage chemotaxis
817:positive regulation of ERK1 and ERK2 cascade
2797:
2488:
2316:
1002:regulation of chronic inflammatory response
912:positive regulation of T cell proliferation
4797:
4783:
3682:
3668:
3501:
3487:
2445:
2273:
2119:
1656:. Moreover, it is abundantly expressed by
1505:. The gene has been discovered in 1990 by
1107:cellular response to tumor necrosis factor
877:positive regulation of monocyte chemotaxis
3460:
3417:
3361:
3343:
3239:
3229:
3188:
3136:
3095:
3054:
3005:
2995:
2954:
2875:
2829:
2768:
2719:
2670:
2586:
2512:
2471:
2415:
2195:
2147:
1117:regulation of signaling receptor activity
1889:
1057:positive regulation of T cell chemotaxis
1776:and its secretion is dependent only on
997:positive regulation of T cell migration
14:
5842:
3381:The Indian Journal of Medical Research
917:positive regulation of phosphorylation
902:positive regulation of GTPase activity
807:activation of phospholipase D activity
725:chemokine receptor antagonist activity
5754:
4778:
3663:
3482:
3158:
3156:
2749:Antimicrobial Agents and Chemotherapy
2441:
2439:
2437:
2435:
2385:
2383:
2381:
2379:
2377:
2218:
1736:, is inhibited by inactivated GSK-3.
1022:positive regulation of cell migration
827:cellular response to interferon-gamma
392:
353:
348:
291:
250:
245:
2810:The Journal of Experimental Medicine
2452:Nature Clinical Practice. Nephrology
2240:
2238:
2236:
2234:
2232:
2230:
2173:
2171:
2169:
2167:
1668:. Although it can bind to receptors
1563:CCL5 belongs to the CC subfamily of
1082:positive regulation of cell adhesion
862:chemokine-mediated signaling pathway
5705:
3169:Cellular & Molecular Immunology
3125:The Journal of Biological Chemistry
3084:The Journal of Biological Chemistry
2943:The Journal of Biological Chemistry
1877:in cytoplasm and the activation of
1767:gene and mediates its constitutive
1512:and it is localised on 17q11.2-q12
1127:cytokine-mediated signaling pathway
24:
3559:: HUMAN RANTES, NMR, 13 STRUCTURES
3307:
3153:
2432:
2374:
1946:lymphocytic choriomeningitis virus
1646:-suppressive factor released from
1498:which in humans is encoded by the
972:cellular response to interleukin-1
25:
5866:
3260:
2978:Laplana M, Fibla J (April 2012).
2446:Krensky AM, Ahn YT (March 2007).
2227:
2164:
1720:is more expressed and it induces
892:response to tumor necrosis factor
720:protein homodimerization activity
27:Mammalian protein found in humans
3639:
3624:
3609:
3594:
3579:
3564:
3549:
3534:
3519:
3344:Zhao RY, Elder RT (March 2005).
2624:10.1034/j.1600-065X.2000.17610.x
952:cellular calcium ion homeostasis
710:phospholipase activator activity
621:
614:
376:
369:
363:
340:
275:
268:
262:
237:
38:
5097:Cenicriviroc (TAK-652, TBR-652)
4918:Cenicriviroc (TAK-652, TBR-652)
3508:
3441:British Journal of Pharmacology
3299:(C-C motif chemokine 5) at the
3205:
3112:
3071:
3035:British Journal of Pharmacology
2695:
2646:
1797:
1690:smooth muscle endothelial cells
857:regulation of insulin secretion
797:regulation of T cell activation
705:CCR1 chemokine receptor binding
685:CCR4 chemokine receptor binding
665:CCR5 chemokine receptor binding
2864:European Journal of Immunology
2282:European Journal of Immunology
2223:. Copyright New Scientist Ltd.
2212:
2101:
2083:
1630:. With the help of particular
1488:Chemokine (C-C motif) ligand 5
745:CCR chemokine receptor binding
632:More reference expression data
594:More reference expression data
13:
1:
2721:10.1016/S1074-7613(02)00456-9
2588:10.1016/S1074-7613(00)80010-2
2352:10.1126/science.270.5243.1811
2259:10.1016/S1471-4906(00)01812-3
2034:
361:
260:
5850:Genes on human chromosome 17
5437:Interleukin-8 (CXCL8, GCP-1)
5347:Interleukin-8 (CXCL8, GCP-1)
3231:10.1371/journal.ppat.1002098
2913:10.1016/j.bbamem.2003.09.006
2408:10.1016/j.gendis.2021.08.004
2219:Cohen P (14 December 1996).
2197:10.1016/j.livres.2020.01.002
2140:10.1016/0888-7543(90)90485-D
1936:interaction, CCL5 increases
787:leukocyte cell-cell adhesion
7:
2672:10.4049/jimmunol.182.2.1011
2514:10.4049/jimmunol.141.3.1018
2017:
1558:
932:response to toxic substance
572:subcutaneous adipose tissue
10:
5871:
3329:10.1089/104454904773819824
3278:gene details page in the
2997:10.1016/j.cyto.2011.12.021
1062:regulation of neuron death
1017:protein kinase B signaling
715:chemokine receptor binding
552:superior surface of tongue
5807:
5786:
5779:
5745:
5696:
5631:
5610:
5589:
5532:
5480:
5380:
5320:
5311:
5281:
5250:
5224:
5203:
5177:
5151:
5130:
5034:
4987:
4926:
4880:
4824:
4815:
4669:
4645:Colony-stimulating factor
4627:
4596:
4524:
4498:
4405:
4396:
4337:
4328:
4293:
4256:
4194:
4166:
4120:
4105:
4096:
4006:
3981:
3965:
3868:
3717:
3708:
3701:
3514:
2109:"Mouse PubMed Reference:"
2091:"Human PubMed Reference:"
1757:matrix metalloproteinases
1620:natural-killer (NK) cells
1474:
1469:
1465:
1458:
1442:
1423:
1408:
1404:
1383:
1379:
1372:
1357:
1353:
1332:
1328:
1321:
1308:
1304:
1289:
1285:
1276:
1263:
1259:
1240:
1236:
1227:
1214:
1210:
1195:
1191:
1182:
1167:
1160:
1156:
1140:
1042:dendritic cell chemotaxis
740:identical protein binding
650:
646:
629:
613:
604:
591:
540:
531:
478:
469:
439:
431:
427:
410:
397:
360:
339:
330:
326:
309:
296:
259:
236:
227:
223:
178:
175:
165:
158:
153:
82:
77:
60:
55:
50:
46:
37:
32:
4680:proinflammatory cytokine
3097:10.1074/jbc.274.39.27505
2544:Alan M. Krensky (1995).
1961:hepatocellular carcinoma
1761:SP1 transcription factor
1602:. It is chemotactic for
1436:Chr 11: 83.42 – 83.42 Mb
1429:Chr 17: 35.87 – 35.88 Mb
735:chemoattractant activity
680:protein self-association
1898:, anti-viral immunity,
1802:CCL5 has been shown to
957:protein tetramerization
695:protein kinase activity
5472:Reparixin (repertaxin)
5372:Reparixin (repertaxin)
3811:/PARC/DCCK1/AMAC1/MIP4
3453:10.1038/sj.bjp.0706909
3138:10.1074/jbc.M603912200
3047:10.1038/sj.bjp.0706909
2956:10.1074/jbc.M010867200
2822:10.1084/jem.183.5.2349
2294:10.1002/eji.1830260207
1579:acting as a classical
1567:, due to its adjacent
544:mesenteric lymph nodes
5723:Lymphotactin-β (XCL2)
5718:Lymphotactin-α (XCL1)
3419:10.1038/sj.cr.7290370
3363:10.1038/sj.cr.7290279
2659:Journal of Immunology
2612:Immunological Reviews
2501:Journal of Immunology
2004:alcohol liver disease
1914:human cytomegalovirus
1890:Clinical significance
1132:lymphocyte chemotaxis
1052:macrophage chemotaxis
1037:eosinophil chemotaxis
1012:neutrophil activation
922:inflammatory response
887:neutrophil chemotaxis
837:calcium ion transport
394:11 C|11 50.66 cM
355:Chromosome 11 (mouse)
253:Chromosome 17 (human)
5767:Fractalkine (CX3CL1)
5684:Plerixafor (AMD3100)
5570:Plerixafor (AMD3100)
3317:DNA and Cell Biology
3272:genome location and
2761:10.1128/AAC.01492-09
2396:Genes & Diseases
2247:Trends in Immunology
1894:CCL5 is involved in
1692:, epithelial cells,
1590:. It consists of 68
1552:Man Facing Southeast
1519:It is also known as
852:response to cytokine
766:extracellular region
78:List of PDB id codes
51:Available structures
4376:Interferon type III
3280:UCSC Genome Browser
3181:10.1038/cmi.2012.69
3131:(35): 25184–25194.
3090:(39): 27505–27512.
2949:(14): 10620–10626.
2464:10.1038/ncpneph0418
2344:1995Sci...270.1811C
2338:(5243): 1811–1815.
2008:acute liver failure
1097:positive chemotaxis
1092:monocyte chemotaxis
1032:cell-cell signaling
771:extracellular space
510:epithelium of colon
4806:Chemokine receptor
3412:(11–12): 923–934.
2000:glomerulonephritis
1845:glycosaminoglycans
1266:ENSMUSG00000035042
780:Biological process
754:Cellular component
675:chemokine activity
658:Molecular function
5837:
5836:
5833:
5832:
5799:CC (β) chemokines
5775:
5774:
5741:
5740:
5692:
5691:
5386:
5326:
5307:
5306:
4772:
4771:
4665:
4664:
4623:
4622:
4520:
4519:
4516:
4515:
4324:
4323:
4002:
4001:
3657:
3656:
2783:*Lay summary in:
2555:978-1-57059-253-9
2548:. R G Landes Co.
1992:atopic dermatitis
1973:pancreatic cancer
1694:parenchymal cells
1485:
1484:
1481:
1480:
1454:
1453:
1419:
1418:
1398:
1397:
1368:
1367:
1347:
1346:
1317:
1316:
1298:
1297:
1272:
1271:
1253:
1252:
1223:
1222:
1204:
1203:
1152:
1151:
872:response to virus
700:cytokine activity
642:
641:
638:
637:
600:
599:
587:
586:
525:
524:
423:
422:
322:
321:
149:
148:
145:
144:
61:Ortholog search:
16:(Redirected from
5862:
5784:
5783:
5752:
5751:
5703:
5702:
5525:(against CXCL10)
5384:
5324:
5318:
5317:
4822:
4821:
4799:
4792:
4785:
4776:
4775:
4403:
4402:
4335:
4334:
4118:
4117:
4103:
4102:
3715:
3714:
3706:
3705:
3684:
3677:
3670:
3661:
3660:
3643:
3628:
3613:
3598:
3583:
3568:
3553:
3538:
3523:
3503:
3496:
3489:
3480:
3479:
3474:
3464:
3431:
3421:
3396:
3375:
3365:
3340:
3254:
3253:
3243:
3233:
3209:
3203:
3202:
3192:
3160:
3151:
3150:
3140:
3116:
3110:
3109:
3099:
3075:
3069:
3068:
3058:
3026:
3020:
3019:
3009:
2999:
2975:
2969:
2968:
2958:
2934:
2925:
2924:
2896:
2890:
2889:
2879:
2870:(7): 2170–2178.
2855:
2844:
2843:
2833:
2816:(5): 2349–2354.
2801:
2795:
2794:
2782:
2772:
2755:(7): 2994–3001.
2740:
2734:
2733:
2723:
2699:
2693:
2692:
2674:
2665:(2): 1011–1020.
2650:
2644:
2643:
2607:
2601:
2600:
2590:
2566:
2560:
2559:
2541:
2535:
2534:
2516:
2507:(3): 1018–1025.
2492:
2486:
2485:
2475:
2443:
2430:
2429:
2419:
2387:
2372:
2371:
2323:
2314:
2313:
2277:
2271:
2270:
2242:
2225:
2224:
2216:
2210:
2209:
2199:
2175:
2162:
2161:
2151:
2123:
2117:
2116:
2105:
2099:
2098:
2087:
2081:
2071:
2060:
2050:
1907:renal transplant
1896:transplantations
1658:epithelial cells
1575:. It is an 8kDa
1467:
1466:
1438:
1431:
1414:
1402:
1401:
1393:
1377:
1376:
1373:RefSeq (protein)
1363:
1351:
1350:
1342:
1326:
1325:
1302:
1301:
1283:
1282:
1257:
1256:
1234:
1233:
1208:
1207:
1189:
1188:
1158:
1157:
648:
647:
634:
625:
618:
611:
610:
596:
536:
534:Top expressed in
529:
528:
474:
472:Top expressed in
467:
466:
446:
445:
429:
428:
419:
406:
395:
380:
373:
367:
356:
344:
328:
327:
318:
305:
294:
279:
272:
266:
255:
241:
225:
224:
219:
217:CCL5 - orthologs
170:
163:
140:
75:
74:
69:
48:
47:
42:
30:
29:
21:
5870:
5869:
5865:
5864:
5863:
5861:
5860:
5859:
5840:
5839:
5838:
5829:
5803:
5771:
5737:
5688:
5627:
5606:
5585:
5582:(against CXCR4)
5528:
5476:
5383:
5376:
5323:
5303:
5294:(against CCL11)
5277:
5246:
5220:
5199:
5173:
5147:
5126:
5030:
4983:
4922:
4876:
4811:
4803:
4773:
4768:
4734:
4713:
4671:
4661:
4619:
4592:
4512:
4494:
4392:
4320:
4289:
4252:
4190:
4162:
4113:
4111:
4109:
4092:
3998:
3977:
3961:
3864:
3697:
3688:
3658:
3653:
3650:
3644:
3635:
3629:
3620:
3614:
3605:
3599:
3590:
3584:
3575:
3569:
3560:
3554:
3545:
3539:
3530:
3524:
3510:
3507:
3477:
3310:
3308:Further reading
3263:
3258:
3257:
3224:(7): e1002098.
3210:
3206:
3161:
3154:
3117:
3113:
3076:
3072:
3027:
3023:
2976:
2972:
2935:
2928:
2897:
2893:
2856:
2847:
2802:
2798:
2784:
2741:
2737:
2700:
2696:
2651:
2647:
2608:
2604:
2567:
2563:
2556:
2542:
2538:
2493:
2489:
2444:
2433:
2388:
2375:
2324:
2317:
2278:
2274:
2243:
2228:
2217:
2213:
2176:
2165:
2124:
2120:
2107:
2106:
2102:
2089:
2088:
2084:
2072:
2063:
2051:
2042:
2037:
2020:
2012:viral hepatitis
1980:atherosclerosis
1969:prostate cancer
1892:
1800:
1624:dendritic cells
1614:, but also for
1598:to the site of
1561:
1476:View/Edit Mouse
1471:View/Edit Human
1434:
1427:
1424:Location (UCSC)
1410:
1389:
1385:
1359:
1338:
1334:
1247:ENSG00000274233
1245:
1243:ENSG00000271503
1136:
977:immune response
775:
749:
730:protein binding
630:
620:
619:
592:
583:
578:
574:
570:
566:
562:
558:
554:
550:
546:
532:
521:
516:
512:
508:
504:
500:
496:
492:
488:
484:
470:
414:
401:
393:
383:
382:
381:
374:
354:
331:Gene location (
313:
300:
292:
282:
281:
280:
273:
251:
228:Gene location (
179:
166:
159:
84:
62:
28:
23:
22:
15:
12:
11:
5:
5868:
5858:
5857:
5852:
5835:
5834:
5831:
5830:
5828:
5827:
5822:
5813:
5811:
5805:
5804:
5802:
5801:
5792:
5790:
5781:
5777:
5776:
5773:
5772:
5770:
5769:
5760:
5758:
5749:
5743:
5742:
5739:
5738:
5736:
5735:
5726:
5725:
5720:
5711:
5709:
5700:
5694:
5693:
5690:
5689:
5687:
5686:
5677:
5676:
5671:
5669:SDF-1 (CXCL12)
5666:
5661:
5656:
5651:
5649:CXCL11 (I-TAC)
5646:
5637:
5635:
5629:
5628:
5626:
5625:
5616:
5614:
5608:
5607:
5605:
5604:
5595:
5593:
5587:
5586:
5584:
5583:
5573:
5572:
5567:
5558:
5557:
5552:
5550:SDF-1 (CXCL12)
5547:
5538:
5536:
5530:
5529:
5527:
5526:
5516:
5515:
5510:
5508:CXCL11 (I-TAC)
5505:
5503:CXCL10 (IP-10)
5500:
5495:
5486:
5484:
5478:
5477:
5475:
5474:
5469:
5460:
5459:
5454:
5449:
5440:
5439:
5434:
5429:
5424:
5419:
5414:
5409:
5404:
5399:
5390:
5388:
5378:
5377:
5375:
5374:
5369:
5360:
5359:
5350:
5349:
5344:
5339:
5330:
5328:
5315:
5309:
5308:
5305:
5304:
5302:
5301:
5300:(against CCL2)
5295:
5285:
5283:
5279:
5278:
5276:
5275:
5270:
5265:
5256:
5254:
5248:
5247:
5245:
5244:
5239:
5230:
5228:
5222:
5221:
5219:
5218:
5209:
5207:
5201:
5200:
5198:
5197:
5192:
5183:
5181:
5175:
5174:
5172:
5171:
5166:
5157:
5155:
5149:
5148:
5146:
5145:
5136:
5134:
5128:
5127:
5125:
5124:
5115:
5114:
5109:
5104:
5099:
5094:
5085:
5084:
5079:
5074:
5069:
5064:
5059:
5054:
5049:
5040:
5038:
5032:
5031:
5029:
5028:
5027:(against CCR4)
5018:
5017:
5012:
5007:
5002:
4993:
4991:
4985:
4984:
4982:
4981:
4976:
4971:
4966:
4961:
4956:
4951:
4946:
4941:
4932:
4930:
4924:
4923:
4921:
4920:
4911:
4910:
4905:
4900:
4895:
4886:
4884:
4878:
4877:
4875:
4874:
4869:
4864:
4859:
4854:
4849:
4844:
4839:
4830:
4828:
4819:
4813:
4812:
4802:
4801:
4794:
4787:
4779:
4770:
4769:
4767:
4766:
4765:
4764:
4763:
4762:
4757:
4752:
4747:
4742:
4732:
4728:
4727:
4726:
4721:
4711:
4702:
4696:
4695:
4694:
4693:
4688:
4675:
4673:
4667:
4666:
4663:
4662:
4660:
4659:
4654:
4649:
4648:
4647:
4642:
4631:
4629:
4625:
4624:
4621:
4620:
4618:
4617:
4602:
4600:
4594:
4593:
4591:
4590:
4585:
4580:
4575:
4570:
4565:
4560:
4555:
4550:
4545:
4540:
4530:
4528:
4526:Ig superfamily
4522:
4521:
4518:
4517:
4514:
4513:
4511:
4510:
4504:
4502:
4496:
4495:
4493:
4492:
4487:
4482:
4477:
4472:
4467:
4462:
4457:
4452:
4447:
4442:
4437:
4432:
4427:
4422:
4417:
4411:
4409:
4400:
4394:
4393:
4391:
4390:
4389:
4388:
4383:
4373:
4368:
4363:
4358:
4353:
4343:
4341:
4332:
4326:
4325:
4322:
4321:
4319:
4318:
4313:
4308:
4303:
4297:
4295:
4291:
4290:
4288:
4287:
4282:
4277:
4272:
4266:
4264:
4254:
4253:
4251:
4250:
4249:
4248:
4243:
4238:
4233:
4222:
4217:
4212:
4207:
4201:
4199:
4192:
4191:
4189:
4188:
4183:
4178:
4172:
4170:
4164:
4163:
4161:
4160:
4155:
4150:
4145:
4136:
4126:
4124:
4115:
4100:
4094:
4093:
4091:
4090:
4085:
4080:
4075:
4070:
4065:
4060:
4055:
4050:
4045:
4040:
4035:
4034:
4033:
4028:
4018:
4012:
4010:
4004:
4003:
4000:
3999:
3997:
3996:
3991:
3985:
3983:
3979:
3978:
3976:
3975:
3969:
3967:
3963:
3962:
3960:
3959:
3954:
3949:
3944:
3939:
3934:
3929:
3924:
3919:
3914:
3909:
3904:
3899:
3894:
3889:
3884:
3879:
3872:
3870:
3866:
3865:
3863:
3862:
3857:
3852:
3847:
3842:
3837:
3832:
3827:
3822:
3817:
3812:
3806:
3801:
3796:
3791:
3786:
3781:
3776:
3771:
3766:
3761:
3756:
3751:
3745:
3739:
3733:
3727:
3721:
3719:
3712:
3703:
3699:
3698:
3691:Cell signaling
3687:
3686:
3679:
3672:
3664:
3655:
3654:
3652:
3651:
3645:
3638:
3636:
3630:
3623:
3621:
3615:
3608:
3606:
3600:
3593:
3591:
3585:
3578:
3576:
3570:
3563:
3561:
3555:
3548:
3546:
3540:
3533:
3531:
3525:
3518:
3515:
3512:
3511:
3506:
3505:
3498:
3491:
3483:
3476:
3475:
3447:(5): 490–497.
3432:
3397:
3387:(4): 270–286.
3376:
3356:(3): 143–149.
3341:
3323:(4): 239–247.
3311:
3309:
3306:
3305:
3304:
3283:
3262:
3261:External links
3259:
3256:
3255:
3218:PLOS Pathogens
3204:
3175:(4): 303–310.
3152:
3111:
3070:
3041:(5): 490–497.
3021:
2970:
2926:
2907:(1–2): 80–88.
2891:
2845:
2796:
2735:
2714:(5): 605–615.
2694:
2645:
2602:
2561:
2554:
2536:
2487:
2458:(3): 164–170.
2431:
2373:
2315:
2288:(2): 315–319.
2272:
2226:
2211:
2184:Liver Research
2163:
2134:(3): 548–553.
2118:
2100:
2082:
2061:
2039:
2038:
2036:
2033:
2032:
2031:
2026:
2019:
2016:
1965:stomach cancer
1950:knock-out mice
1924:together with
1891:
1888:
1887:
1886:
1841:
1799:
1796:
1788:production by
1763:binds near to
1702:phosphorylated
1560:
1557:
1483:
1482:
1479:
1478:
1473:
1463:
1462:
1456:
1455:
1452:
1451:
1449:
1447:
1440:
1439:
1432:
1425:
1421:
1420:
1417:
1416:
1406:
1405:
1399:
1396:
1395:
1381:
1380:
1374:
1370:
1369:
1366:
1365:
1355:
1354:
1348:
1345:
1344:
1330:
1329:
1323:
1319:
1318:
1315:
1314:
1306:
1305:
1299:
1296:
1295:
1287:
1286:
1280:
1274:
1273:
1270:
1269:
1261:
1260:
1254:
1251:
1250:
1238:
1237:
1231:
1225:
1224:
1221:
1220:
1212:
1211:
1205:
1202:
1201:
1193:
1192:
1186:
1180:
1179:
1174:
1169:
1165:
1164:
1154:
1153:
1150:
1149:
1138:
1137:
1135:
1134:
1129:
1124:
1119:
1114:
1109:
1104:
1099:
1094:
1089:
1084:
1079:
1074:
1069:
1064:
1059:
1054:
1049:
1044:
1039:
1034:
1029:
1024:
1019:
1014:
1009:
1004:
999:
994:
989:
984:
979:
974:
969:
964:
959:
954:
949:
944:
939:
934:
929:
924:
919:
914:
909:
904:
899:
894:
889:
884:
879:
874:
869:
864:
859:
854:
849:
844:
839:
834:
829:
824:
819:
814:
809:
804:
799:
794:
789:
783:
781:
777:
776:
774:
773:
768:
763:
757:
755:
751:
750:
748:
747:
742:
737:
732:
727:
722:
717:
712:
707:
702:
697:
692:
687:
682:
677:
672:
667:
661:
659:
655:
654:
644:
643:
640:
639:
636:
635:
627:
626:
608:
602:
601:
598:
597:
589:
588:
585:
584:
582:
581:
577:
573:
569:
565:
561:
557:
553:
549:
545:
541:
538:
537:
526:
523:
522:
520:
519:
515:
511:
507:
503:
499:
495:
491:
487:
483:
479:
476:
475:
463:
462:
454:
443:
437:
436:
433:RNA expression
425:
424:
421:
420:
412:
408:
407:
399:
396:
391:
385:
384:
375:
368:
362:
358:
357:
352:
346:
345:
337:
336:
324:
323:
320:
319:
311:
307:
306:
298:
295:
290:
284:
283:
274:
267:
261:
257:
256:
249:
243:
242:
234:
233:
221:
220:
177:
173:
172:
164:
156:
155:
151:
150:
147:
146:
143:
142:
80:
79:
71:
70:
59:
53:
52:
44:
43:
35:
34:
26:
9:
6:
4:
3:
2:
5867:
5856:
5853:
5851:
5848:
5847:
5845:
5826:
5823:
5821:
5818:
5815:
5814:
5812:
5810:
5806:
5800:
5797:
5794:
5793:
5791:
5789:
5785:
5782:
5778:
5768:
5765:
5762:
5761:
5759:
5757:
5753:
5750:
5748:
5744:
5734:
5731:
5728:
5727:
5724:
5721:
5719:
5716:
5713:
5712:
5710:
5708:
5704:
5701:
5699:
5695:
5685:
5682:
5679:
5678:
5675:
5672:
5670:
5667:
5665:
5662:
5660:
5657:
5655:
5652:
5650:
5647:
5645:
5642:
5639:
5638:
5636:
5634:
5630:
5624:
5621:
5618:
5617:
5615:
5613:
5609:
5603:
5600:
5597:
5596:
5594:
5592:
5588:
5581:
5578:
5575:
5574:
5571:
5568:
5566:
5563:
5560:
5559:
5556:
5553:
5551:
5548:
5546:
5543:
5540:
5539:
5537:
5535:
5531:
5524:
5521:
5518:
5517:
5514:
5511:
5509:
5506:
5504:
5501:
5499:
5496:
5494:
5491:
5488:
5487:
5485:
5483:
5479:
5473:
5470:
5468:
5465:
5462:
5461:
5458:
5455:
5453:
5450:
5448:
5445:
5442:
5441:
5438:
5435:
5433:
5430:
5428:
5425:
5423:
5420:
5418:
5415:
5413:
5410:
5408:
5405:
5403:
5400:
5398:
5395:
5392:
5391:
5389:
5387:
5379:
5373:
5370:
5368:
5365:
5362:
5361:
5358:
5355:
5352:
5351:
5348:
5345:
5343:
5340:
5338:
5335:
5332:
5331:
5329:
5327:
5319:
5316:
5314:
5310:
5299:
5296:
5293:
5290:
5287:
5286:
5284:
5280:
5274:
5271:
5269:
5266:
5264:
5261:
5258:
5257:
5255:
5253:
5249:
5243:
5240:
5238:
5235:
5232:
5231:
5229:
5227:
5223:
5217:
5214:
5211:
5210:
5208:
5206:
5202:
5196:
5193:
5191:
5188:
5185:
5184:
5182:
5180:
5176:
5170:
5167:
5165:
5162:
5159:
5158:
5156:
5154:
5150:
5144:
5141:
5138:
5137:
5135:
5133:
5129:
5123:
5120:
5117:
5116:
5113:
5110:
5108:
5105:
5103:
5100:
5098:
5095:
5093:
5090:
5087:
5086:
5083:
5080:
5078:
5075:
5073:
5070:
5068:
5065:
5063:
5060:
5058:
5057:CCL5 (RANTES)
5055:
5053:
5052:CCL4 (MIP-1β)
5050:
5048:
5047:CCL3 (MIP-1α)
5045:
5042:
5041:
5039:
5037:
5033:
5026:
5025:Mogamulizumab
5023:
5020:
5019:
5016:
5013:
5011:
5008:
5006:
5005:CCL5 (RANTES)
5003:
5001:
5000:CCL3 (MIP-1α)
4998:
4995:
4994:
4992:
4990:
4986:
4980:
4977:
4975:
4972:
4970:
4967:
4965:
4962:
4960:
4957:
4955:
4952:
4950:
4947:
4945:
4942:
4940:
4939:CCL5 (RANTES)
4937:
4934:
4933:
4931:
4929:
4925:
4919:
4916:
4913:
4912:
4909:
4906:
4904:
4901:
4899:
4896:
4894:
4891:
4888:
4887:
4885:
4883:
4879:
4873:
4870:
4868:
4865:
4863:
4860:
4858:
4855:
4853:
4850:
4848:
4845:
4843:
4842:CCL5 (RANTES)
4840:
4838:
4837:CCL4 (MIP-1β)
4835:
4832:
4831:
4829:
4827:
4823:
4820:
4818:
4814:
4810:
4807:
4800:
4795:
4793:
4788:
4786:
4781:
4780:
4777:
4761:
4758:
4756:
4753:
4751:
4748:
4746:
4743:
4741:
4738:
4737:
4736:
4729:
4725:
4722:
4720:
4717:
4716:
4715:
4708:
4707:
4706:
4703:
4701:
4698:
4697:
4692:
4689:
4687:
4684:
4683:
4682:
4681:
4677:
4676:
4674:
4668:
4658:
4655:
4653:
4650:
4646:
4643:
4641:
4638:
4637:
4636:
4635:Hematopoietic
4633:
4632:
4630:
4626:
4615:
4611:
4607:
4604:
4603:
4601:
4599:
4595:
4589:
4586:
4584:
4581:
4579:
4576:
4574:
4571:
4569:
4566:
4564:
4561:
4559:
4556:
4554:
4551:
4549:
4546:
4544:
4541:
4539:
4535:
4532:
4531:
4529:
4527:
4523:
4509:
4506:
4505:
4503:
4501:
4497:
4491:
4488:
4486:
4483:
4481:
4478:
4476:
4473:
4471:
4468:
4466:
4463:
4461:
4458:
4456:
4453:
4451:
4448:
4446:
4443:
4441:
4438:
4436:
4433:
4431:
4428:
4426:
4423:
4421:
4418:
4416:
4413:
4412:
4410:
4408:
4404:
4401:
4399:
4395:
4387:
4384:
4382:
4379:
4378:
4377:
4374:
4372:
4369:
4367:
4364:
4362:
4359:
4357:
4354:
4352:
4348:
4345:
4344:
4342:
4340:
4336:
4333:
4331:
4327:
4317:
4314:
4312:
4309:
4307:
4304:
4302:
4299:
4298:
4296:
4292:
4286:
4283:
4281:
4278:
4276:
4273:
4271:
4268:
4267:
4265:
4263:
4259:
4255:
4247:
4244:
4242:
4239:
4237:
4234:
4232:
4228:
4227:
4226:
4223:
4221:
4218:
4216:
4213:
4211:
4208:
4206:
4203:
4202:
4200:
4198:
4193:
4187:
4184:
4182:
4179:
4177:
4174:
4173:
4171:
4169:
4165:
4159:
4156:
4154:
4151:
4149:
4146:
4144:
4140:
4137:
4135:
4131:
4128:
4127:
4125:
4123:
4119:
4116:
4108:
4104:
4101:
4099:
4095:
4089:
4086:
4084:
4081:
4079:
4076:
4074:
4071:
4069:
4066:
4064:
4061:
4059:
4056:
4054:
4051:
4049:
4046:
4044:
4043:TNFSF5/CD40LG
4041:
4039:
4036:
4032:
4029:
4027:
4024:
4023:
4022:
4019:
4017:
4014:
4013:
4011:
4009:
4005:
3995:
3992:
3990:
3987:
3986:
3984:
3980:
3974:
3971:
3970:
3968:
3964:
3958:
3955:
3953:
3950:
3948:
3945:
3943:
3940:
3938:
3935:
3933:
3930:
3928:
3925:
3923:
3920:
3918:
3915:
3913:
3910:
3908:
3905:
3903:
3900:
3898:
3895:
3893:
3890:
3888:
3885:
3883:
3880:
3877:
3874:
3873:
3871:
3867:
3861:
3858:
3856:
3853:
3851:
3848:
3846:
3843:
3841:
3838:
3836:
3833:
3831:
3828:
3826:
3823:
3821:
3818:
3816:
3813:
3810:
3807:
3805:
3802:
3800:
3797:
3795:
3792:
3790:
3787:
3785:
3782:
3780:
3777:
3775:
3772:
3770:
3767:
3765:
3762:
3760:
3757:
3755:
3752:
3749:
3746:
3743:
3740:
3737:
3734:
3731:
3728:
3726:
3723:
3722:
3720:
3716:
3713:
3711:
3707:
3704:
3700:
3696:
3692:
3685:
3680:
3678:
3673:
3671:
3666:
3665:
3662:
3648:
3642:
3637:
3633:
3627:
3622:
3618:
3612:
3607:
3603:
3597:
3592:
3588:
3582:
3577:
3573:
3567:
3562:
3558:
3552:
3547:
3543:
3537:
3532:
3528:
3522:
3517:
3516:
3513:
3504:
3499:
3497:
3492:
3490:
3485:
3484:
3481:
3472:
3468:
3463:
3458:
3454:
3450:
3446:
3442:
3438:
3433:
3429:
3425:
3420:
3415:
3411:
3407:
3406:Cell Research
3403:
3398:
3394:
3390:
3386:
3382:
3377:
3373:
3369:
3364:
3359:
3355:
3351:
3350:Cell Research
3347:
3342:
3338:
3334:
3330:
3326:
3322:
3318:
3313:
3312:
3302:
3298:
3297:
3292:
3288:
3284:
3281:
3277:
3276:
3271:
3270:
3265:
3264:
3251:
3247:
3242:
3237:
3232:
3227:
3223:
3219:
3215:
3208:
3200:
3196:
3191:
3186:
3182:
3178:
3174:
3170:
3166:
3159:
3157:
3148:
3144:
3139:
3134:
3130:
3126:
3122:
3115:
3107:
3103:
3098:
3093:
3089:
3085:
3081:
3074:
3066:
3062:
3057:
3052:
3048:
3044:
3040:
3036:
3032:
3025:
3017:
3013:
3008:
3007:10459.1/68002
3003:
2998:
2993:
2989:
2985:
2981:
2974:
2966:
2962:
2957:
2952:
2948:
2944:
2940:
2933:
2931:
2922:
2918:
2914:
2910:
2906:
2902:
2895:
2887:
2883:
2878:
2873:
2869:
2865:
2861:
2854:
2852:
2850:
2841:
2837:
2832:
2827:
2823:
2819:
2815:
2811:
2807:
2800:
2792:
2791:Science Daily
2788:
2780:
2776:
2771:
2766:
2762:
2758:
2754:
2750:
2746:
2739:
2731:
2727:
2722:
2717:
2713:
2709:
2705:
2698:
2690:
2686:
2682:
2678:
2673:
2668:
2664:
2660:
2656:
2649:
2641:
2637:
2633:
2629:
2625:
2621:
2617:
2613:
2606:
2598:
2594:
2589:
2584:
2581:(1): 93–103.
2580:
2576:
2572:
2565:
2557:
2551:
2547:
2540:
2532:
2528:
2524:
2520:
2515:
2510:
2506:
2502:
2498:
2491:
2483:
2479:
2474:
2469:
2465:
2461:
2457:
2453:
2449:
2442:
2440:
2438:
2436:
2427:
2423:
2418:
2413:
2409:
2405:
2401:
2397:
2393:
2386:
2384:
2382:
2380:
2378:
2369:
2365:
2361:
2357:
2353:
2349:
2345:
2341:
2337:
2333:
2329:
2322:
2320:
2311:
2307:
2303:
2299:
2295:
2291:
2287:
2283:
2276:
2268:
2264:
2260:
2256:
2252:
2248:
2241:
2239:
2237:
2235:
2233:
2231:
2222:
2215:
2207:
2203:
2198:
2193:
2189:
2185:
2181:
2174:
2172:
2170:
2168:
2159:
2155:
2150:
2149:2027.42/28717
2145:
2141:
2137:
2133:
2129:
2122:
2114:
2110:
2104:
2096:
2092:
2086:
2079:
2075:
2070:
2068:
2066:
2058:
2054:
2049:
2047:
2045:
2040:
2030:
2027:
2025:
2022:
2021:
2015:
2013:
2009:
2005:
2001:
1997:
1993:
1989:
1985:
1981:
1976:
1974:
1970:
1966:
1962:
1958:
1957:breast cancer
1953:
1951:
1947:
1943:
1939:
1935:
1931:
1927:
1923:
1919:
1915:
1910:
1908:
1903:
1901:
1897:
1884:
1880:
1876:
1872:
1868:
1864:
1860:
1856:
1852:
1851:
1846:
1842:
1839:
1835:
1831:
1830:
1829:
1826:
1824:
1819:
1817:
1813:
1809:
1805:
1795:
1793:
1792:
1791:Lactobacillus
1787:
1781:
1779:
1775:
1770:
1766:
1762:
1758:
1754:
1750:
1746:
1742:
1737:
1735:
1731:
1727:
1723:
1719:
1715:
1711:
1707:
1703:
1699:
1695:
1691:
1687:
1683:
1679:
1675:
1671:
1667:
1663:
1659:
1655:
1650:
1649:
1645:
1641:
1637:
1633:
1629:
1625:
1621:
1617:
1613:
1609:
1605:
1601:
1597:
1593:
1589:
1585:
1582:
1578:
1574:
1570:
1566:
1556:
1554:
1553:
1548:
1545:xpressed and
1544:
1541:
1539:
1534:
1530:
1526:
1522:
1517:
1515:
1511:
1510:hybridisation
1509:
1504:
1501:
1497:
1493:
1489:
1477:
1472:
1468:
1464:
1461:
1457:
1450:
1448:
1445:
1441:
1437:
1433:
1430:
1426:
1422:
1415:
1413:
1407:
1403:
1400:
1394:
1392:
1388:
1382:
1378:
1375:
1371:
1364:
1362:
1356:
1352:
1349:
1343:
1341:
1337:
1331:
1327:
1324:
1322:RefSeq (mRNA)
1320:
1313:
1312:
1307:
1303:
1300:
1294:
1293:
1288:
1284:
1281:
1279:
1275:
1268:
1267:
1262:
1258:
1255:
1249:
1248:
1244:
1239:
1235:
1232:
1230:
1226:
1219:
1218:
1213:
1209:
1206:
1200:
1199:
1194:
1190:
1187:
1185:
1181:
1178:
1175:
1173:
1170:
1166:
1163:
1159:
1155:
1148:
1144:
1139:
1133:
1130:
1128:
1125:
1123:
1120:
1118:
1115:
1113:
1110:
1108:
1105:
1103:
1100:
1098:
1095:
1093:
1090:
1088:
1085:
1083:
1080:
1078:
1075:
1073:
1070:
1068:
1065:
1063:
1060:
1058:
1055:
1053:
1050:
1048:
1045:
1043:
1040:
1038:
1035:
1033:
1030:
1028:
1025:
1023:
1020:
1018:
1015:
1013:
1010:
1008:
1005:
1003:
1000:
998:
995:
993:
990:
988:
985:
983:
980:
978:
975:
973:
970:
968:
965:
963:
960:
958:
955:
953:
950:
948:
945:
943:
940:
938:
935:
933:
930:
928:
925:
923:
920:
918:
915:
913:
910:
908:
905:
903:
900:
898:
895:
893:
890:
888:
885:
883:
880:
878:
875:
873:
870:
868:
865:
863:
860:
858:
855:
853:
850:
848:
845:
843:
840:
838:
835:
833:
830:
828:
825:
823:
820:
818:
815:
813:
810:
808:
805:
803:
800:
798:
795:
793:
790:
788:
785:
784:
782:
779:
778:
772:
769:
767:
764:
762:
759:
758:
756:
753:
752:
746:
743:
741:
738:
736:
733:
731:
728:
726:
723:
721:
718:
716:
713:
711:
708:
706:
703:
701:
698:
696:
693:
691:
688:
686:
683:
681:
678:
676:
673:
671:
668:
666:
663:
662:
660:
657:
656:
653:
652:Gene ontology
649:
645:
633:
628:
624:
617:
612:
609:
607:
603:
595:
590:
579:
575:
571:
567:
563:
559:
555:
551:
547:
543:
542:
539:
535:
530:
527:
517:
513:
509:
505:
501:
497:
493:
489:
485:
481:
480:
477:
473:
468:
465:
464:
461:
459:
455:
453:
452:
448:
447:
444:
442:
438:
434:
430:
426:
418:
413:
409:
405:
400:
390:
386:
379:
372:
366:
359:
351:
347:
343:
338:
334:
329:
325:
317:
312:
308:
304:
299:
289:
285:
278:
271:
265:
258:
254:
248:
244:
240:
235:
231:
226:
222:
218:
214:
210:
206:
202:
198:
194:
190:
186:
182:
174:
169:
162:
157:
152:
141:
139:
135:
131:
127:
123:
119:
115:
111:
107:
103:
99:
95:
91:
87:
81:
76:
73:
72:
68:
65:
58:
54:
49:
45:
41:
36:
31:
19:
5816:
5795:
5763:
5733:Pateclizumab
5729:
5714:
5680:
5640:
5619:
5598:
5576:
5562:Antagonists:
5561:
5541:
5519:
5489:
5463:
5444:Antagonists:
5443:
5397:CXCL1 (MGSA)
5393:
5363:
5354:Antagonists:
5353:
5333:
5292:Bertilimumab
5288:
5259:
5233:
5212:
5186:
5160:
5139:
5118:
5088:
5056:
5043:
5021:
5004:
4996:
4938:
4935:
4914:
4889:
4852:CCL9 (CCL10)
4841:
4833:
4730:
4709:
4678:
4670:By function/
4381:IL28/IFNL2+3
3747:
3646:
3631:
3616:
3601:
3586:
3571:
3556:
3544:: MET-RANTES
3541:
3526:
3444:
3440:
3409:
3405:
3384:
3380:
3353:
3349:
3320:
3316:
3294:
3274:
3268:
3221:
3217:
3207:
3172:
3168:
3128:
3124:
3114:
3087:
3083:
3073:
3038:
3034:
3024:
2990:(1): 10–13.
2987:
2983:
2973:
2946:
2942:
2904:
2900:
2894:
2867:
2863:
2813:
2809:
2799:
2790:
2752:
2748:
2738:
2711:
2707:
2697:
2662:
2658:
2648:
2615:
2611:
2605:
2578:
2574:
2564:
2545:
2539:
2504:
2500:
2490:
2455:
2451:
2402:(1): 12–27.
2399:
2395:
2335:
2331:
2285:
2281:
2275:
2253:(2): 83–87.
2250:
2246:
2214:
2190:(1): 28–34.
2187:
2183:
2131:
2127:
2121:
2112:
2103:
2094:
2085:
1977:
1954:
1942:CD4+ T-cells
1922:CD8+ T-cells
1911:
1904:
1893:
1875:cytochrome c
1848:
1827:
1820:
1801:
1798:Interactions
1789:
1785:
1782:
1764:
1748:
1741:CC chemokine
1738:
1726:Beta-catenin
1666:thrombocytes
1651:
1648:CD8+ T cells
1600:inflammation
1562:
1550:
1546:
1542:
1537:
1532:
1528:
1527:egulated on
1524:
1520:
1518:
1507:
1499:
1491:
1487:
1486:
1409:
1387:NP_001265665
1384:
1358:
1340:NM_001278736
1333:
1309:
1290:
1264:
1241:
1215:
1196:
1176:
1171:
1047:MAPK cascade
456:
449:
176:External IDs
83:
5825:Resolvin E1
5730:Antibodies:
5664:RTI-5152-12
5580:Ulocuplumab
5577:Antibodies:
5565:Mavorixafor
5520:Antibodies:
5498:CXCL9 (MIG)
5493:CXCL4 (PF4)
5432:Garnocestim
5289:Antibodies:
5119:Antibodies:
5022:Antibodies:
4598:IL17 family
4339:IL10 family
4258:IL12 family
4110:(grouped by
4098:Interleukin
4021:Lymphotoxin
3509:PDB gallery
2618:: 236–245.
1859:neutrophils
1778:translation
1662:fibroblasts
1608:eosinophils
1592:amino acids
1581:chemotactic
1531:ctivation,
576:Paneth cell
518:bone marrow
502:gallbladder
482:granulocyte
415:83,421,344
402:83,416,604
314:35,880,793
301:35,871,491
154:Identifiers
5844:Categories
5644:Conolidine
5112:Vicriviroc
5102:INCB009471
4809:modulators
4705:Lymphokine
4543:IL1B/IL1F2
4538:IL1A/IL1F1
4534:IL1 family
4398:Interferon
4386:IL29/IFNL1
2080:, May 2017
2059:, May 2017
2035:References
2024:Chemotaxis
1948:. In CCL5
1930:granzyme A
1730:cell cycle
1628:mastocytes
1596:leukocytes
1573:N terminus
1565:chemokines
1514:chromosome
962:chemotaxis
842:exocytosis
580:right lung
494:lymph node
460:(ortholog)
197:HomoloGene
5855:Cytokines
5817:Agonists:
5796:Agonists:
5764:Agonists:
5715:Agonists:
5641:Agonists:
5620:Agonists:
5599:Agonists:
5555:Ubiquitin
5542:Agonists:
5523:Eldelumab
5490:Agonists:
5467:Ladarixin
5457:Navarixin
5452:Elubrixin
5447:Danirixin
5427:Emoctakin
5394:Agonists:
5367:Ladarixin
5357:Navarixin
5342:Emoctakin
5334:Agonists:
5282:Ungrouped
5260:Agonists:
5234:Agonists:
5213:Agonists:
5187:Agonists:
5161:Agonists:
5140:Agonists:
5107:Maraviroc
5092:Aplaviroc
5044:Agonists:
4997:Agonists:
4936:Agonists:
4890:Agonists:
4834:Agonists:
4583:33/IL1F11
4548:1Ra/IL1F3
4195:IL6 like/
3912:CXCL8/IL8
3710:Chemokine
3702:By family
3695:cytokines
2206:212858919
2029:Chemokine
1883:caspase-3
1879:caspase-9
1774:cytoplasm
1722:apoptosis
1708:) on the
1632:cytokines
1616:monocytes
1612:basophils
1588:chemokine
1569:cysteines
1412:NP_038681
1391:NP_002976
1361:NM_013653
1336:NM_002985
1162:Orthologs
761:cytoplasm
205:GeneCards
5820:Chemerin
5674:VUF15485
5513:Iroplact
5385:(IL-8Rβ)
5325:(IL-8Rα)
5298:Carlumab
4700:Monokine
4229:+non IL
4114:subunit)
4112:receptor
4083:TNFSF13B
4031:TNFC/LTB
4026:TNFB/LTA
3471:17001303
3428:16354571
3393:15817944
3372:15780175
3337:15142381
3250:21814510
3199:23376885
3147:16807236
3106:10488085
3065:17001303
3016:22265023
2984:Cytokine
2965:11116158
2921:14637022
2886:11449371
2779:20479208
2730:12433367
2708:Immunity
2681:19124744
2640:30184294
2632:11138780
2597:10023774
2575:Immunity
2531:41891558
2482:17322928
2426:34514075
2368:84062618
2310:25389419
2267:11286708
2128:Genomics
2076:–
2055:–
2018:See also
1984:COVID-19
1926:perforin
1855:mitogens
1850:In vitro
1804:interact
1734:Cyclin D
1584:cytokine
1559:Function
1460:Wikidata
1141:Sources:
568:duodenum
514:appendix
506:duodenum
486:monocyte
5122:PRO-140
4588:18/IL1G
4330:Type II
4262:IL12RB1
4168:β chain
4122:γ chain
4078:TNFSF13
4073:TNFSF11
4068:TNFSF10
3750:/RANTES
3462:2014681
3301:PDBe-KB
3291:UniProt
3241:3141034
3190:4003203
3056:2014681
2840:8642344
2831:2192548
2770:2897324
2689:1190644
2523:2456327
2473:2702760
2417:8423937
2360:8525373
2340:Bibcode
2332:Science
2302:8617297
2158:1691736
2078:Ensembl
2057:Ensembl
1834:monomer
1786:in vivo
1747:). The
1654:B-cells
1634:(i.e.,
1604:T cells
1577:protein
1508:in situ
1496:protein
1494:) is a
1278:UniProt
1229:Ensembl
1168:Species
1147:QuickGO
564:jejunum
435:pattern
161:Aliases
5809:CMKLR1
5780:Others
5756:CX3CR1
5698:C (XC)
5659:LIH383
5654:CCX771
5623:CXCL16
5602:CXCL13
4578:IL1F10
4475:IFNA21
4470:IFNA17
4465:IFNA16
4460:IFNA14
4455:IFNA13
4450:IFNA10
4107:Type I
4063:TNFSF9
4058:TNFSF8
4053:TNFSF7
4048:TNFSF6
4038:TNFSF4
3973:CX3CL1
3957:CXCL17
3952:CXCL16
3947:CXCL15
3942:CXCL14
3937:CXCL13
3932:CXCL12
3927:CXCL11
3922:CXCL10
3744:/MIP1β
3738:/MIP1α
3469:
3459:
3426:
3391:
3370:
3335:
3296:P13501
3266:Human
3248:
3238:
3197:
3187:
3145:
3104:
3063:
3053:
3014:
2963:
2919:
2884:
2838:
2828:
2777:
2767:
2728:
2687:
2679:
2638:
2630:
2595:
2552:
2529:
2521:
2480:
2470:
2424:
2414:
2366:
2358:
2308:
2300:
2265:
2204:
2156:
1996:asthma
1710:serine
1610:, and
1535:ormal
1521:RANTES
1490:(also
1446:search
1444:PubMed
1311:P30882
1292:P13501
1184:Entrez
606:BioGPS
556:thymus
548:spleen
498:spleen
185:187011
18:RANTES
5788:CCBP2
5681:PAMs:
5633:CXCR7
5612:CXCR6
5591:CXCR5
5534:CXCR4
5482:CXCR3
5464:NAMs:
5422:CXCL7
5417:CXCL6
5412:CXCL5
5407:CXCL3
5402:CXCL2
5382:CXCR2
5364:NAMs:
5337:CXCL6
5322:CXCR1
5273:CCL25
5268:CCL21
5263:CCL19
5252:CCR11
5242:CCL28
5237:CCL27
5226:CCR10
5216:CCL25
5195:CCL16
5169:CCL21
5164:CCL19
5143:CCL20
5089:NAMs:
5082:CCL16
5077:CCL14
5072:CCL13
5067:CCL11
5015:CCL22
5010:CCL17
4979:CCL28
4974:CCL26
4969:CCL24
4964:CCL18
4959:CCL15
4954:CCL13
4949:CCL11
4915:NAMs:
4908:CCL16
4903:CCL12
4872:CCL23
4867:CCL16
4862:CCL15
4857:CCL14
4640:KITLG
4628:Other
4614:IL17A
4573:IL1F9
4568:IL1F8
4563:IL1F7
4558:IL1F6
4553:IL1F5
4490:IFNW1
4480:IFNB1
4445:IFNA8
4440:IFNA7
4435:IFNA6
4430:IFNA5
4425:IFNA4
4420:IFNA2
4415:IFNA1
4294:Other
4197:gp130
4186:GMCSF
3966:CX3CL
3917:CXCL9
3907:CXCL7
3902:CXCL6
3897:CXCL5
3892:CXCL4
3887:CXCL3
3882:CXCL2
3876:CXCL1
3860:CCL28
3855:CCL27
3850:CCL26
3845:CCL25
3840:CCL24
3835:CCL23
3830:CCL22
3825:CCL21
3820:CCL20
3815:CCL19
3809:CCL18
3804:CCL17
3799:CCL16
3794:CCL15
3789:CCL14
3784:CCL13
3779:CCL12
3774:CCL11
3732:/MCP1
2685:S2CID
2636:S2CID
2527:S2CID
2364:S2CID
2306:S2CID
2202:S2CID
1900:tumor
1871:IFN-γ
1838:dimer
1836:or a
1823:GPR75
1806:with
1745:KLF13
1714:GSK-3
1700:) is
1686:GPCRs
1640:IFN-γ
1571:near
1540:-cell
1217:20304
1177:Mouse
1172:Human
1143:Amigo
560:blood
490:blood
458:Mouse
451:Human
398:Start
333:Mouse
297:Start
293:17q12
230:Human
193:98262
5747:CX3C
5707:XCR1
5205:CCR9
5190:CCL1
5179:CCR8
5153:CCR7
5132:CCR6
5062:CCL8
5036:CCR5
4989:CCR4
4944:CCL7
4928:CCR3
4898:CCL8
4893:CCL2
4882:CCR2
4847:CCL6
4826:CCR1
4760:IL13
4755:IL10
4724:TNFβ
4719:IFNγ
4691:TNFA
4672:cell
4652:SPP1
4610:IL25
4606:IL17
4508:IFNG
4485:IFNK
4371:IL26
4366:IL24
4361:IL20
4356:IL19
4351:IL22
4347:IL10
4316:IL34
4311:IL32
4306:IL16
4301:IL14
4285:IL35
4280:IL27
4275:IL23
4270:IL12
4246:CTF1
4241:CNTF
4225:IL31
4220:IL30
4215:IL27
4210:IL11
4158:IL21
4143:IL13
4134:IL15
4016:TNFA
3994:XCL2
3989:XCL1
3869:CXCL
3769:CCL9
3764:CCL8
3759:CCL7
3754:CCL6
3748:CCL5
3742:CCL4
3736:CCL3
3730:CCL2
3725:CCL1
3647:1u4r
3632:1u4p
3617:1u4m
3602:1u4l
3587:1rto
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