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Peter Hegemann

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245: 583:, Georg Nagel and Ernst Bamberg, which found light could lead to action potential in cultured neurons expressing channelrhodopsin. Teaming up with Deisseroth, Hegemann continued advancing optogenetics by developing rhodopsin variants that could react faster and more accurately, detect different wavelengths of light and conduct different ions. 2147:
Yizhar, Ofer; Fenno, Lief E.; Prigge, Matthias; Schneider, Franziska; Davidson, Thomas J.; O’Shea, Daniel J.; Sohal, Vikaas S.; Goshen, Inbal; Finkelstein, Joel; Paz, Jeanne T.; Stehfest, Katja; Fudim, Roman; Ramakrishnan, Charu; Huguenard, John R.; Hegemann, Peter; Deisseroth, Karl (2011).
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Fernandez Lahore, Rodrigo G.; Pampaloni, Niccolò P.; Schiewer, Enrico; Heim, M.-Marcel; Tillert, Linda; Vierock, Johannes; Oppermann, Johannes; Walther, Jakob; Schmitz, Dietmar; Owald, David; Plested, Andrew J. R.; Rost, Benjamin R.; Hegemann, Peter (21 December 2022).
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Wietek, Jonas; Wiegert, J. Simon; Adeishvili, Nona; Schneider, Franziska; Watanabe, Hiroshi; Tsunoda, Satoshi P.; Vogt, Arend; Elstner, Marcus; Oertner, Thomas G.; Hegemann, Peter (25 April 2014).
3576: 2261: 859: 3586: 502:. Hegemann continued characterizing this rhodopsin after returning to Germany. Working on another green alga, he found that it had a fast electrical response (by ion movement through 2297: 2231: 3581: 1000: 3591: 1169:"The photocycle of the chloride pump halorhodopsin. I: Azidecatalyzed deprotonation of the chromophore is a side reaction of photocycle intermediates inactivating the pump" 3566: 560:
ions can enter the neurons, creating a more positive electric potential inside the neurons and activating them. This is the opposite effect of halorhodopsin activation.
549:. Upon blue light stimulation, electrical currents was detected in the oocytes. When channelrhodopsins are expressed in neurons and stimulated, the ion channel opens so 796: 2761: 3571: 1713: 645: 1913: 1602:
Nagel, Georg; Szellas, Tanjef; Huhn, Wolfram; Kateriya, Suneel; Adeishvili, Nona; Berthold, Peter; Ollig, Doris; Hegemann, Peter; Bamberg, Ernst (2003).
333:. Many in his immediate and extended family are doctors, including his parents, brother, and both grandfathers. He was educated in a humanities-oriented 826: 2413: 3596: 2473: 2205: 2272: 1608: 918: 867: 2914: 2235: 1977:
Zhang, Feng; Prigge, Matthias; Beyrière, Florent; Tsunoda, Satoshi P.; Mattis, Joanna; Yizhar, Ofer; Hegemann, Peter; Deisseroth, Karl (2008).
700: 314: 112: 2850: 2507: 2735: 270:(born 11 December 1954) is a Hertie Senior Research Chair for Neurosciences and a professor of Experimental Biophysics at the Department of 2592: 2305: 2239: 3616: 2503: 2705: 2798: 2675: 1785:"Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin" 1004: 2791: 571:, their movement can be controlled with light stimulation. This came in the same year as another study by a collaboration between 2443: 2387: 639: 2417: 364: 75: 2533: 2679: 712: 615: 2383: 1220: 3561: 2566: 1540:
Nagel, Georg; Ollig, Doris; Fuhrmann, Markus; Kateriya, Suneel; Musti, Anna Maria; Bamberg, Ernst; Hegemann, Peter (2002).
1086: 893: 403: 375: 195: 71: 2824: 804: 770: 1721: 676: 128: 2769: 2907: 2206:"Ninth Annual Wiley Prize in Biomedical Sciences Awarded to Dr. Peter Hegemann, Dr. Georg Nagel, and Dr. Ernst Bamberg" 739: 2537: 1436: 591: 1432:"Karl Deisseroth, Peter Hegemann, and Dieter Oesterhelt receive the 2021 Albert Lasker Basic Medical Research Award" 3606: 627: 213:
Halorhodopsin, die lichtgetriebene Chloridpumpe in Halobacterium halobium: Untersuchungen zur Struktur und Funktion
148: 1754: 2792:"Karl Deisseroth, Peter Hegemann and Gero Miesenböck Awarded Horwitz Prize for Foundational Work on Optogenetics" 1952: 1779:
Li, Xiang; Gutierrez, Davina V.; Hanson, M. Gartz; Han, Jing; Mark, Melanie D.; Chiel, Hillel; Hegemann, Peter;
3386: 2709: 688: 120: 3601: 3556: 2900: 2477: 1121:"The chromoprotein of halorhodopsin is the light-driven electrogenic chloride pump in Halobacterium halobium" 800: 418: 279: 187: 830: 506:) to light stimulation, and proposed that the ion channel and the light-detecting rhodopsin were one single 442: 398:
in Kenneth W. Foster's lab for a year. After returning to Germany, he was offered a five-year position as a
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Using optogenetic techniques, Hegemann and collaborators have confirmed that the unbalanced activity of
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Foster, Kenneth W.; Saranak, Jureepan; Patel, Nayana; Zarilli, Gerald; Okabe, Masami; Kline, Toni;
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took off from these discoveries. In 2005, Hegemann reported expressing channelrhodopsin in chicken
414: 191: 2858: 356: 79: 3418: 3259: 2739: 2624:"2018 Gairdner Awards: The past, present and future of light-gated ion channels and optogenetics" 2540: 1493: 889: 499: 462: 395: 290: 2600: 1979:"Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri" 254: 3551: 1125: 399: 2511: 3122: 2150:"Neocortical excitation/inhibition balance in information processing and social dysfunction" 1031: 466:, discovering that yellow light activates halorhodopsin. When halorhodopsin is expressed in 3546: 3141: 2713: 2161: 2095: 2039: 1912:; Yizhar, Ofer; Berndt, André; Sohal, Vikaas S.; Deisseroth, Karl; Hegemann, Peter (2010). 1796: 1617: 1553: 1384: 1273: 1045: 486: 37:
Hegemann receiving the Hertie Senior Research Chair Professorship for Neurosciences in 2015
8: 3484: 3422: 3195: 3092: 2883: 2795: 2683: 2596: 1859: 1375: 1256:"A rhodopsin is the functional photoreceptor for phototaxis in the unicellular eukaryote 546: 482: 391: 335: 199: 2165: 2099: 2043: 1800: 1621: 1557: 1388: 1277: 1049: 250: 3494: 3221: 3191: 3044: 2986: 2802: 2652: 2623: 2358: 2182: 2149: 2124: 2083: 2003: 1978: 1944: 1884: 1819: 1784: 1780: 1746: 1694: 1577: 1517: 1488: 1460: 1431: 1407: 1366: 1297: 1224: 1187: 982: 670: 587: 471: 470:
and activated by light, the influx of chloride ions shifts the neuron to more negative
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against the gradient. As part of his PhD project, he characterized this protein in
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began in his PhD years, when he investigated the structure and function of
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by applying light. He has received numerous accolades, including the
2028:"Conversion of Channelrhodopsin into a Light-Gated Chloride Channel" 1994: 1932: 3014: 2262:"Liste der mit dem Gottfried Wilhelm Leibniz-Preis Ausgezeichneten" 1872: 454: 344: 2208:(Press release). Wiley Foundation. 1 February 2010. Archived from 2447: 1542:"Channelrhodopsin-1: A Light-Gated Proton Channel in Green Algae" 651: 553: 446: 275: 271: 32: 3612:
Recipients of the Albert Lasker Award for Basic Medical Research
2025: 1367:"Two Light-Activated Conductances in the Eye of the Green Alga 568: 557: 542: 498:. This also prompted Hegemann to spend a year with Foster as a 467: 330: 302: 297:, thereby serving as a light sensor. This created the field of 206: 3577:
Members of the German National Academy of Sciences Leopoldina
2628: 537:, the next year. In both studies, they cloned the genes from 390:
Having won a fellowship for his PhD thesis, Hegemann went to
522: 347:. He liked science subjects and was at first interested in 2146: 1976: 1539: 374:
After graduating in 1980, Hegemann pursued his PhD at the
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Members of the United States National Academy of Sciences
1908: 1249: 1166: 1111: 1025: 457: 1601: 2827:. American Academy of Arts and Sciences. Archived from 1841: 301:, a technique that controls the activities of specific 3582:
Members of the European Molecular Biology Organization
1089:. Max Planck Institute of Biochemistry. Archived from 2762:"Light-sensitive microbial proteins and optogenetics" 646:
Berlin-Brandenburg Academy of Sciences and Humanities
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Fellows of the American Academy of Arts and Sciences
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Kolbe, Michael; Besir, HĂĽseyin; Essen, Lars-Oliver;
654:(German National Academy of Science and Engineering) 3567:
Academic staff of the Humboldt University of Berlin
2329:"The Brain Prize 2013: the optogenetics revolution" 799:. Department of Biology, Faculty of Life Sciences, 521:, Hegemann made the landmark identification of the 1167:Hegemann, P.; Oesterhelt, D.; Steiner, M. (1985). 3538: 2736:"The 2020 Prize in Life Science & Medicine" 1789:Proceedings of the National Academy of Sciences 1609:Proceedings of the National Academy of Sciences 421:in 2004 and became a professor of Experimental 3572:Academic staff of the University of Regensburg 2236:German National Academy of Sciences Leopoldina 701:Albert Lasker Award for Basic Medical Research 315:Albert Lasker Award for Basic Medical Research 113:Albert Lasker Award for Basic Medical Research 2908: 2326: 1482: 1364: 1365:Braun, Franz-Josef; Hegemann, Peter (1999). 765: 763: 761: 711:2022 – International Honorary Member of the 282:, Germany. He is known for his discovery of 409:In 1993, Hegemann joined the Department of 320: 2915: 2901: 2327:Reiner, Andreas; Isacoff, Ehud Y. (2013). 489:would also serve as light detector in the 31: 2651: 2641: 2534:"Massry Prize Winners ( 1996 – Present )" 2508:Technion – Israel Institute of Technology 2181: 2123: 2002: 1818: 1808: 1680: 1639: 1629: 1516: 1506: 1459: 1449: 1406: 1396: 1341: 1196: 1186: 968: 854: 852: 850: 848: 758: 478:generation and inactivating the neurons. 2922: 2621: 1662: 1489:"From channelrhodopsins to optogenetics" 3597:Gottfried Wilhelm Leibniz Prize winners 2738:. Shaw Prize Foundation. Archived from 2388:European Molecular Biology Organization 1711: 695:Shaw Prize in Life Science and Medicine 640:European Molecular Biology Organization 481:A 1984 article by Kenneth W. Foster of 311:Shaw Prize in Life Science and Medicine 117:Shaw Prize in Life Science and Medicine 3539: 2418:Berlin-Brandenburg Academy of Sciences 1321: 845: 594:neurons causes behavioral deficits of 365:Ludwig Maximilian University of Munich 76:Ludwig Maximilian University of Munich 2896: 2680:American Academy of Arts and Sciences 1429: 773:. Lundbeck Foundation. Archived from 713:American Academy of Arts and Sciences 616:German Academy of Sciences Leopoldina 601: 433:Hegemann's research into light-gated 913: 911: 894:Max Planck Institute of Biochemistry 404:Max Planck Institute of Biochemistry 376:Max Planck Institute of Biochemistry 196:Max Planck Institute of Biochemistry 72:Max Planck Institute of Biochemistry 1722:The New England Journal of Medicine 1714:"Optogenetics – The Might of Light" 1003:. Hertie Foundation. Archived from 717:2022 – International Member of the 677:Canada Gairdner International Award 129:Canada Gairdner International Award 13: 3617:European Research Council grantees 2801:. 7 September 2022. Archived from 2480:. 19 December 2014. Archived from 1188:10.1002/j.1460-2075.1985.tb03937.x 610:Wiley Prize in Biomedical Sciences 157:Wiley Prize in Biomedical Sciences 14: 3628: 2877: 2682:. 30 January 2019. Archived from 2538:University of Southern California 1437:Journal of Clinical Investigation 908: 860:"Autobiography of Peter Hegemann" 529:. The team identified the second 1849:; Bamberg, Ernst; Nagel, Georg; 1221:"Light switches for nerve cells" 628:Louis-Jeantet Prize for Medicine 525:for this rhodopsin and named it 417:as a professor. He moved to the 243: 149:Louis-Jeantet Prize for Medicine 2843: 2817: 2784: 2754: 2728: 2698: 2668: 2615: 2585: 2559: 2526: 2496: 2466: 2436: 2406: 2376: 2320: 2290: 2254: 2224: 2198: 2140: 2074: 2019: 1970: 1914:"Ultrafast optogenetic control" 1902: 1835: 1772: 1705: 1656: 1595: 1533: 1476: 1423: 1358: 1315: 1243: 1213: 1160: 1105: 1079: 1019: 1001:"Overview of All Award Winners" 890:"Dieter Oesterhelt (1940–2022)" 622:Gottfried Wilhelm Leibniz Prize 453:that uses light energy to move 153:Gottfried Wilhelm Leibniz Prize 2710:Warren Alpert Foundation Prize 2304:. October 2017. Archived from 1227:. 6 April 2010. Archived from 993: 943: 882: 819: 789: 732: 689:Warren Alpert Foundation Prize 121:Warren Alpert Foundation Prize 1: 2478:Humboldt University of Berlin 2476:(Press release) (in German). 1663:Friedman, Jeffery M. (2021). 1398:10.1016/S0006-3495(99)77326-1 1058:10.1126/science.288.5470.1390 801:Humboldt University of Berlin 725: 419:Humboldt University of Berlin 367:two years later to switch to 355:. Eventually, he went to the 280:Humboldt University of Berlin 188:Humboldt University of Berlin 2855:National Academy of Sciences 2622:Josselyn, Sheena A. (2018). 719:National Academy of Sciences 513:In 2002, collaborating with 349:discovery of new territories 7: 3562:Syracuse University faculty 1783:; Herlitze, Stefan (2005). 924:. NeuroCure. Archived from 829:. UniSysCat. Archived from 428: 10: 3633: 2444:"Prof. Dr. Peter Hegemann" 2347:10.1016/j.tins.2013.08.005 2298:"Professor Peter HEGEMANN" 2269:German Research Foundation 2232:"Prof. Dr. Peter Hegemann" 2108:10.1038/s41467-022-35373-4 1682:10.1016/j.cell.2021.08.022 1343:10.1016/j.cell.2021.08.009 970:10.1016/j.cell.2021.08.011 827:"Prof. Dr. Peter Hegemann" 707:Louisa Gross Horwitz Prize 541:and expressed them in the 109:Louisa Gross Horwitz Prize 3351: 3132: 2931: 1712:Häusser, Michael (2021). 742:. SPP1926. Archived from 539:Chlamydomonas reinhardtii 495:Chlamydomonas reinhardtii 385: 378:in the research group of 235: 223: 205: 183: 169: 162: 104: 96: 85: 67: 42: 30: 23: 2886:publications indexed by 2302:Louis-Jeantet Foundation 951:"A curious color change" 415:University of Regensburg 341:humanistisches Gymnasium 329:in 1954, but grew up in 321:Early life and education 192:University of Regensburg 3607:Massry Prize recipients 3419:Demetrios Christodoulou 3260:Everett Peter Greenberg 2541:Keck School of Medicine 2334:Trends in Neurosciences 2052:10.1126/science.1249375 1810:10.1073/pnas.0509030102 1735:10.1056/NEJMcibr2111915 1631:10.1073/pnas.1936192100 1566:10.1126/science.1072068 1494:EMBO Molecular Medicine 1430:Conti, Lisa R. (2021). 1322:Neuman, Nicole (2021). 963:(21): 5286–5288. 2021. 463:Halobacterium salinarum 1508:10.1002/emmm.201202387 797:"Prof. Peter Hegemann" 443:active ion transporter 400:principal investigator 363:, transferring to the 3123:Shrinivas R. Kulkarni 2799:Irving Medical Center 2088:Nature Communications 1324:"Unexpected pairings" 864:Shaw Prize Foundation 644:2014 – Member of the 638:2014 - Member of the 614:2012 – Member of the 357:University of MĂĽnster 325:Hegemann was born in 80:University of MĂĽnster 3602:Harvey Prize winners 3557:German biophysicists 3182:Keith H. S. Campbell 3142:Stanley Norman Cohen 2567:"Previous Laureates" 3485:Alexander Beilinson 3423:Richard S. Hamilton 3093:Chryssa Kouveliotou 2796:Columbia University 2643:10.7554/eLife.42367 2597:Gairdner Foundation 2174:10.1038/nature10360 2166:2011Natur.477..171Y 2100:2022NatCo..13.7844F 2044:2014Sci...344..409W 1983:Nature Neuroscience 1921:Nature Neuroscience 1860:Nature Neuroscience 1801:2005PNAS..10217816L 1795:(49): 17816–17821. 1781:Landmesser, Lynn T. 1760:on 22 December 2022 1622:2003PNAS..10013940N 1616:(24): 13940–13945. 1558:2002Sci...296.2395N 1552:(5577): 2395–2398. 1389:1999BpJ....76.1668B 1376:Biophysical Journal 1278:1984Natur.311..756F 1231:on 17 December 2022 1139:10.1021/bi00320a050 1093:on 16 December 2022 1050:2000Sci...288.1390K 1044:(5470): 1390–1396. 1007:on 14 December 2022 931:on 13 December 2022 833:on 28 December 2022 807:on 28 December 2022 547:African clawed frog 500:postdoctoral fellow 483:Syracuse University 445:found in a type of 396:postdoctoral fellow 392:Syracuse University 200:Syracuse University 16:German biophysicist 3495:Jean-Michel Bismut 3222:Franz-Ulrich Hartl 3045:William J. Borucki 2861:on 6 December 2022 2831:on 6 December 2022 2805:on 6 December 2022 2772:on 5 December 2022 2742:on 5 December 2022 2716:on 6 December 2022 2686:on 6 December 2022 2603:on 6 December 2022 2573:on 5 December 2022 2547:on 5 December 2022 2514:on 5 December 2022 2484:on 5 December 2022 2454:on 5 December 2022 2394:on 5 December 2022 2308:on 5 December 2022 2278:on 5 December 2022 2242:on 5 December 2022 2212:on 5 December 2022 1958:on 5 December 2022 1225:Max Planck Society 1028:Oesterhelt, Dieter 870:on 5 December 2022 777:on 5 December 2022 746:on 5 December 2022 671:Otto Warburg Medal 602:Honours and awards 551:positively charged 535:Channelrhodopsin-2 527:Channelrhodopsin-1 472:electric potential 253:has a profile for 133:Otto Warburg Medal 3534: 3533: 3515:Vladimir Drinfeld 3361:Shiing-Shen Chern 3318:Paul A. Negulescu 3226:Arthur L. Horwich 3099:Lennart Lindegren 3031:Daniel Eisenstein 2766:Lasker Foundation 2678:(Press release). 2160:(7363): 171–178. 2038:(6182): 409–412. 1910:Gunaydin, Lisa A. 1843:Boyden, Edward S. 1729:(17): 1623–1626. 1675:(21): 5266–5270. 1483:Hegemann, Peter; 1451:10.1172/JCI154418 1336:(21): 5289–5292. 1272:(5988): 756–759. 1133:(24): 6216–6221. 896:. 5 December 2022 892:(Press release). 650:2014 – Member of 380:Dieter Oesterhelt 359:in 1975 to study 345:classical studies 259: 239: 238: 230:Dieter Oesterhelt 164:Scientific career 3624: 3479:Michel Talagrand 3429:Maxim Kontsevich 3383:Robert Langlands 3322:Michael J. Welsh 3286:Mary-Claire King 3240:Michael W. Young 3212:Ruslan Medzhitov 3196:Jeffrey Friedman 3172:Robert Lefkowitz 3160:Michael Berridge 3117:Maura McLaughlin 3103:Michael Perryman 2917: 2910: 2903: 2894: 2893: 2871: 2870: 2868: 2866: 2857:. Archived from 2851:"Peter Hegemann" 2847: 2841: 2840: 2838: 2836: 2825:"Peter Hegemann" 2821: 2815: 2814: 2812: 2810: 2788: 2782: 2781: 2779: 2777: 2768:. Archived from 2758: 2752: 2751: 2749: 2747: 2732: 2726: 2725: 2723: 2721: 2712:. Archived from 2706:"Peter Hegemann" 2702: 2696: 2695: 2693: 2691: 2672: 2666: 2665: 2655: 2645: 2619: 2613: 2612: 2610: 2608: 2599:. Archived from 2593:"Peter Hegemann" 2589: 2583: 2582: 2580: 2578: 2563: 2557: 2556: 2554: 2552: 2543:. Archived from 2530: 2524: 2523: 2521: 2519: 2510:. Archived from 2500: 2494: 2493: 2491: 2489: 2470: 2464: 2463: 2461: 2459: 2450:. Archived from 2440: 2434: 2433: 2431: 2429: 2420:. Archived from 2414:"Peter Hegemann" 2410: 2404: 2403: 2401: 2399: 2390:. Archived from 2384:"Peter Hegemann" 2380: 2374: 2373: 2371: 2369: 2324: 2318: 2317: 2315: 2313: 2294: 2288: 2287: 2285: 2283: 2277: 2271:. Archived from 2266: 2258: 2252: 2251: 2249: 2247: 2238:. 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Archived from 1718: 1709: 1703: 1702: 1684: 1660: 1654: 1653: 1643: 1633: 1599: 1593: 1592: 1590: 1588: 1537: 1531: 1530: 1520: 1510: 1480: 1474: 1473: 1463: 1453: 1427: 1421: 1420: 1410: 1400: 1383:(3): 1668–1678. 1362: 1356: 1355: 1345: 1319: 1313: 1312: 1310: 1308: 1286:10.1038/311756a0 1247: 1241: 1240: 1238: 1236: 1217: 1211: 1210: 1200: 1190: 1181:(9): 2347–2350. 1174:The EMBO Journal 1164: 1158: 1157: 1155: 1153: 1115:; Hegemann, P.; 1109: 1103: 1102: 1100: 1098: 1083: 1077: 1076: 1074: 1072: 1023: 1017: 1016: 1014: 1012: 997: 991: 990: 972: 947: 941: 940: 938: 936: 930: 923: 919:"Peter Hegemann" 915: 906: 905: 903: 901: 886: 880: 879: 877: 875: 866:. Archived from 856: 843: 842: 840: 838: 823: 817: 816: 814: 812: 803:. Archived from 793: 787: 786: 784: 782: 771:"Peter Hegemann" 767: 756: 755: 753: 751: 740:"Peter Hegemann" 736: 596:mental disorders 531:channelrhodopsin 476:action potential 351:and then in the 284:channelrhodopsin 257: 247: 246: 225:Doctoral advisor 219: 91:channelrhodopsin 53:11 December 1954 52: 50: 35: 21: 20: 3632: 3631: 3627: 3626: 3625: 3623: 3622: 3621: 3537: 3536: 3535: 3530: 3509:Ehud Hrushovski 3473:Luis Caffarelli 3407:Clifford Taubes 3403:Simon Donaldson 3393:Vladimir Arnold 3353: 3347: 3338:Stuart H. Orkin 3298:Gero Miesenböck 3236:Michael Rosbash 3232:Jeffrey C. Hall 3192:Douglas Coleman 3186:Shinya Yamanaka 3134: 3128: 3083:Roger Blandford 3077:Edward C. Stone 3071:Jean-Loup Puget 3039:John A. Peacock 3011:David C. Jewitt 2987:Charles Bennett 2975:Reinhard Genzel 2969:Peter Goldreich 2955:Saul Perlmutter 2927: 2921: 2880: 2875: 2874: 2864: 2862: 2849: 2848: 2844: 2834: 2832: 2823: 2822: 2818: 2808: 2806: 2790: 2789: 2785: 2775: 2773: 2760: 2759: 2755: 2745: 2743: 2734: 2733: 2729: 2719: 2717: 2704: 2703: 2699: 2689: 2687: 2674: 2673: 2669: 2620: 2616: 2606: 2604: 2591: 2590: 2586: 2576: 2574: 2565: 2564: 2560: 2550: 2548: 2532: 2531: 2527: 2517: 2515: 2504:"Prize Winners" 2502: 2501: 2497: 2487: 2485: 2472: 2471: 2467: 2457: 2455: 2442: 2441: 2437: 2427: 2425: 2424:on 25 June 2022 2412: 2411: 2407: 2397: 2395: 2382: 2381: 2377: 2367: 2365: 2341:(10): 557–560. 2325: 2321: 2311: 2309: 2296: 2295: 2291: 2281: 2279: 2275: 2264: 2260: 2259: 2255: 2245: 2243: 2230: 2229: 2225: 2215: 2213: 2204: 2203: 2199: 2145: 2141: 2079: 2075: 2024: 2020: 1995:10.1038/nn.2120 1975: 1971: 1961: 1959: 1955: 1933:10.1038/nn.2495 1916: 1907: 1903: 1893: 1891: 1840: 1836: 1777: 1773: 1763: 1761: 1757: 1716: 1710: 1706: 1661: 1657: 1600: 1596: 1586: 1584: 1538: 1534: 1481: 1477: 1444:(19): e154418. 1428: 1424: 1363: 1359: 1320: 1316: 1306: 1304: 1252:Nakanishi, Koji 1248: 1244: 1234: 1232: 1219: 1218: 1214: 1165: 1161: 1151: 1149: 1110: 1106: 1096: 1094: 1087:"Halorhodopsin" 1085: 1084: 1080: 1070: 1068: 1024: 1020: 1010: 1008: 999: 998: 994: 949: 948: 944: 934: 932: 928: 921: 917: 916: 909: 899: 897: 888: 887: 883: 873: 871: 858: 857: 846: 836: 834: 825: 824: 820: 810: 808: 795: 794: 790: 780: 778: 769: 768: 759: 749: 747: 738: 737: 733: 728: 723: 634:The Brain Prize 604: 573:Karl Deisseroth 508:protein complex 485:suggested that 431: 388: 323: 265: 264: 263: 256:Peter Hegemann 248: 244: 217: 198: 194: 190: 176: 155: 151: 147: 145:The Brain Prize 143: 139: 135: 131: 127: 123: 119: 115: 111: 78: 74: 68:Alma mater 63: 59: 54: 48: 46: 38: 26: 17: 12: 11: 5: 3630: 3620: 3619: 3614: 3609: 3604: 3599: 3594: 3589: 3584: 3579: 3574: 3569: 3564: 3559: 3554: 3549: 3532: 3531: 3529: 3528: 3522: 3519:Shing-Tung Yau 3512: 3502: 3492: 3482: 3476: 3470: 3460: 3454: 3451:Henryk Iwaniec 3444: 3441:George Lusztig 3438: 3432: 3426: 3416: 3410: 3400: 3397:Ludwig Faddeev 3390: 3387:Richard Taylor 3380: 3370: 3364: 3357: 3355: 3349: 3348: 3346: 3345: 3342:Swee Lay Thein 3335: 3328:Patrick Cramer 3325: 3315: 3309: 3302:Peter Hegemann 3295: 3289: 3283: 3276:Ian R. Gibbons 3273: 3263: 3256:Bonnie Bassler 3253: 3246:Kazutoshi Mori 3243: 3229: 3219: 3208:Jules Hoffmann 3205: 3199: 3189: 3175: 3169: 3163: 3157: 3138: 3136: 3130: 3129: 3127: 3126: 3120: 3113:Duncan Lorimer 3109:Matthew Bailes 3106: 3096: 3089:Victoria Kaspi 3086: 3080: 3074: 3068: 3062: 3048: 3042: 3028: 3025:John F. Hawley 3018: 3008: 3005:Gerald Fishman 2998: 2984: 2978: 2972: 2966: 2952: 2945:Geoffrey Marcy 2942: 2935: 2933: 2929: 2928: 2920: 2919: 2912: 2905: 2897: 2891: 2890: 2888:Google Scholar 2884:Peter Hegemann 2879: 2878:External links 2876: 2873: 2872: 2842: 2816: 2783: 2753: 2727: 2697: 2667: 2614: 2584: 2558: 2525: 2495: 2465: 2435: 2405: 2375: 2319: 2289: 2253: 2223: 2197: 2139: 2073: 2018: 1989:(6): 631–633. 1969: 1927:(3): 387–392. 1901: 1873:10.1038/nn1525 1834: 1771: 1704: 1655: 1594: 1532: 1501:(2): 173–176. 1475: 1422: 1369:Volvox carteri 1357: 1314: 1242: 1212: 1159: 1117:Oesterhelt, D. 1104: 1078: 1018: 992: 942: 907: 881: 844: 818: 788: 757: 730: 729: 727: 724: 722: 721: 715: 709: 703: 697: 691: 685: 679: 673: 667: 661: 655: 648: 642: 636: 630: 624: 618: 612: 605: 603: 600: 430: 427: 387: 384: 322: 319: 268:Peter Hegemann 249: 242: 241: 240: 237: 236: 233: 232: 227: 221: 220: 209: 203: 202: 185: 181: 180: 171: 167: 166: 160: 159: 106: 102: 101: 98: 94: 93: 87: 86:Known for 83: 82: 69: 65: 64: 55: 44: 40: 39: 36: 28: 27: 25:Peter Hegemann 24: 15: 9: 6: 4: 3: 2: 3629: 3618: 3615: 3613: 3610: 3608: 3605: 3603: 3600: 3598: 3595: 3593: 3590: 3588: 3585: 3583: 3580: 3578: 3575: 3573: 3570: 3568: 3565: 3563: 3560: 3558: 3555: 3553: 3552:Living people 3550: 3548: 3545: 3544: 3542: 3526: 3523: 3520: 3516: 3513: 3510: 3506: 3503: 3500: 3496: 3493: 3490: 3489:David Kazhdan 3486: 3483: 3480: 3477: 3474: 3471: 3468: 3467:Claire Voisin 3464: 3461: 3458: 3457:Nigel Hitchin 3455: 3452: 3448: 3447:Gerd Faltings 3445: 3442: 3439: 3436: 3433: 3430: 3427: 3424: 3420: 3417: 3414: 3413:Jean Bourgain 3411: 3408: 3404: 3401: 3398: 3394: 3391: 3388: 3384: 3381: 3378: 3374: 3373:David Mumford 3371: 3368: 3365: 3362: 3359: 3358: 3356: 3350: 3343: 3339: 3336: 3333: 3329: 3326: 3323: 3319: 3316: 3313: 3310: 3307: 3303: 3299: 3296: 3293: 3290: 3287: 3284: 3281: 3277: 3274: 3271: 3267: 3264: 3261: 3257: 3254: 3251: 3247: 3244: 3241: 3237: 3233: 3230: 3227: 3223: 3220: 3217: 3216:Bruce Beutler 3213: 3209: 3206: 3203: 3200: 3197: 3193: 3190: 3187: 3183: 3179: 3176: 3173: 3170: 3167: 3166:Xiaodong Wang 3164: 3161: 3158: 3155: 3151: 3147: 3146:Herbert Boyer 3143: 3140: 3139: 3137: 3131: 3124: 3121: 3118: 3114: 3110: 3107: 3104: 3100: 3097: 3094: 3090: 3087: 3084: 3081: 3078: 3075: 3072: 3069: 3066: 3063: 3060: 3056: 3052: 3051:Ronald Drever 3049: 3046: 3043: 3040: 3036: 3032: 3029: 3026: 3022: 3021:Steven Balbus 3019: 3016: 3012: 3009: 3006: 3002: 2999: 2996: 2995:David Spergel 2992: 2988: 2985: 2982: 2979: 2976: 2973: 2970: 2967: 2964: 2963:Brian Schmidt 2960: 2956: 2953: 2950: 2946: 2943: 2940: 2937: 2936: 2934: 2930: 2925: 2918: 2913: 2911: 2906: 2904: 2899: 2898: 2895: 2889: 2885: 2882: 2881: 2860: 2856: 2852: 2846: 2830: 2826: 2820: 2804: 2800: 2797: 2793: 2787: 2771: 2767: 2763: 2757: 2741: 2737: 2731: 2715: 2711: 2707: 2701: 2685: 2681: 2677: 2671: 2663: 2659: 2654: 2649: 2644: 2639: 2635: 2631: 2630: 2625: 2618: 2602: 2598: 2594: 2588: 2572: 2568: 2562: 2546: 2542: 2539: 2535: 2529: 2513: 2509: 2505: 2499: 2483: 2479: 2475: 2469: 2453: 2449: 2445: 2439: 2423: 2419: 2416:(in German). 2415: 2409: 2393: 2389: 2385: 2379: 2364: 2360: 2356: 2352: 2348: 2344: 2340: 2336: 2335: 2330: 2323: 2307: 2303: 2299: 2293: 2274: 2270: 2267:(in German). 2263: 2257: 2241: 2237: 2233: 2227: 2211: 2207: 2201: 2193: 2189: 2184: 2179: 2175: 2171: 2167: 2163: 2159: 2155: 2151: 2143: 2135: 2131: 2126: 2121: 2117: 2113: 2109: 2105: 2101: 2097: 2093: 2089: 2085: 2077: 2069: 2065: 2061: 2057: 2053: 2049: 2045: 2041: 2037: 2033: 2029: 2022: 2014: 2010: 2005: 2000: 1996: 1992: 1988: 1984: 1980: 1973: 1954: 1950: 1946: 1942: 1938: 1934: 1930: 1926: 1922: 1915: 1911: 1905: 1890: 1886: 1882: 1878: 1874: 1870: 1866: 1862: 1861: 1856: 1852: 1848: 1844: 1838: 1830: 1826: 1821: 1816: 1811: 1806: 1802: 1798: 1794: 1790: 1786: 1782: 1775: 1756: 1752: 1748: 1744: 1740: 1736: 1732: 1728: 1724: 1723: 1715: 1708: 1700: 1696: 1692: 1688: 1683: 1678: 1674: 1670: 1666: 1659: 1651: 1647: 1642: 1637: 1632: 1627: 1623: 1619: 1615: 1611: 1610: 1605: 1598: 1583: 1579: 1575: 1571: 1567: 1563: 1559: 1555: 1551: 1547: 1543: 1536: 1528: 1524: 1519: 1514: 1509: 1504: 1500: 1496: 1495: 1490: 1486: 1479: 1471: 1467: 1462: 1457: 1452: 1447: 1443: 1439: 1438: 1433: 1426: 1418: 1414: 1409: 1404: 1399: 1394: 1390: 1386: 1382: 1378: 1377: 1372: 1370: 1361: 1353: 1349: 1344: 1339: 1335: 1331: 1330: 1325: 1318: 1303: 1299: 1295: 1291: 1287: 1283: 1279: 1275: 1271: 1267: 1266: 1261: 1259: 1258:Chlamydomonas 1253: 1246: 1230: 1226: 1222: 1216: 1208: 1204: 1199: 1194: 1189: 1184: 1180: 1176: 1175: 1170: 1163: 1148: 1144: 1140: 1136: 1132: 1128: 1127: 1122: 1118: 1114: 1108: 1092: 1088: 1082: 1067: 1063: 1059: 1055: 1051: 1047: 1043: 1039: 1038: 1033: 1029: 1022: 1006: 1002: 996: 988: 984: 980: 976: 971: 966: 962: 958: 957: 952: 946: 927: 920: 914: 912: 895: 891: 885: 869: 865: 861: 855: 853: 851: 849: 832: 828: 822: 806: 802: 798: 792: 776: 772: 766: 764: 762: 745: 741: 735: 731: 720: 716: 714: 710: 708: 704: 702: 698: 696: 692: 690: 686: 684: 683:Rumford Prize 680: 678: 674: 672: 668: 666: 662: 660: 656: 653: 649: 647: 643: 641: 637: 635: 631: 629: 625: 623: 619: 617: 613: 611: 607: 606: 599: 597: 593: 589: 584: 582: 578: 577:Edward Boyden 574: 570: 566: 563:The field of 561: 559: 555: 552: 548: 544: 540: 536: 532: 528: 524: 520: 519:Ernst Bamberg 516: 511: 509: 505: 501: 497: 496: 492: 488: 484: 479: 477: 474:, preventing 473: 469: 465: 464: 459: 456: 452: 448: 444: 440: 439:halorhodopsin 436: 435:ion transport 426: 424: 420: 416: 412: 407: 405: 401: 397: 394:in 1985 as a 393: 383: 381: 377: 372: 370: 366: 362: 358: 354: 350: 346: 342: 338: 337: 332: 328: 318: 316: 312: 308: 307:Rumford Prize 304: 300: 296: 292: 289: 285: 281: 277: 276:Life Sciences 274:, Faculty of 273: 269: 261: 260: 252: 234: 231: 228: 226: 222: 215: 214: 210: 208: 204: 201: 197: 193: 189: 186: 182: 179: 175: 172: 168: 165: 161: 158: 154: 150: 146: 142: 138: 134: 130: 126: 125:Rumford Prize 122: 118: 114: 110: 107: 103: 99: 95: 92: 89:Discovery of 88: 84: 81: 77: 73: 70: 66: 62: 58: 45: 41: 34: 29: 22: 19: 3525:Peter Sarnak 3499:Jeff Cheeger 3463:János Kollár 3435:David Donoho 3367:Andrew Wiles 3352:Mathematical 3312:Scott D. Emr 3301: 3250:Peter Walter 3202:David Julius 3154:Richard Doll 3150:Yuet-Wai Kan 3135:and medicine 3133:Life science 3059:Rainer Weiss 3001:Enrico Costa 2949:Michel Mayor 2863:. Retrieved 2859:the original 2845: 2833:. Retrieved 2829:the original 2819: 2807:. Retrieved 2803:the original 2786: 2774:. Retrieved 2770:the original 2756: 2744:. Retrieved 2740:the original 2730: 2718:. Retrieved 2714:the original 2700: 2688:. Retrieved 2684:the original 2670: 2633: 2627: 2617: 2605:. Retrieved 2601:the original 2587: 2575:. Retrieved 2571:the original 2561: 2549:. Retrieved 2545:the original 2528: 2516:. Retrieved 2512:the original 2498: 2486:. Retrieved 2482:the original 2468: 2456:. Retrieved 2452:the original 2438: 2426:. Retrieved 2422:the original 2408: 2396:. Retrieved 2392:the original 2378: 2366:. Retrieved 2338: 2332: 2322: 2310:. Retrieved 2306:the original 2292: 2280:. Retrieved 2273:the original 2256: 2244:. Retrieved 2240:the original 2226: 2214:. 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Index


MĂĽnster
Germany
Max Planck Institute of Biochemistry
Ludwig Maximilian University of Munich
University of MĂĽnster
channelrhodopsin
Louisa Gross Horwitz Prize
Albert Lasker Award for Basic Medical Research
Shaw Prize in Life Science and Medicine
Warren Alpert Foundation Prize
Rumford Prize
Canada Gairdner International Award
Otto Warburg Medal
Harvey Prize
Massry Prize
The Brain Prize
Louis-Jeantet Prize for Medicine
Gottfried Wilhelm Leibniz Prize
Wiley Prize in Biomedical Sciences
Biophysics
Optogenetics
Humboldt University of Berlin
University of Regensburg
Max Planck Institute of Biochemistry
Syracuse University
Thesis
Halorhodopsin, die lichtgetriebene Chloridpumpe in Halobacterium halobium: Untersuchungen zur Struktur und Funktion
Doctoral advisor
Dieter Oesterhelt

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