101:
There are several biological mechanisms which may lead to osteolysis. In total hip replacement, the generally accepted explanation for osteolysis involves wear particles (worn off the contact surface of the artificial
293:
62:. Although osteoclasts are active during the natural formation of healthy bone the term "osteolysis" specifically refers to a pathological process. Osteolysis often occurs in the proximity of a
110:
reaction which causes resorption of living bone tissue. Osteolysis has been reported to occur as early as 12 months after implantation and is usually progressive. This may require a revision
145:
readily depicts resorption of the distal clavicle as irregular cortical erosions, whereas the acromion remains intact. Associated findings may include distended joint capsule,
228:
94:, total knee replacements and total shoulder replacements. Osteolysis can also be associated with the radiographic changes seen in those with bisphosphonate-related
262:
936:
369:
1095:
602:
248:
800:
1100:
929:
106:). As the body attempts to clean up these wear particles (typically consisting of plastic or metal), it triggers an
663:
362:
1032:
597:
632:
922:
812:
627:
528:
355:
768:
622:
556:
121:, it can lead to implant loosening or bone breakage, which in turn causes serious medical problems.
858:
718:
590:
417:
308:
129:
Distal clavicular osteolysis (DCO) is often associated with problems weightlifters have with their
883:
479:
436:
142:
130:
493:
406:
261:
Arend CF. Ultrasound of the
Shoulder. Master Medical Books, 2013. Sample chapter available at
734:
511:
103:
91:
651:
607:
8:
1090:
1052:
1037:
817:
566:
160:
163:
of distal clavicle by removing a few millimetres of bone from the very end of the bone.
1105:
1027:
1022:
832:
639:
585:
982:
962:
378:
319:
240:
177:
172:
153:
30:
827:
967:
846:
533:
206:
778:
760:
739:
713:
682:
617:
543:
313:
83:
67:
47:
893:
675:
670:
612:
469:
210:
197:
Sanjeev
Agarwal (2004). "Osteolysis - basic science, incidence and diagnosis".
324:
302:
90:
generally refers to a problem common to artificial joint replacements such as
1084:
1004:
447:
95:
972:
696:
658:
523:
506:
501:
464:
386:
244:
118:
59:
227:
Schwarzkopf R, Ishak C, Elman M, Gelber J, Strauss DN, Jazrawi LM (2008).
1009:
474:
422:
347:
146:
35:
914:
285:
1065:
705:
518:
457:
452:
107:
71:
63:
55:
86:
is commonly associated with many diseases or joint problems, the term
66:
that causes either an immunological response or changes in the bone's
645:
330:
141:. This condition is often referred to as "weight lifter's shoulder".
954:
395:
138:
134:
335:
111:
946:
561:
297:
807:
149:
977:
226:
51:
229:"Distal clavicular osteolysis: a review of the literature"
275:
70:. Osteolysis may also be caused by pathologies like
1082:
222:
220:
196:
124:
159:A common surgery to treat recalcitrant DCO is
930:
363:
217:
133:due to high mechanical stresses put on the
937:
923:
377:
370:
356:
944:
117:Although osteolysis itself is clinically
58:and can be interpreted as the reverse of
603:Hypertrophic pulmonary osteoarthropathy
1083:
918:
351:
77:
16:Breaking down of bone by osteoclasts
13:
74:, cysts, or chronic inflammation.
14:
1117:
271:
114:(replacement of the prosthesis).
664:Infantile cortical hyperostosis
1096:Orthopedic surgical procedures
598:Complex regional pain syndrome
255:
190:
1:
183:
125:Distal clavicular osteolysis
7:
166:
10:
1122:
801:Legg–Calvé–Perthes disease
211:10.1016/j.cuor.2004.03.002
1101:Musculoskeletal disorders
1061:
1048:
1018:
1000:
993:
953:
869:
843:
786:
777:
769:Osteochondritis dissecans
759:
752:
727:
704:
695:
575:
542:
492:
433:
403:
394:
385:
279:
29:
24:
813:Osgood–Schlatter disease
719:Relapsing polychondritis
591:Osteonecrosis of the jaw
418:Osteitis fibrosa cystica
131:acromioclavicular joints
529:Paget's disease of bone
480:Vertebral osteomyelitis
143:Medical ultrasonography
379:Bone and joint disease
92:total hip replacements
859:Scheuermann's disease
735:Slipping rib syndrome
557:Hajdu–Cheney syndrome
137:as it meets with the
104:ball and socket joint
652:Aneurysmal bone cyst
608:Nonossifying fibroma
233:Bull NYU Hosp Jt Dis
199:Current Orthopaedics
1053:End-plate potential
1038:Uterine contraction
1023:Muscle contraction
884:Kienböck's disease
640:Skeletal fluorosis
586:Avascular necrosis
1078:
1077:
1074:
1073:
912:
911:
908:
907:
904:
903:
748:
747:
691:
690:
623:Fibrous dysplasia
488:
487:
345:
344:
251:on March 4, 2016.
178:Biomineralization
173:Osteolytic lesion
154:joint instability
78:Joint replacement
41:
40:
19:Medical condition
1113:
998:
997:
939:
932:
925:
916:
915:
874:
850:
818:Blount's disease
791:
784:
783:
757:
756:
702:
701:
567:Gorham's disease
534:Hypophosphatasia
441:
411:
401:
400:
392:
391:
372:
365:
358:
349:
348:
277:
276:
265:
259:
253:
252:
247:. Archived from
224:
215:
214:
194:
22:
21:
1121:
1120:
1116:
1115:
1114:
1112:
1111:
1110:
1081:
1080:
1079:
1070:
1057:
1044:
1014:
989:
949:
943:
913:
900:
870:
865:
844:
839:
833:Sever's disease
787:
773:
761:Osteochondritis
744:
740:Tietze syndrome
723:
714:Costochondritis
687:
683:Pycnodysostosis
618:Stress fracture
571:
544:Bone resorption
538:
484:
434:
429:
404:
381:
376:
346:
341:
340:
288:
274:
269:
268:
260:
256:
225:
218:
195:
191:
186:
169:
127:
84:bone resorption
80:
68:structural load
20:
17:
12:
11:
5:
1119:
1109:
1108:
1103:
1098:
1093:
1076:
1075:
1072:
1071:
1069:
1068:
1062:
1059:
1058:
1056:
1055:
1049:
1046:
1045:
1043:
1042:
1041:
1040:
1035:
1030:
1019:
1016:
1015:
1013:
1012:
1007:
1001:
995:
991:
990:
988:
987:
986:
985:
980:
975:
965:
959:
957:
951:
950:
945:Physiology of
942:
941:
934:
927:
919:
910:
909:
906:
905:
902:
901:
899:
898:
897:
896:
894:Panner disease
888:
887:
886:
877:
875:
867:
866:
864:
863:
862:
861:
853:
851:
841:
840:
838:
837:
836:
835:
830:
828:Köhler disease
822:
821:
820:
815:
805:
804:
803:
794:
792:
781:
775:
774:
772:
771:
765:
763:
754:
750:
749:
746:
745:
743:
742:
737:
731:
729:
725:
724:
722:
721:
716:
710:
708:
699:
693:
692:
689:
688:
686:
685:
680:
679:
678:
676:Melorheostosis
671:Osteosclerosis
668:
667:
666:
656:
655:
654:
642:
637:
636:
635:
630:
620:
615:
613:Pseudarthrosis
610:
605:
600:
595:
594:
593:
588:
579:
577:
573:
572:
570:
569:
564:
559:
554:
548:
546:
540:
539:
537:
536:
531:
526:
521:
516:
515:
514:
504:
498:
496:
490:
489:
486:
485:
483:
482:
477:
472:
470:Brodie abscess
467:
462:
461:
460:
455:
444:
442:
431:
430:
428:
427:
426:
425:
414:
412:
398:
389:
383:
382:
375:
374:
367:
360:
352:
343:
342:
339:
338:
327:
316:
305:
289:
284:
283:
281:
280:Classification
273:
272:External links
270:
267:
266:
263:ShoulderUS.com
254:
216:
205:(3): 220–231.
188:
187:
185:
182:
181:
180:
175:
168:
165:
126:
123:
79:
76:
39:
38:
33:
27:
26:
18:
15:
9:
6:
4:
3:
2:
1118:
1107:
1104:
1102:
1099:
1097:
1094:
1092:
1089:
1088:
1086:
1067:
1064:
1063:
1060:
1054:
1051:
1050:
1047:
1039:
1036:
1034:
1031:
1029:
1026:
1025:
1024:
1021:
1020:
1017:
1011:
1008:
1006:
1005:Hand strength
1003:
1002:
999:
996:
992:
984:
981:
979:
976:
974:
971:
970:
969:
966:
964:
961:
960:
958:
956:
952:
948:
940:
935:
933:
928:
926:
921:
920:
917:
895:
892:
891:
889:
885:
882:
881:
879:
878:
876:
873:
868:
860:
857:
856:
855:
854:
852:
849:
848:
842:
834:
831:
829:
826:
825:
823:
819:
816:
814:
811:
810:
809:
806:
802:
799:
798:
796:
795:
793:
790:
785:
782:
780:
776:
770:
767:
766:
764:
762:
758:
755:
751:
741:
738:
736:
733:
732:
730:
726:
720:
717:
715:
712:
711:
709:
707:
703:
700:
698:
694:
684:
681:
677:
674:
673:
672:
669:
665:
662:
661:
660:
657:
653:
650:
649:
648:
647:
643:
641:
638:
634:
631:
629:
626:
625:
624:
621:
619:
616:
614:
611:
609:
606:
604:
601:
599:
596:
592:
589:
587:
584:
583:
581:
580:
578:
574:
568:
565:
563:
560:
558:
555:
553:
550:
549:
547:
545:
541:
535:
532:
530:
527:
525:
522:
520:
517:
513:
510:
509:
508:
505:
503:
500:
499:
497:
495:
491:
481:
478:
476:
473:
471:
468:
466:
463:
459:
456:
454:
451:
450:
449:
448:Osteomyelitis
446:
445:
443:
440:
438:
432:
424:
421:
420:
419:
416:
415:
413:
410:
408:
402:
399:
397:
393:
390:
388:
384:
380:
373:
368:
366:
361:
359:
354:
353:
350:
337:
333:
332:
328:
326:
322:
321:
317:
315:
311:
310:
306:
304:
300:
299:
295:
291:
290:
287:
282:
278:
264:
258:
250:
246:
242:
239:(2): 94–101.
238:
234:
230:
223:
221:
212:
208:
204:
200:
193:
189:
179:
176:
174:
171:
170:
164:
162:
157:
155:
151:
148:
144:
140:
136:
132:
122:
120:
115:
113:
109:
105:
99:
97:
96:osteonecrosis
93:
89:
85:
75:
73:
69:
65:
61:
57:
53:
49:
46:is an active
45:
37:
34:
32:
28:
23:
973:Eye movement
871:
845:
788:
659:Hyperostosis
644:
551:
524:Osteomalacia
507:Osteoporosis
502:Bone density
465:Sesamoiditis
435:
405:
396:Inflammation
329:
318:
307:
292:
257:
249:the original
236:
232:
202:
198:
192:
158:
128:
119:asymptomatic
116:
100:
98:of the jaw.
87:
81:
60:ossification
43:
42:
1010:Muscle tone
633:Polyostotic
475:Periostitis
423:Brown tumor
147:soft tissue
72:bone tumors
56:osteoclasts
36:Orthopedics
1091:Geriatrics
1085:Categories
1066:Myogenesis
983:Locomotion
706:Chondritis
628:Monostotic
582:Ischaemia
552:Osteolysis
519:Osteopenia
458:Involucrum
453:Sequestrum
320:DiseasesDB
184:References
108:autoimmune
88:osteolysis
64:prosthesis
54:matrix by
48:resorption
44:Osteolysis
25:Osteolysis
1106:Arthritis
1028:Isometric
646:bone cyst
494:Metabolic
437:infection
407:endocrine
336:203522001
331:SNOMED CT
161:resection
31:Specialty
1033:Isotonic
968:Movement
963:Exercise
955:Exertion
753:Combined
512:Juvenile
245:18537776
167:See also
150:swelling
139:acromion
135:clavicle
947:muscles
314:D010014
112:surgery
890:elbow
880:wrist
562:Ainhum
243:
152:, and
82:While
994:Other
847:spine
824:foot
808:tibia
779:Child
728:Other
697:Joint
576:Other
303:M89.5
978:Gait
872:arm:
797:hip
789:leg:
387:Bone
325:1517
309:MeSH
241:PMID
52:bone
294:ICD
207:doi
50:of
1087::
334::
323::
312::
301::
298:10
237:66
235:.
231:.
219:^
203:18
201:.
156:.
938:e
931:t
924:v
439::
409::
371:e
364:t
357:v
296:-
286:D
213:.
209::
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