1003:). Thus mammalian neurofilaments are heteropolymers of up to five different proteins: NF-L, NF-M, NF-H, α-internexin and peripherin. The five neurofilament proteins can co-assemble in different combinations in different nerve cell types and at different stages of development. The precise composition of neurofilaments in any given nerve cell depends on the relative expression levels of the neurofilament proteins in the cell at that time. For example, NF-H expression is low in developing neurons and increases postnatally in neurons with myelinated axons. In the adult nervous system neurofilaments in small unmyelinated axons contain more peripherin and less NF-H whereas neurofilaments in large myelinated axons contain more NF-H and less peripherin. The type III intermediate filament subunit,
1213:. Two dimers associate in a staggered antiparallel manner to form a tetramer. This tetramer is believed to be the basic subunit (i.e. building block) of the neurofilament. Tetramer subunits associate side-to-side to form unit-length filaments, which then anneal end-to-end to form the mature neurofilament polymer, but the precise organization of these subunits within the polymer is not known, largely because of the heterogeneous protein composition and the inability to crystallize neurofilaments or neurofilament proteins. Structural models generally assume eight tetramers (32 neurofilament polypeptides) in a filament cross-section, but measurements of linear mass density suggest that this can vary.
1340:. The filaments move bidirectionally, i.e. both towards the axon tip (anterograde) and towards the cell body (retrograde), but the net direction is anterograde. The filaments move at velocities of up to 8 μm/s on short time scales (seconds or minutes), with average velocities of approximately 1 μm/s. However, the average velocity on longer time scales (hours or days) is slow because the movements are very infrequent, consisting of brief sprints interrupted by long pauses. Thus on long time scales neurofilaments move in the slow component of axonal transport.
1178:
1277:
1312:
determined by the number of neurofilaments in the axon and their packing density. The number of neurofilaments in the axon is thought to be determined by neurofilament gene expression and axonal transport. The packing density of the filaments is determined by their side-arms which define the spacing between neighboring filaments. Phosphorylation of the sidearms is thought to increase their extensibility, increasing the spacing between neighboring filaments by the binding of divalent cations between the sidearms of adjacent filaments
1230:
1162:
1320:, the diameter of the axon may increase as much as fivefold. This is caused by an increase in the number of neurofilaments exported from the nerve cell body as well as a slowing of their rate of transport. In mature myelinated axons, neurofilaments can be the single most abundant cytoplasmic structure and can occupy most of the axonal cross-sectional area. For example, a large myelinated axon may contain thousands of neurofilaments in one cross-section
1217:
sizes of the neurofilament proteins are largely due to differences in the length of the carboxy terminal domains. These domains are rich in acidic and basic amino acid residues. The carboxy terminal domains of NF-M and NF-H are the longest and are modified extensively by post-translational modifications such as
1216:
The amino terminal domains of the neurofilament proteins contain numerous phosphorylation sites and appear to be important for subunit interactions during filament assembly. The carboxy terminal domains appear to be intrinsically disordered domains that lack alpha helix or beta sheet. The different
1311:
neurons in especially high concentrations in axons, where they are all aligned in parallel along the long axis of the axon forming a continuously overlapping array. They have been proposed to function as space-filling structures that increase axonal diameter. Their contribution to axon diameter is
1396:
of axonal damage in diseases affecting the central nervous system. When neurons or axons degenerate, neurofilament proteins are released into the blood or cerebrospinal fluid. Immunoassays of neurofilament proteins in cerebrospinal fluid and plasma can thus serve as indicators of axonal damage in
1225:
in vivo. They project radially from the filament backbone to form a dense brush border of highly charged and unstructured domains analogous to the bristles on a bottle brush. These entropically flailing domains have been proposed to define a zone of exclusion around each filament, effectively
1135:
is greater than the mass predicted from the amino sequence. This is due to the anomalous electrophoretic migration of these proteins and is particularly extreme for neurofilament proteins NF-M and NF-H due to their high content of charged amino acids and extensive phosphorylation. All three
977:
The protein composition of neurofilaments varies widely across different animal phyla. Most is known about mammalian neurofilaments. Historically, mammalian neurofilaments were originally thought to be composed of just three proteins called neurofilament protein NF-L (low molecular weight;
1185:
stained with an antibody to neurofilament light, NF-L revealed with a brown dye, cell nuclei are revealed with a blue dye. Nuclear rich region at left is granular layer, region at right is molecular layer. The antibody binds processes of basket cells, parallel fiber axons, the perikarya of
1226:
spacing the filaments apart from their neighbors. In this way, the carboxy terminal projections maximize the space-filling properties of the neurofilament polymers. By electron microscopy, these domains appear as projections called sidearms that appear to contact neighboring filaments.
994:
and are often referred to as the "neurofilament triplet". However, it is now clear that neurofilaments also contain the protein α-internexin and that neurofilaments in the peripheral nervous system can also contain the protein peripherin. (this is different from
1315:
Early in development, axons are narrow processes that contain relatively few neurofilaments. Those axons that become myelinated accumulate more neurofilaments, which drives the expansion of their caliber. After an axon has grown and connected with its
1148:
phosphorylation sites. These sites almost all contain the peptide lysine-serine-proline (KSP), and phosphorylation is normally found on axonal and not dendritic neurofilaments. Human NF-M has 13 of these KSP sites, while human NF-H is expressed from two
1169:
and stained, in green, with an antibody to neurofilament subunit NF-L, which reveals a large neuron. The culture was stained in red for α-internexin, which in this culture is found in neuronal stem cells surrounding the large neuron. Image courtesy of
1332:. Most of the neurofilament proteins in axons are synthesized in the nerve cell body, where they rapidly assemble into neurofilament polymers within about 30 minutes. These assembled neurofilament polymers are transported along the axon on
2290:
Rosengren LE, Karlsson JE, Karlsson JO, Persson LI, Wikkelsø C (November 1996). "Patients with amyotrophic lateral sclerosis and other neurodegenerative diseases have increased levels of neurofilament protein in CSF".
918:. The proteins that form neurofilaments are members of the intermediate filament protein family, which is divided into six types based on their gene organization and protein structure. Types I and II are the
1374:. The type VI intermediate filament protein Nestin is expressed in developing neurons and glia. Nestin is considered a marker of neuronal stem cells, and the presence of this protein is widely used to define
2247:
Jonsson M, Zetterberg H, van
Straaten E, Lind K, Syversen S, Edman A, et al. (March 2010). "Cerebrospinal fluid biomarkers of white matter lesions - cross-sectional results from the LADIS study".
1803:
Kushkuley J, Chan WK, Lee S, Eyer J, Leterrier JF, Letournel F, Shea TB (October 2009). "Neurofilament cross-bridging competes with kinesin-dependent association of neurofilaments with microtubules".
2334:
Teunissen CE, Iacobaeus E, Khademi M, Brundin L, Norgren N, Koel-Simmelink MJ, et al. (April 2009). "Combination of CSF N-acetylaspartate and neurofilaments in multiple sclerosis".
1846:
Kushkuley J, Metkar S, Chan WK, Lee S, Shea TB (March 2010). "Aluminum induces neurofilament aggregation by stabilizing cross-bridging of phosphorylated c-terminal sidearms".
1358:
to neurofilament proteins have been developed and are commercially available. These antibodies can be used to detect neurofilament proteins in cells and tissues using
1429:
showed that the NF-L antibodies employed in the most widely used NF-L assays are specific for cleaved forms of NF-L generated by proteolysis induced by cell death. .
1638:"Peripherin is a subunit of peripheral nerve neurofilaments: implications for differential vulnerability of CNS and peripheral nervous system axons"
1540:"The slow component of axonal transport. Identification of major structural polypeptides of the axon and their generality among mammalian neurons"
763:
626:
481:
333:
193:
45:
3434:
5243:
5263:
5195:
5180:
5175:
5170:
5165:
5155:
5076:
4785:
4765:
4735:
4730:
2603:
1007:, is expressed in developing neurons and a few very unusual neurons in the adult in association with type IV proteins, such as the
954:
not found in other intermediate filament gene sequences, suggesting a common evolutionary origin from one primitive type IV gene.
5405:
5400:
5395:
5390:
5145:
5135:
5125:
5120:
5091:
4795:
4790:
3837:
3725:
3715:
3690:
3670:
3574:
3554:
1963:
Wang L, Ho CL, Sun D, Liem RK, Brown A (March 2000). "Rapid movement of axonal neurofilaments interrupted by prolonged pauses".
3797:
768:
2440:"Serum Neurofilament Light Chain as a Predictive Biomarker for Ischemic Stroke Outcome: A Systematic Review and Meta-analysis"
631:
486:
338:
198:
50:
5764:
5759:
5754:
1738:
5769:
5749:
4062:
1756:"Influence of the phosphorylation state of neurofilament proteins on the interactions between purified filaments in vitro"
3427:
787:
650:
505:
357:
217:
69:
1209:
domains that are largely unstructured. The rod domains of two neurofilament proteins dimerize to form an alpha-helical
2528:
Shaw, Gerry; Madorsky, Irina; Li, Ying; Wang, YongSheng; Jorgensen, Marda; Rana, Sabhya; Fuller, David D (2023-03-02).
2198:
2485:
Lalonde R, Strazielle C (2003). "Neurobehavioral characteristics of mice with modified intermediate filament genes".
1898:
1589:"α-internexin is structurally and functionally associated with the neurofilament triplet proteins in the mature CNS"
3227:
3157:
775:
638:
493:
345:
205:
57:
4581:
3222:
3152:
2767:
935:
4850:
4693:
3420:
5729:
5283:
2842:
1418:
1398:
1397:
neurological disorders. NF-L levels in blood and CSF are therefore useful markers for disease monitoring in
1409:. It has also been evaluated as a prognostic marker for functional outcome following acute ischemic stroke.
898:. They are protein polymers measuring 10 nm in diameter and many micrometers in length. Together with
2837:
2825:
2596:
2008:"Kymograph analysis with high temporal resolution reveals new features of neurofilament transport kinetics"
1288:
3990:
2877:
2815:
780:
643:
498:
350:
210:
62:
5461:
2872:
2530:"Uman-type neurofilament light antibodies are effective reagents for the imaging of neurodegeneration"
3382:
3232:
3167:
2795:
1385:. Staining with these antibodies can distinguish neurons (positive for neurofilament proteins) from
966:
915:
887:
5694:
3162:
2888:
1422:
1191:
1171:
2861:
2589:
2439:
1406:
1197:
Like other intermediate filament proteins, the neurofilament proteins all share a common central
1127:
The triplet proteins are named based upon their relative size (low, medium, high). The apparent
3329:
2856:
2620:
2455:
2197:
Khalil M, Teunissen CE, Otto M, Piehl F, Sormani MP, Gattringer T, et al. (October 2018).
1349:
962:
5774:
4113:
3467:
3187:
3177:
3112:
2438:
Liu, Daoshen; Chen, Jing; Wang, Xuanying; Xin, Jialun; Cao, Ruili; Liu, Zhirong (June 2020).
1426:
1296:
700:
696:
551:
403:
407:
4382:
3312:
3209:
3139:
2965:
2820:
2391:
2380:"Tau or neurofilament light-Which is the more suitable biomarker for Huntington's disease?"
1367:
1363:
1177:
837:
833:
263:
115:
1916:"Interval between the synthesis and assembly of cytoskeletal proteins in cultured neurons"
957:
Any proteinaceous filament that extends in the cytoplasm of a nerve cell is also termed a
857:
720:
575:
555:
427:
287:
139:
8:
5689:
4322:
3352:
3197:
3192:
2727:
2660:
2100:"Stochastic simulation of neurofilament transport in axons: the "stop-and-go" hypothesis"
1510:
1252:
267:
119:
2562:
2529:
2395:
2304:
2149:"Neurofilament phosphoforms: surrogate markers for axonal injury, degeneration and loss"
1276:
4142:
3772:
3387:
3357:
3288:
3257:
3247:
3242:
3237:
3182:
2958:
2868:
2722:
2510:
2467:
2414:
2379:
2359:
2316:
2272:
2229:
2179:
2124:
2099:
2080:
2032:
2007:
1988:
1940:
1931:
1915:
1871:
1828:
1780:
1755:
1662:
1637:
1613:
1588:
1564:
1539:
1487:
1462:
1441:
1402:
1359:
1260:
1201:
region, known as the rod domain because of its rod-like tertiary structure, flanked by
1008:
1136:
neurofilament triplet proteins contain long stretches of polypeptide sequence rich in
5540:
3904:
3372:
3362:
3347:
3252:
3117:
2898:
2850:
2655:
2650:
2567:
2549:
2502:
2471:
2459:
2419:
2351:
2308:
2264:
2260:
2221:
2171:
2129:
2084:
2072:
2037:
1980:
1945:
1894:
1863:
1820:
1785:
1734:
1727:
1708:
1667:
1618:
1569:
1492:
1392:
There is also considerable clinical interest in the use of neurofilament proteins as
2514:
2363:
2320:
2276:
2233:
2183:
1992:
5488:
4612:
3967:
3962:
3339:
3302:
3297:
2645:
2557:
2541:
2498:
2494:
2451:
2409:
2399:
2343:
2300:
2256:
2213:
2163:
2119:
2111:
2064:
2055:
Brown A (November 2000). "Slow axonal transport: stop and go traffic in the axon".
2027:
2019:
1972:
1935:
1927:
1875:
1859:
1855:
1832:
1812:
1775:
1767:
1698:
1657:
1653:
1649:
1636:
Yuan A, Sasaki T, Kumar A, Peterhoff CM, Rao MV, Liem RK, et al. (June 2012).
1608:
1604:
1600:
1559:
1551:
1482:
1474:
1329:
991:
947:
828:
691:
667:
546:
398:
258:
110:
1587:
Yuan A, Rao MV, Sasaki T, Chen Y, Kumar A, Liem RK, et al. (September 2006).
1328:
In addition to their structural role in axons, neurofilaments are also cargoes of
5630:
4244:
4094:
3977:
3107:
3076:
3071:
2953:
2948:
2772:
2545:
2404:
2347:
1240:
1218:
804:
522:
374:
234:
86:
867:
730:
585:
437:
297:
149:
5593:
5456:
4153:
3984:
3493:
3412:
3397:
3367:
3324:
3144:
3102:
3080:
3000:
2883:
2707:
2612:
2148:
1382:
1371:
1300:
1166:
1144:
residues, and NF-M and especially NF-H also contain multiple tandemly repeated
1128:
2217:
2167:
1366:. Such antibodies are widely used to identify neurons and their processes in
5743:
5657:
5652:
4487:
4436:
4386:
4326:
4248:
4216:
4157:
3943:
3462:
3031:
2712:
2553:
1337:
1248:
1222:
1187:
1137:
903:
2115:
1229:
938:(GFAP). Type IV consists of the neurofilament proteins NF-L, NF-M, NF-H and
910:. They are believed to function primarily to provide structural support for
5501:
4556:
4311:
3855:
3447:
3292:
3214:
3127:
3008:
2938:
2717:
2640:
2571:
2506:
2463:
2423:
2355:
2268:
2225:
2175:
2133:
2076:
2041:
1984:
1867:
1824:
1671:
1622:
1496:
1375:
1292:
1284:
1161:
996:
907:
5473:
5451:
2312:
1949:
1789:
1712:
1687:"Dynamics of neuronal intermediate filaments: a developmental perspective"
5647:
5598:
5468:
5358:
4688:
4132:
4087:
4006:
3928:
3476:
3307:
3122:
3026:
2984:
2916:
2911:
2732:
2670:
2665:
2635:
1703:
1686:
1555:
1333:
1317:
1264:
1256:
1210:
1198:
899:
816:
679:
534:
386:
246:
98:
1573:
5699:
5618:
5608:
5496:
4607:
4586:
4352:
4289:
4284:
4279:
4259:
4234:
4222:
4208:
4203:
4198:
4193:
4188:
4183:
4178:
4173:
4168:
4030:
3912:
3901:
3887:
3503:
3377:
3066:
2943:
2906:
1816:
1478:
1414:
1355:
1308:
1280:
1206:
1202:
1182:
939:
931:
811:
674:
529:
452:
381:
241:
93:
1771:
5528:
5523:
5518:
5478:
5316:
5311:
5306:
4664:
4644:
4299:
4294:
4274:
4269:
4264:
4254:
4163:
4067:
4001:
3392:
2926:
2777:
2750:
2742:
2068:
2023:
1976:
1393:
891:
5642:
5603:
5535:
5508:
5375:
5363:
5238:
5233:
4674:
4669:
4591:
4025:
4020:
3882:
3056:
3041:
3036:
2760:
2755:
2682:
2677:
2378:
Niemelä V, Landtblom AM, Blennow K, Sundblom J (27 February 2017).
1410:
1236:
1233:
1132:
1004:
923:
5669:
5623:
5513:
5443:
5412:
5342:
5337:
5301:
5296:
5291:
5258:
5228:
5223:
5218:
5213:
4898:
4830:
4825:
4820:
4815:
4810:
4702:
4639:
4127:
4072:
4013:
3996:
3957:
3443:
3319:
3280:
3172:
2581:
2246:
951:
922:
which are expressed in epithelia. Type III contains the proteins
919:
895:
2333:
2289:
792:
655:
510:
362:
222:
74:
16:
Type IV intermediate filaments found in the cytoplasm of neurons
5588:
5570:
5565:
5560:
5555:
5545:
5380:
5273:
5268:
5253:
5248:
5160:
5106:
5071:
5046:
5041:
5036:
5031:
5021:
5016:
5006:
4991:
4986:
4868:
4863:
4858:
4770:
4760:
4740:
4725:
4720:
4715:
4710:
4576:
4347:
4342:
4099:
3765:
3760:
3750:
3528:
2979:
2934:
2699:
2377:
1244:
1150:
1145:
1141:
1012:
1000:
950:. The type IV intermediate filament genes all share two unique
927:
799:
662:
517:
369:
229:
81:
1381:
Neurofilament antibodies are also commonly used in diagnostic
5613:
5385:
5368:
5205:
5200:
5190:
5185:
5150:
5140:
5130:
5115:
5096:
5086:
5081:
5066:
5061:
5056:
5051:
5026:
5011:
5001:
4996:
4981:
4976:
4956:
4951:
4946:
4941:
4936:
4931:
4926:
4921:
4916:
4911:
4906:
4878:
4873:
4840:
4835:
4805:
4800:
4780:
4775:
4755:
4745:
4660:
4538:
4533:
4528:
4523:
4518:
4513:
4508:
4503:
4498:
4493:
4477:
4472:
4467:
4462:
4457:
4452:
4447:
4442:
4417:
4412:
4407:
4402:
4397:
4392:
4372:
4367:
4362:
4357:
4337:
4332:
4042:
3972:
3921:
3918:
3915:
3907:
3896:
3893:
3890:
3875:
3870:
3865:
3860:
3832:
3822:
3807:
3740:
3730:
3710:
3685:
3680:
3665:
3655:
3650:
3645:
3640:
3635:
3630:
3615:
3569:
3564:
3559:
3549:
3544:
3539:
3518:
3513:
3508:
3498:
3485:
2006:
Fenn JD, Johnson CM, Peng J, Jung P, Brown A (January 2018).
943:
5714:
5709:
5704:
5664:
5635:
5550:
5427:
5422:
5417:
5321:
4971:
4966:
4961:
4888:
4883:
4750:
4632:
4627:
4622:
4082:
4077:
4035:
3948:
3938:
3933:
3827:
3817:
3812:
3802:
3792:
3787:
3782:
3777:
3700:
3625:
3620:
3610:
3605:
3600:
3595:
3590:
3585:
3018:
1386:
987:
983:
979:
911:
312:
164:
38:
22:
2199:"Neurofilaments as biomarkers in neurological disorders"
2196:
1635:
1181:
A formalin fixed and paraffin embedded section of human
1156:
1153:
one of which produces 44 and the other 45 KSP repeats.
745:
Nestin neuronal stem cell intermediate filament protein
1845:
1461:
Yuan, A; Rao, MV; Veeranna; Nixon, RA (15 July 2012).
1343:
1802:
1460:
2005:
1421:. Recent work performed as a collaboration between
990:). These proteins were discovered from studies of
2527:
1726:
2484:
1586:
1251:. The cells expressing neurofilaments are in the
600:Peripherin neuronal intermediate filament protein
5741:
3442:
1913:
1378:. This protein is lost as development proceeds.
1190:cells and various othe axons. Image courtesy of
914:and to regulate axon diameter, which influences
2444:Journal of Stroke and Cerebrovascular Diseases
2437:
3428:
2597:
2097:
1962:
1753:
167:medium molecular weight neurofilament protein
2478:
1537:
1413:mice with neurofilament abnormalities have
315:high molecular weight neurofilament protein
3435:
3421:
2604:
2590:
2521:
2456:10.1016/j.jstrokecerebrovasdis.2020.104813
2098:Brown A, Wang L, Jung P (September 2005).
1914:Black MM, Keyser P, Sobel E (April 1986).
1323:
25:low molecular weight neurofilament protein
2561:
2413:
2403:
2123:
2031:
1939:
1779:
1702:
1684:
1661:
1612:
1563:
1486:
1271:
972:
1275:
1228:
1176:
1160:
2146:
1888:
1733:(4th ed.). Garland Science. 2002.
1389:(negative for neurofilament proteins).
5742:
2057:Nature Reviews. Molecular Cell Biology
946:, and type VI consists of the protein
455:neuronal intermediate filament protein
3416:
2585:
2054:
1019:Human neurofilament subunit proteins
2156:Journal of the Neurological Sciences
1538:Hoffman PN, Lasek RJ (August 1975).
1533:
1531:
1157:Neurofilament assembly and structure
906:(7 nm), they form the neuronal
2305:10.1046/j.1471-4159.1996.67052013.x
1882:
1454:
1036:Apparent molecular mass (SDS-PAGE)
986:) and NF-H (high molecular weight;
13:
2611:
1932:10.1523/JNEUROSCI.06-04-01004.1986
1754:Eyer J, Leterrier JF (June 1988).
1691:Cell Motility and the Cytoskeleton
1344:Clinical and research applications
1239:against neurofilament (green) and
982:), NF-M (medium molecular weight;
14:
5786:
1528:
1503:
4063:Wiskott–Aldrich syndrome protein
2261:10.1111/j.1468-1331.2009.02808.x
1289:anterior horn of the spinal cord
5284:Microtubule organising proteins
2768:Oligodendrocyte progenitor cell
2431:
2371:
2327:
2283:
2240:
2190:
2140:
2091:
2048:
1999:
1956:
1907:
1893:(Sixth ed.). p. 947.
1839:
936:glial fibrillary acidic protein
2499:10.1515/REVNEURO.2003.14.4.369
1860:10.1016/j.brainres.2010.01.075
1796:
1747:
1719:
1678:
1654:10.1523/jneurosci.1081-12.2012
1629:
1605:10.1523/jneurosci.2580-06.2006
1580:
1336:tracks powered by microtubule
1131:of each protein determined by
888:type IV intermediate filaments
1:
5331:Microtubule severing proteins
2249:European Journal of Neurology
2104:Molecular Biology of the Cell
1891:Molecular biology of the cell
1729:Molecular biology of the cell
1447:
1419:amyotrophic lateral sclerosis
1399:amyotrophic lateral sclerosis
5765:Genes on human chromosome 12
5760:Genes on human chromosome 10
5755:Genes on human chromosome 22
3991:actin depolymerizing factors
2487:Reviews in the Neurosciences
2405:10.1371/journal.pone.0172762
2348:10.1212/wnl.0b013e3181a0fe3f
1463:"Neurofilaments at a glance"
1307:Neurofilaments are found in
7:
5770:Genes on human chromosome 1
5750:Genes on human chromosome 8
5469:Plakoglobin (gamma catenin)
2878:Postganglionic nerve fibers
1920:The Journal of Neuroscience
1642:The Journal of Neuroscience
1593:The Journal of Neuroscience
1544:The Journal of Cell Biology
1511:"Definition of Neurofibril"
1435:
961:. This name is used in the
10:
5791:
2873:Preganglionic nerve fibers
2546:10.1093/braincomms/fcad067
1685:Nixon RA, Shea TB (1992).
1347:
1287:(bottom of image) and the
967:neurodegenerative diseases
5725:
5682:
5581:
5487:
5442:
5351:
5330:
5282:
5105:
4897:
4849:
4701:
4687:
4653:
4600:
4569:
4549:
4428:
4310:
4141:
4123:
4112:
4055:
3848:
3527:
3484:
3475:
3461:
3454:
3383:Olfactory receptor neuron
3338:
3279:
3272:
3208:
3138:
3095:
3055:
3047:Neurofibril/neurofilament
3017:
2999:
2992:
2978:
2925:
2897:
2803:
2794:
2741:
2698:
2691:
2628:
2619:
2293:Journal of Neurochemistry
2218:10.1038/s41582-018-0058-z
2206:Nature Reviews. Neurology
2168:10.1016/j.jns.2005.03.015
1165:Rat brain cells grown in
1033:Predicted molecular mass
999:that is expressed in the
942:. Type V consists of the
916:nerve conduction velocity
863:
853:
848:
844:
827:
822:
810:
798:
786:
774:
762:
754:
749:
744:
726:
716:
711:
707:
690:
685:
673:
661:
649:
637:
625:
617:
609:
604:
599:
581:
571:
566:
562:
545:
540:
528:
516:
504:
492:
480:
472:
464:
459:
451:
433:
423:
418:
414:
397:
392:
380:
368:
356:
344:
332:
324:
319:
311:
293:
283:
278:
274:
257:
252:
240:
228:
216:
204:
192:
184:
176:
171:
163:
145:
135:
130:
126:
109:
104:
92:
80:
68:
56:
44:
34:
29:
21:
5695:Prokaryotic cytoskeleton
1423:EnCor Biotechnology Inc.
1192:EnCor Biotechnology Inc.
1172:EnCor Biotechnology Inc.
1109:Neurofilament protein H
1092:Neurofilament protein M
1075:Neurofilament protein L
2147:Petzold A (June 2005).
2116:10.1091/mbc.E05-02-0141
1805:Journal of Cell Science
1760:The Biochemical Journal
1515:www.merriam-webster.com
1467:Journal of Cell Science
1324:Neurofilament transport
963:neurofibrillary tangles
3330:Neuromuscular junction
3193:III or Aδ or fast pain
1350:Neurofibrillary tangle
1304:
1272:Neurofilament function
1268:
1194:
1174:
973:Neurofilament proteins
4315:(hard alpha-keratins)
4146:(soft alpha-keratins)
1427:University of Florida
1368:histological sections
1348:Further information:
1297:central chromatolysis
1279:
1255:shown in green while
1232:
1180:
1164:
5730:cytoskeletal defects
5690:Major sperm proteins
3348:Meissner's corpuscle
3313:Postsynaptic density
3210:Efferent nerve fiber
3198:IV or C or slow pain
3140:Afferent nerve fiber
2966:Satellite glial cell
2534:Brain Communications
1704:10.1002/cm.970220202
1556:10.1083/jcb.66.2.351
1407:Huntington's disease
1405:, and more recently
1364:immunohistochemistry
4143:Epithelial keratins
3353:Merkel nerve ending
2396:2017PLoSO..1272762N
1965:Nature Cell Biology
1889:Alberts, D (2015).
1257:proliferating cells
1253:dorsal root ganglia
1020:
3388:Photoreceptor cell
3358:Pacinian corpuscle
3289:Electrical synapse
3243:Lower motor neuron
3238:Upper motor neuron
2959:Internodal segment
2899:Connective tissues
2869:Autonomic ganglion
1817:10.1242/jcs.051318
1811:(Pt 19): 3579–86.
1479:10.1242/jcs.104729
1473:(Pt 14): 3257–63.
1442:Bielschowsky stain
1403:multiple sclerosis
1360:immunofluorescence
1354:Numerous specific
1305:
1269:
1195:
1175:
1018:
1009:horizontal neurons
902:(~25 nm) and
5737:
5736:
5678:
5677:
5438:
5437:
4683:
4682:
4565:
4564:
4108:
4107:
4051:
4050:
3410:
3409:
3406:
3405:
3373:Free nerve ending
3340:Sensory receptors
3268:
3267:
3183:Ib or Golgi or Aα
3091:
3090:
2974:
2973:
2851:Ramus communicans
2790:
2789:
2786:
2785:
2656:Commissural fiber
2651:Association fiber
2646:Projection fibers
1772:10.1042/bj2520655
1740:978-0-8153-3218-3
1243:(red) in a mouse
1125:
1124:
886:) are classed as
877:
876:
873:
872:
740:
739:
736:
735:
595:
594:
591:
590:
447:
446:
443:
442:
307:
306:
303:
302:
159:
158:
155:
154:
5782:
4699:
4698:
4139:
4138:
4121:
4120:
3482:
3481:
3473:
3472:
3459:
3458:
3437:
3430:
3423:
3414:
3413:
3303:Synaptic vesicle
3298:Chemical synapse
3277:
3276:
2997:
2996:
2990:
2989:
2801:
2800:
2696:
2695:
2626:
2625:
2606:
2599:
2592:
2583:
2582:
2576:
2575:
2565:
2525:
2519:
2518:
2482:
2476:
2475:
2435:
2429:
2427:
2417:
2407:
2375:
2369:
2367:
2331:
2325:
2324:
2287:
2281:
2280:
2244:
2238:
2237:
2203:
2194:
2188:
2187:
2153:
2144:
2138:
2137:
2127:
2095:
2089:
2088:
2069:10.1038/35040102
2052:
2046:
2045:
2035:
2024:10.1002/cm.21411
2003:
1997:
1996:
1977:10.1038/35004008
1960:
1954:
1953:
1943:
1911:
1905:
1904:
1886:
1880:
1879:
1843:
1837:
1836:
1800:
1794:
1793:
1783:
1751:
1745:
1744:
1732:
1723:
1717:
1716:
1706:
1682:
1676:
1675:
1665:
1633:
1627:
1626:
1616:
1599:(39): 10006–19.
1584:
1578:
1577:
1567:
1535:
1526:
1525:
1523:
1521:
1507:
1501:
1500:
1490:
1458:
1330:axonal transport
1267:and colored red.
1261:ventricular zone
1247:12.5 days after
1207:carboxy terminal
1021:
1017:
992:axonal transport
846:
845:
742:
741:
709:
708:
597:
596:
564:
563:
453:Alpha-internexin
449:
448:
416:
415:
309:
308:
276:
275:
161:
160:
128:
127:
19:
18:
5790:
5789:
5785:
5784:
5783:
5781:
5780:
5779:
5740:
5739:
5738:
5733:
5721:
5674:
5577:
5483:
5434:
5347:
5326:
5278:
5101:
4893:
4845:
4691:
4679:
4649:
4596:
4561:
4545:
4429:Ungrouped alpha
4424:
4314:
4306:
4145:
4131:
4125:
4115:
4104:
4047:
3844:
3523:
3465:
3450:
3441:
3411:
3402:
3334:
3264:
3213:
3204:
3188:II or Aβ and Aγ
3143:
3134:
3087:
3077:Apical dendrite
3072:Dendritic spine
3051:
3013:
2983:
2970:
2954:Node of Ranvier
2949:Myelin incisure
2921:
2893:
2782:
2773:Oligodendrocyte
2756:Ependymal cells
2737:
2687:
2615:
2610:
2580:
2579:
2526:
2522:
2483:
2479:
2436:
2432:
2390:(2): e0172762.
2376:
2372:
2332:
2328:
2288:
2284:
2245:
2241:
2212:(10): 577–589.
2201:
2195:
2191:
2162:(1–2): 183–98.
2151:
2145:
2141:
2096:
2092:
2053:
2049:
2004:
2000:
1961:
1957:
1912:
1908:
1901:
1887:
1883:
1844:
1840:
1801:
1797:
1752:
1748:
1741:
1725:
1724:
1720:
1683:
1679:
1634:
1630:
1585:
1581:
1536:
1529:
1519:
1517:
1509:
1508:
1504:
1459:
1455:
1450:
1438:
1432:
1352:
1346:
1326:
1299:.Neurofilament
1274:
1219:phosphorylation
1159:
975:
17:
12:
11:
5:
5788:
5778:
5777:
5772:
5767:
5762:
5757:
5752:
5735:
5734:
5726:
5723:
5722:
5720:
5719:
5718:
5717:
5712:
5707:
5702:
5692:
5686:
5684:
5680:
5679:
5676:
5675:
5673:
5672:
5667:
5662:
5661:
5660:
5655:
5645:
5640:
5639:
5638:
5628:
5627:
5626:
5621:
5616:
5611:
5606:
5601:
5596:
5594:Corneodesmosin
5585:
5583:
5579:
5578:
5576:
5575:
5574:
5573:
5568:
5563:
5558:
5553:
5548:
5543:
5533:
5532:
5531:
5526:
5521:
5511:
5506:
5505:
5504:
5493:
5491:
5485:
5484:
5482:
5481:
5476:
5471:
5466:
5465:
5464:
5454:
5448:
5446:
5440:
5439:
5436:
5435:
5433:
5432:
5431:
5430:
5425:
5420:
5410:
5409:
5408:
5403:
5398:
5393:
5388:
5378:
5373:
5372:
5371:
5361:
5355:
5353:
5349:
5348:
5346:
5345:
5340:
5334:
5332:
5328:
5327:
5325:
5324:
5319:
5314:
5309:
5304:
5299:
5294:
5288:
5286:
5280:
5279:
5277:
5276:
5271:
5266:
5261:
5256:
5251:
5246:
5241:
5236:
5231:
5226:
5221:
5216:
5209:
5208:
5203:
5198:
5193:
5188:
5183:
5178:
5173:
5168:
5163:
5158:
5153:
5148:
5143:
5138:
5133:
5128:
5123:
5118:
5111:
5109:
5103:
5102:
5100:
5099:
5094:
5089:
5084:
5079:
5074:
5069:
5064:
5059:
5054:
5049:
5044:
5039:
5034:
5029:
5024:
5019:
5014:
5009:
5004:
4999:
4994:
4989:
4984:
4979:
4974:
4969:
4964:
4959:
4954:
4949:
4944:
4939:
4934:
4929:
4924:
4919:
4914:
4909:
4903:
4901:
4895:
4894:
4892:
4891:
4886:
4881:
4876:
4871:
4866:
4861:
4855:
4853:
4847:
4846:
4844:
4843:
4838:
4833:
4828:
4823:
4818:
4813:
4808:
4803:
4798:
4793:
4788:
4783:
4778:
4773:
4768:
4763:
4758:
4753:
4748:
4743:
4738:
4733:
4728:
4723:
4718:
4713:
4707:
4705:
4696:
4685:
4684:
4681:
4680:
4678:
4677:
4672:
4667:
4661:Nuclear lamins
4657:
4655:
4651:
4650:
4648:
4647:
4642:
4637:
4636:
4635:
4630:
4625:
4615:
4610:
4604:
4602:
4598:
4597:
4595:
4594:
4589:
4584:
4579:
4573:
4571:
4567:
4566:
4563:
4562:
4560:
4559:
4553:
4551:
4547:
4546:
4544:
4543:
4542:
4541:
4536:
4531:
4526:
4521:
4516:
4511:
4506:
4501:
4496:
4483:
4482:
4481:
4480:
4475:
4470:
4465:
4460:
4455:
4450:
4445:
4432:
4430:
4426:
4425:
4423:
4422:
4421:
4420:
4415:
4410:
4405:
4400:
4395:
4378:
4377:
4376:
4375:
4370:
4365:
4360:
4355:
4350:
4345:
4340:
4335:
4318:
4316:
4308:
4307:
4305:
4304:
4303:
4302:
4297:
4292:
4287:
4282:
4277:
4272:
4267:
4262:
4257:
4240:
4239:
4238:
4237:
4227:
4226:
4225:
4213:
4212:
4211:
4206:
4201:
4196:
4191:
4186:
4181:
4176:
4171:
4166:
4149:
4147:
4136:
4118:
4110:
4109:
4106:
4105:
4103:
4102:
4097:
4092:
4091:
4090:
4085:
4080:
4070:
4065:
4059:
4057:
4053:
4052:
4049:
4048:
4046:
4045:
4040:
4039:
4038:
4033:
4023:
4018:
4017:
4016:
4011:
4010:
4009:
4004:
3987:
3985:Arp2/3 complex
3982:
3981:
3980:
3975:
3970:
3965:
3954:
3953:
3952:
3951:
3946:
3941:
3936:
3926:
3925:
3924:
3910:
3899:
3880:
3879:
3878:
3873:
3868:
3863:
3852:
3850:
3846:
3845:
3843:
3842:
3841:
3840:
3835:
3830:
3825:
3820:
3815:
3810:
3805:
3800:
3795:
3790:
3785:
3780:
3770:
3769:
3768:
3763:
3755:
3754:
3753:
3745:
3744:
3743:
3735:
3734:
3733:
3728:
3720:
3719:
3718:
3713:
3705:
3704:
3703:
3695:
3694:
3693:
3688:
3683:
3675:
3674:
3673:
3668:
3660:
3659:
3658:
3653:
3648:
3643:
3638:
3633:
3628:
3623:
3618:
3613:
3608:
3603:
3598:
3593:
3588:
3580:
3579:
3578:
3572:
3567:
3562:
3557:
3552:
3547:
3542:
3533:
3531:
3525:
3524:
3522:
3521:
3516:
3511:
3506:
3501:
3496:
3490:
3488:
3479:
3470:
3463:Microfilaments
3456:
3452:
3451:
3440:
3439:
3432:
3425:
3417:
3408:
3407:
3404:
3403:
3401:
3400:
3398:Taste receptor
3395:
3390:
3385:
3380:
3375:
3370:
3368:Muscle spindle
3365:
3363:Ruffini ending
3360:
3355:
3350:
3344:
3342:
3336:
3335:
3333:
3332:
3327:
3325:Ribbon synapse
3322:
3317:
3316:
3315:
3310:
3305:
3295:
3285:
3283:
3274:
3270:
3269:
3266:
3265:
3263:
3262:
3261:
3260:
3255:
3250:
3240:
3235:
3230:
3225:
3219:
3217:
3206:
3205:
3203:
3202:
3201:
3200:
3195:
3190:
3185:
3180:
3170:
3165:
3160:
3155:
3149:
3147:
3145:Sensory neuron
3136:
3135:
3133:
3132:
3131:
3130:
3120:
3115:
3113:Pseudounipolar
3110:
3105:
3099:
3097:
3093:
3092:
3089:
3088:
3086:
3085:
3084:
3083:
3081:Basal dendrite
3074:
3069:
3061:
3059:
3053:
3052:
3050:
3049:
3044:
3039:
3034:
3032:Axon terminals
3029:
3023:
3021:
3015:
3014:
3012:
3011:
3005:
3003:
2994:
2987:
2976:
2975:
2972:
2971:
2969:
2968:
2963:
2962:
2961:
2956:
2951:
2946:
2931:
2929:
2923:
2922:
2920:
2919:
2914:
2909:
2903:
2901:
2895:
2894:
2892:
2891:
2886:
2884:Nerve fascicle
2881:
2875:
2866:
2865:
2864:
2859:
2847:
2846:
2845:
2840:
2830:
2829:
2828:
2823:
2818:
2807:
2805:
2798:
2792:
2791:
2788:
2787:
2784:
2783:
2781:
2780:
2775:
2770:
2765:
2764:
2763:
2753:
2747:
2745:
2739:
2738:
2736:
2735:
2730:
2725:
2720:
2715:
2710:
2704:
2702:
2693:
2689:
2688:
2686:
2685:
2680:
2675:
2674:
2673:
2668:
2663:
2658:
2653:
2648:
2638:
2632:
2630:
2623:
2617:
2616:
2613:Nervous tissue
2609:
2608:
2601:
2594:
2586:
2578:
2577:
2520:
2477:
2430:
2370:
2342:(15): 1322–9.
2326:
2282:
2239:
2189:
2139:
2110:(9): 4243–55.
2090:
2047:
1998:
1955:
1926:(4): 1004–12.
1906:
1899:
1881:
1848:Brain Research
1838:
1795:
1746:
1739:
1718:
1677:
1648:(25): 8501–8.
1628:
1579:
1527:
1502:
1452:
1451:
1449:
1446:
1445:
1444:
1437:
1434:
1383:neuropathology
1372:tissue culture
1362:microscopy or
1345:
1342:
1338:motor proteins
1325:
1322:
1273:
1270:
1203:amino terminal
1167:tissue culture
1158:
1155:
1129:molecular mass
1123:
1122:
1119:
1116:
1113:
1110:
1106:
1105:
1102:
1099:
1096:
1093:
1089:
1088:
1085:
1082:
1079:
1076:
1072:
1071:
1068:
1065:
1062:
1059:
1055:
1054:
1051:
1048:
1045:
1042:
1038:
1037:
1034:
1031:
1028:
1025:
974:
971:
944:nuclear lamins
904:microfilaments
880:Neurofilaments
875:
874:
871:
870:
865:
861:
860:
855:
851:
850:
842:
841:
831:
825:
824:
820:
819:
814:
808:
807:
802:
796:
795:
790:
784:
783:
778:
772:
771:
766:
760:
759:
756:
752:
751:
747:
746:
738:
737:
734:
733:
728:
724:
723:
718:
714:
713:
705:
704:
694:
688:
687:
683:
682:
677:
671:
670:
665:
659:
658:
653:
647:
646:
641:
635:
634:
629:
623:
622:
619:
615:
614:
611:
607:
606:
602:
601:
593:
592:
589:
588:
583:
579:
578:
573:
569:
568:
560:
559:
549:
543:
542:
538:
537:
532:
526:
525:
520:
514:
513:
508:
502:
501:
496:
490:
489:
484:
478:
477:
474:
470:
469:
466:
462:
461:
457:
456:
445:
444:
441:
440:
435:
431:
430:
425:
421:
420:
412:
411:
401:
395:
394:
390:
389:
384:
378:
377:
372:
366:
365:
360:
354:
353:
348:
342:
341:
336:
330:
329:
326:
322:
321:
317:
316:
305:
304:
301:
300:
295:
291:
290:
285:
281:
280:
272:
271:
261:
255:
254:
250:
249:
244:
238:
237:
232:
226:
225:
220:
214:
213:
208:
202:
201:
196:
190:
189:
186:
182:
181:
178:
174:
173:
169:
168:
157:
156:
153:
152:
147:
143:
142:
137:
133:
132:
124:
123:
113:
107:
106:
102:
101:
96:
90:
89:
84:
78:
77:
72:
66:
65:
60:
54:
53:
48:
42:
41:
36:
32:
31:
27:
26:
15:
9:
6:
4:
3:
2:
5787:
5776:
5773:
5771:
5768:
5766:
5763:
5761:
5758:
5756:
5753:
5751:
5748:
5747:
5745:
5732:
5731:
5724:
5716:
5713:
5711:
5708:
5706:
5703:
5701:
5698:
5697:
5696:
5693:
5691:
5688:
5687:
5685:
5681:
5671:
5668:
5666:
5663:
5659:
5656:
5654:
5651:
5650:
5649:
5646:
5644:
5641:
5637:
5634:
5633:
5632:
5629:
5625:
5622:
5620:
5617:
5615:
5612:
5610:
5607:
5605:
5602:
5600:
5597:
5595:
5592:
5591:
5590:
5587:
5586:
5584:
5580:
5572:
5569:
5567:
5564:
5562:
5559:
5557:
5554:
5552:
5549:
5547:
5544:
5542:
5539:
5538:
5537:
5534:
5530:
5527:
5525:
5522:
5520:
5517:
5516:
5515:
5512:
5510:
5507:
5503:
5500:
5499:
5498:
5495:
5494:
5492:
5490:
5486:
5480:
5477:
5475:
5474:Delta catenin
5472:
5470:
5467:
5463:
5460:
5459:
5458:
5455:
5453:
5452:Alpha catenin
5450:
5449:
5447:
5445:
5441:
5429:
5426:
5424:
5421:
5419:
5416:
5415:
5414:
5411:
5407:
5404:
5402:
5399:
5397:
5394:
5392:
5389:
5387:
5384:
5383:
5382:
5379:
5377:
5374:
5370:
5367:
5366:
5365:
5362:
5360:
5357:
5356:
5354:
5350:
5344:
5341:
5339:
5336:
5335:
5333:
5329:
5323:
5320:
5318:
5315:
5313:
5310:
5308:
5305:
5303:
5300:
5298:
5295:
5293:
5290:
5289:
5287:
5285:
5281:
5275:
5272:
5270:
5267:
5265:
5262:
5260:
5257:
5255:
5252:
5250:
5247:
5245:
5242:
5240:
5237:
5235:
5232:
5230:
5227:
5225:
5222:
5220:
5217:
5215:
5212:cytoplasmic:
5211:
5210:
5207:
5204:
5202:
5199:
5197:
5194:
5192:
5189:
5187:
5184:
5182:
5179:
5177:
5174:
5172:
5169:
5167:
5164:
5162:
5159:
5157:
5154:
5152:
5149:
5147:
5144:
5142:
5139:
5137:
5134:
5132:
5129:
5127:
5124:
5122:
5119:
5117:
5113:
5112:
5110:
5108:
5104:
5098:
5095:
5093:
5090:
5088:
5085:
5083:
5080:
5078:
5075:
5073:
5070:
5068:
5065:
5063:
5060:
5058:
5055:
5053:
5050:
5048:
5045:
5043:
5040:
5038:
5035:
5033:
5030:
5028:
5025:
5023:
5020:
5018:
5015:
5013:
5010:
5008:
5005:
5003:
5000:
4998:
4995:
4993:
4990:
4988:
4985:
4983:
4980:
4978:
4975:
4973:
4970:
4968:
4965:
4963:
4960:
4958:
4955:
4953:
4950:
4948:
4945:
4943:
4940:
4938:
4935:
4933:
4930:
4928:
4925:
4923:
4920:
4918:
4915:
4913:
4910:
4908:
4905:
4904:
4902:
4900:
4896:
4890:
4887:
4885:
4882:
4880:
4877:
4875:
4872:
4870:
4867:
4865:
4862:
4860:
4857:
4856:
4854:
4852:
4848:
4842:
4839:
4837:
4834:
4832:
4829:
4827:
4824:
4822:
4819:
4817:
4814:
4812:
4809:
4807:
4804:
4802:
4799:
4797:
4794:
4792:
4789:
4787:
4784:
4782:
4779:
4777:
4774:
4772:
4769:
4767:
4764:
4762:
4759:
4757:
4754:
4752:
4749:
4747:
4744:
4742:
4739:
4737:
4734:
4732:
4729:
4727:
4724:
4722:
4719:
4717:
4714:
4712:
4709:
4708:
4706:
4704:
4700:
4697:
4695:
4690:
4686:
4676:
4673:
4671:
4668:
4666:
4662:
4659:
4658:
4656:
4652:
4646:
4643:
4641:
4638:
4634:
4631:
4629:
4626:
4624:
4621:
4620:
4619:
4618:Neurofilament
4616:
4614:
4611:
4609:
4606:
4605:
4603:
4599:
4593:
4590:
4588:
4585:
4583:
4580:
4578:
4575:
4574:
4572:
4568:
4558:
4555:
4554:
4552:
4548:
4540:
4537:
4535:
4532:
4530:
4527:
4525:
4522:
4520:
4517:
4515:
4512:
4510:
4507:
4505:
4502:
4500:
4497:
4495:
4492:
4491:
4490:
4489:
4488:chromosome 12
4485:
4484:
4479:
4476:
4474:
4471:
4469:
4466:
4464:
4461:
4459:
4456:
4454:
4451:
4449:
4446:
4444:
4441:
4440:
4439:
4438:
4437:chromosome 17
4434:
4433:
4431:
4427:
4419:
4416:
4414:
4411:
4409:
4406:
4404:
4401:
4399:
4396:
4394:
4391:
4390:
4389:
4388:
4387:chromosome 12
4384:
4380:
4379:
4374:
4371:
4369:
4366:
4364:
4361:
4359:
4356:
4354:
4351:
4349:
4346:
4344:
4341:
4339:
4336:
4334:
4331:
4330:
4329:
4328:
4327:chromosome 17
4324:
4320:
4319:
4317:
4313:
4312:Hair keratins
4309:
4301:
4298:
4296:
4293:
4291:
4288:
4286:
4283:
4281:
4278:
4276:
4273:
4271:
4268:
4266:
4263:
4261:
4258:
4256:
4253:
4252:
4251:
4250:
4249:chromosome 12
4246:
4242:
4241:
4236:
4233:
4232:
4231:
4228:
4224:
4221:
4220:
4219:
4218:
4217:chromosome 12
4214:
4210:
4207:
4205:
4202:
4200:
4197:
4195:
4192:
4190:
4187:
4185:
4182:
4180:
4177:
4175:
4172:
4170:
4167:
4165:
4162:
4161:
4160:
4159:
4158:chromosome 17
4155:
4151:
4150:
4148:
4144:
4140:
4137:
4134:
4129:
4122:
4119:
4117:
4114:Intermediate
4111:
4101:
4098:
4096:
4093:
4089:
4086:
4084:
4081:
4079:
4076:
4075:
4074:
4071:
4069:
4066:
4064:
4061:
4060:
4058:
4054:
4044:
4041:
4037:
4034:
4032:
4029:
4028:
4027:
4024:
4022:
4019:
4015:
4012:
4008:
4005:
4003:
4000:
3999:
3998:
3995:
3994:
3993:
3992:
3988:
3986:
3983:
3979:
3976:
3974:
3971:
3969:
3966:
3964:
3961:
3960:
3959:
3956:
3955:
3950:
3947:
3945:
3942:
3940:
3937:
3935:
3932:
3931:
3930:
3927:
3923:
3920:
3917:
3914:
3911:
3909:
3906:
3903:
3900:
3898:
3895:
3892:
3889:
3886:
3885:
3884:
3881:
3877:
3874:
3872:
3869:
3867:
3864:
3862:
3859:
3858:
3857:
3854:
3853:
3851:
3847:
3839:
3836:
3834:
3831:
3829:
3826:
3824:
3821:
3819:
3816:
3814:
3811:
3809:
3806:
3804:
3801:
3799:
3796:
3794:
3791:
3789:
3786:
3784:
3781:
3779:
3776:
3775:
3774:
3771:
3767:
3764:
3762:
3759:
3758:
3756:
3752:
3749:
3748:
3746:
3742:
3739:
3738:
3736:
3732:
3729:
3727:
3724:
3723:
3721:
3717:
3714:
3712:
3709:
3708:
3706:
3702:
3699:
3698:
3696:
3692:
3689:
3687:
3684:
3682:
3679:
3678:
3676:
3672:
3669:
3667:
3664:
3663:
3661:
3657:
3654:
3652:
3649:
3647:
3644:
3642:
3639:
3637:
3634:
3632:
3629:
3627:
3624:
3622:
3619:
3617:
3614:
3612:
3609:
3607:
3604:
3602:
3599:
3597:
3594:
3592:
3589:
3587:
3584:
3583:
3581:
3576:
3573:
3571:
3568:
3566:
3563:
3561:
3558:
3556:
3553:
3551:
3548:
3546:
3543:
3541:
3538:
3537:
3535:
3534:
3532:
3530:
3526:
3520:
3517:
3515:
3512:
3510:
3507:
3505:
3502:
3500:
3497:
3495:
3492:
3491:
3489:
3487:
3483:
3480:
3478:
3474:
3471:
3469:
3464:
3460:
3457:
3453:
3449:
3445:
3438:
3433:
3431:
3426:
3424:
3419:
3418:
3415:
3399:
3396:
3394:
3391:
3389:
3386:
3384:
3381:
3379:
3376:
3374:
3371:
3369:
3366:
3364:
3361:
3359:
3356:
3354:
3351:
3349:
3346:
3345:
3343:
3341:
3337:
3331:
3328:
3326:
3323:
3321:
3318:
3314:
3311:
3309:
3306:
3304:
3301:
3300:
3299:
3296:
3294:
3290:
3287:
3286:
3284:
3282:
3278:
3275:
3271:
3259:
3258:γ motorneuron
3256:
3254:
3253:β motorneuron
3251:
3249:
3248:α motorneuron
3246:
3245:
3244:
3241:
3239:
3236:
3234:
3231:
3229:
3226:
3224:
3221:
3220:
3218:
3216:
3211:
3207:
3199:
3196:
3194:
3191:
3189:
3186:
3184:
3181:
3179:
3176:
3175:
3174:
3171:
3169:
3166:
3164:
3161:
3159:
3156:
3154:
3151:
3150:
3148:
3146:
3141:
3137:
3129:
3126:
3125:
3124:
3121:
3119:
3116:
3114:
3111:
3109:
3106:
3104:
3101:
3100:
3098:
3094:
3082:
3078:
3075:
3073:
3070:
3068:
3065:
3064:
3063:
3062:
3060:
3058:
3054:
3048:
3045:
3043:
3040:
3038:
3035:
3033:
3030:
3028:
3025:
3024:
3022:
3020:
3016:
3010:
3007:
3006:
3004:
3002:
2998:
2995:
2991:
2988:
2986:
2981:
2977:
2967:
2964:
2960:
2957:
2955:
2952:
2950:
2947:
2945:
2942:
2941:
2940:
2936:
2933:
2932:
2930:
2928:
2924:
2918:
2915:
2913:
2910:
2908:
2905:
2904:
2902:
2900:
2896:
2890:
2887:
2885:
2882:
2879:
2876:
2874:
2870:
2867:
2863:
2860:
2858:
2855:
2854:
2853:
2852:
2848:
2844:
2841:
2839:
2836:
2835:
2834:
2831:
2827:
2824:
2822:
2819:
2817:
2814:
2813:
2812:
2809:
2808:
2806:
2802:
2799:
2797:
2793:
2779:
2776:
2774:
2771:
2769:
2766:
2762:
2759:
2758:
2757:
2754:
2752:
2749:
2748:
2746:
2744:
2740:
2734:
2731:
2729:
2726:
2724:
2721:
2719:
2716:
2714:
2711:
2709:
2706:
2705:
2703:
2701:
2697:
2694:
2690:
2684:
2681:
2679:
2676:
2672:
2669:
2667:
2664:
2662:
2659:
2657:
2654:
2652:
2649:
2647:
2644:
2643:
2642:
2639:
2637:
2634:
2633:
2631:
2627:
2624:
2622:
2618:
2614:
2607:
2602:
2600:
2595:
2593:
2588:
2587:
2584:
2573:
2569:
2564:
2559:
2555:
2551:
2547:
2543:
2539:
2535:
2531:
2524:
2516:
2512:
2508:
2504:
2500:
2496:
2493:(4): 369–85.
2492:
2488:
2481:
2473:
2469:
2465:
2461:
2457:
2453:
2450:(6): 104813.
2449:
2445:
2441:
2434:
2425:
2421:
2416:
2411:
2406:
2401:
2397:
2393:
2389:
2385:
2381:
2374:
2365:
2361:
2357:
2353:
2349:
2345:
2341:
2337:
2330:
2322:
2318:
2314:
2310:
2306:
2302:
2299:(5): 2013–8.
2298:
2294:
2286:
2278:
2274:
2270:
2266:
2262:
2258:
2255:(3): 377–82.
2254:
2250:
2243:
2235:
2231:
2227:
2223:
2219:
2215:
2211:
2207:
2200:
2193:
2185:
2181:
2177:
2173:
2169:
2165:
2161:
2157:
2150:
2143:
2135:
2131:
2126:
2121:
2117:
2113:
2109:
2105:
2101:
2094:
2086:
2082:
2078:
2074:
2070:
2066:
2062:
2058:
2051:
2043:
2039:
2034:
2029:
2025:
2021:
2017:
2013:
2009:
2002:
1994:
1990:
1986:
1982:
1978:
1974:
1971:(3): 137–41.
1970:
1966:
1959:
1951:
1947:
1942:
1937:
1933:
1929:
1925:
1921:
1917:
1910:
1902:
1900:9780815344643
1896:
1892:
1885:
1877:
1873:
1869:
1865:
1861:
1857:
1853:
1849:
1842:
1834:
1830:
1826:
1822:
1818:
1814:
1810:
1806:
1799:
1791:
1787:
1782:
1777:
1773:
1769:
1766:(3): 655–60.
1765:
1761:
1757:
1750:
1742:
1736:
1731:
1730:
1722:
1714:
1710:
1705:
1700:
1696:
1692:
1688:
1681:
1673:
1669:
1664:
1659:
1655:
1651:
1647:
1643:
1639:
1632:
1624:
1620:
1615:
1610:
1606:
1602:
1598:
1594:
1590:
1583:
1575:
1571:
1566:
1561:
1557:
1553:
1550:(2): 351–66.
1549:
1545:
1541:
1534:
1532:
1516:
1512:
1506:
1498:
1494:
1489:
1484:
1480:
1476:
1472:
1468:
1464:
1457:
1453:
1443:
1440:
1439:
1433:
1430:
1428:
1424:
1420:
1416:
1412:
1408:
1404:
1400:
1395:
1390:
1388:
1384:
1379:
1377:
1373:
1369:
1365:
1361:
1357:
1351:
1341:
1339:
1335:
1331:
1321:
1319:
1313:
1310:
1302:
1298:
1294:
1293:motor neurons
1290:
1286:
1282:
1278:
1266:
1262:
1258:
1254:
1250:
1249:fertilization
1246:
1242:
1238:
1235:
1231:
1227:
1224:
1223:glycosylation
1220:
1214:
1212:
1208:
1204:
1200:
1199:alpha helical
1193:
1189:
1184:
1179:
1173:
1168:
1163:
1154:
1152:
1147:
1143:
1139:
1138:glutamic acid
1134:
1130:
1120:
1117:
1114:
1111:
1108:
1107:
1103:
1100:
1097:
1094:
1091:
1090:
1086:
1083:
1080:
1077:
1074:
1073:
1069:
1066:
1063:
1060:
1058:α-Internexin
1057:
1056:
1052:
1049:
1046:
1043:
1040:
1039:
1035:
1032:
1030:NCBI Ref Seq
1029:
1026:
1023:
1022:
1016:
1014:
1010:
1006:
1002:
998:
993:
989:
985:
981:
970:
968:
964:
960:
955:
953:
949:
945:
941:
937:
933:
929:
925:
921:
917:
913:
909:
905:
901:
897:
893:
890:found in the
889:
885:
881:
869:
866:
862:
859:
856:
852:
847:
843:
840:
839:
835:
832:
830:
826:
821:
818:
815:
813:
809:
806:
803:
801:
797:
794:
791:
789:
785:
782:
779:
777:
773:
770:
767:
765:
761:
757:
753:
748:
743:
732:
729:
725:
722:
719:
715:
710:
706:
703:
702:
698:
695:
693:
689:
684:
681:
678:
676:
672:
669:
666:
664:
660:
657:
654:
652:
648:
645:
642:
640:
636:
633:
630:
628:
624:
620:
616:
612:
608:
603:
598:
587:
584:
580:
577:
574:
570:
565:
561:
558:
557:
553:
550:
548:
544:
539:
536:
533:
531:
527:
524:
521:
519:
515:
512:
509:
507:
503:
500:
497:
495:
491:
488:
485:
483:
479:
475:
471:
467:
463:
458:
454:
450:
439:
436:
432:
429:
426:
422:
417:
413:
410:
409:
405:
402:
400:
396:
391:
388:
385:
383:
379:
376:
373:
371:
367:
364:
361:
359:
355:
352:
349:
347:
343:
340:
337:
335:
331:
327:
323:
318:
314:
310:
299:
296:
292:
289:
286:
282:
277:
273:
270:
269:
265:
262:
260:
256:
251:
248:
245:
243:
239:
236:
233:
231:
227:
224:
221:
219:
215:
212:
209:
207:
203:
200:
197:
195:
191:
187:
183:
179:
175:
170:
166:
162:
151:
148:
144:
141:
138:
134:
129:
125:
122:
121:
117:
114:
112:
108:
103:
100:
97:
95:
91:
88:
85:
83:
79:
76:
73:
71:
67:
64:
61:
59:
55:
52:
49:
47:
43:
40:
37:
33:
28:
24:
20:
5775:Cytoskeleton
5727:
5502:Dystroglycan
5457:Beta catenin
4689:Microtubules
4617:
4557:Beta-keratin
4486:
4435:
4381:
4321:
4243:
4229:
4215:
4152:
3989:
3856:Tropomodulin
3448:cytoskeleton
3293:Gap junction
3215:Motor neuron
3046:
3009:Axon hillock
2985:nerve fibers
2939:Schwann cell
2849:
2832:
2810:
2728:Medium spiny
2641:White matter
2629:Tissue Types
2537:
2533:
2523:
2490:
2486:
2480:
2447:
2443:
2433:
2387:
2383:
2373:
2339:
2335:
2329:
2296:
2292:
2285:
2252:
2248:
2242:
2209:
2205:
2192:
2159:
2155:
2142:
2107:
2103:
2093:
2063:(2): 153–6.
2060:
2056:
2050:
2018:(1): 22–41.
2015:
2012:Cytoskeleton
2011:
2001:
1968:
1964:
1958:
1923:
1919:
1909:
1890:
1884:
1851:
1847:
1841:
1808:
1804:
1798:
1763:
1759:
1749:
1728:
1721:
1697:(2): 81–91.
1694:
1690:
1680:
1645:
1641:
1631:
1596:
1592:
1582:
1547:
1543:
1518:. Retrieved
1514:
1505:
1470:
1466:
1456:
1431:
1391:
1380:
1376:neurogenesis
1353:
1327:
1314:
1306:
1285:white matter
1215:
1196:
1126:
1115:NP_066554.2
1098:NP_005373.2
1081:NP_006149.2
1064:NP_116116.1
1047:NP_006253.2
1027:Amino acids
997:peripherin 2
976:
958:
956:
940:α-internexin
908:cytoskeleton
900:microtubules
883:
879:
878:
836:
699:
618:Alt. symbols
554:
473:Alt. symbols
406:
266:
185:Alt. symbols
118:
5648:Plakophilin
5599:Desmoplakin
5359:Tau protein
4133:Cytokeratin
3929:Tropomyosin
3477:Myofilament
3308:Active zone
3273:Termination
3123:Interneuron
3027:Telodendron
2935:Myelination
2917:Endoneurium
2912:Perineurium
2733:Interneuron
2723:Von Economo
2671:Decussation
2666:Nerve tract
2636:Grey matter
1417:resembling
1334:microtubule
1318:target cell
1301:immunostain
1265:neural tube
1259:are in the
1211:coiled coil
1041:Peripherin
959:neurofibril
858:Swiss-model
750:Identifiers
721:Swiss-model
668:NM_006262.3
605:Identifiers
576:Swiss-model
460:Identifiers
428:Swiss-model
320:Identifiers
288:Swiss-model
172:Identifiers
140:Swiss-model
30:Identifiers
5744:Categories
5728:See also:
5700:Crescentin
5619:Periplakin
5609:Envoplakin
5497:Dystrophin
5114:axonemal:
4608:Internexin
4587:Peripherin
3378:Nociceptor
3118:Multipolar
3067:Nissl body
2944:Neurilemma
2907:Epineurium
2692:Cell Types
1854:: 118–23.
1520:6 December
1448:References
1415:phenotypes
1394:biomarkers
1356:antibodies
1309:vertebrate
1281:Micrograph
1183:cerebellum
1118:111.9 kDA
1101:102.5 kDa
932:peripherin
854:Structures
849:Search for
823:Other data
717:Structures
712:Search for
686:Other data
572:Structures
567:Search for
541:Other data
424:Structures
419:Search for
408:q12.1-13.1
393:Other data
284:Structures
279:Search for
253:Other data
136:Structures
131:Search for
105:Other data
5317:Centrin 3
5312:Centrin 2
5307:Centrin 1
4645:Syncoilin
4550:Not alpha
4116:filaments
4068:Fibrillin
3393:Hair cell
2927:Neuroglia
2889:Funiculus
2778:Microglia
2751:Astrocyte
2708:Pyramidal
2661:Lemniscus
2554:2632-1297
2472:216029229
2336:Neurology
2085:205010517
1121:~200 kDa
1104:~160 kDa
1084:61.5 kDa
1067:55.4 kDa
1050:53.7 kDa
892:cytoplasm
805:NP_006608
764:NCBI gene
627:NCBI gene
523:NM_032727
482:NCBI gene
375:NM_021076
334:NCBI gene
235:NM_005382
194:NCBI gene
87:NM_006158
46:NCBI gene
5683:Nonhuman
5643:Vinculin
5604:Dystonin
5536:Spectrin
5509:Utrophin
5489:Membrane
5444:Catenins
5376:Stathmin
5364:Dynactin
5244:DYNC2LI1
5239:DYNC1LI2
5234:DYNC1LI1
4899:Kinesins
4703:Tubulins
4592:Vimentin
4124:Type 1/2
4026:Profilin
4021:Gelsolin
3883:Troponin
3444:Proteins
3178:Ia or Aα
3108:Unipolar
3057:Dendrite
3042:Axolemma
3037:Axoplasm
2821:Ganglion
2761:Tanycyte
2713:Purkinje
2700:Neuronal
2683:Meninges
2678:Neuropil
2572:37091583
2563:10120172
2515:23675224
2507:14640321
2464:32305278
2424:28241046
2384:PLOS ONE
2364:22681349
2356:19365053
2321:36897027
2277:31052853
2269:19845747
2234:52140127
2226:30171200
2184:18311152
2176:15896809
2134:16000374
2077:11253369
2042:28926211
1993:41152820
1985:10707083
1868:20132798
1825:19737816
1672:22723690
1623:17005864
1497:22956720
1436:See also
1425:and the
1291:showing
1234:Antibody
1188:Purkinje
1133:SDS-PAGE
1087:~70 kDa
1070:~66 kDa
1053:~56 kDa
1024:Protein
1005:vimentin
965:of some
924:vimentin
920:keratins
868:InterPro
731:InterPro
586:InterPro
438:InterPro
298:InterPro
150:InterPro
5670:PLEKHA7
5624:Plectin
5589:Plakins
5514:Ankyrin
5413:Dynamin
5343:Spastin
5338:Katanin
5302:CAMSAP3
5297:CAMSAP2
5292:CAMSAP1
5264:DYNLRB2
5259:DYNLRB1
5229:DYNC1I2
5224:DYNC1I1
5219:DYNC2H1
5214:DYNC1H1
5107:Dyneins
4831:TUBGCP6
4826:TUBGCP5
4821:TUBGCP4
4816:TUBGCP3
4811:TUBGCP2
4640:Synemin
4383:type II
4245:type II
4128:Keratin
4073:Filamin
4014:Destrin
3997:Cofilin
3958:Actinin
3529:Myosins
3446:of the
3320:Autapse
3281:Synapse
3128:Renshaw
3103:Bipolar
2980:Neurons
2833:Ventral
2804:General
2718:Granule
2415:5328385
2392:Bibcode
2313:8863508
2125:1196334
2033:6005378
1950:3084715
1941:6568432
1876:9615612
1833:5883157
1790:2844152
1781:1149198
1713:1633625
1663:3405552
1614:6674481
1565:2109569
1488:3516374
1370:and in
1263:in the
1151:alleles
1011:of the
952:introns
896:neurons
864:Domains
812:UniProt
727:Domains
697:Chr. 12
675:UniProt
582:Domains
552:Chr. 10
530:UniProt
434:Domains
404:Chr. 22
382:UniProt
294:Domains
242:UniProt
146:Domains
94:UniProt
5571:SPTBN5
5566:SPTBN4
5561:SPTBN2
5556:SPTBN1
5546:SPTAN1
5381:Tektin
5274:DYNLT3
5269:DYNLT1
5254:DYNLL2
5249:DYNLL1
5196:DNALI1
5181:DNAH17
5176:DNAH14
5171:DNAH13
5166:DNAH12
5161:DNAH11
5156:DNAH10
5077:KIF26B
5072:KIF26A
5047:KIF21B
5042:KIF21A
5037:KIF20B
5032:KIF20A
5022:KIF18B
5017:KIF18A
5007:KIF16B
4992:KIF13B
4987:KIF13A
4786:TUBB4Q
4771:TUBB2C
4766:TUBB2B
4761:TUBB2A
4741:TUBA4A
4736:TUBA3E
4731:TUBA3D
4726:TUBA3C
4721:TUBA1C
4716:TUBA1B
4711:TUBA1A
4654:Type 5
4613:Nestin
4601:Type 4
4577:Desmin
4570:Type 3
4323:type I
4154:type I
4100:TRIOBP
3766:MYO18B
3761:MYO18A
3757:XVIII
3751:MYO15A
3486:Actins
3173:fibers
2811:Dorsal
2570:
2560:
2552:
2513:
2505:
2470:
2462:
2422:
2412:
2362:
2354:
2319:
2311:
2275:
2267:
2232:
2224:
2182:
2174:
2132:
2122:
2083:
2075:
2040:
2030:
1991:
1983:
1948:
1938:
1897:
1874:
1866:
1831:
1823:
1788:
1778:
1737:
1711:
1670:
1660:
1621:
1611:
1572:
1562:
1495:
1485:
1411:Mutant
1245:embryo
1146:serine
1142:lysine
1013:retina
1001:retina
948:nestin
928:desmin
834:Chr. 1
817:P48681
800:RefSeq
793:600915
755:Symbol
701:q13.12
680:P41219
663:RefSeq
656:170710
610:Symbol
535:Q5SYD2
518:RefSeq
511:605338
465:Symbol
387:P12036
370:RefSeq
363:162230
325:Symbol
264:Chr. 8
247:P07197
230:RefSeq
223:162250
177:Symbol
116:Chr. 8
99:P07196
82:RefSeq
75:162280
35:Symbol
5631:Talin
5614:MACF1
5582:Other
5541:SPTA1
5406:TEKT5
5401:TEKT4
5396:TEKT3
5391:TEKT2
5386:TEKT1
5369:DCTN1
5352:Other
5206:DNAL4
5201:DNAL1
5191:DNAI2
5186:DNAI1
5151:DNAH9
5146:DNAH8
5141:DNAH7
5136:DNAH6
5131:DNAH5
5126:DNAH3
5121:DNAH2
5116:DNAH1
5097:KIFC3
5092:KIFC2
5087:KIFC1
5082:KIF27
5067:KIF25
5062:KIF24
5057:KIF23
5052:KIF22
5027:KIF19
5012:KIF17
5002:KIF15
4997:KIF14
4982:KIF12
4977:KIF11
4957:KIF5C
4952:KIF5B
4947:KIF5A
4942:KIF4B
4937:KIF4A
4932:KIF3C
4927:KIF3B
4922:KIF2C
4917:KIF2A
4912:KIF1B
4907:KIF1A
4879:MAP1B
4874:MAP1A
4841:TUBE1
4836:TUBD1
4806:TUBG2
4801:TUBG1
4796:TUBB8
4791:TUBB6
4781:TUBB4
4776:TUBB3
4756:TUBB1
4746:TUBA8
4095:Espin
4056:Other
4043:Titin
3849:Other
3838:MYLL1
3833:MYLK2
3823:MYLIP
3808:MYL6B
3741:MYO10
3731:MYO9B
3726:MYO9A
3716:MYO7B
3711:MYO7A
3691:MYO5C
3686:MYO5B
3681:MYO5A
3671:MYO3B
3666:MYO3A
3656:MYH16
3651:MYH15
3646:MYH14
3641:MYH13
3636:MYH11
3631:MYH10
3616:MYH7B
3575:MYO1H
3570:MYO1G
3565:MYO1F
3560:MYO1E
3555:MYO1D
3550:MYO1C
3545:MYO1B
3540:MYO1A
3455:Human
3096:Types
2993:Parts
2862:White
2843:Ramus
2826:Ramus
2743:Glial
2540:(2).
2511:S2CID
2468:S2CID
2360:S2CID
2317:S2CID
2273:S2CID
2230:S2CID
2202:(PDF)
2180:S2CID
2152:(PDF)
2081:S2CID
1989:S2CID
1872:S2CID
1829:S2CID
1574:49355
1295:with
1241:Ki 67
1237:stain
1112:1020
912:axons
838:q23.1
829:Locus
769:10763
692:Locus
547:Locus
399:Locus
259:Locus
111:Locus
5715:ParM
5710:MreB
5705:FtsZ
5665:ACF7
5658:PKP2
5653:PKP1
5636:TLN1
5551:SPTB
5529:ANK3
5524:ANK2
5519:ANK1
5428:DNM3
5423:DNM2
5418:DNM1
5322:PCM1
4972:KIF9
4967:KIF7
4962:KIF6
4889:MAP4
4884:MAP2
4851:MAPs
4751:TUBB
4694:MAPs
4692:and
4633:NEFH
4628:NEFM
4623:NEFL
4582:GFAP
4230:none
4088:FLNC
4083:FLNB
4078:FLNA
3828:MYLK
3818:MYL9
3813:MYL7
3803:MYL6
3798:MYL5
3793:MYL4
3788:MYL3
3783:MYL2
3778:MYL1
3707:VII
3701:MYO6
3662:III
3626:MYH9
3621:MYH8
3611:MYH7
3606:MYH6
3601:MYH4
3596:MYH3
3591:MYH2
3586:MYH1
3468:ABPs
3466:and
3019:Axon
3001:Soma
2857:Gray
2838:Root
2816:Root
2568:PMID
2550:ISSN
2503:PMID
2460:PMID
2420:PMID
2352:PMID
2309:PMID
2265:PMID
2222:PMID
2172:PMID
2130:PMID
2073:PMID
2038:PMID
1981:PMID
1946:PMID
1895:ISBN
1864:PMID
1852:1322
1821:PMID
1786:PMID
1735:ISBN
1709:PMID
1668:PMID
1619:PMID
1570:PMID
1522:2019
1493:PMID
1387:glia
1221:and
1205:and
1140:and
1095:916
1078:543
1061:499
1044:470
988:NF-H
984:NF-M
980:NF-L
934:and
788:OMIM
781:7756
776:HGNC
651:OMIM
644:9461
639:HGNC
632:5630
621:NEF4
613:PRPH
506:OMIM
499:6057
494:HGNC
487:9118
476:NEF5
358:OMIM
351:7737
346:HGNC
339:4744
328:NEFH
313:NF-H
218:OMIM
211:7734
206:HGNC
199:4741
188:NEF3
180:NEFM
165:NF-M
70:OMIM
63:7739
58:HGNC
51:4747
39:NEFL
23:NF-L
5479:GAN
5462:APC
4869:EB3
4864:EB2
4859:EB1
4665:A/C
4348:33B
4343:33A
3747:XV
3722:IX
3697:VI
3582:II
3233:SVE
3228:GVE
3223:GSE
3168:SVA
3163:SSA
3158:GVA
3153:GSA
2796:PNS
2621:CNS
2558:PMC
2542:doi
2495:doi
2452:doi
2410:PMC
2400:doi
2344:doi
2301:doi
2257:doi
2214:doi
2164:doi
2160:233
2120:PMC
2112:doi
2065:doi
2028:PMC
2020:doi
1973:doi
1936:PMC
1928:doi
1856:doi
1813:doi
1809:122
1776:PMC
1768:doi
1764:252
1699:doi
1658:PMC
1650:doi
1609:PMC
1601:doi
1560:PMC
1552:doi
1483:PMC
1475:doi
1471:125
1283:of
894:of
758:NES
556:q24
468:INA
268:p21
120:p21
5746::
4675:B2
4670:B1
4663::
4539:80
4534:79
4529:78
4524:77
4519:76
4514:75
4509:74
4504:73
4499:72
4494:71
4478:40
4473:39
4468:28
4463:27
4458:26
4453:25
4448:24
4443:23
4418:86
4413:85
4408:84
4403:83
4398:82
4393:81
4373:38
4368:37
4363:36
4358:35
4353:34
4338:32
4333:31
4290:6C
4285:6B
4280:6A
4260:2A
4235:21
4223:18
4209:20
4204:19
4199:17
4194:16
4189:15
4184:14
4179:13
4174:12
4169:10
3773:LC
3737:X
3677:V
3536:I
3519:G2
3514:G1
3509:C1
3499:A2
3494:A1
2937::
2566:.
2556:.
2548:.
2536:.
2532:.
2509:.
2501:.
2491:14
2489:.
2466:.
2458:.
2448:29
2446:.
2442:.
2418:.
2408:.
2398:.
2388:12
2386:.
2382:.
2358:.
2350:.
2340:72
2338:.
2315:.
2307:.
2297:67
2295:.
2271:.
2263:.
2253:17
2251:.
2228:.
2220:.
2210:14
2208:.
2204:.
2178:.
2170:.
2158:.
2154:.
2128:.
2118:.
2108:16
2106:.
2102:.
2079:.
2071:.
2059:.
2036:.
2026:.
2016:75
2014:.
2010:.
1987:.
1979:.
1967:.
1944:.
1934:.
1922:.
1918:.
1870:.
1862:.
1850:.
1827:.
1819:.
1807:.
1784:.
1774:.
1762:.
1758:.
1707:.
1695:22
1693:.
1689:.
1666:.
1656:.
1646:32
1644:.
1640:.
1617:.
1607:.
1597:26
1595:.
1591:.
1568:.
1558:.
1548:66
1546:.
1542:.
1530:^
1513:.
1491:.
1481:.
1469:.
1465:.
1401:,
1015:.
969:.
930:,
926:,
884:NF
4385:/
4325:/
4300:8
4295:7
4275:5
4270:4
4265:3
4255:1
4247:/
4164:9
4156:/
4135:)
4130:,
4126:(
4036:2
4031:1
4007:2
4002:1
3978:4
3973:3
3968:2
3963:1
3949:4
3944:3
3939:2
3934:1
3922:3
3919:2
3916:1
3913:I
3908:2
3905:1
3902:C
3897:3
3894:2
3891:1
3888:T
3876:4
3871:3
3866:2
3861:1
3577:)
3504:B
3436:e
3429:t
3422:v
3291:/
3212:/
3142:/
3079:/
2982:/
2880:)
2871:(
2605:e
2598:t
2591:v
2574:.
2544::
2538:5
2517:.
2497::
2474:.
2454::
2428:,
2426:.
2402::
2394::
2368:,
2366:.
2346::
2323:.
2303::
2279:.
2259::
2236:.
2216::
2186:.
2166::
2136:.
2114::
2087:.
2067::
2061:1
2044:.
2022::
1995:.
1975::
1969:2
1952:.
1930::
1924:6
1903:.
1878:.
1858::
1835:.
1815::
1792:.
1770::
1743:.
1715:.
1701::
1674:.
1652::
1625:.
1603::
1576:.
1554::
1524:.
1499:.
1477::
1303:.
882:(
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.