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Mycosis fungoides

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116: 40: 124: 193:(SS) are related conditions, with the same type of cancer T-lymphocytes, that initially grow in different body compartments. SS cells are found mainly in the blood, whereas MF typically involves the skin. In advanced stages of MF, the cancer cells move from the skin into other organs and the bloodstream; this progression is referred to as "leukemic mycosis fungoides", "SĂ©zary syndrome preceded by mycosis fungoides", or "secondary mycosis fungoides". 163:
plaque stage follows the patch stage of mycosis fungoides. It is characterized by the presence of raised lesions that appear reddish-brown; in darker skin tones, plaques may have a greyish or silver appearance. Both patch and plaque stages are considered early-stage mycosis fungoides. The tumour stage typically shows large irregular lumps. Tumours can develop from plaques or normal skin in any region of the body, including the face and head regions.
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findings, making it difficult to distinguish from other inflammatory dermatoses. Childhood Mycosis fungoides makes up 0.5% to 7.0% of cases. Although data on childhood MF is limited, a 2021 systematic review observed that there is a significant delay in the diagnosis of childhood MF which may negatively affect a child's prognosis. Notably, most pediatric persons with MF present with early-stage disease.
269: 186:(pruritus) is the most commonly reported symptom of people experiencing mycosis fungoides with up to 88% of people reporting varying intensities of pruritus that typically worsens as the disease progresses. Those that experience intense pruritus commonly indicate that it negatively affects their quality of life emotionally, functionally and physically. 359:). PUVA is a photochemotherapy that involves topical or oral administration of the photosensitizing drug psoralen followed by skin exposure to ultraviolet radiation. Systemic treatments of mycosis fungoides often lead to resistance; as such, additional treatment options are often necessary in advanced disease. 346:
Most patients with mycosis fungoides have early-stage disease (Stage IA-IIA) at the time of their initial diagnosis. People with early stage disease that is primarily confined to the skin have a favorable prognosis. People with advanced stage (Stage IIB-IVB) are often refractory to treatment and have
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The symptoms of mycosis fungoides are categorized into three clinical stages: the patch stage, the plaque stage, and the tumour stage. The patch stage is defined by flat, reddish patches of varying sizes that may have a wrinkled appearance. They can also look yellowish in people with darker skin. The
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A 1999 US-based study of people with CLL's medical records observed a 5-year relative survival rate of 77%, and a 10-year relative survival rate of 69%. After 11 years, the observed relative survival rate remained around 66%. Poorer survival is correlated with advanced age and black race. Superior
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Traditionally, mycosis fungoides has been divided into three stages: premycotic, mycotic and tumorous. The premycotic stage clinically presents as an erythematous (red), itchy, scaly lesion. Microscopic appearance is non-diagnostic and represented by chronic nonspecific dermatosis associated with
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The symptoms displayed are progressive, with early stages consisting of lesions presented as scaly patches. Lesions often initially develop on the trunk of the body in places that are rarely exposed to the sun, such as the buttocks. These lesions can start as insignificant patches and may remain
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erythematosus), as well as other cutaneous lymphomas. Several biopsies are recommended, as the key microscopic features are often absent in early MF, and a complete diagnosis requires a combination of clinical and histological study. Furthermore, long periods of treatment can alter the biopsy
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In the mycotic stage, infiltrative plaques appear and biopsy shows a polymorphous inflammatory infiltrate in the dermis that contains small numbers of frankly atypical lymphoid cells. These cells may line up individually along the epidermal basal layer. The latter finding if unaccompanied by
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Accurate staging of mycosis fungoides is essential to determine appropriate treatment and prognosis. Staging is based on the tumor, node, metastasis, blood (TNMB) classification proposed by the Mycosis Fungoides Cooperative Group and revised by the International Society for Cutaneous
2010:"Revisions to the staging and classification of mycosis fungoides and Sezary syndrome: a proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC)" 408:). Treatments are often used in combination. Due to the possible adverse effects of treatment options in early disease it is recommended to begin therapy with topical and skin-directed treatments before progressing to more systemic therapies. In 2010, the 343:
Lymphomas/European Organization of Research and Treatment of Cancer. This staging system examines the extent of skin involvement (T), presence of lymph node (N), visceral disease (M), and presence of Sezary cells in the peripheral blood (B).
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Jawed SI, Myskowski PL, Horwitz S, Moskowitz A, Querfeld C (February 2014). "Primary cutaneous T-cell lymphoma (mycosis fungoides and SĂ©zary syndrome): part II. Prognosis, management, and future directions".
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across various racial groups reported in different studies. The incidence of mycosis fungoides was seen to be increasing between 2000 and 2020, although certain regions have demonstrated some stabilization.
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It is rare for mycosis fungoides to appear before age 20; the average age of onset is between 45 and 55 years of age for people with patch and plaque disease only, but is over 60 for people who present with
227:, a part of the immune system. These T cells are skin-associated, meaning they are biochemically and biologically most related to the skin, in a dynamic manner. Mycosis fungoides is the most common type of 2192: 239:
Diagnosis often requires a combination of clinical and pathological studies. Diagnosis is sometimes difficult because the early phases of the disease often resemble inflammatory dermatoses (such as
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Other treatments have been suggested, however, larger and more extensive research is needed to identify effective treatment strategies for this disease. Suggested treatments include light therapy,
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While the cause remains unclear, most cases are not hereditary. Most cases are in people over 20 years of age, and it is more common in men than women. Treatment options include sunlight exposure,
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the disease, various tests may be ordered, to assess nodes, blood and internal organs, but most patients present with disease apparently confined to the skin, as patches (flat spots) and
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Large cell transformation, where clonally identical lymphocytes in the lesion exhibit hypertrophy. In transformed cells, presence of the CD30 receptor is associated with improved survival
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an unfavorable prognosis. Treatment options for people with advanced stage disease are designed to reduce tumor burden, delay disease progression, and preserve quality of life.
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Travaglino A, Russo D, Varricchio S, Pignatiello S, Baldo A, Picardi M, et al. (August 2021). "Prognostic Significance of CD30 in Transformed Mycosis Fungoides".
3462: 297:, aggregates of four or more atypical lymphocytes arranged in the epidermis. Pautrier microabcesses are characteristic of mycosis fungoides but are generally absent. 438:
which has been shown to improve progression-free survival. It was approved by the US FDA in 2018 for use in people with relapsed or refractory mycosis fungoides or
449:(ECP: a type of phototherapy) for treating people with mycosis fungoides. There is also no evidence to support the combination treatment of PUVA and intralesional 3579: 2096: 1433:"Spotlight on Mogamulizumab-Kpkc for Use in Adults with Relapsed or Refractory Mycosis Fungoides or SĂ©zary Syndrome: Efficacy, Safety, and Patient Selection" 4169: 1887: 3978: 490:
survival was observed for married women compared with other gender and marital-status groups. The complete remission rate in children is nearly 30%.
1486: 4192: 1813: 1509:"New insights into the pathophysiology and treatment of chronic itch in patients with end-stage renal disease, chronic liver disease, and lymphoma" 3544: 4233: 3934: 593: 3273: 2685: 171:(when the skin is lighter than normal) of lesions are less common but can be found in children, adolescents and/or dark-skinned individuals. 3624: 231:(CTCL), but there are many other types of CTCL that have nothing to do with mycosis fungoides and these disorders are treated differently. 1889:
Descriptions des maladies de la peau observées a l'HÎpital Saint-Louis, et exposition des meilleures méthodes suivies pour leur traitement
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is very misleading—it loosely means "mushroom-like fungal disease". The disease, however, is not a fungal infection but rather a type of
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Jung JM, Lim DJ, Won CH, Chang SE, Lee MW, Lee WJ (April 2021). "Mycosis Fungoides in Children and Adolescents: A Systematic Review".
88:. It generally affects the skin, but may progress internally over time. Symptoms include rash, tumors, skin lesions, and itchy skin. 3702: 3500: 1209:
Greer JP, Arber DA, List AF, Foerster J (2014). Greer JP, Arber DA, Glader B, List AF, Means Jr R, Rodgers GM, Foerster J (eds.).
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spongiosis is highly suggestive of mycosis fungoides. In the tumorous stage a dense infiltrate of medium-sized lymphocytes with
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Cerroni L (March 2018). "Mycosis fungoides-clinical and histopathologic features, differential diagnosis, and treatment".
4077: 3697: 3495: 3379: 2107: 4025: 3736: 1611:"The changing survival of patients with mycosis fungoides: a population-based assessment of trends in the United States" 205:). These abnormal cells have a preference for localizing and proliferating uncontrolled in the outer layer of the skin ( 3968: 2774: 1218: 3266: 2675: 1314: 465:
Treatment for adults and children with mycosis fungoides often differs because of the safety profiles of modalities.
409: 1893: 564:. It was so named because Alibert described the skin tumors of a severe case as having a mushroom-like appearance. 3929: 2784: 983: 4159: 4151: 4010: 3888: 3827: 3813: 3707: 3648: 3485: 3411: 2743: 2369: 896:"Quality of life in patients with Mycosis Fungoides and SĂ©zary Syndrome: a systematic review of the literature" 213:. It is hypothesized that the genetic mutations in these cancer cells lead to increased growth and escape from 4207: 4117: 4067: 3963: 3692: 3476: 2936: 2627: 2464: 474: 386: 4099: 4005: 3988: 3796: 3350: 3259: 3103: 2858: 2549: 2479: 984:"Mycosis Fungoides (Including SĂ©zary Syndrome) Treatment (PDQ)–Patient Version - National Cancer Institute" 603: 537:, he joked about the coincidence: "Can you imagine that? Cancer with my name on it — personalized cancer!" 446: 4040: 3913: 3619: 2853: 2384: 2339: 1154:
Jung, Joon Min; Lim, Dong Jun; Won, Chong Hyun; Chang, Sung Eun; Lee, Mi Woo; Lee, Woo Jin (2021-04-01).
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The most commonly recommended first-line treatment for mycosis fungoides is psoralen plus ultraviolet A (
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Ottevanger R, de Bruin DT, Willemze R, Jansen PM, Bekkenk MW, de Haas ER, et al. (August 2021).
573: 561: 228: 85: 2170: 4045: 3873: 2971: 2617: 2554: 2449: 2118: 512: 1094:"Cutaneous T-cell lymphoma: 2017 update on diagnosis, risk-stratification, and management: WILCOX" 845: 3511: 3236: 2931: 2650: 2622: 2252: 2008:
Olsen E, Vonderheid E, Pimpinelli N, Willemze R, Kim Y, Knobler R, et al. (September 2007).
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Duvic M, Foss FM (December 2007). "Mycosis fungoides: pathophysiology and emerging therapies".
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Hwang ST, Janik JE, Jaffe ES, Wilson WH (March 2008). "Mycosis fungoides and SĂ©zary syndrome".
1213:(Thirteenth ed.). Wolters Kluwer, Lippincott Williams & Wilkins Health. p. 1957. 466: 424: 588: 4071: 3661: 3634: 3555: 3457: 3113: 3040: 2728: 2262: 2242: 1701:"Incidence of mycosis fungoides and SĂ©zary syndrome in the Netherlands between 2000 and 2020" 598: 214: 3251: 268: 3868: 3480: 3391: 3299: 2459: 2257: 2232: 647:"'Could it be mycosis fungoides?': an approach to diagnosing patch stage mycosis fungoides" 578: 534: 312: 8: 3668: 3452: 3422: 3181: 3118: 3093: 3067: 2921: 2899: 2494: 2454: 2374: 2364: 2085: 1650:
Kaufman AE, Patel K, Goyal K, O'Leary D, Rubin N, Pearson D, et al. (October 2020).
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Ottevanger R, van Beugen S, Evers AW, Willemze R, Vermeer MH, Quint KD (December 2021).
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In the tumour stage, the cancer cells move into the dermis (the deeper layer of skin)
140: 92: 52: 3882: 1137: 1037: 439: 393: 3982: 3761: 3629: 3528: 3186: 3035: 2941: 2889: 2759: 2534: 2469: 2158: 2021: 1988: 1951: 1766: 1761: 1749: 1720: 1712: 1671: 1663: 1622: 1574: 1570: 1528: 1520: 1454: 1444: 1400: 1392: 1353: 1279: 1171: 1167: 1115: 1105: 1064: 1017: 915: 907: 816: 812: 808: 756: 712: 702: 658: 583: 168: 3755: 3750: 3559: 3443: 3309: 3304: 3171: 3098: 2769: 2484: 2329: 2267: 2123: 2026: 2009: 511:). Mycosis fungoides is more common in males than in females with differences in 421: 870: 844:
Shinkai K, Fox LP (2022), Papadakis MA, McPhee SJ, Rabow MW, McQuaid KR (eds.),
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was diagnosed with a cutaneous T-cell lymphoma, or mycosis fungoides. Once in
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Hodak E, Amitay-Laish I (2019-05-01). "Mycosis fungoides: A great imitator".
760: 672: 623: 428: 397: 367: 319: 291:(the most superficial layer of skin). This is referred to as epidermotropism. 248: 202: 132: 47:
Skin lesions on the knee of a 52-year-old male patient with mycosis fungoides
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10.1002/(SICI)1097-0142(19990101)85:1<208::AID-CNCR28>3.0.CO;2-2
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died of mycosis fungoides after living with the condition for four decades.
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Valipour A, JĂ€ger M, Wu P, Schmitt J, Bunch C, Weberschock T (July 2020).
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The advanced stage of mycosis fungoides is characterized by generalized
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Histopathology of Pautrier microabscesses in cutaneous T cell lymphoma.
210: 61: 1716: 1667: 1652:"Mycosis fungoides: developments in incidence, treatment and survival" 1110: 1093: 1069: 1052: 911: 707: 690: 552:
Mycosis fungoides was first described in 1806 by French dermatologist
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Presence of cancer cells with twisted contours (cerebriform nuclei)
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In the patch and plaque stages, the cancer cells are seen in the
224: 209:). The abnormal cells may later involve other organs such as the 183: 2112: 1698: 3745: 2637: 2582: 2349: 2344: 2318: 2227: 2070: 1892:(in French). Paris: Barrois l'ainĂ©. p. 286. Archived from 1051:
Rubio-Gonzalez B, Zain J, Rosen ST, Querfeld C (January 2017).
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used as a treatment for pruritus in cutaneous T-cell lymphoma.
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Journal of the European Academy of Dermatology and Venereology
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Journal of the European Academy of Dermatology and Venereology
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Non-mycosis fungoides CD30− cutaneous large T-cell lymphoma
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Mycosis fungoides is caused by abnormal white blood cells (
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The criteria for the disease are established on the skin
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There is no evidence to support the use of acitretin or
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Tumour stage mycosis fungoides seen on the head and neck
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Additionally, the disease is an unusual expression of
1941: 1860: 2048: 1906: 1430: 688: 1748:Korgavkar K, Xiong M, Weinstock M (November 2013). 1597: 950: 689:Hristov AC, Tejasvi T, Wilcox RA (September 2019). 469:is commonly considered for children, as opposed to 3979:Peripheral T-cell lymphoma not otherwise specified 1835: 644: 3801:Precursor T acute lymphoblastic leukemia/lymphoma 3355:Precursor B acute lymphoblastic leukemia/lymphoma 2201:Diseases of the skin and appendages by morphology 1381:"A clinical review of phototherapy for psoriasis" 1298: 1007: 178:(red rash covering most of the body) with severe 127:Plaque of mycosis fungoides on foot treated with 4225: 3545:Nodular lymphocyte predominant Hodgkin lymphoma 1608: 1560: 1506: 1245:. 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St. Louis: Mosby. p. 1867. 1705:The British Journal of Dermatology 1549: 1421: 1323: 1227: 1022:10.1016/j.clindermatol.2019.01.004 280:by the presence of the following: 145:Lehigh Valley Hospital–Cedar Crest 14: 4255: 2676:Transient acantholytic dermatosis 2044: 1790:"Mr. T, T cell lymphoma survivor" 1305:O'Connell TX (28 November 2013). 775: 733: 679: 633: 540:Popular British television actor 481:, which is often used in adults. 410:U.S. Food and Drug Administration 318:Peripheral smear will often show 247:, lichenoid dermatoses including 2785:Idiopathic guttate hypomelanosis 1993:10.1053/j.seminoncol.2007.11.006 1850:from the original on 2022-06-18. 1802:from the original on 2021-12-13. 1525:10.1111/j.1365-4632.2009.04249.x 1092:Wilcox, Ryan A. (October 2017). 524: 167:undiagnosed for up to a decade. 3930:CD30+ cutaneous T-cell lymphoma 2795:Hypopigmented mycosis fungoides 1879: 1828: 1806: 1782: 1741: 1692: 1643: 1500: 1379:Zhang P, Wu MX (January 2018). 1372: 1263: 1202: 1085: 1044: 1001: 976: 507:(red skin) or a leukemic form ( 493: 4160:Cutaneous lymphoid hyperplasia 4152:Cutaneous lymphoid hyperplasia 4011:Adult T-cell leukemia/lymphoma 3889:Adult T-cell leukemia/lymphoma 3828:Anaplastic large-cell lymphoma 3708:Primary cutaneous immunocytoma 3649:Splenic marginal zone lymphoma 3036:Lichen sclerosis et atrophicus 2744:Subcorneal pustular dermatosis 2370:Infantile digital fibromatosis 1767:10.1001/jamadermatol.2013.5526 1575:10.1001/jamadermatol.2021.0083 1211:Wintrobe's clinical hematology 1172:10.1001/jamadermatol.2021.0083 1098:American Journal of Hematology 1057:British Journal of Haematology 944: 887: 862: 837: 813:10.1002/14651858.CD008946.pub3 695:American Journal of Hematology 616: 1: 4208:Lymphoproliferative disorders 4118:Lymphoproliferative disorders 4068:Extranodal NK-T-cell lymphoma 3940:Lymphomatoid papulosis type A 3919:Lymphomatoid papulosis type B 3833:Lymphomatoid papulosis type A 3693:Diffuse large B-cell lymphoma 2628:Epidermolysis bullosa simplex 2465:Langerhans cell histiocytosis 1956:10.1016/S0140-6736(08)60420-1 609: 475:mechlorethamine hydrochloride 394:total skin electron radiation 387:histone deacetylase inhibitor 84:, is the most common form of 4100:Acute biphenotypic leukaemia 3989:Subcutaneous T-cell lymphoma 3104:Systemic lupus erythematosus 2859:Systemic lupus erythematosus 2550:Systemic lupus erythematosus 2027:10.1182/blood-2007-03-055749 1820:. March 2000. Archived from 953:"Peripheral T-Cell Lymphoma" 869:Ipenburg NA, Aird W (eds.). 604:List of cutaneous conditions 484: 447:extracorporeal photopheresis 350: 263: 234: 7: 4041:Aggressive NK-cell leukemia 3914:Pleomorphic T-cell lymphoma 3620:Lymphomatoid granulomatosis 2385:Lymphangioma circumscriptum 567: 460: 400:, systemic therapies (e.g. 189:Mycosis fungoides (MF) and 119:Plaque of mycosis fungoides 10: 4260: 3207:Mucous membrane pemphigoid 1925:Neoplastic Hematopathology 1358:10.1016/j.jaad.2013.08.033 1237:Vaidya T, Badri T (2021). 651:Journal of Hematopathology 547: 325: 4185: 4150: 4108: 4090: 4054: 4024: 3997: 3952: 3897: 3851: 3842: 3782: 3744: 3735: 3683: 3593: 3554: 3510: 3432: 3401: 3363: 3342: 3331: 3298: 3294: 3170: 3137: 3081: 3066: 3057: 3014: 2985: 2964: 2955: 2908: 2867: 2836: 2825: 2807: 2752: 2694: 2636: 2573: 2493: 2422: 2411: 2402: 2317: 2281: 2213: 2206: 2144: 2052: 1863:Dermatology: 2-Volume Set 1397:10.1007/s10103-017-2360-1 1385:Lasers in Medical Science 664:10.1007/s12308-015-0247-2 574:Cutaneous T-cell lymphoma 229:cutaneous T-cell lymphoma 86:cutaneous T-cell lymphoma 51: 46: 37: 29: 24: 4193:Hematological malignancy 4046:Blastic NK cell lymphoma 3874:Granulomatous slack skin 3630:Classic Hodgkin lymphoma 3529:Classic Hodgkin lymphoma 2972:Thrombocytopenic purpura 2618:Dermatitis herpetiformis 2603:Acute contact dermatitis 2555:Pityriasis rubra pilaris 2480:Wiskott–Aldrich syndrome 2450:Lichen simplex chronicus 2330:Epidermal inclusion cyst 761:10.12788/j.sder.2018.002 295:Pautrier's microabcesses 255:, and chronic cutaneous 196: 3237:Squamous-cell carcinoma 3232:Systemic histoplasmosis 2623:Porphyria cutanea tarda 2253:Squamous-cell carcinoma 554:Jean-Louis-Marc Alibert 414:orphan drug designation 377:, topical and systemic 182:(itching) and scaling. 3212:Cicatricial pemphigoid 3129:Acne keloidalis nuchae 3124:Folliculitis decalvans 1987:(6 Suppl 5): S21–S28. 1010:Clinics in Dermatology 562:non-Hodgkin's lymphoma 425:competitive antagonist 273: 159: 151: 120: 78:Alibert-Bazin syndrome 33:Alibert-Bazin syndrome 4072:Angiocentric lymphoma 3662:AIDS-related lymphoma 3486:Splenic marginal zone 3114:Loose anagen syndrome 3041:Necrobiosis lipoidica 2977:Actinic/solar purpura 2651:Insect bite reactions 2440:Seborrheic dermatitis 2263:Merkel-cell carcinoma 2243:Molluscum contagiosum 1352:(2): 223.e1–223.e17. 599:Angiocentric lymphoma 271: 215:programmed cell death 157: 126: 118: 4170:with nodular pattern 3869:Pagetoid reticulosis 3481:marginal zone B-cell 2937:Annulare centrifugum 2460:Glucagonoma syndrome 2258:Basal-cell carcinoma 2233:Seborrheic keratosis 1981:Seminars in Oncology 1450:10.2147/DDDT.S185896 1307:USMLE Step 2 Secrets 1284:10.1093/ajcp/aqaa261 579:Pagetoid reticulosis 381:, local superficial 368:mainly NB-UVB 312 nm 339:expands the dermis. 3669:Helicobacter pylori 3496:Nodal marginal zone 3423:Hairy cell leukemia 3289:and related disease 3182:Aphthous stomatitis 3119:Lichen planopilaris 3094:Androgenic alopecia 2900:Fixed drug eruption 2475:Pemphigus foliaceus 2375:Granular cell tumor 1923:Knowles DM (2000). 1907:Cerroni, 2007, p.13 1886:Alibert JL (1806). 1846:. 23 October 2011. 1239:"Mycosis Fungoides" 520:Culture and society 436:monoclonal antibody 82:granuloma fungoides 4213:Lymphoid leukemias 4133:Leukemoid reaction 3969:Angioimmunoblastic 3635:Burkitt's lymphoma 3202:Pemphigus vulgaris 3031:Granuloma annulare 2895:Carcinoid syndrome 2780:Tuberous sclerosis 2739:Coccidioidomycosis 2613:Bullous pemphigoid 2608:Pemphigus vulgaris 2540:Secondary syphilis 2430:Contact dermatitis 2145:External resources 420:lotion, a topical 337:cerebriform nuclei 274: 160: 152: 121: 111:Signs and symptoms 4221: 4220: 4146: 4145: 4086: 4085: 4020: 4019: 3948: 3947: 3864:Mycosis fungoides 3731: 3730: 3589: 3588: 3533:Nodular sclerosis 3448:follicular B cell 3249: 3248: 3245: 3244: 3089:Telogen effluvium 3053: 3052: 3049: 3048: 3010: 3009: 3006: 3005: 2951: 2950: 2803: 2802: 2671:Lichen spinulosus 2666:Keratosis pilaris 2545:Mycosis fungoides 2445:Stasis dermatitis 2435:Atopic dermatitis 2398: 2397: 2273:Trichoepithelioma 2248:Actinic keratosis 2168: 2167: 1950:(9616): 945–957. 1934:978-0-683-30246-2 1872:978-1-4160-2999-1 1843:Independent.co.uk 1760:(11): 1295–1299. 1717:10.1111/bjd.20048 1668:10.1111/jdv.16325 1662:(10): 2288–2294. 1111:10.1002/ajh.24876 1104:(10): 1085–1102. 1070:10.1111/bjh.14402 912:10.1111/jdv.17570 906:(12): 2377–2387. 708:10.1002/ajh.25577 558:mycosis fungoides 93:ultraviolet light 74:Mycosis fungoides 71: 70: 25:Mycosis fungoides 19:Medical condition 4251: 3983:Lennert lymphoma 3849: 3848: 3780: 3779: 3742: 3741: 3607:Primary effusion 3340: 3339: 3329: 3328: 3296: 3295: 3276: 3269: 3262: 3253: 3252: 3187:Oral candidiasis 3064: 3063: 2962: 2961: 2890:Erythema nodosum 2834: 2833: 2823: 2822: 2816: 2815: 2760:Tinea versicolor 2598:Bullous impetigo 2535:Pityriasis rosea 2470:Lichen sclerosus 2455:Darier's disease 2420: 2419: 2409: 2408: 2365:Kaposi's sarcoma 2211: 2210: 2195: 2188: 2181: 2172: 2171: 2050: 2049: 2039: 2029: 2020:(6): 1713–1722. 2004: 1975: 1938: 1909: 1904: 1898: 1897: 1883: 1877: 1876: 1858: 1852: 1851: 1839: 1832: 1826: 1825: 1810: 1804: 1803: 1786: 1780: 1779: 1769: 1754:JAMA Dermatology 1745: 1739: 1738: 1728: 1696: 1690: 1689: 1679: 1647: 1641: 1640: 1630: 1606: 1595: 1594: 1563:JAMA Dermatology 1558: 1547: 1546: 1536: 1504: 1498: 1497: 1495: 1494: 1485:. Archived from 1479: 1473: 1472: 1462: 1452: 1428: 1419: 1418: 1408: 1376: 1370: 1369: 1340: 1321: 1320: 1302: 1296: 1295: 1267: 1261: 1260: 1258: 1257: 1234: 1225: 1224: 1206: 1200: 1199: 1160:JAMA Dermatology 1151: 1142: 1141: 1123: 1113: 1089: 1083: 1082: 1072: 1048: 1042: 1041: 1005: 999: 998: 996: 995: 980: 974: 973: 972: 971: 948: 942: 941: 923: 891: 885: 884: 882: 881: 866: 860: 859: 858: 857: 841: 835: 834: 824: 792: 773: 772: 744: 731: 730: 720: 710: 701:(9): 1027–1041. 686: 677: 676: 666: 642: 631: 620: 589:SĂ©zary's disease 584:Premycotic phase 169:Hypopigmentation 76:, also known as 42: 22: 21: 4259: 4258: 4254: 4253: 4252: 4250: 4249: 4248: 4224: 4223: 4222: 4217: 4181: 4142: 4104: 4092: 4082: 4050: 4029: 4016: 3993: 3954: 3944: 3893: 3838: 3786: 3784: 3759: 3754: 3748: 3727: 3679: 3585: 3562: 3550: 3506: 3444:germinal center 3428: 3397: 3359: 3335: 3333: 3313: 3308: 3302: 3290: 3280: 3250: 3241: 3173: 3166: 3133: 3099:Alopecia areata 3077: 3059: 3045: 3002: 2981: 2957: 2947: 2904: 2863: 2849:Viral exanthems 2827: 2811: 2809: 2799: 2770:Pityriasis alba 2748: 2690: 2632: 2569: 2489: 2485:Zinc deficiency 2415: 2413: 2394: 2322: 2313: 2277: 2268:Nevus sebaceous 2202: 2199: 2169: 2164: 2163: 2140: 2139: 2061: 2047: 2042: 1935: 1918: 1916:Further reading 1913: 1912: 1905: 1901: 1884: 1880: 1873: 1859: 1855: 1834: 1833: 1829: 1812: 1811: 1807: 1788: 1787: 1783: 1746: 1742: 1697: 1693: 1648: 1644: 1607: 1598: 1559: 1550: 1505: 1501: 1492: 1490: 1481: 1480: 1476: 1429: 1422: 1377: 1373: 1341: 1324: 1317: 1303: 1299: 1268: 1264: 1255: 1253: 1235: 1228: 1221: 1207: 1203: 1152: 1145: 1090: 1086: 1049: 1045: 1006: 1002: 993: 991: 982: 981: 977: 969: 967: 949: 945: 892: 888: 879: 877: 867: 863: 855: 853: 842: 838: 807:(7): CD008946. 793: 776: 745: 734: 687: 680: 643: 634: 621: 617: 612: 570: 550: 527: 522: 509:SĂ©zary syndrome 496: 487: 467:Narrowband UV-B 463: 422:opioid receptor 353: 328: 266: 237: 199: 191:SĂ©zary syndrome 113: 97:corticosteroids 20: 17: 12: 11: 5: 4257: 4247: 4246: 4241: 4236: 4219: 4218: 4216: 4215: 4210: 4205: 4203:Leukemia cutis 4200: 4195: 4189: 4187: 4183: 4182: 4180: 4179: 4174: 4173: 4172: 4167: 4156: 4154: 4148: 4147: 4144: 4143: 4141: 4140: 4135: 4130: 4124: 4114: 4112: 4106: 4105: 4103: 4102: 4096: 4094: 4088: 4087: 4084: 4083: 4081: 4080: 4075: 4058: 4056: 4052: 4051: 4049: 4048: 4043: 4037: 4035: 4022: 4021: 4018: 4017: 4015: 4014: 4001: 3999: 3995: 3994: 3992: 3991: 3986: 3976: 3971: 3966: 3960: 3958: 3950: 3949: 3946: 3945: 3943: 3942: 3937: 3932: 3922: 3921: 3916: 3911: 3901: 3899: 3895: 3894: 3892: 3891: 3883:SĂ©zary disease 3877: 3876: 3871: 3866: 3857: 3855: 3846: 3840: 3839: 3837: 3836: 3830: 3818: 3817: 3814:Prolymphocytic 3804: 3790: 3788: 3777: 3776: 3775: 3769: 3739: 3733: 3732: 3729: 3728: 3726: 3725: 3720: 3715: 3710: 3705: 3700: 3695: 3689: 3687: 3681: 3680: 3678: 3677: 3665: 3653: 3652: 3651: 3639: 3638: 3637: 3632: 3627: 3622: 3610: 3597: 3595: 3591: 3590: 3587: 3586: 3584: 3583: 3574: 3572: 3552: 3551: 3549: 3548: 3536: 3525: 3523: 3508: 3507: 3505: 3504: 3498: 3493: 3488: 3472: 3471: 3465: 3460: 3455: 3439: 3437: 3430: 3429: 3427: 3426: 3414: 3412:Prolymphocytic 3408: 3406: 3399: 3398: 3396: 3395: 3383: 3370: 3368: 3361: 3360: 3358: 3348: 3346: 3337: 3326: 3325: 3324: 3292: 3291: 3279: 3278: 3271: 3264: 3256: 3247: 3246: 3243: 3242: 3240: 3239: 3234: 3229: 3224: 3222:Coxsackievirus 3219: 3214: 3209: 3204: 3199: 3194: 3189: 3184: 3178: 3176: 3168: 3167: 3165: 3164: 3159: 3154: 3149: 3143: 3141: 3135: 3134: 3132: 3131: 3126: 3121: 3116: 3111: 3106: 3101: 3096: 3091: 3085: 3083: 3079: 3078: 3076: 3075: 3072: 3070: 3061: 3055: 3054: 3051: 3050: 3047: 3046: 3044: 3043: 3038: 3033: 3028: 3018: 3016: 3012: 3011: 3008: 3007: 3004: 3003: 3001: 3000: 2995: 2989: 2987: 2983: 2982: 2980: 2979: 2974: 2968: 2966: 2959: 2953: 2952: 2949: 2948: 2946: 2945: 2939: 2934: 2932:Gyratum repens 2929: 2924: 2918: 2912: 2910: 2906: 2905: 2903: 2902: 2897: 2892: 2887: 2882: 2877: 2871: 2869: 2865: 2864: 2862: 2861: 2856: 2854:Toxic erythema 2851: 2846: 2844:Drug eruptions 2840: 2838: 2831: 2820: 2813: 2805: 2804: 2801: 2800: 2798: 2797: 2792: 2787: 2782: 2777: 2772: 2767: 2762: 2756: 2754: 2750: 2749: 2747: 2746: 2741: 2736: 2731: 2726: 2721: 2716: 2711: 2706: 2700: 2698: 2692: 2691: 2689: 2688: 2683: 2681:Lichen nitidus 2678: 2673: 2668: 2663: 2658: 2653: 2648: 2642: 2640: 2634: 2633: 2631: 2630: 2625: 2620: 2615: 2610: 2605: 2600: 2595: 2590: 2585: 2583:Herpes simplex 2579: 2577: 2571: 2570: 2568: 2567: 2562: 2557: 2552: 2547: 2542: 2537: 2532: 2526: 2521: 2516: 2511: 2505: 2499: 2497: 2491: 2490: 2488: 2487: 2482: 2477: 2472: 2467: 2462: 2457: 2452: 2447: 2442: 2437: 2432: 2426: 2424: 2417: 2406: 2400: 2399: 2396: 2395: 2393: 2392: 2387: 2382: 2377: 2372: 2367: 2362: 2357: 2352: 2347: 2342: 2337: 2332: 2326: 2324: 2315: 2314: 2312: 2311: 2306: 2301: 2296: 2291: 2285: 2283: 2279: 2278: 2276: 2275: 2270: 2265: 2260: 2255: 2250: 2245: 2240: 2235: 2230: 2225: 2219: 2217: 2208: 2204: 2203: 2198: 2197: 2190: 2183: 2175: 2166: 2165: 2162: 2161: 2149: 2148: 2146: 2142: 2141: 2138: 2137: 2126: 2115: 2104: 2093: 2078: 2062: 2057: 2056: 2054: 2053:Classification 2046: 2045:External links 2043: 2041: 2040: 2005: 1976: 1939: 1933: 1919: 1917: 1914: 1911: 1910: 1899: 1896:on 2012-12-12. 1878: 1871: 1853: 1827: 1824:on 2010-01-02. 1805: 1798:. 2013-05-30. 1781: 1740: 1711:(2): 434–435. 1691: 1642: 1621:(1): 208–212. 1596: 1569:(4): 431–438. 1548: 1499: 1474: 1420: 1391:(1): 173–180. 1371: 1322: 1315: 1297: 1278:(3): 350–355. 1262: 1226: 1220:978-1451172683 1219: 1201: 1166:(4): 431–438. 1143: 1121:2027.42/141823 1084: 1043: 1016:(3): 255–267. 1000: 988:www.cancer.gov 975: 943: 886: 861: 836: 774: 732: 718:2027.42/151292 678: 657:(4): 209–223. 632: 614: 613: 611: 608: 607: 606: 601: 596: 591: 586: 581: 576: 569: 566: 549: 546: 542:Paul Eddington 529:In 1995 actor 526: 523: 521: 518: 495: 492: 486: 483: 462: 459: 440:SĂ©zary disease 379:chemotherapies 352: 349: 327: 324: 305: 304: 301: 298: 292: 285: 265: 262: 236: 233: 198: 195: 112: 109: 69: 68: 55: 49: 48: 44: 43: 35: 34: 31: 27: 26: 18: 15: 9: 6: 4: 3: 2: 4256: 4245: 4242: 4240: 4237: 4235: 4232: 4231: 4229: 4214: 4211: 4209: 4206: 4204: 4201: 4199: 4196: 4194: 4191: 4190: 4188: 4184: 4178: 4175: 4171: 4168: 4166: 4163: 4162: 4161: 4158: 4157: 4155: 4153: 4149: 4139: 4136: 4134: 4131: 4128: 4125: 4123: 4119: 4116: 4115: 4113: 4111: 4110:Lymphocytosis 4107: 4101: 4098: 4097: 4095: 4089: 4079: 4076: 4073: 4069: 4065: 4064: 4060: 4059: 4057: 4053: 4047: 4044: 4042: 4039: 4038: 4036: 4033: 4027: 4023: 4012: 4008: 4007: 4003: 4002: 4000: 3996: 3990: 3987: 3984: 3980: 3977: 3975: 3972: 3970: 3967: 3965: 3964:Hepatosplenic 3962: 3961: 3959: 3957: 3951: 3941: 3938: 3936: 3933: 3931: 3927: 3924: 3923: 3920: 3917: 3915: 3912: 3910: 3906: 3903: 3902: 3900: 3896: 3890: 3887: 3886: 3885: 3884: 3881: 3875: 3872: 3870: 3867: 3865: 3862: 3859: 3858: 3856: 3854: 3850: 3847: 3845: 3841: 3834: 3831: 3829: 3825: 3824: 3820: 3819: 3815: 3811: 3810: 3809:prolymphocyte 3806: 3805: 3802: 3798: 3794: 3791: 3789: 3781: 3778: 3773: 3770: 3768: 3765: 3764: 3763: 3757: 3752: 3747: 3743: 3740: 3738: 3734: 3724: 3721: 3719: 3718:Plasmacytosis 3716: 3714: 3711: 3709: 3706: 3704: 3701: 3699: 3696: 3694: 3691: 3690: 3688: 3686: 3682: 3675: 3674:MALT lymphoma 3671: 3670: 3666: 3663: 3659: 3658: 3654: 3650: 3647: 3646: 3645: 3644: 3640: 3636: 3633: 3631: 3628: 3626: 3623: 3621: 3618: 3617: 3616: 3615: 3611: 3608: 3604: 3603: 3599: 3598: 3596: 3592: 3582: 3581: 3576: 3575: 3573: 3570: 3566: 3561: 3557: 3553: 3546: 3542: 3541: 3537: 3534: 3530: 3527: 3526: 3524: 3521: 3517: 3513: 3509: 3502: 3499: 3497: 3494: 3492: 3489: 3487: 3483: 3482: 3478: 3477:marginal zone 3474: 3473: 3469: 3466: 3464: 3461: 3459: 3456: 3454: 3450: 3449: 3445: 3441: 3440: 3438: 3435: 3431: 3424: 3420: 3419: 3415: 3413: 3410: 3409: 3407: 3404: 3400: 3393: 3389: 3388: 3384: 3381: 3377: 3376: 3372: 3371: 3369: 3366: 3362: 3356: 3352: 3349: 3347: 3345: 3341: 3338: 3330: 3327: 3322: 3319: 3318: 3317: 3311: 3306: 3301: 3297: 3293: 3288: 3284: 3277: 3272: 3270: 3265: 3263: 3258: 3257: 3254: 3238: 3235: 3233: 3230: 3228: 3225: 3223: 3220: 3218: 3215: 3213: 3210: 3208: 3205: 3203: 3200: 3198: 3195: 3193: 3192:Lichen planus 3190: 3188: 3185: 3183: 3180: 3179: 3177: 3175: 3169: 3163: 3160: 3158: 3155: 3153: 3150: 3148: 3147:Onychomycosis 3145: 3144: 3142: 3140: 3136: 3130: 3127: 3125: 3122: 3120: 3117: 3115: 3112: 3110: 3109:Tinea capitis 3107: 3105: 3102: 3100: 3097: 3095: 3092: 3090: 3087: 3086: 3084: 3080: 3074: 3073: 3071: 3069: 3065: 3062: 3058:Miscellaneous 3056: 3042: 3039: 3037: 3034: 3032: 3029: 3027: 3023: 3020: 3019: 3017: 3013: 2999: 2996: 2994: 2991: 2990: 2988: 2984: 2978: 2975: 2973: 2970: 2969: 2967: 2963: 2960: 2956:Nonblanchable 2954: 2943: 2940: 2938: 2935: 2933: 2930: 2928: 2925: 2923: 2919: 2917: 2914: 2913: 2911: 2907: 2901: 2898: 2896: 2893: 2891: 2888: 2886: 2883: 2881: 2878: 2876: 2873: 2872: 2870: 2866: 2860: 2857: 2855: 2852: 2850: 2847: 2845: 2842: 2841: 2839: 2835: 2832: 2830: 2824: 2821: 2817: 2814: 2806: 2796: 2793: 2791: 2788: 2786: 2783: 2781: 2778: 2776: 2773: 2771: 2768: 2766: 2763: 2761: 2758: 2757: 2755: 2753:Hypopigmented 2751: 2745: 2742: 2740: 2737: 2735: 2732: 2730: 2727: 2725: 2722: 2720: 2717: 2715: 2712: 2710: 2707: 2705: 2704:Acne vulgaris 2702: 2701: 2699: 2697: 2693: 2687: 2684: 2682: 2679: 2677: 2674: 2672: 2669: 2667: 2664: 2662: 2659: 2657: 2656:Lichen planus 2654: 2652: 2649: 2647: 2644: 2643: 2641: 2639: 2635: 2629: 2626: 2624: 2621: 2619: 2616: 2614: 2611: 2609: 2606: 2604: 2601: 2599: 2596: 2594: 2591: 2589: 2588:Herpes zoster 2586: 2584: 2581: 2580: 2578: 2576: 2572: 2566: 2563: 2561: 2560:Parapsoriasis 2558: 2556: 2553: 2551: 2548: 2546: 2543: 2541: 2538: 2536: 2533: 2530: 2527: 2525: 2522: 2520: 2517: 2515: 2512: 2510: 2506: 2504: 2501: 2500: 2498: 2496: 2492: 2486: 2483: 2481: 2478: 2476: 2473: 2471: 2468: 2466: 2463: 2461: 2458: 2456: 2453: 2451: 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299: 296: 293: 290: 286: 283: 282: 281: 279: 270: 261: 258: 254: 250: 249:lichen planus 246: 242: 232: 230: 226: 223: 218: 216: 212: 208: 204: 203:T-lymphocytes 194: 192: 187: 185: 181: 177: 172: 170: 164: 156: 150: 146: 142: 138: 134: 133:Penn Medicine 130: 125: 117: 108: 106: 102: 98: 94: 89: 87: 83: 79: 75: 67: 63: 59: 56: 54: 50: 45: 41: 36: 32: 28: 23: 4061: 4004: 3998:By infection 3879: 3878: 3863: 3860: 3852: 3821: 3807: 3785:development/ 3713:Plasmacytoma 3667: 3655: 3641: 3612: 3600: 3594:By infection 3577: 3538: 3475: 3442: 3416: 3385: 3375:naive B cell 3373: 3334:development/ 3162:Ingrown nail 2794: 2734:Dermatophyte 2729:Gonococcemia 2714:Folliculitis 2544: 2355:Neurofibroma 2323:subcutaneous 2152: 2128: 2117: 2106: 2095: 2080: 2065: 2017: 2013: 1984: 1980: 1947: 1943: 1924: 1902: 1894:the original 1888: 1881: 1862: 1856: 1841: 1830: 1822:the original 1817: 1808: 1793: 1784: 1757: 1753: 1743: 1708: 1704: 1694: 1659: 1655: 1645: 1618: 1614: 1566: 1562: 1516: 1512: 1502: 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The name 551: 539: 528: 505:erythroderma 497: 494:Epidemiology 488: 464: 453:or PUVA and 444: 383:radiotherapy 361: 357:PUVA therapy 354: 345: 341: 333: 329: 317: 306: 294: 275: 238: 219: 200: 188: 176:erythroderma 173: 165: 161: 137:Philadelphia 105:radiotherapy 101:chemotherapy 90: 81: 77: 73: 72: 3880:aggressive: 3853:MF+variants 3392:Mantle cell 3387:mantle zone 3217:Herpesvirus 3197:Leukoplakia 3022:Scleroderma 2909:Specialized 2837:Generalized 2812:involvement 2724:Candidiasis 2416:involvement 2390:Myxoid cyst 2238:Acrochordon 1519:(1): 1–11. 755:(1): 2–10. 473:with UV-A, 406:interferons 364:ultraviolet 211:lymph nodes 139:, and then 58:Dermatology 30:Other names 4228:Categories 3956:peripheral 3453:Follicular 3283:Leukaemias 3157:Paronychia 2998:Vasculitis 2922:Multiforme 2920:Erythema ( 2875:Cellulitis 2826:Blanchable 2575:Blistering 2565:Ichthyosis 2423:Eczematous 2335:Hemangioma 2130:DiseasesDB 1493:2010-11-30 1256:2021-11-29 1243:StatPearls 994:2021-11-29 970:2021-11-29 957:StatPearls 880:2021-11-29 856:2021-11-29 610:References 479:bexarotene 477:, or oral 455:bexarotene 390:vorinostat 95:, topical 62:Hematology 4244:Syndromes 4091:Lymphoid+ 3861:indolent: 3844:Cutaneous 3685:Cutaneous 3463:GCB DLBCL 3458:Burkitt's 3287:lymphomas 3152:Psoriasis 3060:disorders 3015:Indurated 2916:Urticaria 2868:Localized 2810:epidermal 2593:Varicella 2503:Psoriasis 2414:epidermal 2380:Leiomyoma 2282:Pigmented 2215:Epidermal 2154:eMedicine 1972:205950255 1591:232103411 1196:232103411 1180:2168-6084 938:236637083 673:1865-5785 535:remission 513:incidence 485:Prognosis 402:retinoids 351:Treatment 289:epidermis 264:Histology 245:psoriasis 235:Diagnosis 207:epidermis 149:Allentown 141:radiation 129:imiquimod 53:Specialty 4239:Lymphoma 4198:leukemia 3756:leukemia 3751:lymphoma 3310:leukemia 3305:lymphoma 3227:Syphilis 3174:membrane 2829:Erythema 2765:Vitiligo 2719:Impetigo 2696:Pustular 2661:Miliaria 2509:Corporis 2360:Xanthoma 2309:Melanoma 2289:Freckles 2159:med/1541 2036:17540844 2001:18086343 1964:18342689 1848:Archived 1800:Archived 1776:24005876 1735:33690948 1686:32141115 1583:33656521 1543:20465602 1469:32982179 1415:29067616 1366:24438970 1292:33769436 1251:30137856 1188:33656521 1138:24447286 1130:28872191 1079:27782301 1038:81927761 1030:31178107 965:32965972 930:34331819 831:32632956 769:29719014 727:31313347 568:See also 471:Psoralen 461:Children 418:naloxone 412:granted 375:steroids 253:vitiligo 180:pruritus 66:Oncology 4186:General 4093:myeloid 4055:T or NK 4026:NK cell 3380:CLL/SLL 3026:morphea 2986:Papular 2965:Macular 2958:Purpura 2942:Ab igne 2927:Migrans 2880:Abscess 2808:Without 2790:Leprosy 2709:Rosacea 2646:Scabies 2638:Papular 2507:Tinea ( 2495:Scaling 2299:Melasma 2294:Lentigo 2207:Growths 2124:D009182 2102:M9700/3 1795:YouTube 1726:8453738 1677:7733543 1637:9921994 1534:2871329 1460:7502391 1406:5756569 921:9291074 875:DynaMed 822:7389258 624:synd/98 548:History 501:tumours 372:topical 366:light ( 326:Staging 313:plaques 225:T cells 184:Itching 4030:(most 4006:HTLV-1 3898:Non-MF 3787:marker 3760:(most 3746:T cell 3418:CD11c+ 3336:marker 3314:(most 3300:B cell 3172:Mucous 3068:Ulcers 2529:Faciei 2524:Manuum 2514:Cruris 2404:Rashes 2350:Lipoma 2345:Keloid 2319:Dermal 2228:Callus 2113:254400 2034:  1999:  1970:  1962:  1944:Lancet 1931:  1869:  1774:  1733:  1723:  1684:  1674:  1635:  1615:Cancer 1589:  1581:  1541:  1531:  1467:  1457:  1413:  1403:  1364:  1313:  1290:  1249:  1217:  1194:  1186:  1178:  1136:  1128:  1077:  1036:  1028:  963:  936:  928:  918:  829:  819:  767:  725:  671:  385:, the 278:biopsy 241:eczema 103:, and 3953:Other 3823:CD30+ 3569:CD138 3540:CD20+ 3434:CD79a 2519:Pedis 2304:Nevus 2097:ICD-O 2091:202.1 2076:C84.0 2014:Blood 1968:S2CID 1587:S2CID 1192:S2CID 1134:S2CID 1034:S2CID 934:S2CID 531:Mr. T 451:IFN-α 431:is a 309:stage 257:lupus 197:Cause 4032:CD56 3926:CD30 3905:CD30 3793:TdT+ 3737:T/NK 3602:KSHV 3578:see 3565:CD38 3556:PCDs 3520:CD30 3516:CD15 3491:MALT 3403:CD22 3344:TdT+ 3321:CD20 3316:CD19 3139:Nail 3082:Hair 2885:Boil 2412:With 2223:Wart 2135:8595 2119:MeSH 2108:OMIM 2086:9-CM 2032:PMID 1997:PMID 1960:PMID 1929:ISBN 1867:ISBN 1772:PMID 1731:PMID 1682:PMID 1633:PMID 1579:PMID 1539:PMID 1465:PMID 1411:PMID 1362:PMID 1311:ISBN 1288:PMID 1247:PMID 1215:ISBN 1184:PMID 1176:ISSN 1126:PMID 1075:PMID 1026:PMID 961:PMID 926:PMID 827:PMID 805:2020 765:PMID 723:PMID 669:ISSN 433:CCR4 416:for 4063:EBV 3928:+: 3907:-: 3797:ALL 3772:CD8 3767:CD4 3762:CD3 3657:HIV 3643:HCV 3614:EBV 3518:+, 3365:CD5 3351:ALL 2819:Red 2321:and 2082:ICD 2067:ICD 2022:doi 2018:110 1989:doi 1952:doi 1948:371 1762:doi 1758:149 1721:PMC 1713:doi 1709:185 1672:PMC 1664:doi 1623:doi 1571:doi 1567:157 1529:PMC 1521:doi 1455:PMC 1445:doi 1401:PMC 1393:doi 1354:doi 1280:doi 1276:156 1168:doi 1164:157 1116:hdl 1106:doi 1065:doi 1061:176 1018:doi 916:PMC 908:doi 817:PMC 809:doi 757:doi 713:hdl 703:doi 659:doi 627:at 370:), 307:To 222:CD4 147:in 143:at 135:in 131:at 80:or 4230:: 3795:: 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Index


Specialty
Dermatology
Hematology
Oncology
cutaneous T-cell lymphoma
ultraviolet light
corticosteroids
chemotherapy
radiotherapy


imiquimod
Penn Medicine
Philadelphia
radiation
Lehigh Valley Hospital–Cedar Crest
Allentown

Hypopigmentation
erythroderma
pruritus
Itching
SĂ©zary syndrome
T-lymphocytes
epidermis
lymph nodes
programmed cell death
CD4
T cells

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