242:
219:
141:
116:
248:
147:
1776:
255:
154:
1018:
that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
77:
682:
663:
1165:
Rousseau K, Byrne C, Kim YS, Gum JR, Swallow DM, Toribara NW (May 2004). "The complete genomic organization of the human MUC6 and MUC2 mucin genes".
1109:
1091:
1029:
885:
878:
1231:
1200:
1817:
1836:
1074:
1608:
1053:
1648:
241:
1498:
1078:
1057:
995:
218:
727:
140:
115:
708:
1209:
57:
1745:
1224:
1810:
1735:
254:
153:
1698:
1658:
247:
146:
44:
1638:
1613:
65:
998:
to the mucin proteins. This gel provides an insoluble mucous barrier that serves to protect the
842:
816:
795:
1846:
1673:
1217:
1130:
Allen A, Hutton DA, Pearson JP (July 1998). "The MUC2 gene product: a human intestinal mucin".
1803:
999:
129:
85:
8:
1678:
1603:
1490:
1467:
1431:
1403:
967:
protein family. The protein encoded by this gene, also called mucin 2, is secreted onto
1628:
89:
1143:
597:
592:
587:
571:
566:
561:
556:
551:
546:
541:
525:
1703:
1532:
1182:
1147:
37:
69:
1618:
1435:
1388:
1174:
1139:
334:
265:
209:
164:
1841:
1791:
1575:
1547:
1463:
991:
983:
309:
93:
1178:
1114:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1096:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1010:
The mucin 2 protein features a central domain containing tandem repeats rich in
1787:
1725:
1244:
410:
1830:
1730:
1718:
1398:
1033:
512:
1239:
470:
348:
1643:
1555:
1422:
1252:
1248:
1186:
975:
327:
106:
1151:
925:
920:
1755:
1750:
1740:
1713:
1683:
1668:
1537:
1393:
1383:
1260:
753:
1583:
987:
979:
974:
Mucin 2 is particularly prominent in the gut where it is secreted from
226:
123:
73:
986:. There, mucin 2, along with small amounts of related-mucin proteins,
1693:
1688:
1663:
1653:
1565:
1011:
627:
293:
280:
192:
179:
81:
1512:
1507:
1502:
1480:
1475:
1453:
1448:
1408:
909:
1783:
1560:
1443:
1240:
1015:
968:
945:
739:
694:
612:
608:
61:
1633:
1352:
1312:
893:
649:
1527:
1522:
1367:
1362:
1357:
1347:
1342:
1337:
1317:
1302:
1297:
1282:
1269:
964:
1775:
1708:
1623:
1517:
1332:
1327:
1322:
1307:
1292:
1287:
1277:
952:
1201:"Entrez Gene: MUC2 mucin 2, oligomeric mucus/gel-forming"
48:, MLP, MUC-2, SMUC, mucin 2, oligomeric mucus/gel-forming
317:
482:
598:
stimulatory C-type lectin receptor signaling pathway
1164:
1129:
1070:
1068:
1066:
1049:
1047:
1045:
264:
163:
1828:
1063:
1042:
16:Protein-coding gene in the species Homo sapiens
1075:GRCm38: Ensembl release 89: ENSMUSG00000025515
940:, oligomeric mucus gel-forming, also known as
1811:
1225:
1125:
1123:
1158:
1054:GRCh38: Ensembl release 89: ENSG00000198788
1818:
1804:
1232:
1218:
1120:
1030:United States National Library of Medicine
593:maintenance of gastrointestinal epithelium
1028:This article incorporates text from the
572:collagen-containing extracellular matrix
1538:Structural maintenance of chromosomes 3
1829:
1213:
990:into a gel of which 80% by weight is
269:
230:
225:
168:
127:
122:
1770:
13:
963:This gene encodes a member of the
14:
1858:
1649:Cholesterylester transfer protein
1499:Chondroitin sulfate proteoglycans
948:that in humans is encoded by the
1774:
996:post-translational modifications
253:
246:
240:
217:
152:
145:
139:
114:
1193:
1102:
1084:
994:side-chains that are added as
471:More reference expression data
383:olfactory zone of nasal mucosa
1:
1144:10.1016/S1357-2725(98)00028-4
1021:
387:muscle layer of sigmoid colon
238:
137:
1837:Genes on human chromosome 11
1790:. You can help Knowledge by
7:
1746:Tumor necrosis factor alpha
1179:10.1016/j.ygeno.2003.11.003
1005:
958:
10:
1863:
1769:
1736:Thyroxine-binding proteins
1132:Int. J. Biochem. Cell Biol
359:mucosa of transverse colon
1699:Serum amyloid P component
1659:Colony-stimulating factor
1596:
1574:
1546:
1489:
1462:
1430:
1421:
1376:
1268:
1259:
1110:"Mouse PubMed Reference:"
1092:"Human PubMed Reference:"
924:
919:
915:
908:
892:
886:Chr 7: 141.28 – 141.31 Mb
873:
860:
856:
839:
835:
828:
813:
809:
792:
788:
781:
770:
766:
751:
747:
738:
725:
721:
706:
702:
693:
680:
676:
661:
657:
648:
633:
626:
622:
606:
511:
507:
495:
490:
481:
468:
417:
408:
355:
346:
316:
308:
304:
287:
274:
237:
216:
207:
203:
186:
173:
136:
113:
104:
100:
55:
52:
42:
35:
30:
26:
21:
1639:B-cell activating factor
1614:Alpha 1-antichymotrypsin
1786:-related article is a
1674:Membrane glycoproteins
982:into the lumen of the
879:Chr 11: 1.07 – 1.11 Mb
437:neural layer of retina
1000:intestinal epithelium
391:right coronary artery
130:Chromosome 11 (human)
542:extracellular region
379:smooth muscle tissue
232:Chromosome 7 (mouse)
1679:Myelin protein zero
1604:Activin and inhibin
1404:Phytohaemagglutinin
588:O-glycan processing
375:epithelium of colon
271:7 F5|7 87.1 cM
1629:Asialoglycoprotein
1032:, which is in the
728:ENSMUSG00000025515
581:Biological process
535:Cellular component
519:Molecular function
1799:
1798:
1764:
1763:
1704:Sialoglycoprotein
1592:
1591:
1533:Platelet factor 4
1417:
1416:
980:epithelial lining
935:
934:
931:
930:
904:
903:
869:
868:
850:
849:
824:
823:
803:
802:
777:
776:
760:
759:
734:
733:
715:
714:
689:
688:
670:
669:
618:
617:
557:inner mucus layer
547:outer mucus layer
503:
502:
499:
498:
477:
476:
464:
463:
402:
401:
300:
299:
199:
198:
1854:
1820:
1813:
1806:
1778:
1771:
1619:Apolipoprotein H
1428:
1427:
1389:Intrinsic factor
1266:
1265:
1234:
1227:
1220:
1211:
1210:
1205:
1204:
1197:
1191:
1190:
1162:
1156:
1155:
1127:
1118:
1117:
1106:
1100:
1099:
1088:
1082:
1072:
1061:
1051:
969:mucosal surfaces
917:
916:
888:
881:
864:
854:
853:
845:
833:
832:
829:RefSeq (protein)
819:
807:
806:
798:
786:
785:
764:
763:
745:
744:
719:
718:
700:
699:
674:
673:
655:
654:
624:
623:
509:
508:
488:
487:
473:
413:
411:Top expressed in
406:
405:
351:
349:Top expressed in
344:
343:
323:
322:
306:
305:
296:
283:
272:
257:
250:
244:
233:
221:
205:
204:
195:
182:
171:
156:
149:
143:
132:
118:
102:
101:
96:
94:MUC2 - orthologs
47:
40:
19:
18:
1862:
1861:
1857:
1856:
1855:
1853:
1852:
1851:
1827:
1826:
1825:
1824:
1767:
1765:
1760:
1588:
1570:
1542:
1485:
1458:
1413:
1372:
1255:
1238:
1208:
1199:
1198:
1194:
1163:
1159:
1128:
1121:
1108:
1107:
1103:
1090:
1089:
1085:
1073:
1064:
1052:
1043:
1024:
1008:
992:oligosaccharide
984:large intestine
961:
926:View/Edit Mouse
921:View/Edit Human
884:
877:
874:Location (UCSC)
862:
841:
815:
794:
709:ENSG00000198788
602:
576:
567:plasma membrane
530:
526:protein binding
469:
460:
455:
451:
447:
443:
441:urinary bladder
439:
435:
431:
427:
423:
409:
398:
395:urinary bladder
393:
389:
385:
381:
377:
373:
369:
365:
361:
347:
291:
278:
270:
260:
259:
258:
251:
231:
208:Gene location (
190:
177:
169:
159:
158:
157:
150:
128:
105:Gene location (
56:
43:
36:
17:
12:
11:
5:
1860:
1850:
1849:
1844:
1839:
1823:
1822:
1815:
1808:
1800:
1797:
1796:
1779:
1762:
1761:
1759:
1758:
1753:
1748:
1743:
1738:
1733:
1728:
1726:Thrombopoietin
1723:
1722:
1721:
1716:
1711:
1701:
1696:
1691:
1686:
1681:
1676:
1671:
1666:
1661:
1656:
1651:
1646:
1641:
1636:
1631:
1626:
1621:
1616:
1611:
1606:
1600:
1598:
1594:
1593:
1590:
1589:
1587:
1586:
1580:
1578:
1572:
1571:
1569:
1568:
1563:
1558:
1552:
1550:
1544:
1543:
1541:
1540:
1535:
1530:
1525:
1520:
1515:
1510:
1505:
1495:
1493:
1487:
1486:
1484:
1483:
1478:
1472:
1470:
1460:
1459:
1457:
1456:
1451:
1446:
1440:
1438:
1425:
1419:
1418:
1415:
1414:
1412:
1411:
1406:
1401:
1396:
1391:
1386:
1380:
1378:
1374:
1373:
1371:
1370:
1365:
1360:
1355:
1350:
1345:
1340:
1335:
1330:
1325:
1320:
1315:
1310:
1305:
1300:
1295:
1290:
1285:
1280:
1274:
1272:
1263:
1257:
1256:
1245:glycoconjugate
1237:
1236:
1229:
1222:
1214:
1207:
1206:
1192:
1157:
1138:(7): 797–801.
1119:
1101:
1083:
1062:
1040:
1039:
1038:
1023:
1020:
1007:
1004:
960:
957:
933:
932:
929:
928:
923:
913:
912:
906:
905:
902:
901:
899:
897:
890:
889:
882:
875:
871:
870:
867:
866:
858:
857:
851:
848:
847:
837:
836:
830:
826:
825:
822:
821:
811:
810:
804:
801:
800:
790:
789:
783:
779:
778:
775:
774:
768:
767:
761:
758:
757:
749:
748:
742:
736:
735:
732:
731:
723:
722:
716:
713:
712:
704:
703:
697:
691:
690:
687:
686:
678:
677:
671:
668:
667:
659:
658:
652:
646:
645:
640:
635:
631:
630:
620:
619:
616:
615:
604:
603:
601:
600:
595:
590:
584:
582:
578:
577:
575:
574:
569:
564:
559:
554:
549:
544:
538:
536:
532:
531:
529:
528:
522:
520:
516:
515:
505:
504:
501:
500:
497:
496:
493:
492:
485:
479:
478:
475:
474:
466:
465:
462:
461:
459:
458:
454:
450:
449:tail of embryo
446:
442:
438:
434:
430:
426:
422:
418:
415:
414:
403:
400:
399:
397:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
356:
353:
352:
340:
339:
331:
320:
314:
313:
310:RNA expression
302:
301:
298:
297:
289:
285:
284:
276:
273:
268:
262:
261:
252:
245:
239:
235:
234:
229:
223:
222:
214:
213:
201:
200:
197:
196:
188:
184:
183:
175:
172:
167:
161:
160:
151:
144:
138:
134:
133:
126:
120:
119:
111:
110:
98:
97:
54:
50:
49:
41:
33:
32:
28:
27:
24:
23:
15:
9:
6:
4:
3:
2:
1859:
1848:
1847:Protein stubs
1845:
1843:
1840:
1838:
1835:
1834:
1832:
1821:
1816:
1814:
1809:
1807:
1802:
1801:
1795:
1793:
1789:
1785:
1780:
1777:
1773:
1772:
1768:
1757:
1754:
1752:
1749:
1747:
1744:
1742:
1739:
1737:
1734:
1732:
1731:Thyroglobulin
1729:
1727:
1724:
1720:
1719:Glycophorin C
1717:
1715:
1712:
1710:
1707:
1706:
1705:
1702:
1700:
1697:
1695:
1692:
1690:
1687:
1685:
1682:
1680:
1677:
1675:
1672:
1670:
1667:
1665:
1662:
1660:
1657:
1655:
1652:
1650:
1647:
1645:
1642:
1640:
1637:
1635:
1632:
1630:
1627:
1625:
1622:
1620:
1617:
1615:
1612:
1610:
1607:
1605:
1602:
1601:
1599:
1595:
1585:
1582:
1581:
1579:
1577:
1573:
1567:
1564:
1562:
1559:
1557:
1554:
1553:
1551:
1549:
1545:
1539:
1536:
1534:
1531:
1529:
1526:
1524:
1521:
1519:
1516:
1514:
1511:
1509:
1506:
1504:
1500:
1497:
1496:
1494:
1492:
1488:
1482:
1479:
1477:
1474:
1473:
1471:
1469:
1465:
1461:
1455:
1452:
1450:
1447:
1445:
1442:
1441:
1439:
1437:
1433:
1429:
1426:
1424:
1423:Proteoglycans
1420:
1410:
1407:
1405:
1402:
1400:
1399:Peptidoglycan
1397:
1395:
1392:
1390:
1387:
1385:
1382:
1381:
1379:
1375:
1369:
1366:
1364:
1361:
1359:
1356:
1354:
1351:
1349:
1346:
1344:
1341:
1339:
1336:
1334:
1331:
1329:
1326:
1324:
1321:
1319:
1316:
1314:
1311:
1309:
1306:
1304:
1301:
1299:
1296:
1294:
1291:
1289:
1286:
1284:
1281:
1279:
1276:
1275:
1273:
1271:
1267:
1264:
1262:
1258:
1254:
1253:glycopeptides
1250:
1249:glycoproteins
1246:
1242:
1235:
1230:
1228:
1223:
1221:
1216:
1215:
1212:
1202:
1196:
1188:
1184:
1180:
1176:
1172:
1168:
1161:
1153:
1149:
1145:
1141:
1137:
1133:
1126:
1124:
1115:
1111:
1105:
1097:
1093:
1087:
1080:
1076:
1071:
1069:
1067:
1059:
1055:
1050:
1048:
1046:
1041:
1037:
1035:
1034:public domain
1031:
1026:
1025:
1019:
1017:
1013:
1003:
1001:
997:
993:
989:
985:
981:
977:
972:
970:
966:
956:
954:
951:
947:
943:
939:
927:
922:
918:
914:
911:
907:
900:
898:
895:
891:
887:
883:
880:
876:
872:
865:
859:
855:
852:
846:
844:
838:
834:
831:
827:
820:
818:
812:
808:
805:
799:
797:
791:
787:
784:
782:RefSeq (mRNA)
780:
773:
769:
765:
762:
756:
755:
750:
746:
743:
741:
737:
730:
729:
724:
720:
717:
711:
710:
705:
701:
698:
696:
692:
685:
684:
679:
675:
672:
666:
665:
660:
656:
653:
651:
647:
644:
641:
639:
636:
632:
629:
625:
621:
614:
610:
605:
599:
596:
594:
591:
589:
586:
585:
583:
580:
579:
573:
570:
568:
565:
563:
560:
558:
555:
553:
550:
548:
545:
543:
540:
539:
537:
534:
533:
527:
524:
523:
521:
518:
517:
514:
513:Gene ontology
510:
506:
494:
489:
486:
484:
480:
472:
467:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
419:
416:
412:
407:
404:
394:
390:
386:
382:
378:
374:
370:
366:
362:
358:
357:
354:
350:
345:
342:
341:
338:
336:
332:
330:
329:
325:
324:
321:
319:
315:
311:
307:
303:
295:
290:
286:
282:
277:
267:
263:
256:
249:
243:
236:
228:
224:
220:
215:
211:
206:
202:
194:
189:
185:
181:
176:
166:
162:
155:
148:
142:
135:
131:
125:
121:
117:
112:
108:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
59:
51:
46:
39:
34:
29:
25:
20:
1792:expanding it
1781:
1766:
1644:4-1BB ligand
1556:Fibromodulin
1261:Mucoproteins
1195:
1173:(5): 936–9.
1170:
1166:
1160:
1135:
1131:
1113:
1104:
1095:
1086:
1027:
1009:
976:goblet cells
973:
962:
949:
941:
937:
936:
861:
840:
814:
793:
771:
752:
726:
707:
681:
662:
642:
637:
333:
326:
292:141,308,430
279:141,276,583
53:External IDs
1756:Vitronectin
1751:Uteroglobin
1741:Transcortin
1714:Glycophorin
1684:Osteonectin
1669:Lactoferrin
1394:Orosomucoid
1384:Haptoglobin
988:polymerizes
562:mucus layer
552:Golgi lumen
31:Identifiers
1831:Categories
1584:Syndecan 1
1081:, May 2017
1060:, May 2017
1022:References
337:(ortholog)
191:1,110,511
178:1,074,875
74:HomoloGene
1694:Protein S
1689:Protein C
1664:Hemopexin
1654:Clusterin
1566:Keratocan
1012:threonine
843:NP_002448
817:NM_023566
796:NM_002457
628:Orthologs
82:GeneCards
1513:Brevican
1508:Neurocan
1503:Aggrecan
1481:Perlecan
1476:Testican
1454:Versican
1449:Biglycan
1409:Ovomucin
1187:15081123
1167:Genomics
1077:–
1056:–
1006:Genetics
959:Function
910:Wikidata
607:Sources:
433:duodenum
371:appendix
367:duodenum
1784:protein
1561:Lumican
1444:Decorin
1241:Protein
1152:9722984
1079:Ensembl
1058:Ensembl
1016:proline
978:in the
946:protein
944:, is a
938:Mucin 2
740:UniProt
695:Ensembl
634:Species
613:QuickGO
421:jejunum
312:pattern
170:11p15.5
70:1339364
38:Aliases
1842:Mucins
1634:Avidin
1313:MUC5AC
1185:
1150:
896:search
894:PubMed
754:Q02817
650:Entrez
483:BioGPS
457:embryo
453:embryo
445:zygote
363:rectum
78:136755
62:158370
1782:This
1597:Other
1528:CSPG5
1523:CSPG4
1377:Other
1368:MUC20
1363:MUC19
1358:MUC17
1353:MUC16
1348:MUC15
1343:MUC13
1338:MUC12
1318:MUC5B
1303:MUC3B
1298:MUC3A
1283:CD164
1270:Mucin
965:mucin
683:17831
643:Mouse
638:Human
609:Amigo
429:ileum
425:colon
335:Mouse
328:Human
275:Start
210:Mouse
174:Start
107:Human
1788:stub
1709:CD43
1624:CD70
1609:ADAM
1518:CD44
1333:MUC8
1328:MUC7
1323:MUC6
1308:MUC4
1293:MUC2
1288:MUC1
1278:CD43
1251:and
1183:PMID
1148:PMID
1014:and
953:gene
950:MUC2
942:MUC2
664:4583
318:Bgee
266:Band
227:Chr.
165:Band
124:Chr.
86:MUC2
58:OMIM
45:MUC2
22:MUC2
1175:doi
1140:doi
863:n/a
772:n/a
491:n/a
288:End
187:End
90:OMA
66:MGI
1833::
1576:HS
1548:KS
1501::
1491:CS
1468:CS
1464:HS
1436:DS
1432:CS
1247::
1243:,
1181:.
1171:83
1169:.
1146:.
1136:30
1134:.
1122:^
1112:.
1094:.
1065:^
1044:^
1002:.
971:.
955:.
611:/
294:bp
281:bp
193:bp
180:bp
88:;
84::
80:;
76::
72:;
68::
64:;
60::
1819:e
1812:t
1805:v
1794:.
1466:/
1434:/
1233:e
1226:t
1219:v
1203:.
1189:.
1177::
1154:.
1142::
1116:.
1098:.
1036:.
212:)
109:)
92::
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