Knowledge

Margaret Tisdale

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98:, which Glaxo licensed from Biota in 1990. She established the global Neuraminidase Inhibitor Susceptibility Network in 1999 to track resistance to neuraminidase inhibitors in clinical strains of influenza virus. She also published on antiviral drugs against 126:
M Tisdale, SD Kemp, NR Parry, BA Larder (1993). Rapid in vitro selection of human immunodeficiency virus type 1 resistant to 3'-thiacytidine inhibitors due to a mutation in the YMDD region of reverse transcriptase.
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Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89.
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DJ Bauer; JWT Selway; JF Batchelor; M Tisdale; IC Caldwell; DAB Young (1981), "4′,6-Dichloroflavan (BW683C), a new anti-rhinovirus compound",
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M Tisdale (2000). Monitoring of viral susceptibility: new challenges with the development of influenza NA inhibitors.
325: 370: 345: 73: 340: 330: 335: 92: 85: 355: 350: 245: 66: 65:, Tisdale was educated at Trefnanney School and Welshpool Comprehensive, before attending 8: 294: 81: 249: 266: 271: 137: 27: 261: 253: 236: 209:"Tributes paid to Montgomeryshire scientist Margaret Tisdale who has died, aged 64" 77: 42: 34: 130:
Proceedings of the National Academy of Sciences of the United States of America
110: 31: 80:, where she eventually became head of clinical virology. She was an expert in 314: 114: 290:"Antidepressants can raise the risk of suicide, biggest ever review finds" 275: 103: 233: 99: 257: 95: 89: 62: 50: 46: 179:"Gone in 2015: Commemorating 10 Outstanding Women in Science" 38: 211:. Denbighshire Free Press. 28 May 2015. Archived from 26:; 10 September 1950 – 29 April 2015) was a Welsh-born 45:, and for coordinating the development of the anti- 312: 203: 201: 199: 72:Tisdale spent 33 years as a researcher at the 287: 196: 265: 136:M Tisdale, T Alnadaf, D Cousens (1997). 120: 88:. Tisdale headed the development of the 173: 171: 169: 167: 165: 313: 142:Antimicrobial Agents and Chemotherapy 162: 386:21st-century Welsh women scientists 381:20th-century Welsh women scientists 13: 14: 397: 288:Sarah Knapton (27 January 2016), 183:Scientific American Blog Network 281: 227: 74:Wellcome Research Laboratories 1: 366:21st-century Welsh scientists 361:20th-century Welsh scientists 156: 321:Welsh scholars and academics 56: 7: 150:Reviews in Medical Virology 10: 402: 376:People from Wrestlingworth 30:known for her studies of 16:Welsh Clinical Virologist 93:neuraminidase inhibitor 326:Welsh women scientists 86:antiretroviral therapy 371:People from Welshpool 346:Influenza researchers 121:Selected publications 341:HIV/AIDS researchers 109:She died aged 64 in 76:, GlaxoWellcome and 67:Guildford University 331:British virologists 295:The Daily Telegraph 250:1981Natur.292..369B 102:, which causes the 82:HIV drug resistance 28:clinical virologist 215:on 26 January 2016 84:and in optimising 336:Women virologists 393: 306: 305: 304: 302: 285: 279: 278: 269: 258:10.1038/292369a0 244:(5821): 369–70, 231: 225: 224: 222: 220: 205: 194: 193: 191: 189: 175: 20:Margaret Tisdale 401: 400: 396: 395: 394: 392: 391: 390: 311: 310: 309: 300: 298: 286: 282: 232: 228: 218: 216: 207: 206: 197: 187: 185: 177: 176: 163: 159: 123: 78:GlaxoSmithKline 59: 43:influenza virus 17: 12: 11: 5: 399: 389: 388: 383: 378: 373: 368: 363: 358: 353: 348: 343: 338: 333: 328: 323: 308: 307: 280: 226: 195: 160: 158: 155: 154: 153: 146: 134: 122: 119: 111:Wrestlingworth 58: 55: 15: 9: 6: 4: 3: 2: 398: 387: 384: 382: 379: 377: 374: 372: 369: 367: 364: 362: 359: 357: 354: 352: 349: 347: 344: 342: 339: 337: 334: 332: 329: 327: 324: 322: 319: 318: 316: 297: 296: 291: 284: 277: 273: 268: 263: 259: 255: 251: 247: 243: 239: 238: 230: 214: 210: 204: 202: 200: 184: 180: 174: 172: 170: 168: 166: 161: 151: 147: 144: 143: 139: 135: 132: 131: 125: 124: 118: 116: 112: 107: 105: 101: 97: 94: 91: 87: 83: 79: 75: 70: 68: 64: 54: 52: 48: 44: 40: 36: 33: 29: 25: 21: 299:, retrieved 293: 283: 241: 235: 229: 217:. Retrieved 213:the original 186:. Retrieved 182: 149: 140: 128: 115:Bedfordshire 108: 71: 60: 23: 19: 18: 356:1950 births 351:2015 deaths 145:41: 1094–98 133:90: 5653–56 104:common cold 315:Categories 301:31 January 219:19 January 188:19 January 157:References 100:rhinovirus 35:resistance 152:10: 45–55 96:zanamivir 90:influenza 63:Welshpool 57:Biography 51:zanamivir 47:influenza 32:antiviral 61:Born in 276:6265792 267:7094996 246:Bibcode 274:  264:  237:Nature 24:Breeze 49:drug 22:(nÊe 303:2016 272:PMID 221:2016 190:2016 41:and 262:PMC 254:doi 242:292 39:HIV 37:in 317:: 292:, 270:, 260:, 252:, 240:, 198:^ 181:. 164:^ 117:. 113:, 106:. 69:. 53:. 256:: 248:: 223:. 192:.

Index

clinical virologist
antiviral
resistance
HIV
influenza virus
influenza
zanamivir
Welshpool
Guildford University
Wellcome Research Laboratories
GlaxoSmithKline
HIV drug resistance
antiretroviral therapy
influenza
neuraminidase inhibitor
zanamivir
rhinovirus
common cold
Wrestlingworth
Bedfordshire
Proceedings of the National Academy of Sciences of the United States of America
Combination of mutations in human immunodeficiency virus type 1 reverse transcriptase required for resistance to the carbocyclic nucleoside 1592U89.
Antimicrobial Agents and Chemotherapy





"Gone in 2015: Commemorating 10 Outstanding Women in Science"

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