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History of intersex surgery

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1113:'s tragic story, told in both popular and medical publications, was widely interpreted by the public and many physicians as a cautionary tale of medical hubris, of the folly of attempting to foil nature with nurture, of the importance of early hormones on brain development, and the risks and limitations of surgery. Some clinicians proposed a moratorium on pediatric sex reassignment, particularly of undervirilized males as females, due to a lack of data that rearing or appearance of genitalia play a major part in gender identity development. Those clinicians encouraged delaying surgery until elected by adolescents to preserve sexual sensitivity. 1179:... outcomes from clitoroplasty identify problems related to decreased sexual sensitivity, loss of clitoral tissue, and cosmetic issues ... Feminising as opposed to masculinising genitoplasty requires less surgery to achieve an acceptable outcome and results in fewer urological difficulties... Long term data on sexual function and quality of life among those assigned female as well as male show great variability. There are no controlled clinical trials of the efficacy of early (less than 12 months of age) versus late surgery (in adolescence and adulthood), or of the efficacy of different techniques 657:
rates. Some surgeons, well aware of the immediate limitations and risks of surgery, feel that significant rates of imperfect outcomes are no scandal (especially for the more severe and disabling conditions). Instead they see these negative outcomes as a challenge to be overcome by improving the techniques. Genital reconstruction evolved within this tradition. In recent decades, nearly every aspect of this perspective has been called into question, with increasing concern regarding the
43: 773:. Although it seems obvious now that a doctor could not announce to an eight-year-old boy and his parents that "we have just discovered that you are 'really' a girl, with female chromosomes, and ovaries and uterus inside, and we recommend that you change your sex to match your chromosomes and internal organs," a few such events occurred around the world as doctors and parents tried to make use of new information. 1214:
surgical procedures are sources of concerns. There is no evidence regarding the impact of surgically treated or non-treated DSDs during childhood for the individual, the parents, society or the risk of stigmatization... Physicians working with these families should be aware that the trend in recent years has been for legal and human rights bodies to increasingly emphasize preserving patient autonomy.
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information and counseling) to the radical (assigning a third sex or no sex at all to intersex infants). The idea that possession of abnormal genitalia in and of itself does not constitute a medical crisis was stressed. The claims of advocacy groups have been resisted. In response to a demonstration by members of the Intersex Society of North America outside the annual conference of the
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of parents for an "early fix," and (4) the observation of many surgeons that connective tissue, skin, and organs of infants heal faster, with less scarring than those of adolescents and adults. However, one of the drawbacks of surgery in infancy was that it would be decades before outcomes in terms of adult sexual function and gender identity could be assessed.
1120:'s constitutional court limited the ability of parents to consent to genital surgery for infants with intersex conditions. A number of advocacy groups argue against many forms of genital surgery in childhood. In 2001, British surgeons argued for deferring vaginoplasty until adulthood on grounds of poor outcomes for women who were operated on as infants. 1223:
commentary stated that the purpose of the 2006 Consensus Statement was to validate existing practices, "The authoritativeness and "consensus" in the Chicago statement lies not in comprehensive clinician input or meaningful community input, but in its utility to justify any and all forms of clinical intervention."
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Mouriquand PD, Gorduza DB, Gay CL, Meyer-Bahlburg HF, Baker L, Baskin LS, Bouvattier C, Braga LH, Caldamone AC, Duranteau L, El Ghoneimi A, Hensle TW, Hoebeke P, Kaefer M, Kalfa N, Kolon TF, Manzoni G, Mure PY, Nordenskjöld A, Pippi Salle JL, Poppas DP, Ransley PG, Rink RC, Rodrigo R, Sann L, Schober
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It is generally felt that surgery that is carried out for cosmetic reasons in the first year of life relieves parental distress and improves attachment between the child and the parents. The systematic evidence for this belief is lacking. ... information across a range of assessments is insufficient
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and others examined outcomes from early surgeries in individuals with XY variations, at one patient centre. The study has been used to support claims that "‘the majority of women...have clearly favored genital surgery at an earlier age" but the study was criticized by Baratz and Feder for neglecting
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have attempted to "fix" an increasing variety of conditions. Success has often been partial and surgery is often associated with minor or major, transient or permanent complications. Techniques in all fields of surgery are frequently revised in a quest for higher success rates and lower complication
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Research on children with ambiguous genitalia has shown that a person's sexual body image is largely a function of socialization, and children whose genetic sexes are not clearly reflected in external genitalia can be raised successfully as members of either sexes if the process begins before 2 1/2
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Genital corrective surgeries in infancy were justified by (1) the belief that genital surgery is less emotionally traumatic if performed before the age of long-term memory, (2) the assumption that a firm gender identity would be best supported by genitalia that "looked the part," (3) the preference
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The most common intersex surgery offered in childhood was amputation of the clitoris and widening of the vaginal opening to make the genitals of a girl with CAH appear more conformed to the expectations. However, by the late 1950s surgical techniques for transforming assigned male at birth patients
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There is still no consensual attitude regarding indications, timing, procedure and evaluation of outcome of DSD surgery. The levels of evidence of responses given by the experts are low (B and C), while most are supported by team expertise... Timing, choice of the individual and irreversibility of
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In 2006, an invited group of clinicians met in Chicago and reviewed clinical evidence and protocols, argued that and adopted a new term for intersex conditions: "Disorders of sex development" (DSD). More specifically, these terms refer to "congenital conditions in which development of chromosomal,
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which could be improved with hormones rather than surgery, and over the next decade a couple of reports suggested adult outcome as males was not as bad as expected for the boys with micropenis who had not had surgery. Although textbooks were slower to reflect the change, few reassignment surgeries
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As the number of children with intersex conditions referred to Lawson Wilkins' new pediatric endocrinology clinic at Hopkins increased, it was recognized that doctors "couldn't tell by looking" at the external genitalia, and many errors of diagnosis based on outward appearance had led to anomalous
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Survey of patients treated with older management, including 5 with micropenis reassigned and raised as women. Gender identity was concordant with sex of assignment in all. Women with CAIS were satisfied with genitalia, men and women who had had micropenis were universally dissatisfied, but sexual
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were most uncritically accepted in academic opinion, in most children's hospitals, and by society at large. In this context, enhancing the ability of people born with abnormalities of the genitalia to engage in "normal" heterosexual intercourse as adults assumed increasing importance as a goal of
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and 9% were deceased (2 from suicide). Of the 96 located, eligible adults, 78% consented to participate (18 women born with complete undervirilization, 18 women born with partial undervirilization, 21 men with partial virilization, 5 women born with micropenis, and 13 men born with micropenis).
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In a study in Lübeck conducted between 2005 and 2007 ... 81% of 439 individuals had been subjected to surgeries due to their intersex diagnoses. Almost 50% of participants reported psychological problems. Two thirds of the adult participants drew a connection between sexual problems and their
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Data presented in recent years suggests that little has changed in practice. Creighton and others in the UK have found that there have been few audits of the implementation of the 2006 statement, clitoral surgeries on under-14s have increased since 2006, and "recent publications in the medical
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was the most influential and persistent, and advocated postponing genital surgery until a child is old enough to display a clear gender identity and consent to the surgery. Recommendations from these voices ranged from the unexceptionable (ending shame and secrecy, and providing more accurate
1038:(CAH), and unsatisfactory sexual outcomes in adult women with CAH. Many endocrinologists were becoming skeptical that reassignment of genetic males to females was just a matter of learning and appearance, or that the newer clitoral reductions would be more successful than clitoral recessions. 1222:
and Ellen Feder criticized that omission, stating that issues have barely changed in two decades, with "lack of novel developments", while "lack of evidence appears not to have had much impact on physicians' confidence in a standard of care that has remained largely unchanged." Another 2016
689:(Alexandria, 2nd – 3rd centuries), describes in section LXIX (On Hermaphrodites) of his sixth book four types of intersex and how to "cure" three of them by surgically removing the "useless parts". In the next section (LXX, On Extirpation of the Nympha and Cauda Pudendi) he deals with 1081:
A more abrupt and sweeping re-evaluation of reconstructive genital surgery began about 1993, triggered by a combination of factors. One of the major factors was the rise of patient advocacy groups that expressed dissatisfaction with several aspects of their own past treatments. The
919:, the lessening of many social barriers and inhibitions related to sexual behavior, and social acknowledgment of women's sexuality. In this era, genes and hormones were thought not to have a strong influence on any aspect of human psychosexual development, gender identity, or 2363:
Eight of 14 genetic males who were born with exstrophy and unsalvageable penis, assigned and raised as females, spontaneously reassigned themselves to male sex as they grew up. This outcome suggests XY infants with exstrophy but normal testes should not be raised as
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Restatement of the classic surgeon's arguments that (1) complications are being reduced by newer techniques, and (2) that surgery should optimally be performed even earlier (by 2 months of age) to take advantage of the estrogenized state of the tissue in early
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A 2016 Australian study of persons born with atypical sex characteristics found that "strong evidence suggesting a pattern of institutionalised shaming and coercive treatment of people". Large majorities of respondents opposed standard clinical protocols.
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if surgery were performed later, or (3) that significant technical improvements that were expected to improve outcomes had occurred in the 13 or 14 years between when they underwent early childhood surgery and when it might have been deferred until after
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Lee PA, Nordenström A, Houk CP, Ahmed SF, Auchus R, Baratz A, Baratz Dalke K, Liao LM, Lin-Su K, Looijenga LH, Mazur T, Meyer-Bahlburg HF, Mouriquand P, Quigley CA, Sandberg DE, Vilain E, Witchel S, and the Global DSD Update Consortium (2016-01-28).
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was irreparably malformed or "too small to stand to urinate or penetrate a vagina," because the surgeons claimed to be able to construct vaginas where none existed. The majority of these genetic males who were reassigned and surgically converted had
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On July 28, 2020, Lurie Children's Hospital became the first children's hospital in the United States to cease medically unnecessary, cosmetic surgery on intersex infants and publicly apologize to past intersex individuals harmed by such surgeries.
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In April 2015, Malta became the first country to recognize a right to bodily integrity and physical autonomy, and outlaw non-consensual modifications to sex characteristics. The Act was widely welcomed by civil society organizations.
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surgery to new levels of success and safety. These specialized surgeons began to repair wider varieties of birth defects at younger ages with better results. Earlier correction reduced the social "differentness" of a child with a
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history of surgical treatment. Participating children reported significant disturbances, especially within family life and physical well-being – these are areas that the medical and surgical treatment was supposed to stabilize.
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In addition to ignoring patients' voices, physicians involved in intersex care had embarrassingly little long-term outcome data to support their claims. In 1997 a patient account was published which could not be ignored.
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By 1990, biological factors were being reported for a wide variety of human behaviors and personality characteristics. The idea that culture accounted for all the differences between men and women seemed as obsolete as
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published a report documenting the negative effects of medically unnecessary surgeries on intersex children in the US, as well as the pressure placed on parents to consent to the operations without full information.
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Genital reconstructive surgery at that time was primarily performed on older children and adults. In the early 1950s, it consisted primarily of the ability to remove an unwanted or nonfunctional gonad, to bring a
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described how a hermaphrodite could inherit "either as male or female, according to that kind of sexe which doth prevaile." Single cases have been described by legal cases sporadically over the centuries.
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Piaggio LA. Congenital Adrenal Hyperplasia: Review from a Surgeon's Perspective in the Beginning of the Twenty-First Century. Front Pediatr. 2014;1:50. Published 2014 Jan 2. doi:10.3389/fped.2013.00050
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published a report on the situation of intersex persons in Denmark and Germany and launched a campaign for intersex human's rights: "First, Do No Harm: ensuring the rights of children born intersex".
622:, Canon and common law referred to a person's sex as male, female or hermaphrodite, with legal rights as male or female depending on the characteristics that appeared most dominant. The foundation of 982:
later reported that Reimer failed to identify as female since the age of 9 to 11, making the transition to living as a male at age 15. The specific case of David Remier and his rejection of female
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A 2016 paper on "Surgery in disorders of sex development (DSD) with a gender issue" repeated many of the same claims, but without reference to human rights norms. A commentary to that article by
978:) who had lost his penis to a surgical accident. This experiment proved not to be as successful as Money claimed. David Reimer grew up as a girl, but never identified as one. Academic sexologist 811:
in the new "Psychohormonal Research Unit" at Hopkins, and his partners, John and Joan Hampson, analyzed these assignments and reassignments in an attempt to learn the timing and sources of
1014:. Nevertheless, in the 1980s several factors began to induce a decline in the frequency of certain types of genital surgery. Pediatric endocrinologists had realized that some boys with 1768:
Details of techniques for feminizing surgery from the first two decades, including an explanation of how the size of the phallus is the most important aspect of assignment decisions.
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The Academy is deeply concerned about the emotional, cognitive, and body image development of intersexuals, and believes that successful early genital surgery minimizes these issues.
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conditions was relatively primitive, based on identifying the type of gonad(s) by palpation or by surgery. Since ability to determine even the type of gonads in infancy was limited,
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In 1779, in England, a seven-year-old intersex child, initially assigned female, underwent the first recorded surgery during modern times, resulting in their reassignment as male.
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medical management. Many felt that a child could not become a happy adult if his penis was too small to insert in a vagina, or if her vagina was too small to receive a penis.
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continued on boys with severe hypospadias and the other conditions outlined above, with continued modifications and refinements intended to reduce unsatisfactory outcomes.
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Markantes G, Deligeoroglou E, Armeni A, Vasileiou V, Damoulari C, Mandrapilia A, Kosmopoulou F, Keramisanou V, Georgakopoulou D, Creatsas G, Georgopoulos N (2015-07-10).
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function was better in men than women. Outcomes suggest infant reassignment to female and surgery does not produce an improved adult satisfaction with sexual function.
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is atypical." The term has been controversial and not widely adopted outside clinical settings: the World Health Organization and many medical journals still refer to
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In the 1980s research in both animals and humans began to provide evidence that sex hormones play an important role in early life in promoting or constraining adult
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Meyer-Bahlburg H, Migeon C, Berkovitz G, Gearhart J, Dolezal C, Wisniewski A (2004). "Attitudes of Adult 46,XY Intersex Persons to Clinical Management Policies".
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A report from Hopkins from the mid-1980s, describing varied approaches for variations of feminizing surgery, including a case of sex reassignment for micropenis.
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won the first successful case brought against a surgeon for non-consensual surgical intervention. The Regional Court of Cologne, Germany, awarded her €100,000.
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Throughout the 1980s pediatric surgery textbooks recommended female assignment and feminizing reconstructive surgery for XY infants with a severely inadequate
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infants with this variation were surviving and could be operated upon. A conflation was then established between life-saving treatment and cosmetic surgeries.
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Wisniewski AB, Migeon CJ (2000). "Long-term perspectives for 46,XY patients affected by complete androgen insensitivity or congenital micropenis".
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continued to be recommended and performed throughout the 1990s on most virilized infant girls with CAH, as well as infants with ambiguity due to
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Lobe TE, Woodall DL, Richards GE, Cavallo A, Meyer WJ (1987). "The complications of surgery for intersex: changing patterns over two decades".
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This was the standard work on intersex conditions until the middle of the 20th century, and helped establish the reputation of Johns Hopkins.
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Oesterling JE, Gearhart JP, Jeffs RD (1987). "A unified approach to early reconstructive surgery of the child with ambiguous genitalia".
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and Special Rapporteur on Torture have all published reports calling for changes to clinical practice and an end to harmful practices.
915:, recognition of the value of sexuality in people's lives, the separation of sexuality from reproduction by increasing availability of 583: 974:
published his influential text on the development of gender identity, and reported successful reassignment at age 22 months of a boy (
3281: 2085:; 31 were raised as boys and treated with extra testosterone. Causes of partial undervirilization with ambiguity included defects of 2794: 1184:
literature tend to focus on surgical techniques with no reports on patient experiences". A 2014 civil society submission to the
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E Coke, The First Part of the Institutes of the Laws of England, Institutes 8.a. (1st Am. Ed. 1812) (16th European ed. 1812).
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Management and understanding of intersex conditions has significantly improved, particularly over the last several decades...
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is the first to record medical procedures associated with intersex gender affirmation surgery in his account of the life of
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sexual behavior and even gender identity. Examples of apparent androgen determination of gender identity in XY people with
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Between 1953 and the 1980s (i.e., all patients who were above 21 in 2000) 183 infants and children had been seen in the
1861:"David Reimer and John Money Gender Reassignment Controversy: The John/Joan Case | The Embryo Project Encyclopedia" 1846: 726:. Most of Young's intersex patients were adults willingly seeking his help with physical problems of genital function. 628: 2917: 1083: 1058: 986:
despite being socialized and medicalized as a girl showed gender identity as inherent to a person. The surgeries and
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to their preferred genitals were being developed in response to requests for such surgery from transgender patients.
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On the management of differences of sex development. Ethical issues relating to "intersexuality".Opinion No. 20/2012
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Gaetano P (15 November 2011). "David Reimer and John Money Gender Reassignment Controversy: The John/Joan Case".
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By 1970, surgeons still considered it easier to "dig a hole" than "build a pole", but had abandoned "barbaric"
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An example of a now-obsolete recommendation to consider reassigning a boy with severe micropenis as a girl.
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Greenberg J (1999). "Defining Male and Female: Intersexuality and the Collision Between Law and Biology".
2325:"Discordant sexual identity in some genetic males with cloacal exstrophy assigned to female sex at birth" 1137:(1) not having surgery at all might be an option; (2) they might have had lower rates of reoperation for 378: 328: 2025:
Migeon CJ, Wisniewski AB, Brown TR, Rock JA, Meyer-Bahlburg HF, Money J, Berkovitz GD (September 2002).
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in the Dominican Republic had been published, along with reports of masculinized behavior in girls with
3536: 2883: 2813: 2712:""DSD is a Perfectly Fine Term": Reasserting Medical Authority through a Shift in Intersex Terminology" 987: 486: 388: 306: 298: 273: 3270:
Discrimination and violence against individuals based on their sexual orientation and gender identity
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argue that the term DSD was designed to "reinstitutionalise" medical authority over intersex bodies.
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Roughly half of the patients had a satisfactory understanding of their condition; half wanted more.
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Hester JD (2004). "Intersex(es) and informed consent: How physicians' rhetoric constrains choice".
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Eliminating forced, coercive and otherwise involuntary sterilization, An interagency statement
2814:"Childhood surgery for ambiguous genitalia: glimpses of practice changes or more of the same?" 3512:"Denmark and Germany: Authorities failing to protect intersex children from invasive surgery" 2994:"Surgery in disorders of sex development (DSD) with a gender issue: If (why), when, and how?" 2505:"Misrepresentation of Evidence Favoring Early Normalizing Surgery for Atypical Sex Anatomies" 1386: 1284: 658: 112: 75: 54: 1257: 2727: 2612: 2098: 1129: 699:
In the United States genital reconstructive surgery was pioneered between 1930 and 1960 by
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of the 1960s. In its application to children with intersex conditions, this thesis that
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Demand for surgery increased dramatically with better understanding of the condition
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Institutions like the Swiss National Advisory Commission on Biomedical Ethics, the
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Warren C (2014). "Gender reassignment surgery in the 18th century: A case study".
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Swiss National Advisory Commission on Biomedical Ethics NEK-CNE (November 2012).
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Holmes M (2011). "The Intersex Enchiridion: Naming and Knowledge in the Clinic".
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The 1970s and 1980s were perhaps the decades when surgery and surgery-supported
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Resolution 1952/2013, Provision version, Children's right to physical integrity
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In North American and European societies, the 1960s saw the beginning of the "
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Thomas DF (2004). "Gender assignment: background and current controversies".
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Intersex Issues in the International Classification of Diseases: a revision
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Historical review of evolution of techniques for feminizing reconstruction.
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Australian Senate, Community Affairs References Committee (October 2013).
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Rink RC, Adams MC (1998). "Feminizing genitoplasty: state of the art".
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Adams F, ed. (1844). "On Extirpation of the Nympha and Cauda Pudendi".
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pediatric endocrine clinic who had an XY karyotype and complete under
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Involuntary or coerced sterilisation of intersex people in Australia
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Genital Abnormalities, Hermaphroditism, and Related Adrenal Diseases
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in October 1996, the academy issued a press statement stating that:
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Jones T, Hart B, Carpenter M, Ansara G, Leonard W, Lucke J (2016).
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Similar controversy occurred in Europe and Latin America. In 1999
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in Baltimore and other major university centers. Understanding of
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United Nations High Commissioner for Human Rights (May 4, 2015),
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Passerini-Glazel G (1999). "Editorial: feminizing genitoplasty".
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over biology became part of the intellectual underpinning of the
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Creighton SM, Michala L, Mushtaq I, Yaron M (January 2, 2014).
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people were performed at least from the seventh century on, in
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Consensus Statement on Intersex Disorders and their Management
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in favor of "nerve sparing" clitoral recession and promised
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A 2016 follow-up to the 2006 Consensus Statement, termed a
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is intertwined with the development of the specialities of
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J, Sibai H, Wisniewski A, Wolffenbuttel KP, Lee P (2016).
2073:. The 26 with complete undervirilization included 20 with 3223: 2625: 2565:"Consensus statement on management of intersex disorders" 2563:
Lee P. A., Houk C. P., Ahmed S. F., Hughes I. A. (2006).
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were determined mainly by the appearance of the external
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textbooks recommended sex reassignment for a male whose
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for isolated micropenis were carried out by the 1990s.
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malformation, or could save the life of an infant with
3384:"We celebrate Maltese protections for intersex people" 2710:
Davis G (3 August 2011). McGann PJ, Hutson DJ (eds.).
2259:'s failed sex reassignment). New York: HarperCollins. 2673: 1467:
Improved techniques will lower the complication rate.
1280:
passed a resolution condemning the practice in 2018.
2689:. Canberra: Community Affairs References Committee. 2252:
As Nature Made Him: The Boy Who Was Raised as a Girl
1845:. Arizona State University School of Life Sciences. 3286:
Office of the UN High Commissioner for Human Rights
1560:
The case of a boy, who had been mistaken for a girl
1344: 1064: 3297: 2174:"Hermaphrodites with Attitude Take to the Streets" 1896: 1783:. Baltimore: Johns Hopkins University Press, 1972. 1002:, financial instability, and a troubled marriage. 1792: 612:, with our increasingly refined understanding of 3608: 2198:"When Max Beck and Morgan Holmes went to Boston" 2121: 1632:Clinical Pediatric and Adolescent Endocrinology. 1251:Office of the High Commissioner for Human Rights 863:Rise of infant surgery and "nurture over nature" 2900:Intersex: Stories and Statistics from Australia 3282:Report of the UN Special Rapporteur on Torture 3208:, Commissioner for Human Rights (April 2015), 3047:"Still ignoring human rights in intersex care" 2322: 761:for treatment led to partial understanding of 3411: 3388:Organisation Intersex International Australia 3211:Human rights and intersex people, Issue Paper 2668:An Interview with Dr. Tiger Howard Devore PhD 1687:Hendrick M (1993). "Is it a Boy or a Girl?". 1630:"Disorders of the testes". In: Kaplan S, ed. 879:were universally admired for bringing infant 577: 2670:, We Who Feel Differently, February 7, 2011. 2401:Creighton S, Minto, Catherine (2001-12-01). 1326:(DoDI) 6130.03, 2018, section 5, 13f and 14m 853:determination of what sex should be assigned 789:or to change the position of the urethra in 741:and others around 1950. For the first time, 3372: 3351: 3040: 2759: 2502: 3462:"US: Harmful Surgery on Intersex Children" 3357: 3318: 3174:: CS1 maint: location missing publisher ( 2186: 1754: 1523:Adams F, ed. (1844). "On Hermaphrodites". 1207:Global Disorders of Sex Development Update 990:on David Remier caused the development of 665:Surgical pioneering and constructed gender 584: 570: 3378: 3275: 3261: 3109: 3091: 3009: 2959: 2832: 2795:"Malta Bans Surgery on Intersex Children" 2703: 2588: 2536: 2428: 2348: 2245: 2042: 1978: 1715: 1499: 1477: 1475: 1417: 1372: 1170:On surgical rationales and outcomes, the 693:and how to remove the enlarged clitoris. 3424: 1686: 1627: 1123: 645:(1805–1861), who pioneered the field of 3245: 3229:Sexual health, human rights and the law 3217: 3182: 2934: 2906:. Cambridge, UK: Open Book Publishers. 2279: 2209: 1838: 1793:Diamond M, Sigmundson HK (March 1997). 867:By the 1960s, the young specialties of 851:(by checking gonads or chromosomes) to 661:implications of medical interventions. 620:Prior to the medicalization of intersex 3609: 3537:"The rights of children born intersex" 3324: 2792: 2765: 2558: 2556: 2192: 1935: 1701: 1573: 1556: 1482:Lascaratos J, Kostakopoulos A (1997). 1472: 1345:Raming I, Macy G, Bernard J C (2004). 1226: 1005: 827:or hormones. This apparent primacy of 681:possibly as early as the 2nd century. 3231:. Geneva: World Health Organization. 2709: 2661: 1877: 1600: 1539: 1522: 1338: 1273:Interact Advocates for Intersex Youth 1155:traits or conditions. Academics like 3291: 2162: 1811:10.1001/archpedi.1997.02170400084015 1786: 1059:Masculinizing reconstructive surgery 849:determination of the baby's real sex 3198: 2553: 1849:from the original on 11 March 2023. 1605:. Baltimore: Williams and Wilkins. 967:(typically less than 1.5 cm). 477:Genital modification and mutilation 13: 2728:10.1108/S1057-6290(2011)0000012012 2377:"The Rights of the Intersex Child" 2093:, partial androgen insensitivity, 1726:10.1023/b:meta.0000025069.46031.0e 1704:Theoretical Medicine and Bioethics 1543:The Seven Books of Paulus Aegineta 1526:The Seven Books of Paulus Aegineta 1163:, and clinical psychologists like 629:Institutes of the Lawes of England 41: 14: 3633: 2466:10.1097/01.ju.0000117761.94734.b7 1393: 1347:A History of Women and Ordination 1084:Intersex Society of North America 1043:feminizing reconstructive surgery 3334:Global Action for Trans Equality 2168: 2037:(3): electronic pages, pp. e32. 1950:10.1111/j.1464-410x.2004.04709.x 1065:Patient advocacy groups speak up 108:Sex characteristics (legal term) 3579: 3554: 3529: 3504: 3479: 3454: 3405: 3134: 3085: 3034: 2984: 2948:Hormone Research in Paediatrics 2890: 2849: 2805: 2786: 2605: 2496: 2445: 2394: 2369: 2323:Reiner WG, Gearhart JP (2004). 2316: 2273: 2239: 2115: 2075:complete androgen insensitivity 2018: 1972: 1929: 1890: 1871: 1853: 1832: 1781:Man & Woman, Boy & Girl 1773: 1748: 1695: 1680: 1642: 1621: 1612: 1594: 1567: 1188:cited data from a large German 1047:androgen insensitivity syndrome 963:-type malformations or extreme 763:androgen insensitivity syndrome 3438:. 1 April 2015. Archived from 3412:Star Observer (2 April 2015). 2217:American Academy of Pediatrics 1550: 1533: 1516: 1434: 1366: 1357: 1301:Intersex medical interventions 1089:American Academy of Pediatrics 1036:congenital adrenal hyperplasia 998:, owing to suffering years of 731:congenital adrenal hyperplasia 673:"reconstructive" surgeries on 643:Isidore Geoffroy Saint-Hilaire 20:Intersex medical interventions 1: 2716:Advances in Medical Sociology 2298:10.1016/S0022-5347(01)68054-6 2065:, partial undervirilization ( 1911:10.1016/s0022-5347(05)68987-2 1663:10.1016/S0022-5347(17)43508-7 1455:10.1016/S0022-3468(87)80119-7 3358:OII Europe (April 1, 2015). 3063:10.1016/j.jpurol.2016.05.017 3051:Journal of Pediatric Urology 3011:10.1016/j.jpurol.2016.04.001 2998:Journal of Pediatric Urology 2834:10.1080/19419899.2013.831214 2503:Baratz AB, Feder EK (2015). 2280:Diamond M (September 1999). 2179:Hermaphrodites with Attitude 2097:hypoplasia, timing defects, 1878:Ishak N (January 12, 2021). 1757:"Intersex". In: Ravitch MM, 1443:Journal of Pediatric Surgery 1278:California State Legislature 1233:Timeline of intersex history 1190:Netzwerk DSD/Intersexualität 1133:to inform respondents that: 1032:5-alpha-reductase deficiency 334:International Intersex Forum 134:Disorders of sex development 7: 3098:Reproductive Health Matters 2621:"Sex, health, and athletes" 2509:Archives of Sexual Behavior 1842:Embryo Project Encyclopedia 1755:Walsh PC, Scott WW (1979). 1546:. Vol. 2. p. 381. 1529:. Vol. 2. p. 381. 1294: 685:(c. 625 – c. 690), quoting 598:history of intersex surgery 329:Intersex Day of Remembrance 217:Civil society organizations 10: 3638: 2793:Dreger A (April 3, 2015). 1635:. Philadelphia: Saunders. 1230: 843:changed the management of 757:, and the availability of 274:Sex verification in sports 17: 3256:World Health Organization 3225:World Health Organization 3111:10.1016/j.rhm.2016.06.003 2521:10.1007/s10508-015-0529-x 2421:10.1136/bmj.323.7324.1264 1247:World Health Organization 1186:World Health Organization 823:more closely than it did 797:opening, and to remove a 3092:Carpenter M (May 2016). 2821:Psychology and Sexuality 2255:(the popular account of 1799:Arch Pediatr Adolesc Med 1588:10.1177/1363460714531270 1488:Urologia Internationalis 1331: 1321:Sex reassignment surgery 942:when the girls grew up. 66:Compulsory sterilization 3150:. Berne. Archived from 2408:British Medical Journal 2107:developmentally delayed 1944:(Supplement 3): 47–50. 1419:10.14310/horm.2002.1608 944:Pediatric endocrinology 610:pediatric endocrinology 3591:www.luriechildrens.org 2882:: CS1 maint: others ( 2780:10.3366/soma.2011.0026 2581:10.1542/peds.2006-0738 2454:The Journal of Urology 2044:10.1542/peds.110.3.e32 1884:All That's Interesting 1779:Money J, Ehrhardt AA. 1689:Johns Hopkins Magazine 1216: 1199: 1181: 1144: 1106: 708:Johns Hopkins Hospital 706:and other surgeons at 614:sexual differentiation 519:Non-binary recognition 324:Intersex Awareness Day 186:Sexual differentiation 46: 3617:Intersex and medicine 3301:(December 17, 2015). 1993:10.1007/s003450050055 1285:Amnesty International 1231:Further information: 1211: 1194: 1176: 1135: 1124:Outcomes and evidence 1093: 809:clinical psychologist 785:, to repair a milder 222:Fictional characters‎ 154:Medical interventions 113:Yogyakarta Principles 98:Medical interventions 45: 18:Further information: 2613:Rebecca Jordan-Young 2341:10.1056/nejmoa022236 2136:10.1055/s-2002-35376 2099:true hermaphroditism 1130:Heino Meyer-Bahlburg 877:children's hospitals 509:Anti-gender movement 279:at the Olympic Games 3622:Intersex in history 2089:synthesis, partial 2067:ambiguous genitalia 1657:(4 Pt 2): 1079–82. 1311:Intersex in history 1306:Intersex healthcare 1227:Recent developments 1006:Complications arise 988:hormone replacement 845:ambiguous genitalia 841:social construction 839:was a many-faceted 639:Callon of Epidaurus 205:Society and culture 24:Intersex in history 3466:Human Rights Watch 3436:The New York Times 3299:Zwischengeschlecht 2292:(3 Pt 2): 1021–8. 2286:Journal of Urology 2103:feminizing surgery 2091:gonadal dysgenesis 2083:feminizing surgery 1375:Arizona Law Review 1269:Human Rights Watch 1258:Christiane Völling 1051:gonadal dysgenesis 1018:had deficiency of 921:sexual orientation 704:Hugh Hampton Young 47: 3382:(April 2, 2015). 3328:(April 8, 2015). 3238:978-92-4-156498-4 3206:Council of Europe 3193:Council of Europe 2961:10.1159/000442975 2913:978-1-78374-208-0 2799:The Stranger SLOG 2737:978-0-85724-575-5 2696:978-1-74229-917-4 2639:10.1136/bmj.g2926 2615:, Peter Sonksen, 2266:978-0-06-019211-2 1938:BJU International 1763:Pediatric surgery 1628:Penny R. (1982). 1601:Young HH (1937). 1557:Thomas B (1787). 1501:10.1159/000282990 1243:Council of Europe 1239:Australian Senate 1055:cloacal exstrophy 1000:severe depression 961:cloacal exstrophy 909:sexual revolution 873:pediatric urology 869:pediatric surgery 833:feminist movement 817:sex of assignment 739:Frederick Bartter 716:sex of assignment 652:Since the 1920s, 606:pediatric urology 602:pediatric surgery 594: 593: 472:Children's rights 347:Rights by country 237:Intersex and LGBT 139:Genetic diagnosis 93:Malta declaration 88:Legal recognition 3629: 3601: 3600: 3598: 3597: 3583: 3577: 3576: 3574: 3573: 3558: 3552: 3551: 3549: 3548: 3533: 3527: 3526: 3524: 3523: 3508: 3502: 3501: 3499: 3498: 3493:. 28 August 2018 3483: 3477: 3476: 3474: 3473: 3458: 3452: 3451: 3449: 3447: 3428: 3422: 3421: 3409: 3403: 3402: 3400: 3399: 3390:. Archived from 3376: 3370: 3369: 3367: 3366: 3355: 3349: 3348: 3346: 3345: 3336:. Archived from 3322: 3316: 3315: 3313: 3312: 3307: 3295: 3289: 3288:, February 2013. 3279: 3273: 3272: 3265: 3259: 3249: 3243: 3242: 3221: 3215: 3214: 3202: 3196: 3195:, 1 October 2013 3186: 3180: 3179: 3173: 3165: 3163: 3162: 3156: 3149: 3138: 3132: 3131: 3113: 3089: 3083: 3082: 3038: 3032: 3031: 3013: 2988: 2982: 2981: 2963: 2938: 2932: 2931: 2929: 2928: 2922: 2916:. Archived from 2905: 2894: 2888: 2887: 2881: 2873: 2870:Morgan Carpenter 2863: 2853: 2847: 2846: 2836: 2818: 2809: 2803: 2802: 2790: 2784: 2783: 2763: 2757: 2756: 2754: 2752: 2707: 2701: 2700: 2680: 2671: 2665: 2659: 2658: 2617:Katrina Karkazis 2609: 2603: 2602: 2592: 2560: 2551: 2550: 2540: 2515:(7): 1761–1763. 2500: 2494: 2493: 2460:(4): 1615–1619. 2449: 2443: 2442: 2432: 2415:(7324): 1264–5. 2398: 2392: 2391: 2389: 2388: 2373: 2367: 2366: 2352: 2320: 2314: 2313: 2308:. Archived from 2277: 2271: 2270: 2243: 2237: 2236: 2234: 2233: 2219:(October 1996). 2213: 2207: 2206: 2196:(October 2015), 2190: 2184: 2183: 2166: 2160: 2159: 2124:Semin Reprod Med 2119: 2113: 2112: 2046: 2022: 2016: 2015: 1976: 1970: 1969: 1933: 1927: 1926: 1894: 1888: 1887: 1875: 1869: 1868: 1857: 1851: 1850: 1836: 1830: 1829: 1827: 1825: 1790: 1784: 1777: 1771: 1770: 1752: 1746: 1745: 1719: 1699: 1693: 1692: 1684: 1678: 1677: 1646: 1640: 1639: 1625: 1619: 1616: 1610: 1609: 1598: 1592: 1591: 1571: 1565: 1564: 1554: 1548: 1547: 1537: 1531: 1530: 1520: 1514: 1513: 1503: 1479: 1470: 1469: 1438: 1432: 1431: 1421: 1397: 1391: 1390: 1370: 1364: 1361: 1355: 1354: 1342: 1128:A 2004 paper by 992:gender dysphoria 948:child psychology 928:sex reassignment 671:Byzantine Empire 635:Diodorus Siculus 586: 579: 572: 30: 29: 3637: 3636: 3632: 3631: 3630: 3628: 3627: 3626: 3607: 3606: 3605: 3604: 3595: 3593: 3585: 3584: 3580: 3571: 3569: 3560: 3559: 3555: 3546: 3544: 3541:www.amnesty.org 3535: 3534: 3530: 3521: 3519: 3516:www.amnesty.org 3510: 3509: 3505: 3496: 3494: 3485: 3484: 3480: 3471: 3469: 3460: 3459: 3455: 3445: 3443: 3442:on 4 April 2015 3430: 3429: 3425: 3410: 3406: 3397: 3395: 3377: 3373: 3364: 3362: 3356: 3352: 3343: 3341: 3340:on July 4, 2015 3323: 3319: 3310: 3308: 3305: 3296: 3292: 3280: 3276: 3266: 3262: 3250: 3246: 3239: 3222: 3218: 3203: 3199: 3187: 3183: 3167: 3166: 3160: 3158: 3154: 3147: 3139: 3135: 3090: 3086: 3039: 3035: 2989: 2985: 2939: 2935: 2926: 2924: 2920: 2914: 2903: 2895: 2891: 2875: 2874: 2861: 2855: 2854: 2850: 2816: 2810: 2806: 2791: 2787: 2764: 2760: 2750: 2748: 2738: 2708: 2704: 2697: 2681: 2674: 2666: 2662: 2610: 2606: 2575:(2): e488–500. 2561: 2554: 2501: 2497: 2450: 2446: 2399: 2395: 2386: 2384: 2375: 2374: 2370: 2321: 2317: 2278: 2274: 2267: 2244: 2240: 2231: 2229: 2214: 2210: 2191: 2187: 2167: 2163: 2120: 2116: 2023: 2019: 1977: 1973: 1934: 1930: 1895: 1891: 1876: 1872: 1859: 1858: 1854: 1837: 1833: 1823: 1821: 1791: 1787: 1778: 1774: 1753: 1749: 1717:10.1.1.693.6468 1700: 1696: 1685: 1681: 1647: 1643: 1626: 1622: 1617: 1613: 1599: 1595: 1572: 1568: 1555: 1551: 1538: 1534: 1521: 1517: 1480: 1473: 1439: 1435: 1398: 1394: 1371: 1367: 1362: 1358: 1351:Scarecrow Press 1343: 1339: 1334: 1297: 1283:The same year, 1235: 1229: 1157:Georgiann Davis 1126: 1067: 1008: 984:gender identity 865: 829:social learning 813:gender identity 771:sex assignments 755:sex chromosomes 667: 590: 561: 560: 556:Sex differences 462: 454: 453: 349: 339: 338: 302: 291: 290: 206: 198: 197: 129: 118: 117: 61: 26: 12: 11: 5: 3635: 3625: 3624: 3619: 3603: 3602: 3578: 3553: 3528: 3503: 3478: 3453: 3423: 3404: 3371: 3350: 3317: 3290: 3274: 3260: 3244: 3237: 3216: 3197: 3181: 3133: 3084: 3057:(6): 436–437. 3033: 3004:(3): 139–149. 2983: 2954:(3): 158–180. 2933: 2912: 2889: 2848: 2804: 2785: 2758: 2736: 2702: 2695: 2672: 2660: 2604: 2552: 2495: 2444: 2393: 2368: 2315: 2312:on 2007-06-22. 2272: 2265: 2238: 2208: 2185: 2161: 2130:(3): 297–304. 2114: 2079:Swyer syndrome 2017: 1987:(3): 212–218. 1971: 1928: 1889: 1870: 1865:embryo.asu.edu 1852: 1831: 1805:(3): 298–304. 1785: 1772: 1747: 1694: 1679: 1641: 1620: 1611: 1593: 1582:(7): 872–884. 1566: 1549: 1532: 1515: 1494:(4): 232–235. 1471: 1433: 1412:(3): 459–461. 1392: 1365: 1356: 1353:. p. 113. 1336: 1335: 1333: 1330: 1329: 1328: 1323: 1318: 1316:Sex assignment 1313: 1308: 1303: 1296: 1293: 1228: 1225: 1149:anatomical sex 1125: 1122: 1105: 1104: 1101: 1097: 1066: 1063: 1020:growth hormone 1007: 1004: 980:Milton Diamond 936:clitorectomies 864: 861: 821:sex of rearing 807:, a pediatric 735:Lawson Wilkins 683:Paul of Aegina 666: 663: 592: 591: 589: 588: 581: 574: 566: 563: 562: 559: 558: 553: 548: 543: 541:Medical ethics 538: 537: 536: 531: 526: 521: 516: 511: 506: 496: 491: 490: 489: 479: 474: 469: 463: 460: 459: 456: 455: 452: 451: 446: 444:United Kingdom 441: 436: 431: 426: 421: 416: 411: 406: 401: 396: 391: 386: 381: 376: 371: 366: 361: 356: 350: 345: 344: 341: 340: 337: 336: 331: 326: 321: 320: 319: 314: 303: 297: 296: 293: 292: 289: 288: 283: 282: 281: 271: 266: 265: 264: 254: 249: 244: 239: 234: 229: 224: 219: 214: 207: 204: 203: 200: 199: 196: 195: 188: 183: 178: 173: 168: 163: 162: 161: 151: 146: 141: 136: 130: 124: 123: 120: 119: 116: 115: 110: 105: 103:Sex assignment 100: 95: 90: 85: 84: 83: 73: 71:Discrimination 68: 62: 53: 52: 49: 48: 38: 37: 9: 6: 4: 3: 2: 3634: 3623: 3620: 3618: 3615: 3614: 3612: 3592: 3588: 3582: 3567: 3563: 3557: 3542: 3538: 3532: 3517: 3513: 3507: 3492: 3488: 3482: 3467: 3463: 3457: 3441: 3437: 3433: 3427: 3419: 3418:Star Observer 3415: 3408: 3394:on 2015-07-04 3393: 3389: 3385: 3381: 3375: 3361: 3354: 3339: 3335: 3331: 3327: 3321: 3304: 3300: 3294: 3287: 3283: 3278: 3271: 3264: 3257: 3253: 3248: 3240: 3234: 3230: 3226: 3220: 3213: 3212: 3207: 3201: 3194: 3190: 3185: 3177: 3171: 3157:on 2015-04-23 3153: 3146: 3145: 3137: 3129: 3125: 3121: 3117: 3112: 3107: 3104:(47): 74–84. 3103: 3099: 3095: 3088: 3080: 3076: 3072: 3068: 3064: 3060: 3056: 3052: 3048: 3044: 3037: 3029: 3025: 3021: 3017: 3012: 3007: 3003: 2999: 2995: 2987: 2979: 2975: 2971: 2967: 2962: 2957: 2953: 2949: 2945: 2937: 2923:on 2016-09-14 2919: 2915: 2909: 2902: 2901: 2893: 2885: 2879: 2872:(eds.). 2014. 2871: 2867: 2860: 2859: 2852: 2844: 2840: 2835: 2830: 2826: 2822: 2815: 2808: 2800: 2796: 2789: 2781: 2777: 2774:(2): 87–114. 2773: 2769: 2762: 2747: 2743: 2739: 2733: 2729: 2725: 2721: 2717: 2713: 2706: 2698: 2692: 2688: 2687: 2679: 2677: 2669: 2664: 2656: 2652: 2648: 2644: 2640: 2636: 2632: 2628: 2627: 2622: 2618: 2614: 2608: 2600: 2596: 2591: 2586: 2582: 2578: 2574: 2570: 2566: 2559: 2557: 2548: 2544: 2539: 2534: 2530: 2526: 2522: 2518: 2514: 2510: 2506: 2499: 2491: 2487: 2483: 2479: 2475: 2471: 2467: 2463: 2459: 2455: 2448: 2440: 2436: 2431: 2426: 2422: 2418: 2414: 2410: 2409: 2404: 2397: 2382: 2378: 2372: 2365: 2360: 2356: 2351: 2346: 2342: 2338: 2335:(4): 333–41. 2334: 2330: 2326: 2319: 2311: 2307: 2303: 2299: 2295: 2291: 2287: 2283: 2276: 2268: 2262: 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Index

Intersex medical interventions
Intersex in history
Intersex
Intersex flag
Human rights
legal issues
Compulsory sterilization
Discrimination
Human rights
reports
Legal recognition
Malta declaration
Medical interventions
Sex assignment
Sex characteristics (legal term)
Yogyakarta Principles
Medicine
Disorders of sex development
Genetic diagnosis
Definitions
Healthcare
Medical interventions
history
Orchidometer
Phall-O-Meter
Prader scale
Quigley scale
Sexual differentiation
more...
Endosex

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