246:
223:
145:
120:
504:
252:
151:
497:
1326:(Hp) concentrations are low or depleted as a result of severe or prolonged hemolysis. Both haptoglobin and hemopexin are acute-phase proteins, the synthesis of which are induced during infection and after inflammatory states to minimize tissue injury and facilitate tissue repair. Hp and hemopexin prevent heme toxicity by binding themselves to heme prior to
1334:'s arrivals and ensuing clearances, which may explain their effects on outcome in several diseases, and underlies the rationale for exogenous haptoglobin and hemopexin as therapeutic proteins in hemolytic or hemorrhagic conditions. Hemopexin is the major vehicle for the transportation of heme in the plasma.
1183:
In 1986, the expression of the human HPX gene in different human tissues and cell lines was carried out by using a specific cDNA probe. From the results obtained it was concluded that this gene was expressed in the liver and it was below the level of detection in other tissues or cell lines examined.
1149:
and the 10 repeating units in the protein. The introns were not placed randomly; they fell in the center of the region of amino acid sequence homology in strikingly similar locations in 6 of the 10 units and in a symmetric position in each half of the coding sequence. From these observations, Altruda
1240:
The predominant source of circulating hemopexin is the liver with a plasma concentration of 1–2 mg/ml. Serum hemopexin level reflects how much heme is present in the blood. Therefore, a low hemopexin level indicates that there has been significant degradation of heme containing compounds. A low
2126:
1090:. The free heme will then be oxidized into free met-heme and sooner or later the hemopexin will come to bind free met-heme together, forming a complex of met-heme and hemopexin, continuing their journey in the circulation until reaching a receptor, such as
1166:
analysis of human/hamster hybrids containing different combinations of human chromosomes, assigned the HPX gene to human chromosome 11. Law et al. (1988) assigned the HPX gene to 11p15.5-p15.4, the same location as that of the
259:
158:
1142:
positions. Computer-assisted analysis of the internal homology in amino acid sequence suggested duplication of an ancestral gene thus indicating that hemopexin consists of two similar halves.
2638:"Interaction of hemopexin with Sn-protoporphyrin IX, an inhibitor of heme oxygenase. Role for hemopexin in hepatic uptake of Sn-protoporphyrin IX and induction of mRNA for heme oxygenase"
1950:
Krikken JA, Lely AT, Bakker SJ, Borghuis T, Faas MM, van Goor H, Navis G, Bakker WW (March 2013). "Hemopexin activity is associated with angiotensin II responsiveness in humans".
1901:"Hemoglobin and its scavenger protein haptoglobin associate with apoA-1-containing particles and influence the inflammatory properties and function of high density lipoprotein"
1097:
Hemopexin's arrival and subsequent binding to the free heme not only prevent heme's pro-oxidant and pro-inflammatory effects but also promotes free heme's detoxification.
2855:
Morris CM, Candy JM, Edwardson JA, Bloxham CA, Smith A (January 1993). "Evidence for the localization of haemopexin immunoreactivity in neurones in the human brain".
4028:
1145:
Altruda et al. (1988) demonstrated that the HPX gene spans approximately 12 kb and is interrupted by 9 exons. The demonstration shows direct correspondence between
3030:
Nakajima S, Moriyama T, Hayashi H, Sakata I, Nakae Y, Takemura T (February 2000). "Hemopexin as a carrier protein of tumor-localizing Ga-metalloporphyrin-ATN-2".
1138:, and the protein has five N-linked glycan modifications. The 18 tryptophan residues are arranged in four clusters, and 12 of the tryptophans are conserved in
2607:
Law ML, Cai GY, Hartz JA, Jones C, Kao FT (July 1988). "The hemopexin gene maps to the same location as the beta-globin gene cluster on human chromosome 11".
2972:
Miller YI, Smith A, Morgan WT, Shaklai N (October 1996). "Role of hemopexin in protection of low-density lipoprotein against hemoglobin-induced oxidation".
1184:
By S1 mapping, the transcription initiation site in hepatic cells was located 28 base pairs upstream from the AUG initiation codon of the hemopexin gene.
767:
4160:
748:
1123:
Takahashi et al. (1985) determined that human plasma hemopexin consists of a single polypeptide chain of 439 amino acids residues with six intrachain
81:
4194:
3059:
Shipulina N, Smith A, Morgan WT (April 2000). "Heme binding by hemopexin: evidence for multiple modes of binding and functional implications".
2412:
Liu HM, Atack JR, Rapoport SI (1989). "Immunohistochemical localization of intracellular plasma proteins in the human central nervous system".
1087:
2179:"Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage"
1437:
3001:
Grinberg LN, O'Brien PJ, Hrkal Z (July 1999). "The effects of heme-binding proteins on the peroxidative and catalatic activities of hemin".
1419:
1224:(Hp) and Hx associate with high density lipoprotein (HDL) and influence the inflammatory properties of HDL. Hemopexin can downregulate the
4347:
3692:
2935:
Hunt RC, Hunt DM, Gaur N, Smith A (July 1996). "Hemopexin in the human retina: protection of the retina against heme-mediated toxicity".
974:
2948:
2484:
Altruda F, Poli V, Restagno G, Silengo L (1988). "Structure of the human hemopexin gene and evidence for intron-mediated evolution".
1469:
Altruda F, Poli V, Restagno G, Silengo L (1988). "Structure of the human hemopexin gene and evidence for intron-mediated evolution".
1261:
967:
3135:
1455:
1150:
et al. (1988) concluded that the gene evolved through intron-mediated duplications of a primordial sequence to a 5-exon cluster.
4337:
2054:
1267:
HPX is produced in the brain. Deletion of the HPX gene can aggravate brain injury followed by stroma-free hemoglobin-induced
1402:
1659:
3512:
1780:
1706:
1381:
1204:
and thus protects the body from the oxidative damage that free heme can cause. In addition, hemopexin releases its bound
4187:
2822:"Regulation of heme oxygenase and metallothionein gene expression by the heme analogs, cobalt-, and tin-protoporphyrin"
1683:
3552:
245:
3402:
3685:
2287:"Haptoglobin, hemopexin, and related defense pathways-basic science, clinical perspectives, and drug development"
1406:
1385:
222:
2531:"The primary structure of human hemopexin deduced from cDNA sequence: evidence for internal, repeating homology"
1522:"The primary structure of human hemopexin deduced from cDNA sequence: evidence for internal, repeating homology"
1075:, as opposed to the hemoglobin situated in and circulating with the red blood cell.) will soon be oxidized into
4139:
2125:
Garland P, Durnford AJ, Okemefuna AI, Dunbar J, Nicoll JA, Galea J, Boche D, Bulters DO, Galea I (March 2016).
812:
16:
This article is about the hemopexin protein. For the family of proteins containing hemopexin-like repeats, see
4180:
2726:"Structure of human hemopexin: O-glycosyl and N-glycosyl sites and unusual clustering of tryptophan residues"
1315:
144:
119:
2127:"Heme-Hemopexin Scavenging Is Active in the Brain and Associates With Outcome After Subarachnoid Hemorrhage"
793:
3870:
3113:
1220:
repression which leads to the transcriptional activation of antioxidant heme oxygenase-1 gene. Hemoglobin,
61:
2383:
Morgan WT, Muller-Eberhard U, Lamola AA (January 1978). "Interaction of rabbit hemopexin with bilirubin".
4285:
3649:
3128:
1348:
1311:
2342:"Hemopexin domains as multifunctional liganding modules in matrix metalloproteinases and other proteins"
1112:
3678:
3639:
2451:"Importance of ligand-induced conformational changes in hemopexin for receptor-mediated heme transport"
1319:
1998:"Plasma concentrations of hemopexin, haptoglobin and heme in patients with various hemolytic diseases"
258:
157:
4219:
4134:
3602:
3562:
1268:
1200:. Its main function is scavenging the heme released or lost by the turnover of heme proteins such as
251:
150:
48:
4240:
3745:
3542:
3517:
3107:
1796:
Poli V, Altruda F, Silengo L (1986). "Differential transcriptional pattern of the hemopexin gene".
69:
2075:"Role of hemoglobin/heme scavenger protein hemopexin in atherosclerosis and inflammatory diseases"
1899:
Watanabe J, Grijalva V, Hama S, Barbour K, Berger FG, Navab M, Fogelman AM, Reddy ST (July 2009).
4342:
3805:
3755:
3741:
1276:
1264:. The circulating level of hemopexin is associated with prognosis in patients with septic shock.
1242:
950:
929:
903:
882:
3577:
3121:
1249:
2046:
4352:
4250:
3831:
1172:
133:
2038:
4088:
3904:
2737:
2684:
2493:
2241:
1735:
1478:
2228:
Liu J, Lane S, Lall R, Russo M, Farrell L, Debreli Coskun M, et al. (December 2022).
1283:
1060:
of proteins. Hemopexin is the plasma protein with the highest binding affinity for heme.
8:
4311:
4245:
4203:
4083:
4023:
3769:
3759:
3749:
3582:
3507:
3394:
3371:
3335:
3307:
1303:
1272:
89:
2741:
2688:
2497:
2245:
2230:"Circulating hemopexin modulates anthracycline cardiac toxicity in patients and in mice"
1739:
1482:
4255:
4109:
4001:
3532:
3084:
2960:
2923:
2880:
2808:
2517:
2437:
2371:
2313:
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2229:
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2178:
2159:
2099:
2074:
1975:
1927:
1900:
1502:
1139:
93:
3043:
3014:
2838:
2821:
2760:
2725:
2707:
2672:
2654:
2637:
2590:
2573:
2555:
2530:
2467:
2450:
1864:
Tolosano E, Altruda F (April 2002). "Hemopexin: structure, function, and regulation".
1823:
Hvidberg V, Maniecki MB, Jacobsen C, Højrup P, Møller HJ, Moestrup SK (October 2005).
1758:
1723:
1619:
Tolosano E, Altruda F (April 2002). "Hemopexin: structure, function, and regulation".
1587:
1570:
1546:
1521:
682:
677:
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4118:
4018:
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3436:
3103:
3076:
3047:
3018:
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2952:
2915:
2910:
2893:
2872:
2868:
2843:
2800:
2795:
2778:
2765:
2712:
2659:
2624:
2620:
2595:
2560:
2509:
2472:
2429:
2400:
2396:
2363:
2318:
2267:
2210:
2151:
2104:
2050:
2039:
2019:
1967:
1932:
1881:
1846:
1805:
1763:
1636:
1592:
1551:
1494:
1257:
633:
positive regulation of humoral immune response mediated by circulating immunoglobulin
41:
3088:
2964:
2927:
2884:
2812:
2673:"Complete amino acid sequence of human hemopexin, the heme-binding protein of serum"
2521:
2441:
2375:
2163:
1979:
1724:"Complete amino acid sequence of human hemopexin, the heme-binding protein of serum"
1506:
1216:. Hemopexin -dependent uptake of extracellular heme can lead to the deactivation of
3701:
3522:
3339:
3292:
3068:
3039:
3010:
2981:
2944:
2905:
2864:
2833:
2790:
2755:
2745:
2702:
2692:
2649:
2616:
2585:
2550:
2542:
2501:
2462:
2421:
2392:
2353:
2308:
2298:
2257:
2249:
2200:
2190:
2141:
2094:
2086:
2009:
1959:
1922:
1912:
1873:
1836:
1753:
1743:
1628:
1582:
1541:
1533:
1486:
1124:
1057:
338:
269:
213:
168:
73:
17:
4265:
4224:
3860:
3781:
3479:
3451:
3367:
2146:
2090:
1963:
1824:
1135:
313:
97:
2014:
1997:
1442:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1424:
National Center for
Biotechnology Information, U.S. National Library of Medicine
3976:
3933:
3850:
3721:
3629:
3148:
2730:
Proceedings of the
National Academy of Sciences of the United States of America
2677:
Proceedings of the
National Academy of Sciences of the United States of America
1877:
1841:
1728:
Proceedings of the
National Academy of Sciences of the United States of America
1632:
1287:
1128:
1076:
414:
3072:
2195:
4331:
4260:
4093:
4075:
4013:
3971:
3967:
3799:
3634:
3622:
3302:
2546:
2303:
1537:
1307:
1291:
1163:
1132:
532:
3143:
1917:
474:
352:
3765:
3709:
3547:
3459:
3326:
3156:
3152:
3080:
3051:
3022:
2750:
2367:
2322:
2271:
2253:
2214:
2155:
2108:
1971:
1936:
1885:
1850:
1640:
1253:
1046:
331:
110:
2993:
2956:
2919:
2876:
2847:
2804:
2769:
2716:
2663:
2628:
2599:
2564:
2529:
Altruda F, Poli V, Restagno G, Argos P, Cortese R, Silengo L (June 1985).
2513:
2476:
2433:
2177:
Ma B, Day JP, Phillips H, Slootsky B, Tolosano E, Doré S (February 2016).
2023:
1996:
Muller-Eberhard U, Javid J, Liem HH, Hanstein A, Hanna M (November 1968).
1809:
1767:
1596:
1555:
1520:
Altruda F, Poli V, Restagno G, Argos P, Cortese R, Silengo L (June 1985).
1498:
1094:, on hepatocytes or macrophages within the spleen, liver and bone marrow.
1014:
1009:
503:
4316:
4295:
4280:
4124:
4114:
4006:
3957:
3894:
3875:
3835:
3824:
3792:
3659:
3654:
3644:
3617:
3587:
3572:
3441:
3297:
3287:
3164:
2697:
2404:
1748:
1343:
1323:
1225:
1221:
1178:
1168:
1101:
857:
838:
496:
2949:
10.1002/(SICI)1097-4652(199607)168:1<71::AID-JCP9>3.0.CO;2-5
2358:
2341:
1676:
4172:
4055:
3487:
2636:
Morgan WT, Alam J, Deaciuc V, Muster P, Tatum FM, Smith A (June 1988).
2505:
2425:
1490:
1358:
1331:
1201:
1108:
230:
127:
77:
2985:
4060:
4047:
3919:
3597:
3592:
3557:
3469:
712:
297:
284:
196:
183:
85:
3670:
1825:"Identification of the receptor scavenging hemopexin-heme complexes"
1654:
1652:
1650:
4270:
3941:
3909:
3712:
3416:
3411:
3406:
3384:
3379:
3357:
3352:
3312:
1614:
1612:
1610:
1608:
1606:
1327:
998:
628:
positive regulation of interferon-gamma-mediated signaling pathway
4211:
4038:
3981:
3914:
3464:
3347:
3144:
2891:
2779:"Amino acid sequence of the N-terminal region of human hemopexin"
1647:
1322:, a decline in hemopexin concentration occurs in situations when
1197:
824:
779:
697:
693:
2285:
Schaer DJ, Vinchi F, Ingoglia G, Tolosano E, Buehler PW (2014).
1995:
1784:
1710:
1603:
65:
4275:
4065:
3731:
3537:
3256:
3216:
2449:
Smith A, Tatum FM, Muster P, Burch MK, Morgan WT (April 1988).
1245:
1205:
982:
734:
673:
positive regulation of tyrosine phosphorylation of STAT protein
512:
2892:
Hrkal Z, Kuzelová K, Muller-Eberhard U, Stern R (March 1996).
2339:
2124:
1822:
1302:
In past there have been reports showing that in patients with
4129:
3431:
3426:
3271:
3266:
3261:
3251:
3246:
3241:
3221:
3206:
3201:
3186:
3173:
3029:
1571:"A helping hand for collagenases: the haemopexin-like domain"
1217:
1146:
2284:
3612:
3527:
3421:
3236:
3231:
3226:
3211:
3196:
3191:
3181:
2854:
2777:
Frantíková V, Borvák J, Kluh I, Morávek L (December 1984).
2776:
2571:
2382:
1898:
1353:
1282:
Circulating hemopexin can modulate in patients and in mice
1213:
1209:
1193:
1159:
1091:
1083:
1053:
2483:
1468:
2574:"Isolation of the hemopexin receptor from human placenta"
1949:
3000:
2971:
2894:"Hyaluronan-binding properties of human serum hemopexin"
2723:
2670:
2528:
2340:
Piccard H, Van den Steen PE, Opdenakker G (April 2007).
1721:
1519:
1241:
hemopexin level is one of the diagnostic features of an
321:
2635:
2572:
Taketani S, Kohno H, Naitoh Y, Tokunaga R (June 1987).
2385:
Biochimica et
Biophysica Acta (BBA) - Protein Structure
1131:
threonine residue is modified by a mucin-type O-linked
2819:
2045:(5th ed.). Oxford: Blackwell Publishing. p.
1179:
Differential transcriptional pattern of hemopexin gene
2820:
Smith A, Alam J, Escriba PV, Morgan WT (April 1993).
2448:
2176:
1127:
and has a molecular mass of approximately 63 kD. The
1118:
486:
3058:
2671:
Takahashi N, Takahashi Y, Putnam FW (January 1985).
1722:
Takahashi N, Takahashi Y, Putnam FW (January 1985).
2036:
643:
positive regulation of response to interferon-gamma
2724:Takahashi N, Takahashi Y, Putnam FW (April 1984).
1795:
1398:
1396:
1394:
1377:
1375:
1373:
2934:
268:
167:
4329:
2606:
2411:
2227:
623:positive regulation of immunoglobulin production
1863:
1618:
1391:
1370:
1403:GRCm38: Ensembl release 89: ENSMUSG00000030895
4188:
3686:
3129:
2278:
2170:
1857:
1153:
1113:Haptoglobin § Differentiation with hemopexin
1382:GRCh38: Ensembl release 89: ENSG00000110169
4195:
4181:
3693:
3679:
3136:
3122:
2072:
1562:
1513:
1462:
1297:
1208:for internalisation upon interacting with
4161:disorders of globin and globulin proteins
3106:at the U.S. National Library of Medicine
2909:
2837:
2794:
2759:
2749:
2706:
2696:
2653:
2589:
2554:
2466:
2357:
2312:
2302:
2261:
2204:
2194:
2145:
2098:
2013:
1926:
1916:
1840:
1757:
1747:
1586:
1545:
1262:experimental autoimmune encephalomyelitis
441:fetal liver hematopoietic progenitor cell
4202:
1235:
602:collagen-containing extracellular matrix
3442:Structural maintenance of chromosomes 3
1196:with the highest affinity of any known
618:regulation of protein metabolic process
546:heme transmembrane transporter activity
4330:
2037:Hoffbrand A, Moss P, Pettit J (2006).
1275:is associated with poor outcome after
1079:which then further disassociates into
4176:
3700:
3674:
3117:
2120:
2118:
2068:
2066:
1991:
1989:
1448:
273:
234:
229:
172:
131:
126:
1568:
3003:Free Radical Biology & Medicine
2826:The Journal of Biological Chemistry
2642:The Journal of Biological Chemistry
2578:The Journal of Biological Chemistry
2455:The Journal of Biological Chemistry
2073:Mehta NU, Reddy ST (October 2015).
1905:The Journal of Biological Chemistry
1798:The Italian Journal of Biochemistry
1781:Online Mendelian Inheritance in Man
1707:Online Mendelian Inheritance in Man
1248:. Hemopexin has been implicated in
13:
4348:Single-pass transmembrane proteins
2332:
2115:
2063:
1986:
1119:Cloning, expression, and discovery
14:
4364:
3553:Cholesterylester transfer protein
3403:Chondroitin sulfate proteoglycans
3097:
1212:. Hemopexin preserves the body's
1049:that in humans is encoded by the
1684:"Bilirubin and hemolytic anemia"
502:
495:
257:
250:
244:
221:
156:
149:
143:
118:
2221:
2030:
1943:
1892:
1816:
1789:
1774:
1715:
1711:Orthosatic intolerance - 604715
1700:
4140:Extracellular matrix protein 1
2937:Journal of Cellular Physiology
2486:Journal of Molecular Evolution
1471:Journal of Molecular Evolution
1430:
1412:
1271:. High hemopexin level in the
1158:Cai and Law (1986) prepared a
513:More reference expression data
475:More reference expression data
383:olfactory zone of nasal mucosa
375:right hemisphere of cerebellum
1:
3044:10.1016/S0304-3835(99)00367-5
3015:10.1016/S0891-5849(99)00082-9
2839:10.1016/S0021-9258(18)53184-7
2655:10.1016/S0021-9258(18)68467-4
2591:10.1016/S0021-9258(18)47465-0
2468:10.1016/S0021-9258(18)60703-3
2079:Current Opinion in Lipidology
1958:(3): 537–41, discussion 542.
1588:10.1016/s0969-2126(01)00185-x
1364:
1316:erythropoietic protoporphyria
1104:, the latter always binds to
663:cellular iron ion homeostasis
648:receptor-mediated endocytosis
242:
141:
4338:Genes on human chromosome 11
3871:Sex hormone-binding globulin
3061:Journal of Protein Chemistry
2911:10.1016/0014-5793(96)00225-6
2869:10.1016/0304-3940(93)90756-B
2796:10.1016/0014-5793(84)80603-1
2621:10.1016/0888-7543(88)90158-9
2397:10.1016/0005-2795(78)90447-6
2346:Journal of Leukocyte Biology
2183:Journal of Neuroinflammation
2147:10.1161/strokeaha.115.011956
2091:10.1097/MOL.0000000000000208
1964:10.1097/HJH.0b013e32835c1727
1456:"Entrez Gene: HPX hemopexin"
1100:Hemopexin is different from
1071:in the blood plasma (called
653:hemoglobin metabolic process
7:
4286:Haptoglobin-related protein
3650:Tumor necrosis factor alpha
2015:10.1182/blood.V32.5.811.811
1349:Haptoglobin-related protein
1337:
1312:autoimmune hemolytic anemia
1228:II Type 1 receptor (AT1-R)
1187:
10:
4369:
3640:Thyroxine-binding proteins
1878:10.1089/104454902753759717
1842:10.1182/blood-2005-03-1185
1633:10.1089/104454902753759717
1320:pyruvate kinase deficiency
453:sexually immature organism
399:mucosa of transverse colon
15:
4304:
4233:
4210:
4152:
4135:Vitamin D-binding protein
4102:
4074:
4046:
4037:
3994:
3950:
3932:
3885:
3858:
3849:
3814:
3779:
3729:
3720:
3708:
3603:Serum amyloid P component
3563:Colony-stimulating factor
3500:
3478:
3450:
3393:
3366:
3334:
3325:
3280:
3172:
3163:
2196:10.1186/s12974-016-0490-1
1660:"Intravascular hemolysis"
1438:"Mouse PubMed Reference:"
1420:"Human PubMed Reference:"
1269:intracerebral haemorrhage
1154:Mapping of hemopexin gene
1013:
1008:
1004:
997:
981:
975:Chr 7: 105.24 – 105.25 Mb
962:
947:
943:
926:
922:
915:
900:
896:
879:
875:
868:
855:
851:
836:
832:
823:
810:
806:
791:
787:
778:
765:
761:
746:
742:
733:
718:
711:
707:
691:
561:metallopeptidase activity
531:
527:
510:
494:
485:
472:
421:
412:
391:Descending thoracic aorta
359:
350:
320:
312:
308:
291:
278:
241:
220:
211:
207:
190:
177:
140:
117:
108:
104:
59:
56:
46:
39:
34:
30:
25:
4241:Alpha 1-antichymotrypsin
3746:Alpha 1-antichymotrypsin
3543:B-cell activating factor
3518:Alpha 1-antichymotrypsin
3108:Medical Subject Headings
2304:10.3389/fphys.2014.00415
1258:cerebral ischemic injury
4029:7S seed storage protein
3806:Retinol binding protein
3073:10.1023/A:1007016105813
2291:Frontiers in Physiology
1952:Journal of Hypertension
1918:10.1074/jbc.m109.017202
1298:Relation to haptoglobin
1277:subarachnoid hemorrhage
1243:intravascular hemolytic
582:endocytic vesicle lumen
3578:Membrane glycoproteins
2751:10.1073/pnas.81.7.2021
2547:10.1093/nar/13.11.3841
2535:Nucleic Acids Research
2254:10.1126/sciadv.adc9245
1538:10.1093/nar/13.11.3841
1526:Nucleic Acids Research
1250:cardiovascular disease
968:Chr 11: 6.43 – 6.44 Mb
668:heme metabolic process
4251:Alpha 2-macroglobulin
3832:alpha-2-Macroglobulin
2414:Acta Neuropathologica
2041:Essential Haematology
1236:Clinical significance
1173:in situ hybridization
587:extracellular exosome
379:right coronary artery
134:Chromosome 11 (human)
4204:Acute-phase proteins
4089:Bovine serum albumin
3905:Beta-2 microglobulin
2857:Neuroscience Letters
2698:10.1073/pnas.82.1.73
1866:DNA and Cell Biology
1749:10.1073/pnas.82.1.73
1621:DNA and Cell Biology
1569:Bode W (June 1995).
1043:beta-1B-glycoprotein
577:extracellular region
236:Chromosome 7 (mouse)
4246:Alpha 1-antitrypsin
4084:Human serum albumin
4024:11S globulin family
3770:Heparin cofactor II
3760:Alpha 2-antiplasmin
3750:Alpha 1-antitrypsin
3583:Myelin protein zero
3508:Activin and inhibin
3308:Phytohaemagglutinin
2742:1984PNAS...81.2021T
2689:1985PNAS...82...73T
2498:1988JMolE..27..102A
2359:10.1189/jlb.1006629
2246:2022SciA....8C9245L
1785:Hemopexin - 142290
1740:1985PNAS...82...73T
1483:1988JMolE..27..102A
1304:sickle cell disease
1273:cerebrospinal fluid
1056:and belongs to the
597:extracellular space
592:blood microparticle
433:right lobe of liver
363:right lobe of liver
4256:C-reactive protein
4110:C-reactive protein
4002:Beta-lactoglobulin
3533:Asialoglycoprotein
2506:10.1007/BF02138368
2426:10.1007/BF00687397
1491:10.1007/BF02138368
1162:for hemopexin, by
813:ENSMUSG00000030895
611:Biological process
570:Cellular component
539:Molecular function
425:left lobe of liver
367:right uterine tube
4325:
4324:
4170:
4169:
4148:
4147:
4119:Alpha-lactalbumin
4019:Alpha-lactalbumin
3990:
3989:
3962:Fetal fibronectin
3928:
3927:
3845:
3844:
3702:Globular proteins
3668:
3667:
3608:Sialoglycoprotein
3496:
3495:
3437:Platelet factor 4
3321:
3320:
2986:10.1021/bi960737u
2056:978-1-4051-3649-5
1911:(27): 18292–301.
1125:disulfide bridges
1041:), also known as
1024:
1023:
1020:
1019:
993:
992:
958:
957:
937:
936:
911:
910:
890:
889:
864:
863:
845:
844:
819:
818:
800:
799:
774:
773:
755:
754:
703:
702:
556:metal ion binding
523:
522:
519:
518:
481:
480:
468:
467:
406:
405:
304:
303:
203:
202:
4360:
4197:
4190:
4183:
4174:
4173:
4044:
4043:
3888:
3864:
3861:carrier proteins
3856:
3855:
3817:
3785:
3782:carrier proteins
3735:
3727:
3726:
3718:
3717:
3695:
3688:
3681:
3672:
3671:
3523:Apolipoprotein H
3332:
3331:
3293:Intrinsic factor
3170:
3169:
3138:
3131:
3124:
3115:
3114:
3092:
3055:
3026:
2997:
2968:
2931:
2913:
2888:
2851:
2841:
2816:
2798:
2773:
2763:
2753:
2720:
2710:
2700:
2667:
2657:
2632:
2603:
2593:
2568:
2558:
2525:
2480:
2470:
2445:
2408:
2379:
2361:
2327:
2326:
2316:
2306:
2282:
2276:
2275:
2265:
2240:(51): eadc9245.
2234:Science Advances
2225:
2219:
2218:
2208:
2198:
2174:
2168:
2167:
2149:
2131:
2122:
2113:
2112:
2102:
2070:
2061:
2060:
2044:
2034:
2028:
2027:
2017:
1993:
1984:
1983:
1947:
1941:
1940:
1930:
1920:
1896:
1890:
1889:
1861:
1855:
1854:
1844:
1820:
1814:
1813:
1793:
1787:
1778:
1772:
1771:
1761:
1751:
1719:
1713:
1704:
1698:
1697:
1695:
1694:
1680:
1674:
1673:
1671:
1670:
1656:
1645:
1644:
1616:
1601:
1600:
1590:
1566:
1560:
1559:
1549:
1517:
1511:
1510:
1466:
1460:
1459:
1452:
1446:
1445:
1434:
1428:
1427:
1416:
1410:
1400:
1389:
1379:
1192:Hemopexin binds
1171:gene complex by
1058:hemopexin family
1006:
1005:
977:
970:
953:
941:
940:
932:
920:
919:
916:RefSeq (protein)
906:
894:
893:
885:
873:
872:
849:
848:
830:
829:
804:
803:
785:
784:
759:
758:
740:
739:
709:
708:
529:
528:
515:
506:
499:
492:
491:
477:
417:
415:Top expressed in
410:
409:
355:
353:Top expressed in
348:
347:
327:
326:
310:
309:
300:
287:
276:
261:
254:
248:
237:
225:
209:
208:
199:
186:
175:
160:
153:
147:
136:
122:
106:
105:
100:
51:
44:
23:
22:
18:hemopexin family
4368:
4367:
4363:
4362:
4361:
4359:
4358:
4357:
4328:
4327:
4326:
4321:
4300:
4229:
4206:
4201:
4171:
4166:
4165:
4144:
4098:
4070:
4033:
3995:Other globulins
3986:
3946:
3942:Immunoglobulins
3924:
3886:
3881:
3878:
3859:
3841:
3815:
3810:
3780:
3775:
3730:
3722:Alpha globulins
3704:
3699:
3669:
3664:
3492:
3474:
3446:
3389:
3362:
3317:
3276:
3159:
3142:
3100:
3095:
2980:(40): 13112–7.
2832:(10): 7365–71.
2648:(17): 8226–31.
2584:(18): 8668–71.
2541:(11): 3841–59.
2335:
2333:Further reading
2330:
2283:
2279:
2226:
2222:
2175:
2171:
2129:
2123:
2116:
2071:
2064:
2057:
2035:
2031:
1994:
1987:
1948:
1944:
1897:
1893:
1862:
1858:
1821:
1817:
1794:
1790:
1779:
1775:
1720:
1716:
1705:
1701:
1692:
1690:
1682:
1681:
1677:
1668:
1666:
1658:
1657:
1648:
1617:
1604:
1567:
1563:
1532:(11): 3841–59.
1518:
1514:
1467:
1463:
1454:
1453:
1449:
1436:
1435:
1431:
1418:
1417:
1413:
1401:
1392:
1380:
1371:
1367:
1340:
1300:
1238:
1190:
1181:
1156:
1136:oligosaccharide
1121:
1073:free hemoglobin
1015:View/Edit Mouse
1010:View/Edit Human
973:
966:
963:Location (UCSC)
949:
928:
902:
881:
794:ENSG00000110169
687:
606:
565:
551:protein binding
511:
501:
500:
473:
464:
459:
455:
451:
447:
443:
439:
435:
431:
427:
413:
402:
397:
393:
389:
385:
381:
377:
373:
369:
365:
351:
295:
282:
274:
264:
263:
262:
255:
235:
212:Gene location (
194:
181:
173:
163:
162:
161:
154:
132:
109:Gene location (
98:HPX - orthologs
60:
52:, HX, hemopexin
47:
40:
21:
12:
11:
5:
4366:
4356:
4355:
4350:
4345:
4343:Blood proteins
4340:
4323:
4322:
4320:
4319:
4314:
4308:
4306:
4302:
4301:
4299:
4298:
4293:
4288:
4283:
4278:
4273:
4268:
4263:
4258:
4253:
4248:
4243:
4237:
4235:
4234:Other positive
4231:
4230:
4228:
4227:
4222:
4216:
4214:
4208:
4207:
4200:
4199:
4192:
4185:
4177:
4168:
4167:
4164:
4163:
4154:
4153:
4150:
4149:
4146:
4145:
4143:
4142:
4137:
4132:
4127:
4122:
4112:
4106:
4104:
4100:
4099:
4097:
4096:
4091:
4086:
4080:
4078:
4072:
4071:
4069:
4068:
4063:
4058:
4052:
4050:
4041:
4035:
4034:
4032:
4031:
4026:
4021:
4016:
4011:
4010:
4009:
3998:
3996:
3992:
3991:
3988:
3987:
3985:
3984:
3979:
3977:Transcobalamin
3974:
3965:
3954:
3952:
3948:
3947:
3945:
3944:
3938:
3936:
3934:Gamma globulin
3930:
3929:
3926:
3925:
3923:
3922:
3917:
3912:
3907:
3902:
3897:
3891:
3889:
3883:
3882:
3880:
3879:
3873:
3867:
3865:
3853:
3851:Beta globulins
3847:
3846:
3843:
3842:
3840:
3839:
3828:
3820:
3818:
3812:
3811:
3809:
3808:
3803:
3796:
3788:
3786:
3777:
3776:
3774:
3773:
3763:
3753:
3738:
3736:
3724:
3715:
3706:
3705:
3698:
3697:
3690:
3683:
3675:
3666:
3665:
3663:
3662:
3657:
3652:
3647:
3642:
3637:
3632:
3630:Thrombopoietin
3627:
3626:
3625:
3620:
3615:
3605:
3600:
3595:
3590:
3585:
3580:
3575:
3570:
3565:
3560:
3555:
3550:
3545:
3540:
3535:
3530:
3525:
3520:
3515:
3510:
3504:
3502:
3498:
3497:
3494:
3493:
3491:
3490:
3484:
3482:
3476:
3475:
3473:
3472:
3467:
3462:
3456:
3454:
3448:
3447:
3445:
3444:
3439:
3434:
3429:
3424:
3419:
3414:
3409:
3399:
3397:
3391:
3390:
3388:
3387:
3382:
3376:
3374:
3364:
3363:
3361:
3360:
3355:
3350:
3344:
3342:
3329:
3323:
3322:
3319:
3318:
3316:
3315:
3310:
3305:
3300:
3295:
3290:
3284:
3282:
3278:
3277:
3275:
3274:
3269:
3264:
3259:
3254:
3249:
3244:
3239:
3234:
3229:
3224:
3219:
3214:
3209:
3204:
3199:
3194:
3189:
3184:
3178:
3176:
3167:
3161:
3160:
3149:glycoconjugate
3141:
3140:
3133:
3126:
3118:
3112:
3111:
3099:
3098:External links
3096:
3094:
3093:
3056:
3038:(1–2): 221–6.
3032:Cancer Letters
3027:
3009:(1–2): 214–9.
2998:
2969:
2932:
2889:
2852:
2817:
2774:
2721:
2668:
2633:
2604:
2569:
2526:
2481:
2461:(11): 5224–9.
2446:
2409:
2380:
2336:
2334:
2331:
2329:
2328:
2277:
2220:
2169:
2114:
2062:
2055:
2029:
1985:
1942:
1891:
1872:(4): 297–306.
1856:
1815:
1788:
1773:
1714:
1699:
1675:
1646:
1627:(4): 297–306.
1602:
1561:
1512:
1461:
1447:
1429:
1411:
1390:
1368:
1366:
1363:
1362:
1361:
1356:
1351:
1346:
1339:
1336:
1299:
1296:
1288:cardiotoxicity
1237:
1234:
1189:
1186:
1180:
1177:
1155:
1152:
1129:amino-terminal
1120:
1117:
1077:met-hemoglobin
1022:
1021:
1018:
1017:
1012:
1002:
1001:
995:
994:
991:
990:
988:
986:
979:
978:
971:
964:
960:
959:
956:
955:
945:
944:
938:
935:
934:
924:
923:
917:
913:
912:
909:
908:
898:
897:
891:
888:
887:
877:
876:
870:
866:
865:
862:
861:
853:
852:
846:
843:
842:
834:
833:
827:
821:
820:
817:
816:
808:
807:
801:
798:
797:
789:
788:
782:
776:
775:
772:
771:
763:
762:
756:
753:
752:
744:
743:
737:
731:
730:
725:
720:
716:
715:
705:
704:
701:
700:
689:
688:
686:
685:
680:
675:
670:
665:
660:
658:heme transport
655:
650:
645:
640:
635:
630:
625:
620:
614:
612:
608:
607:
605:
604:
599:
594:
589:
584:
579:
573:
571:
567:
566:
564:
563:
558:
553:
548:
542:
540:
536:
535:
525:
524:
521:
520:
517:
516:
508:
507:
489:
483:
482:
479:
478:
470:
469:
466:
465:
463:
462:
458:
454:
450:
449:pyloric antrum
446:
442:
438:
434:
430:
426:
422:
419:
418:
407:
404:
403:
401:
400:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
357:
356:
344:
343:
335:
324:
318:
317:
314:RNA expression
306:
305:
302:
301:
293:
289:
288:
280:
277:
272:
266:
265:
256:
249:
243:
239:
238:
233:
227:
226:
218:
217:
205:
204:
201:
200:
192:
188:
187:
179:
176:
171:
165:
164:
155:
148:
142:
138:
137:
130:
124:
123:
115:
114:
102:
101:
58:
54:
53:
45:
37:
36:
32:
31:
28:
27:
9:
6:
4:
3:
2:
4365:
4354:
4351:
4349:
4346:
4344:
4341:
4339:
4336:
4335:
4333:
4318:
4315:
4313:
4312:Serum albumin
4310:
4309:
4307:
4303:
4297:
4294:
4292:
4289:
4287:
4284:
4282:
4279:
4277:
4274:
4272:
4269:
4267:
4264:
4262:
4261:Ceruloplasmin
4259:
4257:
4254:
4252:
4249:
4247:
4244:
4242:
4239:
4238:
4236:
4232:
4226:
4223:
4221:
4218:
4217:
4215:
4213:
4209:
4205:
4198:
4193:
4191:
4186:
4184:
4179:
4178:
4175:
4162:
4159:
4156:
4155:
4151:
4141:
4138:
4136:
4133:
4131:
4128:
4126:
4123:
4120:
4116:
4113:
4111:
4108:
4107:
4105:
4101:
4095:
4092:
4090:
4087:
4085:
4082:
4081:
4079:
4077:
4076:Serum albumin
4073:
4067:
4064:
4062:
4059:
4057:
4054:
4053:
4051:
4049:
4045:
4042:
4040:
4036:
4030:
4027:
4025:
4022:
4020:
4017:
4015:
4014:Thyroglobulin
4012:
4008:
4005:
4004:
4003:
4000:
3999:
3997:
3993:
3983:
3980:
3978:
3975:
3973:
3972:Microglobulin
3969:
3968:Macroglobulin
3966:
3963:
3959:
3956:
3955:
3953:
3949:
3943:
3940:
3939:
3937:
3935:
3931:
3921:
3918:
3916:
3913:
3911:
3908:
3906:
3903:
3901:
3898:
3896:
3893:
3892:
3890:
3884:
3877:
3874:
3872:
3869:
3868:
3866:
3862:
3857:
3854:
3852:
3848:
3837:
3833:
3829:
3826:
3822:
3821:
3819:
3813:
3807:
3804:
3801:
3800:Ceruloplasmin
3797:
3794:
3790:
3789:
3787:
3783:
3778:
3771:
3767:
3764:
3761:
3757:
3754:
3751:
3747:
3743:
3740:
3739:
3737:
3733:
3728:
3725:
3723:
3719:
3716:
3714:
3711:
3707:
3703:
3696:
3691:
3689:
3684:
3682:
3677:
3676:
3673:
3661:
3658:
3656:
3653:
3651:
3648:
3646:
3643:
3641:
3638:
3636:
3635:Thyroglobulin
3633:
3631:
3628:
3624:
3623:Glycophorin C
3621:
3619:
3616:
3614:
3611:
3610:
3609:
3606:
3604:
3601:
3599:
3596:
3594:
3591:
3589:
3586:
3584:
3581:
3579:
3576:
3574:
3571:
3569:
3566:
3564:
3561:
3559:
3556:
3554:
3551:
3549:
3546:
3544:
3541:
3539:
3536:
3534:
3531:
3529:
3526:
3524:
3521:
3519:
3516:
3514:
3511:
3509:
3506:
3505:
3503:
3499:
3489:
3486:
3485:
3483:
3481:
3477:
3471:
3468:
3466:
3463:
3461:
3458:
3457:
3455:
3453:
3449:
3443:
3440:
3438:
3435:
3433:
3430:
3428:
3425:
3423:
3420:
3418:
3415:
3413:
3410:
3408:
3404:
3401:
3400:
3398:
3396:
3392:
3386:
3383:
3381:
3378:
3377:
3375:
3373:
3369:
3365:
3359:
3356:
3354:
3351:
3349:
3346:
3345:
3343:
3341:
3337:
3333:
3330:
3328:
3327:Proteoglycans
3324:
3314:
3311:
3309:
3306:
3304:
3303:Peptidoglycan
3301:
3299:
3296:
3294:
3291:
3289:
3286:
3285:
3283:
3279:
3273:
3270:
3268:
3265:
3263:
3260:
3258:
3255:
3253:
3250:
3248:
3245:
3243:
3240:
3238:
3235:
3233:
3230:
3228:
3225:
3223:
3220:
3218:
3215:
3213:
3210:
3208:
3205:
3203:
3200:
3198:
3195:
3193:
3190:
3188:
3185:
3183:
3180:
3179:
3177:
3175:
3171:
3168:
3166:
3162:
3158:
3157:glycopeptides
3154:
3153:glycoproteins
3150:
3146:
3139:
3134:
3132:
3127:
3125:
3120:
3119:
3116:
3109:
3105:
3102:
3101:
3090:
3086:
3082:
3078:
3074:
3070:
3067:(3): 239–48.
3066:
3062:
3057:
3053:
3049:
3045:
3041:
3037:
3033:
3028:
3024:
3020:
3016:
3012:
3008:
3004:
2999:
2995:
2991:
2987:
2983:
2979:
2975:
2970:
2966:
2962:
2958:
2954:
2950:
2946:
2942:
2938:
2933:
2929:
2925:
2921:
2917:
2912:
2907:
2904:(1–2): 72–4.
2903:
2899:
2895:
2890:
2886:
2882:
2878:
2874:
2870:
2866:
2862:
2858:
2853:
2849:
2845:
2840:
2835:
2831:
2827:
2823:
2818:
2814:
2810:
2806:
2802:
2797:
2792:
2788:
2784:
2780:
2775:
2771:
2767:
2762:
2757:
2752:
2747:
2743:
2739:
2736:(7): 2021–5.
2735:
2731:
2727:
2722:
2718:
2714:
2709:
2704:
2699:
2694:
2690:
2686:
2682:
2678:
2674:
2669:
2665:
2661:
2656:
2651:
2647:
2643:
2639:
2634:
2630:
2626:
2622:
2618:
2614:
2610:
2605:
2601:
2597:
2592:
2587:
2583:
2579:
2575:
2570:
2566:
2562:
2557:
2552:
2548:
2544:
2540:
2536:
2532:
2527:
2523:
2519:
2515:
2511:
2507:
2503:
2499:
2495:
2491:
2487:
2482:
2478:
2474:
2469:
2464:
2460:
2456:
2452:
2447:
2443:
2439:
2435:
2431:
2427:
2423:
2419:
2415:
2410:
2406:
2402:
2398:
2394:
2390:
2386:
2381:
2377:
2373:
2369:
2365:
2360:
2355:
2352:(4): 870–92.
2351:
2347:
2343:
2338:
2337:
2324:
2320:
2315:
2310:
2305:
2300:
2296:
2292:
2288:
2281:
2273:
2269:
2264:
2259:
2255:
2251:
2247:
2243:
2239:
2235:
2231:
2224:
2216:
2212:
2207:
2202:
2197:
2192:
2188:
2184:
2180:
2173:
2165:
2161:
2157:
2153:
2148:
2143:
2139:
2135:
2128:
2121:
2119:
2110:
2106:
2101:
2096:
2092:
2088:
2084:
2080:
2076:
2069:
2067:
2058:
2052:
2048:
2043:
2042:
2033:
2025:
2021:
2016:
2011:
2007:
2003:
1999:
1992:
1990:
1981:
1977:
1973:
1969:
1965:
1961:
1957:
1953:
1946:
1938:
1934:
1929:
1924:
1919:
1914:
1910:
1906:
1902:
1895:
1887:
1883:
1879:
1875:
1871:
1867:
1860:
1852:
1848:
1843:
1838:
1835:(7): 2572–9.
1834:
1830:
1826:
1819:
1811:
1807:
1804:(5): 355–60.
1803:
1799:
1792:
1786:
1782:
1777:
1769:
1765:
1760:
1755:
1750:
1745:
1741:
1737:
1733:
1729:
1725:
1718:
1712:
1708:
1703:
1689:
1685:
1679:
1665:
1661:
1655:
1653:
1651:
1642:
1638:
1634:
1630:
1626:
1622:
1615:
1613:
1611:
1609:
1607:
1598:
1594:
1589:
1584:
1581:(6): 527–30.
1580:
1576:
1572:
1565:
1557:
1553:
1548:
1543:
1539:
1535:
1531:
1527:
1523:
1516:
1508:
1504:
1500:
1496:
1492:
1488:
1484:
1480:
1476:
1472:
1465:
1457:
1451:
1443:
1439:
1433:
1425:
1421:
1415:
1408:
1404:
1399:
1397:
1395:
1387:
1383:
1378:
1376:
1374:
1369:
1360:
1357:
1355:
1352:
1350:
1347:
1345:
1342:
1341:
1335:
1333:
1329:
1325:
1321:
1317:
1313:
1309:
1308:spherocytosis
1305:
1295:
1293:
1292:heart failure
1289:
1285:
1284:anthracycline
1280:
1278:
1274:
1270:
1265:
1263:
1259:
1255:
1251:
1247:
1244:
1233:
1231:
1227:
1223:
1219:
1215:
1211:
1207:
1203:
1199:
1195:
1185:
1176:
1174:
1170:
1165:
1164:Southern blot
1161:
1151:
1148:
1143:
1141:
1137:
1134:
1133:galactosamine
1130:
1126:
1116:
1114:
1110:
1107:
1103:
1098:
1095:
1093:
1089:
1085:
1082:
1078:
1074:
1070:
1066:
1061:
1059:
1055:
1052:
1048:
1044:
1040:
1036:
1032:
1028:
1016:
1011:
1007:
1003:
1000:
996:
989:
987:
984:
980:
976:
972:
969:
965:
961:
954:
952:
946:
942:
939:
933:
931:
925:
921:
918:
914:
907:
905:
899:
895:
892:
886:
884:
878:
874:
871:
869:RefSeq (mRNA)
867:
860:
859:
854:
850:
847:
841:
840:
835:
831:
828:
826:
822:
815:
814:
809:
805:
802:
796:
795:
790:
786:
783:
781:
777:
770:
769:
764:
760:
757:
751:
750:
745:
741:
738:
736:
732:
729:
726:
724:
721:
717:
714:
710:
706:
699:
695:
690:
684:
681:
679:
676:
674:
671:
669:
666:
664:
661:
659:
656:
654:
651:
649:
646:
644:
641:
639:
638:viral process
636:
634:
631:
629:
626:
624:
621:
619:
616:
615:
613:
610:
609:
603:
600:
598:
595:
593:
590:
588:
585:
583:
580:
578:
575:
574:
572:
569:
568:
562:
559:
557:
554:
552:
549:
547:
544:
543:
541:
538:
537:
534:
533:Gene ontology
530:
526:
514:
509:
505:
498:
493:
490:
488:
484:
476:
471:
460:
456:
452:
448:
444:
440:
436:
432:
428:
424:
423:
420:
416:
411:
408:
398:
394:
390:
386:
382:
378:
374:
370:
366:
362:
361:
358:
354:
349:
346:
345:
342:
340:
336:
334:
333:
329:
328:
325:
323:
319:
315:
311:
307:
299:
294:
290:
286:
281:
271:
267:
260:
253:
247:
240:
232:
228:
224:
219:
215:
210:
206:
198:
193:
189:
185:
180:
170:
166:
159:
152:
146:
139:
135:
129:
125:
121:
116:
112:
107:
103:
99:
95:
91:
87:
83:
79:
75:
71:
67:
63:
55:
50:
43:
38:
33:
29:
24:
19:
4353:Orphan drugs
4290:
4157:
3899:
3766:Antithrombin
3567:
3548:4-1BB ligand
3460:Fibromodulin
3165:Mucoproteins
3064:
3060:
3035:
3031:
3006:
3002:
2977:
2974:Biochemistry
2973:
2943:(1): 71–80.
2940:
2936:
2901:
2898:FEBS Letters
2897:
2863:(2): 141–4.
2860:
2856:
2829:
2825:
2789:(2): 213–6.
2786:
2783:FEBS Letters
2782:
2733:
2729:
2680:
2676:
2645:
2641:
2615:(1): 48–52.
2612:
2608:
2581:
2577:
2538:
2534:
2492:(2): 102–8.
2489:
2485:
2458:
2454:
2420:(1): 16–21.
2417:
2413:
2391:(1): 57–64.
2388:
2384:
2349:
2345:
2294:
2290:
2280:
2237:
2233:
2223:
2186:
2182:
2172:
2140:(3): 872–6.
2137:
2133:
2085:(5): 384–7.
2082:
2078:
2040:
2032:
2008:(5): 811–5.
2005:
2001:
1955:
1951:
1945:
1908:
1904:
1894:
1869:
1865:
1859:
1832:
1828:
1818:
1801:
1797:
1791:
1776:
1731:
1727:
1717:
1702:
1691:. Retrieved
1687:
1678:
1667:. Retrieved
1663:
1624:
1620:
1578:
1574:
1564:
1529:
1525:
1515:
1477:(2): 102–8.
1474:
1470:
1464:
1450:
1441:
1432:
1423:
1414:
1301:
1281:
1266:
1254:septic shock
1239:
1229:
1191:
1182:
1157:
1144:
1122:
1105:
1099:
1096:
1088:globin chain
1080:
1072:
1068:
1067:circulating
1064:
1062:
1050:
1047:glycoprotein
1042:
1038:
1034:
1030:
1026:
1025:
948:
927:
901:
880:
856:
837:
811:
792:
766:
747:
727:
722:
395:tibial nerve
337:
330:
296:105,249,344
283:105,240,820
57:External IDs
4317:Transferrin
4296:Orosomucoid
4281:Haptoglobin
4125:Parvalbumin
4115:Lactalbumin
4007:Lactoferrin
3958:Fibronectin
3915:Plasminogen
3895:Angiostatin
3876:Transferrin
3836:Haptoglobin
3825:Orosomucoid
3793:Transcortin
3660:Vitronectin
3655:Uteroglobin
3645:Transcortin
3618:Glycophorin
3588:Osteonectin
3573:Lactoferrin
3298:Orosomucoid
3288:Haptoglobin
2683:(1): 73–7.
1734:(1): 73–7.
1344:Haptoglobin
1324:haptoglobin
1226:angiotensin
1222:haptoglobin
1169:beta-globin
1102:haptoglobin
1086:along with
1063:Hemoglobin
683:proteolysis
445:human fetus
429:gallbladder
275:7|7 E3
35:Identifiers
4332:Categories
4094:Prealbumin
4056:Conalbumin
3488:Syndecan 1
1693:2019-05-08
1669:2019-05-08
1409:, May 2017
1388:, May 2017
1365:References
1359:Hemoglobin
1332:macrophage
1202:hemoglobin
1160:cDNA clone
1140:homologous
1109:hemoglobin
1031:haemopexin
341:(ortholog)
195:6,442,617
182:6,431,049
78:HomoloGene
4291:Hemopexin
4061:Ovalbumin
4048:Egg white
3920:Properdin
3900:Hemopexin
3830:alpha-2 (
3823:alpha-1 (
3798:alpha-2 (
3791:alpha-1 (
3713:globulins
3598:Protein S
3593:Protein C
3568:Hemopexin
3558:Clusterin
3470:Keratocan
3104:Hemopexin
1688:eClinpath
1664:eClinpath
1575:Structure
1286:-induced
1027:Hemopexin
951:NP_059067
930:NP_000604
904:NM_017371
883:NM_000613
713:Orthologs
678:transport
86:GeneCards
4305:Negative
4271:Ferritin
4158:see also
4039:Albumins
3910:Factor H
3417:Brevican
3412:Neurocan
3407:Aggrecan
3385:Perlecan
3380:Testican
3358:Versican
3353:Biglycan
3313:Ovomucin
3089:45510572
3081:10981817
3052:10737728
3023:10443938
2965:10105569
2928:21283343
2885:24743139
2813:45009902
2609:Genomics
2522:11271490
2442:24415663
2376:16210789
2368:17185359
2323:25389409
2272:36563141
2215:26831741
2164:11532383
2156:26768209
2109:26339767
1980:23501030
1972:23254305
1937:19433579
1886:12042069
1851:15947085
1783:(OMIM):
1709:(OMIM):
1641:12042069
1507:11271490
1405:–
1384:–
1338:See also
1328:monocyte
1230:in vitro
1188:Function
999:Wikidata
692:Sources:
371:testicle
4212:Amyloid
3982:Edestin
3756:alpha-2
3742:alpha-1
3732:serpins
3465:Lumican
3348:Decorin
3145:Protein
2994:8855948
2957:8647924
2920:8612795
2877:8474687
2848:8463269
2805:6510521
2770:6371807
2738:Bibcode
2717:3855550
2685:Bibcode
2664:3372522
2629:3220477
2600:3036819
2565:2989777
2514:2842511
2494:Bibcode
2477:2833500
2434:2735186
2314:4211382
2297:: 415.
2263:9788780
2242:Bibcode
2206:4736638
2100:4826275
2024:5687939
1928:2709397
1810:3026994
1768:3855550
1736:Bibcode
1597:8590012
1556:2989777
1499:2842511
1479:Bibcode
1407:Ensembl
1386:Ensembl
1198:protein
1111:. (See
1045:, is a
825:UniProt
780:Ensembl
719:Species
698:QuickGO
316:pattern
174:11p15.4
42:Aliases
4276:Fibrin
4066:Avidin
3960:(fFN:
3887:other:
3816:other:
3538:Avidin
3217:MUC5AC
3110:(MeSH)
3087:
3079:
3050:
3021:
2992:
2963:
2955:
2926:
2918:
2883:
2875:
2846:
2811:
2803:
2768:
2761:345428
2758:
2715:
2708:396973
2705:
2662:
2627:
2598:
2563:
2556:341281
2553:
2520:
2512:
2475:
2440:
2432:
2405:620056
2403:
2374:
2366:
2321:
2311:
2270:
2260:
2213:
2203:
2189:: 26.
2162:
2154:
2134:Stroke
2107:
2097:
2053:
2022:
1978:
1970:
1935:
1925:
1884:
1849:
1808:
1766:
1759:396973
1756:
1639:
1595:
1554:
1547:341281
1544:
1505:
1497:
1290:(e.g.
1260:, and
1246:anemia
1206:ligand
1065:itself
985:search
983:PubMed
858:Q91X72
839:P02790
735:Entrez
487:BioGPS
461:embryo
457:embryo
437:morula
74:105112
66:142290
4130:Ricin
4103:Other
3951:Other
3710:Serum
3501:Other
3432:CSPG5
3427:CSPG4
3281:Other
3272:MUC20
3267:MUC19
3262:MUC17
3257:MUC16
3252:MUC15
3247:MUC13
3242:MUC12
3222:MUC5B
3207:MUC3B
3202:MUC3A
3187:CD164
3174:Mucin
3085:S2CID
2961:S2CID
2924:S2CID
2881:S2CID
2809:S2CID
2518:S2CID
2438:S2CID
2372:S2CID
2160:S2CID
2130:(PDF)
2002:Blood
1976:S2CID
1829:Blood
1503:S2CID
1218:Bach1
1147:exons
1069:alone
768:15458
728:Mouse
723:Human
694:Amigo
387:gonad
339:Mouse
332:Human
279:Start
214:Mouse
178:Start
111:Human
3613:CD43
3528:CD70
3513:ADAM
3422:CD44
3237:MUC8
3232:MUC7
3227:MUC6
3212:MUC4
3197:MUC2
3192:MUC1
3182:CD43
3155:and
3077:PMID
3048:PMID
3019:PMID
2990:PMID
2953:PMID
2916:PMID
2873:PMID
2844:PMID
2801:PMID
2766:PMID
2713:PMID
2660:PMID
2625:PMID
2596:PMID
2561:PMID
2510:PMID
2473:PMID
2430:PMID
2401:PMID
2364:PMID
2319:PMID
2268:PMID
2211:PMID
2152:PMID
2105:PMID
2051:ISBN
2020:PMID
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