188:
239:. He showed evidence for it with experiments with two different variations of virus, and once he had passed the viruses through a host it would change the selectivity making it almost impossible for one of the two original variations to grow and spread. It is a process that does not involve mutation and selection. Bertani assumed that a phage existed that was almost entirely based on the host and was used in replication that created these host control variations.
223:
strain. Using these, he was able to show that the production of phages by a lysogen was discontinuous and involved rare, large bursts of phage. His further studies into the
Lisbonne strain of
448:
207:, a professor at Indiana university, and joined him as a research associate. It was here that he requested Luria to give him the opportunity to study
195:
In 1948, around the time
Bertani turned 25 years old, he immigrated to the United states as Carnegie Fellow. He was invited to work in a group with
187:
257:
443:
136:
144:
428:
235:
In 1953, Bertani was one of the first scientist to describe host controlled variation along side his colleague
104:
335:
168:
334:
Ezraty, Benjamin; Henry, Camille; Hérisse, Marion; Denamur, Erick; Barras, Frédéric (2014-09-01).
91:
24:
199:. He quickly shifted from his work in Drosophila genetics to become a pioneer in the field of
438:
433:
172:
164:
152:
8:
66:
351:
311:
286:
200:
135:, he met Elizabeth Teegarden who eventually became his wife. In 1954 he transferred to
124:
112:
399:
374:
404:
355:
316:
394:
386:
347:
306:
298:
213:
196:
100:
34:
302:
390:
140:
336:"Commercial Lysogeny Broth culture media and oxidative stress: A cautious tale"
236:
204:
46:
22:(October 23, 1923–April 7, 2015) was a microbial geneticist who did work with
422:
359:
120:
39:
29:
408:
320:
167:
during this time. In 1981 he resigned as professor and went to work at the
160:
96:
127:
as a research associate with
Salvador Luria and began deeper studies into
148:
108:
58:
176:
65:
with his family. After completing elementary school he studied at the
258:"Luria Broth (LB) and Luria Agar (LA) Media and Their Uses Protocol"
82:
219:
208:
132:
128:
86:
70:
74:
156:
78:
62:
89:
studies. There he did research on developmental problems in
333:
73:
in
Natural Science for his contributions to the field of
143:
and in 1957 he became a medical school professor at the
230:
49:, also known as Luria-Bertani medium or Lennox Broth.
256:
MacWilliams, Maria; Liao, Min-Ken (October 9, 2006).
151:. In the late 1950's/early 1960's he transferred to
420:
375:"Host Controlled Variation in Bacterial Viruses"
255:
131:. After his research group moved their lab to
372:
182:
38:, and spent most of his career working with
179:. Bertani passed away on April 7th, 2015.
99:. In 1948 he came to the US to work under
449:University of Southern California faculty
398:
373:Bertani, Giuseppe; Weigle, J. J. (1953).
310:
284:
227:Phages led him to develop the LB medium.
203:. Through this network he eventually met
186:
421:
61:on October 23rd 1923 but grew up in
352:10.1016/j.freeradbiomed.2014.07.010
231:Discovery of host control variation
13:
52:
14:
460:
366:
340:Free Radical Biology and Medicine
327:
265:American Society for Microbiology
211:. He was provided with lysogenic
145:University of Southern California
77:. He did a zoology fellowship in
81:for two years before heading to
16:Microbial geneticist (1923–2015)
285:Lindqvist, B H (May 27, 2015).
287:"Giuseppe Bertani (1923–2015)"
278:
249:
139:to continue his research with
1:
303:10.1080/21597081.2015.1054060
242:
105:Cold Spring Harbor Laboratory
57:Giuseppe Bertani was born in
391:10.1128/jb.65.2.113-121.1953
111:. Here he was introduced to
7:
69:. In 1945 he was awarded a
10:
465:
444:University of Milan alumni
159:. He also taught advanced
119:to microbial genetics and
115:and shifted his work from
42:, specifically phage P2.
183:Creation of the LB Medium
169:Jet Propulsion Laboratory
429:Italian microbiologists
379:Journal of Bacteriology
165:University of Stockholm
117:Drosophila melanogaster
92:Drosophila melanogaster
25:Drosophila melanogaster
217:Lisbonne strain and a
192:
190:
177:methanogenic bacteria
123:. In 1949 he went to
173:Pasadena, California
153:Karolinska Institute
83:Zurich, Switzerland
67:University of Milan
201:microbial genetics
193:
175:. Here he studied
125:Indiana University
113:microbial genetics
456:
413:
412:
402:
370:
364:
363:
331:
325:
324:
314:
282:
276:
275:
273:
271:
262:
253:
197:Milislav Demeric
101:Milislav Demerec
45:Bertani created
20:Giuseppe Bertani
464:
463:
459:
458:
457:
455:
454:
453:
419:
418:
417:
416:
371:
367:
332:
328:
297:(2): e1054060.
283:
279:
269:
267:
260:
254:
250:
245:
233:
185:
163:courses at the
109:Long Island N.Y
55:
53:Life and career
17:
12:
11:
5:
462:
452:
451:
446:
441:
436:
431:
415:
414:
385:(2): 113–121.
365:
326:
277:
247:
246:
244:
241:
237:Salvador Luria
232:
229:
205:Salvador Luria
191:Lysogeny Broth
184:
181:
85:to do further
54:
51:
47:Lysogeny broth
30:mutation rates
15:
9:
6:
4:
3:
2:
461:
450:
447:
445:
442:
440:
437:
435:
432:
430:
427:
426:
424:
410:
406:
401:
396:
392:
388:
384:
380:
376:
369:
361:
357:
353:
349:
345:
341:
337:
330:
322:
318:
313:
308:
304:
300:
296:
292:
291:Bacteriophage
288:
281:
266:
259:
252:
248:
240:
238:
228:
226:
222:
221:
216:
215:
210:
206:
202:
198:
189:
180:
178:
174:
170:
166:
162:
158:
154:
150:
146:
142:
138:
134:
130:
126:
122:
118:
114:
110:
106:
102:
98:
94:
93:
88:
84:
80:
79:Naples, Italy
76:
72:
68:
64:
60:
50:
48:
43:
41:
37:
36:
31:
27:
26:
21:
382:
378:
368:
343:
339:
329:
294:
290:
280:
270:February 15,
268:. Retrieved
264:
251:
234:
224:
218:
212:
194:
161:microbiology
141:Max Delbruch
116:
97:Ernst Hadorn
90:
56:
44:
33:
23:
19:
18:
439:2015 deaths
434:1923 births
346:: 245–251.
149:Los Angeles
59:Como, Italy
423:Categories
243:References
360:0891-5849
225:E. coli's
409:13034700
321:26442191
220:Shigella
209:lysogeny
133:Illinois
129:lysogeny
71:Laureate
312:4588218
214:E. coli
137:Caltech
103:at the
87:genetic
75:Zoology
35:E. coli
407:
400:169650
397:
358:
319:
309:
157:Sweden
121:phages
40:phages
261:(PDF)
147:, in
95:with
63:Milan
405:PMID
356:ISSN
317:PMID
272:2024
395:PMC
387:doi
348:doi
307:PMC
299:doi
171:in
155:in
107:in
32:in
425::
403:.
393:.
383:65
381:.
377:.
354:.
344:74
342:.
338:.
315:.
305:.
293:.
289:.
263:.
28:,
411:.
389::
362:.
350::
323:.
301::
295:5
274:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.