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Dinkel, Holger; Michael
Sushama; Weatheritt Robert J; Davey Norman E; Van Roey Kim; Altenberg Brigitte; Toedt Grischa; Uyar Bora; Seiler Markus; Budd Aidan; Jödicke Lisa; Dammert Marcel A; Schroeter Christian; Hammer Maria; Schmidt Tobias; Jehl Peter; McGuigan Caroline; Dymecka Magdalena; Chica
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rules. These expressions are used in the ELM prediction pipeline which detects putative motif instances in protein sequences. To improve the predictive power, context-based rules and logical filters are being developed and applied to reduce the amount of
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As of 2010 ELM contained 146 different motifs that annotate more than 1300 experimentally determined instances within proteins. The current version of the ELM server provides filtering by cell compartment, phylogeny, globular domain clash (using the
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Claudia; Luck Katja; Via
Allegra; Chatr-Aryamontri Andrew; Haslam Niall; Grebnev Gleb; Edwards Richard J; Steinmetz Michel O; Meiselbach Heike; Diella Francesca; Gibson Toby J (Jan 2012).
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databases) and structure. In addition, both the known ELM instances and any positionally conserved matches in sequences similar to ELM instance sequences are identified and displayed.
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240:"ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins"
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122:. It is currently the largest collection of linear motif classes with
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Via A, Gould CM, GemĂĽnd C, Gibson TJ, Helmer-Citterich M (2009).
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292:"ELM: the status of the 2010 eukaryotic linear motif resource"
341:"A structure filter for the Eukaryotic Linear Motif Resource"
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Puntervoll P, Linding R, GemĂĽnd C, et al. (July 2003).
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Gould CM, Diella F, Via A, et al. (January 2010).
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and experimentally validated linear motif instances.
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191:"ELM--the database of eukaryotic linear motifs"
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109:European Molecular Biology Laboratory
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129:Linear motifs are specified as
105:computational biology resource
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302:(Database issue): D167–80.
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111:(EMBL)) for investigating
420:Protein structural motifs
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39:eukaryotic linear motifs.
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358:10.1186/1471-2105-10-351
64:Dinkel & al. (2012)
101:Eukaryotic Linear Motif
195:Nucleic Acids Research
103:(ELM) resource is a
308:10.1093/nar/gkp1016
207:10.1093/nar/gkr1064
113:short linear motifs
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345:BMC Bioinformatics
256:10.1093/nar/gkg545
135:regular expression
107:(developed at the
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410:Protein databases
296:Nucleic Acids Res
244:Nucleic Acids Res
201:(D1): D242–D251.
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61:Primary citation
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250:(13): 3625–30.
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169:Minimotif miner
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140:false positives
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69:Release date
164:Phospho.ELM
115:(SLiMs) in
55:Toby Gibson
36:Description
404:Categories
175:References
117:eukaryotic
396:home page
142:matches.
124:annotated
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326:19920119
274:12824381
225:22110040
158:See also
131:patterns
120:proteins
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351:: 351.
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216:3245074
82:Website
49:Authors
44:Contact
31:Content
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133:using
77:Access
148:SMART
373:PMID
322:PMID
270:PMID
221:PMID
152:Pfam
99:The
91:.org
72:2011
394:ELM
363:PMC
353:doi
312:PMC
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89:.eu
87:elm
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