Knowledge

Dermatitis

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employed in healthcare and social assistance industries and life, physical, and social science occupations had the highest rates of reported dermatitis. About 6% of dermatitis cases among U.S. workers were attributed to work by a healthcare professional, indicating that the prevalence rate of work-related dermatitis among workers was at least 0.6%.
576:. It is supported by epidemiologic studies for asthma. The hypothesis states that exposure to bacteria and other immune system modulators is important during development, and missing out on this exposure increases the risk for asthma and allergy. One systematic review of literature on eczema found that 386:
Although the symptoms of atopic dermatitis vary from person to person, the most common symptoms are dry, itchy, red skin, on light skin. However, this redness does not appear on darker skin and dermatitis can appear darker brown or purple in color. Typical affected skin areas include the folds of the
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Dermatitis was estimated to affect 245 million people globally in 2015, or 3.34% of the world population. Atopic dermatitis is the most common type and generally starts in childhood. In the United States, it affects about 10–30% of people. Contact dermatitis is twice as common in females as in males.
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may be better in the short term and appear equal to steroids after a year of use. Their use is reasonable in those who do not respond to or are not tolerant of steroids. Treatments are typically recommended for short or fixed periods of time rather than indefinitely. Tacrolimus 0.1% has generally
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Dermatitis affected about 10% of U.S. workers in 2010, representing over 15 million workers with dermatitis. Prevalence rates were higher among females than among males and among those with some college education or a college degree compared to those with a high school diploma or less. Workers
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or breastfeeding affects the risk, nor is there evidence that delayed introduction of certain foods is useful. There is tentative evidence that probiotics in infancy may reduce rates but it is insufficient to recommend its use. There is moderate certainty evidence that the use of skin care
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Although little data on the rates of eczema over time exists prior to the 1940s, the rate of eczema has been found to have increased substantially in the latter half of the 20th century, with eczema in school-aged children being found to increase between the late 1940s and 2000. In the
849:. About three-quarters of cases of contact eczema are of the irritant type, which is the most common occupational skin disease. Contact eczema is curable, provided the offending substance can be avoided and its traces removed from one's environment. (ICD-10 L23; L24; L56.1; L56.0) 1055:
interventions such as emollients within the first year of life of an infant's life is not effective in preventing eczema. In fact, it may increase the risk of skin infection and of unwanted effects such as allergic reaction to certain moisturizers and a stinging sensation.
916:(nummular eczema, exudative eczema, microbial eczema) is characterized by round spots of oozing or dry rash, with clear boundaries, often on lower legs. It is usually worse in winter. The cause is unknown, and the condition tends to come and go. (ICD-10 L30.0) 245:. The type of dermatitis is generally determined by the person's history and the location of the rash. For example, irritant dermatitis often occurs on the hands of those who frequently get them wet. Allergic contact dermatitis occurs upon exposure to an 1448:
spinal manipulation lacks evidence to support its use for dermatitis. There is little evidence supporting the use of psychological treatments. While dilute bleach baths have been used for infected dermatitis there is little evidence for this practice.
3420:"The Effects of Early Nutritional Interventions on the Development of Atopic Disease in Infants and Children: The Role of Maternal Dietary Restriction, Breastfeeding, Hydrolyzed Formulas, and Timing of Introduction of Allergenic Complementary Foods" 304:(also known as atopic eczema). Terminology might also differ according to countries. In some languages, dermatitis and eczema mean the same thing, while in other languages dermatitis implies an acute condition and eczema a chronic one. 3218:
Johansson SG, Hourihane JO, Bousquet J, Bruijnzeel-Koomen C, Dreborg S, Haahtela T, et al. (September 2001). "A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force".
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and as a result are unable to keep foreign invaders out, leading to recurring infections. If left untreated, these infections may be life-threatening, so skin barrier improvement (such as daily moisturizing to minimize
535:, a potentially severe and sometimes fatal complication. Other major health risks for people with dermatitis are viral and bacterial infections because atopic dermatitis patients have deficiencies in their proteins and 3654:
Søyland E, Funk J, Rajka G, Sandberg M, Thune P, Rustad L, et al. (June 1994). "Dietary supplementation with very long-chain n-3 fatty acids in patients with atopic dermatitis. A double-blind, multicentre study".
336:. Dermatitis symptoms vary with all different forms of the condition. Although every type of dermatitis has different symptoms, there are certain signs that are common for all of them, including redness of the skin, 1012:. It is completely curable with the clearance of the original infection that caused it. The appearance varies depending on the cause. It always occurs some distance away from the original infection. (ICD-10 L30.2) 5852: 5833: 1513:, with female predominance of eczema presentations occurring during the reproductive period of 15–49 years. In the UK about 20% of children have the condition, while in the United States about 10% are affected. 1073:
may have a reduction in symptoms if eggs are eliminated from their diets. Benefits have not been shown for other elimination diets, though the studies are small and poorly executed. Establishing that there is a
714:(EAACI) published a position paper in 2001, which simplifies the nomenclature of allergy-related diseases, including atopic and allergic contact eczemas. Non-allergic eczemas are not affected by this proposal. 417:
are commonly present. The small red bumps experienced in this type of dermatitis are usually about 1 cm in size, red in color and may be found symmetrically grouped or distributed on the upper or lower back,
1197:) may reduce eczema severity and lead to fewer flares. In children, oil–based formulations appear to be better, and water–based formulations are not recommended. It is unclear if moisturizers that contain 1145:
There is no known cure for some types of dermatitis, with treatment aiming to control symptoms by reducing inflammation and relieving itching. Contact dermatitis is treated by avoiding what is causing it.
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Allergic contact dermatitis affects about 7% of people at some point in their lives. Irritant contact dermatitis is common, especially among people with certain occupations; exact rates are unclear.
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proved more effective than pimecrolimus, and equal in effect to mid-potency topical steroids. There is no association to increased risk of cancer from topical use of pimecrolimus nor tacrolimus.
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Le P, Tu J, Gebauer K, Brown S (May 2016). "Serum 25-hydroxyvitamin D increases with NB-UVB and UVA/UVB phototherapy in patients with psoriasis and atopic dermatitis in Western Australia".
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Hyperkeratotic hand dermatitis presents with hyperkeratotic, fissure-prone, erythematous areas of the middle or proximal palm, and the volar surfaces of the fingers may also be involved.
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Eczemas originating from ingestion of medications, foods, and chemicals, have not yet been clearly systematized. Other rare eczematous disorders exist in addition to those listed here.
1284:, may be useful in those who are unable to sleep due to eczema. Second generation antihistamines have minimal evidence of benefit. Of the second generation antihistamines studied, 344:
and skin lesions with sometimes oozing and scarring. Also, the area of the skin on which the symptoms appear tends to be different with every type of dermatitis, whether on the
1421:, balneophototherapy, psoralen plus UVA (PUVA), light has tentative support but the quality of the evidence is not very good compared with narrowband UVB, and UVA1. However, 4643: 1133:
developed essential fatty acid deficiency which was characterized by an increased food intake, poor growth, and a scaly dermatitis, and was cured by the administration of
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Snast I, Reiter O, Hodak E, Friedland R, Mimouni D, Leshem YA (April 2018). "Are Biologics Efficacious in Atopic Dermatitis? A Systematic Review and Meta-Analysis".
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Callaway J, Schwab U, Harvima I, Halonen P, Mykkänen O, Hyvönen P, et al. (April 2005). "Efficacy of dietary hempseed oil in patients with atopic dermatitis".
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Most cases are well managed with topical treatments and ultraviolet light. About 2% of cases are not. In more than 60% of young children, the condition subsides by
1249:) may be used. In severe cases, oral or injectable corticosteroids may be used. While these usually bring about rapid improvements, they have greater side effects. 1241:
are effective in controlling and suppressing symptoms in most cases. Once daily use is generally enough. For mild-moderate eczema a weak steroid may be used (e.g.,
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is particularly noticeable on the head and scalp, neck, inside of elbows, behind knees, and buttocks. It is very common in developed countries and rising. Irritant
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is a new medication that improves eczema lesions, especially moderate to severe eczema. Dupilumab, a monoclonal antibody, suppresses inflammation by targeting the
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refers to a set of clinical characteristics. Classification of the underlying diseases has been haphazard with numerous different classification systems, and many
711: 5305:"Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010" 732:, superficial dermatitis (in the epidermis, papillary dermis, and superficial vascular plexus) can basically be classified into either of the following groups: 2609: 935:, and is particularly common in the ankle area of people over 50. There is redness, scaling, darkening of the skin, and itching. The disorder predisposes to 752:
Without epidermal changes. These characteristically have a superficial perivascular inflammatory infiltrate and can be classified by type of cell infiltrate:
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Some cosmetics are marketed as hypoallergenic to imply that their use is less likely to lead to an allergic reaction than other products. However, the term
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there has been rise in the rate of eczema over time. The incidence and lifetime prevalence of eczema in England has been seen to increase in recent times.
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may reduce irritation in occupational irritant hand dermatitis, a skin disease that can affect people in jobs that regularly come into contact with water,
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areas have an increased prevalence of eczema compared to rural areas. While it has been suggested that eczema may sometimes be an allergic reaction to the
2469: 864:. It causes dry or greasy peeling of the scalp, eyebrows, and face, and sometimes trunk. In newborns, it causes a thick, yellow, crusty scalp rash called 6449: 2023:
Vos T, Allen C, Arora M, Barber RM, Bhutta ZA, Brown A, et al. (GBD 2015 Disease and Injury Incidence and Prevalence Collaborators) (October 2016).
905:, thickening, and cracks are accompanied by itching, which gets worse at night. A common type of hand eczema, it worsens in warm weather. (ICD-10 L30.1) 901:(dyshidrotic eczema, pompholyx, vesicular palmoplantar dermatitis) only occurs on palms, soles, and sides of fingers and toes. Tiny opaque bumps called 3804: 4613: 1961: 5567: 845:
Some substances act both as allergen and irritants (wet cement, for example). Other substances cause a problem after sunlight exposure, bringing on
1268:, where the skin turns red upon stopping steroid use, has been reported among adults who use topical steroids at least daily for more than a year. 2155:
Mowad CM, Anderson B, Scheinman P, Pootongkam S, Nedorost S, Brod B (June 2016). "Allergic contact dermatitis: Patient management and education".
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Torley D, Futamura M, Williams HC, Thomas KS (July 2013). "What's new in atopic eczema? An analysis of systematic reviews published in 2010–11".
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Taylor B, Wadsworth J, Wadsworth M, Peckham C (December 1984). "Changes in the reported prevalence of childhood eczema since the 1939–45 war".
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creams. The steroid creams should generally be of mid-to high strength and used for less than two weeks at a time, as side effects can occur.
5703: 3461:"Guidance for substantiating the evidence for beneficial effects of probiotics: prevention and management of allergic diseases by probiotics" 2283: 4552:"Cancer risk with topical calcineurin inhibitors, pimecrolimus and tacrolimus, for atopic dermatitis: a systematic review and meta-analysis" 1509:
Globally dermatitis affected approximately 230 million people as of 2010 (3.5% of the population). Dermatitis is most commonly seen in
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Gambichler T, Breuckmann F, Boms S, Altmeyer P, Kreuter A (April 2005). "Narrowband UVB phototherapy in skin conditions beyond psoriasis".
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Ciacci C, Cavallaro R, Iovino P, Sabbatini F, Palumbo A, Amoruso D, et al. (June 2004). "Allergy prevalence in adult celiac disease".
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are sometimes used. Immunosuppressants can cause significant side effects and some require regular blood tests. The most commonly used are
4718:"Incyte Announces U.S. FDA Approval of Opzelura (ruxolitinib) Cream, a Topical JAK Inhibitor, for the Treatment of Atopic Dermatitis (AD)" 4482: 3888: 3322: 950:(Duhring's disease) causes an intensely itchy and typically symmetrical rash on arms, thighs, knees, and back. It is directly related to 2250: 2133: 981:
rubbing and scratching. Usually, there is only one spot. Often curable through behaviour modification and anti-inflammatory medication.
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There has not been adequate evaluation of changing the diet to reduce eczema. There is some evidence that infants with an established
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Johansen JD, Hald M, Andersen BL, Laurberg G, Danielsen A, Avnstorp C, et al. (Danish Contact Dermatitis Group) (2011).
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of infants during at least the first few months may decrease the risk. There is no good evidence that a mother's diet during
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There have been various studies on the prevention of dermatitis through diet, none of which have proven any positive effect.
2443: 6284: 379:. Symptoms of this type of dermatitis may be very intense and may come and go. Irritant contact dermatitis is usually more 1865:
Ferri's Differential Diagnosis: A Practical Guide to the Differential Diagnosis of Symptoms, Signs, and Clinical Disorders
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reduction and avoidance measures have been studied in low quality trials and have not shown evidence of improving eczema.
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Although the location may vary, the primary symptom of this condition is itchy skin. More rarely, it may appear on the
4551: 5082: 3400: 588:, with up to 5% of people showing antibodies to the mites, the overall role this plays awaits further corroboration. 2613: 572:, eczema, and other allergic diseases is an unusually clean environment in childhood which leads to an insufficient 5615: 3834:
Ricci G, Patrizi A, Bellini F, Medri M (2006). "Use of textiles in atopic dermatitis: care of atopic dermatitis".
1173: 596: 1467:: it is unclear whether Chinese herbs help or harm. Dietary supplements are commonly used by people with eczema. 6158: 6116: 5949: 1690:
released a document about claims made concerning cosmetics, but this was issued as guidance, not a regulation.
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Makrgeorgou A, Leonardi-Bee J, Bath-Hextall FJ, Murrell DF, Tang ML, Roberts A, et al. (November 2018).
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are more or less effective than others. Products that contain dyes, perfumes, or peanuts should not be used.
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is an allergic disease believed to have a hereditary component and often runs in families whose members have
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The cause of dermatitis is unknown but is presumed to be a combination of genetic and environmental factors.
3812: 2751: 954:, can often be put into remission with an appropriate diet, and tends to get worse at night. (ICD-10 L13.0) 860:
or seborrheic dermatitis is a condition sometimes classified as a form of eczema that is closely related to
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are under preliminary research to determine their potential as treatments for atopic dermatitis, with only
1683: 1374: 5495:"Prevalence of dermatitis in the working population, United States, 2010 National Health Interview Survey" 6391: 6196: 6036: 6032: 4665:
Sawangjit R, Dilokthornsakul P, Lloyd-Lavery A, Lai NM, Dellavalle R, Chaiyakunapruk N (September 2020).
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Borda LJ, Perper M, Keri JE (March 2019). "Treatment of seborrheic dermatitis: a comprehensive review".
977:, localized scratch dermatitis) is an itchy area of thickened, pigmented eczema patch that results from 630:
and about two times more frequently in relatives of those with celiac disease, potentially indicating a
6404: 6143: 6098: 3305: 2950:"Celiac disease and dermatologic manifestations: many skin clue to unfold gluten-sensitive enteropathy" 2901:"Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis" 927:(gravitational eczema, stasis dermatitis, varicose eczema) occurs in people with impaired circulation, 454: 226:. The area of skin involved can vary from small to covering the entire body. Dermatitis is also called 4248: 4177:"Expert consensus: time for a change in the way we advise our patients to use topical corticosteroids" 902: 511: 4225: 1832: 1172:
should be avoided, as they tend to strip the skin of natural oils and lead to excessive dryness. The
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Carswell F, Thompson S (July 1986). "Does natural sensitisation in eczema occur through the skin?".
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If symptoms are well controlled with moisturizers, steroids may only be required when flares occur.
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Kelleher MM, Phillips R, Brown SJ, Cro S, Cornelius V, Carlsen KC, et al. (14 November 2022).
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Paternoster L, Standl M, Chen CM, Ramasamy A, Bønnelykke K, Duijts L, et al. (December 2011).
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Luckhaupt SE, Dahlhamer JM, Ward BW, Sussell AL, Sweeney MH, Sestito JP, et al. (June 2013).
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Apfelbacher CJ, van Zuuren EJ, Fedorowicz Z, Jupiter A, Matterne U, Weisshaar E (February 2013).
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Bamford JT, Ray S, Musekiwa A, van Gool C, Humphreys R, Ernst E (April 2013). Bamford JT (ed.).
4910: 1461:: There is currently no scientific evidence for the claim that sulfur treatment relieves eczema. 16:
This article is about eczema and dermatitis in general. For the most common type of eczema, see
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Bath-Hextall FJ, Jenkinson C, Humphreys R, Williams HC (February 2012). Bath-Hextall FJ (ed.).
5106:"The treatment of eczema with Chinese herbs: a systematic review of randomized clinical trials" 4550:
Devasenapathy N, Chu A, Wong M, Srivastava A, Ceccacci R, Lin C, et al. (1 January 2023).
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Nankervis H, Pynn EV, Boyle RJ, Rushton L, Williams HC, Hewson DM, et al. (January 2015).
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or other irritants. Some emollients may reduce the number of flares in people with dermatitis.
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suggests using a controlled amount of bleach diluted in a bath to help with atopic dermatitis.
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Ersser SJ, Cowdell F, Latter S, Gardiner E, Flohr C, Thompson AR, et al. (January 2014).
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Bauer A, Rönsch H, Elsner P, Dittmar D, Bennett C, Schuttelaar ML, et al. (April 2018).
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Johansson SG, Bieber T, Dahl R, Friedmann PS, Lanier BQ, Lockey RF, et al. (May 2004).
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are sometimes used synonymously. However the term eczema is often used to specifically mean
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Lauffer F, Ring J (2016). "Target-oriented therapy: Emerging drugs for atopic dermatitis".
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Lurati AR (February 2015). "Occupational risk assessment and irritant contact dermatitis".
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Vos T, Flaxman AD, Naghavi M, Lozano R, Michaud C, Ezzati M, et al. (December 2012).
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Bathing once or more a day is recommended, usually for five to ten minutes in warm water.
8: 6434: 6381: 6374: 6191: 5989: 5856: 2610:"CDC Smallpox | Smallpox (Vaccinia) Vaccine Contraindications (Info for Clinicians)" 2569: 1698: 913: 400: 5704:"EU 'free from' cosmetics claims technical document is guidance, not regulation: Expert" 5354:"Gender-specific presentations for asthma, allergic rhinitis and eczema in primary care" 4817:
Gambichler T (March 2009). "Management of atopic dermatitis using photo(chemo)therapy".
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Matterne U, Böhmer MM, Weisshaar E, Jupiter A, Carter B, Apfelbacher CJ (January 2019).
3624: 3568: 3034: 441:, on the other hand, tend to appear gradually, from dry or greasy scaling of the scalp ( 6337: 6296: 6088: 6027: 5796: 5753: 5658: 5470: 5445: 5426: 5378: 5353: 5329: 5280: 5255: 5231: 5206: 5179: 5154: 5130: 5105: 5057: 5003: 4978: 4954: 4937: 4891: 4842: 4799: 4691: 4666: 4587: 4532: 4423: 4398: 4379: 4350:"What's new in atopic eczema? An analysis of systematic reviews published in 2009-2010" 4325: 4300: 4273: 4206: 4145: 4092: 4079: 4029: 3975: 3923: 3723: 3680: 3668: 3593: 3537: 3504: 3374: 3283: 3258: 3193: 2976: 2949: 2925: 2900: 2837: 2787: 2664: 2639: 2387: 2336: 2215: 2049: 2024: 2002: 1616:
as a topical treatment for eczema was fashionable in the Victorian and Edwardian eras.
1377:(FDA) for the topical treatment of mild to moderate atopic dermatitis. It is a topical 1221: 1202: 993: 978: 819: 804: 615:
A number of genes have been associated with eczema, one of which affects production of
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is the only one to show evidence of improvement in itching with minimal side effects.
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The exact cause of the condition is often unclear. Cases may involve a combination of
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van Zuuren EJ, Fedorowicz Z, Christensen R, Lavrijsen A, Arents BW (February 2017).
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Murphy LA, White IR, Rastogi SC (May 2004). "Is hypoallergenic a credible term?".
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Kalliomäki M, Antoine JM, Herz U, Rijkers GT, Wells JM, Mercenier A (March 2010).
3362: 2752:"Is there a rural/urban gradient in the prevalence of eczema? A systematic review" 6444: 6418: 6386: 6352: 6342: 6291: 6267: 6262: 6201: 6083: 5883: 5676: 5551: 3781: 3764: 2439: 1518: 1475: 1320:
When eczema is severe and does not respond to other forms of treatment, systemic
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People can wear clothing designed to manage the itching, scratching and peeling.
996:(id reaction, auto sensitization) is an eczematous reaction to an infection with 970: 696: 643: 600: 585: 223: 5446:"Trends in the epidemiology and prescribing of medication for eczema in England" 5078: 3567:
Bath-Hextall F, Delamere FM, Williams HC (January 2008). Bath-Hextall FJ (ed.).
2168: 453:, the condition causes a thick and yellowish scalp rash, often accompanied by a 276:. Contact dermatitis is typically treated by avoiding the allergen or irritant. 6332: 6272: 6216: 5921: 4752: 3622: 3012: 2655: 2093: 2076: 1687: 1654: 1261: 1242: 951: 928: 835: 729: 663: 627: 540: 273: 230:
but the same term is often used for the most common type of skin inflammation,
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is not regulated, and no research has been done showing that products labeled
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Overexposure to ultraviolet light carries its own risks, particularly that of
6428: 6179: 6128: 6093: 6058: 5994: 5935: 5461: 4575: 3528: 2882: 2775: 2203: 1536: 1277: 1213: 1118: 1114: 1094: 1047: 695:), by specific appearance (eczema craquele or discoid) or by possible cause ( 312: 277: 242: 183: 5846: 5842: 5613: 5369: 4301:"Oral H1 antihistamines as 'add-on' therapy to topical treatment for eczema" 3274: 3165: 2311:(2nd ed.). Berlin, Heidelberg: Springer Berlin Heidelberg. p. 42. 1086:
Oils with fatty acids that have been studied to prevent dermatitis include:
475: 6257: 5792: 5749: 5654: 5518: 5479: 5387: 5338: 5289: 5240: 5188: 5139: 5053: 5012: 4979:"Psychological and educational interventions for atopic eczema in children" 4963: 4887: 4838: 4795: 4760: 4700: 4583: 4528: 4432: 4375: 4334: 4282: 4202: 4154: 4088: 4025: 3984: 3932: 3913: 3873: 3790: 3719: 3602: 3546: 3505:"Skin care interventions in infants for preventing eczema and food allergy" 3486: 3445: 3436: 3419: 3370: 3292: 3240: 3217: 3189: 3077: 3020: 2985: 2934: 2868: 2783: 2708: 2673: 2383: 2211: 2176: 2102: 2058: 1998: 1445: 1418: 1414: 1333: 1329: 1309: 1285: 1280:
medications for the relief of dermatitis. Sedative antihistamines, such as
1253: 1130: 1075: 1064: 936: 659: 368: 175: 5422: 5253: 4862:"Phototherapy in the management of atopic dermatitis: a systematic review" 3676: 3477: 3460: 2966: 2833: 2750:
Schram M, Tedja A, Spijker R, Bos J, Williams H, Spuls P (16 March 2010).
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are less problematic than any others. In 1977, courts overruled the U.S.
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Osman M, Hansell AL, Simpson CR, Hollowell J, Helms PJ (February 2007).
3948: 3855: 1728:
for moderate-to-severe atopic dermatitis in 2017 and for asthma in 2018.
838:), and irritant (resulting from direct reaction to a detergent, such as 6369: 6133: 6017: 5510: 4664: 1485: 1478:
taken orally have been shown to be effective. Both are associated with
1398: 1354: 1313: 1194: 1153: 882: 877: 865: 827: 669: 577: 462: 269: 203: 5825: 5152: 5044: 5027: 4787: 4520: 4246: 4016: 3999: 3889:"House dust mite reduction and avoidance measures for treating eczema" 3847: 1989: 1980: 6301: 5913: 4938:"Treatment of acute atopic eczema by chiropractic care. A case study" 2887: 1721: 1702: 1339: 1217: 1051: 616: 581: 446: 147: 5494: 4136: 4118: 4052:"Interventions for preventing occupational irritant hand dermatitis" 2916: 2687:
Bufford JD, Gern JE (May 2005). "The hygiene hypothesis revisited".
985:
is a related disorder showing multiple lumps. (ICD-10 L28.0; L28.1)
626:
Eczema occurs about three times more frequently in individuals with
6226: 6174: 4639: 2947: 1198: 1134: 1100: 1090: 1029: 1005: 997: 861: 823: 822:
is of two types: allergic (resulting from a delayed reaction to an
631: 450: 442: 427: 419: 246: 211: 82: 1686:'s regulation of the use of the term hypoallergenic. In 2019, the 1425:
is more effective than UVA1 for treatment of atopical dermatitis.
445:) to scaling of facial areas, sometimes with itching, but without 6235: 5614:
Center for Food Safety and Applied Nutrition (1 September 2020).
5028:"Use of bleach baths for the treatment of infected atopic eczema" 3056:
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before dietary change could avoid unnecessary lifestyle changes.
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James WD, Elston D, Treat JR, Rosenbach MA, Neuhaus I (2019).
1245:), while in more severe cases a higher-potency steroid (e.g., 699:). Further adding to the confusion, many sources use the term 5492: 2898: 2638:
Wang V, Boguniewicz J, Boguniewicz M, Ong PY (January 2021).
2637: 1661: 1644: 1637: 1631: 1624: 1589: 1582: 1576: 1569: 1561: 1554: 1546: 1539: 1257: 1009: 1001: 932: 885:
such as anti-dandruff shampoo can be helpful in treating it.
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symptoms include itching, stinging and a burning sensation.
6230: 4976: 1296: 1169: 800: 396: 392: 388: 380: 345: 341: 215: 207: 78: 5204: 672:
are used in the diagnosis of allergic contact dermatitis.
5727: 4667:"Systemic treatments for eczema: a network meta-analysis" 3886: 3762: 3090: 2268:. In Barker J, Bleiker TO, Chalmers R, Creamer D (eds.). 1893: 1833:"Handout on Health: Atopic Dermatitis (A type of eczema)" 1600: 1422: 1401: 1193:
Low-quality evidence indicates that moisturizing agents (
691:
A type of dermatitis may be described by location (e.g.,
4049: 3833: 3653: 3502: 1962:"Management of difficult and severe eczema in childhood" 1028:), and eczemas resulting from underlying disease (e.g., 875:
There is a connection between seborrheic dermatitis and
5302: 5081:. University of Maryland Medical Center. 1 April 2002. 3631:. Institute for Quality and Efficiency in Health Care. 1488:
are likely to make little to no difference in symptoms.
712:
European Academy of Allergology and Clinical Immunology
280:
may help with sleep and decrease nighttime scratching.
4116: 3391:
James, William; Berger, Timothy; Elston, Dirk (2005).
6402: 5207:"Oral evening primrose oil and borage oil for eczema" 4911:"Psoriasis PUVA Treatment Can Increase Melanoma Risk" 4866:
Photodermatology, Photoimmunology & Photomedicine
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Institute for Quality and Efficiency in Health Care.
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associated with eczema: OVOL1, ACTL9 and IL4-KIF3A.
5155:"Dietary supplements for established atopic eczema" 4119:"Systematic review of treatments for atopic eczema" 3393:
Andrews' Diseases of the Skin: Clinical Dermatology
2640:"The infectious complications of atopic dermatitis" 2022: 1897:
Andrews' Diseases of the Skin: Clinical Dermatology
5632: 4707: 4249:"Oral H1 antihistamines as monotherapy for eczema" 3618: 3616: 3569:"Dietary exclusions for established atopic eczema" 3562: 3560: 3558: 3556: 3417: 3136:(6th ed.). Hamilton, Ontario: BC Decker Inc. 2633: 2631: 1959: 1129:In the 1950s Arild Hansen showed that infants fed 539:that have barrier functions along with defects in 256:Prevention of atopic dermatitis is typically with 4348:Shams K, Grindlay DJ, Williams HC (August 2011). 2398: 717: 218:. In cases of short duration, there may be small 6426: 5146: 4773: 3765:"Soak and smear: a standard technique revisited" 3625:"Eczema: Can eliminating particular foods help?" 2811: 2493:"Eczema in skin of color: What you need to know" 1252:Long term use of topical steroids may result in 1020:There are eczemas overlaid by viral infections ( 807:is sometimes misdiagnosed as atopic dermatitis. 599:results in a dermatitis similar to that seen in 320:There are several types of dermatitis including 5556:. Taylor & Francis. 1 May 2008. p. 1. 4481:. US Food and Drug Administration. March 2014. 3997: 3613: 3553: 3348: 3256: 3129: 3091:Johansen JD, Frosch PJ, Lepoittevin JP (2010). 2689:Immunology and Allergy Clinics of North America 2628: 1276:There is little evidence supporting the use of 658:. Those with eczema may be especially prone to 222:, while in long-term cases the skin may become 193:245 million in 2015 (3.34% of world population) 5200: 5198: 5103: 4741:Journal of the American Academy of Dermatology 3418:Greer FR, Sicherer SH, Burks AW (April 2019). 3001:The Journal of Allergy and Clinical Immunology 2263: 2157:Journal of the American Academy of Dermatology 2081:The Journal of Allergy and Clinical Immunology 5957: 5296: 4449:. NHS Choices, London, UK. 12 February 2016. 4045: 4043: 3252: 3250: 2341:ICD-11 for Mortality and Morbidity Statistics 505:A patch of dermatitis that has been scratched 403:refers to a red bumpy rash around the mouth. 5626: 5025: 4935: 4110: 3211: 2848: 2588: 2236:Middleton's Allergy: Principles and Practice 2018: 2016: 1960:McAleer MA, Flohr C, Irvine AD (July 2012). 5770: 5260:The Cochrane Database of Systematic Reviews 5211:The Cochrane Database of Systematic Reviews 5195: 5159:The Cochrane Database of Systematic Reviews 4983:The Cochrane Database of Systematic Reviews 4671:The Cochrane Database of Systematic Reviews 4305:The Cochrane Database of Systematic Reviews 4294: 4292: 4253:The Cochrane Database of Systematic Reviews 4059:The Cochrane Database of Systematic Reviews 3955:The Cochrane Database of Systematic Reviews 3893:The Cochrane Database of Systematic Reviews 3573:The Cochrane Database of Systematic Reviews 3509:The Cochrane Database of Systematic Reviews 3385: 2805: 2686: 1775:Generalized Dermatitis in Clinical Practice 1612:was coined in 1933 by Wise and Sulzberger. 688:being used to describe the same condition. 642:Diagnosis of eczema is based mostly on the 6450:Steroid-responsive inflammatory conditions 5964: 5950: 5486: 5073: 5071: 4942:Australasian Chiropractic & Osteopathy 4816: 4040: 3413: 3411: 3409: 3344: 3342: 3340: 3311: 3247: 2960:. Hindawi Publishing Corporation: 952753. 2644:Annals of Allergy, Asthma & Immunology 2355: 1827: 1767: 1765: 1705:showing evidence of efficacy, as of 2018. 872:and is often curable. (ICD-10 L21; L21.0) 703:interchangeably for the most common type: 527:People with eczema should not receive the 56:A moderate case of dermatitis of the hands 47: 5971: 5469: 5377: 5328: 5279: 5230: 5178: 5129: 5043: 5002: 4953: 4877: 4690: 4636:"Dupixent- dupilumab injection, solution" 4422: 4365: 4324: 4272: 4192: 4144: 4117:Hoare C, Li Wan Po A, Williams H (2000). 4078: 4015: 3974: 3922: 3912: 3780: 3592: 3536: 3476: 3435: 3282: 2975: 2965: 2924: 2663: 2092: 2048: 2013: 1988: 1955: 1953: 1951: 1949: 1947: 1945: 1943: 1941: 1939: 1937: 1900:. 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Genome-wide studies found three new 272:may be required if there are signs of 202:is a term used for different types of 5945: 5635:Clinical and Experimental Dermatology 5592:from the original on 22 February 2016 5104:Armstrong NC, Ernst E (August 1999). 4509:Clinical and Experimental Dermatology 4488:from the original on 11 February 2017 4465: 4354:Clinical and Experimental Dermatology 3609:from the original on 21 October 2013. 3498: 3496: 3039:University of Maryland Medical Center 2857:Annales Academiae Medicae Stetinensis 2115: 1914: 1861: 1291: 988: 307: 6285:Hydroxyethyl starch-induced pruritus 4453:from the original on 16 January 2017 4396: 3635:from the original on 21 October 2013 2730:The Lecturio Medical Concept Library 2715: 2576:from the original on 2 February 2017 2550:from the original on 2 February 2017 2524:from the original on 2 February 2017 2446:from the original on 2 February 2017 2325:from the original on 16 August 2016. 2253:from the original on 15 August 2016. 2070: 2068: 1373:(Opzelura) was approved by the U.S. 888: 6049:Urushiol-induced contact dermatitis 5604: 4819:Archives of Dermatological Research 4236:from the original on 16 March 2016. 4226:"Topical corticosteroid withdrawal" 3939: 3838:. Current Problems in Dermatology. 3321:. Dermnetnz.org. 28 December 2013. 2572:. DermNet New Zealand Trust. 2017. 2546:. DermNet New Zealand Trust. 2017. 2520:. DermNet New Zealand Trust. 2017. 2442:. DermNet New Zealand Trust. 2017. 2286:from the original on 15 August 2016 2136:from the original on 17 August 2016 1792:from the original on 15 August 2016 1411:in persons in individuals with AD. 13: 6122:Autoimmune progesterone dermatitis 5938:. American Academy of Dermatology. 5085:from the original on 5 August 2012 4646:from the original on 24 March 2021 4616:from the original on 28 March 2017 4223: 4181:The British Journal of Dermatology 3669:10.1111/j.1365-2133.1994.tb03414.x 3657:The British Journal of Dermatology 3493: 3045:from the original on 27 July 2016. 2440:"Neurodermatitis (lichen simplex)" 1232: 965: 14: 6461: 5811: 5570:from the original on 28 May 2016. 4000:"Eczema and ceramides: an update" 3325:from the original on 5 March 2014 2598:. Merck Manual, Consumer Version. 2472:from the original on 16 June 2010 2065: 1389: 1271: 957: 868:, which seems related to lack of 742:Non vesiculobullous, non-pustular 675: 6412: 5773:Expert Opinion on Emerging Drugs 5764: 5695: 5669: 5647:10.1111/j.1365-2230.2004.01521.x 5358:Primary Care Respiratory Journal 5256:"Probiotics for treating eczema" 5122:10.1046/j.1365-2125.1999.00004.x 4879:10.1111/j.1600-0781.2007.00291.x 4367:10.1111/j.1365-2230.2011.04078.x 4194:10.1111/j.1365-2133.2008.08479.x 3319:"Balsam of Peru contact allergy" 3182:10.1111/j.1600-0536.2011.01911.x 3130:Rietschel RL, Fowler JF (2008). 3111:from the original on 5 July 2014 2768:10.1111/j.1365-2133.2010.09689.x 1843:from the original on 30 May 2015 1384: 942: 559: 522: 510: 498: 486: 474: 23:Inflammatory disease of the skin 5702:Kulliney K (6 September 2019). 5574: 5544: 5525: 5437: 5394: 5345: 5247: 5097: 5019: 4970: 4929: 4902: 4853: 4810: 4767: 4732: 4658: 4628: 4598: 4543: 4439: 4341: 4240: 4168: 3880: 3827: 3797: 3756: 3742:"Coping with atopic dermatitis" 3734: 3691: 3647: 3299: 3157: 3123: 3084: 3049: 3027: 2992: 2941: 2892: 2875: 2743: 2680: 2602: 2562: 2536: 2510: 2484: 2458: 2432: 2329: 2298: 2257: 2226: 2183: 1715: 1504: 1188: 1174:American Academy of Dermatology 1058: 782: 597:Essential fatty acid deficiency 591: 6159:Hyperkeratotic hand dermatitis 6117:Autoimmune estrogen dermatitis 5272:10.1002/14651858.CD006135.pub3 5223:10.1002/14651858.CD004416.pub2 5171:10.1002/14651858.CD005205.pub3 4995:10.1002/14651858.CD004054.pub3 4683:10.1002/14651858.cd013206.pub2 4317:10.1002/14651858.CD012167.pub2 4265:10.1002/14651858.CD007770.pub2 4071:10.1002/14651858.CD004414.pub3 3967:10.1002/14651858.CD012119.pub2 3905:10.1002/14651858.CD008426.pub2 3585:10.1002/14651858.CD005203.pub2 3521:10.1002/14651858.CD013534.pub3 2756:British Journal of Dermatology 2308:Textbook of Contact Dermatitis 2270:Rook's Textbook of Dermatology 2148: 2109: 1855: 1724:received approval from the US 1452: 1349: 1227: 1081: 893: 852: 718:Histopathologic classification 287: 1: 6368:substances taken internally: 6207:Nutritional deficiency eczema 6013:Pityriasis simplex capillitii 5785:10.1517/14728214.2016.1146681 5553:Textbook of Atopic Dermatitis 5415:10.1016/S0140-6736(84)92805-8 5321:10.1016/S0140-6736(12)61729-2 4568:10.1016/S2352-4642(22)00283-8 4232:. DermNet New Zealand Trust. 3363:10.1080/09546634.2018.1473554 3263:Journal of Clinical Pathology 2826:10.1016/S0140-6736(86)92560-2 2491:Hewett L (2 September 2022). 2266:"Allergic Contact Dermatitis" 2264:Wilkinson M, Orton D (2016). 2192:Workplace Health & Safety 2041:10.1016/S0140-6736(16)31678-6 1735: 1357:are used in the treatment of 1140: 1038: 634:link between the conditions. 568:postulates that the cause of 6166:Autosensitization dermatitis 6054:African blackwood dermatitis 5616:""Hypoallergenic" Cosmetics" 5540:. Tufts University: Perseus. 4610:Food and Drug Administration 4360:(6): 573–577, quiz 577–578. 4124:Health Technology Assessment 3782:10.1001/archderm.141.12.1556 3308:National Eczema Association. 2726:"Atopic Dermatitis (Eczema)" 2370:(9): ITC51–15, quiz ITC516. 1726:Food and Drug Administration 1684:Food and Drug Administration 1662: 1645: 1632: 1590: 1577: 1562: 1547: 1492: 1375:Food and Drug Administration 1163: 637: 7: 6392:Papuloerythroderma of Ofuji 6197:Juvenile plantar dermatosis 4909:Stöppler MC (31 May 2007). 4720:. Incyte. 21 September 2021 4447:"Atopic eczema - Treatment" 3133:Fisher's Contact Dermatitis 2497:National Eczema Association 2364:Annals of Internal Medicine 2169:10.1016/j.jaad.2015.02.1144 1693: 114:irritant contact dermatitis 110:allergic contact dermatitis 10: 6466: 6144:Topical steroid withdrawal 6099:Protein contact dermatitis 5708:cosmeticsdesign-europe.com 4753:10.1016/j.jaad.2004.08.047 4728:– via Business Wire. 4612:(FDA). 10 September 2019. 3013:10.1016/j.jaci.2004.03.012 2656:10.1016/j.anai.2020.08.002 2544:"Dermatitis herpetiformis" 2518:"Periorificial dermatitis" 2094:10.1016/j.jaci.2003.12.591 1638: 1625: 1583: 1570: 1555: 1540: 1440: 1062: 908: 814: 721: 610: 531:due to risk of developing 465:, around the nose, on the 260:, and may be treated with 15: 6361: 6225: 6212:Sulzberger–Garbe syndrome 6107: 6026: 6003: 5980: 5893: 5819: 5742:10.1007/s40257-017-0324-7 4831:10.1007/s00403-008-0923-5 4415:10.1007/s40272-013-0013-9 3712:10.1080/09546630510035832 3070:10.1016/j.pop.2007.09.003 2701:10.1016/j.iac.2005.03.005 2411:. Birkhäuser. p. 4. 2408:Handbook of atopic eczema 1658: 1397:(AD) may be treated with 1364: 919: 787: 759:Lymphocytic (most common) 546:transepidermal water loss 469:, and on the upper back. 189: 171: 161: 137: 127: 101: 89: 72: 60: 55: 46: 38: 33: 6244:Lichen simplex chronicus 5462:10.1258/jrsm.2009.080211 3465:The Journal of Nutrition 3395:. (10th ed.). Saunders. 2204:10.1177/2165079914565351 1708: 1205:at night may be useful. 1015: 975:lichen simplex chronicus 948:Dermatitis herpetiformis 551: 407:Dermatitis herpetiformis 156:lichen simplex chronicus 152:dermatitis herpetiformis 6069:Abietic acid dermatitis 5586:www.merriam-webster.com 5538:A Greek-English Lexicon 5370:10.3132/pcrj.2007.00006 4397:Carr WW (August 2013). 3769:Archives of Dermatology 3275:10.1136/jcp.2005.027151 2596:"Seborrheic Dermatitis" 2570:"Seborrheic dermatitis" 2337:"Dermatitis and eczema" 736:Vesiculobullous lesions 461:, on the bridge of the 5936:Eczema Resource Center 5582:"Definition of ECZEMA" 3629:Informed Health Online 3437:10.1542/peds.2019-0281 1596: 1480:gastrointestinal upset 1379:Janus kinase inhibitor 1344:interleukin-4 receptor 1301: 1156:such as anti-dandruff 858:Seborrhoeic dermatitis 749:With epidermal changes 650:. In uncertain cases, 493:More severe dermatitis 439:seborrhoeic dermatitis 387:arms, the back of the 334:seborrhoeic dermatitis 317: 316:Dermatitis of the hand 253:reaction in the skin. 139:Differential diagnosis 118:seborrhoeic dermatitis 6280:Drug-induced pruritus 6005:Seborrheic dermatitis 5683:. European Commission 5532:Liddell HG, Scott R. 4175:Bewley A (May 2008). 3478:10.3945/jn.109.113761 2468:. Mayo Clinic. 2015. 2198:(2): 81–87, quiz 88. 1699:Monoclonal antibodies 1533: 1529:Etymology and history 1359:seborrheic dermatitis 1299: 1247:clobetasol propionate 1150:Seborrheic dermatitis 1105:Eicosapentaenoic acid 847:phototoxic dermatitis 840:sodium lauryl sulfate 315: 258:essential fatty acids 166:Essential fatty acids 6326:Cholestatic pruritus 6316:due to liver disease 6185:Molluscum dermatitis 2695:(2): 247–262, v–vi. 2233:Adkinson NF (2014). 2119:Clinical Dermatology 2035:(10053): 1545–1602. 1772:Nedorost ST (2012). 1472:evening primrose oil 1436:Alternative medicine 1123:alpha-Linolenic acid 1109:docosahexaenoic acid 648:physical examination 529:smallpox vaccination 6440:Autoimmune diseases 6382:Nummular dermatitis 6375:Fixed drug reaction 6192:Circumostomy eczema 5990:Prurigo gestationis 5409:(8414): 1255–1257. 5315:(9859): 2163–2196. 3064:(1): 119–140, vii. 2967:10.1155/2012/952753 1670:Society and culture 1649:'inflammation' and 1406:25-hydroxyvitamin D 1369:In September 2021, 1203:Occlusive dressings 739:Pustular dermatosis 654:may be taken for a 401:Perioral dermatitis 6338:Prurigo pigmentosa 6297:Aquagenic pruritus 6089:Contact stomatitis 6028:Contact dermatitis 5894:External resources 5511:10.1002/ajim.22080 4004:Contact Dermatitis 3170:Contact Dermatitis 3094:Contact Dermatitis 2616:on 25 January 2010 2305:Frosch PJ (2013). 1623:is from the Greek 1404:, which increases 1322:immunosuppressants 1306:immunosuppressants 1302: 1292:Immunosuppressants 994:Autoeczematization 989:Autoeczematization 820:Contact dermatitis 805:contact dermatitis 762:Lymphoeosinophilic 566:hygiene hypothesis 517:Complex dermatitis 326:contact dermatitis 318: 308:Signs and symptoms 243:poor venous return 6400: 6399: 6311:Adult blaschkitis 6248:Prurigo nodularis 6139:Eyelid dermatitis 6079:Airbag dermatitis 5982:Atopic dermatitis 5931: 5930: 5563:978-0-203-09144-9 5045:10.1111/ajd.12015 4788:10.1111/ajd.12315 4521:10.1111/ced.12143 4017:10.1111/cod.12073 3865:978-3-8055-8121-9 3848:10.1159/000093940 3775:(12): 1556–1559. 3306:Atopic Dermatitis 3269:(12): 1233–1241. 3143:978-1-55009-378-0 3104:978-3-642-03827-3 2883:Atopic Dermatitis 2466:"Neurodermatitis" 2418:978-3-540-23133-2 2318:978-3-662-03104-9 2279:978-1-118-44117-6 2246:978-0-323-08593-9 2129:978-0-323-26607-9 2116:Habif TP (2015). 1981:10.1136/bmj.e4770 1907:978-0-323-55188-5 1875:978-0-323-07699-9 1862:Ferri FF (2010). 1785:978-1-4471-2897-7 1610:atopic dermatitis 1465:Chinese herbology 1395:Atopic dermatitis 1371:ruxolitinib cream 1022:eczema herpeticum 983:Prurigo nodularis 939:. (ICD-10 I83.1) 889:Less common types 793:Atopic dermatitis 771:Lymphohistiocytic 765:Lymphoplasmacytic 705:atopic dermatitis 605:biotin deficiency 533:eczema vaccinatum 330:stasis dermatitis 322:atopic dermatitis 302:atopic dermatitis 232:atopic dermatitis 197: 196: 129:Diagnostic method 122:stasis dermatitis 106:Atopic dermatitis 28:Medical condition 18:Atopic dermatitis 6457: 6417: 6416: 6415: 6408: 6348:Puncta pruritica 6321:Biliary pruritus 5966: 5959: 5952: 5943: 5942: 5817: 5816: 5805: 5804: 5768: 5762: 5761: 5725: 5719: 5718: 5716: 5714: 5699: 5693: 5692: 5690: 5688: 5673: 5667: 5666: 5630: 5624: 5623: 5611: 5602: 5601: 5599: 5597: 5578: 5572: 5571: 5548: 5542: 5541: 5529: 5523: 5522: 5490: 5484: 5483: 5473: 5441: 5435: 5434: 5398: 5392: 5391: 5381: 5349: 5343: 5342: 5332: 5300: 5294: 5293: 5283: 5266:(11): CD006135. 5251: 5245: 5244: 5234: 5202: 5193: 5192: 5182: 5150: 5144: 5143: 5133: 5101: 5095: 5094: 5092: 5090: 5075: 5066: 5065: 5047: 5023: 5017: 5016: 5006: 4974: 4968: 4967: 4957: 4933: 4927: 4926: 4924: 4922: 4906: 4900: 4899: 4881: 4857: 4851: 4850: 4814: 4808: 4807: 4771: 4765: 4764: 4736: 4730: 4729: 4727: 4725: 4714: 4705: 4704: 4694: 4662: 4656: 4655: 4653: 4651: 4642:. 25 June 2020. 4632: 4626: 4625: 4623: 4621: 4602: 4596: 4595: 4547: 4541: 4540: 4504: 4498: 4497: 4495: 4493: 4487: 4480: 4472: 4463: 4462: 4460: 4458: 4443: 4437: 4436: 4426: 4403:Paediatric Drugs 4394: 4388: 4387: 4369: 4345: 4339: 4338: 4328: 4296: 4287: 4286: 4276: 4244: 4238: 4237: 4221: 4215: 4214: 4196: 4172: 4166: 4165: 4163: 4161: 4148: 4114: 4108: 4107: 4105: 4103: 4097: 4091:. Archived from 4082: 4056: 4047: 4038: 4037: 4019: 3995: 3989: 3988: 3978: 3946: 3937: 3936: 3926: 3916: 3884: 3878: 3877: 3831: 3825: 3824: 3822: 3820: 3811:. Archived from 3801: 3795: 3794: 3784: 3760: 3754: 3753: 3751: 3749: 3738: 3732: 3731: 3695: 3689: 3688: 3651: 3645: 3644: 3642: 3640: 3620: 3611: 3610: 3596: 3564: 3551: 3550: 3540: 3515:(11): CD013534. 3500: 3491: 3490: 3480: 3471:(3): 713S–721S. 3456: 3450: 3449: 3439: 3430:(4): e20190281. 3415: 3404: 3389: 3383: 3382: 3346: 3335: 3334: 3332: 3330: 3315: 3309: 3303: 3297: 3296: 3286: 3254: 3245: 3244: 3215: 3209: 3208: 3206: 3204: 3161: 3155: 3154: 3152: 3150: 3127: 3121: 3120: 3118: 3116: 3088: 3082: 3081: 3053: 3047: 3046: 3031: 3025: 3024: 3007:(6): 1199–1203. 2996: 2990: 2989: 2979: 2969: 2945: 2939: 2938: 2928: 2896: 2890: 2879: 2873: 2872: 2852: 2846: 2845: 2809: 2803: 2802: 2800: 2798: 2747: 2741: 2740: 2738: 2736: 2722: 2713: 2712: 2684: 2678: 2677: 2667: 2635: 2626: 2625: 2623: 2621: 2606: 2600: 2599: 2592: 2586: 2585: 2583: 2581: 2566: 2560: 2559: 2557: 2555: 2540: 2534: 2533: 2531: 2529: 2514: 2508: 2507: 2505: 2503: 2488: 2482: 2481: 2479: 2477: 2462: 2456: 2455: 2453: 2451: 2436: 2430: 2429: 2427: 2425: 2402: 2396: 2395: 2359: 2353: 2352: 2350: 2348: 2333: 2327: 2326: 2302: 2296: 2295: 2293: 2291: 2261: 2255: 2254: 2230: 2224: 2223: 2187: 2181: 2180: 2163:(6): 1043–1054. 2152: 2146: 2145: 2143: 2141: 2113: 2107: 2106: 2096: 2072: 2063: 2062: 2052: 2020: 2011: 2010: 1992: 1966: 1957: 1912: 1911: 1891: 1880: 1879: 1859: 1853: 1852: 1850: 1848: 1829: 1802: 1801: 1799: 1797: 1769: 1729: 1719: 1665: 1660: 1648: 1643: 1642: 1641: 1635: 1630: 1629: 1628: 1604: 1593: 1588: 1587: 1586: 1580: 1575: 1574: 1573: 1565: 1560: 1559: 1558: 1550: 1545: 1544: 1543: 1266:Red burning skin 1152:is treated with 842:, for example). 621:genetic variants 586:house dust mites 574:human microbiota 514: 502: 490: 478: 437:The symptoms of 251:hypersensitivity 133:Based on symptom 51: 31: 30: 6465: 6464: 6460: 6459: 6458: 6456: 6455: 6454: 6425: 6424: 6423: 6413: 6411: 6403: 6401: 6396: 6387:Pityriasis alba 6357: 6353:Uremic pruritus 6343:Prurigo simplex 6292:Senile pruritus 6268:Pruritus vulvae 6263:Pruritus scroti 6234: 6221: 6202:Nummular eczema 6103: 6084:Baboon syndrome 6030: 6022: 5999: 5976: 5970: 5932: 5927: 5926: 5889: 5888: 5828: 5814: 5809: 5808: 5769: 5765: 5726: 5722: 5712: 5710: 5700: 5696: 5686: 5684: 5675: 5674: 5670: 5631: 5627: 5612: 5605: 5595: 5593: 5580: 5579: 5575: 5564: 5550: 5549: 5545: 5530: 5526: 5491: 5487: 5442: 5438: 5399: 5395: 5350: 5346: 5301: 5297: 5252: 5248: 5217:(4): CD004416. 5203: 5196: 5165:(2): CD005205. 5151: 5147: 5102: 5098: 5088: 5086: 5077: 5076: 5069: 5024: 5020: 4989:(1): CD004054. 4975: 4971: 4934: 4930: 4920: 4918: 4913:. MedicineNet. 4907: 4903: 4858: 4854: 4815: 4811: 4772: 4768: 4737: 4733: 4723: 4721: 4716: 4715: 4708: 4677:(9): CD013206. 4663: 4659: 4649: 4647: 4634: 4633: 4629: 4619: 4617: 4604: 4603: 4599: 4548: 4544: 4505: 4501: 4491: 4489: 4485: 4478: 4474: 4473: 4466: 4456: 4454: 4445: 4444: 4440: 4395: 4391: 4346: 4342: 4311:(1): CD012167. 4297: 4290: 4259:(2): CD007770. 4245: 4241: 4222: 4218: 4173: 4169: 4159: 4157: 4137:10.3310/hta4370 4115: 4111: 4101: 4099: 4098:on 6 March 2020 4095: 4065:(4): CD004414. 4054: 4048: 4041: 3996: 3992: 3961:(8): CD012119. 3947: 3940: 3899:(5): CD008426. 3885: 3881: 3866: 3832: 3828: 3818: 3816: 3815:on 29 July 2020 3803: 3802: 3798: 3761: 3757: 3747: 3745: 3740: 3739: 3735: 3696: 3692: 3652: 3648: 3638: 3636: 3621: 3614: 3579:(1): CD005203. 3565: 3554: 3501: 3494: 3457: 3453: 3416: 3407: 3390: 3386: 3347: 3338: 3328: 3326: 3317: 3316: 3312: 3304: 3300: 3255: 3248: 3216: 3212: 3202: 3200: 3162: 3158: 3148: 3146: 3144: 3128: 3124: 3114: 3112: 3105: 3089: 3085: 3054: 3050: 3033: 3032: 3028: 2997: 2993: 2946: 2942: 2917:10.1038/ng.1017 2905:Nature Genetics 2897: 2893: 2880: 2876: 2853: 2849: 2820:(8497): 13–15. 2810: 2806: 2796: 2794: 2748: 2744: 2734: 2732: 2724: 2723: 2716: 2685: 2681: 2636: 2629: 2619: 2617: 2608: 2607: 2603: 2594: 2593: 2589: 2579: 2577: 2568: 2567: 2563: 2553: 2551: 2542: 2541: 2537: 2527: 2525: 2516: 2515: 2511: 2501: 2499: 2489: 2485: 2475: 2473: 2464: 2463: 2459: 2449: 2447: 2438: 2437: 2433: 2423: 2421: 2419: 2403: 2399: 2360: 2356: 2346: 2344: 2335: 2334: 2330: 2319: 2303: 2299: 2289: 2287: 2280: 2262: 2258: 2247: 2231: 2227: 2188: 2184: 2153: 2149: 2139: 2137: 2130: 2114: 2110: 2073: 2066: 2021: 2014: 1964: 1958: 1915: 1908: 1892: 1883: 1876: 1860: 1856: 1846: 1844: 1831: 1830: 1805: 1795: 1793: 1786: 1770: 1743: 1738: 1733: 1732: 1720: 1716: 1711: 1696: 1672: 1639: 1626: 1606: 1598: 1584: 1571: 1567: 1556: 1552: 1541: 1531: 1519:developed world 1507: 1495: 1476:borage seed oil 1455: 1443: 1438: 1409: 1392: 1387: 1367: 1352: 1300:Tacrolimus 0.1% 1294: 1282:diphenhydramine 1274: 1239:Corticosteroids 1235: 1233:Corticosteroids 1230: 1191: 1183:House dust mite 1166: 1143: 1084: 1067: 1061: 1041: 1018: 991: 971:Neurodermatitis 968: 966:Neurodermatitis 960: 945: 922: 911: 896: 891: 855: 817: 790: 785: 726: 720: 697:varicose eczema 678: 640: 613: 594: 562: 554: 541:dendritic cells 525: 518: 515: 506: 503: 494: 491: 482: 479: 426:, knees, neck, 310: 290: 29: 24: 21: 12: 11: 5: 6463: 6453: 6452: 6447: 6442: 6437: 6422: 6421: 6398: 6397: 6395: 6394: 6389: 6384: 6378: 6377: 6372: 6365: 6363: 6359: 6358: 6356: 6355: 6350: 6345: 6340: 6335: 6333:Prion pruritus 6330: 6329: 6328: 6323: 6313: 6307: 6306: 6305: 6304: 6294: 6289: 6288: 6287: 6276: 6275: 6273:Scalp pruritus 6270: 6265: 6260: 6251: 6250: 6240: 6238: 6223: 6222: 6220: 6219: 6217:Xerotic eczema 6214: 6209: 6204: 6199: 6194: 6189: 6188: 6187: 6182: 6177: 6163: 6162: 6161: 6156: 6146: 6141: 6136: 6131: 6125: 6124: 6119: 6113: 6111: 6105: 6104: 6102: 6101: 6096: 6091: 6086: 6081: 6076: 6071: 6062: 6061: 6056: 6051: 6042: 6040: 6024: 6023: 6021: 6020: 6015: 6009: 6007: 6001: 6000: 5998: 5997: 5992: 5986: 5984: 5978: 5977: 5969: 5968: 5961: 5954: 5946: 5940: 5939: 5929: 5928: 5925: 5924: 5910: 5898: 5897: 5895: 5891: 5890: 5887: 5886: 5875: 5864: 5849: 5829: 5824: 5823: 5821: 5820:Classification 5813: 5812:External links 5810: 5807: 5806: 5763: 5736:(2): 145–165. 5720: 5694: 5668: 5625: 5603: 5573: 5562: 5543: 5524: 5505:(6): 625–634. 5485: 5456:(3): 108–117. 5436: 5393: 5344: 5295: 5246: 5194: 5145: 5116:(2): 262–264. 5096: 5067: 5038:(4): 251–258. 5018: 4969: 4928: 4901: 4872:(4): 106–112. 4852: 4825:(3): 197–203. 4809: 4782:(2): 115–121. 4766: 4747:(4): 660–670. 4731: 4706: 4657: 4627: 4597: 4542: 4515:(5): 449–456. 4499: 4464: 4438: 4409:(4): 303–310. 4389: 4340: 4288: 4239: 4216: 4187:(5): 917–920. 4167: 4109: 4039: 3990: 3938: 3879: 3864: 3842:(3): 127–143. 3826: 3796: 3755: 3733: 3690: 3663:(6): 757–764. 3646: 3612: 3552: 3492: 3451: 3405: 3384: 3357:(2): 158–169. 3336: 3310: 3298: 3246: 3227:(9): 813–824. 3210: 3156: 3142: 3122: 3103: 3083: 3048: 3026: 2991: 2940: 2911:(2): 187–192. 2891: 2874: 2863:(2): 123–127. 2847: 2804: 2762:(5): 964–973. 2742: 2714: 2679: 2627: 2601: 2587: 2561: 2535: 2509: 2483: 2457: 2431: 2417: 2397: 2354: 2328: 2317: 2297: 2278: 2256: 2245: 2225: 2182: 2147: 2128: 2108: 2087:(5): 832–836. 2064: 2012: 1913: 1906: 1881: 1874: 1854: 1803: 1784: 1740: 1739: 1737: 1734: 1731: 1730: 1713: 1712: 1710: 1707: 1695: 1692: 1688:European Union 1680:hypoallergenic 1676:hypoallergenic 1671: 1668: 1532: 1530: 1527: 1506: 1503: 1494: 1491: 1490: 1489: 1483: 1468: 1462: 1454: 1451: 1442: 1439: 1437: 1434: 1407: 1391: 1390:Narrowband UVB 1388: 1386: 1383: 1366: 1363: 1351: 1348: 1293: 1290: 1273: 1272:Antihistamines 1270: 1262:telangiectasia 1243:hydrocortisone 1234: 1231: 1229: 1226: 1214:barrier creams 1190: 1187: 1165: 1162: 1142: 1139: 1127: 1126: 1112: 1098: 1083: 1080: 1060: 1057: 1040: 1037: 1017: 1014: 990: 987: 967: 964: 959: 958:Hyperkeratotic 956: 952:celiac disease 944: 941: 929:varicose veins 921: 918: 914:Discoid eczema 910: 907: 895: 892: 890: 887: 854: 851: 836:Balsam of Peru 816: 813: 789: 786: 784: 781: 780: 779: 778: 777: 776: 775: 772: 769: 766: 763: 760: 754: 753: 750: 744: 743: 740: 737: 730:histopathology 722:Main article: 719: 716: 677: 676:Classification 674: 664:food allergies 639: 636: 628:celiac disease 612: 609: 593: 590: 561: 558: 553: 550: 524: 521: 520: 519: 516: 509: 507: 504: 497: 495: 492: 485: 483: 480: 473: 371:, such as the 309: 306: 289: 286: 278:Antihistamines 274:skin infection 195: 194: 191: 187: 186: 184:antihistamines 173: 169: 168: 163: 159: 158: 141: 135: 134: 131: 125: 124: 103: 99: 98: 96:Skin infection 93: 87: 86: 76: 70: 69: 64: 58: 57: 53: 52: 44: 43: 40: 36: 35: 27: 22: 9: 6: 4: 3: 2: 6462: 6451: 6448: 6446: 6443: 6441: 6438: 6436: 6433: 6432: 6430: 6420: 6410: 6409: 6406: 6393: 6390: 6388: 6385: 6383: 6380: 6379: 6376: 6373: 6371: 6367: 6366: 6364: 6360: 6354: 6351: 6349: 6346: 6344: 6341: 6339: 6336: 6334: 6331: 6327: 6324: 6322: 6319: 6318: 6317: 6314: 6312: 6309: 6308: 6303: 6300: 6299: 6298: 6295: 6293: 6290: 6286: 6283: 6282: 6281: 6278: 6277: 6274: 6271: 6269: 6266: 6264: 6261: 6259: 6256: 6253: 6252: 6249: 6245: 6242: 6241: 6239: 6237: 6232: 6228: 6224: 6218: 6215: 6213: 6210: 6208: 6205: 6203: 6200: 6198: 6195: 6193: 6190: 6186: 6183: 6181: 6180:Dermatophytid 6178: 6176: 6173: 6172: 6171: 6167: 6164: 6160: 6157: 6155: 6152: 6151: 6150: 6147: 6145: 6142: 6140: 6137: 6135: 6132: 6130: 6129:Breast eczema 6127: 6126: 6123: 6120: 6118: 6115: 6114: 6112: 6110: 6106: 6100: 6097: 6095: 6094:Metal allergy 6092: 6090: 6087: 6085: 6082: 6080: 6077: 6075: 6072: 6070: 6067: 6064: 6063: 6060: 6059:Tulip fingers 6057: 6055: 6052: 6050: 6047: 6044: 6043: 6041: 6038: 6034: 6029: 6025: 6019: 6016: 6014: 6011: 6010: 6008: 6006: 6002: 5996: 5995:Sweat allergy 5993: 5991: 5988: 5987: 5985: 5983: 5979: 5974: 5967: 5962: 5960: 5955: 5953: 5948: 5947: 5944: 5937: 5934: 5933: 5923: 5920: 5916: 5915: 5911: 5909: 5905: 5904: 5900: 5899: 5896: 5892: 5885: 5881: 5880: 5876: 5874: 5870: 5869: 5865: 5863: 5859: 5858: 5854: 5850: 5848: 5844: 5840: 5839: 5835: 5831: 5830: 5827: 5822: 5818: 5802: 5798: 5794: 5790: 5786: 5782: 5778: 5774: 5767: 5759: 5755: 5751: 5747: 5743: 5739: 5735: 5731: 5724: 5709: 5705: 5698: 5682: 5678: 5672: 5664: 5660: 5656: 5652: 5648: 5644: 5640: 5636: 5629: 5621: 5617: 5610: 5608: 5591: 5587: 5583: 5577: 5569: 5565: 5559: 5555: 5554: 5547: 5539: 5535: 5528: 5520: 5516: 5512: 5508: 5504: 5500: 5496: 5489: 5481: 5477: 5472: 5467: 5463: 5459: 5455: 5451: 5447: 5440: 5432: 5428: 5424: 5420: 5416: 5412: 5408: 5404: 5397: 5389: 5385: 5380: 5375: 5371: 5367: 5363: 5359: 5355: 5348: 5340: 5336: 5331: 5326: 5322: 5318: 5314: 5310: 5306: 5299: 5291: 5287: 5282: 5277: 5273: 5269: 5265: 5261: 5257: 5250: 5242: 5238: 5233: 5228: 5224: 5220: 5216: 5212: 5208: 5201: 5199: 5190: 5186: 5181: 5176: 5172: 5168: 5164: 5160: 5156: 5149: 5141: 5137: 5132: 5127: 5123: 5119: 5115: 5111: 5107: 5100: 5084: 5080: 5074: 5072: 5063: 5059: 5055: 5051: 5046: 5041: 5037: 5033: 5029: 5022: 5014: 5010: 5005: 5000: 4996: 4992: 4988: 4984: 4980: 4973: 4965: 4961: 4956: 4951: 4948:(3): 96–101. 4947: 4943: 4939: 4932: 4916: 4912: 4905: 4897: 4893: 4889: 4885: 4880: 4875: 4871: 4867: 4863: 4856: 4848: 4844: 4840: 4836: 4832: 4828: 4824: 4820: 4813: 4805: 4801: 4797: 4793: 4789: 4785: 4781: 4777: 4770: 4762: 4758: 4754: 4750: 4746: 4742: 4735: 4719: 4713: 4711: 4702: 4698: 4693: 4688: 4684: 4680: 4676: 4672: 4668: 4661: 4645: 4641: 4637: 4631: 4615: 4611: 4607: 4601: 4593: 4589: 4585: 4581: 4577: 4573: 4569: 4565: 4561: 4557: 4553: 4546: 4538: 4534: 4530: 4526: 4522: 4518: 4514: 4510: 4503: 4484: 4477: 4471: 4469: 4452: 4448: 4442: 4434: 4430: 4425: 4420: 4416: 4412: 4408: 4404: 4400: 4393: 4385: 4381: 4377: 4373: 4368: 4363: 4359: 4355: 4351: 4344: 4336: 4332: 4327: 4322: 4318: 4314: 4310: 4306: 4302: 4295: 4293: 4284: 4280: 4275: 4270: 4266: 4262: 4258: 4254: 4250: 4243: 4235: 4231: 4227: 4220: 4212: 4208: 4204: 4200: 4195: 4190: 4186: 4182: 4178: 4171: 4156: 4152: 4147: 4142: 4138: 4134: 4131:(37): 1–191. 4130: 4126: 4125: 4120: 4113: 4094: 4090: 4086: 4081: 4076: 4072: 4068: 4064: 4060: 4053: 4046: 4044: 4035: 4031: 4027: 4023: 4018: 4013: 4009: 4005: 4001: 3994: 3986: 3982: 3977: 3972: 3968: 3964: 3960: 3956: 3952: 3945: 3943: 3934: 3930: 3925: 3920: 3915: 3914:10044/1/21547 3910: 3906: 3902: 3898: 3894: 3890: 3883: 3875: 3871: 3867: 3861: 3857: 3853: 3849: 3845: 3841: 3837: 3830: 3814: 3810: 3806: 3800: 3792: 3788: 3783: 3778: 3774: 3770: 3766: 3759: 3743: 3737: 3729: 3725: 3721: 3717: 3713: 3709: 3705: 3701: 3694: 3686: 3682: 3678: 3674: 3670: 3666: 3662: 3658: 3650: 3634: 3630: 3626: 3619: 3617: 3608: 3604: 3600: 3595: 3590: 3586: 3582: 3578: 3574: 3570: 3563: 3561: 3559: 3557: 3548: 3544: 3539: 3534: 3530: 3526: 3522: 3518: 3514: 3510: 3506: 3499: 3497: 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Retrieved 1774: 1717: 1697: 1679: 1675: 1673: 1666:'eruption'. 1650: 1620: 1618: 1609: 1607: 1597: 1534: 1523: 1515: 1508: 1505:Epidemiology 1496: 1446:Chiropractic 1444: 1427: 1419:heliotherapy 1413: 1393: 1368: 1353: 1338: 1334:methotrexate 1330:azathioprine 1319: 1310:pimecrolimus 1303: 1286:fexofenadine 1275: 1254:skin atrophy 1251: 1236: 1210:moisturizers 1207: 1192: 1189:Moisturizers 1181: 1178: 1167: 1148: 1144: 1131:skimmed milk 1128: 1085: 1076:food allergy 1068: 1065:Healthy diet 1059:Healthy diet 1045: 1042: 1034: 1019: 992: 969: 961: 946: 923: 912: 897: 881:fungus, and 876: 874: 856: 844: 818: 791: 783:Common types 774:Neutrophilic 727: 709: 700: 690: 681: 679: 668: 660:misdiagnosis 641: 625: 614: 595: 592:Malnutrition 563: 555: 526: 436: 405: 385: 383:than itchy. 369:genital area 366: 319: 297: 293: 291: 282: 262:moisturizers 255: 249:, causing a 236: 227: 199: 198: 176:Moisturizers 25: 6170:Id reaction 6154:Dyshidrosis 6149:Hand eczema 6074:Diaper rash 5903:MedlinePlus 5596:15 February 4160:18 November 3836:Respiration 3809:www.aad.org 2650:(1): 3–12. 2502:16 November 1636:'skin' and 1499:adolescence 1453:Supplements 1430:skin cancer 1355:Antifungals 1350:Antifungals 1326:ciclosporin 1228:Medications 1154:antifungals 1082:Fatty acids 1071:egg allergy 899:Dyshidrosis 894:Dyshidrosis 883:antifungals 853:Seborrhoeic 693:hand eczema 670:Patch tests 652:skin biopsy 455:diaper rash 288:Terminology 270:Antibiotics 67:Dermatology 39:Other names 6435:Dermatitis 6429:Categories 6370:Bromoderma 6134:Ear eczema 6018:Cradle cap 5975:and eczema 5973:Dermatitis 5713:7 December 5687:7 December 5089:15 October 4921:17 October 4492:27 January 4457:27 January 4230:DermNet NZ 4224:Oakley A. 3424:Pediatrics 2620:7 February 2580:29 January 2554:29 January 2528:29 January 2476:6 November 2450:29 January 1990:2262/75991 1736:References 1621:dermatitis 1594:'to boil' 1486:Probiotics 1399:narrowband 1314:tacrolimus 1218:detergents 1195:emollients 1141:Management 1121:(LA), and 1107:(EPA) and 1063:See also: 1046:Exclusive 1039:Prevention 1026:vaccinatum 937:leg ulcers 878:Malassezia 866:cradle cap 828:poison ivy 826:, such as 481:Dermatitis 391:, wrists, 294:dermatitis 292:The terms 200:Dermatitis 162:Prevention 34:Dermatitis 6302:Aquadynia 5914:eMedicine 5801:207484890 4592:253470127 4576:2352-4642 3529:1469-493X 2888:eMedicine 2792:205259960 2776:0007-0963 2392:207536375 2347:12 August 1975:: e4770. 1722:Dupilumab 1703:dupilumab 1619:The word 1608:The term 1493:Prognosis 1340:Dupilumab 1222:chemicals 1199:ceramides 1164:Lifestyle 1052:pregnancy 998:parasites 768:Mast cell 680:The term 638:Diagnosis 617:filaggrin 582:excrement 447:hair loss 428:shoulders 224:thickened 208:itchiness 190:Frequency 172:Treatment 148:psoriasis 79:Itchiness 62:Specialty 6419:Medicine 6227:Pruritus 6175:Candidid 6037:irritant 6033:allergic 5922:Ped/2567 5793:26808004 5750:29098604 5663:41482522 5655:15115531 5590:Archived 5568:Archived 5534:"Ekzema" 5519:22674651 5480:19297652 5388:17297524 5339:23245607 5290:30480774 5241:23633319 5189:22336810 5140:10417508 5083:Archived 5079:"Sulfur" 5062:19644659 5054:23330843 5013:24399641 4964:17987197 4915:Archived 4896:25684608 4888:17598862 4847:29045951 4839:19142651 4804:41245703 4796:25916422 4761:15793518 4701:32927498 4644:Archived 4640:DailyMed 4620:29 March 4614:Archived 4584:36370744 4537:24638685 4529:23750610 4483:Archived 4451:Archived 4433:23549982 4384:42321918 4376:21718344 4335:30666626 4283:23450580 4234:Archived 4211:46445371 4203:18294314 4155:11134919 4089:29708265 4026:23869725 3985:28166390 3933:25598014 3874:16766885 3791:16365257 3728:18445488 3720:16019622 3685:25066444 3633:Archived 3607:Archived 3603:18254073 3547:36373988 3487:20130079 3446:30886111 3379:13686180 3371:29737895 3323:Archived 3293:16311340 3241:11551246 3198:30780460 3190:21658054 3149:21 April 3115:21 April 3109:Archived 3078:18206721 3043:Archived 3035:"Eczema" 3021:15208605 2986:22693492 2935:22197932 2869:17633128 2842:23111491 2784:20331459 2709:15878454 2674:32771354 2574:Archived 2548:Archived 2522:Archived 2470:Archived 2444:Archived 2384:22041966 2323:Archived 2284:Archived 2251:Archived 2220:40077567 2212:25881659 2177:27185422 2134:Archived 2103:15131563 2059:27733282 2007:36038433 1999:22826585 1841:Archived 1790:Archived 1694:Research 1653:is from 1581:'out' + 1563:ekzé-ein 1557:ἐκζέ-ειν 1470:Neither 1304:Topical 1135:corn oil 1101:Fish oil 1091:Corn oil 1030:lymphoma 1006:bacteria 979:habitual 903:vesicles 862:dandruff 824:allergen 799:. Itchy 686:synonyms 459:eyebrows 451:newborns 443:dandruff 420:buttocks 415:vesicles 338:swelling 247:allergen 220:blisters 182:creams, 83:red skin 74:Symptoms 6236:Prurigo 6046:plants: 5919:Derm/38 5884:D004485 5758:4220890 5471:2746851 5431:2842761 5423:6150286 5379:6634172 5330:6350784 5281:6517242 5232:8105655 5180:6517242 5131:2014284 5004:6457897 4955:2051093 4692:8128359 4608:. 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Index

Atopic dermatitis

Specialty
Dermatology
Symptoms
Itchiness
red skin
Complications
Skin infection
Atopic dermatitis
allergic contact dermatitis
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seborrhoeic dermatitis
stasis dermatitis
Diagnostic method
Differential diagnosis
Scabies
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dermatitis herpetiformis
lichen simplex chronicus
Essential fatty acids
Moisturizers
steroid
antihistamines
skin
itchiness
redness
rash
blisters
thickened

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