1232:
333:
310:
232:
207:
2544:
584:
339:
238:
40:
2529:
1207:
of 4,224 nucleotides encodes the long isoform, CR1; this is predicted to be a protein of 1,408 amino acids that includes 21 short consensus repeats (SCR) of ca. 60 amino acids each, plus transmembrane and cytoplasmic regions. Isoform CR2 (1,032 amino acids) is encoded by a shorter transcript (3,096
1218:
Isoforms CR1 and CR2 derived from the non-primate Cr2 locus possess the same C-terminal sequence, such that association with and activation through CD19 should be equivalent. CR1 can bind to C4b and C3b complexes, whereas CR2 (murine and human) binds to C3dg-bound complexes. CR1, a surface protein
1202:
The canonical Cr2/CD21 gene of subprimate mammals produces two types of complement receptor (CR1, ca. 200 kDa; CR2, ca. 145 kDa) via alternative mRNA splicing. The murine Cr2 gene contains 25 exons; a common first exon is spliced to exon 2 and to exon 9 in transcripts encoding CR1 and CR2,
66:
2439:
Barel M, Balbo M, Gauffre A, Frade R (1995). "Binding sites of the
Epstein-Barr virus and C3d receptor (CR2, CD21) for its three intracellular ligands, the p53 anti-oncoprotein, the p68 calcium binding protein and the nuclear p120 ribonucleoprotein".
1527:
Yefenof E, Klein G, Jondal M, Oldstone MB (June 1976). "Surface markers on human B and T-lymphocytes. IX. Two-color immunofluorescence studies on the association between ebv receptors and complement receptors on the surface of lymphoid cell lines".
1247:. In more conventional paraffin-embedded tissue samples, only the FDCs retain the staining pattern. As a result, CR2, more commonly called CD21 in the context of immunohistochemistry, can be used to demonstrate the FDC meshwork in lymphoid tissue.
1208:
coding nucleotides) that lacks exons 2-8 encoding SCR1-6. CR1 and CR2 on murine B cells form complexes with a co-accessory activation complex containing CD19, CD81, and the fragilis/Ifitm (murine equivalents of LEU13) proteins.
346:
245:
2259:"Identification of a partial cDNA clone for the C3d/Epstein-Barr virus receptor of human B lymphocytes: homology with the receptor for fragments C3b and C4b of the third and fourth components of complement"
1215:, which recapitulates many of the structural domains and presumed functions of Cr2-derived CR1 in subprimates, is encoded by a distinct CR1 gene (apparently derived from the gene Crry of subprimates).
5490:
5048:
1835:"T lymphocyte expression of complement receptor 2 (CR2/CD21): a role in adhesive cell-cell interactions and dysregulation in a patient with systemic lupus erythematosus (SLE)"
5483:
3872:
1804:
Gauffre A, Viron A, Barel M, et al. (1992). "Nuclear localization of the
Epstein-Barr virus/C3d receptor (CR2) in the human Burkitt B lymphoma cell, Raji".
2543:
3011:
2093:"Murine complement receptor gene family. II. Identification and characterization of the murine homolog (Cr2) to human CR2 and its molecular linkage to Crry"
1223:, appears to be critical for generation of appropriately activated B cells of the germinal centre and for mature antibody responses to bacterial infection.
5476:
5041:
2216:"Structure of the human B lymphocyte receptor for C3d and the Epstein-Barr virus and relatedness to other members of the family of C3/C4 binding proteins"
842:
168:
823:
1878:"Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19"
1720:
5034:
2007:"Intracellular interaction of EBV/C3d receptor (CR2) with p68, a calcium-binding protein present in normal but not in transformed B lymphocytes"
1282:
is typified by the presence of abnormal FDCs, and both this, and malignant FDC tumours may therefore be demonstrated using CR2/CD21 antibodies.
3862:
5871:
2989:
1358:
1340:
5876:
1419:"The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules"
2584:
5957:
5952:
5884:
3842:
1052:
1671:"Divergent immunohistochemical expression of CD21 and CD23 by follicular dendritic cells with increasing grade of follicular lymphoma"
1622:"Optimal germinal center B cell activation and T-dependent antibody responses require expression of the mouse complement receptor Cr1"
1059:
6002:
5982:
5972:
5967:
5937:
4704:
3028:
3004:
1190:(EBV) can bind CR2, enabling EBV to enter and infect B cells. Yefenof et al. (1976) found complete overlapping of EBV receptors and
6045:
5924:
6012:
5352:
4435:
1403:
2171:"Molecular cloning of the cDNA encoding the Epstein-Barr virus/C3d receptor (complement receptor type 2) of human B lymphocytes"
5798:
4423:
4201:
4487:
4482:
4428:
4208:
2508:
1749:
1239:
Although CR2 is present on all mature B-cells and follicular dendritic cells (FDCs), this becomes readily apparent only when
1153:
express CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation.
1323:
6091:
3941:
3867:
2997:
63:
4970:
4965:
4960:
4955:
3882:
1302:
5468:
2798:
1921:"Molecular interactions of complement receptors on B lymphocytes: a CR1/CR2 complex distinct from the CR2/CD19 complex"
5616:
4935:
1515:
1387:
332:
5761:
4171:
4739:
4233:
3919:
2577:
1327:
1306:
309:
4378:
3914:
2617:
1231:
887:
3019:
2312:"A complement receptor locus: genes encoding C3b/C4b receptor and C3d/Epstein-Barr virus receptor map to 1q32"
5240:
4875:
4347:
4342:
4287:
4021:
3470:
1726:- This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (
868:
4569:
4292:
2607:
231:
206:
148:
2355:"CD23 interacts with a new functional extracytoplasmic domain involving N-linked oligosaccharides on CD21"
5913:
3887:
1173:(TAPA-1). The CR2-CD19-CD81 complex is often called the B cell co-receptor complex, because CR2 binds to
1162:
6096:
5503:
5057:
4599:
3024:
2570:
2528:
345:
244:
3465:
2853:
2501:
1378:
Frank K, Atkinson JP (2001). "Complement system." In Austen KF, Frank K, Atkinson JP, Cantor H. eds.
1220:
338:
237:
135:
4649:
3544:
2480:
1668:
1244:
1012:
986:
957:
156:
2476:
5449:
4613:
2933:
2803:
2768:
2763:
2658:
2653:
2648:
1016:
982:
961:
5430:
5207:
5197:
5120:
3956:
3951:
3946:
3936:
3243:
3171:
2823:
2813:
2808:
2758:
2737:
2682:
2665:
1279:
1235:
Patterns of CD21 (or CD23) expression by the follicular dendritic cells in follicular lymphoma.
1191:
5525:
5499:
3300:
2900:
2701:
1714:
1212:
139:, C3DR, CD21, CR, CVID7, SLEB9, complement component 3d receptor 2, complement C3d receptor 2
5587:
5554:
5577:
4537:
4250:
2915:
2910:
2494:
2270:
1267:
1240:
1184:
binds antigen. This results in the B cell having greatly enhanced response to the antigen.
220:
17:
8:
4564:
4383:
2892:
2872:
2862:
2711:
1669:
Kurshumliu F, Sadiku-Zehri F, Qerimi A, Vela Z, Jashari F, Bytyci S; et al. (2019).
1271:
176:
5498:
5026:
2274:
3971:
3705:
2422:
2397:
2384:
2341:
2240:
2215:
2122:
2065:
2036:
1993:
1945:
1920:
1902:
1877:
1859:
1850:
1834:
1697:
1670:
1646:
1621:
1597:
1572:
1553:
1448:
1204:
1187:
180:
2293:
2258:
2197:
2170:
2152:
2135:
2074:
2049:
757:
752:
747:
742:
737:
732:
727:
722:
717:
712:
707:
691:
686:
681:
676:
671:
655:
650:
645:
640:
635:
630:
625:
5903:
2593:
2457:
2453:
2427:
2376:
2333:
2298:
2245:
2202:
2157:
2136:"Genomic organization and polymorphisms of the human C3d/Epstein-Barr virus receptor"
2114:
2079:
2028:
1985:
1950:
1907:
1864:
1821:
1817:
1792:
1745:
1702:
1651:
1602:
1545:
1511:
1489:
1440:
1383:
1138:
128:
56:
2388:
2345:
2126:
2040:
1997:
1739:
1557:
1452:
5856:
5170:
4744:
4477:
4398:
3961:
3154:
3080:
2967:
2920:
2742:
2552:: Crystal structure of unliganded human CD21 SCR1-SCR2 (Complement receptor type 2)
2449:
2417:
2409:
2366:
2323:
2288:
2278:
2235:
2227:
2192:
2182:
2147:
2104:
2069:
2061:
2018:
1975:
1940:
1932:
1897:
1889:
1854:
1846:
1813:
1782:
1692:
1682:
1641:
1633:
1592:
1584:
1537:
1479:
1430:
425:
356:
300:
255:
160:
5789:
5652:
5506:
4804:
3340:
3335:
3258:
2696:
2692:
2371:
2354:
1787:
1770:
1466:
Horváth G, Serru V, Clay D, Billard M, Boucheix C, Rubinstein E (November 1998).
1275:
1251:
1181:
400:
184:
2109:
2092:
2023:
2006:
1588:
1435:
1418:
1363:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1345:
National Center for
Biotechnology Information, U.S. National Library of Medicine
5562:
5337:
5166:
5125:
4589:
4011:
3522:
3325:
2612:
2398:"Functional dissection of the CD21/CD19/TAPA-1/Leu-13 complex of B lymphocytes"
2328:
2311:
1980:
1963:
501:
1727:
1687:
6085:
5543:
5309:
5281:
4559:
4016:
3107:
2782:
2777:
1637:
1484:
1467:
1263:
612:
2283:
2187:
2050:"Epstein Barr virus/complement C3d receptor is an interferon alpha receptor"
583:
561:
439:
5771:
4915:
4223:
4213:
3744:
3710:
2978:
2973:
2961:
2943:
2938:
2848:
2413:
2231:
1936:
1706:
1655:
1606:
1541:
418:
197:
2461:
2431:
2380:
2337:
2302:
2249:
2206:
2161:
2118:
2083:
2032:
1989:
1954:
1911:
1868:
1825:
1796:
1493:
1468:"CD19 is linked to the integrin-associated tetraspans CD9, CD81, and CD82"
1444:
1404:"Entrez Gene: CR2 complement component (3d/Epstein Barr virus) receptor 2"
1099:
1094:
5818:
5766:
5662:
5600:
5516:
5132:
4925:
4574:
4352:
4327:
4026:
3648:
3574:
3048:
1964:"Interaction of iC3b with recombinant isotypic and chimeric forms of CR2"
1893:
1549:
1211:
The CR2 gene of primates produces only the smaller isoform, CR2; primate
932:
913:
5141:
5087:
5083:
5066:
4855:
4579:
4260:
4001:
3877:
3510:
3505:
3500:
3355:
3139:
2818:
2643:
1258:
infection. The pattern of the FDC meshwork may also be altered in some
317:
214:
164:
39:
105:
101:
97:
93:
89:
85:
5830:
4694:
4689:
4684:
4674:
4669:
4664:
4659:
2721:
1417:
Bradbury LE, Kansas GS, Levy S, Evans RL, Tedder TF (November 1992).
1174:
787:
384:
371:
283:
270:
172:
2562:
5880:
5834:
5000:
4900:
4714:
4699:
3902:
3897:
3805:
3495:
2882:
2716:
1259:
1083:
5533:
5997:
5992:
5987:
5977:
5962:
5947:
5942:
5932:
5361:
5295:
5227:
4950:
4945:
4940:
4840:
4654:
4644:
4471:
4450:
4445:
4413:
4218:
4138:
4133:
4128:
4123:
4118:
4036:
3729:
3569:
3564:
3559:
3554:
3549:
3020:
1740:
Leong, Anthony S-Y; Cooper, Kumarason; Leong, F Joel W-M (2003).
1573:"Comparative functional evolution of human and mouse CR1 and CR2"
1177:
1127:
899:
854:
772:
768:
1250:
This feature can be useful in examining tissue where the normal
152:
6070:
6065:
6060:
6055:
6050:
6040:
6035:
6030:
6025:
6020:
5753:
5744:
5637:
5304:
5158:
5075:
4890:
4850:
4835:
4819:
4814:
4794:
4789:
4724:
4532:
4502:
4466:
4457:
4270:
4238:
4102:
4097:
4067:
4046:
4006:
3966:
3832:
3810:
3769:
3693:
3688:
3683:
3678:
3673:
3668:
3537:
3532:
3527:
3475:
3460:
3330:
3320:
3283:
3278:
3196:
3191:
1150:
1067:
809:
592:
2486:
5725:
5721:
5397:
5317:
5092:
5015:
4990:
4910:
4905:
4895:
4885:
4870:
4865:
4860:
4845:
4799:
4784:
4749:
4734:
4729:
4719:
4639:
4634:
4629:
4608:
4604:
4594:
4507:
4408:
4403:
4362:
4312:
4307:
4302:
4297:
4282:
4275:
4255:
4243:
4186:
4181:
4176:
4166:
4161:
4154:
4092:
4082:
4077:
4072:
4062:
4041:
4031:
3996:
3991:
3986:
3981:
3976:
3931:
3926:
3892:
3857:
3852:
3847:
3837:
3825:
3820:
3800:
3795:
3790:
3785:
3739:
3631:
3626:
3445:
3429:
3422:
3417:
3412:
3407:
3402:
3397:
3372:
3350:
3345:
3238:
3164:
3159:
3149:
2924:
1876:
Matsumoto AK, Kopicky-Burd J, Carter RH, et al. (1991).
1382:
p. 281–298, Philadelphia: Lippincott
Williams & Wilkins,
1918:
1744:(2 ed.). Greenwich Medical Media, Ltd. pp. 93–94.
5866:
5861:
5808:
5803:
5793:
5729:
5701:
5685:
5681:
5595:
5572:
5567:
5539:
5457:
5435:
5410:
5405:
5387:
5383:
5378:
5373:
5369:
5342:
5332:
5327:
5322:
5245:
5235:
5217:
5212:
5202:
5136:
5115:
5105:
5100:
5010:
5005:
4995:
4985:
4980:
4975:
4930:
4920:
4880:
4809:
4779:
4774:
4769:
4764:
4759:
4754:
4709:
4679:
4584:
4552:
4547:
4527:
4517:
4512:
4497:
4492:
4393:
4388:
4357:
4337:
4332:
4322:
4317:
4196:
4149:
4109:
3764:
3759:
3754:
3749:
3734:
3725:
3720:
3715:
3700:
3658:
3653:
3643:
3638:
3621:
3616:
3611:
3606:
3601:
3596:
3591:
3586:
3581:
3517:
3490:
3485:
3480:
3455:
3450:
3387:
3382:
3377:
3367:
3362:
3315:
3310:
3305:
3295:
3290:
3273:
3268:
3263:
3253:
3248:
3233:
3228:
3223:
3213:
3208:
3203:
3186:
3181:
3176:
3127:
3095:
3090:
3085:
3068:
3063:
3058:
3053:
2928:
2857:
2751:
1875:
1170:
1166:
1142:
1131:
1526:
5840:
5826:
5261:
5192:
5187:
5182:
5175:
5056:
4522:
3134:
3122:
3117:
3112:
3102:
3075:
3043:
2747:
2675:
2670:
1255:
1146:
2396:
Matsumoto AK, Martin DR, Carter RH, et al. (1993).
408:
2257:
Weis JJ, Fearon DT, Klickstein LB, et al. (1986).
1919:
Tuveson DA, Ahearn JM, Matsumoto AK, Fearon DT (1991).
1465:
1416:
2438:
2168:
1768:
2395:
2214:
Weis JJ, Toothaker LE, Smith JA, et al. (1988).
2134:
Fujisaku A, Harley JB, Frank MB, et al. (1989).
573:
2353:
Aubry JP, Pochon S, Gauchat JF, et al. (1994).
2256:
2048:
Delcayre AX, Salas F, Mathur S, et al. (1991).
2133:
2091:Kurtz CB, Paul MS, Aegerter M, et al. (1989).
2047:
2005:Barel M, Gauffre A, Lyamani F, et al. (1991).
2004:
1620:Donius LR, Handy JM, Weis JJ, Weis JH (July 2013).
1619:
2352:
2310:Weis JH, Morton CC, Bruns GA, et al. (1987).
2213:
1319:
1317:
1315:
1298:
1296:
1294:
2169:Moore MD, Cooper NR, Tack BF, Nemerow GR (1988).
2090:
1961:
1803:
1769:Cooper NR, Bradt BM, Rhim JS, Nemerow GR (1990).
355:
254:
6083:
1254:have been effaced by disease processes, such as
1180:through attached C3d (or iC3b or C3dg) when the
2309:
1312:
1291:
1169:, and, on mature B cells, forms a complex with
1833:Levy E, Ambrus J, Kahl L, et al. (1992).
1832:
1380:Samter's Immunologic Diseases, 6th ed. Vol. 1,
1324:GRCm38: Ensembl release 89: ENSMUSG00000026616
748:complement receptor mediated signaling pathway
5484:
5042:
3005:
2578:
2502:
1398:
1396:
1719:: CS1 maint: multiple names: authors list (
1613:
1570:
1564:
1728:http://creativecommons.org/licenses/by/4.0/
1303:GRCh38: Ensembl release 89: ENSG00000117322
5491:
5477:
5049:
5035:
3012:
2998:
2585:
2571:
2509:
2495:
1520:
1508:Cellular and Molecular Immunology, 5th ed.
1459:
1410:
1393:
3029:list of human clusters of differentiation
2479:at the U.S. National Library of Medicine
2421:
2370:
2327:
2292:
2282:
2239:
2196:
2186:
2151:
2108:
2073:
2022:
1979:
1944:
1901:
1858:
1786:
1696:
1686:
1645:
1596:
1483:
1434:
646:transmembrane signaling receptor activity
1230:
723:complement activation, classical pathway
1962:Kalli KR, Ahearn JM, Fearon DT (1991).
1571:Jacobson AC, Weis JH (September 2008).
1374:
1372:
1226:
14:
6084:
1126:(cluster of differentiation 21), is a
5472:
5030:
2993:
2592:
2566:
2490:
1733:
1130:that in humans is encoded by the CR2
360:
321:
316:
259:
218:
213:
1500:
1369:
1203:respectively. A transcript with an
758:regulation of complement activation
24:
2066:10.1002/j.1460-2075.1991.tb08025.x
1851:10.1111/j.1365-2249.1992.tb07935.x
1761:
25:
6108:
5617:Polymeric immunoglobulin receptor
2470:
631:protein homodimerization activity
2542:
2527:
582:
344:
337:
331:
308:
243:
236:
230:
205:
38:
2516:
1662:
1156:
5829:(with two glycoprotein chains
1506:Abbas AK, Lichtman AH (2003).
1351:
1333:
672:integral component of membrane
593:More reference expression data
562:More reference expression data
13:
1:
5925:Killer-cell IG-like receptors
2153:10.1016/S0021-9258(18)94149-9
1742:Manual of Diagnostic Cytology
1285:
536:tunica media of zone of aorta
329:
228:
2454:10.1016/0161-5890(95)00005-Y
2372:10.4049/jimmunol.152.12.5806
2263:Proc. Natl. Acad. Sci. U.S.A
2175:Proc. Natl. Acad. Sci. U.S.A
1818:10.1016/0161-5890(92)90044-X
1788:10.1111/1523-1747.ep12876069
1194:receptors on human B cells.
651:complement receptor activity
7:
6092:Genes on human chromosome 1
6013:Leukocyte IG-like receptors
3025:clusters of differentiation
2537:: CR2-C3D COMPLEX STRUCTURE
2110:10.4049/jimmunol.143.6.2058
2024:10.4049/jimmunol.147.4.1286
1589:10.4049/jimmunol.181.5.2953
1436:10.4049/jimmunol.149.9.2841
1262:conditions, such as B-cell
1197:
1120:Epstein-Barr virus receptor
524:subcutaneous adipose tissue
478:superficial temporal artery
10:
6113:
5504:immunoglobulin superfamily
5058:Cluster of differentiation
2329:10.4049/jimmunol.138.1.312
1981:10.4049/jimmunol.147.2.590
1221:follicular dendritic cells
1112:Complement receptor type 2
728:viral entry into host cell
544:tunica adventitia of aorta
6011:
5923:
5902:
5849:
5817:
5782:
5752:
5743:
5714:
5694:
5670:
5661:
5645:
5636:
5629:
5609:
5586:
5553:
5524:
5513:
5448:
5423:
5396:
5360:
5351:
5303:
5294:
5274:
5254:
5226:
5157:
5150:
5074:
5065:
4828:
4622:
4371:
4055:
3778:
3438:
3036:
2954:
2891:
2854:Decay-accelerating factor
2838:
2791:
2730:
2633:
2626:
2600:
2522:
1771:"CR2 complement receptor"
1688:10.1186/s12957-019-1659-8
1359:"Mouse PubMed Reference:"
1341:"Human PubMed Reference:"
1098:
1093:
1089:
1082:
1066:
1060:Chr 1: 194.82 – 194.86 Mb
1053:Chr 1: 207.45 – 207.49 Mb
1047:
1034:
1030:
1009:
1005:
998:
979:
975:
954:
950:
943:
930:
926:
911:
907:
898:
885:
881:
866:
862:
853:
840:
836:
821:
817:
808:
793:
786:
782:
766:
611:
607:
590:
581:
572:
559:
508:
499:
470:epithelium of nasopharynx
446:
437:
407:
399:
395:
378:
365:
328:
307:
298:
294:
277:
264:
227:
204:
195:
191:
146:
143:
133:
126:
121:
82:
77:
60:
55:
50:
46:
37:
32:
2481:Medical Subject Headings
1638:10.4049/jimmunol.1203176
1510:Philadelphia: Saunders,
1485:10.1074/jbc.273.46.30537
1145:(inactive derivative of
5500:Transmembrane receptors
2284:10.1073/pnas.83.15.5639
2188:10.1073/pnas.84.24.9194
1137:CR2 is involved in the
1116:complement C3d receptor
636:virus receptor activity
27:Protein found in humans
2477:Complement+Receptors+2
2414:10.1084/jem.178.4.1407
2232:10.1084/jem.167.3.1047
1937:10.1084/jem.173.5.1083
1781:(6 Suppl): s112–s117.
1542:10.1002/ijc.2910170602
1236:
1219:produced primarily by
1161:Complement receptor 2
738:innate immune response
733:B cell differentiation
528:neural layer of retina
516:mesenteric lymph nodes
1234:
1213:complement receptor 1
1114:(CR2), also known as
708:immune system process
687:extracellular exosome
2893:Complement receptors
1894:10.1084/jem.173.1.55
1268:mantle cell lymphoma
1241:immunohistochemistry
1227:Immunohistochemistry
713:B cell proliferation
362:1 H6|1 98.44 cM
323:Chromosome 1 (mouse)
221:Chromosome 1 (human)
78:List of PDB id codes
51:Available structures
5850:Accessory molecules
5715:Accessory molecules
2275:1986PNAS...83.5639W
1775:J. Invest. Dermatol
1280:Castleman's disease
1272:follicular lymphoma
753:signal transduction
5914:cytokine receptors
5514:Antibody receptor:
2722:Factor P/Properdin
2627:Activators/enzymes
1839:Clin. Exp. Immunol
1675:World J Surg Oncol
1237:
1205:open reading frame
1188:Epstein-Barr virus
888:ENSMUSG00000026616
701:Biological process
665:Cellular component
641:complement binding
619:Molecular function
6097:Complement system
6079:
6078:
5904:Cytokine receptor
5898:
5897:
5894:
5893:
5739:
5738:
5710:
5709:
5625:
5624:
5466:
5465:
5444:
5443:
5424:All (pan-myeloid)
5419:
5418:
5290:
5289:
5270:
5269:
5024:
5023:
2987:
2986:
2834:
2833:
2594:Complement system
2560:
2559:
1751:978-1-84110-100-2
1149:), C3dg, or C3d.
1139:complement system
1109:
1108:
1105:
1104:
1078:
1077:
1043:
1042:
1024:
1023:
994:
993:
969:
968:
939:
938:
920:
919:
894:
893:
875:
874:
849:
848:
830:
829:
778:
777:
603:
602:
599:
598:
568:
567:
555:
554:
493:
492:
391:
390:
290:
289:
117:
116:
113:
112:
61:Ortholog search:
16:(Redirected from
6104:
5783:Antigen receptor
5750:
5749:
5668:
5667:
5646:Antigen receptor
5643:
5642:
5634:
5633:
5630:Antigen receptor
5588:Alpha (α)/mu (μ)
5522:
5521:
5507:immune receptors
5493:
5486:
5479:
5470:
5469:
5358:
5357:
5301:
5300:
5155:
5154:
5072:
5071:
5051:
5044:
5037:
5028:
5027:
3014:
3007:
3000:
2991:
2990:
2968:immune adherence
2631:
2630:
2587:
2580:
2573:
2564:
2563:
2546:
2531:
2511:
2504:
2497:
2488:
2487:
2465:
2435:
2425:
2392:
2374:
2349:
2331:
2306:
2296:
2286:
2253:
2243:
2210:
2200:
2190:
2165:
2155:
2130:
2112:
2087:
2077:
2044:
2026:
2001:
1983:
1958:
1948:
1915:
1905:
1872:
1862:
1829:
1800:
1790:
1756:
1755:
1737:
1731:
1724:
1718:
1710:
1700:
1690:
1666:
1660:
1659:
1649:
1617:
1611:
1610:
1600:
1568:
1562:
1561:
1524:
1518:
1504:
1498:
1497:
1487:
1478:(46): 30537–43.
1463:
1457:
1456:
1438:
1414:
1408:
1407:
1400:
1391:
1376:
1367:
1366:
1355:
1349:
1348:
1337:
1331:
1321:
1310:
1300:
1276:T cell lymphomas
1252:germinal centres
1243:is performed on
1091:
1090:
1062:
1055:
1038:
1028:
1027:
1019:
1003:
1002:
999:RefSeq (protein)
989:
973:
972:
964:
948:
947:
924:
923:
905:
904:
879:
878:
860:
859:
834:
833:
815:
814:
784:
783:
682:receptor complex
609:
608:
595:
586:
579:
578:
564:
504:
502:Top expressed in
497:
496:
450:secondary oocyte
442:
440:Top expressed in
435:
434:
414:
413:
397:
396:
387:
374:
363:
348:
341:
335:
324:
312:
296:
295:
286:
273:
262:
247:
240:
234:
223:
209:
193:
192:
187:
138:
131:
108:
75:
74:
69:
48:
47:
42:
30:
29:
21:
6112:
6111:
6107:
6106:
6105:
6103:
6102:
6101:
6082:
6081:
6080:
6075:
6007:
5919:
5890:
5845:
5813:
5778:
5735:
5706:
5690:
5657:
5621:
5605:
5582:
5549:
5515:
5509:
5497:
5467:
5462:
5440:
5415:
5392:
5347:
5308:
5286:
5266:
5250:
5222:
5146:
5061:
5055:
5025:
5020:
4824:
4618:
4367:
4051:
3774:
3434:
3032:
3018:
2988:
2983:
2950:
2887:
2830:
2787:
2726:
2622:
2596:
2591:
2561:
2556:
2553:
2547:
2538:
2532:
2518:
2515:
2473:
2468:
2365:(12): 5806–13.
2269:(15): 5639–43.
1764:
1762:Further reading
1759:
1752:
1738:
1734:
1725:
1712:
1711:
1667:
1663:
1618:
1614:
1569:
1565:
1525:
1521:
1505:
1501:
1464:
1460:
1415:
1411:
1402:
1401:
1394:
1377:
1370:
1357:
1356:
1352:
1339:
1338:
1334:
1322:
1313:
1301:
1292:
1288:
1245:frozen sections
1229:
1200:
1182:B-cell receptor
1159:
1100:View/Edit Mouse
1095:View/Edit Human
1058:
1051:
1048:Location (UCSC)
1036:
1015:
1011:
985:
981:
960:
956:
869:ENSG00000117322
762:
718:immune response
696:
692:plasma membrane
660:
656:protein binding
591:
560:
551:
546:
542:
538:
534:
530:
526:
522:
518:
514:
500:
489:
484:
480:
476:
472:
468:
466:mucosa of ileum
464:
460:
456:
452:
438:
382:
369:
361:
351:
350:
349:
342:
322:
299:Gene location (
281:
268:
260:
250:
249:
248:
241:
219:
196:Gene location (
185:CR2 - orthologs
147:
134:
127:
84:
62:
28:
23:
22:
15:
12:
11:
5:
6110:
6100:
6099:
6094:
6077:
6076:
6074:
6073:
6068:
6063:
6058:
6053:
6048:
6043:
6038:
6033:
6028:
6023:
6017:
6015:
6009:
6008:
6006:
6005:
6000:
5995:
5990:
5985:
5980:
5975:
5970:
5965:
5960:
5955:
5950:
5945:
5940:
5935:
5929:
5927:
5921:
5920:
5918:
5917:
5908:
5906:
5900:
5899:
5896:
5895:
5892:
5891:
5889:
5888:
5874:
5869:
5864:
5859:
5853:
5851:
5847:
5846:
5844:
5843:
5838:
5823:
5821:
5815:
5814:
5812:
5811:
5806:
5801:
5796:
5786:
5784:
5780:
5779:
5777:
5776:
5775:
5774:
5769:
5758:
5756:
5747:
5741:
5740:
5737:
5736:
5734:
5733:
5718:
5716:
5712:
5711:
5708:
5707:
5705:
5704:
5698:
5696:
5692:
5691:
5689:
5688:
5674:
5672:
5665:
5659:
5658:
5656:
5655:
5649:
5647:
5640:
5631:
5627:
5626:
5623:
5622:
5620:
5619:
5613:
5611:
5607:
5606:
5604:
5603:
5598:
5592:
5590:
5584:
5583:
5581:
5580:
5575:
5570:
5565:
5559:
5557:
5551:
5550:
5548:
5547:
5536:
5530:
5528:
5519:
5511:
5510:
5496:
5495:
5488:
5481:
5473:
5464:
5463:
5461:
5460:
5454:
5452:
5446:
5445:
5442:
5441:
5439:
5438:
5433:
5427:
5425:
5421:
5420:
5417:
5416:
5414:
5413:
5408:
5402:
5400:
5394:
5393:
5391:
5390:
5381:
5376:
5366:
5364:
5355:
5349:
5348:
5346:
5345:
5340:
5335:
5330:
5325:
5320:
5314:
5312:
5298:
5292:
5291:
5288:
5287:
5285:
5284:
5278:
5276:
5272:
5271:
5268:
5267:
5265:
5264:
5258:
5256:
5252:
5251:
5249:
5248:
5243:
5238:
5232:
5230:
5224:
5223:
5221:
5220:
5215:
5210:
5205:
5200:
5195:
5190:
5185:
5179:
5178:
5173:
5167:Pan-T antigens
5163:
5161:
5152:
5148:
5147:
5145:
5144:
5139:
5129:
5128:
5123:
5118:
5113:
5108:
5103:
5096:
5095:
5090:
5080:
5078:
5069:
5063:
5062:
5054:
5053:
5046:
5039:
5031:
5022:
5021:
5019:
5018:
5013:
5008:
5003:
4998:
4993:
4988:
4983:
4978:
4973:
4968:
4963:
4958:
4953:
4948:
4943:
4938:
4933:
4928:
4923:
4918:
4913:
4908:
4903:
4898:
4893:
4888:
4883:
4878:
4873:
4868:
4863:
4858:
4853:
4848:
4843:
4838:
4832:
4830:
4826:
4825:
4823:
4822:
4817:
4812:
4807:
4802:
4797:
4792:
4787:
4782:
4777:
4772:
4767:
4762:
4757:
4752:
4747:
4742:
4737:
4732:
4727:
4722:
4717:
4712:
4707:
4702:
4697:
4692:
4687:
4682:
4677:
4672:
4667:
4662:
4657:
4652:
4647:
4642:
4637:
4632:
4626:
4624:
4620:
4619:
4617:
4616:
4611:
4602:
4597:
4592:
4587:
4582:
4577:
4572:
4567:
4562:
4557:
4556:
4555:
4550:
4540:
4535:
4530:
4525:
4520:
4515:
4510:
4505:
4500:
4495:
4490:
4485:
4480:
4475:
4469:
4460:
4455:
4454:
4453:
4448:
4438:
4433:
4432:
4431:
4426:
4416:
4411:
4406:
4401:
4396:
4391:
4386:
4381:
4375:
4373:
4369:
4368:
4366:
4365:
4360:
4355:
4350:
4345:
4340:
4335:
4330:
4325:
4320:
4315:
4310:
4305:
4300:
4295:
4290:
4285:
4280:
4279:
4278:
4273:
4263:
4258:
4253:
4248:
4247:
4246:
4241:
4236:
4226:
4221:
4216:
4211:
4206:
4205:
4204:
4199:
4189:
4184:
4179:
4174:
4169:
4164:
4159:
4158:
4157:
4152:
4142:
4136:
4131:
4126:
4121:
4112:
4107:
4106:
4105:
4100:
4095:
4085:
4080:
4075:
4070:
4065:
4059:
4057:
4053:
4052:
4050:
4049:
4044:
4039:
4034:
4029:
4024:
4019:
4014:
4009:
4004:
3999:
3994:
3989:
3984:
3979:
3974:
3969:
3964:
3959:
3954:
3949:
3944:
3939:
3934:
3929:
3924:
3923:
3922:
3917:
3907:
3906:
3905:
3900:
3890:
3885:
3880:
3875:
3870:
3865:
3860:
3855:
3850:
3845:
3840:
3835:
3830:
3829:
3828:
3823:
3813:
3808:
3803:
3798:
3793:
3788:
3782:
3780:
3776:
3775:
3773:
3772:
3767:
3762:
3757:
3752:
3747:
3742:
3737:
3732:
3723:
3718:
3713:
3708:
3703:
3698:
3697:
3696:
3691:
3686:
3681:
3676:
3671:
3661:
3656:
3651:
3646:
3641:
3636:
3635:
3634:
3629:
3619:
3614:
3609:
3604:
3599:
3594:
3589:
3584:
3579:
3578:
3577:
3572:
3567:
3562:
3557:
3552:
3542:
3541:
3540:
3535:
3530:
3520:
3515:
3514:
3513:
3508:
3503:
3493:
3488:
3483:
3478:
3473:
3468:
3463:
3458:
3453:
3448:
3442:
3440:
3436:
3435:
3433:
3432:
3427:
3426:
3425:
3420:
3415:
3410:
3405:
3400:
3390:
3385:
3380:
3375:
3370:
3365:
3360:
3359:
3358:
3353:
3348:
3343:
3333:
3328:
3323:
3318:
3313:
3308:
3303:
3298:
3293:
3288:
3287:
3286:
3281:
3271:
3266:
3261:
3256:
3251:
3246:
3241:
3236:
3231:
3226:
3221:
3216:
3211:
3206:
3201:
3200:
3199:
3194:
3184:
3179:
3174:
3169:
3168:
3167:
3162:
3157:
3152:
3142:
3137:
3132:
3131:
3130:
3120:
3115:
3110:
3105:
3100:
3099:
3098:
3093:
3088:
3078:
3073:
3072:
3071:
3066:
3061:
3056:
3051:
3040:
3038:
3034:
3033:
3017:
3016:
3009:
3002:
2994:
2985:
2984:
2982:
2981:
2976:
2970:
2965:
2958:
2956:
2952:
2951:
2949:
2948:
2947:
2946:
2941:
2931:
2918:
2913:
2908:
2903:
2897:
2895:
2889:
2888:
2886:
2885:
2876:
2875:
2866:
2865:
2860:
2851:
2842:
2840:
2836:
2835:
2832:
2831:
2829:
2828:
2827:
2826:
2821:
2816:
2811:
2806:
2795:
2793:
2789:
2788:
2786:
2785:
2780:
2774:
2773:
2772:
2771:
2766:
2756:
2755:
2754:
2745:
2734:
2732:
2728:
2727:
2725:
2724:
2719:
2714:
2705:
2704:
2699:
2686:
2685:
2680:
2679:
2678:
2673:
2663:
2662:
2661:
2656:
2651:
2637:
2635:
2628:
2624:
2623:
2621:
2620:
2615:
2610:
2604:
2602:
2598:
2597:
2590:
2589:
2582:
2575:
2567:
2558:
2557:
2555:
2554:
2548:
2541:
2539:
2533:
2526:
2523:
2520:
2519:
2514:
2513:
2506:
2499:
2491:
2485:
2484:
2472:
2471:External links
2469:
2467:
2466:
2436:
2408:(4): 1407–17.
2393:
2350:
2307:
2254:
2226:(3): 1047–66.
2211:
2181:(24): 9194–8.
2166:
2146:(4): 2118–25.
2131:
2103:(6): 2058–67.
2088:
2045:
2017:(4): 1286–91.
2002:
1959:
1916:
1873:
1830:
1812:(9): 1113–20.
1801:
1765:
1763:
1760:
1758:
1757:
1750:
1732:
1661:
1612:
1563:
1536:(6): 693–700.
1530:Int. J. Cancer
1519:
1499:
1458:
1429:(9): 2841–50.
1409:
1392:
1368:
1350:
1332:
1311:
1289:
1287:
1284:
1264:MALT lymphomas
1228:
1225:
1199:
1196:
1158:
1155:
1141:. It binds to
1107:
1106:
1103:
1102:
1097:
1087:
1086:
1080:
1079:
1076:
1075:
1073:
1071:
1064:
1063:
1056:
1049:
1045:
1044:
1041:
1040:
1032:
1031:
1025:
1022:
1021:
1007:
1006:
1000:
996:
995:
992:
991:
977:
976:
970:
967:
966:
952:
951:
945:
941:
940:
937:
936:
928:
927:
921:
918:
917:
909:
908:
902:
896:
895:
892:
891:
883:
882:
876:
873:
872:
864:
863:
857:
851:
850:
847:
846:
838:
837:
831:
828:
827:
819:
818:
812:
806:
805:
800:
795:
791:
790:
780:
779:
776:
775:
764:
763:
761:
760:
755:
750:
745:
740:
735:
730:
725:
720:
715:
710:
704:
702:
698:
697:
695:
694:
689:
684:
679:
674:
668:
666:
662:
661:
659:
658:
653:
648:
643:
638:
633:
628:
622:
620:
616:
615:
605:
604:
601:
600:
597:
596:
588:
587:
576:
570:
569:
566:
565:
557:
556:
553:
552:
550:
549:
545:
541:
537:
533:
529:
525:
521:
517:
513:
509:
506:
505:
494:
491:
490:
488:
487:
483:
479:
475:
471:
467:
463:
459:
455:
451:
447:
444:
443:
431:
430:
422:
411:
405:
404:
401:RNA expression
393:
392:
389:
388:
380:
376:
375:
367:
364:
359:
353:
352:
343:
336:
330:
326:
325:
320:
314:
313:
305:
304:
292:
291:
288:
287:
279:
275:
274:
266:
263:
258:
252:
251:
242:
235:
229:
225:
224:
217:
211:
210:
202:
201:
189:
188:
145:
141:
140:
132:
124:
123:
119:
118:
115:
114:
111:
110:
80:
79:
71:
70:
59:
53:
52:
44:
43:
35:
34:
26:
9:
6:
4:
3:
2:
6109:
6098:
6095:
6093:
6090:
6089:
6087:
6072:
6069:
6067:
6064:
6062:
6059:
6057:
6054:
6052:
6049:
6047:
6044:
6042:
6039:
6037:
6034:
6032:
6029:
6027:
6024:
6022:
6019:
6018:
6016:
6014:
6010:
6004:
6001:
5999:
5996:
5994:
5991:
5989:
5986:
5984:
5981:
5979:
5976:
5974:
5971:
5969:
5966:
5964:
5961:
5959:
5956:
5954:
5951:
5949:
5946:
5944:
5941:
5939:
5936:
5934:
5931:
5930:
5928:
5926:
5922:
5916:
5915:
5910:
5909:
5907:
5905:
5901:
5886:
5882:
5879:(also called
5878:
5875:
5873:
5870:
5868:
5865:
5863:
5860:
5858:
5855:
5854:
5852:
5848:
5842:
5839:
5836:
5832:
5828:
5825:
5824:
5822:
5820:
5816:
5810:
5807:
5805:
5802:
5800:
5797:
5795:
5791:
5788:
5787:
5785:
5781:
5773:
5770:
5768:
5765:
5764:
5763:
5760:
5759:
5757:
5755:
5751:
5748:
5746:
5742:
5731:
5727:
5723:
5720:
5719:
5717:
5713:
5703:
5700:
5699:
5697:
5693:
5687:
5683:
5679:
5676:
5675:
5673:
5669:
5666:
5664:
5660:
5654:
5651:
5650:
5648:
5644:
5641:
5639:
5635:
5632:
5628:
5618:
5615:
5614:
5612:
5608:
5602:
5599:
5597:
5594:
5593:
5591:
5589:
5585:
5579:
5576:
5574:
5571:
5569:
5566:
5564:
5561:
5560:
5558:
5556:
5552:
5545:
5544:C-type lectin
5541:
5537:
5535:
5532:
5531:
5529:
5527:
5523:
5520:
5518:
5512:
5508:
5505:
5501:
5494:
5489:
5487:
5482:
5480:
5475:
5474:
5471:
5459:
5456:
5455:
5453:
5451:
5447:
5437:
5434:
5432:
5429:
5428:
5426:
5422:
5412:
5409:
5407:
5404:
5403:
5401:
5399:
5395:
5389:
5385:
5382:
5380:
5377:
5375:
5371:
5368:
5367:
5365:
5363:
5359:
5356:
5354:
5350:
5344:
5341:
5339:
5336:
5334:
5331:
5329:
5326:
5324:
5321:
5319:
5316:
5315:
5313:
5311:
5310:Myelomonocyte
5306:
5302:
5299:
5297:
5293:
5283:
5280:
5279:
5277:
5273:
5263:
5260:
5259:
5257:
5253:
5247:
5244:
5242:
5239:
5237:
5234:
5233:
5231:
5229:
5225:
5219:
5216:
5214:
5211:
5209:
5206:
5204:
5201:
5199:
5196:
5194:
5191:
5189:
5186:
5184:
5181:
5180:
5177:
5174:
5172:
5168:
5165:
5164:
5162:
5160:
5156:
5153:
5149:
5143:
5140:
5138:
5134:
5131:
5130:
5127:
5124:
5122:
5119:
5117:
5114:
5112:
5109:
5107:
5104:
5102:
5098:
5097:
5094:
5091:
5089:
5085:
5082:
5081:
5079:
5077:
5073:
5070:
5068:
5064:
5059:
5052:
5047:
5045:
5040:
5038:
5033:
5032:
5029:
5017:
5014:
5012:
5009:
5007:
5004:
5002:
4999:
4997:
4994:
4992:
4989:
4987:
4984:
4982:
4979:
4977:
4974:
4972:
4969:
4967:
4964:
4962:
4959:
4957:
4954:
4952:
4949:
4947:
4944:
4942:
4939:
4937:
4934:
4932:
4929:
4927:
4924:
4922:
4919:
4917:
4914:
4912:
4909:
4907:
4904:
4902:
4899:
4897:
4894:
4892:
4889:
4887:
4884:
4882:
4879:
4877:
4874:
4872:
4869:
4867:
4864:
4862:
4859:
4857:
4854:
4852:
4849:
4847:
4844:
4842:
4839:
4837:
4834:
4833:
4831:
4827:
4821:
4818:
4816:
4813:
4811:
4808:
4806:
4803:
4801:
4798:
4796:
4793:
4791:
4788:
4786:
4783:
4781:
4778:
4776:
4773:
4771:
4768:
4766:
4763:
4761:
4758:
4756:
4753:
4751:
4748:
4746:
4743:
4741:
4738:
4736:
4733:
4731:
4728:
4726:
4723:
4721:
4718:
4716:
4713:
4711:
4708:
4706:
4703:
4701:
4698:
4696:
4693:
4691:
4688:
4686:
4683:
4681:
4678:
4676:
4673:
4671:
4668:
4666:
4663:
4661:
4658:
4656:
4653:
4651:
4648:
4646:
4643:
4641:
4638:
4636:
4633:
4631:
4628:
4627:
4625:
4621:
4615:
4612:
4610:
4606:
4603:
4601:
4598:
4596:
4593:
4591:
4588:
4586:
4583:
4581:
4578:
4576:
4573:
4571:
4568:
4566:
4563:
4561:
4558:
4554:
4551:
4549:
4546:
4545:
4544:
4541:
4539:
4536:
4534:
4531:
4529:
4526:
4524:
4521:
4519:
4516:
4514:
4511:
4509:
4506:
4504:
4501:
4499:
4496:
4494:
4491:
4489:
4486:
4484:
4481:
4479:
4476:
4473:
4470:
4468:
4464:
4461:
4459:
4456:
4452:
4449:
4447:
4444:
4443:
4442:
4439:
4437:
4434:
4430:
4427:
4425:
4422:
4421:
4420:
4417:
4415:
4412:
4410:
4407:
4405:
4402:
4400:
4397:
4395:
4392:
4390:
4387:
4385:
4382:
4380:
4377:
4376:
4374:
4370:
4364:
4361:
4359:
4356:
4354:
4351:
4349:
4346:
4344:
4341:
4339:
4336:
4334:
4331:
4329:
4326:
4324:
4321:
4319:
4316:
4314:
4311:
4309:
4306:
4304:
4301:
4299:
4296:
4294:
4291:
4289:
4286:
4284:
4281:
4277:
4274:
4272:
4269:
4268:
4267:
4264:
4262:
4259:
4257:
4254:
4252:
4249:
4245:
4242:
4240:
4237:
4235:
4232:
4231:
4230:
4227:
4225:
4222:
4220:
4217:
4215:
4212:
4210:
4207:
4203:
4200:
4198:
4195:
4194:
4193:
4190:
4188:
4185:
4183:
4180:
4178:
4175:
4173:
4170:
4168:
4165:
4163:
4160:
4156:
4153:
4151:
4148:
4147:
4146:
4143:
4140:
4137:
4135:
4132:
4130:
4127:
4125:
4122:
4120:
4116:
4113:
4111:
4108:
4104:
4101:
4099:
4096:
4094:
4091:
4090:
4089:
4086:
4084:
4081:
4079:
4076:
4074:
4071:
4069:
4066:
4064:
4061:
4060:
4058:
4054:
4048:
4045:
4043:
4040:
4038:
4035:
4033:
4030:
4028:
4025:
4023:
4020:
4018:
4015:
4013:
4010:
4008:
4005:
4003:
4000:
3998:
3995:
3993:
3990:
3988:
3985:
3983:
3980:
3978:
3975:
3973:
3970:
3968:
3965:
3963:
3960:
3958:
3955:
3953:
3950:
3948:
3945:
3943:
3940:
3938:
3935:
3933:
3930:
3928:
3925:
3921:
3918:
3916:
3913:
3912:
3911:
3908:
3904:
3901:
3899:
3896:
3895:
3894:
3891:
3889:
3886:
3884:
3881:
3879:
3876:
3874:
3871:
3869:
3866:
3864:
3861:
3859:
3856:
3854:
3851:
3849:
3846:
3844:
3841:
3839:
3836:
3834:
3831:
3827:
3824:
3822:
3819:
3818:
3817:
3814:
3812:
3809:
3807:
3804:
3802:
3799:
3797:
3794:
3792:
3789:
3787:
3784:
3783:
3781:
3777:
3771:
3768:
3766:
3763:
3761:
3758:
3756:
3753:
3751:
3748:
3746:
3743:
3741:
3738:
3736:
3733:
3731:
3727:
3724:
3722:
3719:
3717:
3714:
3712:
3709:
3707:
3704:
3702:
3699:
3695:
3692:
3690:
3687:
3685:
3682:
3680:
3677:
3675:
3672:
3670:
3667:
3666:
3665:
3662:
3660:
3657:
3655:
3652:
3650:
3647:
3645:
3642:
3640:
3637:
3633:
3630:
3628:
3625:
3624:
3623:
3620:
3618:
3615:
3613:
3610:
3608:
3605:
3603:
3600:
3598:
3595:
3593:
3590:
3588:
3585:
3583:
3580:
3576:
3573:
3571:
3568:
3566:
3563:
3561:
3558:
3556:
3553:
3551:
3548:
3547:
3546:
3543:
3539:
3536:
3534:
3531:
3529:
3526:
3525:
3524:
3521:
3519:
3516:
3512:
3509:
3507:
3504:
3502:
3499:
3498:
3497:
3494:
3492:
3489:
3487:
3484:
3482:
3479:
3477:
3474:
3472:
3469:
3467:
3464:
3462:
3459:
3457:
3454:
3452:
3449:
3447:
3444:
3443:
3441:
3437:
3431:
3428:
3424:
3421:
3419:
3416:
3414:
3411:
3409:
3406:
3404:
3401:
3399:
3396:
3395:
3394:
3391:
3389:
3386:
3384:
3381:
3379:
3376:
3374:
3371:
3369:
3366:
3364:
3361:
3357:
3354:
3352:
3349:
3347:
3344:
3342:
3339:
3338:
3337:
3334:
3332:
3329:
3327:
3324:
3322:
3319:
3317:
3314:
3312:
3309:
3307:
3304:
3302:
3299:
3297:
3294:
3292:
3289:
3285:
3282:
3280:
3277:
3276:
3275:
3272:
3270:
3267:
3265:
3262:
3260:
3257:
3255:
3252:
3250:
3247:
3245:
3242:
3240:
3237:
3235:
3232:
3230:
3227:
3225:
3222:
3220:
3217:
3215:
3212:
3210:
3207:
3205:
3202:
3198:
3195:
3193:
3190:
3189:
3188:
3185:
3183:
3180:
3178:
3175:
3173:
3170:
3166:
3163:
3161:
3158:
3156:
3153:
3151:
3148:
3147:
3146:
3143:
3141:
3138:
3136:
3133:
3129:
3126:
3125:
3124:
3121:
3119:
3116:
3114:
3111:
3109:
3106:
3104:
3101:
3097:
3094:
3092:
3089:
3087:
3084:
3083:
3082:
3079:
3077:
3074:
3070:
3067:
3065:
3062:
3060:
3057:
3055:
3052:
3050:
3047:
3046:
3045:
3042:
3041:
3039:
3035:
3030:
3026:
3022:
3015:
3010:
3008:
3003:
3001:
2996:
2995:
2992:
2980:
2977:
2975:
2971:
2969:
2966:
2963:
2960:
2959:
2957:
2953:
2945:
2942:
2940:
2937:
2936:
2935:
2934:Anaphylatoxin
2932:
2930:
2926:
2922:
2919:
2917:
2914:
2912:
2909:
2907:
2904:
2902:
2899:
2898:
2896:
2894:
2890:
2884:
2881:
2878:
2877:
2874:
2871:
2868:
2867:
2864:
2861:
2859:
2855:
2852:
2850:
2847:
2844:
2843:
2841:
2837:
2825:
2822:
2820:
2817:
2815:
2812:
2810:
2807:
2805:
2802:
2801:
2800:
2797:
2796:
2794:
2790:
2784:
2783:C5-convertase
2781:
2779:
2778:C3-convertase
2776:
2775:
2770:
2767:
2765:
2762:
2761:
2760:
2757:
2753:
2749:
2746:
2744:
2741:
2740:
2739:
2736:
2735:
2733:
2729:
2723:
2720:
2718:
2715:
2713:
2710:
2707:
2706:
2703:
2700:
2698:
2694:
2691:
2688:
2687:
2684:
2681:
2677:
2674:
2672:
2669:
2668:
2667:
2664:
2660:
2657:
2655:
2652:
2650:
2647:
2646:
2645:
2642:
2639:
2638:
2636:
2632:
2629:
2625:
2619:
2616:
2614:
2611:
2609:
2606:
2605:
2603:
2599:
2595:
2588:
2583:
2581:
2576:
2574:
2569:
2568:
2565:
2551:
2545:
2540:
2536:
2530:
2525:
2524:
2521:
2512:
2507:
2505:
2500:
2498:
2493:
2492:
2489:
2482:
2478:
2475:
2474:
2463:
2459:
2455:
2451:
2448:(6): 389–97.
2447:
2443:
2437:
2433:
2429:
2424:
2419:
2415:
2411:
2407:
2403:
2399:
2394:
2390:
2386:
2382:
2378:
2373:
2368:
2364:
2360:
2356:
2351:
2347:
2343:
2339:
2335:
2330:
2325:
2321:
2317:
2313:
2308:
2304:
2300:
2295:
2290:
2285:
2280:
2276:
2272:
2268:
2264:
2260:
2255:
2251:
2247:
2242:
2237:
2233:
2229:
2225:
2221:
2217:
2212:
2208:
2204:
2199:
2194:
2189:
2184:
2180:
2176:
2172:
2167:
2163:
2159:
2154:
2149:
2145:
2141:
2140:J. Biol. Chem
2137:
2132:
2128:
2124:
2120:
2116:
2111:
2106:
2102:
2098:
2094:
2089:
2085:
2081:
2076:
2071:
2067:
2063:
2060:(4): 919–26.
2059:
2055:
2051:
2046:
2042:
2038:
2034:
2030:
2025:
2020:
2016:
2012:
2008:
2003:
1999:
1995:
1991:
1987:
1982:
1977:
1973:
1969:
1965:
1960:
1956:
1952:
1947:
1942:
1938:
1934:
1931:(5): 1083–9.
1930:
1926:
1922:
1917:
1913:
1909:
1904:
1899:
1895:
1891:
1887:
1883:
1879:
1874:
1870:
1866:
1861:
1856:
1852:
1848:
1845:(2): 235–44.
1844:
1840:
1836:
1831:
1827:
1823:
1819:
1815:
1811:
1807:
1802:
1798:
1794:
1789:
1784:
1780:
1776:
1772:
1767:
1766:
1753:
1747:
1743:
1736:
1729:
1722:
1716:
1708:
1704:
1699:
1694:
1689:
1684:
1680:
1676:
1672:
1665:
1657:
1653:
1648:
1643:
1639:
1635:
1632:(1): 434–47.
1631:
1627:
1623:
1616:
1608:
1604:
1599:
1594:
1590:
1586:
1583:(5): 2953–9.
1582:
1578:
1574:
1567:
1559:
1555:
1551:
1547:
1543:
1539:
1535:
1531:
1523:
1517:
1516:0-7216-0008-5
1513:
1509:
1503:
1495:
1491:
1486:
1481:
1477:
1473:
1472:J. Biol. Chem
1469:
1462:
1454:
1450:
1446:
1442:
1437:
1432:
1428:
1424:
1420:
1413:
1405:
1399:
1397:
1389:
1388:0-7817-2120-2
1385:
1381:
1375:
1373:
1364:
1360:
1354:
1346:
1342:
1336:
1329:
1325:
1320:
1318:
1316:
1308:
1304:
1299:
1297:
1295:
1290:
1283:
1281:
1277:
1273:
1269:
1265:
1261:
1257:
1253:
1248:
1246:
1242:
1233:
1224:
1222:
1216:
1214:
1209:
1206:
1195:
1193:
1189:
1185:
1183:
1179:
1176:
1172:
1168:
1164:
1154:
1152:
1148:
1144:
1140:
1135:
1133:
1129:
1125:
1121:
1117:
1113:
1101:
1096:
1092:
1088:
1085:
1081:
1074:
1072:
1069:
1065:
1061:
1057:
1054:
1050:
1046:
1039:
1033:
1029:
1026:
1020:
1018:
1014:
1008:
1004:
1001:
997:
990:
988:
984:
978:
974:
971:
965:
963:
959:
953:
949:
946:
944:RefSeq (mRNA)
942:
935:
934:
929:
925:
922:
916:
915:
910:
906:
903:
901:
897:
890:
889:
884:
880:
877:
871:
870:
865:
861:
858:
856:
852:
845:
844:
839:
835:
832:
826:
825:
820:
816:
813:
811:
807:
804:
801:
799:
796:
792:
789:
785:
781:
774:
770:
765:
759:
756:
754:
751:
749:
746:
744:
743:viral process
741:
739:
736:
734:
731:
729:
726:
724:
721:
719:
716:
714:
711:
709:
706:
705:
703:
700:
699:
693:
690:
688:
685:
683:
680:
678:
675:
673:
670:
669:
667:
664:
663:
657:
654:
652:
649:
647:
644:
642:
639:
637:
634:
632:
629:
627:
624:
623:
621:
618:
617:
614:
613:Gene ontology
610:
606:
594:
589:
585:
580:
577:
575:
571:
563:
558:
547:
543:
539:
535:
531:
527:
523:
519:
515:
511:
510:
507:
503:
498:
495:
485:
481:
477:
473:
469:
465:
461:
457:
453:
449:
448:
445:
441:
436:
433:
432:
429:
427:
423:
421:
420:
416:
415:
412:
410:
406:
402:
398:
394:
386:
381:
377:
373:
368:
358:
354:
347:
340:
334:
327:
319:
315:
311:
306:
302:
297:
293:
285:
280:
276:
272:
267:
257:
253:
246:
239:
233:
226:
222:
216:
212:
208:
203:
199:
194:
190:
186:
182:
178:
174:
170:
166:
162:
158:
154:
150:
142:
137:
130:
125:
120:
109:
107:
103:
99:
95:
91:
87:
81:
76:
73:
72:
68:
65:
58:
54:
49:
45:
41:
36:
31:
19:
5911:
5819:Co-receptors
5772:MHC class II
5677:
5110:
4542:
4462:
4440:
4418:
4265:
4228:
4191:
4144:
4114:
4087:
3909:
3815:
3663:
3392:
3218:
3144:
2979:Opsonization
2974:inflammation
2962:Cytotoxicity
2905:
2879:
2869:
2849:C1-inhibitor
2845:
2708:
2689:
2640:
2549:
2534:
2445:
2442:Mol. Immunol
2441:
2405:
2401:
2362:
2358:
2322:(1): 312–5.
2319:
2315:
2266:
2262:
2223:
2219:
2178:
2174:
2143:
2139:
2100:
2096:
2057:
2053:
2014:
2010:
1974:(2): 590–4.
1971:
1967:
1928:
1924:
1888:(1): 55–64.
1885:
1881:
1842:
1838:
1809:
1806:Mol. Immunol
1805:
1778:
1774:
1741:
1735:
1715:cite journal
1678:
1674:
1664:
1629:
1625:
1615:
1580:
1576:
1566:
1533:
1529:
1522:
1507:
1502:
1475:
1471:
1461:
1426:
1422:
1412:
1379:
1362:
1353:
1344:
1335:
1249:
1238:
1217:
1210:
1201:
1186:
1160:
1157:Interactions
1136:
1123:
1119:
1115:
1111:
1110:
1035:
1013:NP_001006659
1010:
987:NM_001368765
980:
958:NM_001006658
955:
931:
912:
886:
867:
841:
822:
802:
797:
424:
417:
383:194,859,024
370:194,819,119
282:207,489,895
269:207,454,230
144:External IDs
83:
5767:MHC class I
5663:Co-receptor
5526:Epsilon (ε)
5517:Fc receptor
5133:plasma cell
5116:CD23/FcεRII
2517:PDB gallery
2402:J. Exp. Med
2220:J. Exp. Med
1925:J. Exp. Med
1882:J. Exp. Med
626:DNA binding
122:Identifiers
6086:Categories
5671:stimulate:
5088:CD10/CALLA
5084:Pre-B cell
5060:by lineage
3027:(see also
2839:Inhibitors
2359:J. Immunol
2316:J. Immunol
2097:J. Immunol
2011:J. Immunol
1968:J. Immunol
1681:(1): 115.
1626:J. Immunol
1577:J. Immunol
1423:J. Immunol
1330:, May 2017
1309:, May 2017
1286:References
1260:neoplastic
462:lymph node
428:(ortholog)
165:HomoloGene
5610:Secretory
5555:Gamma (γ)
5450:Stem cell
5241:CD56/NCAM
2972:Inducing
1274:and some
1175:opsonized
1163:interacts
1017:NP_001868
983:NM_007758
962:NM_001877
788:Orthologs
532:spermatid
173:GeneCards
5958:KIR2DL5B
5953:KIR2DL5A
5695:inhibit:
5578:Neonatal
5111:CD21/CR2
5099:mature:
5067:Lymphoid
3021:Proteins
2964:(by MAC)
2955:Function
2883:Factor H
2863:Factor I
2717:Factor D
2712:Factor B
2601:Pathways
2389:42434103
2346:28146101
2127:20445833
2041:22824326
1998:24059423
1707:31269981
1656:23733878
1607:18713965
1558:20793968
1453:23655762
1326:–
1305:–
1198:Isoforms
1178:antigens
1084:Wikidata
767:Sources:
677:membrane
482:testicle
458:appendix
6003:KIR3DS1
5998:KIR3DL3
5993:KIR3DL2
5988:KIR3DL1
5983:KIR2DS5
5978:KIR2DS4
5973:KIR2DS3
5968:KIR2DS2
5963:KIR2DS1
5948:KIR2DL4
5943:KIR2DL3
5938:KIR2DL2
5933:KIR2DL1
5877:ζ-chain
5754:Ligands
5745:T cells
5638:B cells
5573:FcγRIII
5362:CFU-Meg
5296:Myeloid
5228:NK cell
4829:301–350
4623:251–300
4575:CD240CE
4372:201–250
4056:151–200
3779:101–150
2462:7753047
2432:7690834
2423:2191213
2381:7515913
2338:3782802
2303:3016712
2271:Bibcode
2250:2832506
2241:2188894
2207:2827171
2162:2563370
2119:2528587
2084:1849076
2033:1831222
1990:1830068
1955:1708808
1946:2118840
1912:1702139
1903:2118751
1869:1424280
1860:1554594
1826:1323059
1797:2161885
1698:6610797
1647:3707406
1598:3366432
1494:9804823
1445:1383329
1328:Ensembl
1307:Ensembl
1151:B cells
1128:protein
900:UniProt
855:Ensembl
794:Species
773:QuickGO
403:pattern
129:Aliases
6071:LILRB5
6066:LILRB4
6061:LILRB3
6056:LILRB2
6051:LILRB1
6046:LILRA6
6041:LILRA5
6036:LILRA4
6031:LILRA3
6026:LILRA2
6021:LILRA1
5601:Fcα/μR
5568:FcγRII
5540:FcεRII
5305:CFU-GM
5159:T cell
5076:B cell
4836:CD300A
4795:CDw293
4580:CD240D
4441:CD213a
4419:CDw210
4384:CD202b
4358:CDw199
4353:CDw198
4007:CD140b
3439:51–100
2731:Middle
2483:(MeSH)
2460:
2430:
2420:
2387:
2379:
2344:
2336:
2301:
2294:386344
2291:
2248:
2238:
2205:
2198:299719
2195:
2160:
2125:
2117:
2082:
2075:452735
2072:
2054:EMBO J
2039:
2031:
1996:
1988:
1953:
1943:
1910:
1900:
1867:
1857:
1824:
1795:
1748:
1705:
1695:
1654:
1644:
1605:
1595:
1556:
1550:181330
1548:
1514:
1492:
1451:
1443:
1386:
1122:, and
1070:search
1068:PubMed
933:P19070
914:P20023
810:Entrez
574:BioGPS
548:embryo
540:embryo
512:spleen
486:rectum
474:tonsil
454:spleen
261:1q32.2
153:120650
5596:FcαRI
5563:FcγRI
5534:FcεRI
5398:CFU-E
5318:CD11c
5142:CD138
5121:CD127
5093:CD79A
5016:CD350
5011:CD349
5006:CD344
5001:CD340
4996:CD339
4991:CD338
4986:CD337
4981:CD336
4976:CD335
4971:CD334
4966:CD333
4961:CD332
4956:CD331
4951:CD329
4946:CD328
4941:CD327
4936:CD326
4931:CD325
4926:CD324
4921:CD322
4916:CD321
4911:CD320
4906:CD318
4901:CD317
4896:CD316
4891:CD315
4886:CD314
4881:CD312
4876:CD309
4871:CD307
4866:CD306
4861:CD305
4856:CD304
4851:CD303
4846:CD302
4841:CD301
4820:CD299
4815:CD298
4810:CD297
4805:CD295
4800:CD294
4790:CD292
4785:CD290
4780:CD289
4775:CD288
4770:CD286
4765:CD284
4760:CD283
4755:CD282
4750:CD281
4745:CD280
4740:CD279
4735:CD278
4730:CD276
4725:CD275
4720:CD274
4715:CD273
4710:CD272
4705:CD271
4700:CD269
4695:CD268
4690:CD267
4685:CD266
4680:CD265
4675:CD264
4670:CD263
4665:CD262
4660:CD261
4655:CD258
4650:CD257
4645:CD256
4640:CD254
4635:CD253
4630:CD252
4614:CD249
4609:CD248
4605:CD247
4600:CD246
4595:CD244
4590:CD243
4585:CD241
4570:CD239
4565:CD238
4560:CD236
4543:CD235
4538:CD234
4533:CD233
4528:CD230
4523:CD229
4518:CD228
4513:CD227
4508:CD226
4503:CD225
4498:CD224
4493:CD223
4488:CD222
4483:CD221
4478:CD220
4463:CD218
4458:CD217
4436:CD212
4414:CD209
4409:CD208
4404:CD207
4399:CD206
4394:CD205
4389:CD204
4379:CD201
4363:CD200
4348:CD197
4343:CD196
4338:CD195
4333:CD194
4328:CD193
4323:CD192
4318:CD191
4313:CD186
4308:CD185
4303:CD184
4298:CD183
4293:CD182
4288:CD181
4283:CD180
4266:CD179
4261:CD178
4256:CD177
4251:CD174
4229:CD172
4224:CD171
4219:CD170
4214:CD169
4209:CD168
4192:CD167
4187:CD166
4182:CD164
4177:CD163
4172:CD162
4167:CD161
4162:CD160
4145:CD159
4115:CD158
4110:CD157
4088:CD156
4083:CD155
4078:CD154
4073:CD153
4068:CD152
4063:CD151
4047:CD150
4042:CD148
4037:CD147
4032:CD146
4027:CD144
4022:CD143
4017:CD142
4012:CD141
4002:CD138
3997:CD137
3992:CD136
3987:CD135
3982:CD134
3977:CD133
3972:CD132
3967:CD131
3962:CD130
3957:CD129
3952:CD127
3947:CD126
3942:CD125
3937:CD124
3932:CD123
3927:CD122
3910:CD121
3893:CD120
3888:CD119
3883:CD118
3878:CD117
3873:CD116
3868:CD115
3863:CD114
3858:CD113
3853:CD112
3848:CD111
3843:CD110
3838:CD109
3833:CD108
3816:CD107
3811:CD106
3806:CD105
3801:CD104
3796:CD103
3791:CD102
3786:CD101
3770:CD100
2925:CD11c
2921:CD11b
2697:MASP2
2693:MASP1
2634:Early
2385:S2CID
2342:S2CID
2123:S2CID
2037:S2CID
1994:S2CID
1554:S2CID
1449:S2CID
1165:with
843:12902
803:Mouse
798:Human
769:Amigo
520:blood
426:Mouse
419:Human
366:Start
301:Mouse
265:Start
198:Human
169:55611
161:88489
5912:see
5885:TCRζ
5883:and
5881:CD3ζ
5872:CD3ε
5867:CD3δ
5862:CD3γ
5835:CD8β
5833:and
5831:CD8α
5809:TRG@
5804:TRD@
5799:TRB@
5794:TRA@
5730:CD79
5726:Ig-β
5722:Ig-α
5702:CD22
5686:CD81
5682:CD19
5678:CD21
5458:CD34
5436:CD33
5431:CD13
5411:CD71
5406:CD36
5388:CD61
5384:CD41
5379:CD42
5374:CD36
5370:CD34
5343:CD68
5338:CD64
5333:CD31
5328:CD15
5323:CD14
5246:CD57
5236:CD16
5218:CD28
5213:CD27
5208:CD26
5203:CD18
5198:CD13
5151:T/NK
5137:CD38
5126:CD40
5106:CD20
5101:CD19
3765:CD99
3760:CD98
3755:CD97
3750:CD96
3745:CD95
3740:CD94
3735:CD93
3730:CD92
3726:CD91
3721:CD90
3716:CD89
3711:CD88
3706:CD87
3701:CD86
3664:CD85
3659:CD84
3654:CD83
3649:CD82
3644:CD81
3639:CD80
3622:CD79
3617:CD78
3612:CD74
3607:CD73
3602:CD72
3597:CD71
3592:CD70
3587:CD69
3582:CD68
3545:CD66
3523:CD64
3518:CD63
3496:CD62
3491:CD61
3486:CD59
3481:CD58
3476:CD57
3471:CD56
3466:CD55
3461:CD54
3456:CD53
3451:CD52
3446:CD51
3430:CD50
3393:CD49
3388:CD48
3383:CD47
3378:CD46
3373:CD45
3368:CD44
3363:CD43
3336:CD42
3331:CD41
3326:CD40
3321:CD39
3316:CD38
3311:CD37
3306:CD36
3301:CD35
3296:CD34
3291:CD33
3274:CD32
3269:CD31
3264:CD30
3259:CD29
3254:CD28
3249:CD27
3244:CD26
3239:CD25
3234:CD24
3229:CD23
3224:CD22
3219:CD21
3214:CD20
3209:CD19
3204:CD18
3187:CD16
3182:CD15
3177:CD14
3172:CD13
3145:CD11
3140:CD10
3037:1–50
2929:CD18
2873:C4BP
2858:CD59
2846:CLA:
2792:Late
2752:iC3b
2550:1ly2
2535:1ghq
2458:PMID
2428:PMID
2377:PMID
2334:PMID
2299:PMID
2246:PMID
2203:PMID
2158:PMID
2115:PMID
2080:PMID
2029:PMID
1986:PMID
1951:PMID
1908:PMID
1865:PMID
1822:PMID
1793:PMID
1746:ISBN
1721:link
1703:PMID
1652:PMID
1603:PMID
1546:PMID
1512:ISBN
1490:PMID
1441:PMID
1384:ISBN
1171:CD81
1167:CD19
1143:iC3b
1132:gene
1124:CD21
824:1380
409:Bgee
357:Band
318:Chr.
256:Band
215:Chr.
149:OMIM
106:3OED
102:2GSX
98:1W2S
94:1W2R
90:1LY2
86:1GHQ
67:RCSB
64:PDBe
18:CD21
5857:CD3
5841:CD4
5827:CD8
5790:TCR
5762:MHC
5653:BCR
5542:is
5353:MEP
5282:CD5
5275:All
5262:CD2
5255:All
5193:CD8
5188:CD4
5183:CD1
5176:CD7
5171:CD3
3135:CD9
3123:CD8
3118:CD7
3113:CD6
3108:CD5
3103:CD4
3081:CD3
3076:CD2
3049:a-c
3044:CD1
2944:C5a
2939:C3a
2916:CR4
2911:CR3
2906:CR2
2901:CR1
2870:CL:
2804:C5b
2799:MAC
2769:C5b
2764:C5a
2748:C3b
2743:C3a
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