Knowledge

CD146

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CD146 has been demonstrated to appear on a small subset of T and B lymphocytes in the peripheral blood of healthy individuals. The CD146+ T cells display an immunophenotype consistent with effector memory cells and have a distinct gene profile from the CD146- T cells. CD146 T cells have been shown by
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cells. MCAM expression is positively correlated to melanoma progression at which the expression of MCAM is highest in metastatic melanoma cells. The significance of MCAM upregulation is evident in melanoma cells cultured in 3D skin reconstruct in which MCAM facilitates the migration of melanoma into
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Two isoforms exist (MCAM long (MCAM-1), and MCAM short, or MCAM-s) which differ in the length of their cytoplasmic domain. Activation of these isoforms seems to produce functional differences as well. Natural killer cells transfected with MCAM-1 demonstrate decreased rolling velocity and increased
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MCAM functions as a receptor for laminin alpha 4, a matrix molecule that is broadly expressed within the vascular wall. Accordingly, MCAM is highly expressed by cells that are components of the blood vessel wall, including vascular endothelial cells, smooth muscle cells and pericytes. Its function
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CD146 has been seen as a marker for mesenchymal stem cells isolated from multiple adult and fetal organs, and its expression may be linked to multipotency; mesenchymal stem cells with greater differentiation potential express higher levels of CD146 on the cell surface.
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expression on the surface of melanoma cells. Melanoma cells with functional E-cadherin on the surface can only exclusively grow in the epidermis as keratinocytes frequently downregulate the expression of MCAM on melanoma cells.
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Malyszko J, Malyszko JS, Kozminski P, Pawlak K, Mysliwiec M (July 2008). "Adipokines, linking adipocytes and vascular function in hemodialyzed patients, may also be possibly related to CD146, a novel adhesion molecule".
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cell adhesion to an endothelial cell monolayer and increased microvilli formation while cells transfected with MCAM-s showed no change in adhesion characteristics. Since these characteristics are important in
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Zheng C, Qiu Y, Zeng Q, Zhang Y, Lu D, Yang D, et al. (November 2009). "Endothelial CD146 is required for in vitro tumor-induced angiogenesis: the role of a disulfide bond in signaling and dimerization".
1513:"Dual role of melanoma cell adhesion molecule (MCAM)/CD146 in lymphocyte endothelium interaction: MCAM/CD146 promotes rolling via microvilli induction in lymphocyte and is an endothelial adhesion receptor" 2220:
Saito O, Saito T, Okuda K, Okuda K, Kotoda A, Akimoto T, et al. (February 2008). "Serum adiponectin and markers of endothelial injury in hemodialysis patients with arteriosclerosis obliterans".
877:, it consists of five Ig domains, a transmembrane domain, and a cytoplasmic region. It is expressed on chicken embryonic spleen and thymus, activated human T cells, endothelial progenitors such as 1889:
Samuels TL, Handler E, Syring ML, Pajewski NM, Blumin JH, Kerschner JE, Johnston N (September 2008). "Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux".
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Ouhtit A, Gaur RL, Abd Elmageed ZY, Fernando A, Thouta R, Trappey AK, et al. (April 2009). "Towards understanding the mode of action of the multifaceted cell adhesion receptor CD146".
2000:"Crosstalk between protease-activated receptor 1 and platelet-activating factor receptor regulates melanoma cell adhesion molecule (MCAM/MUC18) expression and melanoma metastasis" 2043:
Chen W, Zhang HL, Jiang YG, Li JH, Liu BL, Sun MY (February 2009). "Inhibition of CD146 gene expression via RNA interference reduces in vitro perineural invasion on ACC-M cell".
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Fritzsche FR, Wassermann K, Rabien A, Schicktanz H, Dankof A, Loening SA, et al. (August 2008). "CD146 protein in prostate cancer: revisited with two different antibodies".
1297:"Multipotent mesenchymal stromal cells obtained from diverse human tissues share functional properties and gene-expression profile with CD146+ perivascular cells and fibroblasts" 1805:"In vitro high-capacity assay to quantify the clonal heterogeneity in trilineage potential of mesenchymal stem cells reveals a complex hierarchy of lineage commitment" 1338:"In vitro high-capacity assay to quantify the clonal heterogeneity in trilineage potential of mesenchymal stem cells reveals a complex hierarchy of lineage commitment" 3176: 1591:"A subset of host B lymphocytes controls melanoma metastasis through a melanoma cell adhesion molecule/MUC18-dependent interaction: evidence from mice and humans" 2315: 1762:"Identification of MCAM/CD146 as the target antigen of a human monoclonal antibody that recognizes both epithelioid and sarcomatoid types of mesothelioma" 1739:
Wang N, Fan Y, Ni P, Wang F, Gao X, Xue Q, Tang L (2008). "High glucose effect on the role of CD146 in human proximal tubular epithelial cells in vitro".
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is still poorly understood, but evidence points to it being part of the endothelial junction associated with the actin cytoskeleton. A member of the
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Johnson JP, RothbΓ€cher U, Sers C (October 1993). "The progression associated antigen MUC18: a unique member of the immunoglobulin supergene family".
3166: 2293: 1030: 1012: 1156:"CD146 (Mel-CAM), an adhesion marker of endothelial cells, is a novel marker of lymphocyte subset activation in normal peripheral blood" 775: 3146: 1564: 1547: 1248:"MCAM-expressing CD4(+) T cells in peripheral blood secrete IL-17A and are significantly elevated in inflammatory autoimmune diseases" 4008: 2332: 2308: 2275: 2074:"CD146 expression is associated with a poor prognosis in human breast tumors and with enhanced motility in breast cancer cell lines" 782: 4501: 3739: 3727: 3505: 1197:"A unique population of effector memory lymphocytes identified by CD146 having a distinct immunophenotypic and genomic profile" 4891: 4345: 3791: 3786: 3732: 3512: 1050:"Assignment of the human melanoma cell adhesion molecule gene (MCAM) to chromosome 11 band q23.3 by radiation hybrid mapping" 995: 3245: 3171: 2301: 2281: 4274: 4269: 4264: 4259: 3186: 974: 4870: 4239: 1049: 241: 4373: 4338: 3475: 4580: 4400: 4043: 3537: 3223: 999: 978: 218: 3682: 3218: 612: 2323: 4390: 4179: 3651: 3646: 3591: 3325: 2774: 140: 115: 2119:"Co-expression of two perivascular cell markers isolates mesenchymal stem-like cells from human endometrium" 593: 3873: 3596: 57: 3191: 857:
currently used as a marker for endothelial cell lineage. In humans, the CD146 protein is encoded by the
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Melnikova VO, Balasubramanian K, Villares GJ, Dobroff AS, Zigler M, Wang H, et al. (October 2009).
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Tripodo C, Di Bernardo A, Ternullo MP, Guarnotta C, Porcasi R, Ingrao S, et al. (January 2009).
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Elshal MF, Khan SS, Raghavachari N, Takahashi Y, Barb J, Bailey JJ, et al. (November 2007).
894: 1848:"CD146(+) bone marrow osteoprogenitors increase in the advanced stages of primary myelofibrosis" 754: 733: 703: 682: 4365: 3260: 3255: 3250: 3240: 2547: 2475: 882: 854: 1926:
Bardin N, Blot-Chabaud M, Despoix N, Kebir A, Harhouri K, Arsanto JP, et al. (May 2009).
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Covas DT, Panepucci RA, Fontes AM, Silva WA, Orellana MD, Freitas MC, et al. (May 2008).
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Staquicini FI, Tandle A, Libutti SK, Sun J, Zigler M, Bar-Eli M, et al. (October 2008).
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Russell KC, Phinney DG, Lacey MR, Barrilleaux BL, Meyertholen KE, O'Connor KC (April 2010).
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Russell KC, Phinney DG, Lacey MR, Barrilleaux BL, Meyertholen KE, O'Connor KC (April 2010).
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Barbe L, Lundberg E, Oksvold P, Stenius A, Lewin E, BjΓΆrling E, et al. (March 2008).
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Zabouo G, Imbert AM, Jacquemier J, Finetti P, Moreau T, Esterni B, et al. (2009).
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Flanagan K, Fitzgerald K, Baker J, Regnstrom K, Gardai S, Bard F, et al. (2012).
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Dagur PK, Biancotto A, Wei L, Sen HN, Yao M, Strober W, et al. (December 2011).
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Bidlingmaier S, He J, Wang Y, An F, Feng J, Barbone D, et al. (February 2009).
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Guezguez B, Vigneron P, Lamerant N, Kieda C, Jaffredo T, Dunon D (November 2007).
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National Center for Biotechnology Information, U.S. National Library of Medicine
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National Center for Biotechnology Information, U.S. National Library of Medicine
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10.1002/(SICI)1096-9896(199909)189:1<4::AID-PATH332>3.0.CO;2-P
822: 817: 4721: 4654: 4614: 4604: 4229: 3878: 3656: 3631: 3330: 2952: 2878: 2352: 1928:"CD146 and its soluble form regulate monocyte transendothelial migration" 950: 886: 657: 638: 1687: 1670: 4827: 4798: 4793: 4788: 4711: 4632: 4159: 3883: 3564: 3305: 3181: 2814: 2809: 2804: 2659: 2443: 1997: 1671:"Cellular adhesion pathways and metastatic potential of human melanoma" 1470:"CD146, from a melanoma cell adhesion molecule to a signaling receptor" 921: 878: 226: 123: 73: 1154:
Elshal MF, Khan SS, Takahashi Y, Solomon MA, McCoy JP (October 2005).
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do not express MCAM and the expression of MCAM is first found in
624: 579: 48:, CD146, MUC18, melanoma cell adhesion molecule, HEMETCAM, MelCAM 1094: 897:, MCAM-1 may be an important part of the inflammatory response. 61: 4690: 4561: 4451: 4414: 4404: 4194: 4154: 4139: 4123: 4118: 4098: 4093: 4028: 3836: 3806: 3770: 3761: 3574: 3542: 3406: 3401: 3371: 3350: 3310: 3270: 3136: 3114: 3073: 2997: 2992: 2987: 2982: 2977: 2972: 2841: 2836: 2831: 2779: 2764: 2634: 2624: 2587: 2582: 2500: 2495: 2151: 1194: 934: 790: 534: 4360: 1925: 1802: 1384: 1335: 4842: 4838: 4766: 4756: 4751: 4746: 4741: 4736: 4685: 4565: 4547: 4543: 4533: 4519: 4505: 4481: 4476: 4471: 4466: 4461: 4456: 4439: 4434: 4408: 4319: 4294: 4214: 4209: 4199: 4189: 4174: 4169: 4164: 4149: 4103: 4088: 4053: 4038: 4033: 4023: 3943: 3938: 3933: 3912: 3908: 3898: 3811: 3712: 3707: 3666: 3616: 3611: 3606: 3601: 3586: 3579: 3559: 3547: 3490: 3485: 3480: 3470: 3465: 3458: 3396: 3386: 3381: 3376: 3366: 3345: 3300: 3295: 3290: 3285: 3280: 3235: 3230: 3196: 3161: 3156: 3151: 3141: 3129: 3124: 3104: 3099: 3094: 3089: 3043: 2935: 2930: 2749: 2733: 2726: 2721: 2716: 2711: 2706: 2701: 2676: 2654: 2649: 2542: 2468: 2463: 2453: 2071: 1510: 925: 2193:
The International Journal of Biochemistry & Cell Biology
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Wang Z, Xu Q, Zhang N, Du X, Xu G, Yan X (August 2020).
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Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
1548:"The role of CD146 (Mel-CAM) in biology and pathology" 1631: 482: 2219: 1759: 1422: 1245: 949:. The control by keratinocytes are only achieved by 1932:Arteriosclerosis, Thrombosis, and Vascular Biology 1423:Haass NK, Smalley KS, Li L, Herlyn M (June 2005). 991: 989: 987: 970: 968: 966: 2189: 1891:The Annals of Otology, Rhinology, and Laryngology 264: 163: 4883: 2042: 1668: 984: 963: 16:Protein-coding gene in the species Homo sapiens 996:GRCm38: Ensembl release 89: ENSMUSG00000032135 4346: 2309: 2116: 1738: 1467: 1378: 1329: 1288: 1047: 1239: 1188: 1147: 1041: 975:GRCh38: Ensembl release 89: ENSG00000076706 4353: 4339: 2316: 2302: 2155:Clinical and Applied Thrombosis/Hemostasis 2333:list of human clusters of differentiation 2267:at the U.S. National Library of Medicine 2134: 2099: 2089: 2025: 2015: 1943: 1871: 1820: 1785: 1721: 1686: 1614: 1563: 1528: 1493: 1440: 1353: 1312: 1271: 1222: 1212: 1171: 1130: 1120: 885:, and strongly expressed on blood vessel 2045:Journal of Oral Pathology & Medicine 1474:Signal Transduction and Targeted Therapy 2117:Schwab KE, Gargett CE (November 2007). 901:Dagur and colleagues to produce IL-17. 4884: 908: 4334: 2297: 1669:McGary EC, Lev DC, Bar-Eli M (2002). 1418: 1416: 269: 230: 225: 168: 127: 122: 2222:Clinical and Experimental Nephrology 1545: 2004:The Journal of Biological Chemistry 1710:Molecular & Cellular Proteomics 945:that inhibit penetrance beyond the 13: 1460: 1413: 14: 4903: 2258: 2057:10.1111/j.1600-0714.2008.00706.x 1646:10.1097/00008390-199310000-00006 1442:10.1111/j.1600-0749.2005.00235.x 253: 246: 240: 217: 152: 145: 139: 114: 851:cell surface glycoprotein MUC18 843:melanoma cell adhesion molecule 1088: 1054:Cytogenetics and Cell Genetics 1023: 1005: 471:More reference expression data 1: 1778:10.1158/0008-5472.CAN-08-1363 1607:10.1158/0008-5472.CAN-08-1242 1048:Kuske MD, Johnson JP (1999). 957: 421:tunica media of zone of aorta 238: 137: 4892:Genes on human chromosome 11 2205:10.1016/j.biocel.2009.03.014 1675:Cancer Biology & Therapy 1530:10.4049/jimmunol.179.10.6673 1314:10.1016/j.exphem.2007.12.015 1122:10.1371/journal.pone.0040443 7: 2329:clusters of differentiation 1399:10.1016/j.bbcan.2009.01.002 867: 395:subcutaneous adipose tissue 10: 4908: 4819:Lymphocyte homing receptor 2286:gene details page in the 1945:10.1161/ATVBAHA.108.183251 1903:10.1177/000348940811700911 1723:10.1074/mcp.M700325-MCP200 1546:Shih IM (September 1999). 1486:10.1038/s41392-020-00259-8 1264:10.1016/j.jaut.2011.09.003 1173:10.1182/blood-2005-06-2307 875:Immunoglobulin superfamily 839:cluster of differentiation 776:Chr 11: 119.31 – 119.32 Mb 437:tunica adventitia of aorta 4811: 4779: 4704: 4676: 4623: 4597: 4588: 4579: 4492: 4381: 4372: 4132: 3926: 3675: 3359: 3082: 2742: 2340: 2234:10.1007/s10157-007-0012-7 1975:10.1080/00313020802197996 1031:"Mouse PubMed Reference:" 1013:"Human PubMed Reference:" 821: 816: 812: 805: 789: 770: 751: 747: 730: 726: 719: 700: 696: 679: 675: 668: 655: 651: 636: 632: 623: 610: 606: 591: 587: 578: 565: 561: 546: 542: 533: 518: 511: 507: 495: 490: 481: 468: 417: 408: 387:Descending thoracic aorta 355: 346: 316: 308: 304: 287: 274: 237: 216: 207: 203: 186: 173: 136: 113: 104: 100: 55: 52: 42: 35: 30: 26: 21: 4851:Carcinoembryonic antigen 4705:Unconventional/ungrouped 2269:Medical Subject Headings 2167:10.1177/1076029607305083 1552:The Journal of Pathology 4366:cell adhesion molecules 2017:10.1074/jbc.M109.042150 1301:Experimental Hematology 1252:Journal of Autoimmunity 895:leukocyte extravasation 841:146) also known as the 783:Chr 9: 44.05 – 44.05 Mb 2078:Breast Cancer Research 1864:10.3324/haematol.13598 1214:10.1186/1471-2172-8-29 883:mesenchymal stem cells 855:cell adhesion molecule 4558:Glycoprotein IIb/IIIa 2136:10.1093/humrep/dem265 1741:Journal of Nephrology 1517:Journal of Immunology 1429:Pigment Cell Research 367:right coronary artery 130:Chromosome 11 (human) 4530:Macrophage-1 antigen 4516:Integrin alphaXbeta2 2280:genome location and 453:facial motor nucleus 441:white adipose tissue 375:left coronary artery 232:Chromosome 9 (mouse) 4395:Myelin protein zero 4374:Calcium-independent 2288:UCSC Genome Browser 1688:10.4161/cbt.1.5.158 1113:2012PLoSO...740443F 909:Relevance in cancer 889:and smooth muscle. 2123:Human Reproduction 613:ENSMUSG00000032135 4879: 4878: 4807: 4806: 4775: 4774: 4581:Calcium-dependent 4575: 4574: 4362:Membrane proteins 4328: 4327: 1634:Melanoma Research 1066:10.1159/000015439 947:basement membrane 832: 831: 828: 827: 801: 800: 766: 765: 741: 740: 715: 714: 690: 689: 664: 663: 645: 644: 619: 618: 600: 599: 574: 573: 555: 554: 503: 502: 499: 498: 477: 476: 464: 463: 425:lactiferous gland 402: 401: 300: 299: 199: 198: 4899: 4595: 4594: 4586: 4585: 4379: 4378: 4355: 4348: 4341: 4332: 4331: 2318: 2311: 2304: 2295: 2294: 2253: 2216: 2186: 2148: 2138: 2113: 2103: 2093: 2068: 2039: 2029: 2019: 2010:(42): 28845–55. 1994: 1957: 1947: 1922: 1885: 1875: 1842: 1824: 1822:10.1002/stem.312 1799: 1789: 1756: 1735: 1725: 1700: 1690: 1665: 1628: 1618: 1585: 1567: 1542: 1532: 1507: 1497: 1455: 1454: 1444: 1420: 1411: 1410: 1382: 1376: 1375: 1357: 1355:10.1002/stem.312 1333: 1327: 1326: 1316: 1292: 1286: 1285: 1275: 1243: 1237: 1236: 1226: 1216: 1192: 1186: 1185: 1175: 1151: 1145: 1144: 1134: 1124: 1092: 1086: 1085: 1045: 1039: 1038: 1027: 1021: 1020: 1009: 1003: 993: 982: 972: 814: 813: 785: 778: 761: 745: 744: 736: 724: 723: 720:RefSeq (protein) 710: 694: 693: 685: 673: 672: 649: 648: 630: 629: 604: 603: 585: 584: 559: 558: 540: 539: 509: 508: 488: 487: 473: 413: 411:Top expressed in 406: 405: 359:popliteal artery 351: 349:Top expressed in 344: 343: 323: 322: 306: 305: 296: 283: 272: 257: 250: 244: 233: 221: 205: 204: 195: 182: 171: 156: 149: 143: 132: 118: 102: 101: 96: 94:MCAM - orthologs 47: 40: 19: 18: 4907: 4906: 4902: 4901: 4900: 4898: 4897: 4896: 4882: 4881: 4880: 4875: 4803: 4771: 4700: 4672: 4619: 4571: 4488: 4368: 4359: 4329: 4324: 4128: 3922: 3671: 3355: 3078: 2738: 2336: 2322: 2261: 2256: 2199:(11): 2163–72. 2129:(11): 2903–11. 2091:10.1186/bcr2215 1766:Cancer Research 1601:(20): 8419–28. 1595:Cancer Research 1523:(10): 6673–85. 1463: 1461:Further reading 1458: 1421: 1414: 1383: 1379: 1334: 1330: 1293: 1289: 1244: 1240: 1193: 1189: 1152: 1148: 1093: 1089: 1046: 1042: 1029: 1028: 1024: 1011: 1010: 1006: 994: 985: 973: 964: 960: 911: 870: 823:View/Edit Mouse 818:View/Edit Human 781: 774: 771:Location (UCSC) 757: 753: 732: 706: 702: 681: 594:ENSG00000076706 469: 460: 457:right lung lobe 455: 451: 447: 445:ascending aorta 443: 439: 435: 431: 427: 423: 409: 398: 393: 389: 385: 383:ascending aorta 381: 377: 373: 369: 365: 363:tibial arteries 361: 347: 291: 278: 270: 260: 259: 258: 251: 231: 208:Gene location ( 190: 177: 169: 159: 158: 157: 150: 128: 105:Gene location ( 56: 43: 36: 17: 12: 11: 5: 4905: 4895: 4894: 4877: 4876: 4874: 4873: 4868: 4863: 4858: 4853: 4847: 4846: 4830: 4825: 4815: 4813: 4809: 4808: 4805: 4804: 4802: 4801: 4796: 4791: 4785: 4783: 4777: 4776: 4773: 4772: 4770: 4769: 4764: 4759: 4754: 4749: 4744: 4739: 4734: 4729: 4724: 4719: 4714: 4708: 4706: 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3871: 3866: 3861: 3860: 3859: 3854: 3844: 3839: 3834: 3829: 3824: 3819: 3814: 3809: 3804: 3799: 3794: 3789: 3784: 3779: 3773: 3764: 3759: 3758: 3757: 3752: 3742: 3737: 3736: 3735: 3730: 3720: 3715: 3710: 3705: 3700: 3695: 3690: 3685: 3679: 3677: 3673: 3672: 3670: 3669: 3664: 3659: 3654: 3649: 3644: 3639: 3634: 3629: 3624: 3619: 3614: 3609: 3604: 3599: 3594: 3589: 3584: 3583: 3582: 3577: 3567: 3562: 3557: 3552: 3551: 3550: 3545: 3540: 3530: 3525: 3520: 3515: 3510: 3509: 3508: 3503: 3493: 3488: 3483: 3478: 3473: 3468: 3463: 3462: 3461: 3456: 3446: 3440: 3435: 3430: 3425: 3416: 3411: 3410: 3409: 3404: 3399: 3389: 3384: 3379: 3374: 3369: 3363: 3361: 3357: 3356: 3354: 3353: 3348: 3343: 3338: 3333: 3328: 3323: 3318: 3313: 3308: 3303: 3298: 3293: 3288: 3283: 3278: 3273: 3268: 3263: 3258: 3253: 3248: 3243: 3238: 3233: 3228: 3227: 3226: 3221: 3211: 3210: 3209: 3204: 3194: 3189: 3184: 3179: 3174: 3169: 3164: 3159: 3154: 3149: 3144: 3139: 3134: 3133: 3132: 3127: 3117: 3112: 3107: 3102: 3097: 3092: 3086: 3084: 3080: 3079: 3077: 3076: 3071: 3066: 3061: 3056: 3051: 3046: 3041: 3036: 3027: 3022: 3017: 3012: 3007: 3002: 3001: 3000: 2995: 2990: 2985: 2980: 2975: 2965: 2960: 2955: 2950: 2945: 2940: 2939: 2938: 2933: 2923: 2918: 2913: 2908: 2903: 2898: 2893: 2888: 2883: 2882: 2881: 2876: 2871: 2866: 2861: 2856: 2846: 2845: 2844: 2839: 2834: 2824: 2819: 2818: 2817: 2812: 2807: 2797: 2792: 2787: 2782: 2777: 2772: 2767: 2762: 2757: 2752: 2746: 2744: 2740: 2739: 2737: 2736: 2731: 2730: 2729: 2724: 2719: 2714: 2709: 2704: 2694: 2689: 2684: 2679: 2674: 2669: 2664: 2663: 2662: 2657: 2652: 2647: 2637: 2632: 2627: 2622: 2617: 2612: 2607: 2602: 2597: 2592: 2591: 2590: 2585: 2575: 2570: 2565: 2560: 2555: 2550: 2545: 2540: 2535: 2530: 2525: 2520: 2515: 2510: 2505: 2504: 2503: 2498: 2488: 2483: 2478: 2473: 2472: 2471: 2466: 2461: 2456: 2446: 2441: 2436: 2435: 2434: 2424: 2419: 2414: 2409: 2404: 2403: 2402: 2397: 2392: 2382: 2377: 2376: 2375: 2370: 2365: 2360: 2355: 2344: 2342: 2338: 2337: 2321: 2320: 2313: 2306: 2298: 2292: 2291: 2272: 2260: 2259:External links 2257: 2255: 2254: 2217: 2187: 2149: 2114: 2069: 2051:(2): 198–205. 2040: 1995: 1958: 1923: 1886: 1843: 1800: 1757: 1736: 1716:(3): 499–508. 1701: 1666: 1629: 1586: 1543: 1508: 1464: 1462: 1459: 1457: 1456: 1412: 1377: 1328: 1287: 1238: 1201:BMC Immunology 1187: 1146: 1087: 1040: 1022: 1004: 983: 961: 959: 956: 913:MCAM inhibits 910: 907: 869: 866: 853:, is a 113kDa 830: 829: 826: 825: 820: 810: 809: 803: 802: 799: 798: 796: 794: 787: 786: 779: 772: 768: 767: 764: 763: 749: 748: 742: 739: 738: 728: 727: 721: 717: 716: 713: 712: 698: 697: 691: 688: 687: 677: 676: 670: 666: 665: 662: 661: 653: 652: 646: 643: 642: 634: 633: 627: 621: 620: 617: 616: 608: 607: 601: 598: 597: 589: 588: 582: 576: 575: 572: 571: 563: 562: 556: 553: 552: 544: 543: 537: 531: 530: 525: 520: 516: 515: 505: 504: 501: 500: 497: 496: 493: 492: 485: 479: 478: 475: 474: 466: 465: 462: 461: 459: 458: 454: 450: 446: 442: 438: 434: 430: 429:left lung lobe 426: 422: 418: 415: 414: 403: 400: 399: 397: 396: 392: 391:gastric mucosa 388: 384: 380: 379:thoracic aorta 376: 372: 371:saphenous vein 368: 364: 360: 356: 353: 352: 340: 339: 331: 320: 314: 313: 310:RNA expression 302: 301: 298: 297: 289: 285: 284: 276: 273: 268: 262: 261: 252: 245: 239: 235: 234: 229: 223: 222: 214: 213: 201: 200: 197: 196: 188: 184: 183: 175: 172: 167: 161: 160: 151: 144: 138: 134: 133: 126: 120: 119: 111: 110: 98: 97: 54: 50: 49: 41: 33: 32: 28: 27: 24: 23: 15: 9: 6: 4: 3: 2: 4904: 4893: 4890: 4889: 4887: 4872: 4869: 4867: 4864: 4862: 4859: 4857: 4854: 4852: 4849: 4848: 4844: 4840: 4836: 4835: 4831: 4829: 4826: 4824: 4820: 4817: 4816: 4814: 4810: 4800: 4797: 4795: 4792: 4790: 4787: 4786: 4784: 4782: 4778: 4768: 4765: 4763: 4760: 4758: 4755: 4753: 4750: 4748: 4745: 4743: 4740: 4738: 4735: 4733: 4730: 4728: 4725: 4723: 4720: 4718: 4715: 4713: 4710: 4709: 4707: 4703: 4697: 4694: 4692: 4689: 4687: 4684: 4683: 4681: 4679: 4678:Protocadherin 4675: 4668: 4664: 4660: 4656: 4653: 4650: 4646: 4642: 4638: 4634: 4631: 4630: 4628: 4626: 4622: 4616: 4613: 4611: 4608: 4606: 4603: 4602: 4600: 4596: 4593: 4591: 4587: 4584: 4582: 4578: 4567: 4563: 4559: 4556: 4553: 4549: 4545: 4542: 4539: 4535: 4531: 4528: 4525: 4521: 4517: 4514: 4511: 4507: 4503: 4500: 4499: 4497: 4495: 4491: 4483: 4480: 4478: 4475: 4473: 4470: 4468: 4465: 4463: 4460: 4458: 4455: 4454: 4453: 4450: 4446: 4443: 4441: 4438: 4436: 4433: 4431: 4428: 4427: 4426: 4423: 4421: 4418: 4416: 4413: 4410: 4406: 4402: 4399: 4396: 4392: 4389: 4388: 4386: 4384: 4380: 4377: 4375: 4371: 4367: 4363: 4356: 4351: 4349: 4344: 4342: 4337: 4336: 4333: 4321: 4318: 4316: 4313: 4311: 4308: 4306: 4303: 4301: 4298: 4296: 4293: 4291: 4288: 4286: 4283: 4281: 4278: 4276: 4273: 4271: 4268: 4266: 4263: 4261: 4258: 4256: 4253: 4251: 4248: 4246: 4243: 4241: 4238: 4236: 4233: 4231: 4228: 4226: 4223: 4221: 4218: 4216: 4213: 4211: 4208: 4206: 4203: 4201: 4198: 4196: 4193: 4191: 4188: 4186: 4183: 4181: 4178: 4176: 4173: 4171: 4168: 4166: 4163: 4161: 4158: 4156: 4153: 4151: 4148: 4146: 4143: 4141: 4138: 4137: 4135: 4131: 4125: 4122: 4120: 4117: 4115: 4112: 4110: 4107: 4105: 4102: 4100: 4097: 4095: 4092: 4090: 4087: 4085: 4082: 4080: 4077: 4075: 4072: 4070: 4067: 4065: 4062: 4060: 4057: 4055: 4052: 4050: 4047: 4045: 4042: 4040: 4037: 4035: 4032: 4030: 4027: 4025: 4022: 4020: 4017: 4015: 4012: 4010: 4007: 4005: 4002: 4000: 3997: 3995: 3992: 3990: 3987: 3985: 3982: 3980: 3977: 3975: 3972: 3970: 3967: 3965: 3962: 3960: 3957: 3955: 3952: 3950: 3947: 3945: 3942: 3940: 3937: 3935: 3932: 3931: 3929: 3925: 3919: 3916: 3914: 3910: 3907: 3905: 3902: 3900: 3897: 3895: 3892: 3890: 3887: 3885: 3882: 3880: 3877: 3875: 3872: 3870: 3867: 3865: 3862: 3858: 3855: 3853: 3850: 3849: 3848: 3845: 3843: 3840: 3838: 3835: 3833: 3830: 3828: 3825: 3823: 3820: 3818: 3815: 3813: 3810: 3808: 3805: 3803: 3800: 3798: 3795: 3793: 3790: 3788: 3785: 3783: 3780: 3777: 3774: 3772: 3768: 3765: 3763: 3760: 3756: 3753: 3751: 3748: 3747: 3746: 3743: 3741: 3738: 3734: 3731: 3729: 3726: 3725: 3724: 3721: 3719: 3716: 3714: 3711: 3709: 3706: 3704: 3701: 3699: 3696: 3694: 3691: 3689: 3686: 3684: 3681: 3680: 3678: 3674: 3668: 3665: 3663: 3660: 3658: 3655: 3653: 3650: 3648: 3645: 3643: 3640: 3638: 3635: 3633: 3630: 3628: 3625: 3623: 3620: 3618: 3615: 3613: 3610: 3608: 3605: 3603: 3600: 3598: 3595: 3593: 3590: 3588: 3585: 3581: 3578: 3576: 3573: 3572: 3571: 3568: 3566: 3563: 3561: 3558: 3556: 3553: 3549: 3546: 3544: 3541: 3539: 3536: 3535: 3534: 3531: 3529: 3526: 3524: 3521: 3519: 3516: 3514: 3511: 3507: 3504: 3502: 3499: 3498: 3497: 3494: 3492: 3489: 3487: 3484: 3482: 3479: 3477: 3474: 3472: 3469: 3467: 3464: 3460: 3457: 3455: 3452: 3451: 3450: 3447: 3444: 3441: 3439: 3436: 3434: 3431: 3429: 3426: 3424: 3420: 3417: 3415: 3412: 3408: 3405: 3403: 3400: 3398: 3395: 3394: 3393: 3390: 3388: 3385: 3383: 3380: 3378: 3375: 3373: 3370: 3368: 3365: 3364: 3362: 3358: 3352: 3349: 3347: 3344: 3342: 3339: 3337: 3334: 3332: 3329: 3327: 3324: 3322: 3319: 3317: 3314: 3312: 3309: 3307: 3304: 3302: 3299: 3297: 3294: 3292: 3289: 3287: 3284: 3282: 3279: 3277: 3274: 3272: 3269: 3267: 3264: 3262: 3259: 3257: 3254: 3252: 3249: 3247: 3244: 3242: 3239: 3237: 3234: 3232: 3229: 3225: 3222: 3220: 3217: 3216: 3215: 3212: 3208: 3205: 3203: 3200: 3199: 3198: 3195: 3193: 3190: 3188: 3185: 3183: 3180: 3178: 3175: 3173: 3170: 3168: 3165: 3163: 3160: 3158: 3155: 3153: 3150: 3148: 3145: 3143: 3140: 3138: 3135: 3131: 3128: 3126: 3123: 3122: 3121: 3118: 3116: 3113: 3111: 3108: 3106: 3103: 3101: 3098: 3096: 3093: 3091: 3088: 3087: 3085: 3081: 3075: 3072: 3070: 3067: 3065: 3062: 3060: 3057: 3055: 3052: 3050: 3047: 3045: 3042: 3040: 3037: 3035: 3031: 3028: 3026: 3023: 3021: 3018: 3016: 3013: 3011: 3008: 3006: 3003: 2999: 2996: 2994: 2991: 2989: 2986: 2984: 2981: 2979: 2976: 2974: 2971: 2970: 2969: 2966: 2964: 2961: 2959: 2956: 2954: 2951: 2949: 2946: 2944: 2941: 2937: 2934: 2932: 2929: 2928: 2927: 2924: 2922: 2919: 2917: 2914: 2912: 2909: 2907: 2904: 2902: 2899: 2897: 2894: 2892: 2889: 2887: 2884: 2880: 2877: 2875: 2872: 2870: 2867: 2865: 2862: 2860: 2857: 2855: 2852: 2851: 2850: 2847: 2843: 2840: 2838: 2835: 2833: 2830: 2829: 2828: 2825: 2823: 2820: 2816: 2813: 2811: 2808: 2806: 2803: 2802: 2801: 2798: 2796: 2793: 2791: 2788: 2786: 2783: 2781: 2778: 2776: 2773: 2771: 2768: 2766: 2763: 2761: 2758: 2756: 2753: 2751: 2748: 2747: 2745: 2741: 2735: 2732: 2728: 2725: 2723: 2720: 2718: 2715: 2713: 2710: 2708: 2705: 2703: 2700: 2699: 2698: 2695: 2693: 2690: 2688: 2685: 2683: 2680: 2678: 2675: 2673: 2670: 2668: 2665: 2661: 2658: 2656: 2653: 2651: 2648: 2646: 2643: 2642: 2641: 2638: 2636: 2633: 2631: 2628: 2626: 2623: 2621: 2618: 2616: 2613: 2611: 2608: 2606: 2603: 2601: 2598: 2596: 2593: 2589: 2586: 2584: 2581: 2580: 2579: 2576: 2574: 2571: 2569: 2566: 2564: 2561: 2559: 2556: 2554: 2551: 2549: 2546: 2544: 2541: 2539: 2536: 2534: 2531: 2529: 2526: 2524: 2521: 2519: 2516: 2514: 2511: 2509: 2506: 2502: 2499: 2497: 2494: 2493: 2492: 2489: 2487: 2484: 2482: 2479: 2477: 2474: 2470: 2467: 2465: 2462: 2460: 2457: 2455: 2452: 2451: 2450: 2447: 2445: 2442: 2440: 2437: 2433: 2430: 2429: 2428: 2425: 2423: 2420: 2418: 2415: 2413: 2410: 2408: 2405: 2401: 2398: 2396: 2393: 2391: 2388: 2387: 2386: 2383: 2381: 2378: 2374: 2371: 2369: 2366: 2364: 2361: 2359: 2356: 2354: 2351: 2350: 2349: 2346: 2345: 2343: 2339: 2334: 2330: 2326: 2319: 2314: 2312: 2307: 2305: 2300: 2299: 2296: 2289: 2285: 2284: 2279: 2278: 2273: 2270: 2266: 2265:CD146+Antigen 2263: 2262: 2251: 2247: 2243: 2239: 2235: 2231: 2227: 2223: 2218: 2214: 2210: 2206: 2202: 2198: 2194: 2188: 2184: 2180: 2176: 2172: 2168: 2164: 2161:(3): 338–45. 2160: 2156: 2150: 2146: 2142: 2137: 2132: 2128: 2124: 2120: 2115: 2111: 2107: 2102: 2097: 2092: 2087: 2083: 2079: 2075: 2070: 2066: 2062: 2058: 2054: 2050: 2046: 2041: 2037: 2033: 2028: 2023: 2018: 2013: 2009: 2005: 2001: 1996: 1992: 1988: 1984: 1980: 1976: 1972: 1969:(5): 457–64. 1968: 1964: 1959: 1955: 1951: 1946: 1941: 1938:(5): 746–53. 1937: 1933: 1929: 1924: 1920: 1916: 1912: 1908: 1904: 1900: 1897:(9): 688–95. 1896: 1892: 1887: 1883: 1879: 1874: 1869: 1865: 1861: 1858:(1): 127–30. 1857: 1853: 1852:Haematologica 1849: 1844: 1840: 1836: 1832: 1828: 1823: 1818: 1815:(4): 788–98. 1814: 1810: 1806: 1801: 1797: 1793: 1788: 1783: 1779: 1775: 1772:(4): 1570–7. 1771: 1767: 1763: 1758: 1754: 1750: 1747:(6): 931–40. 1746: 1742: 1737: 1733: 1729: 1724: 1719: 1715: 1711: 1707: 1702: 1698: 1694: 1689: 1684: 1681:(5): 459–65. 1680: 1676: 1672: 1667: 1663: 1659: 1655: 1651: 1647: 1643: 1640:(5): 337–40. 1639: 1635: 1630: 1626: 1622: 1617: 1612: 1608: 1604: 1600: 1596: 1592: 1587: 1583: 1579: 1575: 1571: 1566: 1561: 1557: 1553: 1549: 1544: 1540: 1536: 1531: 1526: 1522: 1518: 1514: 1509: 1505: 1501: 1496: 1491: 1487: 1483: 1479: 1475: 1471: 1466: 1465: 1452: 1448: 1443: 1438: 1434: 1430: 1426: 1419: 1417: 1408: 1404: 1400: 1396: 1392: 1388: 1381: 1373: 1369: 1365: 1361: 1356: 1351: 1348:(4): 788–98. 1347: 1343: 1339: 1332: 1324: 1320: 1315: 1310: 1307:(5): 642–54. 1306: 1302: 1298: 1291: 1283: 1279: 1274: 1269: 1265: 1261: 1258:(4): 319–27. 1257: 1253: 1249: 1242: 1234: 1230: 1225: 1220: 1215: 1210: 1206: 1202: 1198: 1191: 1183: 1179: 1174: 1169: 1166:(8): 2923–4. 1165: 1161: 1157: 1150: 1142: 1138: 1133: 1128: 1123: 1118: 1114: 1110: 1107:(7): e40443. 1106: 1102: 1098: 1091: 1083: 1079: 1075: 1071: 1067: 1063: 1059: 1055: 1051: 1044: 1036: 1032: 1026: 1018: 1014: 1008: 1001: 997: 992: 990: 988: 980: 976: 971: 969: 967: 962: 955: 952: 948: 944: 940: 939:keratinocytes 936: 931: 927: 923: 918: 917:progression. 916: 915:breast cancer 906: 902: 898: 896: 890: 888: 884: 880: 876: 865: 863: 860: 856: 852: 848: 844: 840: 836: 824: 819: 815: 811: 808: 804: 797: 795: 792: 788: 784: 780: 777: 773: 769: 762: 760: 756: 750: 746: 743: 737: 735: 729: 725: 722: 718: 711: 709: 705: 699: 695: 692: 686: 684: 678: 674: 671: 669:RefSeq (mRNA) 667: 660: 659: 654: 650: 647: 641: 640: 635: 631: 628: 626: 622: 615: 614: 609: 605: 602: 596: 595: 590: 586: 583: 581: 577: 570: 569: 564: 560: 557: 551: 550: 545: 541: 538: 536: 532: 529: 526: 524: 521: 517: 514: 510: 506: 494: 489: 486: 484: 480: 472: 467: 456: 452: 448: 444: 440: 436: 432: 428: 424: 420: 419: 416: 412: 407: 404: 394: 390: 386: 382: 378: 374: 370: 366: 362: 358: 357: 354: 350: 345: 342: 341: 338: 336: 332: 330: 329: 325: 324: 321: 319: 315: 311: 307: 303: 295: 290: 286: 282: 277: 271:9|9 A5.1 267: 263: 256: 249: 243: 236: 228: 224: 220: 215: 211: 206: 202: 194: 189: 185: 181: 176: 166: 162: 155: 148: 142: 135: 131: 125: 121: 117: 112: 108: 103: 99: 95: 91: 87: 83: 79: 75: 71: 67: 63: 59: 51: 46: 39: 34: 29: 25: 20: 4865: 4832: 3846: 3766: 3744: 3722: 3569: 3532: 3495: 3448: 3418: 3391: 3335: 3213: 3119: 2967: 2696: 2448: 2282: 2276: 2228:(1): 58–64. 2225: 2221: 2196: 2192: 2158: 2154: 2126: 2122: 2081: 2077: 2048: 2044: 2007: 2003: 1966: 1962: 1935: 1931: 1894: 1890: 1855: 1851: 1812: 1808: 1769: 1765: 1744: 1740: 1713: 1709: 1678: 1674: 1637: 1633: 1598: 1594: 1555: 1551: 1520: 1516: 1477: 1473: 1435:(3): 150–9. 1432: 1428: 1393:(2): 130–6. 1390: 1386: 1380: 1345: 1341: 1331: 1304: 1300: 1290: 1255: 1251: 1241: 1204: 1200: 1190: 1163: 1159: 1149: 1104: 1100: 1090: 1060:(3–4): 258. 1057: 1053: 1043: 1034: 1025: 1016: 1007: 919: 912: 903: 899: 891: 871: 858: 850: 846: 842: 834: 833: 759:NP_001346459 752: 731: 708:NM_001359530 701: 680: 656: 637: 611: 592: 566: 547: 527: 522: 333: 326: 191:119,321,521 178:119,308,529 53:External IDs 4655:Desmocollin 1558:(1): 4–11. 922:melanocytes 887:endothelium 879:angioblasts 292:44,054,024 279:44,045,766 31:Identifiers 4828:L-selectin 4799:P-selectin 4794:L-selectin 4789:E-selectin 4712:T-cadherin 4633:Desmoglein 4625:Desmosomal 2331:(see also 1809:Stem Cells 1480:(1): 148. 1342:Stem Cells 1002:, May 2017 981:, May 2017 958:References 951:E-cadherin 449:belly cord 337:(ortholog) 74:HomoloGene 4781:Selectins 4598:Classical 4590:Cadherins 4494:Integrins 4425:L1 family 2084:(1): R1. 1991:205448423 1963:Pathology 943:epidermis 755:NP_075548 734:NP_006491 704:NM_023061 683:NM_006500 513:Orthologs 82:GeneCards 4886:Category 4834:integrin 4383:IgSF CAM 2325:Proteins 2250:34180131 2242:18175063 2213:19782948 2183:43210730 2175:18160586 2145:17872908 2110:19123925 2065:19200179 2036:19703903 1983:18604730 1954:19229070 1919:23385606 1911:18834073 1882:19029148 1839:45009922 1831:20127798 1796:19221091 1753:19034879 1732:18029348 1697:12496470 1662:43280514 1625:18922915 1582:43326956 1574:10451481 1539:17982057 1504:32782280 1451:15892711 1407:19356677 1372:45009922 1364:20127798 1323:18295964 1282:21959269 1233:17999761 1182:16204154 1141:22792325 1101:PLOS ONE 1082:37508075 1074:10702685 998:– 977:– 930:melanoma 868:Function 807:Wikidata 4133:301–350 3927:251–300 3879:CD240CE 3676:201–250 3360:151–200 3083:101–150 2101:2687703 2027:2781430 1873:2625423 1787:2752656 1654:8292890 1616:2718575 1495:7421905 1273:3223259 1224:2248207 1132:3391262 1109:Bibcode 1000:Ensembl 979:Ensembl 941:in the 920:Normal 625:UniProt 580:Ensembl 519:Species 312:pattern 170:11q23.3 70:1933966 38:Aliases 4696:PCDH19 4691:PCDH15 4562:ITGA2B 4452:Nectin 4430:L1-CAM 4420:PE-CAM 4415:VCAM-1 4140:CD300A 4099:CDw293 3884:CD240D 3745:CD213a 3723:CDw210 3688:CD202b 3662:CDw199 3657:CDw198 3311:CD140b 2743:51–100 2274:Human 2271:(MeSH) 2248:  2240:  2211:  2181:  2173:  2143:  2108:  2098:  2063:  2034:  2024:  1989:  1981:  1952:  1917:  1909:  1880:  1870:  1837:  1829:  1794:  1784:  1751:  1730:  1695:  1660:  1652:  1623:  1613:  1580:  1572:  1537:  1502:  1492:  1449:  1405:  1370:  1362:  1321:  1280:  1270:  1231:  1221:  1207:: 29. 1180:  1139:  1129:  1080:  1072:  935:dermis 793:search 791:PubMed 658:Q8R2Y2 639:P43121 535:Entrez 483:BioGPS 433:atrium 62:155735 4871:EpCAM 4866:CD146 4843:LFA-1 4839:VLA-4 4812:Other 4767:CDH10 4757:CDH17 4752:CDH16 4747:CDH15 4742:CDH12 4737:CDH11 4686:PCDH1 4566:ITGB3 4548:CD49d 4544:VLA-4 4534:CD11b 4520:CD11c 4506:CD11a 4502:LFA-1 4482:CD155 4477:CADM3 4472:CADM1 4467:PVRL3 4462:PVRL2 4457:PVRL1 4440:NFASC 4435:NRCAM 4391:N-CAM 4320:CD350 4315:CD349 4310:CD344 4305:CD340 4300:CD339 4295:CD338 4290:CD337 4285:CD336 4280:CD335 4275:CD334 4270:CD333 4265:CD332 4260:CD331 4255:CD329 4250:CD328 4245:CD327 4240:CD326 4235:CD325 4230:CD324 4225:CD322 4220:CD321 4215:CD320 4210:CD318 4205:CD317 4200:CD316 4195:CD315 4190:CD314 4185:CD312 4180:CD309 4175:CD307 4170:CD306 4165:CD305 4160:CD304 4155:CD303 4150:CD302 4145:CD301 4124:CD299 4119:CD298 4114:CD297 4109:CD295 4104:CD294 4094:CD292 4089:CD290 4084:CD289 4079:CD288 4074:CD286 4069:CD284 4064:CD283 4059:CD282 4054:CD281 4049:CD280 4044:CD279 4039:CD278 4034:CD276 4029:CD275 4024:CD274 4019:CD273 4014:CD272 4009:CD271 4004:CD269 3999:CD268 3994:CD267 3989:CD266 3984:CD265 3979:CD264 3974:CD263 3969:CD262 3964:CD261 3959:CD258 3954:CD257 3949:CD256 3944:CD254 3939:CD253 3934:CD252 3918:CD249 3913:CD248 3909:CD247 3904:CD246 3899:CD244 3894:CD243 3889:CD241 3874:CD239 3869:CD238 3864:CD236 3847:CD235 3842:CD234 3837:CD233 3832:CD230 3827:CD229 3822:CD228 3817:CD227 3812:CD226 3807:CD225 3802:CD224 3797:CD223 3792:CD222 3787:CD221 3782:CD220 3767:CD218 3762:CD217 3740:CD212 3718:CD209 3713:CD208 3708:CD207 3703:CD206 3698:CD205 3693:CD204 3683:CD201 3667:CD200 3652:CD197 3647:CD196 3642:CD195 3637:CD194 3632:CD193 3627:CD192 3622:CD191 3617:CD186 3612:CD185 3607:CD184 3602:CD183 3597:CD182 3592:CD181 3587:CD180 3570:CD179 3565:CD178 3560:CD177 3555:CD174 3533:CD172 3528:CD171 3523:CD170 3518:CD169 3513:CD168 3496:CD167 3491:CD166 3486:CD164 3481:CD163 3476:CD162 3471:CD161 3466:CD160 3449:CD159 3419:CD158 3414:CD157 3392:CD156 3387:CD155 3382:CD154 3377:CD153 3372:CD152 3367:CD151 3351:CD150 3346:CD148 3341:CD147 3336:CD146 3331:CD144 3326:CD143 3321:CD142 3316:CD141 3306:CD138 3301:CD137 3296:CD136 3291:CD135 3286:CD134 3281:CD133 3276:CD132 3271:CD131 3266:CD130 3261:CD129 3256:CD127 3251:CD126 3246:CD125 3241:CD124 3236:CD123 3231:CD122 3214:CD121 3197:CD120 3192:CD119 3187:CD118 3182:CD117 3177:CD116 3172:CD115 3167:CD114 3162:CD113 3157:CD112 3152:CD111 3147:CD110 3142:CD109 3137:CD108 3120:CD107 3115:CD106 3110:CD105 3105:CD104 3100:CD103 3095:CD102 3090:CD101 3074:CD100 2246:S2CID 2179:S2CID 1987:S2CID 1915:S2CID 1835:S2CID 1658:S2CID 1578:S2CID 1368:S2CID 1160:Blood 1078:S2CID 849:) or 835:CD146 568:84004 528:Mouse 523:Human 335:Mouse 328:Human 275:Start 210:Mouse 174:Start 107:Human 4861:CD44 4856:CD24 4823:CD44 4762:CDH9 4732:CDH8 4727:CDH6 4722:CDH5 4717:CDH4 4667:DSC3 4663:DSC2 4659:DSC1 4649:DSG4 4645:DSG3 4641:DSG2 4637:DSG1 4615:CDH3 4610:CDH2 4605:CDH1 4552:CD29 4538:CD18 4524:CD18 4510:CD18 4445:CHL1 4401:ICAM 3069:CD99 3064:CD98 3059:CD97 3054:CD96 3049:CD95 3044:CD94 3039:CD93 3034:CD92 3030:CD91 3025:CD90 3020:CD89 3015:CD88 3010:CD87 3005:CD86 2968:CD85 2963:CD84 2958:CD83 2953:CD82 2948:CD81 2943:CD80 2926:CD79 2921:CD78 2916:CD74 2911:CD73 2906:CD72 2901:CD71 2896:CD70 2891:CD69 2886:CD68 2849:CD66 2827:CD64 2822:CD63 2800:CD62 2795:CD61 2790:CD59 2785:CD58 2780:CD57 2775:CD56 2770:CD55 2765:CD54 2760:CD53 2755:CD52 2750:CD51 2734:CD50 2697:CD49 2692:CD48 2687:CD47 2682:CD46 2677:CD45 2672:CD44 2667:CD43 2640:CD42 2635:CD41 2630:CD40 2625:CD39 2620:CD38 2615:CD37 2610:CD36 2605:CD35 2600:CD34 2595:CD33 2578:CD32 2573:CD31 2568:CD30 2563:CD29 2558:CD28 2553:CD27 2548:CD26 2543:CD25 2538:CD24 2533:CD23 2528:CD22 2523:CD21 2518:CD20 2513:CD19 2508:CD18 2491:CD16 2486:CD15 2481:CD14 2476:CD13 2449:CD11 2444:CD10 2341:1–50 2283:MCAM 2277:MCAM 2238:PMID 2209:PMID 2171:PMID 2141:PMID 2106:PMID 2061:PMID 2032:PMID 1979:PMID 1950:PMID 1907:PMID 1878:PMID 1827:PMID 1792:PMID 1749:PMID 1728:PMID 1693:PMID 1650:PMID 1621:PMID 1570:PMID 1535:PMID 1500:PMID 1447:PMID 1403:PMID 1391:1795 1360:PMID 1319:PMID 1278:PMID 1229:PMID 1178:PMID 1137:PMID 1070:PMID 933:the 928:and 926:nevi 881:and 862:gene 859:MCAM 847:MCAM 549:4162 318:Bgee 266:Band 227:Chr. 165:Band 124:Chr. 86:MCAM 78:4742 58:OMIM 45:MCAM 22:MCAM 2439:CD9 2427:CD8 2422:CD7 2417:CD6 2412:CD5 2407:CD4 2385:CD3 2380:CD2 2353:a-c 2348:CD1 2230:doi 2201:doi 2163:doi 2131:doi 2096:PMC 2086:doi 2053:doi 2022:PMC 2012:doi 2008:284 1971:doi 1940:doi 1899:doi 1895:117 1868:PMC 1860:doi 1817:doi 1782:PMC 1774:doi 1718:doi 1683:doi 1642:doi 1611:PMC 1603:doi 1560:doi 1556:189 1525:doi 1521:179 1490:PMC 1482:doi 1437:doi 1395:doi 1350:doi 1309:doi 1268:PMC 1260:doi 1219:PMC 1209:doi 1168:doi 1164:106 1127:PMC 1117:doi 1062:doi 491:n/a 288:End 187:End 90:OMA 66:MGI 4888:: 4841:, 4821:: 4665:, 4661:, 4647:, 4643:, 4639:, 4407:, 4364:: 3911:- 3032:- 2373:1E 2368:1D 2363:1B 2358:1A 2327:: 2244:. 2236:. 2226:12 2224:. 2207:. 2197:41 2195:. 2177:. 2169:. 2159:14 2157:. 2139:. 2127:22 2125:. 2121:. 2104:. 2094:. 2082:11 2080:. 2076:. 2059:. 2049:38 2047:. 2030:. 2020:. 2006:. 2002:. 1985:. 1977:. 1967:40 1965:. 1948:. 1936:29 1934:. 1930:. 1913:. 1905:. 1893:. 1876:. 1866:. 1856:94 1854:. 1850:. 1833:. 1825:. 1813:28 1811:. 1807:. 1790:. 1780:. 1770:69 1768:. 1764:. 1745:21 1743:. 1726:. 1712:. 1708:. 1691:. 1677:. 1673:. 1656:. 1648:. 1636:. 1619:. 1609:. 1599:68 1597:. 1593:. 1576:. 1568:. 1554:. 1550:. 1533:. 1519:. 1515:. 1498:. 1488:. 1476:. 1472:. 1445:. 1433:18 1431:. 1427:. 1415:^ 1401:. 1389:. 1366:. 1358:. 1346:28 1344:. 1340:. 1317:. 1305:36 1303:. 1299:. 1276:. 1266:. 1256:37 1254:. 1250:. 1227:. 1217:. 1203:. 1199:. 1176:. 1162:. 1158:. 1135:. 1125:. 1115:. 1103:. 1099:. 1076:. 1068:. 1058:87 1056:. 1052:. 1033:. 1015:. 986:^ 965:^ 864:. 294:bp 281:bp 193:bp 180:bp 88:; 84:: 80:; 76:: 72:; 68:: 64:; 60:: 4845:) 4837:( 4669:) 4657:( 4651:) 4635:( 4568:) 4564:+ 4560:( 4554:) 4550:+ 4546:( 4540:) 4536:+ 4532:( 4526:) 4522:+ 4518:( 4512:) 4508:+ 4504:( 4411:) 4409:5 4405:1 4403:( 4397:) 4393:( 4354:e 4347:t 4340:v 3857:b 3852:a 3778:) 3776:b 3771:a 3769:( 3755:2 3750:1 3733:b 3728:a 3580:b 3575:a 3548:g 3543:b 3538:a 3506:b 3501:a 3459:c 3454:a 3445:) 3443:k 3438:i 3433:e 3428:d 3423:a 3421:( 3407:c 3402:b 3397:a 3224:b 3219:a 3207:b 3202:a 3130:b 3125:a 2998:k 2993:j 2988:h 2983:e 2978:d 2973:a 2936:b 2931:a 2879:f 2874:e 2869:d 2864:c 2859:b 2854:a 2842:C 2837:B 2832:A 2815:P 2810:L 2805:E 2727:f 2722:e 2717:d 2712:c 2707:b 2702:a 2660:d 2655:c 2650:b 2645:a 2588:B 2583:A 2501:B 2496:A 2469:d 2464:c 2459:b 2454:a 2432:a 2400:Ξ΅ 2395:Ξ΄ 2390:Ξ³ 2335:) 2317:e 2310:t 2303:v 2290:. 2252:. 2232:: 2215:. 2203:: 2185:. 2165:: 2147:. 2133:: 2112:. 2088:: 2067:. 2055:: 2038:. 2014:: 1993:. 1973:: 1956:. 1942:: 1921:. 1901:: 1884:. 1862:: 1841:. 1819:: 1798:. 1776:: 1755:. 1734:. 1720:: 1714:7 1699:. 1685:: 1679:1 1664:. 1644:: 1638:3 1627:. 1605:: 1584:. 1562:: 1541:. 1527:: 1506:. 1484:: 1478:5 1453:. 1439:: 1409:. 1397:: 1374:. 1352:: 1325:. 1311:: 1284:. 1262:: 1235:. 1211:: 1205:8 1184:. 1170:: 1143:. 1119:: 1111:: 1105:7 1084:. 1064:: 1037:. 1019:. 845:( 837:( 212:) 109:) 92::

Index

Aliases
MCAM
OMIM
155735
MGI
1933966
HomoloGene
4742
GeneCards
MCAM
OMA
MCAM - orthologs
Human
Chromosome 11 (human)
Chr.
Chromosome 11 (human)
Chromosome 11 (human)
Genomic location for MCAM
Genomic location for MCAM
Band
bp
bp
Mouse
Chromosome 9 (mouse)
Chr.
Chromosome 9 (mouse)
Genomic location for MCAM
Genomic location for MCAM
Band
bp

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