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Trisomic rescue

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results. If the retained chromosomes come from different parents (that is, one copy from each) then there are no phenotypic or genotypic anomalies. The mechanism of trisomic rescue has been well confirmed
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Inoue, Momoko; Kajiwara, Kazuhiro; Yamaguchi, Ayumi; Kiyono, Tohru; Samura, Osamu; Akutsu, Hidenori; Sago, Haruhiko; Okamoto, Aikou; Umezawa, Akihiro (June 2019).
89: 72:). Trisomic rescue may be a natural means to keep a fetus as viable as possible (though uniparental disomy may occur and result in syndromes such as 325: 111:"Trisomy rescue mechanism: the case of concomitant mosaic trisomy 14 and maternal uniparental disomy 14 in a 15‐year‐old girl" 160:"Formation of upd(7)mat by trisomic rescue: SNP array typing provides new insights in chromosomal nondisjunction" 318: 73: 349: 311: 344: 46:
chromosome complement. If both of the retained chromosomes come from the same parent, then
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may also be a natural means to keep fetal viability via restoration of a disomic zygote.
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Many trisomic conditions result in stillborn infants (major exceptions include trisomies
243: 210: 186: 159: 135: 110: 81: 47: 248: 230: 191: 140: 77: 269: 238: 222: 181: 171: 130: 122: 65: 295: 61: 226: 176: 338: 234: 69: 57:, and alternative mechanisms that occur in trisomies are rare in comparison. 252: 195: 144: 39: 35: 126: 291: 85: 283: 53: 43: 21: 208: 31: 84:). Indeed, spontaneous trisomic rescue has been observed 211:"Autonomous trisomic rescue of Down syndrome cells" 157: 336: 109:Balbeur, Samuel; et al. (2 February 2016). 30:) is a genetic phenomenon in which a fertilized 158:Chantot-Bastaraud, Sandra; et al. (2017). 319: 326: 312: 242: 185: 175: 134: 108: 337: 278: 270:Resources - Genetics Home Reference 13: 14: 361: 263: 282: 38:loses one of these chromosomes ( 202: 151: 102: 1: 95: 34:containing three copies of a 298:. You can help Knowledge by 7: 10: 366: 277: 227:10.1038/s41374-019-0230-0 177:10.1186/s13039-017-0329-1 215:Laboratory Investigation 164:Molecular Cytogenetics 115:Clinical Case Reports 28:trisomy zygote rescue 82:genetic imprinting 48:uniparental disomy 307: 306: 80:syndromes due to 357: 328: 321: 314: 286: 279: 257: 256: 246: 206: 200: 199: 189: 179: 155: 149: 148: 138: 127:10.1002/ccr3.501 106: 90:monosomic rescue 365: 364: 360: 359: 358: 356: 355: 354: 335: 334: 333: 332: 275: 266: 261: 260: 207: 203: 156: 152: 107: 103: 98: 19:(also known as 17:Trisomic rescue 12: 11: 5: 363: 353: 352: 350:Genetics stubs 347: 331: 330: 323: 316: 308: 305: 304: 287: 273: 272: 265: 264:External links 262: 259: 258: 221:(6): 885–897. 201: 150: 121:(3): 265–271. 100: 99: 97: 94: 9: 6: 4: 3: 2: 362: 351: 348: 346: 343: 342: 340: 329: 324: 322: 317: 315: 310: 309: 303: 301: 297: 294:article is a 293: 288: 285: 281: 280: 276: 271: 268: 267: 254: 250: 245: 240: 236: 232: 228: 224: 220: 216: 212: 205: 197: 193: 188: 183: 178: 173: 169: 165: 161: 154: 146: 142: 137: 132: 128: 124: 120: 116: 112: 105: 101: 93: 91: 88:. Similarly, 87: 83: 79: 75: 71: 67: 63: 58: 56: 55: 49: 45: 41: 37: 33: 29: 25: 23: 18: 345:Cytogenetics 300:expanding it 289: 274: 218: 214: 204: 167: 163: 153: 118: 114: 104: 74:Prader-Willi 59: 52: 42:) to form a 40:anaphase lag 27: 20: 16: 15: 339:Categories 170:(28): 28. 96:References 36:chromosome 235:1530-0307 292:genetics 253:30760866 196:28770003 145:27014449 86:in vitro 78:Angelman 244:6760570 187:5526280 136:4771849 54:in vivo 44:diploid 22:trisomy 251:  241:  233:  194:  184:  143:  133:  24:rescue 290:This 296:stub 249:PMID 231:ISSN 192:PMID 141:PMID 76:and 32:ovum 239:PMC 223:doi 182:PMC 172:doi 131:PMC 123:doi 26:or 341:: 247:. 237:. 229:. 219:99 217:. 213:. 190:. 180:. 168:10 166:. 162:. 139:. 129:. 117:. 113:. 70:21 68:, 66:18 64:, 62:13 327:e 320:t 313:v 302:. 255:. 225:: 198:. 174:: 147:. 125:: 119:4

Index

trisomy
ovum
chromosome
anaphase lag
diploid
uniparental disomy
in vivo
13
18
21
Prader-Willi
Angelman
genetic imprinting
in vitro
monosomic rescue
"Trisomy rescue mechanism: the case of concomitant mosaic trisomy 14 and maternal uniparental disomy 14 in a 15‐year‐old girl"
doi
10.1002/ccr3.501
PMC
4771849
PMID
27014449
"Formation of upd(7)mat by trisomic rescue: SNP array typing provides new insights in chromosomal nondisjunction"
doi
10.1186/s13039-017-0329-1
PMC
5526280
PMID
28770003
"Autonomous trisomic rescue of Down syndrome cells"

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