1025:
nickel, despite the aforementioned affinity. Notably, Mfrn1 appears to transport free iron ions as opposed to any sort of chelated iron complex. Additionally, Mfrn1 selects against divalent alkali ions. Mfrn1 and its paralog Mfrn2 have complementary functionalities, though the precise relationship is still uncertain. For example, heme production is restored by expression of Mfrn2 in cells silenced for Mfrn1 and by ectopic expression of Mfrn1 in nonerythroid cells silenced for Mfrn2, where Mfrn1 accumulates due to an increased protein half-life. In contrast, ectopic expression of Mfrn2 failed to restore heme product in erythroid cells silenced for Mfrn1 because Mfrn2 was unable to accumulate in mitochondria.
244:
221:
143:
118:
250:
149:
992:(MC) Superfamily, however, its metal cargo makes it distinct from other members of this family. Mfrn1 plays a key role in mitochondrial iron homeostasis as an iron transporter, importing ferrous iron from the intermembrane space of the mitochondria to the mitochondrial matrix for the biosynthesis of heme groups and Fe-S clusters. This process is tightly regulated, given the redox potential of Mitoferrin's iron cargo. Mfrn1 is paralogous to
1808:
Visconte V, Avishai N, Mahfouz R, Tabarroki A, Cowen J, Sharghi-Moshtaghin R, Hitomi M, Rogers HJ, Hasrouni E, Phillips J, Sekeres MA, Heuer AH, Saunthararajah Y, Barnard J, Tiu RV (January 2015). "Distinct iron architecture in SF3B1-mutant myelodysplastic syndrome patients is linked to an SLC25A37
1057:. Studies in mice revealed that total deletion of Mfrn1 resulted in embryonic lethality, while selective deletion in adults caused severe anemia as stated above. Expression mouse Mfrn1 rescued knockout zebrafish, indicating that the gene is highly evolutionarily conserved. The transcription factor,
1024:
has micromolar affinity for the following first-row transition metals: iron (II), manganese (II), cobalt (II), and nickel (II). Mfrn1 iron transport was reconstituted in proteoliposomes, where the protein was also able to transport manganese, cobalt, copper, and zinc, yet it discriminated against
1617:
Shaw GC, Cope JJ, Li L, Corson K, Hersey C, Ackermann GE, Gwynn B, Lambert AJ, Wingert RA, Traver D, Trede NS, Barut BA, Zhou Y, Minet E, Donovan A, Brownlie A, Balzan R, Weiss MJ, Peters LL, Kaplan J, Zon LI, Paw BH (March 2006). "Mitoferrin is essential for erythroid iron assimilation".
1231:
Shaw GC, Cope JJ, Li L, Corson K, Hersey C, Ackermann GE, Gwynn B, Lambert AJ, Wingert RA, Traver D, Trede NS, Barut BA, Zhou Y, Minet E, Donovan A, Brownlie A, Balzan R, Weiss MJ, Peters LL, Kaplan J, Zon LI, Paw BH (March 2006). "Mitoferrin is essential for erythroid iron assimilation".
1352:
Chung J, Anderson SA, Gwynn B, Deck KM, Chen MJ, Langer NB, Shaw GC, Huston NC, Boyer LF, Datta S, Paradkar PN, Li L, Wei Z, Lambert AJ, Sahr K, Wittig JG, Chen W, Lu W, Galy B, Schlaeger TM, Hentze MW, Ward DM, Kaplan J, Eisenstein RS, Peters LL, Paw BH (March 2014).
2106:
Otsuki T, Ota T, Nishikawa T, Hayashi K, Suzuki Y, Yamamoto J, Wakamatsu A, Kimura K, Sakamoto K, Hatano N, Kawai Y, Ishii S, Saito K, Kojima S, Sugiyama T, Ono T, Okano K, Yoshikawa Y, Aotsuka S, Sasaki N, Hattori A, Okumura K, Nagai K, Sugano S, Isogai T (2007).
1020:(or protoporphyrin ferrochelatase). Furthermore, ABC10 binding enhances the stability and functionality of Mfrn1, suggesting that transcriptional and post-translational mechanisms further regulate cellular and mitochondrial iron homeostasis. Recombinant Mfrn1
2015:
Hu RM, Han ZG, Song HD, Peng YD, Huang QH, Ren SX, Gu YJ, Huang CH, Li YB, Jiang CL, Fu G, Zhang QH, Gu BW, Dai M, Mao YF, Gao GF, Rong R, Ye M, Zhou J, Xu SH, Gu J, Shi JX, Jin WR, Zhang CK, Wu TM, Huang GY, Chen Z, Chen MD, Chen JL (August 2000).
4598:
4851:
257:
156:
3079:
3675:
2069:
Li QZ, Eckenrode S, Ruan QG, Wang CY, Shi JD, McIndoe RA, She JX (November 2001). "Rapid decrease of RNA level of a novel mouse mitochondria solute carrier protein (Mscp) gene at 4-5 weeks of age".
4362:
2984:
1033:
Mitoferrin-1 has been implicated in diseases associated with defective iron homeostasis, resulting in iron or porphyrin imbalances. Abnormal Mfrn1 expression, for example, may contribute to
4560:
4162:
1045:(specifically IRE-BP1) transcriptionally regulates porphyrin biogenesis, inhibiting it in the absence of Mfrn1. Mfrn1 has also been implicated in depression and myelodysplastic syndrome.
4130:
3150:
4009:
1986:
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library".
1000:
gene in humans. Mfrn1 is highly expressed in differentiating erythroid cells and in other tissues at low levels, while Mfrn2 is expressed ubiquitously in non-erythroid tissues.
4739:
4395:
2888:
2201:
4927:
4884:
2109:"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries"
4965:
679:
660:
79:
3188:
1773:
Huo YX, Huang L, Zhang DF, Yao YG, Fang YR, Zhang C, Luo XJ (December 2016). "Identification of SLC25A37 as a major depressive disorder risk gene".
1957:
Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides".
2177:
993:
1154:
1136:
5198:
2155:
3557:
4721:
4716:
4064:
4059:
3986:
3981:
3976:
3971:
3966:
3961:
3941:
3936:
3931:
3926:
3911:
3901:
3891:
3886:
3876:
3851:
3657:
3642:
3637:
3259:
3254:
3249:
2145:
1453:
Chen W, Paradkar PN, Li L, Pierce EL, Langer NB, Takahashi-Makise N, Hyde BB, Shirihai OS, Ward DM, Kaplan J, Paw BH (September 2009).
4975:
4942:
4909:
4899:
4866:
4861:
4795:
4676:
4628:
4618:
4575:
4539:
4534:
4501:
4496:
4491:
4486:
4477:
4472:
4467:
4439:
4429:
4420:
4415:
4410:
4245:
4230:
4225:
4210:
4177:
4144:
4054:
4014:
3771:
3743:
3728:
3723:
3718:
3695:
3690:
3538:
3534:
3525:
3483:
3307:
3297:
3287:
3219:
3165:
3099:
3084:
2918:
2913:
2908:
2759:
2660:
2655:
2625:
2549:
2544:
2539:
2466:
922:
915:
2860:
2850:
2835:
2797:
2792:
2610:
2534:
2461:
1852:
Amigo JD, Yu M, Troadec MB, Gwynn B, Cooney JD, Lambert AJ, Chi NC, Weiss MJ, Peters LL, Kaplan J, Cantor AB, Paw BH (April 2011).
1283:
1179:"Mitoferrin-2-dependent mitochondrial iron uptake sensitizes human head and neck squamous carcinoma cells to photodynamic therapy"
1042:
3463:
1455:"Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria"
4993:
4519:
1119:
5267:
2719:
2388:
1724:
Troadec MB, Warner D, Wallace J, Thomas K, Spangrude GJ, Phillips J, Khalimonchuk O, Paw BH, Ward DM, Kaplan J (May 2011).
3861:
3355:
2281:
2276:
2170:
1098:
1053:
The importance of
Mitoferrins in heme and Fe-S cluster biosynthesis was first discovered in the anemic zebrafish mutant
243:
5247:
5148:
4315:
3277:
2575:
2489:
2246:
1013:
220:
3340:
2416:
2261:
1123:
1102:
1513:"In vitro reconstitution, functional dissection, and mutational analysis of metal ion transport by mitoferrin-1"
5272:
5188:
5168:
5163:
5134:
3239:
3041:
3036:
2815:
2163:
1901:
Ren Y, Yang S, Tan G, Ye W, Liu D, Qian X, Ding Z, Zhong Y, Zhang J, Jiang D, Zhao Y, Lu J (January 11, 2018).
724:
3234:
3229:
3224:
3209:
3204:
3199:
3194:
1034:
1041:
enzyme. Selective deletion of Mfrn1 in adult mice led to severe anemia rather than porphyria likely because
705:
5158:
2185:
256:
155:
142:
117:
59:
2018:"Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning"
1903:"Reduction of mitoferrin results in abnormal development and extended lifespan in Caenorhabditis elegans"
1406:"Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis"
249:
148:
1854:"Identification of distal cis-regulatory elements at mouse mitoferrin loci using zebrafish transgenesis"
1567:"Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2"
1012:
synthesis are still unclear, however, Mitoferrin-1 has been shown to form oligomeric complexes with the
4082:
3713:
2585:
2194:
1298:
1065:, reduced Mfrn1 expression results in abnormal development and increased lifespans of roughly 50-80%.
5143:
3031:
46:
5193:
3015:
2782:
873:
869:
865:
800:
796:
792:
67:
5153:
4785:
3411:
2514:
1061:, directly regulates Mfrn1 expression in zebrafish via distal cis-regulatory Mfrn1 elements. In
898:
877:
839:
835:
814:
804:
788:
87:
50:, MFRN, MFRN1, MSC, MSCP, PRO1278, PRO1584, PRO2217, HT015, solute carrier family 25 member 37
5129:
4651:
3836:
3761:
3155:
3026:
3021:
2595:
2197:
1074:
989:
5226:
5221:
2590:
2029:
1627:
1241:
131:
8:
4818:
2524:
2299:
1009:
2033:
1631:
1245:
2580:
2094:
1929:
1902:
1878:
1853:
1834:
1750:
1725:
1698:
1673:
1651:
1591:
1566:
1539:
1512:
1481:
1454:
1430:
1405:
1381:
1354:
1331:
1265:
1205:
1178:
91:
1999:
594:
589:
584:
579:
563:
558:
553:
548:
532:
527:
2130:
2086:
2057:
2052:
2017:
2003:
1974:
1970:
1934:
1883:
1826:
1790:
1786:
1755:
1703:
1643:
1596:
1544:
1486:
1435:
1386:
1323:
1257:
1210:
39:
1838:
1672:
Wang Y, Langer NB, Shaw GC, Yang G, Li L, Kaplan J, Paw BH, Bloomer JR (July 2011).
1335:
71:
5021:
3122:
2186:
2120:
2098:
2078:
2047:
2037:
1995:
1966:
1924:
1914:
1873:
1865:
1818:
1782:
1745:
1737:
1693:
1685:
1655:
1635:
1586:
1578:
1534:
1524:
1476:
1466:
1425:
1417:
1376:
1366:
1313:
1269:
1249:
1200:
1190:
336:
267:
211:
166:
5105:
2190:
1919:
1741:
1689:
1674:"Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria"
1421:
311:
95:
1726:"Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria"
1159:
National Center for
Biotechnology Information, U.S. National Library of Medicine
1141:
National Center for
Biotechnology Information, U.S. National Library of Medicine
2022:
Proceedings of the
National Academy of Sciences of the United States of America
1459:
Proceedings of the
National Academy of Sciences of the United States of America
1318:
1038:
1017:
412:
2125:
2108:
1177:
Hung HI, Schwartz JM, Maldonado EN, Lemasters JJ, Nieminen AL (January 2013).
5261:
5121:
2149:
2082:
1355:"Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria"
514:
1529:
1471:
1371:
1195:
472:
350:
2134:
2090:
2061:
2042:
1938:
1887:
1830:
1794:
1759:
1707:
1647:
1600:
1548:
1490:
1439:
1390:
1327:
1261:
1214:
329:
108:
2007:
1978:
962:
957:
4744:
4200:
3796:
2997:
1869:
1822:
1582:
769:
750:
1639:
1253:
5180:
4338:
1565:
Paradkar PN, Zumbrennen KB, Paw BH, Ward DM, Kaplan J (February 2009).
228:
125:
75:
1985:
5117:
624:
295:
282:
194:
181:
83:
4711:
4706:
4701:
4633:
4250:
3991:
3956:
3951:
3946:
3921:
3916:
3906:
3896:
3881:
3871:
3866:
3856:
3846:
3841:
3831:
3821:
3816:
3811:
3652:
3647:
3632:
3627:
3622:
3617:
3612:
3607:
3377:
3244:
2571:
946:
5078:
5073:
5068:
5063:
5058:
5053:
5003:
4998:
4970:
4947:
4937:
4932:
4904:
4894:
4889:
4856:
4800:
4790:
4696:
4691:
4686:
4681:
4671:
4666:
4661:
4656:
4623:
4613:
4608:
4603:
4580:
4570:
4565:
4542:
4529:
4524:
4458:
4453:
4444:
4434:
4405:
4400:
4377:
4372:
4367:
4344:
4320:
4297:
4240:
4235:
4220:
4215:
4205:
4182:
4172:
4167:
4139:
4134:
4112:
4107:
4102:
4097:
4092:
4087:
4049:
4044:
4039:
4034:
4029:
4024:
4019:
3806:
3801:
3791:
3786:
3781:
3776:
3766:
3738:
3733:
3685:
3680:
3602:
3597:
3592:
3587:
3582:
3577:
3572:
3567:
3562:
3520:
3511:
3502:
3497:
3488:
3478:
3473:
3468:
3422:
3417:
3393:
3388:
3383:
3322:
3317:
3312:
3302:
3292:
3282:
3214:
3170:
3160:
3132:
3127:
3104:
3094:
3089:
3061:
3056:
3051:
3046:
2994:
2989:
2945:
2940:
2935:
2930:
2923:
2903:
2898:
2893:
2870:
2865:
2764:
2754:
2749:
2675:
2670:
2665:
2650:
2645:
2640:
2635:
2630:
2471:
2369:
2364:
2359:
2354:
2349:
1296:
978:
736:
691:
609:
605:
63:
5202:
4599:
System A & N, sodium-coupled neutral amino-acid transporter
4291:
3826:
3373:
2855:
2845:
2840:
2830:
2825:
2820:
2787:
2744:
2739:
2734:
2729:
2711:
2706:
2701:
2696:
2620:
2615:
2605:
2600:
2567:
2529:
2519:
2509:
2504:
2494:
2456:
2451:
2446:
2441:
2436:
2431:
2426:
2421:
2398:
2393:
2344:
2334:
2329:
2271:
2266:
2256:
2251:
1807:
1297:
Hentze MW, Muckenthaler MU, Galy B, Camaschella C (July 2010).
1058:
930:
646:
1176:
3350:
3345:
2499:
2339:
2324:
2319:
2314:
2309:
2304:
4833:
4828:
4823:
2724:
1510:
1284:"Entrez Gene: SLC25A37 solute carrier family 25, member 37"
985:
2247:
high affinity glutamate and neutral amino-acid transporter
1723:
2105:
1564:
2693:
cationic amino-acid transporter/glycoprotein-associated
319:
2718:
glycoprotein-associated/light or catalytic subunits of
1299:"Two to tango: regulation of Mammalian iron metabolism"
1008:
The molecular details of iron trafficking for heme and
1511:
Christenson ET, Gallegos AS, Banerjee A (March 2018).
1351:
484:
4852:
Na-independent, system-L like amino-acid transporter
1452:
2068:
1851:
1671:
1115:
1113:
1111:
1094:
1092:
1090:
1037:, a porphyrin disease linked to mutations in the
266:
165:
5259:
1772:
1616:
1230:
1108:
1087:
16:Protein-coding gene in the species Homo sapiens
1956:
1667:
1665:
1226:
1224:
1120:GRCm38: Ensembl release 89: ENSMUSG00000034248
2171:
2014:
1719:
1717:
1612:
1610:
1560:
1558:
1506:
1504:
1502:
1500:
1403:
1900:
1347:
1345:
1172:
1170:
1168:
3558:organic cation/anion/zwitterion transporter
1662:
1221:
1099:GRCh38: Ensembl release 89: ENSG00000147454
528:iron ion transmembrane transporter activity
3080:human Na-sulfate/carboxylate cotransporter
2178:
2164:
2146:United States National Library of Medicine
1714:
1607:
1555:
1497:
2124:
2051:
2041:
1928:
1918:
1877:
1749:
1697:
1590:
1538:
1528:
1480:
1470:
1429:
1380:
1370:
1342:
1317:
1204:
1194:
1165:
996:(Mfrn2), a 39 kDa protein encoded by the
423:fetal liver hematopoietic progenitor cell
2144:This article incorporates text from the
1809:splice variant with a retained intron".
1028:
3676:Na+-dependent ascorbic acid transporter
1404:Chen W, Dailey HA, Paw BH (July 2010).
1043:Iron-responsive element-binding protein
5260:
3464:Organic anion-transporting polypeptide
5103:
5042:
4767:
4520:proton-coupled amino-acid transporter
4273:
3445:
2966:
2720:heterodimeric amino-acid transporters
2389:heterodimeric amino-acid transporters
2228:
2213:
2159:
1276:
271:
232:
227:
170:
129:
124:
2985:proton coupled metal ion transporter
4561:sugar-phosphate/phosphate exchanger
4163:facilitative nucleoside transporter
1517:The Journal of Biological Chemistry
1359:The Journal of Biological Chemistry
1183:The Journal of Biological Chemistry
13:
4363:type II Na-phosphate cotransporter
2576:sodium:neurotransmitter symporters
1949:
595:iron import into the mitochondrion
533:transmembrane transporter activity
14:
5284:
4316:Vesicular glutamate transporter 1
3278:Vesicular glutamate transporter 1
3151:proton oligopeptide cotransporter
1048:
988:in humans. It is a member of the
1787:10.1016/j.jpsychires.2016.09.011
1014:ATP-binding cassette transporter
255:
248:
242:
219:
154:
147:
141:
116:
4131:Na-coupled nucleoside transport
4010:multifunctional anion exchanger
3341:vesicular monoamine transporter
1894:
1845:
1801:
1775:Journal of Psychiatric Research
1766:
1446:
1397:
1858:Molecular and Cellular Biology
1571:Molecular and Cellular Biology
1290:
1147:
1129:
564:integral component of membrane
473:More reference expression data
1:
5104:
4994:multidrug and toxin extrusion
4083:fatty acid transport proteins
2300:facilitative GLUT transporter
2000:10.1016/S0378-1119(97)00411-3
1080:
1035:Erythropoietic protoporphyria
240:
139:
4768:
4740:basolateral iron transporter
4396:nucleoside-sugar transporter
4274:
3446:
2967:
2889:sodium bile salt cotransport
2490:sodium glucose cotransporter
2214:
1971:10.1016/0378-1119(94)90802-8
1920:10.1371/journal.pone.0029666
1742:10.1182/blood-2010-11-319483
1690:10.1016/j.exphem.2011.05.003
1422:10.1182/blood-2009-12-259614
559:mitochondrial inner membrane
7:
5268:Genes on human chromosome 8
5043:
2229:
2195:membrane transport proteins
1068:
1003:
10:
5289:
4928:Putative sugar transporter
1319:10.1016/j.cell.2010.06.028
5243:
5179:
5116:
5112:
5099:
5049:
5038:
5014:
4986:
4958:
4920:
4877:
4844:
4811:
4778:
4774:
4763:
4732:
4644:
4591:
4553:
4512:
4388:
4355:
4331:
4308:
4284:
4280:
4269:
4193:
4155:
4123:
4075:
4002:
3754:
3706:
3668:
3550:
3456:
3452:
3441:
3404:
3366:
3333:
3270:
3181:
3143:
3115:
3072:
3008:
2977:
2973:
2962:
2881:
2808:
2775:
2686:
2560:
2482:
2409:
2380:
2292:
2239:
2235:
2224:
2220:
2209:
1155:"Mouse PubMed Reference:"
1137:"Human PubMed Reference:"
961:
956:
952:
945:
929:
910:
895:
891:
862:
858:
851:
832:
828:
811:
787:
780:
767:
763:
748:
744:
735:
722:
718:
703:
699:
690:
677:
673:
658:
654:
645:
630:
623:
619:
603:
513:
509:
497:
492:
483:
470:
419:
410:
381:mucosa of paranasal sinus
357:
348:
318:
310:
306:
289:
276:
239:
218:
209:
205:
188:
175:
138:
115:
106:
102:
57:
54:
44:
37:
32:
28:
23:
5248:solute carrier disorders
4885:Choline-like transporter
3016:electroneutral cation-Cl
2083:10.1007/s00335001-2075-1
923:Chr 14: 69.48 – 69.52 Mb
4786:Magnesium transporter E
2417:bicarbonate transporter
2126:10.1093/dnares/12.2.117
1678:Experimental Hematology
1530:10.1074/jbc.M117.817478
1472:10.1073/pnas.0904519106
1372:10.1074/jbc.M114.547778
1196:10.1074/jbc.M112.422667
981:that is encoded by the
916:Chr 8: 23.53 – 23.58 Mb
590:mitochondrial transport
5181:Antiporter (exchanger)
2043:10.1073/pnas.160270997
451:atrioventricular valve
5273:Solute carrier family
4652:metal ion transporter
3762:mitochondrial carrier
3412:type III Na-phosphate
1075:Solute carrier family
1029:Clinical Significance
990:Mitochondrial carrier
234:Chromosome 14 (mouse)
1870:10.1128/MCB.01010-10
1823:10.1038/leu.2014.170
1583:10.1128/MCB.01685-08
977:(Mfrn1) is a 38 kDa
585:iron ion homeostasis
132:Chromosome 8 (human)
96:SLC25A37 - orthologs
4819:Ammonia transporter
3714:Na/(Ca-K) exchanger
2034:2000PNAS...97.9543H
1640:10.1038/nature04512
1632:2006Natur.440...96S
1254:10.1038/nature04512
1246:2006Natur.440...96S
1010:Iron-sulfur cluster
4966:Folate transporter
2387:heavy subunits of
2148:, which is in the
725:ENSMUSG00000034248
573:Biological process
542:Cellular component
521:Molecular function
435:tibiofemoral joint
5255:
5254:
5239:
5238:
5235:
5234:
5095:
5094:
5091:
5090:
5087:
5086:
5034:
5033:
5030:
5029:
4759:
4758:
4755:
4754:
4265:
4264:
4261:
4260:
3437:
3436:
3433:
3432:
2958:
2957:
2954:
2953:
2187:Membrane proteins
1523:(10): 3819–3828.
972:
971:
968:
967:
941:
940:
906:
905:
885:
884:
847:
846:
822:
821:
776:
775:
757:
756:
731:
730:
712:
711:
686:
685:
667:
666:
615:
614:
505:
504:
501:
500:
479:
478:
466:
465:
404:
403:
302:
301:
201:
200:
5280:
5214:
5213:
5212:
5114:
5113:
5101:
5100:
5040:
5039:
5022:Heme transporter
4776:
4775:
4765:
4764:
4282:
4281:
4271:
4270:
3454:
3453:
3443:
3442:
3123:urea transporter
2975:
2974:
2964:
2963:
2237:
2236:
2226:
2225:
2222:
2221:
2211:
2210:
2191:carrier proteins
2180:
2173:
2166:
2157:
2156:
2138:
2128:
2102:
2071:Mammalian Genome
2065:
2055:
2045:
2011:
1982:
1943:
1942:
1932:
1922:
1898:
1892:
1891:
1881:
1849:
1843:
1842:
1805:
1799:
1798:
1770:
1764:
1763:
1753:
1736:(20): 5494–502.
1721:
1712:
1711:
1701:
1669:
1660:
1659:
1626:(7080): 96–100.
1614:
1605:
1604:
1594:
1562:
1553:
1552:
1542:
1532:
1508:
1495:
1494:
1484:
1474:
1450:
1444:
1443:
1433:
1401:
1395:
1394:
1384:
1374:
1349:
1340:
1339:
1321:
1303:
1294:
1288:
1287:
1280:
1274:
1273:
1240:(7080): 96–100.
1228:
1219:
1218:
1208:
1198:
1174:
1163:
1162:
1151:
1145:
1144:
1133:
1127:
1117:
1106:
1096:
954:
953:
925:
918:
901:
889:
888:
880:
856:
855:
852:RefSeq (protein)
842:
826:
825:
817:
785:
784:
761:
760:
742:
741:
716:
715:
697:
696:
671:
670:
652:
651:
621:
620:
511:
510:
490:
489:
475:
415:
413:Top expressed in
408:
407:
353:
351:Top expressed in
346:
345:
325:
324:
308:
307:
298:
285:
274:
259:
252:
246:
235:
223:
207:
206:
197:
184:
173:
158:
151:
145:
134:
120:
104:
103:
98:
49:
42:
21:
20:
5288:
5287:
5283:
5282:
5281:
5279:
5278:
5277:
5258:
5257:
5256:
5251:
5231:
5211:
5208:
5207:
5206:
5204:
5175:
5138:
5108:
5083:
5045:
5026:
5010:
4982:
4954:
4916:
4873:
4840:
4807:
4770:
4751:
4728:
4640:
4587:
4549:
4508:
4384:
4351:
4327:
4304:
4276:
4257:
4189:
4151:
4119:
4071:
3998:
3750:
3702:
3664:
3546:
3448:
3429:
3400:
3362:
3329:
3266:
3189:monocarboxylate
3177:
3139:
3111:
3068:
3004:
2969:
2950:
2877:
2804:
2783:Na/Ca exchanger
2771:
2682:
2556:
2478:
2405:
2376:
2288:
2231:
2216:
2205:
2184:
2141:
1994:(1–2): 149–56.
1952:
1950:Further reading
1947:
1946:
1899:
1895:
1850:
1846:
1806:
1802:
1771:
1767:
1722:
1715:
1670:
1663:
1615:
1608:
1563:
1556:
1509:
1498:
1465:(38): 16263–8.
1451:
1447:
1402:
1398:
1365:(11): 7835–43.
1350:
1343:
1301:
1295:
1291:
1282:
1281:
1277:
1229:
1222:
1175:
1166:
1153:
1152:
1148:
1135:
1134:
1130:
1118:
1109:
1097:
1088:
1083:
1071:
1051:
1031:
1006:
963:View/Edit Mouse
958:View/Edit Human
921:
914:
911:Location (UCSC)
897:
876:
872:
868:
864:
838:
834:
813:
807:
803:
799:
795:
791:
706:ENSG00000147454
599:
568:
537:
471:
462:
457:
453:
449:
445:
441:
437:
433:
429:
425:
411:
400:
395:
391:
387:
383:
379:
375:
371:
367:
363:
361:trabecular bone
349:
293:
280:
272:
262:
261:
260:
253:
233:
210:Gene location (
192:
179:
171:
161:
160:
159:
152:
130:
107:Gene location (
58:
45:
38:
17:
12:
11:
5:
5286:
5276:
5275:
5270:
5253:
5252:
5244:
5241:
5240:
5237:
5236:
5233:
5232:
5230:
5229:
5224:
5219:
5218:
5217:
5209:
5191:
5185:
5183:
5177:
5176:
5174:
5173:
5172:
5171:
5166:
5156:
5151:
5146:
5141:
5136:
5132:
5126:
5124:
5110:
5109:
5097:
5096:
5093:
5092:
5089:
5088:
5085:
5084:
5082:
5081:
5076:
5071:
5066:
5061:
5056:
5050:
5047:
5046:
5036:
5035:
5032:
5031:
5028:
5027:
5025:
5024:
5018:
5016:
5012:
5011:
5009:
5008:
5007:
5006:
5001:
4990:
4988:
4984:
4983:
4981:
4980:
4979:
4978:
4973:
4962:
4960:
4956:
4955:
4953:
4952:
4951:
4950:
4945:
4940:
4935:
4924:
4922:
4918:
4917:
4915:
4914:
4913:
4912:
4907:
4902:
4897:
4892:
4881:
4879:
4875:
4874:
4872:
4871:
4870:
4869:
4864:
4859:
4848:
4846:
4842:
4841:
4839:
4838:
4837:
4836:
4831:
4826:
4815:
4813:
4809:
4808:
4806:
4805:
4804:
4803:
4798:
4793:
4782:
4780:
4772:
4771:
4761:
4760:
4757:
4756:
4753:
4752:
4750:
4749:
4748:
4747:
4736:
4734:
4730:
4729:
4727:
4726:
4725:
4724:
4719:
4714:
4709:
4704:
4699:
4694:
4689:
4684:
4679:
4674:
4669:
4664:
4659:
4648:
4646:
4642:
4641:
4639:
4638:
4637:
4636:
4631:
4626:
4621:
4616:
4611:
4606:
4595:
4593:
4589:
4588:
4586:
4585:
4584:
4583:
4578:
4573:
4568:
4557:
4555:
4551:
4550:
4548:
4547:
4546:
4545:
4537:
4532:
4527:
4516:
4514:
4510:
4509:
4507:
4506:
4505:
4504:
4499:
4494:
4489:
4482:
4481:
4480:
4475:
4470:
4463:
4462:
4461:
4456:
4449:
4448:
4447:
4442:
4437:
4432:
4425:
4424:
4423:
4418:
4413:
4408:
4403:
4392:
4390:
4386:
4385:
4383:
4382:
4381:
4380:
4375:
4370:
4359:
4357:
4353:
4352:
4350:
4349:
4348:
4347:
4335:
4333:
4329:
4328:
4326:
4325:
4324:
4323:
4312:
4310:
4306:
4305:
4303:
4302:
4301:
4300:
4288:
4286:
4278:
4277:
4267:
4266:
4263:
4262:
4259:
4258:
4256:
4255:
4254:
4253:
4248:
4243:
4238:
4233:
4228:
4223:
4218:
4213:
4208:
4197:
4195:
4191:
4190:
4188:
4187:
4186:
4185:
4180:
4175:
4170:
4159:
4157:
4153:
4152:
4150:
4149:
4148:
4147:
4142:
4127:
4125:
4121:
4120:
4118:
4117:
4116:
4115:
4110:
4105:
4100:
4095:
4090:
4079:
4077:
4073:
4072:
4070:
4069:
4068:
4067:
4062:
4057:
4052:
4047:
4042:
4037:
4032:
4027:
4022:
4017:
4006:
4004:
4000:
3999:
3997:
3996:
3995:
3994:
3989:
3984:
3979:
3974:
3969:
3964:
3959:
3954:
3949:
3944:
3939:
3934:
3929:
3924:
3919:
3914:
3909:
3904:
3899:
3894:
3889:
3884:
3879:
3874:
3869:
3864:
3859:
3854:
3849:
3844:
3839:
3834:
3829:
3824:
3819:
3814:
3809:
3804:
3799:
3794:
3789:
3784:
3779:
3774:
3769:
3758:
3756:
3752:
3751:
3749:
3748:
3747:
3746:
3741:
3736:
3731:
3726:
3721:
3710:
3708:
3704:
3703:
3701:
3700:
3699:
3698:
3693:
3688:
3683:
3672:
3670:
3666:
3665:
3663:
3662:
3661:
3660:
3655:
3650:
3645:
3640:
3635:
3630:
3625:
3620:
3615:
3610:
3605:
3600:
3595:
3590:
3585:
3580:
3575:
3570:
3565:
3554:
3552:
3548:
3547:
3545:
3544:
3543:
3542:
3530:
3529:
3528:
3523:
3516:
3515:
3514:
3507:
3506:
3505:
3500:
3493:
3492:
3491:
3486:
3481:
3476:
3471:
3460:
3458:
3450:
3449:
3439:
3438:
3435:
3434:
3431:
3430:
3428:
3427:
3426:
3425:
3420:
3414:cotransporter
3408:
3406:
3402:
3401:
3399:
3398:
3397:
3396:
3391:
3386:
3370:
3368:
3364:
3363:
3361:
3360:
3359:
3358:
3353:
3348:
3337:
3335:
3331:
3330:
3328:
3327:
3326:
3325:
3320:
3315:
3310:
3305:
3300:
3295:
3290:
3285:
3274:
3272:
3268:
3267:
3265:
3264:
3263:
3262:
3257:
3252:
3247:
3242:
3237:
3232:
3227:
3222:
3217:
3212:
3207:
3202:
3197:
3185:
3183:
3179:
3178:
3176:
3175:
3174:
3173:
3168:
3163:
3158:
3147:
3145:
3141:
3140:
3138:
3137:
3136:
3135:
3130:
3119:
3117:
3113:
3112:
3110:
3109:
3108:
3107:
3102:
3097:
3092:
3087:
3076:
3074:
3070:
3069:
3067:
3066:
3065:
3064:
3059:
3054:
3049:
3044:
3039:
3034:
3029:
3024:
3018:cotransporter
3012:
3010:
3006:
3005:
3003:
3002:
3001:
3000:
2992:
2981:
2979:
2971:
2970:
2960:
2959:
2956:
2955:
2952:
2951:
2949:
2948:
2943:
2938:
2933:
2928:
2927:
2926:
2921:
2916:
2911:
2906:
2901:
2896:
2885:
2883:
2879:
2878:
2876:
2875:
2874:
2873:
2868:
2863:
2858:
2853:
2848:
2843:
2838:
2833:
2828:
2823:
2816:Na/H exchanger
2812:
2810:
2806:
2805:
2803:
2802:
2801:
2800:
2795:
2790:
2779:
2777:
2773:
2772:
2770:
2769:
2768:
2767:
2762:
2757:
2752:
2747:
2742:
2737:
2732:
2727:
2716:
2715:
2714:
2709:
2704:
2699:
2690:
2688:
2684:
2683:
2681:
2680:
2679:
2678:
2673:
2668:
2663:
2658:
2653:
2648:
2643:
2638:
2633:
2628:
2623:
2618:
2613:
2608:
2603:
2598:
2593:
2588:
2583:
2564:
2562:
2558:
2557:
2555:
2554:
2553:
2552:
2547:
2542:
2537:
2532:
2527:
2522:
2517:
2512:
2507:
2502:
2497:
2486:
2484:
2480:
2479:
2477:
2476:
2475:
2474:
2469:
2464:
2459:
2454:
2449:
2444:
2439:
2434:
2429:
2424:
2413:
2411:
2407:
2406:
2404:
2403:
2402:
2401:
2396:
2384:
2382:
2378:
2377:
2375:
2374:
2373:
2372:
2367:
2362:
2357:
2352:
2347:
2342:
2337:
2332:
2327:
2322:
2317:
2312:
2307:
2296:
2294:
2290:
2289:
2287:
2286:
2285:
2284:
2279:
2274:
2269:
2264:
2259:
2254:
2243:
2241:
2233:
2232:
2218:
2217:
2207:
2206:
2198:solute carrier
2183:
2182:
2175:
2168:
2160:
2140:
2139:
2103:
2066:
2028:(17): 9543–8.
2012:
1983:
1965:(1–2): 171–4.
1953:
1951:
1948:
1945:
1944:
1893:
1864:(7): 1344–56.
1844:
1800:
1765:
1713:
1661:
1606:
1577:(4): 1007–16.
1554:
1496:
1445:
1396:
1341:
1289:
1275:
1220:
1164:
1146:
1128:
1107:
1085:
1084:
1082:
1079:
1078:
1077:
1070:
1067:
1050:
1049:Animal Studies
1047:
1039:Ferrochelatase
1030:
1027:
1018:Ferrochelatase
1005:
1002:
970:
969:
966:
965:
960:
950:
949:
943:
942:
939:
938:
936:
934:
927:
926:
919:
912:
908:
907:
904:
903:
893:
892:
886:
883:
882:
860:
859:
853:
849:
848:
845:
844:
830:
829:
823:
820:
819:
809:
808:
782:
778:
777:
774:
773:
765:
764:
758:
755:
754:
746:
745:
739:
733:
732:
729:
728:
720:
719:
713:
710:
709:
701:
700:
694:
688:
687:
684:
683:
675:
674:
668:
665:
664:
656:
655:
649:
643:
642:
637:
632:
628:
627:
617:
616:
613:
612:
601:
600:
598:
597:
592:
587:
582:
576:
574:
570:
569:
567:
566:
561:
556:
551:
545:
543:
539:
538:
536:
535:
530:
524:
522:
518:
517:
507:
506:
503:
502:
499:
498:
495:
494:
487:
481:
480:
477:
476:
468:
467:
464:
463:
461:
460:
456:
452:
448:
444:
440:
436:
432:
428:
424:
420:
417:
416:
405:
402:
401:
399:
398:
394:
390:
389:jejunal mucosa
386:
382:
378:
374:
370:
366:
362:
358:
355:
354:
342:
341:
333:
322:
316:
315:
312:RNA expression
304:
303:
300:
299:
291:
287:
286:
278:
275:
270:
264:
263:
254:
247:
241:
237:
236:
231:
225:
224:
216:
215:
203:
202:
199:
198:
190:
186:
185:
177:
174:
169:
163:
162:
153:
146:
140:
136:
135:
128:
122:
121:
113:
112:
100:
99:
56:
52:
51:
43:
35:
34:
30:
29:
26:
25:
15:
9:
6:
4:
3:
2:
5285:
5274:
5271:
5269:
5266:
5265:
5263:
5250:
5249:
5242:
5228:
5225:
5223:
5220:
5216:
5200:
5197:
5196:
5195:
5192:
5190:
5187:
5186:
5184:
5182:
5178:
5170:
5167:
5165:
5162:
5161:
5160:
5157:
5155:
5152:
5150:
5147:
5145:
5142:
5140:
5133:
5131:
5128:
5127:
5125:
5123:
5122:Cotransporter
5119:
5115:
5111:
5107:
5102:
5098:
5080:
5077:
5075:
5072:
5070:
5067:
5065:
5062:
5060:
5057:
5055:
5052:
5051:
5048:
5041:
5037:
5023:
5020:
5019:
5017:
5013:
5005:
5002:
5000:
4997:
4996:
4995:
4992:
4991:
4989:
4985:
4977:
4974:
4972:
4969:
4968:
4967:
4964:
4963:
4961:
4957:
4949:
4946:
4944:
4941:
4939:
4936:
4934:
4931:
4930:
4929:
4926:
4925:
4923:
4919:
4911:
4908:
4906:
4903:
4901:
4898:
4896:
4893:
4891:
4888:
4887:
4886:
4883:
4882:
4880:
4876:
4868:
4865:
4863:
4860:
4858:
4855:
4854:
4853:
4850:
4849:
4847:
4843:
4835:
4832:
4830:
4827:
4825:
4822:
4821:
4820:
4817:
4816:
4814:
4810:
4802:
4799:
4797:
4794:
4792:
4789:
4788:
4787:
4784:
4783:
4781:
4777:
4773:
4766:
4762:
4746:
4743:
4742:
4741:
4738:
4737:
4735:
4731:
4723:
4720:
4718:
4715:
4713:
4710:
4708:
4705:
4703:
4700:
4698:
4695:
4693:
4690:
4688:
4685:
4683:
4680:
4678:
4675:
4673:
4670:
4668:
4665:
4663:
4660:
4658:
4655:
4654:
4653:
4650:
4649:
4647:
4643:
4635:
4632:
4630:
4627:
4625:
4622:
4620:
4617:
4615:
4612:
4610:
4607:
4605:
4602:
4601:
4600:
4597:
4596:
4594:
4590:
4582:
4579:
4577:
4574:
4572:
4569:
4567:
4564:
4563:
4562:
4559:
4558:
4556:
4552:
4544:
4541:
4538:
4536:
4533:
4531:
4528:
4526:
4523:
4522:
4521:
4518:
4517:
4515:
4511:
4503:
4500:
4498:
4495:
4493:
4490:
4488:
4485:
4484:
4483:
4479:
4476:
4474:
4471:
4469:
4466:
4465:
4464:
4460:
4457:
4455:
4452:
4451:
4450:
4446:
4443:
4441:
4438:
4436:
4433:
4431:
4428:
4427:
4426:
4422:
4419:
4417:
4414:
4412:
4409:
4407:
4404:
4402:
4399:
4398:
4397:
4394:
4393:
4391:
4387:
4379:
4376:
4374:
4371:
4369:
4366:
4365:
4364:
4361:
4360:
4358:
4354:
4346:
4343:
4342:
4340:
4337:
4336:
4334:
4330:
4322:
4319:
4318:
4317:
4314:
4313:
4311:
4307:
4299:
4296:
4295:
4293:
4290:
4289:
4287:
4283:
4279:
4272:
4268:
4252:
4249:
4247:
4244:
4242:
4239:
4237:
4234:
4232:
4229:
4227:
4224:
4222:
4219:
4217:
4214:
4212:
4209:
4207:
4204:
4203:
4202:
4199:
4198:
4196:
4192:
4184:
4181:
4179:
4176:
4174:
4171:
4169:
4166:
4165:
4164:
4161:
4160:
4158:
4154:
4146:
4143:
4141:
4138:
4137:
4136:
4132:
4129:
4128:
4126:
4122:
4114:
4111:
4109:
4106:
4104:
4101:
4099:
4096:
4094:
4091:
4089:
4086:
4085:
4084:
4081:
4080:
4078:
4074:
4066:
4063:
4061:
4058:
4056:
4053:
4051:
4048:
4046:
4043:
4041:
4038:
4036:
4033:
4031:
4028:
4026:
4023:
4021:
4018:
4016:
4013:
4012:
4011:
4008:
4007:
4005:
4001:
3993:
3990:
3988:
3985:
3983:
3980:
3978:
3975:
3973:
3970:
3968:
3965:
3963:
3960:
3958:
3955:
3953:
3950:
3948:
3945:
3943:
3940:
3938:
3935:
3933:
3930:
3928:
3925:
3923:
3920:
3918:
3915:
3913:
3910:
3908:
3905:
3903:
3900:
3898:
3895:
3893:
3890:
3888:
3885:
3883:
3880:
3878:
3875:
3873:
3870:
3868:
3865:
3863:
3860:
3858:
3855:
3853:
3850:
3848:
3845:
3843:
3840:
3838:
3835:
3833:
3830:
3828:
3825:
3823:
3820:
3818:
3815:
3813:
3810:
3808:
3805:
3803:
3800:
3798:
3795:
3793:
3790:
3788:
3785:
3783:
3780:
3778:
3775:
3773:
3770:
3768:
3765:
3764:
3763:
3760:
3759:
3757:
3753:
3745:
3742:
3740:
3737:
3735:
3732:
3730:
3727:
3725:
3722:
3720:
3717:
3716:
3715:
3712:
3711:
3709:
3705:
3697:
3694:
3692:
3689:
3687:
3684:
3682:
3679:
3678:
3677:
3674:
3673:
3671:
3667:
3659:
3656:
3654:
3651:
3649:
3646:
3644:
3641:
3639:
3636:
3634:
3631:
3629:
3626:
3624:
3621:
3619:
3616:
3614:
3611:
3609:
3606:
3604:
3601:
3599:
3596:
3594:
3591:
3589:
3586:
3584:
3581:
3579:
3576:
3574:
3571:
3569:
3566:
3564:
3561:
3560:
3559:
3556:
3555:
3553:
3549:
3540:
3536:
3533:
3532:
3531:
3527:
3524:
3522:
3519:
3518:
3517:
3513:
3510:
3509:
3508:
3504:
3501:
3499:
3496:
3495:
3494:
3490:
3487:
3485:
3482:
3480:
3477:
3475:
3472:
3470:
3467:
3466:
3465:
3462:
3461:
3459:
3455:
3451:
3444:
3440:
3424:
3421:
3419:
3416:
3415:
3413:
3410:
3409:
3407:
3403:
3395:
3392:
3390:
3387:
3385:
3382:
3381:
3379:
3375:
3372:
3371:
3369:
3365:
3357:
3354:
3352:
3349:
3347:
3344:
3343:
3342:
3339:
3338:
3336:
3332:
3324:
3321:
3319:
3316:
3314:
3311:
3309:
3306:
3304:
3301:
3299:
3296:
3294:
3291:
3289:
3286:
3284:
3281:
3280:
3279:
3276:
3275:
3273:
3269:
3261:
3258:
3256:
3253:
3251:
3248:
3246:
3243:
3241:
3238:
3236:
3233:
3231:
3228:
3226:
3223:
3221:
3218:
3216:
3213:
3211:
3208:
3206:
3203:
3201:
3198:
3196:
3193:
3192:
3190:
3187:
3186:
3184:
3180:
3172:
3169:
3167:
3164:
3162:
3159:
3157:
3154:
3153:
3152:
3149:
3148:
3146:
3142:
3134:
3131:
3129:
3126:
3125:
3124:
3121:
3120:
3118:
3114:
3106:
3103:
3101:
3098:
3096:
3093:
3091:
3088:
3086:
3083:
3082:
3081:
3078:
3077:
3075:
3071:
3063:
3060:
3058:
3055:
3053:
3050:
3048:
3045:
3043:
3040:
3038:
3035:
3033:
3030:
3028:
3025:
3023:
3020:
3019:
3017:
3014:
3013:
3011:
3007:
2999:
2996:
2993:
2991:
2988:
2987:
2986:
2983:
2982:
2980:
2976:
2972:
2965:
2961:
2947:
2944:
2942:
2939:
2937:
2934:
2932:
2929:
2925:
2922:
2920:
2917:
2915:
2912:
2910:
2907:
2905:
2902:
2900:
2897:
2895:
2892:
2891:
2890:
2887:
2886:
2884:
2880:
2872:
2869:
2867:
2864:
2862:
2859:
2857:
2854:
2852:
2849:
2847:
2844:
2842:
2839:
2837:
2834:
2832:
2829:
2827:
2824:
2822:
2819:
2818:
2817:
2814:
2813:
2811:
2807:
2799:
2796:
2794:
2791:
2789:
2786:
2785:
2784:
2781:
2780:
2778:
2774:
2766:
2763:
2761:
2758:
2756:
2753:
2751:
2748:
2746:
2743:
2741:
2738:
2736:
2733:
2731:
2728:
2726:
2723:
2722:
2721:
2717:
2713:
2710:
2708:
2705:
2703:
2700:
2698:
2695:
2694:
2692:
2691:
2689:
2685:
2677:
2674:
2672:
2669:
2667:
2664:
2662:
2659:
2657:
2654:
2652:
2649:
2647:
2644:
2642:
2639:
2637:
2634:
2632:
2629:
2627:
2624:
2622:
2619:
2617:
2614:
2612:
2609:
2607:
2604:
2602:
2599:
2597:
2594:
2592:
2589:
2587:
2584:
2582:
2579:
2578:
2577:
2573:
2569:
2566:
2565:
2563:
2559:
2551:
2548:
2546:
2543:
2541:
2538:
2536:
2533:
2531:
2528:
2526:
2523:
2521:
2518:
2516:
2513:
2511:
2508:
2506:
2503:
2501:
2498:
2496:
2493:
2492:
2491:
2488:
2487:
2485:
2481:
2473:
2470:
2468:
2465:
2463:
2460:
2458:
2455:
2453:
2450:
2448:
2445:
2443:
2440:
2438:
2435:
2433:
2430:
2428:
2425:
2423:
2420:
2419:
2418:
2415:
2414:
2412:
2408:
2400:
2397:
2395:
2392:
2391:
2390:
2386:
2385:
2383:
2379:
2371:
2368:
2366:
2363:
2361:
2358:
2356:
2353:
2351:
2348:
2346:
2343:
2341:
2338:
2336:
2333:
2331:
2328:
2326:
2323:
2321:
2318:
2316:
2313:
2311:
2308:
2306:
2303:
2302:
2301:
2298:
2297:
2295:
2291:
2283:
2280:
2278:
2275:
2273:
2270:
2268:
2265:
2263:
2260:
2258:
2255:
2253:
2250:
2249:
2248:
2245:
2244:
2242:
2238:
2234:
2227:
2223:
2219:
2212:
2208:
2203:
2199:
2196:
2192:
2188:
2181:
2176:
2174:
2169:
2167:
2162:
2161:
2158:
2154:
2153:
2151:
2150:public domain
2147:
2136:
2132:
2127:
2122:
2119:(2): 117–26.
2118:
2114:
2110:
2104:
2100:
2096:
2092:
2088:
2084:
2080:
2077:(11): 830–6.
2076:
2072:
2067:
2063:
2059:
2054:
2049:
2044:
2039:
2035:
2031:
2027:
2023:
2019:
2013:
2009:
2005:
2001:
1997:
1993:
1989:
1984:
1980:
1976:
1972:
1968:
1964:
1960:
1955:
1954:
1940:
1936:
1931:
1926:
1921:
1916:
1913:(1): e29666.
1912:
1908:
1904:
1897:
1889:
1885:
1880:
1875:
1871:
1867:
1863:
1859:
1855:
1848:
1840:
1836:
1832:
1828:
1824:
1820:
1817:(1): 188–95.
1816:
1812:
1804:
1796:
1792:
1788:
1784:
1780:
1776:
1769:
1761:
1757:
1752:
1747:
1743:
1739:
1735:
1731:
1727:
1720:
1718:
1709:
1705:
1700:
1695:
1691:
1687:
1684:(7): 784–94.
1683:
1679:
1675:
1668:
1666:
1657:
1653:
1649:
1645:
1641:
1637:
1633:
1629:
1625:
1621:
1613:
1611:
1602:
1598:
1593:
1588:
1584:
1580:
1576:
1572:
1568:
1561:
1559:
1550:
1546:
1541:
1536:
1531:
1526:
1522:
1518:
1514:
1507:
1505:
1503:
1501:
1492:
1488:
1483:
1478:
1473:
1468:
1464:
1460:
1456:
1449:
1441:
1437:
1432:
1427:
1423:
1419:
1416:(4): 628–30.
1415:
1411:
1407:
1400:
1392:
1388:
1383:
1378:
1373:
1368:
1364:
1360:
1356:
1348:
1346:
1337:
1333:
1329:
1325:
1320:
1315:
1311:
1307:
1300:
1293:
1285:
1279:
1271:
1267:
1263:
1259:
1255:
1251:
1247:
1243:
1239:
1235:
1227:
1225:
1216:
1212:
1207:
1202:
1197:
1192:
1189:(1): 677–86.
1188:
1184:
1180:
1173:
1171:
1169:
1160:
1156:
1150:
1142:
1138:
1132:
1125:
1121:
1116:
1114:
1112:
1104:
1100:
1095:
1093:
1091:
1086:
1076:
1073:
1072:
1066:
1064:
1060:
1056:
1046:
1044:
1040:
1036:
1026:
1023:
1019:
1015:
1011:
1001:
999:
995:
991:
987:
984:
980:
976:
964:
959:
955:
951:
948:
944:
937:
935:
932:
928:
924:
920:
917:
913:
909:
902:
900:
894:
890:
887:
881:
879:
875:
871:
867:
861:
857:
854:
850:
843:
841:
837:
831:
827:
824:
818:
816:
810:
806:
802:
798:
794:
790:
786:
783:
781:RefSeq (mRNA)
779:
772:
771:
766:
762:
759:
753:
752:
747:
743:
740:
738:
734:
727:
726:
721:
717:
714:
708:
707:
702:
698:
695:
693:
689:
682:
681:
676:
672:
669:
663:
662:
657:
653:
650:
648:
644:
641:
638:
636:
633:
629:
626:
622:
618:
611:
607:
602:
596:
593:
591:
588:
586:
583:
581:
580:ion transport
578:
577:
575:
572:
571:
565:
562:
560:
557:
555:
554:mitochondrion
552:
550:
547:
546:
544:
541:
540:
534:
531:
529:
526:
525:
523:
520:
519:
516:
515:Gene ontology
512:
508:
496:
491:
488:
486:
482:
474:
469:
458:
454:
450:
446:
443:body of femur
442:
438:
434:
430:
426:
422:
421:
418:
414:
409:
406:
396:
392:
388:
384:
380:
376:
372:
368:
364:
360:
359:
356:
352:
347:
344:
343:
340:
338:
334:
332:
331:
327:
326:
323:
321:
317:
313:
309:
305:
297:
292:
288:
284:
279:
273:14|14 D2
269:
265:
258:
251:
245:
238:
230:
226:
222:
217:
213:
208:
204:
196:
191:
187:
183:
178:
168:
164:
157:
150:
144:
137:
133:
127:
123:
119:
114:
110:
105:
101:
97:
93:
89:
85:
81:
77:
73:
69:
65:
61:
53:
48:
41:
36:
31:
27:
22:
19:
5245:
4341:transporter
4294:transporter
3380:transporter
3191:transporter
2574:- dependent
2143:
2142:
2116:
2113:DNA Research
2112:
2074:
2070:
2025:
2021:
1991:
1987:
1962:
1958:
1910:
1906:
1896:
1861:
1857:
1847:
1814:
1810:
1803:
1778:
1774:
1768:
1733:
1729:
1681:
1677:
1623:
1619:
1574:
1570:
1520:
1516:
1462:
1458:
1448:
1413:
1409:
1399:
1362:
1358:
1312:(1): 24–38.
1309:
1305:
1292:
1278:
1237:
1233:
1186:
1182:
1158:
1149:
1140:
1131:
1062:
1054:
1052:
1032:
1021:
1007:
997:
994:Mitoferrin-2
982:
975:Mitoferrin-1
974:
973:
896:
874:NP_001304743
870:NP_001304742
866:NP_001304741
863:
833:
812:
801:NM_001317814
797:NM_001317813
793:NM_001317812
768:
749:
723:
704:
678:
659:
639:
634:
335:
328:
55:External IDs
18:
4201:zinc efflux
1781:: 168–175.
1016:ABCB10 and
459:granulocyte
427:human fetus
397:pericardium
369:bone marrow
294:69,522,561
281:69,479,297
193:23,575,463
180:23,528,956
33:Identifiers
5262:Categories
5227:Cl-oxalate
5222:Cl-formate
5149:Na/glucose
4339:Acetyl-CoA
1126:, May 2017
1105:, May 2017
1081:References
1063:C. elegans
439:belly cord
339:(ortholog)
76:HomoloGene
5246:see also
5118:Symporter
5106:Ion pumps
899:NP_080607
878:NP_057696
840:NM_030054
836:NM_026331
815:NM_018586
805:NM_018579
789:NM_016612
625:Orthologs
377:vena cava
84:GeneCards
5215:(Band 3)
5199:Na/(Ca-K
4769:SLC41–48
4722:SLC39A14
4717:SLC39A13
4712:SLC39A12
4707:SLC39A11
4702:SLC39A10
4634:SLC38A10
4275:SLC31–40
4251:SLC30A10
4065:SLC26A11
4060:SLC26A10
3992:SLC25A46
3987:SLC25A45
3982:SLC25A44
3977:SLC25A43
3972:SLC25A42
3967:SLC25A41
3962:SLC25A40
3957:SLC25A39
3952:SLC25A38
3947:SLC25A37
3942:SLC25A36
3937:SLC25A35
3932:SLC25A34
3927:SLC25A33
3922:SLC25A32
3917:SLC25A31
3912:SLC25A30
3907:SLC25A29
3902:SLC25A28
3897:SLC25A27
3892:SLC25A26
3887:SLC25A25
3882:SLC25A24
3877:SLC25A23
3872:SLC25A22
3867:SLC25A21
3862:SLC25A20
3857:SLC25A19
3852:SLC25A18
3847:SLC25A17
3842:SLC25A16
3837:SLC25A15
3832:SLC25A14
3827:SLC25A13
3822:SLC25A12
3817:SLC25A11
3812:SLC25A10
3658:SLC22A20
3653:SLC22A19
3648:SLC22A18
3643:SLC22A17
3638:SLC22A16
3633:SLC22A15
3628:SLC22A14
3623:SLC22A13
3618:SLC22A12
3613:SLC22A11
3608:SLC22A10
3447:SLC21–30
3378:thiamine
3260:SLC16A14
3255:SLC16A13
3250:SLC16A12
3245:SLC16A11
3240:SLC16A10
2968:SLC11–20
2572:chloride
2215:By group
2135:16303743
2091:11845285
2062:10931946
1939:22253756
1907:PLOS ONE
1888:21248200
1839:10475563
1831:24854990
1811:Leukemia
1795:27643475
1760:21310927
1708:21627978
1648:16511496
1601:19075006
1549:29305420
1491:19805291
1440:20427704
1391:24509859
1336:23971474
1328:20603012
1262:16511496
1215:23135267
1122:–
1101:–
1069:See also
1055:frascati
1022:in vitro
1004:Function
998:SLC25A28
983:SLC25A37
947:Wikidata
604:Sources:
549:membrane
393:duodenum
373:monocyte
88:SLC25A37
47:SLC25A37
24:SLC25A37
5130:Na/K,Cl
5044:SLCO1–4
5004:SLC47A2
4999:SLC47A1
4976:SLC46A2
4971:SLC46A1
4948:SLC45A4
4943:SLC54A3
4938:SLC45A2
4933:SLC45A1
4910:SLC44A5
4905:SLC44A4
4900:SLC44A3
4895:SLC44A2
4890:SLC44A1
4867:SLC43A3
4862:SLC43A2
4857:SLC43A1
4801:SLC41A3
4796:SLC41A2
4791:SLC41A1
4745:SLC40A1
4697:SLC39A9
4692:SLC39A8
4687:SLC39A7
4682:SLC39A6
4677:SLC39A5
4672:SLC39A4
4667:SLC39A3
4662:SLC39A2
4657:SLC39A1
4629:SLC38A6
4624:SLC38A5
4619:SLC38A4
4614:SLC38A3
4609:SLC38A2
4604:SLC38A1
4581:SLC37A4
4576:SLC37A3
4571:SLC37A2
4566:SLC37A1
4540:SLC36A4
4535:SLC36A3
4530:SLC36A2
4525:SLC36A1
4502:SLC35E4
4497:SLC35E3
4492:SLC35E2
4487:SLC35E1
4478:SLC35D3
4473:SLC35D2
4468:SLC35D1
4459:SLC35C2
4454:SLC35C1
4445:SLC35B4
4440:SLC35B3
4435:SLC35B2
4430:SLC35B1
4421:SLC35A5
4416:SLC35A4
4411:SLC35A3
4406:SLC35A2
4401:SLC35A1
4378:SLC34A3
4373:SLC34A2
4368:SLC34A1
4345:SLC33A1
4321:SLC32A1
4298:SLC31A1
4246:SLC30A9
4241:SLC30A8
4236:SLC30A7
4231:SLC30A6
4226:SLC30A5
4221:SLC30A4
4216:SLC30A3
4211:SLC30A2
4206:SLC30A1
4183:SLC29A4
4178:SLC29A3
4173:SLC29A2
4168:SLC29A1
4145:SLC28A3
4140:SLC28A2
4135:SLC28A1
4113:SLC27A6
4108:SLC27A5
4103:SLC27A4
4098:SLC27A3
4093:SLC27A2
4088:SLC27A1
4055:SLC26A9
4050:SLC26A8
4045:SLC26A7
4040:SLC26A6
4035:SLC26A5
4030:SLC26A4
4025:SLC26A3
4020:SLC26A2
4015:SLC26A1
3807:SLC25A9
3802:SLC25A8
3797:SLC25A7
3792:SLC25A6
3787:SLC25A5
3782:SLC25A4
3777:SLC25A3
3772:SLC25A2
3767:SLC25A1
3744:SLC24A6
3739:SLC24A5
3734:SLC24A4
3729:SLC24A3
3724:SLC24A2
3719:SLC24A1
3696:SLC23A4
3691:SLC23A3
3686:SLC23A2
3681:SLC23A1
3603:SLC22A9
3598:SLC22A8
3593:SLC22A7
3588:SLC22A6
3583:SLC22A5
3578:SLC22A4
3573:SLC22A3
3568:SLC22A2
3563:SLC22A1
3539:SLCO6A1
3535:SLCO5A1
3526:SLCO4C1
3521:SLCO4A1
3512:SLCO3A1
3503:SLCO2B1
3498:SLCO2A1
3489:SLCO1C1
3484:SLCO1B4
3479:SLCO1B3
3474:SLCO1B1
3469:SLCO1A2
3423:SLC20A2
3418:SLC20A1
3394:SLC19A3
3389:SLC19A2
3384:SLC19A1
3356:SLC18A3
3351:SLC18A2
3346:SLC18A1
3323:SLC17A9
3318:SLC17A8
3313:SLC17A7
3308:SLC17A6
3303:SLC17A5
3298:SLC17A4
3293:SLC17A3
3288:SLC17A2
3283:SLC17A1
3235:SLC16A9
3230:SLC16A8
3225:SLC16A7
3220:SLC16A6
3215:SLC16A5
3210:SLC16A4
3205:SLC16A3
3200:SLC16A2
3195:SLC16A1
3171:SLC15A4
3166:SLC15A3
3161:SLC15A2
3156:SLC15A1
3133:SLC14A2
3128:SLC14A1
3105:SLC13A5
3100:SLC13A4
3095:SLC13A3
3090:SLC13A2
3085:SLC13A1
3062:SLC12A9
3057:SLC12A8
3052:SLC12A7
3047:SLC12A6
3042:SLC12A5
3037:SLC12A4
3032:SLC12A3
3027:SLC12A2
3022:SLC12A1
2995:SLC11A2
2990:SLC11A1
2924:SLC10A7
2919:SLC10A6
2914:SLC10A5
2909:SLC10A4
2904:SLC10A3
2899:SLC10A2
2894:SLC10A1
2871:SLC9A11
2866:SLC9A10
2765:SLC7A14
2760:SLC7A13
2755:SLC7A11
2750:SLC7A10
2676:SLC6A20
2671:SLC6A19
2666:SLC6A18
2661:SLC6A17
2656:SLC6A16
2651:SLC6A15
2646:SLC6A14
2641:SLC6A13
2636:SLC6A12
2631:SLC6A11
2626:SLC6A10
2230:SLC1–10
2099:1743722
2030:Bibcode
2008:9373149
1979:8125298
1930:3256167
1879:3135305
1751:3109720
1699:3143264
1656:4429335
1628:Bibcode
1592:2643804
1540:5846140
1482:2752562
1431:3324294
1382:4022844
1270:4429335
1242:Bibcode
1206:3537066
1124:Ensembl
1103:Ensembl
979:protein
737:UniProt
692:Ensembl
631:Species
610:QuickGO
314:pattern
72:1914962
40:Aliases
4292:copper
3374:folate
2861:SLC9A9
2856:SLC9A8
2851:SLC9A7
2846:SLC9A6
2841:SLC9A5
2836:SLC9A4
2831:SLC9A3
2826:SLC9A2
2821:SLC9A1
2798:SLC8A3
2793:SLC8A2
2788:SLC8A1
2745:SLC7A9
2740:SLC7A8
2735:SLC7A7
2730:SLC7A6
2725:SLC7A5
2712:SLC7A4
2707:SLC7A3
2702:SLC7A2
2697:SLC7A1
2621:SLC6A9
2616:SLC6A8
2611:SLC6A7
2606:SLC6A6
2601:SLC6A5
2596:SLC6A4
2591:SLC6A3
2586:SLC6A2
2581:SLC6A1
2570:- and
2568:sodium
2495:SLC5A1
2422:SLC4A1
2394:SLC3A1
2305:SLC2A1
2252:SLC1A1
2133:
2097:
2089:
2060:
2050:
2006:
1977:
1937:
1927:
1886:
1876:
1837:
1829:
1793:
1758:
1748:
1706:
1696:
1654:
1646:
1620:Nature
1599:
1589:
1547:
1537:
1489:
1479:
1438:
1428:
1389:
1379:
1334:
1326:
1268:
1260:
1234:Nature
1213:
1203:
1059:GATA-1
933:search
931:PubMed
770:Q920G8
751:Q9NYZ2
647:Entrez
485:BioGPS
455:atrium
447:spleen
172:8p21.2
64:610387
5194:Na/Ca
5144:Na/Cl
5015:(48):
4987:(47):
4959:(46):
4921:(45):
4878:(44):
4845:(43):
4812:(42):
4779:(41):
4733:(40):
4645:(39):
4592:(38):
4554:(37):
4513:(36):
4389:(35):
4356:(34):
4332:(33):
4309:(32):
4285:(31):
4194:(30):
4156:(29):
4124:(28):
4076:(27):
4003:(26):
3755:(25):
3707:(24):
3669:(23):
3551:(22):
3457:(21):
3405:(20):
3367:(19):
3334:(18):
3271:(17):
3182:(16):
3144:(15):
3116:(14):
3073:(13):
3009:(12):
2978:(11):
2882:(10):
2202:TC 2A
2095:S2CID
2053:16901
1835:S2CID
1730:Blood
1652:S2CID
1410:Blood
1332:S2CID
1302:(PDF)
1266:S2CID
680:67712
661:51312
640:Mouse
635:Human
606:Amigo
431:blood
385:sperm
365:blood
337:Mouse
330:Human
277:Start
212:Mouse
176:Start
109:Human
80:74739
5201:) -
5189:Na/H
5159:Cl/K
5154:Na/I
5135:Na/P
5079:O4A1
5074:O431
5069:O2B1
5064:O1B3
5059:O1B1
5054:O1A2
4834:RhCG
4829:RhBG
4824:RhAG
4543:36A2
2998:11A3
2946:10A7
2941:10A3
2936:10A2
2931:10A1
2809:(9):
2776:(8):
2687:(7):
2561:(6):
2483:(5):
2410:(4):
2381:(3):
2293:(2):
2240:(1):
2131:PMID
2087:PMID
2058:PMID
2004:PMID
1988:Gene
1975:PMID
1959:Gene
1935:PMID
1884:PMID
1827:PMID
1791:PMID
1756:PMID
1704:PMID
1644:PMID
1597:PMID
1545:PMID
1487:PMID
1436:PMID
1387:PMID
1324:PMID
1306:Cell
1258:PMID
1211:PMID
986:gene
320:Bgee
268:Band
229:Chr.
167:Band
126:Chr.
60:OMIM
5205:HCO
5203:Cl/
2121:doi
2079:doi
2048:PMC
2038:doi
1996:doi
1992:200
1967:doi
1963:138
1925:PMC
1915:doi
1874:PMC
1866:doi
1819:doi
1783:doi
1746:PMC
1738:doi
1734:117
1694:PMC
1686:doi
1636:doi
1624:440
1587:PMC
1579:doi
1535:PMC
1525:doi
1521:293
1477:PMC
1467:doi
1463:106
1426:PMC
1418:doi
1414:116
1377:PMC
1367:doi
1363:289
1314:doi
1310:142
1250:doi
1238:440
1201:PMC
1191:doi
1187:288
493:n/a
290:End
189:End
92:OMA
68:MGI
5264::
5120:,
2550:12
2545:11
2540:10
2472:11
2467:10
2370:14
2365:13
2360:12
2355:11
2350:10
2193::
2189:,
2129:.
2117:12
2115:.
2111:.
2093:.
2085:.
2075:12
2073:.
2056:.
2046:.
2036:.
2026:97
2024:.
2020:.
2002:.
1990:.
1973:.
1961:.
1933:.
1923:.
1909:.
1905:.
1882:.
1872:.
1862:31
1860:.
1856:.
1833:.
1825:.
1815:29
1813:.
1789:.
1779:83
1777:.
1754:.
1744:.
1732:.
1728:.
1716:^
1702:.
1692:.
1682:39
1680:.
1676:.
1664:^
1650:.
1642:.
1634:.
1622:.
1609:^
1595:.
1585:.
1575:29
1573:.
1569:.
1557:^
1543:.
1533:.
1519:.
1515:.
1499:^
1485:.
1475:.
1461:.
1457:.
1434:.
1424:.
1412:.
1408:.
1385:.
1375:.
1361:.
1357:.
1344:^
1330:.
1322:.
1308:.
1304:.
1264:.
1256:.
1248:.
1236:.
1223:^
1209:.
1199:.
1185:.
1181:.
1167:^
1157:.
1139:.
1110:^
1089:^
608:/
296:bp
283:bp
195:bp
182:bp
90:;
86::
82:;
78::
74:;
70::
66:;
62::
5210:3
5169:5
5164:4
5139:3
5137:i
4133:(
3541:)
3537:(
3376:/
2535:9
2530:8
2525:7
2520:6
2515:5
2510:4
2505:3
2500:2
2462:9
2457:8
2452:7
2447:6
2442:5
2437:4
2432:3
2427:2
2399:2
2345:9
2340:8
2335:7
2330:6
2325:5
2320:4
2315:3
2310:2
2282:7
2277:6
2272:5
2267:4
2262:3
2257:2
2204:)
2200:(
2179:e
2172:t
2165:v
2152:.
2137:.
2123::
2101:.
2081::
2064:.
2040::
2032::
2010:.
1998::
1981:.
1969::
1941:.
1917::
1911:7
1890:.
1868::
1841:.
1821::
1797:.
1785::
1762:.
1740::
1710:.
1688::
1658:.
1638::
1630::
1603:.
1581::
1551:.
1527::
1493:.
1469::
1442:.
1420::
1393:.
1369::
1338:.
1316::
1286:.
1272:.
1252::
1244::
1217:.
1193::
1161:.
1143:.
214:)
111:)
94::
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
